LOCUS       DAVHKZ010000001       234908 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000001 DAVHKZ010000000
VERSION     DAVHKZ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 234908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 234908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..234908
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.001"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            501..1292
                     /locus_tag="VVO74_000001"
     CDS             501..1292
                     /locus_tag="VVO74_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694109.1"
                     /translation="MNFALNKGEIVGQVGRNGVGKSTLMKILVQNNQPTSGNIISSDN
                     VGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLSVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKEMLKDIYLNRSK"
     gene            1308..2036
                     /locus_tag="VVO74_000002"
     CDS             1308..2036
                     /locus_tag="VVO74_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5694110.1"
                     /translation="MKLNKFNFIKENIRDLYSSGVIYLGLIISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRIISRDFSHNTISLFYNQQKNRMIYLLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVTSNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            2422..2631
                     /locus_tag="VVO74_000003"
     CDS             2422..2631
                     /locus_tag="VVO74_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5694111.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            2621..3109
                     /locus_tag="VVO74_000004"
     CDS             2621..3109
                     /locus_tag="VVO74_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694112.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            3225..4685
                     /locus_tag="VVO74_000005"
     CDS             3225..4685
                     /locus_tag="VVO74_000005"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU5694113.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISYMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            4682..5506
                     /gene="nadE"
                     /locus_tag="VVO74_000006"
     CDS             4682..5506
                     /gene="nadE"
                     /locus_tag="VVO74_000006"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU5694114.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            5803..6354
                     /locus_tag="VVO74_000007"
     CDS             5803..6354
                     /locus_tag="VVO74_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5694115.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            7068..7761
                     /locus_tag="VVO74_000008"
                     /pseudo
     CDS             7068..7761
                     /locus_tag="VVO74_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            7815..8204
                     /locus_tag="VVO74_000009"
     CDS             7815..8204
                     /locus_tag="VVO74_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU5694116.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(8865..9893)
                     /gene="queA"
                     /locus_tag="VVO74_000010"
     CDS             complement(8865..9893)
                     /gene="queA"
                     /locus_tag="VVO74_000010"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU5694117.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            10044..10751
                     /locus_tag="VVO74_000011"
     CDS             10044..10751
                     /locus_tag="VVO74_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU5694118.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            10829..11338
                     /locus_tag="VVO74_000012"
     CDS             10829..11338
                     /locus_tag="VVO74_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694119.1"
                     /translation="MNKEEFLKIKEAYKSARTEERKSIIGFITKKKDKEGNFLFTKSK
                     DKPYTTRNQYSGGGGNKKYTSGSRLSRPYDLSNHMWIDLSYKGNDILISLQSFDIDPN
                     SKELHVLYDRIGILFEQSKKIPIFKDCYTITKVSDAFLKMETTNWELPLSKADMEEMV
                     NYIINHYEE"
     gene            11418..11594
                     /locus_tag="VVO74_000013"
     CDS             11418..11594
                     /locus_tag="VVO74_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU5694120.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            11724..12659
                     /locus_tag="VVO74_000014"
     CDS             11724..12659
                     /locus_tag="VVO74_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU5694121.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            12652..13440
                     /locus_tag="VVO74_000015"
     CDS             12652..13440
                     /locus_tag="VVO74_000015"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU5694122.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            13441..13824
                     /locus_tag="VVO74_000016"
     CDS             13441..13824
                     /locus_tag="VVO74_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU5694123.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            13840..14229
                     /locus_tag="VVO74_000017"
     CDS             13840..14229
                     /locus_tag="VVO74_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU5694124.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIHITEE"
     gene            14313..15443
                     /locus_tag="VVO74_000018"
     CDS             14313..15443
                     /locus_tag="VVO74_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU5694125.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            15448..16185
                     /locus_tag="VVO74_000019"
     CDS             15448..16185
                     /locus_tag="VVO74_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU5694126.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            16196..16969
                     /locus_tag="VVO74_000020"
     CDS             16196..16969
                     /locus_tag="VVO74_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU5694127.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            16959..17576
                     /locus_tag="VVO74_000021"
     CDS             16959..17576
                     /locus_tag="VVO74_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU5694128.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            17786..18187
                     /locus_tag="VVO74_000022"
     CDS             17786..18187
                     /locus_tag="VVO74_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU5694129.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            18187..18465
                     /locus_tag="VVO74_000023"
     CDS             18187..18465
                     /locus_tag="VVO74_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU5694130.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            18455..19228
                     /locus_tag="VVO74_000024"
     CDS             18455..19228
                     /locus_tag="VVO74_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU5694131.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSSTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRSVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            19229..20533
                     /locus_tag="VVO74_000025"
     CDS             19229..20533
                     /locus_tag="VVO74_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU5694132.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            21107..21985
                     /gene="pstS"
                     /locus_tag="VVO74_000026"
     CDS             21107..21985
                     /gene="pstS"
                     /locus_tag="VVO74_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU5694133.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            21985..22902
                     /gene="pstC"
                     /locus_tag="VVO74_000027"
     CDS             21985..22902
                     /gene="pstC"
                     /locus_tag="VVO74_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU5694134.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            22892..23776
                     /gene="pstA"
                     /locus_tag="VVO74_000028"
     CDS             22892..23776
                     /gene="pstA"
                     /locus_tag="VVO74_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU5694135.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            23787..24590
                     /gene="pstB"
                     /locus_tag="VVO74_000029"
     CDS             23787..24590
                     /gene="pstB"
                     /locus_tag="VVO74_000029"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU5694136.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            24603..25361
                     /gene="pstB"
                     /locus_tag="VVO74_000030"
     CDS             24603..25361
                     /gene="pstB"
                     /locus_tag="VVO74_000030"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU5694137.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            25373..26026
                     /gene="phoU"
                     /locus_tag="VVO74_000031"
     CDS             25373..26026
                     /gene="phoU"
                     /locus_tag="VVO74_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU5694138.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            26183..26998
                     /locus_tag="VVO74_000032"
     CDS             26183..26998
                     /locus_tag="VVO74_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU5694139.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKNEGTYQSYLEKAASLTEVEE"
     gene            complement(27018..28289)
                     /locus_tag="VVO74_000033"
     CDS             complement(27018..28289)
                     /locus_tag="VVO74_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU5694140.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            28431..29162
                     /gene="budA"
                     /locus_tag="VVO74_000034"
     CDS             28431..29162
                     /gene="budA"
                     /locus_tag="VVO74_000034"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU5694141.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            29172..29924
                     /locus_tag="VVO74_000035"
     CDS             29172..29924
                     /locus_tag="VVO74_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEU5694142.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            30036..30986
                     /gene="murB"
                     /locus_tag="VVO74_000036"
     CDS             30036..30986
                     /gene="murB"
                     /locus_tag="VVO74_000036"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU5694143.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            31045..32202
                     /locus_tag="VVO74_000037"
     CDS             31045..32202
                     /locus_tag="VVO74_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694144.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            32183..32989
                     /locus_tag="VVO74_000038"
     CDS             32183..32989
                     /locus_tag="VVO74_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5694145.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            32986..33759
                     /locus_tag="VVO74_000039"
     CDS             32986..33759
                     /locus_tag="VVO74_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5694146.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            33756..34826
                     /locus_tag="VVO74_000040"
     CDS             33756..34826
                     /locus_tag="VVO74_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU5694147.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYEAFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKLEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            35087..35326
                     /locus_tag="VVO74_000041"
     CDS             35087..35326
                     /locus_tag="VVO74_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694148.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLNDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            35601..36086
                     /locus_tag="VVO74_000042"
     CDS             35601..36086
                     /locus_tag="VVO74_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU5694149.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            36108..38726
                     /gene="alaS"
                     /locus_tag="VVO74_000043"
     CDS             36108..38726
                     /gene="alaS"
                     /locus_tag="VVO74_000043"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU5694150.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVDNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAIAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(38816..40270)
                     /locus_tag="VVO74_000044"
     CDS             complement(38816..40270)
                     /locus_tag="VVO74_000044"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU5694151.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANKELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            40449..41198
                     /locus_tag="VVO74_000045"
     CDS             40449..41198
                     /locus_tag="VVO74_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694152.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            41179..42813
                     /locus_tag="VVO74_000046"
     CDS             41179..42813
                     /locus_tag="VVO74_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694153.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLPILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            43498..44661
                     /locus_tag="VVO74_000047"
     CDS             43498..44661
                     /locus_tag="VVO74_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU5694154.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            44658..45335
                     /locus_tag="VVO74_000048"
     CDS             44658..45335
                     /locus_tag="VVO74_000048"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU5694155.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            45325..46179
                     /locus_tag="VVO74_000049"
     CDS             45325..46179
                     /locus_tag="VVO74_000049"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU5694156.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            46198..47265
                     /locus_tag="VVO74_000050"
     CDS             46198..47265
                     /locus_tag="VVO74_000050"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU5694157.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            47275..48441
                     /gene="aroC"
                     /locus_tag="VVO74_000051"
     CDS             47275..48441
                     /gene="aroC"
                     /locus_tag="VVO74_000051"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU5694158.1"
                     /translation="MRYLTAGESHGPRLTAIIDGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            48451..49554
                     /locus_tag="VVO74_000052"
     CDS             48451..49554
                     /locus_tag="VVO74_000052"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU5694159.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSEIILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            49565..49903
                     /locus_tag="VVO74_000053"
     CDS             49565..49903
                     /locus_tag="VVO74_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU5694160.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTDY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            49995..51278
                     /gene="aroA"
                     /locus_tag="VVO74_000054"
     CDS             49995..51278
                     /gene="aroA"
                     /locus_tag="VVO74_000054"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU5694161.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLSPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            51271..51747
                     /locus_tag="VVO74_000055"
     CDS             51271..51747
                     /locus_tag="VVO74_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU5694162.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGESAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIVADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            51744..52592
                     /gene="pheA"
                     /locus_tag="VVO74_000056"
     CDS             51744..52592
                     /gene="pheA"
                     /locus_tag="VVO74_000056"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU5694163.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            52589..53863
                     /gene="psr"
                     /locus_tag="VVO74_000057"
     CDS             52589..53863
                     /gene="psr"
                     /locus_tag="VVO74_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU5694164.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     RNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSSPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            54142..54987
                     /locus_tag="VVO74_000058"
     CDS             54142..54987
                     /locus_tag="VVO74_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU5694165.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSYKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKDPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            54977..56080
                     /locus_tag="VVO74_000059"
     CDS             54977..56080
                     /locus_tag="VVO74_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU5694166.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            56082..57068
                     /locus_tag="VVO74_000060"
     CDS             56082..57068
                     /locus_tag="VVO74_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU5694167.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQIYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            57084..58517
                     /locus_tag="VVO74_000061"
     CDS             57084..58517
                     /locus_tag="VVO74_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU5694168.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFIAKMLTKEN"
     gene            58546..59580
                     /locus_tag="VVO74_000062"
     CDS             58546..59580
                     /locus_tag="VVO74_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU5694169.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            59722..60459
                     /gene="mecA"
                     /locus_tag="VVO74_000063"
     CDS             59722..60459
                     /gene="mecA"
                     /locus_tag="VVO74_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU5694170.1"
                     /translation="MKMKQISDTTLKITISLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFAEDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            60610..61896
                     /locus_tag="VVO74_000064"
     CDS             60610..61896
                     /locus_tag="VVO74_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU5694171.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVVHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            61898..62767
                     /locus_tag="VVO74_000065"
     CDS             61898..62767
                     /locus_tag="VVO74_000065"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU5694172.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            63017..63955
                     /gene="msrB"
                     /locus_tag="VVO74_000066"
     CDS             63017..63955
                     /gene="msrB"
                     /locus_tag="VVO74_000066"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU5694173.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            64013..65737
                     /locus_tag="VVO74_000067"
     CDS             64013..65737
                     /locus_tag="VVO74_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694174.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISTELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISVKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            65739..67490
                     /locus_tag="VVO74_000068"
     CDS             65739..67490
                     /locus_tag="VVO74_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694175.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     TSDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRF
                     YPISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVI
                     AAAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATS
                     SIDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMD
                     RKGKYYQMQKAAAFSSE"
     gene            67837..69096
                     /locus_tag="VVO74_000069"
     CDS             67837..69096
                     /locus_tag="VVO74_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU5694176.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    69172..69307
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            69346..69846
                     /locus_tag="VVO74_000070"
     CDS             69346..69846
                     /locus_tag="VVO74_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU5694177.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            69922..70290
                     /gene="rplL"
                     /locus_tag="VVO74_000071"
     CDS             69922..70290
                     /gene="rplL"
                     /locus_tag="VVO74_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU5694178.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            70477..70647
                     /locus_tag="VVO74_000072"
     CDS             70477..70647
                     /locus_tag="VVO74_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694179.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            70647..70895
                     /locus_tag="VVO74_000073"
                     /pseudo
     CDS             70647..70895
                     /locus_tag="VVO74_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            70909..71249
                     /locus_tag="VVO74_000074"
                     /pseudo
     CDS             70909..71249
                     /locus_tag="VVO74_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            71242..71622
                     /locus_tag="VVO74_000075"
     CDS             71242..71622
                     /locus_tag="VVO74_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU5694180.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            71635..71778
                     /locus_tag="VVO74_000076"
     CDS             71635..71778
                     /locus_tag="VVO74_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694181.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            71871..72458
                     /locus_tag="VVO74_000077"
     CDS             71871..72458
                     /locus_tag="VVO74_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5694182.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWSLLVYSLLLF"
     gene            72660..72797
                     /locus_tag="VVO74_000078"
     CDS             72660..72797
                     /locus_tag="VVO74_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEU5694183.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            73087..74490
                     /locus_tag="VVO74_000079"
     CDS             73087..74490
                     /locus_tag="VVO74_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HEU5694184.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGP
                     YILSDKRWDEAPIYLRYGVFRPSRDDEKKVVIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSSSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYWYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            74679..75297
                     /locus_tag="VVO74_000080"
                     /pseudo
     CDS             74679..75297
                     /locus_tag="VVO74_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            75312..76052
                     /locus_tag="VVO74_000081"
     CDS             75312..76052
                     /locus_tag="VVO74_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694185.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            76055..77374
                     /locus_tag="VVO74_000082"
     CDS             76055..77374
                     /locus_tag="VVO74_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694186.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLGDILIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
     gene            77508..77645
                     /locus_tag="VVO74_000083"
     CDS             77508..77645
                     /locus_tag="VVO74_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEU5694187.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            77941..79292
                     /locus_tag="VVO74_000084"
     CDS             join(77941..78382,78382..79292)
                     /locus_tag="VVO74_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU5694188.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKEIQASMSRKGNSPDNGMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKSFG
                     "
     gene            complement(79527..80135)
                     /locus_tag="VVO74_000085"
     CDS             complement(79527..80135)
                     /locus_tag="VVO74_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEU5694189.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRH
                     IGVIYIILHLIATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            80301..80471
                     /locus_tag="VVO74_000086"
                     /pseudo
     CDS             80301..80471
                     /locus_tag="VVO74_000086"
                     /inference="COORDINATES: protein motif:HMM:NF013577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            80460..81071
                     /locus_tag="VVO74_000087"
     CDS             80460..81071
                     /locus_tag="VVO74_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU5694190.1"
                     /translation="MTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIEL
                     AIKLIREANQILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDL
                     IIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGG
                     SLMAKASQLFIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
     gene            82054..82506
                     /locus_tag="VVO74_000088"
                     /pseudo
     CDS             82054..82506
                     /locus_tag="VVO74_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
     gene            82525..83862
                     /locus_tag="VVO74_000089"
     CDS             82525..83862
                     /locus_tag="VVO74_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU5694191.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            83941..84825
                     /locus_tag="VVO74_000090"
     CDS             83941..84825
                     /locus_tag="VVO74_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU5694192.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            84825..85658
                     /locus_tag="VVO74_000091"
     CDS             84825..85658
                     /locus_tag="VVO74_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU5694193.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLITIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            85677..87770
                     /gene="nanB"
                     /locus_tag="VVO74_000092"
     CDS             85677..87770
                     /gene="nanB"
                     /locus_tag="VVO74_000092"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEU5694194.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            87783..88886
                     /locus_tag="VVO74_000093"
     CDS             87783..88886
                     /locus_tag="VVO74_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU5694195.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            89060..89758
                     /locus_tag="VVO74_000094"
     CDS             89060..89758
                     /locus_tag="VVO74_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU5694196.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            89777..91294
                     /locus_tag="VVO74_000095"
     CDS             89777..91294
                     /locus_tag="VVO74_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU5694197.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            91419..92747
                     /locus_tag="VVO74_000096"
     CDS             91419..92747
                     /locus_tag="VVO74_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5694198.1"
                     /translation="MKFRKLACTVLAGAVVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            92999..93865
                     /locus_tag="VVO74_000097"
     CDS             92999..93865
                     /locus_tag="VVO74_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU5694199.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            93881..94720
                     /locus_tag="VVO74_000098"
     CDS             93881..94720
                     /locus_tag="VVO74_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU5694200.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            94993..95445
                     /locus_tag="VVO74_000099"
     CDS             94993..95445
                     /locus_tag="VVO74_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU5694201.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCYEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            95578..95886
                     /locus_tag="VVO74_000100"
     CDS             95578..95886
                     /locus_tag="VVO74_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694202.1"
                     /translation="MDGQGITVDEMAWIIRGIVNALIGRYIKLGAYAAKYGISMARSI
                     LSRAAATAAARVGLSTKISGWILRVAVNVADVYGNFAYNIAAAWDAHDKIPNNGRINF
                     "
     gene            96170..96814
                     /locus_tag="VVO74_000101"
     CDS             96170..96814
                     /locus_tag="VVO74_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU5694203.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            96983..97900
                     /locus_tag="VVO74_000102"
     CDS             96983..97900
                     /locus_tag="VVO74_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEU5694204.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            97918..98802
                     /locus_tag="VVO74_000103"
     CDS             97918..98802
                     /locus_tag="VVO74_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU5694205.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGLVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASMTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(98818..99669)
                     /locus_tag="VVO74_000104"
     CDS             complement(98818..99669)
                     /locus_tag="VVO74_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU5694206.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKNSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            99869..101926
                     /gene="pbp2b"
                     /locus_tag="VVO74_000105"
     CDS             99869..101926
                     /gene="pbp2b"
                     /locus_tag="VVO74_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEU5694207.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANDGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSELTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            101937..102533
                     /gene="recR"
                     /locus_tag="VVO74_000106"
     CDS             101937..102533
                     /gene="recR"
                     /locus_tag="VVO74_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU5694208.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            102709..103752
                     /locus_tag="VVO74_000107"
     CDS             102709..103752
                     /locus_tag="VVO74_000107"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU5694209.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALELAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            103836..105209
                     /locus_tag="VVO74_000108"
     CDS             103836..105209
                     /locus_tag="VVO74_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU5694210.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLSANDQILLKGSNSMNLAMLVE
                     SLENETK"
     gene            105196..105807
                     /locus_tag="VVO74_000109"
     CDS             105196..105807
                     /locus_tag="VVO74_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU5694211.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGQREQYLD"
     gene            105898..106602
                     /locus_tag="VVO74_000110"
     CDS             105898..106602
                     /locus_tag="VVO74_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU5694212.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            106821..108194
                     /gene="ftsA"
                     /locus_tag="VVO74_000111"
     CDS             106821..108194
                     /gene="ftsA"
                     /locus_tag="VVO74_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU5694213.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRTGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            108211..109470
                     /gene="ftsZ"
                     /locus_tag="VVO74_000112"
     CDS             108211..109470
                     /gene="ftsZ"
                     /locus_tag="VVO74_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU5694214.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETAELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            109475..110146
                     /locus_tag="VVO74_000113"
     CDS             109475..110146
                     /locus_tag="VVO74_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU5694215.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            110156..110695
                     /locus_tag="VVO74_000114"
     CDS             110156..110695
                     /locus_tag="VVO74_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU5694216.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            110695..110958
                     /locus_tag="VVO74_000115"
     CDS             110695..110958
                     /locus_tag="VVO74_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU5694217.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            111015..111740
                     /locus_tag="VVO74_000116"
     CDS             111015..111740
                     /locus_tag="VVO74_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU5694218.1"
                     /translation="MEWIKKVEDSYAPFLTPFINPHQEKLLKILAKTYGLACSSSGEF
                     VSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHLTHAKILGTVINQLGIERKLF
                     GDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEERPFTEKIDKLEQYRELDLSV
                     SSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDKSDYTVQVGDLISVRKFGRLR
                     LLQDKGQTKKEKKKITVQLLLSK"
     gene            111749..112537
                     /gene="divIVA"
                     /locus_tag="VVO74_000117"
     CDS             111749..112537
                     /gene="divIVA"
                     /locus_tag="VVO74_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEU5694219.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPVPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            112885..115677
                     /locus_tag="VVO74_000118"
     CDS             112885..115677
                     /locus_tag="VVO74_000118"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU5694220.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKIIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFADAVAEGFEEK"
     gene            116234..116521
                     /locus_tag="VVO74_000119"
     CDS             116234..116521
                     /locus_tag="VVO74_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694221.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNTLKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLG"
     gene            117131..117823
                     /locus_tag="VVO74_000120"
     CDS             117131..117823
                     /locus_tag="VVO74_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU5694222.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            117876..120287
                     /locus_tag="VVO74_000121"
     CDS             117876..120287
                     /locus_tag="VVO74_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU5694223.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGRI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDEKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            120537..121238
                     /locus_tag="VVO74_000122"
     CDS             120537..121238
                     /locus_tag="VVO74_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694224.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            121240..123948
                     /locus_tag="VVO74_000123"
     CDS             121240..123948
                     /locus_tag="VVO74_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU5694225.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGCFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NVFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLAFVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKAL
                     YKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(124044..124535)
                     /gene="tpx"
                     /locus_tag="VVO74_000124"
     CDS             complement(124044..124535)
                     /gene="tpx"
                     /locus_tag="VVO74_000124"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU5694226.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(124658..125587)
                     /gene="psaA"
                     /locus_tag="VVO74_000125"
     CDS             complement(124658..125587)
                     /gene="psaA"
                     /locus_tag="VVO74_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU5694227.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKATTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(125619..126467)
                     /locus_tag="VVO74_000126"
     CDS             complement(125619..126467)
                     /locus_tag="VVO74_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU5694228.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(126464..127186)
                     /locus_tag="VVO74_000127"
     CDS             complement(126464..127186)
                     /locus_tag="VVO74_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU5694229.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            127477..129369
                     /gene="pepO"
                     /locus_tag="VVO74_000128"
     CDS             127477..129369
                     /gene="pepO"
                     /locus_tag="VVO74_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU5694230.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVATVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(129492..130121)
                     /locus_tag="VVO74_000129"
     CDS             complement(129492..130121)
                     /locus_tag="VVO74_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU5694231.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            131117..133339
                     /locus_tag="VVO74_000130"
     CDS             131117..133339
                     /locus_tag="VVO74_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU5694232.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMDQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            133369..133812
                     /locus_tag="VVO74_000131"
     CDS             133369..133812
                     /locus_tag="VVO74_000131"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU5694233.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGVAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGANMQVELVNNGPVTIILDTKKR"
     gene            complement(133851..134266)
                     /locus_tag="VVO74_000132"
                     /pseudo
     CDS             complement(133851..134266)
                     /locus_tag="VVO74_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            134626..134988
                     /locus_tag="VVO74_000133"
     CDS             134626..134988
                     /locus_tag="VVO74_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694234.1"
                     /translation="MRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVREYVPKKE
                     RIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEEDVLILLSELQNFFLDVFQAKRIHRA
                     FCVRLCLKAQFLLSNNDS"
     gene            135169..135468
                     /locus_tag="VVO74_000134"
     CDS             135169..135468
                     /locus_tag="VVO74_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694235.1"
                     /translation="MNRDVLEFLRTETAEKISLYISEANRLEGDVTLLAPSSQDLEDI
                     KNAMLSNSNLGLKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(135563..136000)
                     /locus_tag="VVO74_000135"
     CDS             complement(135563..136000)
                     /locus_tag="VVO74_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694236.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLGENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(136102..136767)
                     /locus_tag="VVO74_000136"
     CDS             complement(136102..136767)
                     /locus_tag="VVO74_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEU5694237.1"
                     /translation="MAIASGYLNSRLDKFVDWGPWTALVPFGLISVTNVGISMLSTRF
                     TGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQEGRPN
                     QMSQKQVKLAAIIISIIAFLFAFVTNYIGYEGKMNLLAYVTTIAFALSLIANALNALK
                     LTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVRYIEGNSN
                     KEY"
     gene            complement(136955..137605)
                     /locus_tag="VVO74_000137"
     CDS             complement(136955..137605)
                     /locus_tag="VVO74_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU5694238.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            137717..138559
                     /locus_tag="VVO74_000138"
     CDS             137717..138559
                     /locus_tag="VVO74_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU5694239.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQENFDRLVTHPPCDIAVY
                     GHIHQQLLRHGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDGKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            138635..139072
                     /locus_tag="VVO74_000139"
     CDS             138635..139072
                     /locus_tag="VVO74_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU5694240.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            139141..139443
                     /locus_tag="VVO74_000140"
     CDS             139141..139443
                     /locus_tag="VVO74_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694241.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFTFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(139534..140607)
                     /locus_tag="VVO74_000141"
     CDS             complement(139534..140607)
                     /locus_tag="VVO74_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU5694242.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            140763..141440
                     /locus_tag="VVO74_000142"
     CDS             140763..141440
                     /locus_tag="VVO74_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5694243.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            141433..142407
                     /locus_tag="VVO74_000143"
     CDS             141433..142407
                     /locus_tag="VVO74_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU5694244.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLFLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(142456..144399)
                     /gene="thrS"
                     /locus_tag="VVO74_000144"
     CDS             complement(142456..144399)
                     /gene="thrS"
                     /locus_tag="VVO74_000144"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU5694245.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNIAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVNYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(144457..144780)
                     /locus_tag="VVO74_000145"
     CDS             complement(144457..144780)
                     /locus_tag="VVO74_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU5694246.1"
                     /translation="MELQELVEHSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            145645..146190
                     /locus_tag="VVO74_000146"
     CDS             145645..146190
                     /locus_tag="VVO74_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU5694247.1"
                     /translation="MKLAVIAANGQVGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAES
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKRNKPD"
     gene            146416..146685
                     /gene="rpsO"
                     /locus_tag="VVO74_000147"
     CDS             146416..146685
                     /gene="rpsO"
                     /locus_tag="VVO74_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU5694248.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            147501..148115
                     /locus_tag="VVO74_000148"
     CDS             147501..148115
                     /locus_tag="VVO74_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU5694249.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(148408..149157)
                     /locus_tag="VVO74_000149"
     CDS             complement(148408..149157)
                     /locus_tag="VVO74_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU5694250.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMILKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            149290..151626
                     /locus_tag="VVO74_000150"
     CDS             149290..151626
                     /locus_tag="VVO74_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEU5694251.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQAKK"
     gene            151727..152404
                     /locus_tag="VVO74_000151"
     CDS             151727..152404
                     /locus_tag="VVO74_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU5694252.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVPHVSK"
     gene            152391..153188
                     /locus_tag="VVO74_000152"
     CDS             152391..153188
                     /locus_tag="VVO74_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU5694253.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            153205..154308
                     /locus_tag="VVO74_000153"
     CDS             153205..154308
                     /locus_tag="VVO74_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU5694254.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWLSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLSILDQAPANELFPGLQGFDNLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            154315..154506
                     /locus_tag="VVO74_000154"
     CDS             154315..154506
                     /locus_tag="VVO74_000154"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694255.1"
                     /translation="MKIKEQTRKLAADYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            154609..155628
                     /gene="galE"
                     /locus_tag="VVO74_000155"
     CDS             154609..155628
                     /gene="galE"
                     /locus_tag="VVO74_000155"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU5694256.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGIIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            155630..156595
                     /locus_tag="VVO74_000156"
     CDS             155630..156595
                     /locus_tag="VVO74_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU5694257.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(156646..156852)
                     /locus_tag="VVO74_000157"
     CDS             complement(156646..156852)
                     /locus_tag="VVO74_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU5694258.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            156904..157380
                     /locus_tag="VVO74_000158"
     CDS             156904..157380
                     /locus_tag="VVO74_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU5694259.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            157389..158060
                     /locus_tag="VVO74_000159"
     CDS             157389..158060
                     /locus_tag="VVO74_000159"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU5694260.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            158190..158528
                     /locus_tag="VVO74_000160"
     CDS             158190..158528
                     /locus_tag="VVO74_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU5694261.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIHIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            158531..159160
                     /locus_tag="VVO74_000161"
     CDS             158531..159160
                     /locus_tag="VVO74_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU5694262.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            159400..160551
                     /locus_tag="VVO74_000162"
     CDS             159400..160551
                     /locus_tag="VVO74_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU5694263.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGARLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            160869..161618
                     /gene="truA"
                     /locus_tag="VVO74_000163"
     CDS             160869..161618
                     /gene="truA"
                     /locus_tag="VVO74_000163"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU5694264.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQIDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            161608..162381
                     /locus_tag="VVO74_000164"
     CDS             161608..162381
                     /locus_tag="VVO74_000164"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU5694265.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            162359..162820
                     /locus_tag="VVO74_000165"
     CDS             162359..162820
                     /locus_tag="VVO74_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU5694266.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            complement(163079..163282)
                     /locus_tag="VVO74_000166"
     CDS             complement(163079..163282)
                     /locus_tag="VVO74_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5694267.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(163275..164357)
                     /locus_tag="VVO74_000167"
     CDS             complement(163275..164357)
                     /locus_tag="VVO74_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU5694268.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(164483..165265)
                     /locus_tag="VVO74_000168"
     CDS             complement(164483..165265)
                     /locus_tag="VVO74_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU5694269.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(165265..166608)
                     /locus_tag="VVO74_000169"
     CDS             complement(165265..166608)
                     /locus_tag="VVO74_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU5694270.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGTYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(166707..168023)
                     /locus_tag="VVO74_000170"
     CDS             complement(166707..168023)
                     /locus_tag="VVO74_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU5694271.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQNLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDINGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            168216..169442
                     /locus_tag="VVO74_000171"
     CDS             168216..169442
                     /locus_tag="VVO74_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEU5694272.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            169641..171215
                     /locus_tag="VVO74_000172"
     CDS             169641..171215
                     /locus_tag="VVO74_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU5694273.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            171479..172267
                     /gene="codY"
                     /locus_tag="VVO74_000173"
     CDS             171479..172267
                     /gene="codY"
                     /locus_tag="VVO74_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU5694274.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            172267..172842
                     /locus_tag="VVO74_000174"
     CDS             172267..172842
                     /locus_tag="VVO74_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU5694275.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            172924..173009
                     /locus_tag="VVO74_000175"
     tRNA            172924..173009
                     /locus_tag="VVO74_000175"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:172958..172960,aa:Leu,seq:aag)
     gene            173292..174422
                     /gene="ugpC"
                     /locus_tag="VVO74_000176"
     CDS             173292..174422
                     /gene="ugpC"
                     /locus_tag="VVO74_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU5694276.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(174544..174714)
                     /locus_tag="VVO74_000177"
     CDS             complement(174544..174714)
                     /locus_tag="VVO74_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694277.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEYKEHHNIDA"
     gene            174921..175679
                     /locus_tag="VVO74_000178"
     CDS             174921..175679
                     /locus_tag="VVO74_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU5694278.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            175767..176279
                     /locus_tag="VVO74_000179"
     CDS             175767..176279
                     /locus_tag="VVO74_000179"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU5694279.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            176461..177405
                     /locus_tag="VVO74_000180"
     CDS             176461..177405
                     /locus_tag="VVO74_000180"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU5694280.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            177414..178091
                     /locus_tag="VVO74_000181"
     CDS             177414..178091
                     /locus_tag="VVO74_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU5694281.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            178189..178947
                     /locus_tag="VVO74_000182"
     CDS             178189..178947
                     /locus_tag="VVO74_000182"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU5694282.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            178985..180490
                     /gene="lytC"
                     /locus_tag="VVO74_000183"
     CDS             178985..180490
                     /gene="lytC"
                     /locus_tag="VVO74_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEU5694283.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRNGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            180986..181504
                     /locus_tag="VVO74_000184"
     CDS             180986..181504
                     /locus_tag="VVO74_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU5694284.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            181634..182140
                     /locus_tag="VVO74_000185"
     CDS             181634..182140
                     /locus_tag="VVO74_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU5694285.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            182140..182310
                     /locus_tag="VVO74_000186"
     CDS             182140..182310
                     /locus_tag="VVO74_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694286.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            182342..183574
                     /gene="clpX"
                     /locus_tag="VVO74_000187"
     CDS             182342..183574
                     /gene="clpX"
                     /locus_tag="VVO74_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU5694287.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            183583..184170
                     /locus_tag="VVO74_000188"
     CDS             183583..184170
                     /locus_tag="VVO74_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU5694288.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            184181..184561
                     /locus_tag="VVO74_000189"
     CDS             184181..184561
                     /locus_tag="VVO74_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU5694289.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            184613..185503
                     /gene="rapZ"
                     /locus_tag="VVO74_000190"
     CDS             184613..185503
                     /gene="rapZ"
                     /locus_tag="VVO74_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU5694290.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            185500..186477
                     /locus_tag="VVO74_000191"
     CDS             185500..186477
                     /locus_tag="VVO74_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU5694291.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDFRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            186474..187385
                     /gene="whiA"
                     /locus_tag="VVO74_000192"
     CDS             186474..187385
                     /gene="whiA"
                     /locus_tag="VVO74_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU5694292.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(187419..188387)
                     /locus_tag="VVO74_000193"
     CDS             complement(187419..188387)
                     /locus_tag="VVO74_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU5694293.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELESVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            188523..189380
                     /locus_tag="VVO74_000194"
     CDS             188523..189380
                     /locus_tag="VVO74_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU5694294.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYMSTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            189367..190146
                     /locus_tag="VVO74_000195"
     CDS             189367..190146
                     /locus_tag="VVO74_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEU5694295.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            190170..191522
                     /locus_tag="VVO74_000196"
     CDS             190170..191522
                     /locus_tag="VVO74_000196"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU5694296.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGNIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            191596..191970
                     /locus_tag="VVO74_000197"
     CDS             191596..191970
                     /locus_tag="VVO74_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU5694297.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            191972..192820
                     /locus_tag="VVO74_000198"
     CDS             191972..192820
                     /locus_tag="VVO74_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU5694298.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            193097..193864
                     /locus_tag="VVO74_000199"
     CDS             193097..193864
                     /locus_tag="VVO74_000199"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU5694299.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMHIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            193876..195060
                     /locus_tag="VVO74_000200"
     CDS             193876..195060
                     /locus_tag="VVO74_000200"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU5694300.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHNPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            195057..196928
                     /locus_tag="VVO74_000201"
     CDS             195057..196928
                     /locus_tag="VVO74_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU5694301.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(197071..198255)
                     /gene="mntE"
                     /locus_tag="VVO74_000202"
     CDS             complement(197071..198255)
                     /gene="mntE"
                     /locus_tag="VVO74_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU5694302.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLATGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            198559..201255
                     /locus_tag="VVO74_000203"
     CDS             198559..201255
                     /locus_tag="VVO74_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU5694303.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            201268..202059
                     /gene="yghU"
                     /locus_tag="VVO74_000204"
     CDS             201268..202059
                     /gene="yghU"
                     /locus_tag="VVO74_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEU5694304.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRQTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QENLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            202175..202585
                     /locus_tag="VVO74_000205"
     CDS             202175..202585
                     /locus_tag="VVO74_000205"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU5694305.1"
                     /translation="MEKKIVKDNLFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            202597..204192
                     /locus_tag="VVO74_000206"
     CDS             202597..204192
                     /locus_tag="VVO74_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694306.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            204259..204423
                     /locus_tag="VVO74_000207"
     CDS             204259..204423
                     /locus_tag="VVO74_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU5694307.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            204502..205230
                     /gene="yaaA"
                     /locus_tag="VVO74_000208"
     CDS             204502..205230
                     /gene="yaaA"
                     /locus_tag="VVO74_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU5694308.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(205508..206056)
                     /locus_tag="VVO74_000209"
     CDS             complement(205508..206056)
                     /locus_tag="VVO74_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU5694309.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALASKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            206377..206886
                     /locus_tag="VVO74_000210"
     CDS             206377..206886
                     /locus_tag="VVO74_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU5694310.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GLWNYPTVF"
     gene            206862..208049
                     /locus_tag="VVO74_000211"
     CDS             206862..208049
                     /locus_tag="VVO74_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU5694311.1"
                     /translation="MELSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            208042..208407
                     /locus_tag="VVO74_000212"
     CDS             208042..208407
                     /locus_tag="VVO74_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU5694312.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFVIDLDGNNIEVVCHKE"
     gene            208423..209769
                     /gene="asnS"
                     /locus_tag="VVO74_000213"
     CDS             208423..209769
                     /gene="asnS"
                     /locus_tag="VVO74_000213"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU5694313.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            209922..210212
                     /locus_tag="VVO74_000214"
     CDS             209922..210212
                     /locus_tag="VVO74_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU5694314.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            210224..210694
                     /gene="ssbA"
                     /locus_tag="VVO74_000215"
     CDS             210224..210694
                     /gene="ssbA"
                     /locus_tag="VVO74_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU5694315.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            210726..210965
                     /locus_tag="VVO74_000216"
     CDS             210726..210965
                     /locus_tag="VVO74_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU5694316.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            211260..212660
                     /locus_tag="VVO74_000217"
     CDS             211260..212660
                     /locus_tag="VVO74_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU5694317.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            212662..213021
                     /locus_tag="VVO74_000218"
     CDS             212662..213021
                     /locus_tag="VVO74_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU5694318.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            213075..213824
                     /locus_tag="VVO74_000219"
     CDS             213075..213824
                     /locus_tag="VVO74_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU5694319.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVNPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            213814..214113
                     /locus_tag="VVO74_000220"
     CDS             213814..214113
                     /locus_tag="VVO74_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU5694320.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            214184..215119
                     /locus_tag="VVO74_000221"
     CDS             214184..215119
                     /locus_tag="VVO74_000221"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU5694321.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            215205..215717
                     /locus_tag="VVO74_000222"
     CDS             215205..215717
                     /locus_tag="VVO74_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU5694322.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAPGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            215742..216350
                     /locus_tag="VVO74_000223"
     CDS             215742..216350
                     /locus_tag="VVO74_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEU5694323.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            216451..216648
                     /locus_tag="VVO74_000224"
     CDS             216451..216648
                     /locus_tag="VVO74_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU5694324.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(216691..218136)
                     /locus_tag="VVO74_000225"
     CDS             complement(216691..218136)
                     /locus_tag="VVO74_000225"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU5694325.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQSYLVRRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            218242..219864
                     /locus_tag="VVO74_000226"
     CDS             218242..219864
                     /locus_tag="VVO74_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU5694326.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEDSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            220067..222025
                     /locus_tag="VVO74_000227"
     CDS             220067..222025
                     /locus_tag="VVO74_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5694327.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFSVKNGGVLQNLGLDPGEANDKAKAVGLDTYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            222197..223132
                     /locus_tag="VVO74_000228"
     CDS             222197..223132
                     /locus_tag="VVO74_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694328.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFE"
     gene            223157..223879
                     /locus_tag="VVO74_000229"
     CDS             223157..223879
                     /locus_tag="VVO74_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694329.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPSGSGKSTIV
                     RLLEQFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEIL
                     IFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDCIFFLEEGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            224036..225130
                     /locus_tag="VVO74_000230"
     CDS             224036..225130
                     /locus_tag="VVO74_000230"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU5694330.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLATIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            225138..226304
                     /locus_tag="VVO74_000231"
     CDS             225138..226304
                     /locus_tag="VVO74_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU5694331.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQVVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGDAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            226397..229495
                     /locus_tag="VVO74_000232"
     CDS             226397..229495
                     /locus_tag="VVO74_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU5694332.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIVQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLTYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVTVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            229543..230160
                     /locus_tag="VVO74_000233"
     CDS             229543..230160
                     /locus_tag="VVO74_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU5694333.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            230171..231505
                     /locus_tag="VVO74_000234"
     CDS             230171..231505
                     /locus_tag="VVO74_000234"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU5694334.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            231515..231979
                     /locus_tag="VVO74_000235"
     CDS             231515..231979
                     /locus_tag="VVO74_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5694335.1"
                     /translation="MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEEILLYATSQGYSMIWFNPFYLEEQ"
     gene            231976..232470
                     /locus_tag="VVO74_000236"
     CDS             231976..232470
                     /locus_tag="VVO74_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5694336.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            232551..234206
                     /gene="mltG"
                     /locus_tag="VVO74_000237"
     CDS             232551..234206
                     /gene="mltG"
                     /locus_tag="VVO74_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU5694337.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            234277..234759
                     /gene="greA"
                     /locus_tag="VVO74_000238"
     CDS             234277..234759
                     /gene="greA"
                     /locus_tag="VVO74_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU5694338.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT        70091 a        42735 c        52467 g        69615 t
ORIGIN      
        1 gctcttaaag aggggcttat caatctttat aaggaagatg gaaccagcgt cacagttcgt
       61 gcttaatgta gttgtttagt tttaaaaaat tatgcaaagc tccatataca acacttaaac
      121 gagattaaag aatggcgaaa tcccctgatg cgcaagagat tagctgtctt ttttattttt
      181 taagtgataa agtcggagct taggtatcaa agcctatcaa attaaacaaa gaagcgatgt
      241 cttagatatt ttgaaaaaaa ttaataagca gaaaactctc tattattttg ttgtatagag
      301 ttttttgtta ataaaatttc acaaaatgac atttatatat tgcattaagt tagatatatg
      361 atataatatt gttaaaaaga ggcgcaactt tttaaaatta atgagaatca aagagaaaac
      421 caataatatt aatggaggaa taaaaaatgt aagttataaa tgtaagtaag cattatggtc
      481 attcaatcat tctcaaagac ataaattttg cacttaacaa gggtgaaatt gttggtcaag
      541 tagggagaaa tggagttggt aagagtacgt tgatgaaaat tcttgttcag aataatcaac
      601 cgacttcagg taatattata agcagtgata atgttgggta tttaatcgaa gaaccaaaat
      661 tatttttatc taaaacaggt ttagagaatt taaaatattt gtcaaattta tatggtgttg
      721 actacaatca agaaagattt agaagtttga tccaagagtt agatttgact cagtctatta
      781 ataaaaaagt aaagacctat tctttgggta caaaacaaaa attagctttg cttctaactc
      841 tcgttacgga acctgatata ttgattttag atgaaccgac taatggttta gatattgaat
      901 catcacaaat agttttatcg gttctaaaaa atttagcttt acatgaaaat gtgggaattt
      961 taatatcgag tcataaatta gaagatattg aagaaatttg tgagagggtt cttttcttgg
     1021 agaacgggct tttgacattt caaaaagtag gaaaagatag tcataatttc ttgtttgaga
     1081 tagctttttc atcagctaca gatagagaca ttttcattac caaacaagaa tttggggata
     1141 ttgttcagga agagggactg agaattacta tgtctgggaa tattcaaagt agtgagcttt
     1201 ttaaattttt taacgaaaac tctattaaag tagttgattt tgaaactaaa aaagagatgc
     1261 ttaaagatat ttatctaaat cgttcaaaat aaaggaaggt tataatcatg aaattaaata
     1321 aatttaattt tattaaggaa aatataaggg atttatattc atcaggcgta atatatctcg
     1381 gtttgattat ctcgtttata ccgccgatat tgcttacatt ctttattcta aagactcaag
     1441 ggacatcgct tggtattaag catatttcaa acttttatgc tatgctcggt atgttaatgg
     1501 ctgttataca tgctaaccga attattagca gggatttttc ccacaatacg atcagtttat
     1561 tttataatca acagaaaaat cggatgattt acctcttgtc taattttcta tatgccatct
     1621 cagtttccat tatttatgct ttgaatggca ttgtgttact agtcatagta agtaaattgg
     1681 gtattccagg tgatttagga ttagatttta tagtagctat tgtagtcaat acaattttgt
     1741 tagtcctgtt ttattttcta ttatcttaca ttttctattt atacaaattg aaaagtggct
     1801 tggtatttgg tattttagta gctttactac tctttatccc taatatatta aatacgatga
     1861 tgatgaatac tagtaatgat ttgtttatca aagcaattga acttcttcct ttttattctt
     1921 tacctgtatt tgtgacttca aatacgatgt ctattagtca gtatcttgtg gtaatcacta
     1981 caatcatttt attgtacttt ttcactctca agaaaagcaa gaagtattca ttttagtttc
     2041 atttagtatt attttgcata cctaaaatac aataaaaaaa tcagtcatct tggtatgctc
     2101 ctgctttcac tattcaacac gtttttgact tatactaggc tcatttccaa aagcattata
     2161 taatagtgat atgaaaccaa ctaaactaaa caagaaatat aagcaataaa aactcgttta
     2221 aaagattcta ctaaagctaa tactaaataa aaataaaaga gtaaactagg aagtttattt
     2281 caaacaacct aaaatactga ttttcggctg aagataatac tggagtgcaa attaatgggg
     2341 ttataataaa tagctgatag cttgtgttgg ttttggattt tttaagagta gatgagtatt
     2401 aaaactataa ggaggacgaa ggtggctaaa aatttaaaat taaaattagc tcgggtagag
     2461 cgtgatttaa cacaaggtca actggcagag gctgtcgggg tgacacgcca gactattggt
     2521 ttgatagagg cgggaaaata caatcccagt ctctcgctct gccagtctat ttgcagatgt
     2581 ttagggaaaa ccctagacca actattttgg gaggaagaag atgaaaaata gattttatta
     2641 ttatcaatta ctagacgaaa gagaagaaca actgttcaat aaagcgggct ctgaaagttt
     2701 ctatatctgc attgctttgt cgctcctatc ttatatcatt tcagtattag caccaagcct
     2761 ttttaattct aatatgctgc taatcgttat catcataggg acattttact ttttcaatcg
     2821 tgcccgttat ctgggagtga cctactatag tcgttttcat tttacgattt tgggttgttt
     2881 tttcctaacc ttggctatta cggctctttt gatgttgcag aattatcaat tcaacataga
     2941 aatttatcag cacaatcctt tgaattttaa atacctgtct gcttgggtca ttacttatgt
     3001 catttacctt ccgtgggtct ttattggcaa tcttggtctt aagagctatg gcgaatgggc
     3061 tcagaaaaaa tttgaacaag atatggatga attggagagt ggagaatagc ttgttactct
     3121 tttctcaatc cagctaaaat gtgatataat agtattaatt tattggaata catgaaagtt
     3181 cttgaaaatt ttcatgggtt tctagctaag gaagtaggaa aagtatgtat ccagatgata
     3241 gtttgacatt gcacacggac ttgtaccaga tcaacatgat gcaggtttac tttgaccaag
     3301 ggattcacaa taagaaggcg gtctttgagg tgtatttccg ccaacagcct tttaagaacg
     3361 gctatgcggt ttttgcaggt ttggaaagaa ttgtgaacta tcttgaagac ttgcgttttt
     3421 cagatagtga tatagcctat ttggagtcgc ttggttatca tggggcgttc ttggattacc
     3481 ttcgcaattt caagttggag ttgaccgttc gttctgccca agaaggggat ttggtttttg
     3541 ctaatgaacc gattgtgcag gtggaaggac ctctagccca atgtcagttg gtcgaaacgg
     3601 ctcttttgaa catcgtcaac taccagacct tggtggcgac gaaggcagct cgtattcgtt
     3661 cggttatcga agatgaaccc ttgatggagt ttgggacacg tcgggctcaa gaaatggatg
     3721 cggccatctg gggaacacgc gcagctgtga ttggtggcgc caatggaacc agcaacgtgc
     3781 gtgcgggtaa gctctttgac attcctgttt tgggaaccca tgcccatgcc ttggtacagg
     3841 tttatggaaa tgactatgaa gctttcaagg cttacgctgc gacccacaaa aattgtgtct
     3901 ttcttgtgga tacctatgac acccttcgca tcggtgtacc agctgccatt caggtggcgc
     3961 gtgagctggg tgatcagatt aactttatgg gtgtgcggat tgactctggg gatattgcct
     4021 acatttctaa gaaagtccgt cagcaactgg acgaggctgg atttacagag gctaagattt
     4081 atgcttctaa tgatttggac gaaaatacta tcctcaacct caagatgcaa aaggccaaga
     4141 ttgatgtctg gggcgtgggt accaagctga ttacagcata tgaccagcca gctcttgggg
     4201 cggtttacaa gattgttgca atcgaagatg aaactggtca gatgcgcaat acgattaagc
     4261 tgtctaataa tgctgaaaaa gtctctacgc caggtaagaa gcaggtgtgg cgcattacca
     4321 gtcgtgaaaa aggtaagtca gaaggtgact acatcactta tgatggtgtg gatattagct
     4381 acatgacaga aatcaagatg ttccatccga cctatacata catcaagaag acggttcgta
     4441 attttgatgc cgttcctctc ttggtggata tcttcaaaga aggaatatta gtttacaact
     4501 tgcctagttt gactgacatt caggattatg cccgtaaaga atttgacaag ttgtgggatg
     4561 agtataagcg tgtgctcaat ccgcagcact atccagtgga tttggcgcgt gatgtatggc
     4621 aagataagat ggacttgatt gataagatgc gcaaggaagc ccttggtgaa ggagaagaag
     4681 aatgagtttg caagaaacga ttatccaaga gctgggtgtc aaaccagtga ttgatgccca
     4741 ggaagaaatc cgtcgttcta ttgatttctt aaaaagatat ctgaaaaaac atcccttcct
     4801 aaaaaccttt gtactaggga tttctggggg acaagactca accttggcag ggcgtttggc
     4861 gcaattagct atggaagaac tgcgagctga aacgggagac gacagctaca aatttatcgc
     4921 tgtccgcctg ccatacggag tgcaagctga tgaagcagat gctcaaaaag ccctagcctt
     4981 catccagcca gatgtcagct tggttgtgaa tatcaaggaa tcagctgatg ccatgacagc
     5041 tgcagttgaa gcgacaggta gtcctgtttc agacttcaac aaggggaata tcaaggcacg
     5101 ttgccgtatg attgctcagt atgcccttgc tggttcccat agcggagcgg tcattggaac
     5161 agaccacgcc gcggaaaata tcacaggttt ctttaccaag tttggtgacg gcggtgcgga
     5221 tattctccct ctttaccgcc tcaataaacg ccaaggaaaa cagctcttgc agaaacttgg
     5281 cgcagagcca gccctttatg aaaaaatccc aacggcagac ctagaagaag ataaaccagg
     5341 cctagctgac gaagtcgcac ttggagtcac ctatgcagag attgacgatt acctagaagg
     5401 caaaacaatc agcccagaag ctcaagcgac cattgaaaac tggtggcaca aaggccaaca
     5461 caaacgccac ttacccatca ccgtatttga tgacttttgg gagtaaaaac ctccattgga
     5521 ggtttttacc ctgagcctag aaatgagaaa gtgagagaag gtccggggga tcttgaaccc
     5581 cgagtttaga aataagaaaa tgaggcagat tcggtaactc gaagagttcg atttcatcgt
     5641 cttacccctg caacgatgac taggtttgaa aaagcttgct agatcgcatt tcaaaccagg
     5701 cagcgactgc gtcaagaaat tagaagacaa actcgttttc tagctgttac tgagttgagt
     5761 ctttttacta cgagcataga aataaggaag tgaggtagca tcatgaaatc tatcggtacg
     5821 caaatattac agacagaacg tttgatttta agaagatttg tggagagtga tgcagaagcc
     5881 atgtttcaaa attgggcttc atccgctgag aatttgacct atgttacctg ggatccccat
     5941 cctgatgtcg aaatcactcg aaactcgatt cgcaattggg ttgcttccta tactaatctc
     6001 aactattaca aatgggccat ttgtctaaaa gaaaacccag agcaagtgat aggagatatc
     6061 agcatcgtta agatagacga ggctgattta agctgtgaaa tcggctatgt gctaggcaag
     6121 gcttactggg gacatggtat gatgacagag gccttgaaag ctgtcttgga cttttgtttt
     6181 actcaagcag gttttcaaaa ggtcagagca cgttatgcca gtctcaaccc agcttcaggt
     6241 cgtgtcatgg aaaaggctgg aatgtcctat ctacaaacca ttgttaatgg tgtagagaga
     6301 aaaggctatc ttgcggatct tatttattat ggtataagta gggaagaatg ttgaattcta
     6361 ttttctgttt ctatcgaagt caactattta ttgtaaatat aataattagc attccaagtt
     6421 tatttgaaac tttaaaatag catattgatt agtacaagac agatgttcta gttccttctt
     6481 taatctggtt tagtattagt taaaaaatcg cttgaagctt gtaactaaga gggagctaat
     6541 cgactaggtt ctccagccga acaggtggta atgtactttt tatagtgtaa tcctagctgt
     6601 tgttaaattt aaaatagaat cctctatcga gttagggaat taaattcaac caattttatt
     6661 tatgtttttc tatcaaatta tctaatatta aaatagtctc attctgatga gaaaactatt
     6721 ctatttatac tgcatagttg tataaggaat gatgaaagat gagtgaaagt tatcaagttg
     6781 gaatgtttgt atctaaatat attagcatgt atttagataa gatgtctgca atcctttata
     6841 tatgagattg attacgatat agttaaagtg ttagttcaat aatcaatata tcattctaag
     6901 tctattttat atataaagta tattgtttaa cgtttgatag aaaagatgct atactagaag
     6961 taggatgtaa tggcaaaatc taatactaat aagcgctatg caatacgtaa actcggaaag
     7021 atttttggtt ctgcggtaat cgggctaact ttatttttag gaggaatctg aatacaagtt
     7081 ttgttcatgc tgctgatggg attcaatatg tcagagatga tactagagat aaagaagagg
     7141 gaatagagta tgatgacgct gacaatgggg atattattgt aaaagtagcg actaaaccta
     7201 aggtagtaac caagaaaatt tcaagtacgc gaattcgtta tgaaaaagat gaaacaaaag
     7261 accgtagtga aaatcctgtt acaattgatg gagaggatgg ctatgtaact acgacaagga
     7321 cctacgatgt taatccagag actggttatg ttaccgaaca ggttactgtt gatagaaaag
     7381 aagccacgga tacagttatc aaagttccag ctaaaagcaa ggttgaagaa gttcttgttc
     7441 catttgctac taaatatgaa gcagacaatg acctttctgc aggacaggag caagagatta
     7501 ctctaggaaa gaatgggaaa acagttacaa cgataactta taatgtagat ggaaagagtg
     7561 gacaagtaac tgagagtact ttaagtcaaa aaaaaagact ctcaaacaag agttgttaaa
     7621 aaaggaacca agccccaagt tcttgtccaa gaaattccaa tcgaaacaaa atatctcgat
     7681 ggcccaactc ttgataaaag tcaagaagta gaagaagtag gagaaattgg taaattactc
     7741 ttactacaat ctatactgta gatgaacgtg atggaacaat tgaagaaact acttctcgtc
     7801 aaattactaa agagatggta aaaagacgta taaggagagg gacgagagaa cctgaaaaag
     7861 ttgttgttcc tgagcaatca tctattcctt cgtatcctgt atctgttaca tctaaccaag
     7921 gaacagatgt agcagtagaa ccagctaaag cagttgctcc aacaacagac tggaaacaag
     7981 aaaatggtat gtggtatttt tataatactg atggttccat ggcaacaggt tgggtacaag
     8041 ttaatggttc atggtactac ctcaacagca acggttctat gaaagtcaat caatggttcc
     8101 aagttggtgg taaatggtat tatgtaaatg catcgggtga gttagcggtc aatacaagta
     8161 tagatggcta tagagtcaat gataatggtg aatgggtgcg ttaacagatt cctccctgcg
     8221 acaaaattga taatagtatg tctgaatata taattatata taaaaagcta tagataaggt
     8281 catcttatag cgactataaa aaagtgaaca agcctagtct tctgtacatt agaattcaga
     8341 tttgttcact ttttgtttaa tactcaatga aaatcaaaga gcaaactaga aaactagtcg
     8401 caggttgctc aaagtactgc tttgaggttg tagatagaac tgacgaagtc agtcacatat
     8461 ataatccaag gtgacgttga cgcggtttga agagattttt gaagagtata agtctttgat
     8521 tttgagacta aggagagtca gggtcaaagt agtgaatgat tctgaaataa ctcataatag
     8581 tctcttgaga ggacagataa gagtaacaaa tatggtgcta ctcatgtgtc ttgcattttg
     8641 atttacaaac agcgaagaaa atataggaag ctgaaataaa atatagatga atcaatttgg
     8701 agagtcaacg caatctatgg caatattttc gaagctaggg ggaagcattt taatttcaat
     8761 gtactaggcc tcttctacag ctagctagag tttcaattgt agatgttctt tgaaataata
     8821 tcttagcgat ttattggtat tagaagattt agagaaattc tttctcaata aataaacatg
     8881 gcgtcaccaa aactgaagaa gcggtagtgt tcttggatgg catggtggta ggcatctaag
     8941 actaattcac ggcctgcaaa ggcagaaacc aacatgacca gagttgattt tggcaggtgg
     9001 aagttggttg agaaggcatc cacgaccttc cactcatacc caggtttgat aaagatattg
     9061 gtccaaccag aatctgcttg gatttgccca tcaaacttgg aaccaatagt ttccaaggtg
     9121 cggatagaag tggttccgac agcgatgaca cgaccaccat tttctttgac agagcgaagg
     9181 gtggcagcag cttcctcaga aagttgatag aactctgagt gcatttcgtg ttcgtccaga
     9241 ttatccacag aaacaggtct aaaggttccg agtccgacat ggagagtcag atagactaga
     9301 tgaacaccct tagcttggat ttctgccagc agttctttgg tgaagtgaag accagcagtc
     9361 ggtgctgcag cagagccgct ttccttggcg tagacggttt gataacgttc acggtcatct
     9421 aatttttcgt ggatataagg tggcagaggc atttctccca gactttccaa gacttctagg
     9481 aaaattcctt ggtattcaaa gcggacaatg cgtcccccgt gggtcaattc ttctgtaacg
     9541 acagcgctga ggcggccatc accaaagctg atacgagtac cgaccttgag gcgtttggca
     9601 ggtttagcca gaacttccca ctcgtctcca ctagtgttct taaggaggag aagttccaca
     9661 tgacctcctg tctccacttt ttgaccatag aggcgggcag ggagaactcg ggtgtcgttc
     9721 atgacaaggg catcaccagg ttccagcata tcaataatag agtggaagtg tttatcttgc
     9781 atttctcctg tctcacggtt gacgatgagg agtttggagg catcacgttt ttcaaggggc
     9841 gtttgggcaa tcaattcctc tggcaagtgg aaatcaaaat cagctgtatt catatatttg
     9901 ttcattcttt ctaagttcta atcctatcca ttataacacg tttcaagttt ggacgctctt
     9961 tttttagaaa ttaaatcgtt ttcacttgac aaaaattggt ctataccata taataaatat
    10021 agacagaaat ggaggatgaa aagatgaaag ttattaaagt tgaaaaccaa gttcaaggtg
    10081 gaaaagttgc ttttgagatt ttgaaggaaa aattggctaa tggagctcaa actctaggac
    10141 ttgcgacagg aagtagccca cttgaatttt acaaggaaat tgttgagagt gaccttgatt
    10201 tttcaaatct aaccagtgtc aaccttgatg agtatgtggg ccttgatggg gacaatccac
    10261 agtcttatcg ttacttcatg caagaaaact tgttcaacca aaaaccattt aaagaaagtt
    10321 tcttgcctcg tggtgttaag gacaatgctg aagctgaagt tgaacgctac aaccaaattt
    10381 tggctgacca tccagttgac ctccaaatct tgggaatcgg tcgcaatggg catatcggct
    10441 ttaatgagcc tggtactcca tttgacagtc aaacgcatct agtagaactt gaccagtcta
    10501 ctatcgaagc caatgcacgc ttctttgcca agattgaaga cgtcccaacc caagctattt
    10561 caatggggat taaaaacatt ttggatgcca agtctattat tctttttgct tacggtgagt
    10621 cgaaagcaga agccattgcc ggaacagtat ctggcccagt gactgagaac ctacctgcaa
    10681 gtagcctcca aaatcaccct gatgtaacca tcatcgcaga tgctgaagcg cttagcttac
    10741 tcgaaaaata aaaagtataa gaaccgcttg ctctttggag tgagtggttt tagacatata
    10801 aaacttcaac ttaactttag gaggacacat gaataaagaa gaatttttaa aaataaaaga
    10861 agcatataag agtgctagaa cggaagaaag aaaaagtata ataggcttca ttacaaaaaa
    10921 gaaagataag gaggggaatt ttctttttac taagtcaaaa gataaaccat ataccacaag
    10981 aaatcaatat tcaggaggcg gaggaaataa aaagtacacc tcgggtagta gattatctag
    11041 gccatatgat ttatcaaatc acatgtggat tgatttgtca tataaaggaa atgacatctt
    11101 aatctcttta cagtcttttg atattgatcc aaatagtaaa gaacttcacg tcttatatga
    11161 tagaataggc atcttatttg aacaatctaa aaaaattcca atttttaaag attgctatac
    11221 aataactaaa gtcagtgatg cttttcttaa aatggaaaca acaaactggg aattaccttt
    11281 atctaaagca gatatggaag agatggtgaa ctatattatt aatcattatg aagaataaaa
    11341 aacttagttt cctcttgaca attattcctt ttacgtgtag aatgaaatag atattgaact
    11401 tgaagggagt gaaaaaaatg tctaaaacag tagtacgtaa gaatgaatct cttgacgacg
    11461 cacttcgccg tttcaaacgt gcggttacta aagctggtac tcttcaagaa acacgcaaac
    11521 gtgaattcta tgaaaaacct tctgtaaaac gtaaacgtaa atcagaagta gctcgtaaac
    11581 gtaaaaaatt ctaattgaaa tgaaaggcta gagaaatcta gtcctttttc ttttaaataa
    11641 atactccaaa gcctgcaaaa atctgaaact tcctcctaca atttgatata atagagagaa
    11701 gaactcattt gaaggaggaa atgatgtcgg ttttagtaaa agaagtgatt gaaaagctta
    11761 gactagacat tgtctatggt gaaccagaat tgcttgaaaa ggaaatcaat atagcggata
    11821 ttacgcgacc tggtcttgaa atgacaggct attttgacta ctatacacca gagcggattc
    11881 aacttttggg gatgaaggag tggtcttatc tgatcagcat gccttccaac agccgttatg
    11941 aagttttgaa aaaaatgttt ctacctgaga caccagcagt cattgttgcc cgtggtttgg
    12001 tggttccaga ggagatgtta aaggctgcta gagaatgtaa gattgctatt ttaaccagcc
    12061 gtgcagctac cagtcgttta tctggagagt tatctagcta tctggattct cgtttggcag
    12121 aacgtaccag tgtgcacggt gtcttgatgg atatttatgg gatgggcgtc ttgattcagg
    12181 gagatagtgg aattggtaag agtgagacag gtcttgagct tgtcaaacgt ggtcaccgtt
    12241 tggtagccga tgaccgtgtc gatatctttg ccaaggatga gattactctc tggggtgaac
    12301 cagctgaaat tttgaaacac ttgattgaaa ttcgtggggt tggtattatc gatgttatga
    12361 gtctctacgg tgcgagtgct gtcaaggatt cttcacaggt tcagcttgct gtctatttgg
    12421 aaaattacga tacgcataag acctttgatc gtcttggaaa caatgcagag gaacttgaag
    12481 tttctggcgt agccattcct cgtattcgta ttccagttaa aacaggtcgt aatatctctg
    12541 ttgtgattga ggcagctgcc atgaattatc gtgccaagga aatgggcttt gatgcgaccc
    12601 gtttgttcga cgaacgactg acaagtctca tcgctcgaaa tgaggtgcaa aatgcttgat
    12661 ccaattgcta ttcaactagg acccctagcc attcgttggt atgccttatg tattgtgaca
    12721 ggcttgattc ttgcggttta tttgaccatg aaagaagcac ctagaaagaa gatcatacca
    12781 gacgatattt tagattttat cttagtagcc tttcccttgg ctattttagg agctcgtctc
    12841 tactatgtta ttttccgatt tgattactat agtcagaatt taggagagat ttttgccatt
    12901 tggaatggtg gtttggccat ttacggtggt ttgataactg gggctcttgt gctctatatc
    12961 tttgctgacc gtaaactcat caatacttgg gattttctag atattgcggc gcctagcgtt
    13021 atgattgctc aaagtttggg gcgttggggt aatttcttta accaagaagc ttatggtgca
    13081 acagtggata atctggatta tctacctggc tttatccgtg accagatgta tattgagggg
    13141 agctaccgtc aaccgacttt cctttatgag tctctatgga atctgcttgg ctttgccttg
    13201 attctgattt ttagacggaa atggaagagt ctcagacgag gtcatatcac ggccttttac
    13261 ttgatttggt atggtttcgg tcgtatggtc atcgaaggta tgcgaacaga tagtctcatg
    13321 ttcttcggac ttcgagtgtc ccaatggctg tcagttgtcc ttatcggtct cggtataatg
    13381 atcgttattt atcaaaatcg aaagaaggcc ccttactata ttacagagga ggaaaactaa
    13441 atgttagaag ttgcatatat tcttgttgcc ttagctttga ttgtcttttt ggtctatctg
    13501 atcattactg tacaaaagct tggtcgtgtc atcgatgaaa cagaaaagac gattaaaacc
    13561 ttgacttcag atgtggatgt gaccttgcat cacaccaatg agttgttggc taaggtcaat
    13621 gtcttggcag atgatatcaa tgtcaaggtg gctacgattg atccactctt cagtgctgtt
    13681 gcagatttat ctctatctgt ttcagacctc aatgaccatg cgcgtgtctt gagcaagaaa
    13741 gcttcatcag ctggttcaaa aacactcaag actggtgcaa gtctgtcagc tcttcgtctt
    13801 gcaagtaaat ttttcaaaaa ataaaaaagg agaatcctta tgggtaaatt atcctcaatc
    13861 cttttaggaa cggtttcagg tgcagctctt gccttgtttt taacaagtga taagggcaaa
    13921 caagtttgca gtcaggctca agattttcta gatgatttga gagaagatcc ggagtatgcc
    13981 aaggagcaag tctgtgaaaa actgacagaa gttaaggagc aggctacaga ttttgttctg
    14041 aaaacaaaag aacaggttga gtcaggtgaa atcactgtgg acagtatact tgctcaagct
    14101 aaatcctatg cttttcaagc gacagaagca tcaaaaaatc aattaaataa tctcaaggaa
    14161 caatggcaag aaaaagccga agctcttgat gactcagaag agattgtgat tcatataaca
    14221 gaagaataaa ccatcaccat ctccggacgg actatgtatc tggggatggt gatttttatc
    14281 tggaatctag tctttgtggt ataataatta ctatgcagaa aaaaccaacg tcagcctatg
    14341 tgcacatccc attttgtacc cagatttgtt attattgtga tttttcaaag gtcttcatca
    14401 aaaatcagcc agtcgacagc tatttagagc atctgctgga agagtttcgt tcttatgata
    14461 ttgaaaagtt gtcaaccctt tatatcggtg gtggaacacc gacagccctg tcggctccgc
    14521 aactggaggt gttactgaat ggcttgacta aaaacttgga tttgtctgtc ttggaagagt
    14581 tgaccattga agccaatcca ggcgatttgg atgcggataa gatagctgtt ttgaaaaatt
    14641 cggctgtcaa tcgtgtttcg ctaggtgtcc agacctttga tgataagatg ttgaaaaaga
    14701 ttgggcgcag tcatttggag aaggatattt atgaaaatat cgatcgcctg aaactggctg
    14761 gttttgacaa catctccatt gatttgattt atgctctgcc tggtcagacc atggagcaag
    14821 taaaggaaaa tgtggctaaa gccattggat tggatattcc ccacatgagt ttgtatagtt
    14881 tgattttaga aaaccatacg gtctttatga accggatgcg acgtgggaaa ttgcctctgc
    14941 ctaaggagga actagaagcg gagatgtttg agtacatcat tgcagagctg gagcgagcgg
    15001 gttttgagca ttatgagatt tctaatttct ccaaacccgg ttttgaaagt cgtcataatc
    15061 tcatgtactg ggacaatgct gaatactatg gtattggtgc aggggcatct ggttatgtca
    15121 atggagtacg ctataaaaat catggtccca ttcgtcatta tctcagtgcg gttgaggaag
    15181 gcaatgcttg tattacagaa gatcacctga gtcaaaagga gcaaatggaa gaagaaatgt
    15241 tcttgggact ccgcaagaaa tccggggttt ccatggcgcg atttgaggaa aaatttggac
    15301 agtcttttgc tggactttat ggagaaattg tcagagattt ggttcaacaa ggcctcatgc
    15361 agattgaggg tgaccacgtt cgcatgacaa agagaggtct ctttttggga gatactgtag
    15421 cagaacgatt tattttggag taggatcatg ggcttaactt atcaaatgaa aatgaaaatt
    15481 ccttttgata tggctgatat gaacggtcat atcaaacttc cagatgtgat tttgctgtca
    15541 ctgcaagttt cagggatgca atcgattgaa ctgggagtta gtgataaggc cattttggaa
    15601 gactataatc tggtctggat tatcgcagaa tatgatattg aggtggttcg tttgcctcgt
    15661 tttgcggaag aaattaccat cgaaacggaa gccttgagct acaatcgact tttttgctac
    15721 cgtcgcttta ctatttataa tgaagcgggg caggagctca tccatatgat ggcgaccttt
    15781 gttctcatgg accgcgacag tcgaaaagtc catgctgttg aacctgagat tgtggctcct
    15841 taccagtctg attttgataa aaaacttatc cgtggaccga agtatgaatc cttggaagag
    15901 ccgatcagca aggattacca tgttcgtttt tacgacttgg atatgaatgg tcatgtcaat
    15961 aacagtaaat acttggactg gatttttgag gtcatgggag cggatttttt gacccactat
    16021 attcccaaga aaatcaacct caagtatgtc aaggaagttc gaccaggtgg ggtgattaca
    16081 tcggctgttg aacggactgg actggaaagc aagcatgaaa ttacaagtga tggggttatc
    16141 aatgcccaag caatcattac ttggcaagaa ataaaaaagg tttagggaga aatagatgaa
    16201 atataaaggc tatttaatcg atttagacgg aaccatttat aaggggaaag accgaatccc
    16261 tgctggagag acttttgttc atgaattgca aaagcgggac attccctatc tctttgtaac
    16321 caacaataca acccgcactc cagagagtgt taaggagatg ttggctcaga attttaatat
    16381 cgatacgcct ctatcgactg tctacacagc gactttggca accatcgact atatgaatga
    16441 tttggggctt gaaaagaccg tctatgtcgt cggagaagca ggactcaagg aagccatcaa
    16501 ggcggctggt tatgtggaag acaaggaaaa ccctgcctac gtggtagttg gtctggattg
    16561 gcaagtcgac tatgaaaaat ttgccacagc aactcttgct attcaaaagg gtgcccattt
    16621 tatcggaacc aatcctgacc tcaacatccc gacggaacgt ggtcttttgc caggtgctgg
    16681 ctcactgatt acgctgcttg aagtagcgac acgagtgaag ccggtttata tcggaaaacc
    16741 aaatgccatc attatggaca aggcggttga gcacttaggt ttggaacgtg aagagttaat
    16801 catggttggg gacaattatt tgactgatat ccgggctggg attgacaatg gcattccaac
    16861 actcttggtg acgacaggtt ttaccaaggc agaagaagta gctggcctgc caatcgcacc
    16921 gacacatgtg gtttctagcc ttgcggagtg ggattttgat gaaaactaaa ttgacctttt
    16981 ggggctctat gctctttctc ctctccctct caatccttct gaccatttat ctggcttgga
    17041 ttttctatcc tatggagatt cagtggctaa acttaacgaa tcgagtctat ctaaaaccag
    17101 aaaccattca atacaatttt catatcttga tgaattatct gaccaatcct tttagtcagg
    17161 tcttacagat gcctgatttt cgttcgtcag cagctggtct gcaccatttc gcagtggtca
    17221 agaatctctt tcatttggtt cagctagtag ctctagtgac actgccaagt ttctatgtct
    17281 ttgtcaatag gattgtgaaa aaggactttt tgtctcttta tcgaaaaagt ctcctgactc
    17341 tagtagtctt acctgtgatg attggacttg ggggagtttt gattggtttt gaccaattct
    17401 ttactctttt ccatcaaatt ctctttgtgg gagatgatac ctggcttttt gatccagcca
    17461 aggatcctgt tattatgatt ttgccagaga ccttctttct tcatgccttc ctcctctttt
    17521 ttgccctcta tgaaagcttc tttgggtatc tgtgtctgaa aagtcgtagg aagtgaaatg
    17581 aaagatgttt ttaatttgca tatataaaaa tatatatcgt ttaaaaccat cgttaagagt
    17641 gaattaacca aatccaattg tgtcaatcgt tcgcaaacag cctatttttc ttgaaaaaat
    17701 aggctttttt tctaaaaatc cctagtcaag cgccttattt ttttgtataa tagaagtagc
    17761 aaagtataga taagaagaga aaagcatgat tacactattt ctatcaccga gctgtacatc
    17821 atgtcgtaag gctaaggcct ggttagaaaa acataaggtt ccctttgtgg aacacaatat
    17881 tatgaccagt cctttaacaa gaaaagaatt gcaacacatc ctttccttga ccgaaaatgg
    17941 tactgatgac atcatttcaa ctcgttcaaa aatttttcaa aaattgaata ttgatgtaga
    18001 gagtatttcg gtatcggaat tgcttcattt gattgagcag tatcctagtc ttttgcgtcg
    18061 tccaattatt attgatgcca agcgtatgca aatcggtttt aatgaagatg agattcgtgc
    18121 ttttctccct cgtagttatc gtaagcaaga actaaaagaa gcaagaatga gagctggtat
    18181 tagttaatga acaaacagta tagttaccca ctagatttgt cgtggagcac tgaagaactt
    18241 gcttcagtgc tttctttttt taatgatgtt gaagctgcct atgaaggcaa agtagaggct
    18301 aaaaagttac tggactccta taagggattc aaagcggtcg tgccaagcaa gagcgaagag
    18361 aaacgtttgg gacgagaatt tgaaacggtt agtggctatt cactttaccg agcagttcag
    18421 gctgccaaag aaaaagggga aggaaagatt tctcttggaa agtaaatttg aatttgctaa
    18481 agagcttgtt aagaaagcag gccagtacat tcttgaccat atgcaggaag acttgcgtgt
    18541 tgaaaccaag tcctcttcaa cagatttggt gaccagactg gacaaagaag ttcaggaact
    18601 cttggttggt gagattttgt cccgttatcc tgaggataag atttgtgctg aagaaggttg
    18661 tctgcgagcc tcggttcaag agggcaaggt ttgggtcatt gatcccattg atggtaccaa
    18721 taattttgta gcccagcagg aagattttgc tgttatgatg gcttattttg aaaatggtca
    18781 gggacagttt ggtctgattt atgatgtggt caaaggggat tgttaccacg gtggtgggga
    18841 atttccagtt tgtctaaatg ataggcccct agctcctttt aaaactaaac cacttggaga
    18901 ttttctcatt gcagggaata gtggtatgct ggaaaccaat gaatgggggc tggctgattt
    18961 gagccgatcg gttcttggtg ttcgtgtcta tggaagtgcg gccattagtt ttgccaagat
    19021 tttgtcaggg cgtttgttga cctatctcac ttatctgcaa ccatgggatt atgccgcagc
    19081 tagtatttta ggggaaagtc tgggctatcg ggttgtgacc ctttttggtg aagctcctga
    19141 ttttcaaacc agacagccgg tcatgatggt gcctcttgag atgcaggagg aaattcagtc
    19201 ctatatttac gaaaggaaaa gaacttaaat gcaatttcca gaaggatttg ttgaaaaata
    19261 taaagagata ctaggagatg aggcaagaga ttttcttgcc tcttttgagg aggaagcggt
    19321 ttcggccttt cgggtcaatc ccttaaaaga agagcaactt tccttttctg atgccattac
    19381 tcaaacccct tggggccact atgggaaggt ttcagggaaa tcgcctgagc atgctacagg
    19441 tttagtttat tcgcaagaac ctgctgctca aatggtggct caagtagccc aacccagtcc
    19501 tggtatgaag gtcttggact tggctgctgc accggggggc aaatcaactc aactggcagc
    19561 ctatctagca ggtgaggggc tacttgtttc caatgaaatt tcaagcaaac gggctaagat
    19621 tttggttgaa aacatggagc gttttggagc gacaaatgtc gtggtgacca atgaatctgc
    19681 cgaccgcttg gtcaaggtct ttaaaggcta ttttgactta atcgttcttg atgccccttg
    19741 ctctggtgaa ggaatgtttc gtaagcaacc tgatgctatg gactattgga gcttagatta
    19801 tccgagtcaa tgtgctagct tgcaaagaga aattctggag gatgcagtga ccatgttagc
    19861 tgaaggtggt cgtctggttt attcgacctg tacctgggca cccgaggaaa acgaagagat
    19921 tgtcaattgg ttgctggaag agtatgattt tgacttgttg ccagtagagc atatcaatgg
    19981 aatggtagct ggtattgacc tgccagaaac ggctcggatg taccctcatc agtttaaggg
    20041 agagggtcag tttgttgccc atctacagtt taagggtaac aatccagctc ctaaatttaa
    20101 ggcaagtaag agtaacctca gccgtgaaca agttgccttg tggcaggaat ttgcccaaaa
    20161 ccatttgaag gtcaatctac cgggtatctt gcagactttt ggagaccagc tttatctctt
    20221 gccagaactt ttgccagatt tagggaagct caagattgct cgcaatggac tgcatctggg
    20281 cacttttaag aagaaacgct ttgagcccag tttcgctctt ggtttagcct tgaaaccgag
    20341 tcaggtcgaa cagtcggttg aaattggcca agaagcgttt gtcaagtatg cggctggaga
    20401 aaccgttcag ctggcagaaa gtctgccaaa tggttggtac caagttttgg ttaaaggcaa
    20461 tggcttgggc tttgcaaagg ttactggaaa tgttttgaaa aattattttc caaaaggcct
    20521 cagattcaaa tgaaaatgct agtcaaatat cttattctat gttatagtga aagtatggat
    20581 ttttttagta ggatgattct tgatatcttg attgccatca catgtagttt tactactcga
    20641 tgaaaatcaa agagcaaact aggaagctag ccatagatag ctcaaaacac tggtttgaag
    20701 agattttcaa agagtacaag aagtttagtt attagcgttc ttaccgcttg taaactagat
    20761 ttctcataaa atagaatctt ttccttttag ttgtaaacta gtctgggaga gtagagaggt
    20821 ttgagatacc tttctagctt ttggattatc atctgaggag agtaatttcc cttgcattaa
    20881 aaaggggaaa aagagacacg aaatgattat aatgggtgac aatgggggaa gggatagaca
    20941 agagatttta tccacatatg aaaaaaggag gttaggaaag agtaatatag cctatattat
    21001 ataaataatc aattgcgcag aaatttggta agaattcatg cgtcaactca taaagaacta
    21061 cttaaaaaat tcacagtatt cataattatt ttcgaggaga aaaacagtga aaaaaagaaa
    21121 aaagcttgct ctgtctctta tcgctttttg gctgacggct tgtttagtag gctgtgctag
    21181 ctggattgat cgtggagaat ccataacggc tgttggctca actgccttgc aacccttggt
    21241 tgaagtagcg gcagatgaat ttggcacgat ccatgttgga aaaacggtca atgtccaagg
    21301 gggaggttct ggtacaggct tgtcccaggt tcagtctggg gcagttgata taggaaactc
    21361 agatgtattt gctgaggaaa aagacggaat tgatgcttct gctcttgttg accacaaggt
    21421 cgcggtagct ggcttggctc tgattgtcaa taaggaggtt gatgttgata acctaacgac
    21481 agagcaactt cgtcaaatct tcataggtga ggtaaccaat tggaaagagg ttggtggtaa
    21541 ggacttaccc atctctgtta tcaatcgggc agccggctct ggttctcgtg ctacctttga
    21601 tactgtcatt atggaaggtc agtctgccat gcaaagtcag gagcaggatt caaatggagc
    21661 ggtaaaatca atcgtatcaa aaagtccagg agctatctct tatttatctc ttacctatat
    21721 agatgattcg gtcaaaagca tgaagttgaa tggctatgac ttaagtccag aaaatataag
    21781 tagcaataat tggcccttgt ggtcttatga gcatatgtat acattggggc agcccaatga
    21841 gttggctgca gaatttctca attttgttct ctcggatgag acccaagaag ggattgtcaa
    21901 aggattgaag tatattccga ttaaggaaat gaaggttgaa aaagatgctg ccggaactgt
    21961 gacagtgttg gaagggagac aataatgaat caagaagaat tagctaagaa aatgttgctt
    22021 ccatcaaaga attctcgtct ggagaaatta ggaaaaggtt tgacctttgc ctgtctttct
    22081 ttgatagtca tccttgtggc catgattttg gttttcgtag cgcaaaaagg cttgtcgacc
    22141 ttctttgtca atggtgtgaa tatctttgac tttcttttgg gaggaacttg gaatccttct
    22201 agtaaagaat ttggtgccct tcctatgatt ttgggttcct ttatcgttac cattctctca
    22261 gcccttatcg caacaccctt tgctattggt gcagcagttt ttatgaccga agtatcacca
    22321 aaaggggcga agattttgca accagctatt gaactcctgg ttgggattcc ttcagtagtg
    22381 tatggattta ttggcttgca agtcgtcgtt ccctttgttc gcagtgtctt tggtgggact
    22441 ggttttggga ttttgtcagg gatttccgtc ctctttgtca tgattttgcc gaccgtaacc
    22501 tttatgacaa cggatagctt gcgtgcggtt cctcgttatt atcgtgaagc cagtttcgct
    22561 atgggagcca ctcgctggca gactatctgg cgtgtgatct tgaaggcggc ccgttctggt
    22621 attttcactg cagtggtctt tgggatggcg cgtgcctttg gtgaggcttt agctatccag
    22681 atggttgtcg gaaactcagc tgttatccca acttccttga ccacaccagc tgcaacttta
    22741 acttctatat taactatggg aattgggaac actgtcatgg gaactgtaaa taataatgtt
    22801 ctctggtcac tggccttggt actgctcttg atgagtttag tttttaacag tgtgattaaa
    22861 ttgattacga aagaaagagg aaagaaaaat tatgcgcgct aagaaattag ataaacttgc
    22921 aacagctgtc ctctatacga ttgctagcat cattgtgaca atcttggctt ccttgattct
    22981 ctatatcttg gttcggggct tgccccatat ctcttggtct ttcttgactg gaaggtcttc
    23041 tgcttttcaa gcaggtggtg ggattggcat tcagctttac aattcctttt tcctattggt
    23101 cattaccttg attatttctg tacctctttc tatgggagct gggatttact tggctgaata
    23161 tgctaaaaaa ggtcctgtta ccaactttgt gcggacttgt attgaaatct tgtcctcttt
    23221 accatcagtg gtggtgggtc tctttggtta cttgatcttt gtagtccagt ttgagtatgg
    23281 attttcaatc atttcaggtg ccttggcctt gacagtcttt aacttgcctc agatgacgcg
    23341 taatgtagag gatagtttga aacacgttca ccatacccaa cgtgaggctg gtctggctct
    23401 tgggatttct cgctgggaga cagtggttca tgttgttatt ccagaagcgc ttccaggtat
    23461 tgtaacgggt gtcgtcttgg catctggtcg tatctttggc gaagctgcag ctctgatcta
    23521 tacagcaggg caatcggcgc cagctcttga ctggtctaac tggaatatcc tcagtgtgac
    23581 tagccccatc tctatcttcc gtcaagcaga aaccttggct gtccatatct ggaaagtcaa
    23641 tagtgaaggc actattccag atggaaccat tgtatcagca ggttctgccg ctgtgctcct
    23701 gatctttatc ctgattttta actttggagc tcgtaagttc ggaagctatc tacacaagaa
    23761 attaaccgct gcctaaagga gaagccatgt caacatataa ctgggatgag aagcatatcc
    23821 ttacctttcc tgaagaaaaa gtagcccttt ctactaagga tgtccatgtt tactatggta
    23881 aaaatgaatc cattaagggg attgatatgc aatttgaaag aaataaaatt acagctttga
    23941 ttggtccgtc gggatcgggg aaatctacct acttacgcag tctcaatcgc atgaatgata
    24001 ccattgatat tgctaaagta actgggcaga ttctctatcg tggaattgat gtcaaccgtc
    24061 cagaaatcaa cgtttatgaa atgcgtaaac acattggaat ggtttttcaa cgccccaatc
    24121 catttgctaa gtcaatttac cgtaatatta cctttgcgca tgaacgtgct ggagttaagg
    24181 ataagcaagt cctagatgaa atcgtagaaa cctcccttcg tcaggctgcc ctctgggatc
    24241 aggttaaaga cgatctccac aagtcagcct tgaccttatc aggtggtcag caacaacgtc
    24301 tctgtatcgc tcgtgccatc tctgttaagc cagatatcct cttaatggat gagccagctt
    24361 cagccttgga tccgattgcg accatgcaac tagaagagac catgtttgag ctcaagaaag
    24421 actttaccat catcattgta acgcataata tgcagcaggc tgctcgtgca agtgactata
    24481 caggcttctt ttacttgggt gatttgattg agtatgacaa gactgcaact attttccaaa
    24541 atgccaagct acagtccacc aatgactatg tatctggtca ctttggttag aaaggaaacc
    24601 gtatgacaga tgcgatttta caggtatcag acctgtccgt ttattataat aaaaagaagg
    24661 ctttgaatag tgtttcccta tctttccaac ctaaggaaat tacagccttg attggtccat
    24721 ctggatcagg gaagtcaacc ctcctcaagt ctctcaaccg catgggagat ctcaatccag
    24781 aggtgaccac aactggatcc gtggtgtaca atggtcacaa catctacagt ccgcgtacag
    24841 atacggttga attacgtaag gaaatcggaa tggttttcca acaacctaat cctttcccta
    24901 tgactatcta tgagaatgtt gtctacgggc ttcgtatcaa tggaattaag gataagcagg
    24961 ttctggatga agccgtagaa aaagccttgc aaggtgcctc tatctgggat gaggtcaagg
    25021 atcgtctata tgattcagct attggattgt caggtggtca acagcagcgt gtctgcgtgg
    25081 cccgtgtctt ggcaactagt cctaaaatca tcctcttgga tgagccaact tcggctttgg
    25141 atccgatttc agctggtaaa attgaggaaa ccttgtatgg tctaaaagac aagtacacca
    25201 tgcttctggt aacccgttcc atgcagcaag cttcacgtat ctctgataag acaggatttt
    25261 tcctagatgg agatttgatt gaatttaatg ataccaagca gatgttcctt gatccccaac
    25321 acaaggaaac ggaagactat attacaggaa aatttggata aggagatgaa agatgttacg
    25381 atctcaattt gaagaagatt tagagaaatt acataaccag ttctacgcta tgggacaaga
    25441 agtgctctca caaatcaatc gtacggtacg tgcttttgtc acgcatgacc gtgacctggc
    25501 aaaagaggtc atcgaagatg atgcagaagt aaatgaatac gaagtgaaac tggaaaagaa
    25561 atcatttgaa atgatcgcac tccaacaacc agtctctcaa gatttgcgta cagtcttgac
    25621 tgtccttaag gctgtatcag atgtggagcg tatgggggat cacgctgtag ccattgccca
    25681 ggcaaccatc cgtatgaagg gggaagaacg catcccagct gtagaggaag aaattaaaaa
    25741 aatgggacgt gaagttaaaa gcgttgttga agcagcactt gatctttatc ttaatggttc
    25801 tgttgacgac gcataccggg tggcctccat ggatgagcaa attaaccact attttgaaac
    25861 tatccgtgac cttgcgactg aagagattaa gaaaaatcca gaagccattg ttacgggtcg
    25921 tgattatttc caagttattt cctacttgga gcgtatcggt gactatgcta aaaatatctg
    25981 tgaatgggtt gtctactttg aaacaggtaa gattgtcgaa ctataaaata gtttaattct
    26041 gtataaaaag gagcttgaaa tcaactgatg gctccttttt ttgaacgaaa acatattttt
    26101 gagataaaaa tttaaaaaac acttgacaag taacttggat atcgttataa ttatacaaaa
    26161 ttaacagaga ggttgtttat ttatgaaatc aaaaaaatgg atatttgttt tatgtaattt
    26221 tcttgcaagt ttcttcttag tagcttgcca gtcaggttct aatggttctc agtcagctgt
    26281 tgaggccatt aagcaaaagg ggaaattagt tgtggcaacc agtcctgact atgcaccctt
    26341 tgaatttcaa tcattggttg atggaaagaa ccaggtagtc ggtgcagaca tcgacatggc
    26401 tcaggctatc gctgatgaac ttggggttaa gttggaaatc tcaagcatga gttttgacaa
    26461 tgttttgacc agtcttcaaa ctggtaaggc tgacctagca gttgcaggaa ttagtgctac
    26521 tgacgagaga aaagaagtct ttgatttttc aatcccatac tatgaaaaca agattagttt
    26581 cttggttcgt aaggctgatg tggaaaaata caaggattta actagcctag aaagtgctaa
    26641 tattgcagcc caaaaaggga ctgttccaga atcaatggtc aaggaacaat tgccaaaagc
    26701 tcaattaact tccctaacta atatgggtga agcagtcaat gaattgcagg ctggaaaagt
    26761 agatgctgtt catatggatg agcctgttgc acttagttat gctgctaaaa acgctggctt
    26821 agctgtcgca actgtcagct tgaagatgaa ggacggcgac gccaatgccg ttgctcttag
    26881 aaaaaatagt gatgatttga aagaagtggt agacaaggtc atccaaaaac ttaagaatga
    26941 aggaacttac caaagctatc ttgaaaaagc agcaagtcta actgaagttg aagaataaga
    27001 aaaagcagag ttggatgtca ttccaattct gcttttaaat agtttaaaac attttccaga
    27061 ttgtctaggg acaccttggc aaattgataa ggacaggtgc ttaaataggc ctcttcaaag
    27121 aagtccaagc ccagttgact gtgtttgaga ctggcgattt taggatactg tctcaggtct
    27181 agcaataaac catcgtgtag gggataatga ggaaggggac aaggtgtttt agttatcctt
    27241 tcctcgattt gtttttggta agattcatga ttggtcaagc gagccaaacg atttttttca
    27301 aacaattgac tgtcaatata gagtgacagg gccttttgca taatgaggtt gctgtcgtag
    27361 tctaggatat ttttgtaggc cacaaatgct tctttgatag catttggaag aatgagtgct
    27421 gtaatacgaa gggcaggaaa aaggctggtc gagaaggact tgatataaat gacatgctcc
    27481 tctgtatcaa gatagtggaa ggtttggccc ttcttggagt ccaaatcacc cagataatcg
    27541 tcctctacga tatagacatc atacttggca gctaagttaa gaatagatcg tttgtcttgc
    27601 tcagaatagg aatgtcccag aggatagtga aatctaggaa tggtgtagaa aaatttaatt
    27661 tttcctgttt tgaagtggcc ttccagctcc tccaagtcaa tcccatcaat gcctcgttca
    27721 atcgtttgat agtccagccc ctgtgcaatc aagaggcgat tcatccgatg gtaggttggc
    27781 tgttccacca agatttcctt ggcttgtcta ggaaaggata tttgagagag gataaacaag
    27841 gcttgttggg ttccagaagt cagtactagt tggttagcct tgcagtagag agcttgctca
    27901 aataggagtt tgtgaatgga ctgtcttagg tcttctaatc cttcttgatt gtcatagtag
    27961 ttgaagaggt agttttctcg tccaatcaag gtttcattga cacagagtcg gaaatcgtca
    28021 taggcactgg catgttcgtc ggtaacctcg atttctaggt cttgatgttg cccttgttct
    28081 aatacatagt agccactctg aggcttggca tagaggtatt gttcgtgccg taattccagc
    28141 agggctcgtt gaatggtgtc cttgctgcag tgaaagtcaa ggctcagttg acggatagaa
    28201 ggcaggcgac tacccgtcgg aaatcgttca gactcgatac catttttcag ataggaaacg
    28261 acctctttgt acttgctttg tttcttcatt ccagacctcc cttgattttg ttacattgta
    28321 cccttttttt tccttcttgg caatgtctag agcgtttctc tcgttcacat ctaggggcaa
    28381 atgtggtata cttaggagta agatttatag aataacagac aagaaagtga atggataaga
    28441 acgtgcagga accagtgaaa ttatttcaat acaatactct tggagccttg atggctggcc
    28501 tttatggtgg tactatgaca gtaggagaat tgctagaaca tggtgacctt ggtttgggaa
    28561 ccttggattc cattgatggg gaattgattg tcttggatgg caaggcttat caggccaaag
    28621 ggtcaggaga ccagccagaa attgtggaag tgtcaccaga tgcccttatt ccttacgctg
    28681 cagtggtacc gcatcaggca gaggtcattt tccgccagcg ctttgagatg acagacaagg
    28741 aattgaaaga acgaattgag tcttattatg atggggaaaa tcttttccgc tctatcaaga
    28801 ttcgggggga attttcacat atgcatgtgc gtatgattcc taagtcaaca cccgatacca
    28861 agtttgctga tgtcgcaacc catcaaccgg aatatagtcg tgacaatgtt gcggggacta
    28921 ttgttggttt ctggacgcct gagattttcc atggggtcag tgtggcaggc taccatctgc
    28981 acttcatatc agatgatttg accttcggtg gacatgtcat ggattttgtc atcaaggaag
    29041 gcattatcga ggtgggagca gttgaccagt tggaccaacg tttcccagtc caagaccgtc
    29101 aatacttgtt tgctaagttc aatgttgacg agatgaaaaa agatattgaa aaggcagaat
    29161 aggagaagaa aatgaccatt catatcatta ttaccatgtt gctgttgcta gcttttctga
    29221 taggaagcat ttggtttgcc aaaaagaaat accagattaa tctagctgtc ttgggcttgg
    29281 gtgcagtcgc tttctttgtc tcttcgcaga ttttggaaaa actggtgcat atcttgattt
    29341 tgcatcctca aaaagacggt agtattgccc tcttgcaaga tcatccgctt atctatatta
    29401 tctatggcct agccatggca gcattttttg aggaaacggc tcgtcttgtt ttcttcaaat
    29461 ggttggagaa aaagagaagt ttggaaaagg cagatgcctt ggcctatggc ctagggcatg
    29521 gtggcttgga gttgattttt ctaggcctta ttagtttact caatctttac atcgttcttt
    29581 cggcagttca aactcagaat ccacaggtta tgcaattact gtctgaaaat atgttaaaaa
    29641 ccattcagtc actttcggtc tggcagattt atttgcttgg ttttgagcga atcttggcgc
    29701 ttggtttcca attacttttg acagtttggg tttaccaagc tgttcgccag aagaaatgga
    29761 tttatctcct agcagcctat ggcttgcatg ccttctttga tctggcacca tctcttttcc
    29821 aagtaggctg gttgacaaat ccagtcttgg ttgaagtgat tctagcactg gagctcgttc
    29881 tggtcgccta tggaaccaag gaaatctttt gtaaaaaatc ataaaaaggg gggaacctct
    29941 ttttcttatg caaaatccaa acaaggtatt tttatggtcg tcaaatgtct ctaaaaatgg
    30001 tataatggaa tgaattttgt aaaaggaaga gtgacatgtc tgtaagagaa aaaatgcttg
    30061 aaatcttaga aggaattgat atccgtttta aggaaccctt gcatagctat agttatacaa
    30121 aagtaggtgg agaggctgat tatttggtct ttccacgaaa tcgttttgag ttggctcgcg
    30181 ttgtgaaatt tgccaaccaa gaaaatatcc cttggatggt tcttggcaat gcaagcaata
    30241 tcatcgttcg tgatggtggg attcgtggat ttgtcatctt gtgtgacaag ctcaataacg
    30301 tttctgttga tggctatacc attgaagcag aagctggggc taacttgatt gaaacaactc
    30361 gcattgccct ccgtcatagt ttaactggct ttgagtttgc ttgtggtatt ccaggaagcg
    30421 ttggcggtgc tgtctttatg aatgcgggtg cctatggtgg cgagattgct cacatcttgc
    30481 agtcttgtaa ggtcttgacc aaggatggag aaatcgaaac cctgtctgct aaagacttgg
    30541 cttttggtta ccgccattca gctattcagg agtctggtgc agttgtcttg tcagttaaat
    30601 ttgccctagc tccaggaacc catcaggtta tcaagcagga aatggaccgc ttgacgcacc
    30661 tacgtgaact caagcaacct ttggaatacc catcttgtgg ctcggtcttt aagcgtccag
    30721 tcgggcattt tgcaggtcag ttaatttcag aagctggctt gaaaggctat cgtatcggtg
    30781 gcgtagaagt gtcagaaaag catgcaggat ttatgatcaa tgtcgcagat ggaacggcca
    30841 aagactacga ggacttgatc caatcggtta tcgaaaaagt caaggaacac tcaggtatta
    30901 cgcttgaaag agaagtccgg atcttgggtg aaagcctatc ggtagcgaag atgtatgcag
    30961 gtggttttac tccctgcaag aggtagtggg gacctgacag agccccgatc ggttaatcta
    31021 tgaaaaagaa ggaatttatg ccaattgaaa aaaccaatta tcgaattcaa aaacgtctct
    31081 aaagtttttg aagacagcaa caccaaggtt ctcaaagaca tcaactttga gttggaagaa
    31141 gggaaattct acacccttct aggtgcatct ggttcgggga aatcaactat cctaaacatt
    31201 attgcaggtt tactggatgc gacgacagga gatatcatgc tagacggtgt tcgtatcaat
    31261 gatattccaa ccaacaagcg cgacgtacat accgtcttcc aatcctatgc cttgttccca
    31321 catatgaatg tgtttgaaaa tgttgccttt ccacttcgct tgcgtaaaat tgataagaaa
    31381 gaaattgagc agcgtgtagc ggaagttctc aagatggttc agttggaagg ttatgaaaaa
    31441 cgttccatcc gcaaactttc tggaggacaa cgtcagcgtg tggccatcgc ccgtgctatc
    31501 atcaaccaac cccgtgtggt cttgttggac gagcctttat cagcgctgga cttgaaattg
    31561 agaacagaca tgcagtacga attgcgtgaa ttacaacaac gattgggcat tacctttgtc
    31621 tttgtcactc acgatcagga agaagctctt gccatgagtg actggatttt cgttatgaat
    31681 gatggcgaga ttgtccagtc tggaacccct gtggacatct acgatgagcc aatcaaccac
    31741 tttgttgcca cctttatcgg ggagtcaaac atcttgccag gtaccatgat tgaggactac
    31801 ttggtcgaat ttaacggcaa acgctttgaa gcggttgatg gtgggatgaa gccaaatgaa
    31861 cctgttgagg tcgttattcg tccagaggac ttgcgcatta cccttcctga agaaggcaag
    31921 ctccaagtta aggtcgatac ccagctcttc cgtggggtgc attatgaaat tatcgcctat
    31981 gacgaacttg gaaatgaatg gatgatccac tcaacccgta aggccatcgt gggtgaggaa
    32041 atcggtctgg actttgaacc agaagacatc cacatcatgc gtctcaatga aaccgaagaa
    32101 gagttcgatg ctcgtatcga agaatacgtg gaaatcgaag agcaagaagc aggtctgatc
    32161 aatgcgatcg aggaggaaag agatgaagaa aacaagctct aaactctttg tagtgcccta
    32221 catgctttgg attgccctct ttgtattggc acccttggtc ttgattttcg gacaatcctt
    32281 tttcaacatt gaaggccagt ttagtttaga aaattataaa tcttactttg cgtcacaaaa
    32341 cttgacctac ctcaaaatga gtttcaactc agtgctttat gcagggattg tgacctttgt
    32401 aaccttgctt atcagctatc caacagccct ctttttgacc cgtctcaagc accgtcaact
    32461 ctggctcatg ctgattatcc ttcctacctg gatcaatttg ctccttaaag cctatgcttt
    32521 tatcgggatt tttggtcaaa atggctctat taaccaattc ttggaattta tcggaattgg
    32581 ttcacaacag ttgcttttta ccgatttttc ctttatcttt gtcgcaagct acatcgagct
    32641 cccctttatg attttgccga ttttcaatgt cttagacgat atggataata atctcatcaa
    32701 tgctagttac gaccttggtg caactaagtg ggagaccttc cgtcatgtca tcttccctct
    32761 atctatgaac ggtgtgcgaa gtggggttca gtcggtcttt atcccaagtt tgagtctctt
    32821 catgctgacc cgtttgattg gtgggaaccg cgttatcacc ttggggacgg ctattgagca
    32881 gaattttcta accaatgaca actatggtat gggttcaact atcggtgtga ttctcatcct
    32941 gaccatgttc atcaccatgt gggtgactaa ggaaaggaga gaacgatgaa aaaatttgcc
    33001 aacctttatc tgggactggt ctttctggtc ctctacctgc ctatctttta cttgattggc
    33061 tatgccttta atgctggtga tgatatgaat agctttacag gttttagctg gactcacttt
    33121 gaaaccatgt ttggagatgg gagactcatg ctgattttgg ctcagacatt tttcttggcc
    33181 ttcctatcag ccttgatagc gaccattatc gggacttttg gtgccattta catctaccag
    33241 tctcgtaaga aataccaaga agcctttcta tcactcaata atatcctcat ggttgcgcct
    33301 gacgttatga ttggtgctag cttcttgatt ctctttaccc aactcaagtt ttcacttggc
    33361 tttttgaccg ttctatctag tcatgtggcc ttctccattc ctatcgtggt cttgatggtc
    33421 ttgcctcgac tcaaggaaat gaatggcgac atgattcatg cggcctatga cttgggagct
    33481 agtcaatttc agatgtttaa ggaaatcatg cttccttacc tgactccgtc tatcattgct
    33541 ggttatttca tggccttcac ctattcgtta gatgactttg ccgtgacctt ctttgtaaca
    33601 ggaaatggct tttcaaccct atcagtcgag atttactctc gtgctcgcaa ggggatttcg
    33661 ctagaaatca atgccctttc tgctctagtc tttctcttta gtattatcct agttgtaggt
    33721 tattacttta tctctcgtga gaaggaggag caagcatgaa aaaaatctat tcatttttag
    33781 caggaattgc agcgattatc cttgtcttgt ggggaattgc gactcattta gatagtaaaa
    33841 tcaatagtcg agatagtcaa aaattggtta tctataactg gggagactat atcgatcctg
    33901 aactcttgac tcagtttaca gaagaaacag gaattcaagt tcagtacgag gcttttgact
    33961 ccaacgaagc catgtacact aagataaagc agggtggaac gacctacgat attgccattc
    34021 caagtgaata catgattaac aagatgaagg acgaagacct cttggttccg cttgattatt
    34081 caaaaattga aggaatcgaa aatatcggac cagagtttct caaccagtcc tttgacccag
    34141 gtaataaatt ctccatccct tacttctggg gaaccttagg aattgtctac aacgaaacca
    34201 tggtagatga agcgcctgag cattgggatg acctttggaa gctggagtat aagaattcta
    34261 tcatgctttt tgatggggcg cgtgaggtgc tgggactagg actcaattcc ctcggctaca
    34321 gcctcaactc caaggatccg cagcagttgg aagagacagt ggataagctc tacaaactga
    34381 ctccaaatat caaggctatc gttgcggacg agatgaaggg ctacatgatt cagaataatg
    34441 ttgcaatcgg cgtgaccttc tctggtgaag ccagccaaat gttagaaaaa aatgaaaatc
    34501 tacgttatgt ggtaccgaca gaggccagca atctttggtt tgacaatatg gtcattccca
    34561 aaacagttaa aaatcaagac tcagcctatg cctttatcaa ctttatgttg aaacctgaaa
    34621 atgctctcca aaatgcggag tatgtcggct attcaacacc aaacctacca gcgaaggaat
    34681 tgctcccaga ggaaacaaag gaagataagg ccttctatcc cgatgttgaa accatgaaac
    34741 acctagaagt ttatgagaaa tttgaccata aatggacagg gaaatatagc gacctcttcc
    34801 tacagtttaa aatgtatcgg aagtaggaga taaacgtaag aagacgaatc agtcaagctg
    34861 gttcgttttt aaggaataga agtcagtttt tagagcccta tctttttcta ttctagttgt
    34921 ttatttgttt atttgcttat ttgcttgcct agtagtatac taagcctata ctcttcaaac
    34981 cacgtcagcg ttgccttgcc gtactcaagt acagcttgaa gctagcttcc tagtttgctt
    35041 tttgattttt attgagtatt aaccttacag aaagcggcaa caaataatga aaatgtctac
    35101 ttttttcaaa aaaagtttct ggccaacctt tatgattgtt aaccaaactg ctatactatt
    35161 ccatttaaat gatggcttgg atcgacaata cctaacaact gagtccatat attgggtgat
    35221 aggcaccttt atatttggaa atattctagt agctgtgttt agtaatatga aaatttggga
    35281 taaaaagaaa aatggcagta agaaaaaata tatcctgaaa aagtaatcag agatgtaggg
    35341 aattggtcta attcaacgga gatcatttcc agttgacgca agcttaaaaa aacgttataa
    35401 taagaaagtt gagaattgat tttcacttgt cttagtccag agaaatggcg gtgctgcgag
    35461 ccatctaagc taggaagtca tgctactcaa tcatacaatt gcataagaac aagagaatga
    35521 caagttcatt gaatgaaggt ggtaccgcgg tttttcgccc ttcgtgatat gagcttgtct
    35581 tttgattttt ggaggtgttg atgaaaacat ttcttgtcaa acaaaagttt cgtcttggag
    35641 gcgaacgctt cgctatcaag gatgacaggg gagaaattgc ctatcaggtg gagggatcat
    35701 tttttaagat tcccaaaact tttaccatct atgatgcggc tggtgaacaa gtcagtcaga
    35761 tcagtaaaga aatcttgacc ttgcttcctc gttttgagat tcagcttcgg gatggctcga
    35821 gttttgtcat tcgtaagaag ttgaccttct ggcgagataa gtatgagttt gataatctag
    35881 gtcttcgtat cgagggcaat atctgggatt tgaatttcaa attgctggat gatcgcgatc
    35941 agttgattgc ggaaattaag aaggaactct tccatctgac ctctacctat accgtaacgg
    36001 ttcttgaaga cgcttatgca gacctagtca tttccctctg tgtcgcgatt gactatgtgg
    36061 aaatgctgga aagccaatca cattaaacaa gtgaataagg agacaatatg aaacaactat
    36121 ctagtgcaca agtacgccaa atgtggcttg atttctgggc gaccaaaggt cactcagtag
    36181 aaccatcagt aagtttggtt cctgtaaatg acccaactct tttgtggatc aactctgggg
    36241 tagcaaccct taagaaatac tttgacggga ccattatccc tgaaaatcca cgtattacca
    36301 atgcccaaaa ggctatccgt accaacgaca tcgaaaacgt agggaagact gcgcgtcacc
    36361 ataccatgtt tgaaatgctg gggaacttct ctatcgggga ttacttccgt gacgaagcta
    36421 tcacttgggc ttatgagctt ttgacaagcc ctgaatggtt tgatttccct gctgaaaaac
    36481 tttacatgac ctactatcca gacgataaag attcttacaa ccgctggatt gaagtgggag
    36541 tggatccaag tcacttgatt ccaattgagg acaacttctg ggaaatcggt gcgggacctt
    36601 ctggaccaga tacagaaatc ttctttgacc gtggggaagc ctttgaccca gaaaatatcg
    36661 gtcttcgcct gcttgcagaa gatattgaaa acgaccgtta tattgaaatc tggaacatcg
    36721 ttttgtcaca atttaacgca gaccctgctg ttcctcgtag cgaatacaag gaattgccac
    36781 ataagaacat tgatacgggc gctggtttgg agcgtttggt ggccgttatc caaggggcta
    36841 agaccaactt tgaaacggac ctcttcatgc cgattatccg tgaagtcgag aaattgtctg
    36901 gtaaggttta tgaccaagat ggcgacaaca tgagcttcaa ggttatcgca gaccacattc
    36961 gttctctttc atttgctatc ggtgatggtg cccttccagg aaatgaaggt cgtggttatg
    37021 ttcttcgtcg tcttctccgt cgtgcttcta tgcatggtca aaaattgggt atcaacgagc
    37081 ctttccttta caaattggtt ccaactgttg gaaaaatcat ggaaagctac tacccagaag
    37141 tgcttgagaa acgtgacttt attgagaaaa tcgttaagag cgaagaagaa tcatttgccc
    37201 gtacccttca ctcaggtcaa cactttgccc aaggcattgt ggcagacttg aaagaaaaag
    37261 gtcaatctgt cattgctggt caagatgtct ttaaactcta tgatacttat gggttcccag
    37321 ttgaattgac tgaagaaatc gctgaagaag ctggtatgac tgtagaccgt gaaggttttg
    37381 aagcagccat gaaagaacag caagaacgcg cgcgtgcgtc agctgtcaag ggtggctcaa
    37441 tgggtatgca aaatgaaact cttcaaaaca tcactgtaga aagtgtcttc aactacaata
    37501 ctagccaatt gtcttctaaa ttggtagcta tcgttgctga caatgcagaa gtaggagctg
    37561 tttcagaagg aactgcctct cttatctttg cggaaacgtc attttatgct gaaatgggtg
    37621 gacaggtagc tgactacgga caaatcttgg atgagtcagg taagattgtg gctactgtga
    37681 ccaatgttca gaaagcccca aatggtcaag cccttcatac agttgaagtc cttgcaccgc
    37741 ttgccttgaa ccaagaatat accttggcaa ttgatagcaa tcgccgtcac cgtgtcatga
    37801 aaaaccacac tgcgactcat ttgcttcacg ctgcccttca caatatcctt ggaaaccacg
    37861 caacacaggc aggatctctt aacgaagttg aattccttcg ctttgacttt acccacttcc
    37921 aagcagtaac tgctgaggaa cttcgtgcga ttgaacagca agttaacgag aaaatttggg
    37981 aagcacttga agtgaagaca gttgaaacgg atattgacac tgctaaagaa atgggagcta
    38041 tggccctctt tggtgagaaa tacggcaagg aagttcgtgt cgtgactatc ggtgactact
    38101 ctattgaact ttgtggtggt actcatgttg acaacacttc tgagattggt ctcttcaaaa
    38161 ttgtcaaaga agaaggaatc ggttcaggaa ctcgccgtat cttggcagtg actggtaagg
    38221 aagcctttga agcctatcgt gaacaagagg atgctcttaa agctatcgca gcaaccttga
    38281 aagcacctca agtcaaggaa gtacctcaca aggtagaagg acttcaagaa caacttcgtc
    38341 aacttcaaaa agaaaatgct gagttgaaag aaaaagccgc agctgcagcc gcaggcgata
    38401 tcttcaaaga tgttaaggaa gtcaacggtc atcgttacat tgctagtcaa gtgtctgtat
    38461 ccgatgccgg tgcccttcgt acttttgcag ataactggaa acaaaaagac tactctgatc
    38521 ttcttgtcct agttgccgct atcggtgaca aagtcaatgt ccttgtagca agcaagacaa
    38581 aagaccttca tgcaggaaac cttgtcaaag aattagcacc aatcatcgat ggacgtggtg
    38641 gtggtaaacc agacatggcc atggcaggag gaagcaacca agctaagatc caagaattgt
    38701 tggatgcagt agcaggtaaa ttgtaatcaa gtaaagatct atccatttgg gtaggtcttt
    38761 ttgtgaatac aaaaaagcca aatccgcttg gacctagctt ggttattatg agctattaga
    38821 tggtattgac tgcccagaca cttacggatc tagctgagac agggaattgt ccataacctt
    38881 cctcatcaat tgtaacttga ccttggtggt taccaagtaa atctacaaag gtttgattag
    38941 tccattcttg accgacaaac attgacttgc tgttttcttg gtcatttgag ataaggactg
    39001 cgattgggga ttgattttca gcacctgaac gtacccaacc gatacagtta gcatggtcaa
    39061 agtagtcatt ttgttctcca taggccaagt cttttcggat ggctaggagg cggtcaagga
    39121 tttctttgaa atcttcttga gcatactggc ctgaaatccc atagtagtct ccgtaaaaga
    39181 cacatggaag gccgtcttgg cgtaacaaaa tgagggcata ggctgctggc ttgaaccatt
    39241 cttcaacggt agactcaagg gcttgtcctc gttgggtatc gtggttgtcg acaaaagtca
    39301 cagccttgtc aggcttgagt tcaaccaggc tatctgtgaa aatgccacga aggtcatagt
    39361 ttgcgccagc ttgactggct tcaaagagat tctggtggag acgaacatcg acaaggtcaa
    39421 agtgttcttc cgttttttcg agatagtcca gattggcttc cttgtctggg ttccaaaatt
    39481 caccaaaaac atagaaatcg tcaccgtatt tttccttcat atcgcggatg aagttgcgca
    39541 taaagaaaga gtcaatatgc ttaacggcat ccaaacggaa accagctaca ccagtcgttt
    39601 ccatgaacca atcagcccag tcatagatgt tttggatgac ttcaggatgt ttaaagtcta
    39661 ggtcggcata catgaggtag tcgtagtttc cgttttcgtt atcgaccaat tccttgttag
    39721 cccagccctt gttgtcccct tggatcagat aaatcccaga tttactgcgt ttggcatcgt
    39781 agtctgtacc ggtgaagtgg taccaatgcc agtggaagcc attataggta tcttggcgac
    39841 catcgaaggt aaaactagtc cagccattga tggtgaaggg ttctccaagt tcaactgtac
    39901 ggtctacagg atcaacttcg ataacctgaa aggcttccct gttatcggca gcagccttgt
    39961 ggttgagaac tacatcggcc ataggttgaa ttccctgttc tttaagggct tgaatggctt
    40021 gaagatagtc ttctttgaaa ccatacttgg tgcggacagt ccctttttgg ttgaactctc
    40081 ctaagtcaaa taagtcatag accccatagc cgacatcttt ttcgttggtt gccttgaagg
    40141 ctggtggcat ccagacgtga ctgatcccca gatgagctag gtgtggagca ttttcagcca
    40201 gacgcgtcca gtgttgaccg tcgtggggca gataccattc aaagtattgc atgagtgttt
    40261 gattttgcat gatgtttcct cttacttgtc aatcttgttc tttattctat cataaagtat
    40321 ctctcggcgc aaacgtttgc gtaagataga aggaaactat tttaactact taaaataaag
    40381 tattgatttt tttgtatcaa agtgctagta tagcgatgta taatatagat aaagatagga
    40441 gttgtcccat gattgaattt caaaatgtta gtaagttgta tggtgataaa gaggccttga
    40501 gtaatctcaa tttgcagatt gaaaatggag agattatggg cttgattggt cataatgggg
    40561 ctggaaaatc gaccaccata aaatccctag tcagtatcat ttcacccagc agtggtcgta
    40621 ttttggtaga cggtcaggag ttatcggaaa atcgcttggc gatcaaacga aagattggct
    40681 acgtagcaga ctcgcctgac ttatttttac gcttaacggc caatgaattt tgggaattga
    40741 tcgcttcatc ctatgatctg actagctctg acttggagac tagtctagct aggctattga
    40801 acgtttttga ttttgctgaa aaccgctatc aggttattga aactctttct cacggaatgc
    40861 gtcagaaagt ctttgtcatt ggggcactct tgtctgctcc tgatatttgg gttttggacg
    40921 aacccttgac tggtttggat ccccaggccg cctttgattt gaagcaaatg atgaaggaac
    40981 atgcacaaaa aggcaagacg gtcttgtttt caactcatgt ccttgaggta gccgagcaag
    41041 tctgtgatcg gattgctatt ttgaaaaagg ggcatttgat ctattgtggt agtgtagaga
    41101 acttgaggaa agaccaccca gaccagtttt tggaaagtat ctaccttagt cttgctggta
    41161 gaaaagagga ggttgcggat gcgtctcaag gtcattaaaa aattagttga tatcaatatc
    41221 ctctattcat ctcaagaagc taatctggct aatctacgaa agaagcaggc taagaatcct
    41281 gggaaaaaag taaatgtttc tgctagagtc ctaagttctt acattttttc cagtctcttg
    41341 atgctcatct gttttagtaa tatagccatt cattttcctt ttgaggaaat gcctatttat
    41401 tttagctcga tggttgctat tttactggtg ctggcctttt caacttcttt cactgccttt
    41461 tacaatgtct tttatgagag taaggacctg gcctcctata ggccctatgc ctttaaagaa
    41521 tcagagatta taatggccaa aggtctgtct gtcctcttgc cagctctaac tggaattgta
    41581 ccaatcctag cttattttct agccctctat attagtctag ctccttctct ttggctgggt
    41641 ttgcctttga tgctactgtc cttgacctta ttatttgtct ctgttacttt agtgacggta
    41701 gtggcagtac atttcttggc tcagactagg gtcttcagaa agtatcagtc tattttttcg
    41761 aatgtgatga ttgggatagg agttctcata cctttaatat ttatcttctt tcttcagtcg
    41821 acttttggaa gtattgttga caaagttaga gacattccat ttctccttta tcctcttcat
    41881 atcttttaca aaatagcagt ggagcctttt tcgacagaag ccttagtggg tctgctcgct
    41941 tggataggac taactctctt cctgctttat ctgaccaaaa agaaggtcct tcctcgtttt
    42001 tatgacgtga tcctgcttaa cagtgaggag aaggtcaaaa aagaacgtcg cagcaaggag
    42061 aggatttcaa ctactaaaaa gggctttttc cgtatggttt tacgctacca cctcaccctc
    42121 ttgggacagg ggactggtgt gattacagtg ctttttacaa gtgctttcct tccttatctc
    42181 atgatgatca gtctgatttc caaaatccga gattctcaga tagttccaga cattcatcct
    42241 ccatactggt tacccttgtt ttttgtagga gtgtttatag cagttgtcaa taacaatatc
    42301 accagcctgc attcaattgc cttgtccttg gagagggaaa atgttgattt tctgaagagt
    42361 ttaccctttg actttgctcg ttatgtgaaa gtgaaatttt ggattatctt tgctgttcag
    42421 tcctttttac cagttctgac tttgctcggt ctttctctat atctaggctt gcccatcctt
    42481 tcgatgattt accttcttgt agtctggatc attgccagtg tcatcctttc ttgccaccat
    42541 tactttaagg acgttaaaaa tctgtcaacc aattggagta gcattacgga cctggtgaat
    42601 cgttcaaatg gcatagtcgc catagtttta ttgtttattt atagtgcaat cctgatggcc
    42661 cttgtaattg ggagcatatt cttggttcag tctctctccc ctatccttgc catcaacttg
    42721 ggagtaggag ctcttatcgt cttgcttgct cttgctattt ttggctatca ttattacctg
    42781 tcacgcatat tggcagaaat agaaaaaaga tgagatagtt ggttgcttgc ttgataaatt
    42841 caattcgaca aacgctttta tagtttgtta gaatgtagtt gtaaatgatt aagattggta
    42901 atcaaaaata tagggaggaa tgttttgaat aagaaatata atatagttct attattgttg
    42961 tttatagttt atttattggg atatttttca atttcaaaaa cgttaattcc tataatgtgt
    43021 gtgatccaag tatttttgat agaacatata tttagagttc gaaatagaat gatgcaaata
    43081 ggtgaaattt taattattgt tgcttctata atattattta ttgatagtat attgagtttg
    43141 taacaaaagg cttttctata aaatcaaatt ttccagatac ctattgaagc agatttattt
    43201 cttcatcttt cttctactac ctttgtcact aaatttgaca gacacatatt gctgattcaa
    43261 cctctctacc tataatctca cagttaacct gaggctagtt tcatagtttg ctatttgatt
    43321 ttcgttgata aaaagaaatg ctcctccaag atggaagagc attttttatt gtgattctta
    43381 cacatttact tcctagtttt gcaggaagtc tagtatacca ttttttaaaa gaagagtaaa
    43441 aaagcaaggg tagtttcttt tttgagaatt gtctaaaagt ttgatataat ggtagttatg
    43501 aatagaataa gagtcagcaa aagggttgaa aagaagcttg ctaaggggct agttttacta
    43561 gaagccagtg atcttgagaa tgtcaatctt aaggatcagg aagtagaggt gcagggtcag
    43621 gaaggaaact ttcttgggac tgcctacctt tctcagcaaa acaagggctt gggctggttt
    43681 gtcagcaaag acaaggtggc cttcaatcaa gctttctttg aaacgttgtt tagaaaagcc
    43741 aaagaaaaga gaaacgccta ctatcaagat gatttgacaa ctgcctttcg tctctttaat
    43801 caagagggag atggctttgg gggtctgaca gtggaccttt atggcgacta cgccgtcttt
    43861 tcttggtata actcttatgt ttatcagatt cgtcagacta tatcagaagc ctttagacag
    43921 gttttccctg aggttttagg agcttatgag aaaatccgct ttaagggttt ggactatgaa
    43981 tctgcccatg tttatggtca agaagcacct gactttttca ctgttttaga aaatggtgtc
    44041 ctgtatcaag tctttatgaa tgatggcttg atgacaggaa ttttcctaga ccagcatgag
    44101 gttcgcggta gtttagttga cggcttggct atgggtaaat ccttactcaa tatgttttcc
    44161 tacacagcgg ctttttcagt agctgcggcc atgggaggag ctagccagac aacttctgtt
    44221 gatctagcca aacgttcacg agaattgtct caagcgcatt ttcaggcaaa tgggctcagc
    44281 acagacgagc atcgttttat agtcatggat gtctttgagt atttcaaata tgccaaacgc
    44341 aaagacttga cctacgatgt gattgtccta gatccgccta gctttgctcg gaataaaaaa
    44401 caaactttct ctgtggccaa ggattatcac aagttgattt cccagagtct tgagatttta
    44461 aatccgggag ggattatcat tgccagtacc aatgctgcca atgtttcccg tcagaaattt
    44521 acagaacaaa ttgataaagg ttttgcagga agaagttacc agattttaaa caaatatggt
    44581 cttccagcag attttgccta taataaaaaa gatgaaagta gtaattacct caaggtgatt
    44641 agtatgaagg ttagtaaatg aaattaatcg tttcagtaat gccaagaagt ttagaggagg
    44701 ctcaggctct ggatgccacg aggtacttgg atgccgacat cattgaatgg cgtgccgact
    44761 atctgcctaa agaagcgatt ttgcaggtag ctccagccat ttttgaaaaa ttcgcaggcc
    44821 gtgagttggt tttcacgcta cgaactcgct ccgaaggtgg agaaatcgac ctttctccag
    44881 aagagtatat ccatctaatc aaggaagttg cgcaactcta tcaaccagac tatattgatt
    44941 ttgagtacta tagctacaag gatgtttttg aggaaatgct ggacttccca aatcttgttt
    45001 tgagttacca taatttccaa gaaacacctg agaacatgat ggaaatcttg tcagagttga
    45061 cgatcctaaa tccaaaactt gttaaggttg cggtgatggc tcacacggag caggatgtct
    45121 tagacttgat gaactataca cgaggcttta aaaccctcaa tcctgaacag gaatatgtga
    45181 ccatttctat gggtaaggtg ggcaaggtct ctcgtatcac tgcggatgtg actggttcga
    45241 gttggtcttt tgccagtctg gatgaggtta gtgcccctgg gcagatttct ctagctagca
    45301 tgaaaaaaat cagggagatt ttggatgaag cttgatggct atacacgttt agctgcagtt
    45361 gttgccaatc ctattaagca ttctatttct cccttcatcc acaatagagc ctttgaggcg
    45421 acagctacca acggtgctta tgtggcttgg gagattgaag cgagtgactt ggcagaaaca
    45481 gtggccaata ttcgtcgcta ccagatgttt ggcatcaatc tgtccatgcc ctataaggag
    45541 caggtgattc cttatttgga tgagctaagc gatgaagcgc gcttgattgg tgcggttaat
    45601 acggttgtca atgagaatgg caatttaatt ggatataata cagatggcaa gggatttttt
    45661 aagtgcttgc cttcttttac aatttcaggt aaaaagatga ccctgctggg tgcaggtggt
    45721 gcggctaaat caatcttggc acaggctatt ttggatggcg tcagtcagat ttcggtcttt
    45781 gttcgttccg tttctatgga aaaaacaaga ccttacctag acaagttaca ggagcagaca
    45841 ggctttaaag tggatttgtg tgctttagaa tatgtttctg aactgcaagc aaggattgcc
    45901 gagtcggatt tgctagttaa tgccaccagt gtgggcatgg atggccaatc ctctcctgtt
    45961 cctgaaaaca tagtcttacc agaaactctt ttagttgcag atatcatata ccaacccttt
    46021 gaaacaccgt ttttgaaatg ggctagaagt cagggcaatc cagcagtcaa tggtctggga
    46081 atgttgctct atcaagctgc agaagctttt caactgtgga caggcaagga aatgccgaca
    46141 gaagagattt ggcagtcttt aacagaaaaa taccaataaa gaaagggaga ctctcctatg
    46201 aaaatcagaa tcgatattcc tcatcatcct tatgatattc agattgaaaa aggttgtatg
    46261 gcccaggctg gtcagtggtt gcgagaactc tggcaaccgc aaaaggtagt cattgtgaca
    46321 gataaccatg tagcctctct ctatgcagag aaggtcaagc tcagcctaga agatgctggt
    46381 tttcaggtag ctgtttttga tttcttagaa ggtgaagaaa gaaagaattt aactactgtt
    46441 cagaaagtct atgaatttct agtcaagcaa ggtctgactc gtagcgatgg aatcgttgct
    46501 cttggtggtg gcgttgttgg ggacctggct ggctttgtag cctctaccta tatgcggggt
    46561 attcactttg ttcagattcc gactagtttg acagctcagg ttgattcttc tatcggtgga
    46621 aagacaggcg ttaacacacc atttgctaaa aatatggtgg ggacctttgc ccaaccagat
    46681 ggggttctga ttgatccact tgttcttgaa accctcggaa aaagagagtt gattgaaggg
    46741 atgggtgaag ttatcaagta tggcttgatt gaggatccag aactgtgggc tctcttgacg
    46801 ggactgaatg gttctgttga gagtattttg gaacatgcag agaccttgat tgaacattct
    46861 tgtcaggtga agcgcaagat ggtggttgaa gatgagttgg acaatggtat tcgtctttac
    46921 ctcaattttg gccacactat tggccatgcc atcgaagcga ctgccggtta tggcaaggtc
    46981 atgcatggag aggctgttgc catgggaatg gtacagattt ccaagattgc tgaggaaaaa
    47041 ggcctcatgc cagctggcat tacccaatct atcacagaga tgtgtcagaa attcggcttg
    47101 cctgttgact atgaaaattg ggaagttgac aagctttatc aggctcttac tcatgacaag
    47161 aaagcgcgtg gcaacacctt gaaattggtc ttggtgccag agcttggttc agcgatcatt
    47221 cacccagttt ctctggaaga gatgaaagac tacttggtaa aataaggaga gtgtatgaga
    47281 tatttaactg caggagaatc acacggcccc cgtctaacag ctattattga tggaattcca
    47341 gctggacttc cattgacagc tgaggatatc aatgaggacc ttagacgccg tcagggtggc
    47401 tacggtcgtg gtggtcgtat gaagattgag aatgaccagg ttgtctttac ttcgggcgtt
    47461 cgccacggga agacgacagg ggcgcctatt actatggatg tcatcaataa ggaccaccag
    47521 aaatggctgg acatcatgtc tgcggaggac attgaagacc gtcttaaaag caagcggaaa
    47581 attactcatc ctcgcccagg tcatgccgat ttggttgggg ggattaagta ccgttttgat
    47641 gatttgcgaa attctttgga gcgttcatca gctcgtgaaa ccaccatgcg ggtggcagtt
    47701 ggtgcagtag ccaaacgcct cttggctgag ttggatatgg agattgccaa ccatgtcgtg
    47761 gtctttggtg gcaaggaaat cgatgttcct gaaaatctga cagtcgctga aattaagcaa
    47821 agagctgccc agtctgaagt ttctattgtc aaccaagaac gagaacagga aatcaaggac
    47881 tatattgacc aaatcaaacg tgatggtgat accatcggtg gggttgtgga gacagtcgtc
    47941 ggaggcgttc cagttggtct tggttcctat gtccaatggg atagaaaatt ggatgcaaga
    48001 ttggctcaag ctgttgtatc tatcaatgcc tttaaagggg tggaatttgg tcttggcttt
    48061 gaggctggtt atcgtaaagg cagccaagtt atggatgaaa ttctctggtc taaagaagac
    48121 ggttatactc gccgtaccaa taatctaggt ggttttgaag gtggtatgac taatgggcaa
    48181 cccatcgttg ttcgtggggt catgaaaccc attcctactc tttataaacc tcttatgagt
    48241 gtggatatcg aaacccacga accttacaag gcaaccgtgg agagaagtga tccgactgct
    48301 cttccagctg caggaatggt catggaagca gttgtagcaa cggttctggc gcaagaaatc
    48361 ctcgaaaaat tctcatcaga taatcttgag gaactaaaag aagcggtagc caaacaccga
    48421 gactatacaa agaactatta aggagttcct atggcaaaaa caatctatat cgcaggtctt
    48481 gggttgattg gagcctctat ggcacttggt atcaaacgcg atcatccaga ttatgaaatt
    48541 ttaggttata atcgtagtca agcttcgaga gatatcgcct tgaaagaagg catgattgac
    48601 cgtgcaacgg atgattttgc tagttttgct cctttggcag atgtcattat cctcagcttg
    48661 ccaatcaaac aaactattgc tttcattaag gagttggcca atttggattt gcgagaaggc
    48721 gttattattt cagatgctgg ttcgaccaag tcaaccattg tggatgcggc ggagcagtat
    48781 ttggctggca agtctgttcg ctttgtcggg gcccatccca tggctggtag tcacaagaca
    48841 ggggctgctt cggcagatgt caatcttttt gaaaatgcct attatatctt tacaccttca
    48901 agcctgacaa gtcaggacac gcttaaggaa atgaaggatc tgctttcagg tcttcatgct
    48961 cgttttatcg agattgatgc caaggagcat gatcgtgtca cttctcagat tagccatttt
    49021 cctcatattt tggcttctag tctcatggag cagactgcgg tctatgctca agagcatgag
    49081 atggcaaggc gctttgcggc aggtggtttt cgagatatga cccgaattgc ggaaagcgag
    49141 ccaggaatgt ggacctccat tctcttgtcc aatagcgaga tcattctgga tagaattgag
    49201 gatttcaagg aacgtttgga agcgattggt caggccatta gtaagggaga tgaagagcaa
    49261 atttggaact tttttaacca agcgcgtgaa caacgccaga ccatggaaat ccataagcgt
    49321 ggtggtgtgg atagctctta cgacctctat gttgacgttc ctgatgaaga agatgtcatc
    49381 ctgcggattt tggaactgct acgtggaact tccttggtta atatccacat caacgaggaa
    49441 aatcgtgagg atattcacgg aatcctacaa atttcattta aaaatgctca agacttggaa
    49501 agagctgagc atctcataac agaaaatact gactatacag tcgtcatcaa ataaggagaa
    49561 gaacatgtca aatatttacg atagtgcaaa cgaactcagt cgcggtctac gcggattacc
    49621 agaatacaag gctgttaaag cagctaaaga tgcgattgca gcagatgctg aggcaagcaa
    49681 aatctttaca gattatcttg cctttcaaga ggaaattcaa aaactagcac agacaggtca
    49741 aatgccagat gcgtccttcc aagctaagat ggaaggcttt ggtaaacaga ttcaaggaaa
    49801 tagcctcttg tcagaattct ttaccaagca acaacaattg gccatttacc tttctgacat
    49861 tgaaaaaatt gtttttgaac cagtttcaga attgctgaaa taagaaaaga actatcctaa
    49921 agtcaggaat ttttaaggaa tttctggctt tttatgataa aataggtaaa agtattgcaa
    49981 gtatgaggtc cagtatgaaa ctaaaaacaa acattcgcca tttacatggt agtatccgcg
    50041 tcccaggtga caagtctatc agccaccgtt ccattatctt tggaagtttg gctgagggtg
    50101 agaccaaggt ttatgatatt ctgcgaggcg aagacgttct ttcgaccatg caggtttttc
    50161 gtgaccttgg tgttgaaatt gaggataaag atggggttat taccattcaa ggtgtaggca
    50221 tggctggctt aaaagcgccg caaaatgccc ttaatatggg aaattctggc acctcgattc
    50281 gcctgatttc aggtgtcctt gctggtgcag atttcgaagt agagatgttt ggagatgata
    50341 gtctttccaa acgtcctatg gaccgtgtga cccttccact gaaaaaaatg ggcgtcagca
    50401 tttcagggca aactgaacga gacttgcctc cccttcgctt aaaagggacg aaaaacctaa
    50461 gccctattca ttatgagttg ccaattgcct ctgcccaagt caagtcagcc ttgatgtttg
    50521 cagccttaca agctaagggg gagtcagtta ttatcgaaaa agaatacacc cgtaatcata
    50581 ctgaagatat gttgcaacaa tttggtggtc atttaagtgt ggatggtaag aaaatcacag
    50641 tccaagggcc acaaaaattg acaggacaga aggtggtcgt accaggagat atttccagtg
    50701 cagccttttg gttagtcgca ggtttgattg ctccaaattc tcgtctagtg ctgcagaatg
    50761 tggggatcaa cgaaactcgc accggtatta ttgatgtcat tcgtgccatg ggtggaaaat
    50821 tggaaataac tgaaatcgat ccagtcgcta aatctgcaac cttgattgtt gagtcttctg
    50881 acttgaaagg aacagagatt tgtggcgctt tgattccacg tttgattgat gaattgccta
    50941 ttattgccct acttgcgacc caagcccaag gtgtaacagt tattaaagat gctgaggagc
    51001 tcaaggtcaa ggaaacagac cgtattcagg ttgtggcaga cgccttaaat agtatgggag
    51061 cagatattac tcctacggca gatgggatga ttatcaaagg aaaatcagct cttcacggtg
    51121 ctagagtcaa tacgtttggt gaccaccgta tcggcatgat gacagctatc gcagccctat
    51181 tggttgcaga tggagaggtg gagcttgacc gtgcagaagc catcaatacc agctatccta
    51241 gtttctttga tgatttggag agcttgattc atggctaagg tgttattagg gtttatgggg
    51301 gctggaaaat caactattgc aagaggcttg gaccctaatt accttgatat ggatgctctg
    51361 attgagaagc gcctaggtat gtccattgcg aattttttcg ctgaaaaggg agaatcagcc
    51421 tttcgtcagg tagaatcaga agtcctagct gatttactac aaacagacca agtcgtgtca
    51481 actggaggag gagtggttat ttctcagaga aatcgtgact tactcaagac taatacagat
    51541 aacatctacc tgaaagcaga ttttgaaacc ctctacctac gtatcgtagc tgataaggac
    51601 aatcagcgac cgctttttct aaataatagc aaggaagaac tagtagctat ttttcaagaa
    51661 agacaggctt ggtatgagga agtggctagt cgggttttgg atgtgaccaa gctaagccca
    51721 gaggaaatta tagaggaact aagatgaaaa ttgcttatct aggtcccaaa ggatcatttt
    51781 cacaccacgt tgtgcagaca gcttttcctc atgaggaatt gcaggctttt gccaacatta
    51841 cagatgttat caaggcttat gagcaaggat tagtggacta ttctgtggtg ccagttgaaa
    51901 attctattga gggtagtgtt catgaaacct tggactatct ttttcatcag gctcacatcc
    51961 aagcagtagc agaaatcgtt cagcctattc atcagcagtt gatggtggtt ccaggccata
    52021 ctaagattga aaagattttt tcacatccac aggccttggc tcaaggaaag aaattcatcg
    52081 atgaacaata tccagaggct caaatcgagg taacagctag tacagcttat gcggcccgtt
    52141 ttatttccga acatccagac cagccctttg cagcagttgc acctagaagt tctgctgaag
    52201 aatatggatt ggaactgatt gccgaggata ttcaggaaat ggaagccaat ttcacacgtt
    52261 tctgggttct aggagctgaa aagcctagta ttcccttgca agcacaaact gaaaagatga
    52321 gtttggcctt gacattacct gacaaccttc caggtgcact ttataaggcc ctgtcgacct
    52381 ttgcttggcg aggaattgac ttgacaaaaa ttgaaagtcg tccactcaag acagcactgg
    52441 gtgaatactt tttcattatc gatgtggatt ataccgataa ggacttggtc cactttgccc
    52501 aaaaagaatt agaagcgatt ggaatccagt ataaaattct gggtgcctat cctatttatc
    52561 caatatcaga ccatggaaag gagagaagat gagtaaagaa aatcccttaa gtcatcatga
    52621 gcagttgcgt tatgattatt tgctaaaaaa tattcactac ctcaatgaga gagaaaaaaa
    52681 tgagtttgcc tatttgcaag aaaagctaac tcttgctagg agaaatagta gctctagctt
    52741 ggaacaagaa agagaagagc aggttgactt accaagttat gcgaaccgga gtcgctcaca
    52801 atccaaatca caagcactct cttcccctcc aaaaaagaaa agacggaagc tccgtcttaa
    52861 acgaattttt atggtgattt tttcactttt ggtctgtgtg gctttggcca tggtattcat
    52921 gtttttgcgt ggttaccaag atgctagcgc aaagaaaact gctgatgccc gggcagctca
    52981 agtagaagtc tttaatggtc aggacactag agatggagtt aatattttaa tcatgggtac
    53041 tgatggtcga atcggccaga acagtgttga gacacgaact gactctatta tggtattaaa
    53101 tgtcgggggc tcagataaga aaatgaagct agtcagtttc atgcgtgata atttggtcta
    53161 tatagatggt tatagtcaag tgattaacgg tagaaaacag acagataaca agttaaacgt
    53221 agcctacgag ttaggagaac aagaggggca aaaaggggca gaaatggttc gccaagtctt
    53281 gaaagataat tttgacttgg acattaagta ctacgccttg gttgatttcc aggcctttgc
    53341 cacagcgatt gacacacttt tccctgatgg ggtgacgatt gatgctcaat tttcaacatt
    53401 gaatgggcgt cccctaacag aagctacagt cggagatgat ttatacgcta ccgagactga
    53461 gtctccaacc caaaccatta aagtcggaaa acagcagatg aatggctcga ccctgctcaa
    53521 ttatgctcgt ttccgtgatg atgatgaggc ggattacggc cgtacaaaaa gacagcaaca
    53581 agttttaaca gcaattttag agcaaattaa agatcccact aaacttttca ctggttctga
    53641 agctcttgga aaggtttttg ctatgacctc aaccaacgta ccctatactt tcctcctaac
    53701 aaacggttta tctgttttgg atggagcaaa aaatggtatt gaaaaattga cgattccaga
    53761 actgggtgac tgggtagatg cctatgatgt ttatggaggc ttgggcttgc tggttgatca
    53821 aaacaaatat caaaccaagc tcgctcaaat gggcttgaga taagataata ctcaatgaaa
    53881 atcaaagtgc aaactaggaa gctagccgca ggctgctaaa aacacagttt tgaggttata
    53941 gataagactg acgaagtcag ttacctatac ctacggcaag gtgaagctga cgtgctttga
    54001 agagattttc gaagagtata agacagaaaa atcaaagttt gatagctatt tggatagcag
    54061 tcaggctttg attttttaca gtctgcaata gattttcacc ccttgtttgt ggtataatga
    54121 aacgatacga tagaaagaat aatgaacaat atgactgatt taaaagcaat tcaggctcgt
    54181 agtctggaga tggctgaata ttttgtggcc ttttgtaaag aacatgattt gctctgttat
    54241 ctctgtggcg gaggcgctat tggtaccctt cgaaacaagg gatttattcc ttgggacgac
    54301 gacctagact tttttatgcc tcgtaaagat tatgagaaat tagcagaatt atggcctcgt
    54361 tatgcagatg aacgttattt cttgtcaaag agttacaagg attttgttga tcgtaatctt
    54421 tttattacca ttcgtgacaa ggaaaccacc tgtatcaagc cttatcagca ggatttggat
    54481 ttgccacatg gtctggcctt ggatgttttg cctttggatt attatccgaa agatccagct
    54541 gagcggaaaa aacaggttcg ttgggccttg atttattcac tcttttgtgc gcaaactatt
    54601 ccagaaaagc atggtgctct catgaaatgg ggaagtcgca ttttactggg tttgactcca
    54661 aaatctctcc gttatcgcat ctggaaaaaa gctgagaaag aaatgactaa gtatgatttg
    54721 gctgattgtg atggcattac agaattatgc tcaggtcctg gctacatgag aaacaagtac
    54781 ccaatcacat cttttgaaga caatcttttc ttgccatttg agggaacaga gatgcctatt
    54841 ccaatcggct atgatgtcta tctcagaact gcttttgggg attatatgac gcctccacca
    54901 gcagacaagc aggtaccgca tcatgatgct gtcatcgctg atatggataa gtcttataca
    54961 gaatacaagg gagaatatgg tggctaagaa aaaaatctta ttttttatgt ggtctttttc
    55021 tcttggaggt ggtgcagaga agattctatc aaccattgtt tcaaatctgg atccagaaaa
    55081 gtatgatatt gatattcttg aaatggagca ctttgacaag ggatatgaat ctgttccaaa
    55141 gcatgtacgc attttaaaat cccttcaaga ttatcgccaa accagatggt tacgagcttt
    55201 tttgtggaga atgagaattt attttccaag actggctcgt cgtttgcttg taaaagatga
    55261 ttatgatgtt gaagtttctt ttaccattat gaatccacca ctgttgttct ctaaaagaag
    55321 agaagtcaag aagatatctt ggattcatgg aagtattgaa gaacttctta aggatagctc
    55381 taaaagagaa tcacatagaa gccagttgga tgctgcgaat acaattgtag ggatttcaaa
    55441 aaagaccagc aattctatca aggaagttta tccagattat gcttctaaat tacagacaat
    55501 ctacaatgga tatgattttc agactattct agaaaaatct caagagaaga tcgatatcga
    55561 gattgctcct caaagtatct gtactatcgg acggattgag gaaaataagg gttctgaccg
    55621 tgtagtggaa gtgatacgat tattacacca agagggaaaa aactatcatc tctattttat
    55681 cggggctggt gatatggaag aggaactgaa aaaacgagtc aaagagtatg ggattgagga
    55741 ctatgtacat ttccttggtt atcaaaaaaa tccttatcag tatttatctc agacgaaagt
    55801 tctcttgtct atgtctaaac aagaaggttt tcctggagtg tatgtggagg ccttgagtct
    55861 gggactccct tttatctcta cggacgttgg aggggctgag gaattatccc aagaaggacg
    55921 atttggacaa atcattgaga gcaatcaaga ggcagctcag gcgattacta attacatgac
    55981 ttctgcctca aactttgatg tcgatgaggc tagccaattc attcaacaat ttacaattac
    56041 aaaacaaatc gaacaagtag aaaaactatt agaggagtag catggaaact gcattaatta
    56101 gtgtgattgt gccagtctat aatgtggcgc agtacctaga aaaatcgata gcttccattc
    56161 agaagcagat ctatcaaaat ctggaaatta ttcttgttga tgatggtgca acagatgaaa
    56221 gtggtcgctt gtgtgactca atcgctgaac aagatgacag ggtgtcagtg cttcataaaa
    56281 agaacgaagg attgtcgcaa gcacgaaatg atgggatgaa gcaggctcac ggggattatc
    56341 tgatttttat tgactcagat gattatatcc atccagaaat gattcagagc ttatatgagc
    56401 aattagttca agaagatgcg gatgtttcaa gctgtggtgt catgaatgtc tatgctaatg
    56461 atgaaagccc acagtcagcc aatcaggatg actattttgt ctgtgattct caaacatttc
    56521 taaaggaata cctcataggt gaaaaaatac ctgggacgat ttgcaataag ctaatcaaga
    56581 gacagattgc aactgcccta tcctttccta aggggttgat ttacgaagat gcctattacc
    56641 attttgattt aatcaagttg gccaagaagt atgtggttaa tactaaaccc tattattact
    56701 atttccatag aggggatagt attacgacca aaccctatgc agagaaggat ttagcctata
    56761 ttgatatcta ccaaaagttt tataatgaag ttgtgaaaaa ctatcctgac ttgaaagagg
    56821 tcgctttttt cagattggcc tatgcccact tctttattct ggataagatg ttgctagatg
    56881 atcagtataa acagtttgaa gcctattctc agattcatcg ttttttaaaa ggccatgcct
    56941 ttgctatttc taggaatcca attttccgta aggggagaag aattagtgct ttggccctat
    57001 tcataaatat ttccttatat cgattcttat tactgaaaaa tattgaaaaa tctaaaaaat
    57061 tacattagaa cgggggtgac caagtgattg atgggaaacg attattattt agtttgacca
    57121 tagtcagtta tgccttgacg ctagtaagtg gaattgtgta tctgtttaat aataataatg
    57181 ttagcttact ttctacttta ttgttcttgt tggttagtag cttaattgct tgttggaatg
    57241 atatcaagta ttacttaatc cattttattt tctatttaac catttttgta tttctggtat
    57301 caagaccgac cattgattat tttagggatg gtgctttgga tacctatcat ccaatagcct
    57361 atcgttttgc ctttatagtt gtcatggttt cgattctggg cttgaccaca ggaggcattc
    57421 tggctcgtta cttcatagct aggaagaaaa taaaagtagc aaatatagga aattctctaa
    57481 aagaggttta tatcaagcgg ttacgctttg tatcactagg agtttttctt ctaacctatc
    57541 ctttctattt cattcggtta tttgaacggc tcttgtatcg tttgcagact tcctactatg
    57601 cctactatgc aaattttgaa agtaaactgc cttattttac ctacattttg tctaccttta
    57661 cggtctatgc aatgtgtatg tatctggcaa ccaagccaaa gaaattgcag gccacagcag
    57721 tgcttgtctc ctttattgca gctaatacta ttcatttggc aattgggaca cgaaatccct
    57781 ttattttaag tattttattt gcttttgttt attactttat gcgggagcaa actgaaaaag
    57841 gaaaatggat tgggtttaaa gaaaagttag cgatttttgt aggttctcct attctcatgt
    57901 tagcgatggg agtactcaat tatgtacggg ataatgtcca agtttcccat acaggtttct
    57961 gggatatctt acttgacttt atctataaac aagggactag ttttggtgtt ctggctcgag
    58021 gttttctatt taacagtagc ctcccttacc gagatttccg taattttact tttggtcctg
    58081 ttcttgatta ttttgcaagg gggagtttgg gagccatttt cggaggaaaa gcctttgaac
    58141 atacaaccaa tagtgtggaa ctagctattg atagtaatag ttatgcccac aatctatcct
    58201 atcttgtctt gaacaaggaa tacctgaaag ggcatggtat cggaagtagt tatatcatgg
    58261 agttgtatac cgactatggt atgattggag tctttctgct tagtttctta ctcggcgtat
    58321 tatttatagc catgctgcaa gtagcctatc gctcaaggac aatcctattt gctttatccc
    58381 tactcatctt gaataatcta ttctttatgc caagaagcag cttttcagaa agtttcttca
    58441 atttatttac aatgcaattc tggggaattg ttcttgtgat tatatttata gcaaaaatgc
    58501 ttacaaagga aaactagtat ctactaaaca aaggagaaaa aaatcatgtt tgaacattat
    58561 tcagtagctg atttgtttgc aaatctttat aaaaagcgaa aagcaaatat tttagctctc
    58621 atcgctttat ttgctctcat tgctgtacca tttacaatta aagcagttag gaataaaaac
    58681 actgtcaaag atacaacaag ttattcaact tatcttatct ataaaatcac tcctccaaaa
    58741 gagtcggcca aaacgatttt gaatcatcaa attggtggtt atagtgattt ttatgggaaa
    58801 ttgattgatg gtaatttgaa tggagcttat cttttcaatg atgtagaacc cagtgagttg
    58861 aaaaaaattg ccagtgaatt agacacgaca gaaacaacct tgaaaaattc aacgaatgac
    58921 tattggtgga aaaaattgac cgtctactat atgattgacg atgcaggggt tggtgtgaaa
    58981 attttgacat caagtaaaga tgccaatgac ttgttagaga aaaaaattga tgggttgatt
    59041 gagaaattta aacatgccta tgcaaatgtg aaaattgaaa aactggaaac catcaactct
    59101 aaagaattga acgcaaatgg tgaaacagcg cttggcttaa atgtgaaaaa tctgattctt
    59161 cgtttagttg ttattggagt ggtttgtgtg attttggttg tgatgggaaa tgtgttagtt
    59221 tatctcttta atccaacaat caatagagta ggtgattttt ctcagtatca aattgatttt
    59281 gtaacagaga ttacaacaat tgctaaccta gcagatgttt tgtcatacaa aaatactgga
    59341 caggaattga ccatcgttag ctcaaataaa gctatcctag ataaattgaa acagagtcaa
    59401 gaagctttaa aaggaatgca ttttgtagat ttacaggatg tatcatctct tttggaaaga
    59461 gatacagtcc ttcttgttga agagtacgga gtgactcgtt ataagaaatt tgagcaaagt
    59521 cttcaaattc tcagaaactt aaatcgttct atcctcggtg tagcaacctt taaattataa
    59581 gtattctgat gtataaggtc ttcaaagtcg gctaagagcc gattttgaag gctttttcta
    59641 tctgtctgca gaaattttct tttgataaaa tcgtaaaaat ctagtataat agatagaact
    59701 gaaagtatga ggttactagc aatgaaaatg aaacaaatta gtgatacaac tttaaaaatc
    59761 acgatatctt tagaggattt gatggatcgt ggaatggaga ttgctgactt tctcgttcct
    59821 caagaaaaaa cagaagagtt cttttatgct atcttggatg agctagagat gcctgatagc
    59881 tttctggata caggcatgtt gagcttccgt gtgactccaa aacctgataa ggtagatgtc
    59941 tttgtgacca agtcaaagat tgaccaaaat ctagattttg aagacttatc ggatttgcca
    60001 gatatggaag aattggctca aatgtctcca gatgaattta tcaaaaccct ggaaaaaagc
    60061 atcgcagaca aaaccaagga tgatatcgaa gccattcaat ctcttgagca agttgaagcc
    60121 aaggaagaag aacaagagca ggctgaacaa gaagctgaga gtaagaaaga accttacatc
    60181 tactacatcc tttcttttgc taagttggct gacttggtag cttttgccaa gacagtgact
    60241 tttgaaatgg aaacttctga actctacaaa atgaacgagc gctattattt gaccatttta
    60301 gtggatattg aaaatcatcc aagcccatat ccagcttggc tgttggcccg tatgcgcgag
    60361 tttgcagagg atagtgatat cagtcgctca gtcttacaag agtatggtca agttttgatg
    60421 agtcacgatg cagtgctcaa tctgcaaaaa atcggctaat cttttctgga aagctatttt
    60481 cagattttaa gaagagcgaa tcgtctgatt cgttttttct ttttatactg aaatagtgat
    60541 ttactataat aggaattttc acaaaattct gttataatgg ctatattaga aaatttcgag
    60601 gagataaaga tgacagttaa aattgcttta ctaggatttg gtaccgttgc aagtggtgtg
    60661 cctttcctcc taaaggaaaa tggaggaaaa atcaatcaat cagcacattc agatatcaaa
    60721 gttgctaagg tattggtcaa ggatgaagat gaaaaaaatc gcttgcttgc agcagggaat
    60781 gactttaact ttgtaaccaa tgtggatgat attttatcag accaggatat tactatcgta
    60841 gtggaattga tggggcgtat tgagcctgct aaaaccttta tcactcgtgc cttggaagct
    60901 ggaaaacacg ttgttactgc taacaaggac cttttagctg tccatggcgc agaattgcta
    60961 gaaatcgctc aagctaacaa ggtagcactt tactacgaag cagcagttgc tggtgggatt
    61021 ccaattcttc gtactttagc aaattccttg gcttctgata aaattacgcg cgtgcttgga
    61081 gtagtcaacg gaacttccaa cttcatggtg accaagatgg tggaagaagg ctggtcttac
    61141 gatgatgctc ttgcggaagc acaacgtcta ggatttgcag aaagcgatcc gacgaatgac
    61201 gtagatggga ttgatgcagc ctacaagatg gttattttga gccaatttgc ctttggcatg
    61261 aagattgcct ttgatgatgt agtccacaag ggaatccgca atatcacacc agaagacgta
    61321 gctgtagctc aagagcttgg ttacgtagtg aaattggttg gttctattga ggaaacttct
    61381 tcaggtattg ctgcagaagt gactccaacc ttcctaccta aagcgcaccc acttgctagt
    61441 gtgaatggcg taatgaacgc tgtctttgta gaatctatcg gtattggtga gtctatgtac
    61501 tacggaccag gtgcgggtca aaaaccaact gcaacaagtg ttgtagctga tattgtccgt
    61561 atcgttcgtc gtttgaatga tggtactatt ggcaaagact tcaacgaata tagccgtgac
    61621 ttggtcttgg caaatcctga agatgtcaaa gcaaactact atttctcaat cttggctcca
    61681 gactcaaaag gtcaggtctt gaagttggct gaaatcttca atgctcaaga tatttccttt
    61741 aagcaaatcc ttcaagatgg caaagagggt gacaaggcgc gtgtcgttat catcacacac
    61801 aagattaata aagcccagct tgaaaatgtc tcagctgaat tgaagaaggt ttcagaattc
    61861 gacctcttga ataccttcaa ggtgctagga gaataagatg aagattattg tacctgcaac
    61921 cagtgccaat atcgggccag gttttgactc ggtcggtgta gctgtaacca agtatcttca
    61981 aattgaggtc tgcgaagaac gagatgagtg gctgattgaa caccagattg gcaaatggat
    62041 tccacatgat gagcgtaatc tcttgctcaa aatcgcttta caaattgtac cagacttgca
    62101 accaagacgc ttgaaaatga ccagtgatgt ccctttggcg cgcggtttgg gttcttccag
    62161 ctcggttatc gttgctggga ttgaactagc caaccaactg ggtcaactca acttatcaga
    62221 ccatgaaaaa ttgcagttag cgaccaagat tgaagggcat cctgacaatg tggctccagc
    62281 catttatggt aatctcgtta ttgcaagttc tgttgaaggg caagtctctg ctatcgtagc
    62341 agactttcca gagtgtgatt ttctagctta cattccaaac tatgaattac gtactcgcga
    62401 cagccgtagt gtcttgccta aaaaattgtc ttataaggaa gctgttgctg caagttctat
    62461 cgccaatgta gcggttgctg ccttgttggc aggagacatg gtgaccgctg ggcaagcaat
    62521 cgagggagac ctcttccatg agcgctatcg tcaggacttg gtaagagaat ttgcgatgat
    62581 taagcaagtg accaaagaaa atggggccta tgcaacctac ctttctggtg ctgggccgac
    62641 agttatggtt ctggcttctc atgacaagat gccaacaatt aaggcagaat tggaaaagca
    62701 acctttcaaa ggaaaactgc atgacttgag agttgatacc caaggtgtcc gtgtagaagc
    62761 aaaataaaga atagaagata ggatggggaa actcttgacc agagggtttc atatcctttt
    62821 tgtgaaaaga agtttatact caatgaaaat caaagagcaa actaggaagc tagccgcagg
    62881 ctgctcaaaa cagtgttttg aggttgcaga tagaactgac gaagtcagta acatatatac
    62941 ggtaaggtga cgctgacgtg gtttgaagag attttcgaag agtattagtt aaaaacgtga
    63001 taaaggagaa ataaagatgg cagaaattta tctagcaggt ggttgttttt ggggcctaga
    63061 ggaatatttt tcacgcattt ctggagtgct agaaaccagt gttggctacg ctaatggtca
    63121 agtcgaaacg accaattacc agttgatcaa ggaaacagac catgcagaaa cggtccaagt
    63181 gatttacgat gagaaggaag tgtcactcag agagatttta ctttattatt tccgagttat
    63241 cgatcctcta tctatcaatc aacaagggaa tgaccgtggt cgccaatatc gaactgggat
    63301 ttattatcag gatgaagcag atttgccagc tatctacaca gtggtacagg agcaggaacg
    63361 catgctgggt cgaaagattg cagtagaagt ggagcaatta cgccactaca ttctggctga
    63421 agactaccac caagattatc tcaggaagaa tccttcaggt tactgtcata tcgatgtgac
    63481 cgatgctgat aagccattga ttgatgcagc aaactatgaa aagcctagtc aagaggtgtt
    63541 gaaggccagt ctatctgaag agtcttatcg tgtcacacaa gaagctgcta cagaggctcc
    63601 atttaccaat gcctatgacc aaacctttga agaggggatt tatgtagata ttacgacagg
    63661 tgagccactc ttttttgcca aggataagtt tgcttcaggt tgtggttggc caagttttag
    63721 ccgtccgatt tccaaagagt tgattcatta ttacaaggat ctgagccatg gaatggagcg
    63781 aattgaagtt cgttctcgtt caggcagtgc tcacttgggt catgttttca cagatggacc
    63841 gcgggagtta ggcggcctcc gttactgtat caattctgct tctttacgct ttgtggccaa
    63901 ggatgagatg gaaaaagcag gatatggcta tctattgcct tacttaaaca aataaaacag
    63961 agagtggggc ttcccacttt cttcatttct agaatatgaa tagaagggat ttatgaaaca
    64021 cctattatct tacttcaaac cctacatcaa ggaatcaatt ttagccccct tgttcaagct
    64081 gttagaagct gtttttgagc tcttggttcc catggtgatt gctgggattg ttgaccaatc
    64141 tttacctcag ggagatcaag gtcatctctg gatgcagatt ggcctgctcc ttatctttgc
    64201 agtaattggc gttttagtgg ccttgatagc tcaattttac tcagcaaagg cagcagtagg
    64261 ttttgctaag gaattgacaa acgatcttta tcgtcatatt ctttccttgc ccaaggacag
    64321 cagagaccgt ctgacaacat ctagtttggt cactcgcttg acttcggata cctaccagat
    64381 tcagactggt atcaatcaat tcctgcgtct ctttttgcga gcgcccatta tcgtttttgg
    64441 tgccattttt atggcttatc gaatctcaac tgagttgact ttctggttct tagtcatggt
    64501 tgccattttg accattgtca ttgtagggtt atctcgattg gtcaatcctc tctacagtag
    64561 tctcagaaag aaaacggacc aactggttca ggaaacgcgc cagcaattgc aagggatgcg
    64621 ggttattcgt gcttttggtc aagaaaaacg agagttacag atttttcaaa cccttaacca
    64681 agtttatgct agattacaag aaaagacagg tttctggtct agtttattaa cacctctgac
    64741 ctatctgatt gtcaatggaa ctcttctcgt tattatctgg caaggctata tttcaattca
    64801 aggaggagtg ctcagtcaag gtgctctcat tgctcttatc aattacctct tacagatttt
    64861 ggtggaattg gtcaagctag ccatgttgat caattccctc aaccagtcct atatctcagt
    64921 caagcgaatc gaggaagtct ttgttgaggc tccagaggat atccattcag agttagaaca
    64981 aaagcaagct accagagata aggttttaca agtccaagaa ttgactttta cctatcctga
    65041 tgcggcccag ccttctctga gatacatttc ctttgatatg actcaaggac aaattctagg
    65101 tatcatcggg ggaactggtt ctggtaaatc aagcttggtg caactcttac ttggacttta
    65161 tccagtagac aaggggaaca ttgaccttta tcaaaatgga cgtagtcctc ttaatttgga
    65221 gcagtggcgg tcttggattg cctatgtacc tcaaaaggtc gaactcttta aaggaaccat
    65281 tcgttccaac ttgactctag gtttcaatca agaagtatct gaccaggaac tctggcaggc
    65341 cttggagatt gcgcaagcta aggattttgt cagtgaaaag gaaggactct tggatgctct
    65401 agttgaggca ggggggcgaa atttctcagg tggacaaaaa caaagattgt ctatcgcccg
    65461 agcagtcttg cgccaagctc cgtttctcat cctagatgat gcaacctcgg cactggatac
    65521 cattacagag tccaagctct tgaaagctat tagagaaaat tttccaaaca cgagcttaat
    65581 tttgatctct caacgaacct caactttaca gatggcggac cagattctcc tcttggaaaa
    65641 aggtgagttg ctagctgttg gcaagcacga tgacttgatg aaatccagcc aagtctattg
    65701 tgaaatcaat gcatcccaac atggaaagga ggactagaat gaaacgacaa actgtaaacc
    65761 agacgctcaa acgtttagcc gtagatttag caagccatcc tttcctcctt ttcctagcct
    65821 ttctaggaac tattgctcaa gttggcttat caatttacct acctattctg attgggcagg
    65881 tcattgacca agtcctagtg gctggttcat caccagtttt ttggcagatt tttctccaga
    65941 tgctcttggt ggtaatagga aatactctgg tacaatgggc caatcctctc ctctataatc
    66001 gtctaatctt ctcttatacc agagatttac gggagcgaat catccataag ctccatcgtt
    66061 taccgattgc ctttgtagat aggcaaggta gtggagagat ggttagtcgt gtaaccacgg
    66121 acatcgaaca gttggcagct ggcttgacca tgatttttaa ccaatttttc attggtgttt
    66181 tgatgatttt ggtcagtatt ctagccatgc tccaaattca tctcctcatg actctcttag
    66241 tcttgctgtt gacgccactg tccatggtga tttcacgctt tattgccaag aaatcctatc
    66301 atctcttcca gaagcaaaca gagacgaggg gaattcagac tcagttgatt gaagaatcgc
    66361 ttagtcagca gactataatc cagtccttca atgctcaaac agaatttatc caaagattgc
    66421 gtgaggctca tgacaactac tcaggctatt ctcagtcagc catcttttat tcttcaacgg
    66481 tcaatccttc gactcgcttt gtaaatgcac tcatttatgc ccttttagct ggagtaggag
    66541 cttatcgtat catgatgggt tcagccttga ccgtcggtcg tttagtgact tttttgaact
    66601 atgttcagca atacaccaag ccctttaacg atatttcttc agtgctagct gagttgcaaa
    66661 gtgctctggc ttgcgtagag cgtatctatg gagtcttaga tagccctgaa gtggctgaaa
    66721 caggtaagga agtcttgacg accagtgacc aagttaaggg agctatttcc tttaaacatg
    66781 tctcttttgg ctaccatcct gaaaaaattt tgattaagga cttgtctatc gatattccag
    66841 ctggtagtaa ggtagccatc gttggtccga caggtgctgg aaaatcaact cttatcaatc
    66901 tccttatgcg tttttatccc attagctcgg gagatatctt gctggatggg caatccattt
    66961 atgattatac acgagtatca ttgagacagc agtttggtat ggtgcttcaa gaaacctggc
    67021 tcacacaagg gaccattcat gataatattg cctttggcaa tcctgaagcc agtcgagagc
    67081 aagtaattgc tgctgccaaa gcagctaatg cagacttttt catccaacag ttgccacagg
    67141 gatacgatac caagttggaa aatgctggag aatctctctc tgtcggccaa gctcagctct
    67201 tgaccatagc ccgagtcttt ctggctattc caaagattct tatcttagac gaggcaactt
    67261 cttccattga tacacggaca gaagtgctgg tacaggatgc ctttgcaaaa ctcatgaagg
    67321 gccgcacaag tttcatcatt gctcaccgtt tgtcaaccat tcaggatgcg gatttaattc
    67381 ttgtcttagt agatggtgat attgttgaat atggtaacca tcaagaactc atggatagaa
    67441 agggtaagta ttaccaaatg caaaaagctg cggcttttag ttctgaataa gccattctct
    67501 tttgaaagtt tatggacgaa aaaagttgcc ttcgagtgac ttttttgtta caatagctag
    67561 aaaaattgtt cactgtaata ctcaatgaaa atcaaagagc aaactaggaa gctagccgta
    67621 ggttgctcaa agcacagctt tgaggttgta gataagactg acgaagtcag ttcaaaacac
    67681 tgttttgagg ttgcagatag aactgacgaa gtcagctcaa aacactgttt tgaggttgca
    67741 gatagaactg acgaagtcag taaccacacc tacggcaaag tgaatctgaa gtggtttgaa
    67801 gagagtacaa cttgtctttt agaaaaggag cctataatga aagtctttca gcatgtaaat
    67861 atcgtgactt gtgatcaaga tttccatgtt tatcttgatg gaatcttagc agtcaaggat
    67921 tctcaaatcg tctatgtcgg tcaagataag ccagcgtttt tagagcaagc tgagcagatt
    67981 atagactatc agggagcttg gattatgcct ggtttggtca attgtcacac ccattctgca
    68041 atgacaggtc tgagagggat ccgagatgac agcaatctcc atgaatggct caatgactat
    68101 atttggccag cagaatctga gtttactccc gacatgacta ccaatgcggt caaagaagcc
    68161 ctgacagaga tgctccagtc aggaacaaca acctttaacg atatgtataa tcccaatggt
    68221 gtggatatcc agcaaattta tcaggtggtg aaaacttcca agatgcgttg ttatttttct
    68281 ccgactctct tttcttcaga gacagaaaca actgctgaga ctataagtag aactcgatcc
    68341 atcatagacg aaatcttaaa atataaaaat ccaaatttca aggttatggt agcacctcat
    68401 tctccgtata gctgcagtag agacttgctg gaagcgagtt tggaaatggc aaaagagcta
    68461 aatattccgc tccatgtcca tgtggcggag accaaggagg agtcaggaat tatcctcaaa
    68521 cgatacggca aacgccccct tgcttttctt gaagaactgg gttatttaga tcatccgtcc
    68581 gtatttgctc acggggtcga attaaacgag agagaaattg aacgcttggc atcttctcaa
    68641 gtggctatcg cccacaatcc tatcagtaac ctcaaactgg catcaggaat tgctccaatt
    68701 atccagctcc aaaaagcggg agtagcagtc ggaattgcga ctgactcggt tgcttccaat
    68761 aacaatctag atatgtttga ggaaggaagg actgcagctc ttcttcagaa gatgaaaagt
    68821 ggggatgcca gccagtttcc aatcgaaaca gctctcaagg tactgacaat cgaaggggct
    68881 aaggtccttg gaatggaaaa tcagatagga agtctggaag tcggcaagca agcagatttt
    68941 ctggtcattc aaccacaagg gaaaattcat ctccaacctc aggaaaatat gctgtctcac
    69001 ctggtttatg cagttaaatc tagtgatgta gatgatgttt atatcgccgg agaacaggtt
    69061 gttaagcaag gtcaagtcct gacagtagaa ctttaaaaga aaaattacga aaaattttaa
    69121 aaaaagtttg caaaaatctt gcattctttt tttgactatg ctatacttat atacggttta
    69181 aaaaaactgc ctaagacagt aggggagctc gactcataaa tatcctaccg aggacaaaac
    69241 gtatcatgta aaaagaagcg tattgtactt tcgtgtctag gtttgggcgc gtttttcttt
    69301 ttgaaaaatt ccccaagcaa aataattacg gaggtgaaca cactaatgag tgaagcaatt
    69361 attgctaaaa aagcggaact agttgacgta gtagctgaaa aaatgaaagc tgctgcatct
    69421 atcgtcgttg tagacgctcg tggtttgaca gttgagcaag atacagttct tcgtcgtgag
    69481 cttcgtggaa gcgaagttga gtataaagtt attaaaaact caatcttgcg tcgtgcagct
    69541 gaaaaagctg gtcttgaaga tcttgcatct gtatttgttg gaccatctgc agtagcattt
    69601 tctaatgaag atgttatcgc accagcgaaa atcttgaacg acttttctaa aaacgctgaa
    69661 gcacttgaaa ttaaaggtgg tgcaatcgaa ggcgctgtcg catctaaaga agagattctt
    69721 gcacttgcaa ctcttccaaa ccgcgaagga cttctttcta tgctcctttc tgtacttcaa
    69781 gcaccagtgc gcaacgttgc tcttgcagtc aaagcggttg cagaaagcaa agaagacgcg
    69841 gcttaatctt aagctacaca gcgtagccta gctacgaaaa aaactattat aaaatttaaa
    69901 acttatttgg aggaaataac aatggcattg aacattgaaa acattattgc tgaaattaaa
    69961 gaagcttcaa tccttgaatt gaacgacctt gtaaaagcta tcgaagaaga atttggtgta
    70021 actgcagctg ctcctgtagc tgttgctgca gctgatgcag ctgatgctgg tgctgctaaa
    70081 gattcattcg acgttgaatt gacatctgca ggcgacaaaa aagttggcgt tatcaaagtt
    70141 gtacgtgaaa tcactggtct tggtcttaaa gaagctaaag aacttgttga cggtgcacca
    70201 gcacttgtta aagaaggcgt tgcaactgca gaagctgaag aaatcaaagc taaattggaa
    70261 gaagctggag cttcagttac tcttaaataa tagagtatcg caatttgatt gcggaatccc
    70321 tatttaccag tctttgagag cgataagcga ttgatagaaa ctgataaatt gatttggttt
    70381 cctgccaaaa attctttggc aggatttttg ttttaataaa ctttcggggg tagacactag
    70441 attgtctacc cctttttttg tgtttcggag gtaattatgc aaaaggaagg acagtcatca
    70501 cgtcaattcg tgaagagtca tctcatgact atcatgggag ttgatattgt aaaagcaact
    70561 cagttagttg atgaaatgga acaagtaggt ttaatccgat ttgatgaatt tggaaatgtt
    70621 ggaattttag tcttggaggg acaataatga agcgtattac cgctaatcaa tatcagacat
    70681 cagagcgtta ttataagctc cccaaacttt tatttgagag tgaacggtat aagaatatga
    70741 aactggaggt taaggtggtt tactcagttt taaaagatcg gttggagttg tctttgagca
    70801 aaggttggat tgatgaggat ggggctattt atttgattta ttccaattca aatttgatgg
    70861 cacttttagg ctgttcaaag tcaaaattac tctccatgtg agtttgaagt gatattttta
    70921 gatgattacc ataaaaaaca taactaccca ctattttacg aatcctatct tcaaaacgtt
    70981 atggaattcc ttgaaagtca agacataaag aatggggttg atgcctttgt agatgatcat
    71041 caaaatctcg tttttgtttt atatggacaa ggctatcgag ccgagggaaa agagggaata
    71101 cttacaaccc aagtaactgt aaaagcttat gatgaagaca agaaaccgat taacttcgca
    71161 aatttattag attccttaat ttattagatt ccttaatcgt gtcagaatat caaatggaac
    71221 cgaatctttg ggaggtctcc catgattgat ctctatctaa gtaaaaatag acaaagaaat
    71281 caacttcttt tagatttctt ccaaaactat ggcatagagg tatcttgtca ttcagtttct
    71341 gaaatgacaa aggacaaatt aattgagatg atgagctatt cttcagattg ttttgagttt
    71401 ttatctccca atttattacg atttaagaac cgtgacaatc taagattaac ggatttcgtt
    71461 gagataattt taaaaaatcc tgaactaacc atcagacttc ctcttgcggt ttcaaataag
    71521 cgagtttatc caagtctgaa tttggaagag gctagagctc tattgccaag agatacgaaa
    71581 caattgattt acatggcgca aacacattat ttatctaact aaaggagaag caatatggct
    71641 gaacgatttt gggagaactt gtccattatt ttggctgaaa gaaatatcag ctggattgag
    71701 ttaaccagaa aaatgtttgc gggagagttt cactatccaa gtgaattgaa tcgtttgtat
    71761 caaaagattc gccactagaa gatggaacaa tgaatgcctc aaagtccatg ggtagaaagg
    71821 attgtgcagg tattagattt agattatgaa gatttatttc ggaggtaact atgaaaagaa
    71881 taattccagt ttatatattc caacaagtaa atgtcctatt ggtatctcta tacttattga
    71941 aatttctttg tatcggtgag ttaactatac tacagattct ctatggttcg tcactcattt
    72001 cttttttatg gatgtatggc caacgcaaac aagcgcataa ggtcaatatg aaatctagga
    72061 tgaaatggct tggtgttgaa tttgttagcc tactgattat aagtctatgt tttagtctga
    72121 ttcatgctca aggaagcacg aatcaagcaa acttaattgg ccttcaacat caaattcctt
    72181 ggttttcatt tttattgttc ttaatcaatg cgagtatggt tgaagaattt ctgtatcgag
    72241 aaattttatg gaatttggtc agaaaattag atatcagagt tgctttgaca agtgttttat
    72301 ttgccttagc acatcatcca ggaaccatta tagcttggtg tttgtatgta tcgctgggga
    72361 tgtttttagg gcttgtacgc tacaaattgg acttatgggg cagtatgggg ctacatttgg
    72421 tgtggagcct actagtttat agtttgctgc ttttttaaaa taggtaacct gatttttagg
    72481 taacttctaa aactaacttc cagttttggg agagagatgg aagttacttt gaaaagttac
    72541 ggaaacatta ttttctacgt gacaacattg tatcattgct tgcattttac tgctggagag
    72601 agtataatga aggtggataa agcacttaat cccaaaaatt taaataggag gagttagcta
    72661 tggcagaaga agtattaaat cttcaattag tatctgttca agttgacgaa acagatgaag
    72721 ttgatggaat gcgatttagt acattcagta caaaccgttg cggtaactgg agtgctttta
    72781 gttgggaaaa ttgttaattc atttaaattg taaactttag ggattctctg gagttatgga
    72841 tctcgttcca atatgtgcac gttggaatgt cagtgcttat atggggggaa tccaaaggat
    72901 tctccctttt tattttaata agtctgtcta gctatagata tattaagttt gatagaattt
    72961 cttggagatt ttgttatgga ttataatttc aatttggagc atcctttctt tttcactaat
    73021 aatgattata gtacagatac tagcataaag tactaagtaa gtctgccttt taattggcac
    73081 gaagtaatga ataatgatga gtgggtttat caatacccta ttggaaaatt tgttgaaaga
    73141 caagggtgga aaatacacat tagttcagag tataatagtt cacacgaatt gttacaagat
    73201 gtagcaaaaa tttgccatga aatgcgaatt ccatttaaac atcttagtac agaagacaaa
    73261 tttatcatgc gaaacgggaa attggttagt cgaggatttt ctggtaaatt tattacatgt
    73321 tatccaaatc aaaatgaatt agagtcggtt ttgcaaaggt tagaaagtgc cttaaagcaa
    73381 tataatgggc catatatttt aagcgataaa cgttgggatg aagcaccaat atatctgagg
    73441 tatggtgtgt ttaggccgtc aagggatgat gaaaagaagg ttgttattga tgaattaatt
    73501 gttggcgatg aagttgttaa agatgaacgt ttaccagtat ttaaaattcc aaaaggtata
    73561 gtgccccctg actttttgaa taaatggctt gacaagaaag ataaaaaaca gggagacttt
    73621 ccctttatta tagataatgc aattagattt tcaagcagtg gtgggatata taatgctaga
    73681 ctaaaagaag atgggaaaaa aataatttta aaagaggcta gaccgtatac aggtctagga
    73741 tttgatggta cttattcttc agagagatta gcttcggagt gcaaagcact aaaaattcta
    73801 aatgaatgga gtgagatgcc taaaatatac tggtacggta agatctggga gcacaccttc
    73861 ttaggaattg aacatatgaa gggcgttcca ctaaatagat gggttaccaa taattttcct
    73921 ttatatgaag ttgttgataa gaccaaagat tatctattga gagtttcaaa gatagtagaa
    73981 aaactcatcg atttaacgaa taagtttcat tctgaaaatg tatatcatca agatttacat
    74041 ttaggaaata tcttggttaa ggatgaagat gagattagta taatagactg ggaacaggct
    74101 gtcttttcga atgatgaaaa agttgtacat aaagttgcag cccctggttt tagagcatgg
    74161 cgagaaacac ttcccagtga gatagattgg tatggtatta gacaaatagc tcattattta
    74221 tacatgccac tagtaactac atcggatttg acatacaact atgtaagtca aaccaggata
    74281 gaaggaaaaa aactatttga gtctttgggt tatacaagag aacatataga ttatgtagaa
    74341 agtttattgt catatctaga ttctaaatgt ccacagattg agaatatttc caggaaaaaa
    74401 gttttaaaac ccatgcatga gattagaact atcgagagtg agcaagatat acaagatttt
    74461 attataaaag cttttctttt agtgaactga taggtatttt cttagcaaac gataaagttt
    74521 tagggccgat acaatcaatt gcctattcat taaataagat aaatacaacc aaagatttaa
    74581 ggaaaccgtt tttaaaatac ttaagtggag agaagaattt tatagacgct gaacatgata
    74641 ataacggact gtatacttca tcaatagatg tgatacacat gaaagatgtt gtatattcta
    74701 ttacaccaga aaataaatta agtattgact tctcatttaa gtcaccattt agggtattat
    74761 taacaggaac ttctggtagt gggaaaacaa cgattttaaa tttaattaat ggttctttaa
    74821 agccacaaaa aggttatgta aatttgttat cacatgggaa aaagagttca gattcaatac
    74881 caacagttga tcagacacca tatatttttg acactactat tcgtgagaac gtaactttat
    74941 ttcaaaatga atatttttca gatgatcaga taattgaggt gttaaaaaag gtaaatctat
    75001 atgaagaatt agaaaagata gatatactaa attatcaatg tggtgaaaat ggtagtaatt
    75061 tgtctggagg tcaaaaacaa aaaatagctt tagctagagc tctgattaga aataataaag
    75121 tgtacttatt tgacgaaata tcagctaatt tagataatga taattcaaat tccatacatg
    75181 atattctgtt caatttaggt atttcattta ttgaagtttc acatcattat gacttaaatg
    75241 acaagagata cactgatata taaattggaa aatggaacac ttttcaaaat taagtgattg
    75301 gaggcaagaa tatggataaa gattatatat taaaagtgaa agggctgtat catcaatttt
    75361 tactgggaaa caataaaacg ttgcaagtgc tgaaaaatgt ttctctttct gcttcgagag
    75421 gagaatttat aagtattcta ggaattagtg gttctggaaa gtcaacttta ttaaaatgta
    75481 tttctagttt gcttgaacca acaagtgggg aagtaatttt aaatggaatc aacccctata
    75541 aaatcagaaa tgcaaaattg tcaagtataa gacgtaacga agtatctttt atatttcaag
    75601 catacaattt aataccttcc ctgccggtaa tagaaaatat agcacttcct ttgcgattat
    75661 cacaaaaaaa attaactatt aaaaatgtag aaaacttact caaaagaatg aagtttaatg
    75721 ctggcttaaa cgattttgtt ggaactctgt ctggtggaga acaacagaag gttgctatag
    75781 ctagagcggt tattgctgat agtgatataa tatttgctga tgagccaact ggggctttag
    75841 acagcgtttc tcgtgaagta atttttgaat tattgagaga gttagtaggg gcgggtaagt
    75901 gtgtaattat ggtaacgcac gatatagaat tggcctcgaa aactgatcgt gcattaatat
    75961 tgaaagatgg aaaaattttc aaagaacttc atagacctag cggggaagag ttgtataaaa
    76021 tcttagaggt acaatcaact acggaggaat agagatgctc agattagttt actatcaatt
    76081 tttacataat aagaaacaat ggttaggcgt ttcaccagta atttttgttt cgagtttagt
    76141 tatgggattg gctgttaatg gggtaattaa tgttgagaat aattcgcaag tatttgtcgg
    76201 acttccagat cctaaaccaa tttttatgtt tccgatagta ttcggaggag taacattatt
    76261 ctttgtgctc tctaacataa taaatatgtt ggttgaaatt tttagagatg attacgaact
    76321 tctggaggtg ttgggagcaa gtctccttca actatcattt cttgtggggg gacagatttt
    76381 tatcatttcc tcgattatta gttttattgc atatctatgc tctatatttg ttacgtcaaa
    76441 ttattattat tttttacaat actttttcgg ggaaaatata ttacctgata tccaatttca
    76501 aacgagtgct gttggatgta tcattacagt agtgttgatt tcatttttag cctttctaag
    76561 tggttgcttt tatacgttca agaagattag aaataggaag agttctaaaa taaggcatgt
    76621 tctttcaata gtaaaaagaa tactgctatt ggctggtttt agtgttatct ggttgctttc
    76681 tttgcaacaa attttccaag atagcacaat tttagcgaag gcccagataa tattcaatat
    76741 tgtaatctta gatattgtga ttatttatca attatctcct tttatacagt catgttttat
    76801 caaactactt tctataatta tatttagaaa taattttatg ttcattgttt cgaagtggaa
    76861 tttactatat cgtaagcctt atataaaatc tatcagtgct gcaattacag gagctatatt
    76921 actaatttct agttttcaaa tgatttctca gaatatacta tctcaatttc aagatgacag
    76981 tgatttagag ctaaaagtgg catttattgt ctatgtagga gcaccaattt tgatagtact
    77041 tgcaaatatt atttcaattg catttttgtc atcgcatcaa gaaaggattg agattcagca
    77101 atttgaaatt ttaggaactt ctaattacca gatggttaag attaaagttg gtgaggctat
    77161 atttttgaca tttgttactt cattaattgc atttttactt aacattaaaa ttatggcttt
    77221 aatatactac tctttagggg atattttaat agatgatatg aatcttttgg ggttaatact
    77281 tccaaatttt atagtgtcta ttattttatt tattttaata tttattacta aaagttccta
    77341 ttttatcttt aagaatgcaa aaattatttc ttaaaaattt gtaagttttc gctatataaa
    77401 atagttaaat ctattttgta tcattgcttg cattttactg gtggagagaa tataatgagg
    77461 gtggataaag tacttaatcc caaaaattta aataggagga gctagctatg gcagaagaag
    77521 tattaaatct tcaattagta tctgttcaag ttgacgaaac agatgaagtt gatggaatgc
    77581 gatttagtac attcagtaca aaccgttgcg gtaactggag tgcttttagt tgggaaaatt
    77641 gttaattcat ttaaattgta aactttaggg attctctgaa gttatggatg tcgttccaat
    77701 atgtgcacgt tggaatgtta gtgcttatat ggggggaaca gaatcctctc ttgattgaag
    77761 acaagttagc cattaggctg gtttgtctct ttgtcaactg tagtgggttg atataatagt
    77821 attagtgagt gggataaaag tttcatttag tttattcagt acaaatttaa cgggtcaaga
    77881 tttattgaac tgcaccccaa tagttagaca gaaaaaatct aacttttggg gtgttttatt
    77941 atgaaattga gttatgaaga taaagttcag atctatgaac taagaaagca aggacaaagc
    78001 ttcaaacagc tttcaaaaag atttggtgtg gatgtttctg gtctaaagta catggtgaaa
    78061 ttaattgacc gttatggcat agaaatcgtt aaaaaaggga agaatcgtca ctattcttct
    78121 aaattgaaac aagaaatgat ggataaagcc ttactggaag gttgttcaca aagaagtatt
    78181 agtcttgatt atgccctccc aaaccaagga atgctttcat tttggccggc acaatacaag
    78241 aaaaacgggt atactattgt tgagaaaaca agagggagac cagctaaaat gggacgtaaa
    78301 cggaagaaga cttgggaaga aatgacagaa ctagaacgac tccaggagga gaatgaacgc
    78361 ttacggactg aggtggccta cctaaaaaag ttaaaagagt tagaggaaag ggacgaagcc
    78421 ctagagcgag aaaggcagag acagttagag aaatggtttc aggaggattt cgactagatt
    78481 ttcttcttga aacagcacgt ttagctcgct cgacttacta ttatcagttg aaacaactgg
    78541 atggggttga taaagataaa gagattaaaa ccgaaattca gggcattgat aatgaacata
    78601 aaggcaacta tggctatcgt cgaatccatt tagaactaag gaatcgtggt tttgtggtca
    78661 atcataagaa agttcaacgg ttgatgagaa ttcttggttt aacggctcga attcgccgta
    78721 aacggaagta ttcttcctac caaggagaga ttggcaagaa agcagagaat ctcattcaac
    78781 gccagttcga agcatcgagg ccaatggaaa agtgctatac agatgtgaca gagtttgcca
    78841 ttccaaatag cacacagaaa ctctatttat caccagtttt agatggtttt aacagtgaaa
    78901 tcattgctta tcatctttct acttcgccaa acttagaaca agtgaagagt atgttagaac
    78961 aggcctttac agagaaatac tatgagaata cgattctcca tagtgaccaa ggctggcaat
    79021 accaacacga ttcttatcat cggttcctag agagtaagga aattcaagca tccatgtcac
    79081 gcaagggcaa cagcccagac aacggcatga tggaatcttt ctttggcatt ttaaaatccg
    79141 aaatgtttta tggctatgag aagaacttta gatctttaga aaaccttgaa caagctattg
    79201 tggactacat tgattactac aacaacaaac gaattaaggt aaaactaaaa ggacttagtt
    79261 ctgtgcagta cagaactaaa tcctttggat aaattatttg tctaattttt tggggtcagt
    79321 acagtattaa ataccatgat cttatgcgtt ttataataaa aaatctgttc ttgttttatt
    79381 tttagaaaat ttactaaaga ctaaaaatat tatgaataat ttaaaaaata gtcaggttat
    79441 atagtttttt gaaattaaaa ttattttatc gttgaaatta gttaaaaatt tttataaaat
    79501 caagatgcaa ggctatgaga tgttctctag tttaattttt catacttcga gaatataaag
    79561 ttatataaaa atgcattagc atattttgtt attgagggaa gtataaaaat cattaaagtt
    79621 atccaaacta gtaattgatt ctgtaatata aagaagagta gaactgggat aatttcaata
    79681 attctaataa gaacggcaat aaaaaaatgt ttataggcta acatgattga attgtgtaga
    79741 gaatttttta aagtgttatt atatctaccg attaaaggaa ttagaaatgt tgttgctatt
    79801 aaatgaagta tgatatatat tactccaata tgtcgtaaga tagaaatgat atatataggt
    79861 aatggtatgt agggtaggaa gaacaaactg aataataaga ttaaaattgg taaattagat
    79921 attaatgctg ctcctaaatt tttccaataa tctttaaaaa aactgtttgc gaagtctcta
    79981 tagggatagg attcctcgtg tcgtacaatt tttattagag ttgctattag ggcactttca
    80041 cctgatccga tagcaataac tgttactact gacgctacat agagtagatt taacattata
    80101 agatttgaaa ctttatcaat aaattttatc tgcatcttta actcctgctg tttttatact
    80161 tataatatca catcatttga gtttcatcaa ctttgaatac attaagaaag aatataacta
    80221 tgaggaaagg aaaaaattat tatgaataaa tccaaaaaat ataaagaaag aattcattat
    80281 gaatacgata atcttactaa atcagagaaa aaattgctga ctatatttta gttagagata
    80341 gtgaaatagt ttatgaaacg tcttcagaaa ttgttagtaa agtaaaagtt ggagagggaa
    80401 ctcttaatcg attttgcaaa aagattggat actctggttt tcaggaacta aaattaaaaa
    80461 tgacgaaaga tatattagag ttagaatctc aaaaaatgag tagtgacaca tttattgatg
    80521 aaataaaaaa taattattta tctattgtgg aaagtacaag aaaattaatt gatggtagac
    80581 aaatagaatt agctataaaa ttaataagag aagcaaacca gattttaatg attggtgtgg
    80641 gttctagtgg aaatgcggct agagaatttg agagtagttt gttaagaatt ggaataataa
    80701 gtaagacggt aattgatacc cattttcaac tcatgcatac tgcgttattg aaagataatg
    80761 atttgataat agcgtttagt ttatctggtt ccacaaaaga agttgaggaa actttattaa
    80821 acgcaaaaag aaaaaatgtt aaaattattt caataacaaa ttattcgtcc agaaatatag
    80881 caaaattatc tgactgcgtt cttttgacat caaaaaaaga atcttattta gagggtggta
    80941 gtttaatggc taaggcttct caactattca taattgatgt aatatgcact agactctctt
    81001 taataaatta tgaagatact atatgtaaaa aagaagagat tgcttctttg ctgtcaaata
    81061 aagtggaata aatcaataat ttttaaattt taataaaaat tttttaaaat aaattaaaaa
    81121 acgatcctaa aagggtcgtt tttttgctaa agttttaaaa ataaacaata attaagatta
    81181 tagtgcgttg aatctatatt aggacataac aattcttaaa tcattgttag aaattagttt
    81241 gaatttccca atcaatttgt tcgattttta catcattgca ttatatcatg tgactattaa
    81301 ccttgttttc tcctaaaatt gattttcttc ttttcttatc ttgtccactc gaaacaagta
    81361 ttgtaagaat ttgattattt ttgaaagtac ttttaatata tttgagatag ttaaaaaaga
    81421 tttgaaacta aattccaaat tagaaaaaga cttgaaatgc taaaaaaaaa aagtatactc
    81481 taattgaaaa cggtaacaaa actaatttag agaatgaaat atagagtatt tctctcttaa
    81541 aagtttttgg tgaaacgaga tgtagaaagg agatttagcc aaagagtcta ttagtgctag
    81601 aataatagat tagaattatt ttagaaaaac gaagtgagca gcttataaat tcaagtcccc
    81661 aaatagattc atactagtat cttttgcaaa aaataaaggg cgacttcctt catgaatatc
    81721 aatttcatct ataaggaagg tagctaattg aactaactta tttattctgt ttgtcgctag
    81781 aaaaatcaga cctccttgtg aagattgagg agatacttaa tgaaaatcaa agaagaaact
    81841 agcaagctag tagcagattg cccaaaacac cgctttgagg ttgtagataa gactgacgta
    81901 tataatccaa ggtgaagcga ctgtggtttg aagagatttt caaagagtat aggctagaga
    81961 gtagtgtttt tatgtccttc tagtagaaaa tgctagacag aagaatgggg aacttggata
    82021 ggaaaaatag attgagaaag gaggttagaa gagatgatta ttacaaaaat tagccgttta
    82081 ggaacttatg tgggagtaaa tccacatttt gcaacattaa tagattttct agaaaaaaca
    82141 ggactagaaa atttaacaga aggttcgatt gttatcgatg gtaatcgatt gtttgggaat
    82201 tgatttactt atctagcaga tggtcaagca ggggctttct ttgaaacaca ccaaaaatat
    82261 ttggatattc atttagtttt ggaaaacgaa gaagccatgg ctgttacatc gccggaaaat
    82321 gtaagcgtta cccaagaata tgatgaagag aaagatattg aattatacac agggaaagtg
    82381 gaacagttgg ttcatttgag agctggcgaa tgcctcatca cttttccaga agatttacat
    82441 caacccaagg ttcgtataaa tgatgaacct gtgaaaaaag ttgtctttaa agttgcgatt
    82501 tcttaatgta gaaagagaag aacgatgaaa aaaatgagaa agtttttatg tctagctgga
    82561 attgcgctag cggctgttgc cttggtagct tgttcaggaa aaaaagaagc tacaactagt
    82621 actgaaccac caacagaatt atctggtgag attacaatgt ggcactcctt tactcaagga
    82681 ccccgtttag aaagtattca aaaatcagca gatgctttca tgcaaaagca tccaaaaacg
    82741 aaaatcaaga ttgaaacatt ttcttggaat gacttctata ctaaatggac tacaggttta
    82801 gcaaatggaa atgtgccaga tatcagtaca gctcttccta accaagtaat ggaaatggtc
    82861 aactcagatg ctttggttcc gctaaatgat tctatcaagc gtattggaca agataaattt
    82921 aacgaaactg ccttaaatga agcaaaaatc ggagatgatt actactctgt tcctctttat
    82981 tcacatgcac aagtcatgtg ggttagaaca gatttgttaa aagaacataa tattgaggtt
    83041 cctaaaactt gggatcaact ctatgaagct tctaaaaaat tgaaagaagc tggagtttat
    83101 ggcttgtctg ttccgtttgg aacaaatgac ttaatggcaa cacgtttctt gaacttctac
    83161 gtacgtagtg gtggaggaag cctcttaaca aaagatctta aagcagactt gacaagccaa
    83221 cttgctcaag atggtattaa atactgggtt aaattgtata aagaaatctc acctcaagat
    83281 tctttgaact ttaatgtcct tcaacaagct accttgttct atcaaggaaa aacagcattt
    83341 gactttaact ctggcttcca tatcggagga attaatgcca acagtcctca attgattgat
    83401 tcgattgatg cttatcctat tccaaaaatc aaagagtctg ataaagacca aggaattgaa
    83461 acctcaaaca ttccaatggt tgtttggaaa aattcaaaac atccagaagt tgctaaagca
    83521 ttcttagaag cactttataa tgaagaagac tacgttaaat tccttgattc aactccagta
    83581 ggtatgttgc caactattaa ggggattagc gattctgcag cctataaaga aaatgaaact
    83641 cgtaagaagt ttaaacatgc tgaagaagta attactgaag ctgttaaaaa aggtactgct
    83701 attggttatg aaaatggacc aagtgtacaa gctggtatgt tgactaacca acacattatt
    83761 gaacaaatgt tccaagatat cattacaaat ggaacagatc ctatgaaagc agcaaaagaa
    83821 gcagaaaaac aattaaacga tttatttgag gctgttcagt agatgtaaaa gactagaaaa
    83881 taggtgggct agtgagctga aaagctctag cccaatcttg taaaagaagg gagaaggaga
    83941 atggttaaag aacgtaattt aactcgctgg atatttgttt tgccagctat gattatcgta
    84001 ggattactct ttgtttatcc gtttttctcg agtatttttt atagctttac caataagcat
    84061 ttgattatgc ctaattataa atttgttggt ttggctaact ataaagctgt gctatcagat
    84121 cccaacttct ttaatgcgtt ctttaattca attaagtgga ccgttttctc attagttggt
    84181 caagttttag tagggtttgt attggcttta gctcttcaca gagtacgcca cttcaagaaa
    84241 ttatatagga ccttattgat tgttccttgg gcatttccta ccatcgttat tgccttttct
    84301 tggcagtgga ttctaaacgg ggtttatggc tacttaccta atctaatcgt aaaattaggt
    84361 ttaatggaac atacacctgc atttttgaca gatagtacat gggcattcct atgtttggtg
    84421 tttatcaaca tttggtttgg agcaccaatg attatggtta atgtgctttc agctttgcaa
    84481 acagtaccag aagaacaatt tgaggctgct aagatagatg gtgcttcaag ttggcaggtg
    84541 ttcaagttta tcgtctttcc acatattaaa gtggttgtag gacttctagt tgttttgaga
    84601 actgtatgga tctttaataa ctttgacatt atctacctca ttactggtgg tggaccagcc
    84661 aatgctacaa cgacgcttcc aatttttgct tacaacctgg gttggggaac taaattgttg
    84721 ggtcgtgctt cagcagttac agtattgctc tttatcttct tggtggcgat ttgctttatc
    84781 tactttgcta tcatcagtaa gtgggaaaag gagggtagaa aataatgaag aagaaatcca
    84841 gtatttattt agatattctc tcacatgtac ttttagttgg tgcgaccatc gttgcaattt
    84901 tcccattggt atggattatc atatcttctg tcaaagggaa aggggaatta actcagtatc
    84961 caacacgatt ttggcctgaa cagtttacat tagattattt cactcatgtt atcaacgatt
    85021 tgcacttcat tgataacatt cgaaacagtt taatcattgc cttggctaca accctcatta
    85081 cgattattat ttctgctatg gcagcctatg gtattgttcg attctttcct aaattgggag
    85141 caatcatgtc gagactactc gtcattacct atattttccc accaattttg ttagcaattc
    85201 cctattcaat tgccattgct aaagttgggt taacaaatag tttatttggc ttgatgatgg
    85261 tttatctatc ttttagtgtt ccatatgcag tttggctctt agttggattt ttccaaacag
    85321 ttccaattgg aattgaagaa gcggctagaa ttgatggtgc aaataaattt gttacgtttt
    85381 ataaagttgt gctaccgatt gtagcaccag gtattgtagc aacagctatt tatacattta
    85441 tcaatgcttg gaatgaattc ctgtatgcct tgattttgat taacaataca ggaaagatga
    85501 cagtagcagt agcccttcgt tcacttaatg gttcagaaat actagactgg ggagatatga
    85561 tggcagcgtc tgttattgta gttcttccat caattatttt cttctctatc atccaaaata
    85621 agattgcaag tggattatca gaaggatctg tgaagtagac gaaagaagga aaaaaaatga
    85681 ataaaagagg tctttattca aaactaggaa tttctgttgt aggcattagt cttttaatgg
    85741 gagttcctac tttgattcat gcgaatgaat taaactatgg tcaactgtcc atatctccta
    85801 tttttcaagg aggttcatat caactgaaca ataagagtat agatatcagc tctttgttat
    85861 tagataaatt gtctggagag agtcagacag tagtaatgaa atttaaagca gatgaaccaa
    85921 actctcttca agctttgttt ggcctatcta atagtaaagc aggctttaaa aataattact
    85981 tttcaatttt catgagagat tctggtgaga taggtgtaga aataagagac gcccaaaagg
    86041 gaataaatta tttattttct agaccagctt cattatgggg aaagcataaa ggacaggcag
    86101 ttgaaaatac actagtattt gtatctgatt ctaaagataa aacatacaca atgtatgtta
    86161 atggaataga agtgttctct gaaacagttg atacattttt gccaatttca aatataaatg
    86221 gtatagataa ggcaacacta ggagctgtta atcgtgaagg taaggaacat tacctcgcaa
    86281 aaggaagtat tgatgaaatc agtctattta acaaagcaat tagtgatcag gaagtttcaa
    86341 atattccctt gtcaaatcca tttcagttaa ttttccaatc aggagattct actcaagcta
    86401 actattttag aataccgaca ctatatacat taagtagtgg aagagttcta tcaagtattg
    86461 atgcacgtta tggtgggact catgattcta aaagtaagat taatattgcc acttcttata
    86521 gtgatgataa tgggaaaacg tggagtgagc caatttttgc tatgaagttt aatgactatg
    86581 aggagcagtt agtttactgg ccacgagata ataaattaaa gaatagtcaa attagtggaa
    86641 gtgcttcatt catagattca tccattgttg aagataaaaa atctgggaaa acgatattac
    86701 tagctgatgt tatgcctgcg ggtattggaa ataataatgc aaataaagcc gactcaggtt
    86761 ttaaagaaat aaatggtcat tattatttaa aactaaagaa gaatggagat aacgatttcc
    86821 gttatacagt tagagaaaat ggtgtcgttt atgatgaaac aactaataaa cctacaaatt
    86881 atactataaa tgataagtat gaagttttgg agggaggaaa gtctttaaca gtcgaacaat
    86941 attcggttga ttttgatagt ggctctttaa gagaaaaaca taatggaaaa caggtcccta
    87001 tgaatgtttt ctacaaagat tcgttattta aagtgactcc tactaattat atagcaatga
    87061 caactagtca gaatagagga gagagttggg aacaatttaa gttgttgcct ccgttcttag
    87121 gagaaaaaca taatggaact tacttatgtc ccggacaagg tttagcatta aaatcaagta
    87181 acagattgat ttttgcaaca tatactagtg gagaactaac ctatctcatt tctgatgata
    87241 gtggtcaaac atggaagaaa tcctcagctt caattccgtt taaaaatgca acagcagaag
    87301 cacaaatggt tgaactgaga gatggtgtga ttagaacatt ctttagaacc actacaggta
    87361 agatagctta tatgactagt agagattctg gagaaacatg gtcgaaagtt tcgtatattg
    87421 atggaatcca acaaacttca tatggcacac aagtatctgc aattaaatac tctcaattaa
    87481 ttgatggaaa agaagcagtc attttgagta caccaaattc tagaagtggc cgtaagggag
    87541 gtcaattagt tgttggttta gtcaataaag aagatgatag tattgattgg aaataccact
    87601 atgatattga tttgccttcg tatggttatg cctattctgc gattacagaa ttgccaaatc
    87661 atcacatagg tgtgctgttt gaaaaatatg attcgtggtc gagaaatgaa ttgcatttaa
    87721 gcaatgtagt tcagtatata gatttggaaa ttaatgattt aacaaaataa aggagaaaaa
    87781 acatggttaa atacggtgtt gttggagcag ggtattttgg agctgaattg gctcgctaca
    87841 tgcaaaagaa tgatggagca gagattactc ttctctatga tccagataat gcagaggcga
    87901 ttgcagaaga attgggagca aaagtagcaa gttccttaga tgagttggtt tctagcgatg
    87961 aagtagattg tgttatcgtc gcaactccaa ataatcttca taaggaaccg gttattaagg
    88021 ctgcacagca tggtaaaaat gttttctgtg aaaaaccaat tgcgctttct tatcaagatt
    88081 gtcgcgagat ggtagatgcg tgtaaagaaa acaatgtaac ctttatggca ggacatatta
    88141 tgaatttctt taatggtgtt catcatgcaa aagaactcat taatcaagga gttatcggag
    88201 acgttctata ttgtcataca gctcgtaatg gttgggaaga acaacaaccg tcagtatcat
    88261 ggaaaaaaat tcgtgaaaaa tcaggtggtc acttgtatca ccacatccat gaattggatt
    88321 gcgttcaatt ccttatgggg ggcatgcctg aaactgtaac catgacaggt ggaaatgtgg
    88381 cccatgaagg tgaacatttc ggtgatgaag atgatatgat ttttgtcaat atggaatttt
    88441 ctaataagcg ttttgccttg ttagaatggg gttcagctta tcgttggggt gaacattatg
    88501 tcttaatcca aggaagcaaa ggtgccatcc gcttagactt attcaactgt aaaggaactc
    88561 ttaagctaga tgggcaagaa agctatttct tgattcacga atcgcaagaa gaagatgatg
    88621 atcggactcg tatctatcat agtacagaga tggatggagc aattgcttat ggtaaaccag
    88681 gtaaacgtac tccattatgg ctatcatctg tcattgataa agaaatgcgc tatctgcatg
    88741 agattatgga aggagcccca gtatcagaag aatttgcaaa acttttgaca ggtgaagctg
    88801 ccctagaagc aattgctact gcagatgctt gtacccagtc tatgtttgaa gatcgcaaag
    88861 taaaattgtc agaaattgta aaataaattt tggtattctc ctatttatag gtcgacttgc
    88921 tcctctgaaa gtacttttag aggagctgtt tgactttgct agtttttgaa actgaaatct
    88981 attatactac aaactattga aagcgtttta attttaaggt ataataatct catagaaata
    89041 aagaaaagga ggaaagagga tgccacagat tagcaaagaa gccttgattg agcaaatcaa
    89101 agatggaatc atcgtttctt gtcaggctct tcctcatgaa ccgctttata cagaagcggg
    89161 aggggtgatt cccttgctgg tcaaagcggc tgagcaaggt ggagcagtcg gtatccgagc
    89221 aaacagtgtt cgcgatatca aggaaattaa ggaagtcact aaacttccaa tcattgggat
    89281 tatcaaacgt gattatccac ctcaggaacc cttcatcacg gctactatga aagaagttga
    89341 tgaattggca gaactggaca tcgaggtgat tgctctggat tgtaccaagc gtgaacgcta
    89401 cgatggtttg gaaattcaag agttcattcg tcaggttaag gagaaatatc ctaatcagct
    89461 tttgatggct gatactagta tcttcgaaga agggctagca gctgtagaag caggaattga
    89521 ctttgtcgga acaaccttat caggctacac atcctacagt ccaaaagtag acggtccaga
    89581 ttttgaattg attaagaaac tctgtgatgc cggtgtagat gtcattgcag aaggaaaaat
    89641 tcatacacca gaacaagcca aacaaatcct tgaatatgga gtgcgaggca tcgttgttgg
    89701 tggcgccatt actagaccaa aagagattac agaacgcttc gttgctagtc ttaaataaga
    89761 tgtgagaggg agttttatgt ttaaagtttt acaaaaagtt ggaaaagctt ttatgttacc
    89821 tatagctata cttcctgcag caggtctact tttggggatt ggtggtgcac tttcaaaccc
    89881 aaccacgata gcaacttatc caatactaga caatagtatt tttcaatcaa tattccaagt
    89941 aatgagctct gcaggagagg ttgtattcag taatttgtca ctacttctct gtgtgggatt
    90001 atgtattggc ttagcgaaac gagataaagg aaccgctgcg ttagcaggag taactggtta
    90061 cttagttatg actgcaacga tcaaagcttt ggtaaaactt tttatggcag aaggatctgc
    90121 aattgatact ggagttattg gagcattagt tgtcggaata gttgccgtat atttgcacaa
    90181 ccgatataac aatattcaat taccttccgc tttaggattc tttggaggtt cacgcttcgt
    90241 tcctattgtt acatcgttct cttctatctt gattggcttt gtcttctttg ttatttggcc
    90301 acctttccaa caacttcttg tttctacagg tggatatatt tctcaggcgg gtccaattgg
    90361 aacttttcta tatggatttt taatgagact ttctggagca gtaggcttac atcatataat
    90421 ttaccctatg ttttggtata ctgaacttgg tggtgttgaa actgttgcag gacaaacagt
    90481 ggttggagct caaaaaatat tttttgctca attagccgat ccggcccatt ctggattatt
    90541 tacagaagga acaaggtttt ttgcaggtcg tttctcaaca atgatgttcg gtttaccggc
    90601 tgcctgttta gcgatgtacc atagtgttcc taaaaatcgt cgtaaaaaat acgcgggttt
    90661 gttttttgga gttgctttaa catcttttat taccggtatt acagaaccaa ttgaatttat
    90721 gtttctattc gtcagtccgg ttctatatgt tgttcacgca ttccttgatg gtgttagctt
    90781 ctttattgca gacgtcttaa atatttcaat aggaaacaca ttttcaggag gtgtaatcga
    90841 tttcacttta tttggaattt tgcaggggaa cgctaagacg aattgggttc ttcagattcc
    90901 aattggactt atttggagtg ttttgtatta tattattttt agatggttca ttactcaatt
    90961 caacgttcta acgccaggac gaggagaaga agtagattct aaagaaattt ctgaatccgc
    91021 agattcaact tcaaatactg cagattattt aaaacaggat agcctacaaa ttatcagagc
    91081 cttgggtgga tcaaataata tagaagatgt agatgcttgt gtgacacgtt tacgtgtagc
    91141 tgtaaaagaa gttaatcaag ttgataaagc acttttaaaa caaattggtg cagttgatgt
    91201 cttagaagtg aagggtggca ttcaagcaat ctatggagca aaagcaatct tatataaaaa
    91261 tagtattaat gaaattttag gtgtagatga ttaagtactt actgacttaa taaaaaacag
    91321 aggagagtga tggatgagta ggatgaaatg aaatcgtata caagaaataa agaactcatt
    91381 atccaagttg gatacgctta ttacatagga gaatacaaat gaaatttaga aaattagctt
    91441 gtacagtact tgcgggtgct gtggttcttg gtcttgctgc ttgtggcaat tctggcggaa
    91501 gtaaagatgc tgccaaatca ggtggtgacg gtgccaaaac agaaatcact tggtgggcat
    91561 tcccagtatt tacccaagaa aaaactggtg acggtgttgg aacttatgaa aaatcaatca
    91621 tcgaagcgtt tgaaaaagca aacccagata taaaagtgaa attggaaacc atcgacttca
    91681 agtcaggtcc tgaaaaaatc acaacagcca tcgaagcagg aacagctcca gacgtactct
    91741 ttgatgcacc aggacgtatc atccaatacg gtaaaaacgg taaattggct gagttgaacg
    91801 acctcttcac agatgaattt gttaaagatg tcaacaatga aaacatcgta caagcaagta
    91861 aagctggaga caaggcttat atgtatccga ttagttctgc cccattctac atggcaatga
    91921 acaagaaaat gttagaagat gctggagtag caaaccttgt aaaagaaggt tggacaactg
    91981 atgattttga aaaagtattg aaagcactta aagacaaggg ttacacacca ggttcattgt
    92041 tcagttctgg tcaaggggga gaccaaggaa cacgtgcctt tatctctaac ctttatagcg
    92101 gttctgtaac agatgaaaaa gttagcaaat atacaactga tgatcctaaa ttcgtcaaag
    92161 gtcttgaaaa agcaactagc tggattaaag acaatttgat caataatggt tcacaatttg
    92221 acggtggggc agatatccaa aactttgcca acggtcaaac atcttacaca atcctttggg
    92281 caccagctca aaatggtatc caagctaaac ttttagaagc aagtaaggta gaagtggtag
    92341 aagtaccatt cccatcagac gaaggtaagc cagctcttga ataccttgta aacgggtttg
    92401 cagtattcaa caataaagac gacaagaaag tcgctgcatc taagaaattc atccagttta
    92461 tcgcagatga caaggagtgg ggacctaaag acgtagttcg tacaggtgct ttcccagtcc
    92521 gtacttcatt tggaaaactt tatgaagaca aacgcatgga aacaatcagc ggctggactc
    92581 aatactactc accatactac aacactattg atggatttgc tgaaatgaga acactttggt
    92641 tcccaatgtt gcaatctgta tcaaatggtg acgaaaaacc agcagatgct ttgaaagcct
    92701 tcactgaaaa agcgaacgaa acaatcaaaa aagctatgaa acaatagtcc ttagttattc
    92761 tataaaaagt agttttttaa agaacctaag agtgtatacc cccttttccc tctacacaga
    92821 tagtgtaaga aaagggggct tttgtttaaa atgtaagaaa ctgtcacgaa attaaaatga
    92881 agttcttaca taagcgaatc ataaaaaatt tcattttgat tttaaaacag ttcaagaaag
    92941 tcaaaaaatt attctatttg aaagagaggt gccgactgtg aaagtcaata aaatccgtat
    93001 gcgggaaaca gtgatttcct acgctttcct agcaccagta ttattcttct ttgtcatctt
    93061 tgtgttggct ccgatggtga tgggcttcat tacaagtttc tttaactact caatgactaa
    93121 atttgagttt gtaggcttgg ataactatat ccgtatgttt aaagatcctg tctttacaaa
    93181 atctctgatt aacacagtta ttttggttat tggatctgta ccagttgttg ttctattctc
    93241 actctttgta gcatctcaga cctatcatca aaatgtcatt gccagatcct tctaccgttt
    93301 cgtcttcttc cttcctgttg taacgggtag tgttgccgtg acagttgttt ggaaatggat
    93361 ttatgaccca ctatcaggga ttctaaactt tgtccttaag tcaagccaca tcatcagcca
    93421 aaacatttct tggttgggag ataaaaactg ggcattgatg gcgattatga ttattctctt
    93481 gaccacttca gttggtcagc ccatcatcct ttatatcgct gccatgggga atattgacaa
    93541 ttcactggtt gaagcggcgc gtgttgatgg tgcaactgag tttcaagttt tttggaagat
    93601 taaatggcca agccttcttc caacaactct ttatattgca atcatcacaa caattaactc
    93661 attccagtgt ttcgccttga ttcagctttt gacatctggt ggtccaaact actcaacaag
    93721 taccttgatg tactaccttt acgaaaaagc cttccaattg acagaatacg gctatgccaa
    93781 cacaattggt gtcttcttgg cagtcatgat tgctatcgta agctttgttc aatttaaagt
    93841 acttggaaac gacgtagaat actaaagaaa ggagacagct atgcaatcta cagaaaaaaa
    93901 accattaaca gcctttactg ttatttcaac aatcattttg ctcttgttga ctgtgctgtt
    93961 catctttcca ttctactgga ttttgacagg ggcattcaaa tcacaacctg atacaattgt
    94021 tattcctcct cagtggttcc ctaaaatgcc aaccatggaa aacttccaac aactcatggt
    94081 gcagaaccct gccttgcaat ggatgtggaa ctcagtattt atctcattgg taaccatgtt
    94141 cttagtctgt gcaacctcat ctctagcagg ttatgtattg gctaaaaaac gtttctatgg
    94201 tcaacgcatt ctatttgcta tctttatcgc tgctatggca cttccaaaac aagttgtcct
    94261 tgtaccattg gtacgtatcg tcaacttcat gggaatccac gatactctct gggcagttat
    94321 cttgcctttg attggatggc cattcggtgt cttcctcatg aaacagttca gtgaaaatat
    94381 ccctacagag ttgcttgaat cagctaaaat cgacggttgt ggtgagattc gtaccttctg
    94441 gagtgtagcc ttcccgattg tgaaaccagg gtttgcagcc cttgcaatct ttaccttcat
    94501 caatacttgg aatgactact tcatgcaatt ggtaatgttg acttcacgta acaatttgac
    94561 catctcactt ggggttgcga ccatgcaggc tgaaatggca accaactatg gtttgattat
    94621 ggcaggagct gcccttgctg ctgttccaat cgtcacagtc ttcctagtct tccaaaaatc
    94681 cttcacacag ggtattacta tgggagcggt caaaggataa tactctgcga aaatcgaatg
    94741 caaactacgt cagcttcacc ttgccatact taagtattgc ctgtggttag cttcctagtt
    94801 tgttcttcaa ttttcattga gtataggaaa atcaatctat caagatacag aagtatattt
    94861 tatagattta gagaatatag aagttataag tgtctacaaa atggagggta tgcagttact
    94921 ttatgaagtt ttgtcagaca cttatcaact taagaatggt tttagttaac tatcagaaac
    94981 gaaggaaaga gtatgatttt tgacgatttg aaaaacatca ccttttacaa agggattcat
    95041 cccaatttag acaaggctat cgactacctc taccaacatc gtaaagattc attcgaatta
    95101 ggaaagtatg agattgatgg agataaagtc tttctagttg ttcaggaaaa tgtcctcaat
    95161 caagttgaga ataatcaatt tgaacaccat aagaactatg cagatttgca tttgctgata
    95221 gaagggcatg aatattcgag ctacggttca cgtatcaaag acgaggcagt agcattcgac
    95281 gaagcgagtg acattggctt tgttcattgt tatgaacact acccactctt attgggttat
    95341 cacaattttg cgattttctt cccaggtgag ccacatcagc caaatggtta tgcaggcatg
    95401 gaagaaaagg ttcgaaaata tctctttaaa atcttgattg attaaaaata ggatgaattg
    95461 tttttttgta aagctttgat aatactctac catgaaattg atctttgtga ggtagagaaa
    95521 tgagaataaa atatttaaaa attggtatct tctaagtatg ctgcaagagc tagtttcttg
    95581 gatggacagg gaattacagt tgatgagatg gcttggataa ttaggggcat tgtgaatgca
    95641 ttgattggta gatacataaa attaggtgct tatgcggcta agtatggtat tagtatggca
    95701 cgctcgatct taagtagggc agctgcaact gcagcagcaa gagtaggatt atcgaccaag
    95761 atttctggat ggattttacg agtagctgtg aatgtagctg atgtatatgg taattttgcc
    95821 tacaatattg ctgcagcttg ggatgcacat gataaaatcc ctaacaatgg tcgtataaac
    95881 ttttaaaatg cgagaatgaa agcactttgt atttttttat tgaatatgtt agcttggaca
    95941 gtgcttgcaa tgataattcg tggagggcta gatggattta atgagcatac ttggagtact
    96001 attttaattg cttcgctgtt cggggtatat gattataagc ccatagataa aaatagaaaa
    96061 aagtccaaaa gaaaaaagaa aaaatagatt tgttcatggt agggacttat gaaagcttta
    96121 ctgacaaaaa agaaaacagt ttacaaagaa aaatgatgga ggagcaaaca tggcacaaaa
    96181 aggagtaagc cttatcaagg cagcatttga tacagacaac tttctcatgc gttttagtga
    96241 gaaagtcttg gacatcgtga cagccaatct tctttttgtc gtctcttgtt tgcccatcgt
    96301 gacgattgga gtggctaaaa tcagcctcta cgagaccatg ttcgaagtta agaagagcag
    96361 acgggtgcct gtttttaaaa tctatctaag atctttcaag caaaatctga aactaggtct
    96421 tcagctgggt ttaatggagt taggaattgt gtttcttacc ctttcagatc tctatctttt
    96481 ctggggtcaa acagctctgc ccttccaatt gctgaaagcc atttgtttag gtattctgat
    96541 ttttcttact atcgtgatgc tggctagtta ccctatcgcg gcacgttatg acctatcttg
    96601 gaaagaaatt cttcaaaaag gattgatgtt ggctagtttt aactttcctt ggttcttcct
    96661 catgttagcc attcttgtcc tcattgtgat ggttctttat ctgtccgcct tcagtctact
    96721 cttaggtggc tcagtcttcc tactttttgg gtttggacta ttggtcttta tccagactgg
    96781 attgatggag aaaattttcg caaaatacca ataggagctt tatttctgaa actactttca
    96841 aaggctccaa acgctattct ataagcgaga aactaaaatc taagtgtcta taagatattg
    96901 aaagcctttt cgggaaagtg tatactaaag aagtaaagaa aaatctgctt tagcagaaaa
    96961 taaaaataat aggagaaaat ctatgtcaga tttgaaaaaa tacgaaggtg tcattccagc
    97021 cttctacgca tgttatgatg atcaaggaga agtaagccca gaacgtacgc gtgccttggt
    97081 tcaatacttc attgataaag gtgttcaagg tctttatgtc aatggttctt ctggtgaatg
    97141 tatctaccaa agcgttgaag atcgcaagtt gattttggaa gaagtcatgg cggtagccaa
    97201 aggtaaattg accatcattg ctcatgttgc ctgcaacaat actaaagaca gtatggaact
    97261 tgctcgccat gctgaaagct tgggagtaga tgctattgca acgattccac caatttactt
    97321 ccgcttgcca gaatactcag ttgccaaata ctggaacgat atcagttctg cagctccaaa
    97381 cacagactac gtgatttaca acattcctca attggcaggg gttgctttga ctccaagcct
    97441 ttacacagaa atgttgaaaa atcctcgtgt tatcggtgtt aagaactctt ctatgccagt
    97501 tcaagatatc caaacctttg tcagccttgg tggggaagac catatcgtct ttaacggtcc
    97561 agatgaacag ttcctaggtg gccgcctcat gggtgctaag gctggtatcg gtggtactta
    97621 tggtgctatg ccagaactct tcttgaaact caatcagttg attgcggata aggacctaga
    97681 aacagcgcgt gaattgcagt atgctatcaa cgcaatcatt ggtaaactca cttctgctca
    97741 tggaaatatg tacggtgtca ttaaagaagt tttgaaaatc aatgaaggct tgaatattgg
    97801 atctgttcgt tcaccattga caccagtgac tgaagaagat cgtccagttg tagaagcggc
    97861 tgctgccttg attcgtgaaa ccaaggagcg cttcctctaa tctaaaagga ggtatttatg
    97921 acatactacg ttgcaattga tatcggtgga accaacatca agtatggttt ggttgatcaa
    97981 gaggggcaac ttcttgaatc gcatgaaatg ccaactgagg cgcataaggg tggacctcat
    98041 atcttacaaa agaccaaaga tatcgtagct agttatttag aaaaaggcct agtagcaggt
    98101 gttgccatat cttctgctgg gatggtggat ccggataagg gtgagatttt ctatgctggg
    98161 ccgcaaatcc ctaactacgc aggcacccag ttcaaaaagg aaatcgaaga aagctttact
    98221 attccttgtg agattgaaaa tgatgtcaac tgtgcaggtc ttgctgaggc agtatctggt
    98281 tcaggcaagg gagcaagtat gacactttgc ttgaccattg gaacaggtat cggtggttgc
    98341 ttgattatgg ataggaaagt cttccatggt tttagcaatt cagcctgtga agtcgggtat
    98401 atgcatatgc aggatggagc ttttcaagac ttggcttcta caacagcttt agtgaaatat
    98461 gtagctgaag cccatggaga agatgttgat cagtggaatg gccgtagaat tttcaaagaa
    98521 gccactgaag gaaacaaaat ctgcatggaa ggtattgacc gtatggttga ctatctagga
    98581 aaaggtctgg caaatatttg ctacgttgcc aatccagaag tggttattct tggtggtggt
    98641 atcatggggc aagaggctat cctcaaacct aagattcgca cagccttgaa agaggctttg
    98701 gtaccaagtt tagcagaaaa aacacgatta gaatttgccc atcaccaaaa tacagcaggg
    98761 atgttgggtg catattatca ttttaagaca aaacaatcct agtttggctc agccaaacta
    98821 ggattttctt acacgttttt gtctacgata gccgttgagt tttttatttt cccagtagct
    98881 attaaagatt ttttccttgc tttcgcgatt gatttccaaa aagtaggcat aaatcaaatc
    98941 gataaagaag agcataggaa gttgagcgga tattcgttgg atataggagg gttggctgtg
    99001 ggtggctaca agaacagtct ctgtataggt ctggctattt ttattgggaa cacttgtaaa
    99061 gagtacagtc tttgccccca tctccttggc atctaataga ctatctaaaa tagaaggagt
    99121 tgagcctgaa agtgagaagc ccagtactag acaattttca tccatgatgc tggttgtcca
    99181 ggcaaagccg tcttggtctg tcaaagcttc gcagaccacg cctagtcgca taaaacgtaa
    99241 tttcatttca cgggcgacga gaccagaact ccctgttcca aagaagtaga tacgctcagc
    99301 atcttcgatt agctgggcaa ttcgttctag ttggatttcg tcaatcaagt cttgtgtttg
    99361 ttccctcata ttgctataac ttctgaggac tcgtttggtc agtggactgt gcttggagac
    99421 ttggttggct tgattttctg cctgatgttg gtattggaaa ataaattctc ggtagccagt
    99481 aaagccacac tttttagcaa agcgggtcaa agcagcttga gaaatatgta atttttgggt
    99541 gacttgttga gaagataaat catctgtaat cgtttcagct tgcaaaaaat agcgagcgat
    99601 ttcttgctct aggtctgtca tttcttcaaa atgtgaatca atgatagttg cgatatctgg
    99661 tttgtccata gggaaagctc ctttacatga gtcatactgg aagactagat cagggaatag
    99721 tcacacttca ttataacaca taatataagg atagataaat aaaaacgcat ttctgtttta
    99781 aaaacgaaaa aatcgaaaaa gcttctctct tttccataat tttctactca aattgtggta
    99841 caattaagag taagatttta agttagaaat gagactgatt tgtatgagaa aatttaacag
    99901 ccattcgatt ccgattcggc ttaatttatt gttttcaatc gtcattttac tctttatgac
    99961 cattattggt cgtttgttgt atatgcaggt tttgaacaag gatttttacg aaaaaaagct
   100021 agcctcagct agtcagacca agattacaag cagttcagcc cgtggggaaa tttatgatgc
   100081 tagtggaaaa cctttggtag aaaatacgtt aaagcaggtt gtttccttta cgcgtagcaa
   100141 taaaatgacg gctacagact taaaagaaac agctaaaaag ttactgactt atgtgagcat
   100201 cagttctcca aatttgacag aacgccagct ggcggattac tatttggctg atcctgaaat
   100261 ctataaaaaa acagtggaag ctctcccaag cgagaaacgc ttggattcag atggaaatcg
   100321 tctatccgaa tcagaactgt ataacaatgc ggtcgatagt gtccaaacaa gtcaactaaa
   100381 ctatacagag gatgaaaaga aagaaatcta tctttttagt cagttaaatg ctgttggaaa
   100441 ctttgcgaca ggaaccattg ctacagatcc tctaaatgat tctcaggtgg ctgttattgc
   100501 ctctatttca aaggagatgc ctggcattag tatttctact tcttgggata gaaaggtttt
   100561 ggaaacttcc ctttcttcta tagttgggag tgtatccagt gaaaaagctg gtctcccagc
   100621 ggaagaagca gaagcctatc ttaaaaaagg ctattctcta aatgaccgtg taggaacctc
   100681 ctatttggaa aagcaatatg aagagacctt acaaggaaaa cgatcggtaa aagaaatcca
   100741 tctggataaa tatggcaata tggaaagcgt ggatacaatt gaggaaggta gtaagggaaa
   100801 caatatcaaa ctgaccattg atttggcctt ccaagatagc gtggatgctt tgctgaaaag
   100861 ttatttcaat tctgagctag aaaatggtgg agccaagtat tctgaaggtg tctatgcagt
   100921 cgcccttaac ccaaaaacag gtgcggtttt gtctatgtca gggattaaac atgacttgaa
   100981 aacaggagag ttgacgcctg attccttggg aacggtaacc aatgtctttg ttccaggttc
   101041 ggttgtcaag gcggcgacca tcagctcagg ttgggaaaat ggagtcttgt caggaaacca
   101101 gaccttgaca gaccagtcca ttgtcttcca aggttcagct cccatcaatt cttggtatac
   101161 tcaggcttac ggttcattcc ctatcacagc ggtccaagct ctggagtatt catcaaatac
   101221 ctatatggtc caaacagcct taggtcttat ggggcaaacc tatcaaccca atatgtttgt
   101281 cggcaccagc aatctagagt ctgctatgga gaaactgcgt tcaacctttg gcgaatatgg
   101341 cttgggtact gcgacaggaa ttgacctacc agatgaatct actggatttg ttcccaaaga
   101401 gtatagcttt gctaattaca ttactaatgc ctttgggcag tttgataact atacgccgat
   101461 gcagttggct cagtatgtag caactattgc aaatgatggt gttcgtgtgg ctcctcgtat
   101521 tgttgaaggc atttatggta ataatgataa gggaggactg ggtgacttga ttcagcaact
   101581 gcaaccgaca gagatgaata aggtcaatat atccgactcc gatatgagca tcttgcacca
   101641 aggtttttat caggttgccc atggtactag tgaattgaca actggacgtg ccttttcaaa
   101701 tggtgccttg gtatccatta gcggaaaaac aggtacagcc gaaagctatg tggcagatgg
   101761 tcagcaagca accaatacca atgcggtggc ctatgcccca tctgataatc cccaaatcgc
   101821 tgtcgcagtg gtctttcctc ataataccaa tctaacaaat ggtgtaggac cttccattgc
   101881 acgtgacatt atcaatctgt atcaaaaata ccatccaatg aactagaaag gaaattatgc
   101941 tttatccaac acctattgcc aagttgattg acagttattc taagttacca ggtatcggga
   102001 ttaagacggc tacgcgtctg gccttttata cgattgggat gtctgctgat gatgtcaatg
   102061 aatttgcaaa aaatctcctt tctgctaaga gagaattgac atattgttct atttgtggac
   102121 gtttgacaga cgacgatcct tgttctatct gtactgatcc gactcgtgac cagacaacaa
   102181 ttttagttct tgaggatagt agagatgtgg cagccatgga aaatatccaa gaataccatg
   102241 gactctatca tgtccttcat ggcctcattt ctcctatgaa tggtatcagt ccggacgata
   102301 tcaatctcaa gagccttatg actcgtctta tggatagtga ggtttcagaa gtgattgtgg
   102361 cgactaatgc tacagcggat ggtgaagcga cttccatgta tctttcacgt ttgctcaagc
   102421 cggctggtat caaggttacg cgtctagcac gaggtctcgc tgtgggagcg gacattgagt
   102481 atgcggacga agtgacactc ttacgagcca ttgaaaatcg gacagagttg taagtgtagg
   102541 caaatttacg aactccattc atttataaaa aatcaaagag gctggaaatc gttcctatcg
   102601 gcctcttttt gtatagtgtg atgagtagga tcaggttcaa gttttaaaaa accaagcaaa
   102661 tatgatatac taaagagcga gtattctagt agaattagga caaataatat gaaacaaacg
   102721 attattcttt tatatggtgg acggagtgcg gaacgcgaag tctctgtcct ttcagctgag
   102781 agtgtcatgc gtgcggtcga ttacgaccgc ttcacagtca agactttctt tatcagtcag
   102841 tcaggtgact ttatcaaaac acaggaattt agtcatgctc cggggcaaga agaccgtctc
   102901 atgaccaatg aaaccattga ttgggataag aaagttgcac caagtgctat ctacgaagaa
   102961 ggtgcagtgg tctttccagt ccttcacggg ccaatgggag aagatggctc tgttcaagga
   103021 ttcttggaag ttttgaaaat gccttacgtt ggttgcaaca ttttgtcatc aagtcttgcc
   103081 atggataaaa tcacgactaa gcgtgttctg gaatctgctg gtattgccca agttccttat
   103141 gtggctatcg ttgaaggcga tgatgtgact gctaaaatcg ctgaagtgga agaaaaattg
   103201 gcttatccag tcttcactaa gccgtcaaac atggggtcta gtgtcggtat ttctaagtct
   103261 gaaaaccaag aagaactccg tcaagcctta gaacttgcct tccgatatga tagccgtgtc
   103321 ttggttgagc aaggagtgaa tgcccgtgaa attgaggttg gcctcttggg taactacgat
   103381 gtcaagagca cgctaccagg agaagttgtc aaggacgttg ccttttatga ctacgatgcc
   103441 aagtatattg ataacaagat tactatggat attcctgcca aaatcagtga tgatgtggtg
   103501 gctgtcatgc gtcaaaatgc agaaacagcc ttccgtgcca ttggtggcct tggtctatct
   103561 cgttgcgatt tcttctatac agataaggga gagatttttc tcaacgagct caataccatg
   103621 ccaggtttca cccagtggtc tatgtaccca ctactttggg acaatatggg gatcagctac
   103681 ccagaactaa tcgagcgttt ggttgacctt gccaaggaaa gttttgacaa gcgcgaagcg
   103741 catttgatat aaaatgaaag agagggtaga agccagaacc atcactgcaa ggtgactaga
   103801 gttctcggac ttcagccctt tttaaaggag tagaaatgaa attaacaatc catgaaattg
   103861 cccaagttgt tggagccaaa aatgatatca gtatctttga ggacacccag ttagaaaaag
   103921 ctgagtttga tagtcgtttg attggaactg gagatttatt tgtgccactt aaaggtgcgc
   103981 gtgatggcca tgactttatt gaaacagcct ttgaaaatgg tgcagcagta accttgtctg
   104041 agaaagaggt ctcaaatcat ccttacattc tagtagatga tgttttgaca gcctttcaat
   104101 ccctagcatc ctactatctt gaaaaaacga ctgttgatgt ctttgctgtt acaggttcaa
   104161 atggcaagac aacgactaag gatatgttgg cgcatttact gtcaacaaga tacaagacct
   104221 acaaaacaca aggcaattac aataacgaga ttggccttcc ttacacagtt cttcatatgc
   104281 ctgaagggac agaaaagttg gtcttggaga tggggcagga tcacttggga gatattcatc
   104341 tcttgtctga actggctcgt ccaaaaacag ccatcgtgac cttggttgga gaagctcatt
   104401 tggccttttt caaagatcgt tctgagattg ctaaaggaaa aatgcaaatt gcggacggaa
   104461 tggcttcagg ttccttgctt ttagcgccgg ctgaccctat cgtagaggac tatttgccaa
   104521 ctgataaaaa agtggttcgt tttgggcaag gggcagagct ggaaattact gacttggttg
   104581 agcgcaaaga tagtctgacc ttcaaggcca atttcttaga gcaagccctt gatttgccag
   104641 taactggtaa gtacaatgct accaatgcta tgattgcatc ctatgttgcc ctacaagaag
   104701 gagtttcaga ggagcaaatc cgtttggcct tccaaggtct tgaattgacg cgtaatcgta
   104761 ctgagtggaa gaaagcagcc aatggagcag atatcctgtc agacgtatat aatgccaatc
   104821 caactgctat gaagctgatt ttagagactt tctctgccat tccagccaat gaaggtggca
   104881 agaaaattgc agtgttggcg gatatgaagg agcttggtga ccagtctatt caactccata
   104941 accagatgat tttgagcctt tcgccagatg tgcttgatac cgttattttc tatggagaag
   105001 acattgctga attagcccaa ttggccagtc aaatgttccc aattggccac gtttactact
   105061 tcaagaaaac agaagaccaa gaccaatttg aagacctagt caagcaggtc aaggaaagcc
   105121 tcagtgccaa tgatcaaatc ttgctcaagg gctctaactc tatgaaccta gccatgttgg
   105181 tagaaagttt agaaaatgaa accaagtgat tttgttaagt atctgcaaag aatgattgcc
   105241 cttacagata ctggcttaac ctttacaaaa gatccttttg accgtgagcg ctacgaggac
   105301 ttgcgaagtc tgttatctga aatgttgaat cagggatcag acctggatgc agaagaagta
   105361 gcagaagtct tgaaaccaac ttcagcttat gcgactccct taatggacgt ccgtgcttgg
   105421 attgttgagg atgagaagat ttgtctggtt aggggacaag gagaggatag ttgggctttg
   105481 ccaggtggct ttggtgaagt cggctattct ccaactgaaa atattctcaa ggaaattgaa
   105541 gaagaaaccg gttttaaagc caaagttgaa agactgctag ctgtttttga taccaatcgt
   105601 ttccaactac agagcaaaca atatgcaaag tttgtttttg aatgtaagct tctcgatgga
   105661 caattccaag aaaatcaaga aatcgctgac cttcaatttt ttgcaattga ccaactgccg
   105721 aatttatctg aaaaacgcat taccaaggag caaatagagc ttctttggca ggtttatcaa
   105781 ggtcagaggg agcaatatct tgactaagaa gatgattatc gtatttctaa attcattttt
   105841 cttaagtagc atggtataat aaaatgcagg aaaattttga atcatgagga agactagatg
   105901 aatttatggg atattttctt tacgactcag gcaaccgagc cgcccaaatt tgaccttttt
   105961 tggtatgtta gcctatttac gctcttagcc ttaacctttt atacagccca tcgctatcgt
   106021 gaaaagaagg tttaccaacg atttttccaa atcttgcaga ctgttcagtt aatccttctt
   106081 tatggttggt actgggtcaa tcatatgcca ctgtcagaaa gcctaccctt ttaccattgc
   106141 cgtatggcta tgtttgtggt actcttgctt cctggtcagt ccaaatataa acaatacttt
   106201 gcattattgg gaacatttgg gacattagca gcctttgttt atccagtgcc agatgcttac
   106261 ccttttccac atatcaccat tctatccttt atctttggtc atttagcact cttggggaac
   106321 tctctagttt atctattgag acagtataat gcgcgattgc tggatgtgaa gggaattttt
   106381 ctcatgacct ttgccctaaa tgccttgatt tttgtggtca atttggtgac aggtggcgat
   106441 tacggatttt tgacaaaacc gccattggtt ggggatcacg gtctagtagc taattattta
   106501 cttgtttcaa ttgtgctggt agctactatc agtttgacta agaaaatctt agaattcttt
   106561 ttagctcaag aagcagaaaa aatgattgca aaggaagctt aacacagagc tttctttttt
   106621 gctcttagag agtttttaca agcagcttat aaaataagaa tttctgaata gacaaactca
   106681 aaaaatggct gggaaattta ggaaaaaagc aagcacgatt aaattttttg tgttataata
   106741 ttttgtgaat agctatgcct atgtttagct atggaataat acgaagtgcg aaacttggaa
   106801 gatagagagg aagcgatgta atggctagag aaggcttttt tacaggtcta gatattggaa
   106861 caagctctgt caaggtgctt gtggccgagc agagaactgg tgaattaaat gtaattggcg
   106921 tgagtaatgc caaaagtaaa ggtgtaaagg atggaattat tgttgatatt gatgcagcag
   106981 caactgctat caagtcagcc atttcccaag cggaagaaaa ggcaggcatt tcgattaaat
   107041 cagtaaatgt cggcttgcct ggtaatcttt tgcaggtaga accaactcag gggatgattc
   107101 cagtaacatc tgatactaag gaaattacgg atcaagatgt tgaaaatgtt gtcaaatcag
   107161 ctttgacaaa gagtatgaca cctgaccgtg aagtcattac ctttattcct gaagaattta
   107221 ttgtggatgg tttccaaggg attcgtgacc cacgtggcat gatgggggtt cgccttgaaa
   107281 tgcgtggttt gctttataca ggacctcgta ctatcttgca caatttgcgt aagacggttg
   107341 agcgtgcagg tgttcaggtt gaaaatgtta tcatttcacc actagcaatg gttcagtctg
   107401 ttttgaacga aggggaacgt gaatttggtg ctacagtgat tgatatgggg gcaggtcaaa
   107461 cgactgtcgc tacaatccgt aatcaagaac tccagttcac acatattctc caagaaggtg
   107521 gagattatgt aactaaagat atctccaagg ttttgaaaac ctctcgcaaa ttagcggaag
   107581 gcttgaaact gaattacggg gaagcctatc cgcctcttgc aagcaaagaa accttccaag
   107641 tagaggttat tggagaagta gaagcagtcg aagtgacgga agcctacttg tcagaaatta
   107701 tttctgcacg aatcaagcac atccttgaac aaatcaagca agaattagat agaaggcgtc
   107761 tattggacct ccctggtggt attgtcttaa tcggtgggaa tgccatttta ccaggtatgg
   107821 ttgagcttgc tcaggaagtc tttggcgtcc gtgtcaagct ttatgttcca aatcaagttg
   107881 gtatccgtaa tccagccttt gcgcatgtga ttagtttatc agaatttgcg ggtcaattaa
   107941 cagaagttaa tcttttggct cagggagcga taaaaggtga gaatgactta agtcatcagc
   108001 caattagttt tggtgggatg ctgcaaaaaa cagctcagtt tgtacaatca acgcctgttc
   108061 aaccagctcc tgctccagaa gtagagccgg tggcgcctac agaaccaatg gcggatttcc
   108121 aacaagcttc acaaaataaa ccgaaattag cagatcgttt ccgtggcttg atcggaagca
   108181 tgtttgacga ataaagagga aaaataaatt atgacatttt catttgatac agctgctgct
   108241 caaggggcag tgattaaagt aattggtgtc ggtggaggtg gtggcaatgc catcaaccgt
   108301 atggtcgacg aaggtgttac aggcgtagaa tttatcgcag caaacacaga tgtacaagca
   108361 ttgagtagta caaaagctga gactgttatt cagttgggac ctaaattgac tcgtggtttg
   108421 ggtgcaggag gtcaacctga ggttggtcgt aaagccgctg aagaaagcga agaaacactg
   108481 acggaagcta ttagtggtgc cgatatggtc ttcatcactg ctggtatggg aggaggctct
   108541 ggaactggag ctgctcctgt tattgctcgt atcgccaaag atttaggtgc gcttacagtt
   108601 ggtgttgtaa cacgtccctt tggttttgaa ggaagtaagc gtggacaatt tgctgtagaa
   108661 ggaatcaatc aacttcgtga gcatgtagac actctattga ttatctcaaa caacaatttg
   108721 cttgaaattg ttgataagaa aacaccgctt ttggaggctc ttagcgaagc ggataacgtt
   108781 cttcgtcaag gtgttcaagg gattaccgat ttgattacca atccaggatt gattaacctt
   108841 gactttgccg atgtgaaaac ggtaatggca aacaaaggga atgctcttat gggtattggt
   108901 atcggtagtg gagaagaacg tgtggtagaa gcggcacgta aggcaatcta ttcaccactt
   108961 cttgaaacaa ctattgacgg tgctgaggat gttatcgtca acgttactgg tggtcttgac
   109021 ttaaccttga ttgaggcaga agaggcttca caaattgtga accaggcagc aggtcaagga
   109081 gtgaacatct ggctcggtac ttcaattgat gaaagtatgc gtgatgaaat tcgtgtaaca
   109141 gttgtcgcaa cgggtgttcg tcaagaccgc gtagaaaagg ttgtggctcc acaagctaga
   109201 tctgctacta actaccgtga gacagtgaaa ccagctcatt cacatggctt tgatcgtcat
   109261 tttgatatgg cagaaacagc tgaattgcca aaacaaaatc cacgtcgttt ggaaccaact
   109321 caggcatctg cttttggtga ttgggatctt cgccgtgaat cgattgttcg tacaacagat
   109381 tcagtcgttt ctccagtcga gcgctttgaa gccccaattt cacaagatga agatgaattg
   109441 gatacacctc catttttcaa aaatcgttaa gtaaatgaat gtaaaagaaa atacagaact
   109501 tgtttttcga gaagttgcag aggctagtct gagtgctcat cgagagagtg gttcggtctc
   109561 tgtcattgca gttaccaagt atgtagatgt accgacagcg gaagccttgc ttccgctagg
   109621 tgttcatcat atcggtgaaa atcgtgtaga taagtttctg gaaaaatatg aagctttaaa
   109681 agatcgagat gtgacttggc atttgattgg taccttgcaa agacgtaagg tgaaagatgt
   109741 cattcaatac gttgattatt tccatgcatt ggactcagta aagctagcag gggaaattca
   109801 aaaaagaagt gaccgagtca tcaagtgttt ccttcaagta aatatttcta aagaagaaag
   109861 caaacacggt ttttcgagag aggaactgct ggaaatcttg ccagagttag ccagactaga
   109921 taagattgaa tatgttggtt taatgacgat ggcacctttt gaggctagca gtgagcagtt
   109981 gaaagagatt ttcaaggcga cccaagattt acaaagagaa attcaagaga aacaaattcc
   110041 aaatatgcct atgaccgagt taagtatggg aatgagtcgt gattataaag aagcgattca
   110101 attcggttcc acttttgttc gtataggtac atcatttttt aagtaggaga gaaccatgtc
   110161 tttaaaagat agattcgata gatttataga ttattttacg gaggatgagg attcaagtct
   110221 cccttatgaa aaaagagatg agcctgtgtt tactccagta aattcttcac aggaaccggc
   110281 tctcccaatg aatcaacctt cacagtcggc tggtacaaaa gagaacaata tcaccagact
   110341 tcatgcaaga caacaggaat tggcaaatca gagtcagcgt gcaacggata aggtcattat
   110401 agatgttcgt tatcctagaa aatatgagga tgcaacagaa attgttgatt tattggcagg
   110461 aaacgaaagt atcttgattg attttcagta tatgacagag gtgcaggctc gtcgttgttt
   110521 ggactatttg gatggagctt gtcatgtttt agctggaaat ttgaaaaagg tagcttctac
   110581 catgtatttg ttgacaccag tgaatgttat tgtaaatgtt gaagatatcc gtttaccaga
   110641 tgaagatcaa cagggtgagt tcggttttga tatgaagcga aatagagtac gataatgatt
   110701 tttttaattc gtatgattta taatgcagtg gatatttact ccctgatttt ggtagccttc
   110761 gctgtcatgt cttggtttcc aggtgcctac gaatccagtt taggtcgttg gattgtagcg
   110821 ttggtgaaac cagtgcttgc tcccttgcaa cgcctgcctt tacagatagc gggtcttgat
   110881 ttatctgttt gggtcgcgat tgttttggtt cgatttttag gagaaaacct agtgcgtttt
   110941 ctggcgatga taggatgaat aaagggattt attagcattt ctccatagaa gatcgtccat
   111001 ttcttgacaa gggaatggaa tggataaaga aggtagaaga tagctatgct ccttttttaa
   111061 ctccttttat caatcctcat caggagaagc tattaaagat tttggccaaa acctatggtc
   111121 ttgcttgtag cagtagtggg gaattcgtct cgagtgagta tgttcgagtt ttattatacc
   111181 cagattattt ccaaccagag ttttcagatt ttgaaatatc tctccaggaa attgtgtatt
   111241 ccaataaatt tgaacattta acgcatgcta agattttagg gacagtcatc aatcaattag
   111301 ggattgaacg gaaacttttt ggagatatcc tagtagatga agaacgggcg cagattatga
   111361 ttaatcagca gtttcttctt ctctttcaag atggactaaa gaaaattggt cgtatacctg
   111421 tttcgctgga ggaacgtcct ttcaccgaga aaatagataa gctagaacag tatcgagaac
   111481 tggatttatc tgtgtctagt tttcgattag atgttctttt atcaaatgtt ttgaaactat
   111541 ctaggaatca agcaaaccag ttgattgaaa agaaacttgt ccaagtaaat tatcatgtgg
   111601 tagacaaatc agattacact gttcaagttg gagacttgat tagtgtgaga aaatttggtc
   111661 gcttgagatt acttcaagat aagggacaaa cgaaaaaaga gaagaaaaaa ataaccgtcc
   111721 agttattatt aagtaagtga ggaatagaat gccaattaca tcattagaaa taaaggacaa
   111781 gacttttgga actcgattca gaggttttga tccagaagaa gtcgatgaat ttttagatat
   111841 tgtggttcgt gattacgaag atcttgtgcg tgcgaatcat gataaaaatt tgcgtattaa
   111901 gagtttagaa gagcgtttgt cttactttga tgaaataaaa gattcattga gccagtctgt
   111961 attgattgct caggatacag ctgagagagt gaaacaggcg gcgcatgaac gttcaaacaa
   112021 tatcattcat caagcagagc aagatgcgca acgcttgttg gaagaagcta aatataaggc
   112081 aaacgagatt cttcgtcaag caactgataa tgctaagaaa gtcgctgttg aaacagaaga
   112141 attgaagaac aagagccgtg tcttccacca acgtctcaaa tctacaattg agagtcagtt
   112201 ggctattgtt gaatcttcag attgggaaga tattctccgt ccaacagcta cttatcttca
   112261 aaccagtgat gaagccttta aagaagtggt tagcgaagta cttggagaac cgattccagt
   112321 tccaattgaa gaagaaccaa ttgatatgac acgtcagttc tctcaagcag aaatggaaga
   112381 attacaagct cgtattgagg tagccgataa agaattgtct gaatttgaag ctcagattaa
   112441 acaggaagtg gaagctccaa ctcctgtagt gagtcctcaa gttgaagaag agcctctgct
   112501 catccagttg gcccaatgta tgaagaacca gaagtagctc cagtgcatcc gacaggtcca
   112561 acaccagcta cagaaactgt tgattcagca ccgggatttg aagcaccgca agaatctgtt
   112621 acaattttat aagaaatatt ctgagaacaa tatcttatcc ttatattccc agcgagcagg
   112681 agatggtgtg agtcctgcat tccctatcga taagattatc ctctcaaaaa ctcaagtctg
   112741 aatctagtaa gatttgacgt tccccacgtt acgggataag agggagaaag actaaaactt
   112801 tttccgaata aaggtggtac cacgattttc gtcctttttg gaagttgtgg tttttaattt
   112861 gttattattt ataaaggaga taccatgaaa ctcaaagaca cccttaatct tgggaaaact
   112921 gaattcccaa tgcgtgcagg ccttcctacc aaagagccag tttggcaaaa ggaatgggaa
   112981 gatgcaaaac tttatcaacg tcgtcaagaa ttgaaccaag gaaaacctca tttcaccttg
   113041 catgatggcc ctccatacgc taacggaaat atccacgttg gacatgctat gaacaagatt
   113101 tcaaaagata ttattgttcg ttctaagtct atgtcaggat tttacgcacc atttattcct
   113161 ggttgggata ctcatggtct gccaatcgag caagtattgt caaaacaagg tgtcaaacgt
   113221 aaagaaatgg acttggttga gtacttgaaa ctttgccgtg agtacgctct ttctcaagta
   113281 gataaacaac gtgaagattt taaacgtttg ggtgtttctg gtgactggga aaatccatat
   113341 gtgaccttga ctcctgacta tgaagcagct caaattcgtg tatttggtga gatggctaat
   113401 aagggttata tctaccgtgg tgccaagcca gtttactggt catggtcatc tgagtcagcc
   113461 cttgctgaag cagagattga ataccatgac ttggtttcaa cttcccttta ctatgccaac
   113521 aaggtaaaag atggcaaagg agttctagat acagatactt atatcgttgt ctggacaacg
   113581 actccattta ccatcacagc ttctcgtggt ttgacggttg gtgcagatat tgattacgtt
   113641 ttggttcaac ctgctggtga agctcgtaag tttgtcgttg ctgctgaatt attgactagc
   113701 ttgtctgaga aatttggctg ggctgatgtt caagttttgg aaacttaccg tggccaagaa
   113761 ctcaaccaca tcgtaacaga acacccatgg gatacagctg tagaagagtt ggtaattctt
   113821 ggtgaccacg ttacgactga ctctggtaca ggtattgttc atacagcccc tggttttggt
   113881 gaggacgatt acaatgttgg tattgctaat aatcttgaag tcgcagtgac tgttgatgaa
   113941 cgtggtatca tgatgaagaa tgctggtcct gaatttgaag gtcaattcta tgaaaaggta
   114001 gttccaactg tgattgaaaa acttggtaac ctccttcttg cccaagaaga aatctctcac
   114061 tcatatccat ttgactggcg tactaagaaa ccaatcatct ggcgtgcagt tccacaatgg
   114121 tttgcctcag tttctaaatt ccgtcaagaa atcttggacg aaattgaaaa agtgaaattc
   114181 cactcagaat ggggtaaagt ccgtctttac aatatgatcc gtgaccgtgg tgactgggtt
   114241 atctctcgtc aacgtgcttg gggtgttcca cttcctatct tctacgctga agatggtaca
   114301 gctatcatgg tagctgaaac tattgaacac gtagctcaac tttttgaaga acatggttca
   114361 agcatttggt gggaacgtga tgccaaagac ctcttgccag aaggatttac tcatccaggt
   114421 tcaccaaacg gcgagttcaa aaaagaaact gatatcatgg acgtttggtt tgactcaggt
   114481 tcatcatgga atggagtggt ggtaaaccgt cctgaattga cttacccagc cgacctttac
   114541 ctagaaggtt ctgaccaata ccgtggttgg tttaactcat cacttatcac atctgttgcc
   114601 aaccatggcg tagcacctta caaacaaatc ttgtcacaag gttttgccct tgatggtaaa
   114661 ggtgagaaga tgtctaaatc tcttggaaat accattgctc caagcgatgt tgaaaaacaa
   114721 ttcggtgctg aaatcttgcg tctctgggta acaagtgttg actcaagcaa tgacgtgcgt
   114781 atctctatgg atattttgag ccaagtttct gaaacttacc gtaagattcg taacactctt
   114841 cgtttcttga ttgccaatac atctgacttt aacccagctc aagatacagt cgcttacgat
   114901 gagcttcgtt cagttgataa gtacatgacg attcgcttta accagcttgt caagatcatt
   114961 cgtgatgcct atgcagactt tgaattcttg acgatctaca aggccttggt gaactttatc
   115021 aacgttgact tgtcagcctt ctaccttgat tttgccaaag atgttgttta cattgaaggt
   115081 gccaaatcac tggaacgccg tcaaatgcag actgtcttct atgacattct tgtcaaaatc
   115141 accaaactct tgacaccaat ccttcctcac actgcggaag aaatttggtc atatcttgag
   115201 tttgaaacag aagacttcgt ccaattgtca gaattaccag aggctcaaac ttttgctaat
   115261 caagaagaaa tcttggatac atgggcagcc ttcatggact tccgtggaca agctcaaaaa
   115321 gccttggaag aagctcgtaa tgcaaaagta atcggtaaat cacttgaagc acacttgaca
   115381 gtttatccaa acgaagttgt gaaaactcta ctcgaagcag taaacagcaa tgtggctcaa
   115441 cttttgatcg tgtcagactt gaccatcgca gaaggaccag ctccagaagc tgcccttagc
   115501 ttcgaagatg tagccttcac agttgaacgc gctgcaggtg aagtatgtga ccgttgccgt
   115561 cgtattgacc caacaacagc agaacgtagc taccaggcag ttatctgtga ccactgtgca
   115621 agtatcgtag aagaaaactt tgcagatgca gtcgcagaag gatttgaaga gaaataagat
   115681 tgaaaagtct aggcaaaatt caatttgaga agaaaagaca actaatttta tagtctatta
   115741 aacgcattgt atcacgtttt tgaacacctg atatgatgcg ttttttattt ttaaaatttg
   115801 caaggtgtga ctttttatac tcatactcaa tgaaaatcaa aaagcaaact aggaagctag
   115861 ccgcaggctg ctcaaaacac tgttttgagg ttgtagataa gactgacgaa gtcagtaaca
   115921 tatatatggt aaggcgacgc tgacgtggtt tgaagagatt ttcgaagagt atcaacaaga
   115981 atcaaagaga aacttagcaa gctaacagta gtaagataaa ataggaattt gatattaggg
   116041 ataagattgg taaatagtgt aatattttta caacaataaa tttatatagt tatttctggt
   116101 ttctgaaaag tattatatta tattttattt catattatac aaatttttat tttataatat
   116161 cagaaaatac tttttttaaa aagcaaatat gatacaattt tatttgaaaa aaaataaaaa
   116221 aggagatttt attatgaaat caagtggtat cgtcggtctt gtgggaggaa ttttacttct
   116281 tatttgtcct tttgtcttgt tgggaacagc ggtaaataca gctgctacaa ctcttaatgg
   116341 aggagctact gcaggggctt tttcaggtgt tgccttactc ttgaatacct tgaagattgc
   116401 aaatcttgtt cttggtatca ttgctattgt ttactataaa ggagataagc atgtaggtgc
   116461 agctccgtct gtactaatga ttgtttctgg tgaagttagt ctcattccat tcttaggatg
   116521 agttgggggg attcttgcta ttatcggagg atctctattc cttgcaacat tgaagaaatt
   116581 caaatcagaa gaataaaagg tattttagca tgaaaagaac aaaaaagttt atcggtatag
   116641 gagtagctct attatctctt tctcttctag ttgcatgtgg aacataaagt tcaaagaata
   116701 cttcaacaag taatgatgag aagacagtag caacatccaa tagttcaaaa gaaacaatca
   116761 ctttcgatac accggttgta acagacgatg cgattgaatc aatacgcact tatgcagatt
   116821 atatagatct ttataaaaat atttttgatg attattttac taaagctgag gaaggtttca
   116881 aaggcacagt tatggaaaat aatgactcgt ttactaaact aaaagagtca actcaaaaat
   116941 tattcgatgc gcagaaaaaa aggttaaata atgaagatag aatagaaaca gccaaaaaca
   117001 atgtgattgc caaacattgt caaacagtcc tttccttttt ggttttgact agcttttttg
   117061 tgaaaaattg tgtaaaatag aatagataaa cgaggggaaa cctcggaaaa tttaaaggag
   117121 aatccatcta atggtaaaat tggtttttgc tcgccacggt gagtctgaat ggaacaaagc
   117181 taaccttttc actggttggg ctgatgttga tttgtctgaa aaaggtacac aacaagcgat
   117241 tgacgctggt aaattgatca aagaagctgg tatcgaattt gaccaagctt acacttcagt
   117301 attgaaacgt gctatcaaaa caactaactt ggctcttgaa gcttctgacc aattgtgggt
   117361 tccagttgaa aaatcatggc gcttgaacga acgtcactac ggtggtttga ctggtaaaaa
   117421 caaagctgaa gctgctgaac aatttggtga tgagcaagtt cacatctggc gtcgttcata
   117481 cgatgtattg cctccaaata tggaccgtga tgatgagcac tcagctcaca cagaccgtcg
   117541 ttatgcttca cttgacgact cagtaatccc agatgctgaa aacttgaaag tgactttgga
   117601 acgtgctctt ccattctggg aagataaaat cgctccagct cttaaagatg gtaaaaacgt
   117661 attcgtagga gctcacggta actcaatccg tgcccttgta aaacacatca aaggtttgtc
   117721 agatgatgag atcatggacg tggaaatccc taacttccca ccattggtat tcgaattcga
   117781 cgaaaaattg aacgttgttt ctgaatacta ccttggaaaa taaaaaattg taagcctagg
   117841 attgatttct aggcttttta tgttagtatg gaagtatgat aaggaataaa aaacaagatt
   117901 atgtactggc ctacaaacaa ccagcttcaa ccacttacat gggttgggaa gaagaagctt
   117961 taccgatagg taatggttct ttaggagcaa aagtatttgg ccgtataggg gctgaacgga
   118021 ttcaatttaa tgaaaaaagt ctctggtctg gaggtccact tcctgatagt tcagattatc
   118081 agggtggaaa tcttcaggat cagtatgttt ttttagctga gattcggcag gctttggaga
   118141 agagagatta caatctggct aaggaactgg ctgagcagca cctaattggg ccaaaaacga
   118201 gtcaatatgg gacctatctg tcttttgggg atattcacat tgagttcagc cagcaaggta
   118261 cgactttgtc tcaggtgacg gactatcaga gacagctgaa tattagtaag gcacttgtga
   118321 cgacttctta tgtctataag ggaacgcgat ttgaacgtga agcttttgcg agttttccag
   118381 atgatctctt ggttcagcgt tttactaagg aaggggcgga aactctagat tttactatag
   118441 aactatcctt gacctgtgat ttggcttctg atgaaaagta tgagcaggaa aaatctgatt
   118501 acaaggagtg taagttggat attactgatt ctcatatctt gatgaaggga agagttaagg
   118561 ataatgatct gcggtttgct agttatctag cttgggaaac ggatggagat attagagttt
   118621 ggtcagatag ggttcagata tcaggagcca gttatgccaa tctcttcttg gccgctaaga
   118681 cggattttgc ccaaaatcct gctagcaatt atcgcaagaa actagattta gagcaacagg
   118741 tgatagactt ggtggacaca gctaaagaaa agggctatac ccaattgaaa tcaaggcata
   118801 tcgaggacta ccaagcctta ttccagcgtg ttcaattgga tttggaagct gatgttgacg
   118861 catccactac agatgatttg ttaaaaaatt ataagccaca agaagggcag gctttggagg
   118921 agctgttctt ccagtatgga cggtatttat tgattagttc gtccagagac tgcccagatg
   118981 ctctaccagc taacctacag ggagtctgga atgcggtcga caatcctcct tggaattcgg
   119041 actatcactt aaatgtcaat ctgcagatga attattggcc agcctatgtt accaatctcc
   119101 tagaggcggt ctttccggtc atcaactatg tagatgattt gcgtgtctat ggtcgtctag
   119161 cggctgtaaa gtatgcagga atcgtctctc agaaaggtga ggaaaatggt tggttggttc
   119221 atactcaagc gactcccttt ggttggacgg cacctggttg ggattactat tggggttggt
   119281 caccagctgc caatgcgtgg atgatgcaaa ccgtttatga agcctattca ttttataggg
   119341 accaagacta tctcagggag aaaatttatc ccatgttgag ggaaacggtt cgtttttgga
   119401 atgccttttt acataaggat cagcaggcgc agcgttgggt gtcttctccg tcttattctc
   119461 cagaacatgg gccgatttcg attggcaata cctatgacca atctctgatt tggcagttat
   119521 ttcatgattt tattcaggct gctcaggaat tgggactgga tgaggacttg ttgactgagg
   119581 ttaaggagaa gtctgattta ctaaatcctt tgcaaatcac tcaatctggt cgaatcaggg
   119641 agtggtatga ggaggaagag cagtattttc aaaatgagaa agtggaggcc cagcaccggc
   119701 acgcttccca tctagtggga ctctatcctg gcaatctctt tagctacaag ggacaagagt
   119761 atattgaagc ggcgcgtgct agcctcaatg atcgtggaga tggcggcaca ggctggtcca
   119821 aggctaataa gatcaatctc tgggcgcgtt tgggagatgg caatcgagcc cataaattat
   119881 tggcagagca gttaaagaca tccaccttgc caaatctttg gtgtagccat cctccttttc
   119941 agatagatgg taattttggt gctactagtg gcatggcaga aatgttactc cagtctcatg
   120001 cagcttatct ggtacctcta gctgccctac ctgatgcttg gtcaacaggt tctgtttcag
   120061 gcttaatggc acgtggacat tttgaagtga gcatgagctg ggaagataaa aaactcttac
   120121 agttgaccat tttatcaagg agtggaggag atttgcgagt ttcttatcca gatattgaga
   120181 agagtgtgat taaaatgaat caagaaaaaa taaaagcgaa atgcatgggg aaagattgta
   120241 tttcggtggc aacagcagaa ggtgatcttg ttcaatttta tttttaagaa gatgttataa
   120301 ggcagtaatt tgaaactgcc ttttaataag gatttaagaa tataagcagt tttcaactag
   120361 ttgaaaaagc gttataatga taataggaag taatactcaa tgaaaatcaa agagcacaaa
   120421 caaggaagct agccgcaggt tgctcaaaac agtgttttga ggttgcagat ggaagctgac
   120481 gtggtttgaa gagagatttt cgaggagtat aatttgtttg atagagggtg ggtctgatgg
   120541 cttatattga gatgaaacac tgttacaagc gttatcaggt tggggacacg gagattgtgg
   120601 ccaatcgtga tgtgaatttt gagattgaaa agggggagct ggttattatc cttggtgctt
   120661 caggtgcagg caagtcaaca gtgcttaacc ttcttggggg aatggatacc aatgatgaag
   120721 gggaaatctg gattgatggt gttaatattg cggattatag ttcccaccag cgcaccaatt
   120781 accgtagaaa tgatgtgggg tttgtttttc agttttataa tctagtttct aatctgacag
   120841 ctaaggaaaa tgtggaactg gcttctgaaa ttgtgacaga tgccttgaat cctgatcagg
   120901 tcttgacaga tgtaggtctg gctcatcgtc taaataactt tccagcccag ctttctggag
   120961 gggagcaaca gcgagtctcc attgcacgcg cggtagccaa aaatcctaaa attcttcttt
   121021 gtgatgaacc tactggagcc ttggattatc agacgggcaa gcaggttttg aaaattctcc
   121081 aagatatgtc tcgtcaaaag ggagcgacgg tgatcatcgt gactcataat ggagctttgg
   121141 cgcccattgc tgatcgcgtg attcatatgc acgatgccag tgtcaaggat gtggtgctca
   121201 accagcatcc tcaggatatt gacagtttgg agtactagta tgatcaagcg aaaaacttat
   121261 tggaaggact taattcagtc cttcacaggc tccaaggggt gttttttatc catcttgatc
   121321 ctgatgatgt tgggatctct agccttagta ggcctcaaag taaccagtcc caacatggag
   121381 gcgacagcta atgcttattt aacaactgct caaaccttgg atttggcagt catgtctaac
   121441 tatggcttgg atcaagcaga ccaagaagaa ctaaaacaga cggagggcgc agaggtcgag
   121501 tttggctatt tgacagatgt gactatggat aatgggcagg atgccattcg gctgtactcc
   121561 aaaccagagc gaatttcaac ctttcagcta agaaagggac gacttcctca gtcagacaag
   121621 gaaatcgctt tggccactca tttgcaaggc caatacagcg tgggacagga gattagtttt
   121681 aaagaaaaag aagagggtca ttcctcttta aaagaccata cttataccat tactggtttt
   121741 gtggattcgg ctgaaatcct ctcccagcga gatatgggct acgcaggaag tggaagtggg
   121801 actctgacag cctatggggt gattttacct agtcagtttg atcagaaagt ctacaatata
   121861 gctcgtttga aatatcaaga tttagcaggt ttaaatgtct tttcatcagc ttatgaagaa
   121921 aaatccaagc aacatcagga agagcttgaa caaattttat cagataatgg caaggtacgt
   121981 ctgcaacttt tgaaaaaaga aggacaagag tctctagaca aggggcaaga gacccttgac
   122041 aaggctcaga ctaatttgca ggaaggcaag cgtcgtttag cagctgctca agctcgtata
   122101 caggctcaag aaagtcaact agccttgttt cctcaagttc agagagagca ggctagtgct
   122161 caacttaccc aagccaagca ggaattgggc aaggaagagg acaaactaaa gcaagctgaa
   122221 caaaatctag cccaagaaaa ggaaaaatta gaaaaacatc agcaagtctt ggacgatttg
   122281 gcggagccaa ggtatcaggt ctataatcgt cagaccatgc caggtggtca gggctatctt
   122341 atgtatagca atgcttcatc cagtattcga gcagtgggca atatctttcc tgtggtactt
   122401 tatgccgtag cagccatggt gacctttacg accatgactc gctttgtaga cgaagagcga
   122461 actcatgcag ggatttttaa ggccttgggt tatcgtagta aggatattat cgccaagttt
   122521 ctcctttatg gactagtagc tgggactgtc ggaacggctc taggtagtat acttggtcat
   122581 tatttgctag ccagtgtaat ttcaagtgtc attacaaaag gcatggtggt gggagaaacc
   122641 cagattcagt tctattggac ctatagctta ctagcttttg tcttgagctt gttggcgagt
   122701 gtgttaccag cctatctggt ggcttggagg gaacttcatg acgaagcagc ccagcttcta
   122761 cttcctaaac ctcctgtcaa aggagctaaa atcttattgg agcgtatcgg ttttatctgg
   122821 cgtcgtctca gttttactca taaggtaaca gcccgcaaca tctttcgtta taagcagaga
   122881 atgttgatga caatctttgg tgtggcaggt tctgtagctc tgctctttgc aggtttggga
   122941 atccaatctt ctgtagcagg agttccgtct aaacagtttc aacaaatcca acagtatcag
   123001 atgcttgtct ctgaaaatcc tagtgcgacc aatcaggaca aggtagagct agcagaagtg
   123061 ttgaaagggc aggagatact agcctaccag aaaatctatt ctaaagcgct atacaaggat
   123121 ttcaaaggca aagctggtct tcaaaacatt actcttatga tgatagagaa ggaagatttg
   123181 actcccttta tccatcttca acatcatcag caggagctga cattaaaaga tggcatcgtt
   123241 attacagcta aactcgccca gctggcaggt gtcaaggttg ggcagacttt agaaattgaa
   123301 ggtaaggaac taaaggtcgc tgctattact gagaactacg ttggtcactt tatttatatg
   123361 agtcaggcta gctatgagca actttacgga cagctacccc aagccaacac ttatctggtc
   123421 tcattaaggg ataccagtgc aactagtatc gaaagtcagg cgggcttgct tatgaatcaa
   123481 tctgcggtgt ccagcgttgt ccaaaatgct tcagccattc gactcttcga ctctatcgct
   123541 agctcactca atcagaccat gaccatcttg gtcatcgtat cggttctatt agctattgtc
   123601 atcctttaca atctgaccaa tatcaacgta gctgagagaa tccgtgaact ctccactatc
   123661 aaggttcttg gttttcataa taatgaagtc accctctaca tttaccgtga gacgattgtg
   123721 ctgtcccttg tgggaatcgt acttggtctg atagctggtt tctatttaca ccaatttttg
   123781 attcaaatga tttcgcctgc gactattctc ttttatccgc aggtaggctg ggaagtctat
   123841 gtaatcccag tggcagcagt aagcatcatt ttgaccttgc ttggtttctt cgtcaattat
   123901 tatctgagaa aggttgatat gttagaagcc ctgaaatctg tagagtaagg tagttatttt
   123961 tagctgattg aacttctatt tactaatatt caaaaatcct ccgtttcaaa gagcagggaa
   124021 ctctttgtga cagaggattt tttctatagg gctttagcag ctgcaattgc ggcttcgaag
   124081 tttggctcag aattgatatt atccacgtat tcaacgtagc gaatcgtatt gtcagtatcg
   124141 aggacaaaga ctgcgcgtgc taataggtgc cattcgttga tcaagagggc ataatcgtgc
   124201 ccgaaagaat ggtcaaagta gtctgaaagc ataatggcat tgtcaaggcc ttcagcaccg
   124261 caccaacgtt tttgagcaaa aggtaggtcc attgaaacag tcaatacgac cgtgttgtcc
   124321 agtccagcca attcttcatt aaaacgacgt gtttgagttg agcagatgcc tgtatcgata
   124381 gaaggaacga cactcaagac ttttttcttg ccatcaaaat cagccagaga ttttttagaa
   124441 agatctgttg tagtaagaga aaaatcaagc gccttgtcgc cgacttgtag ttgtttacct
   124501 gtaaagctca caggatttcc gagaaaagtt accataggat actccaatct tttttcttcc
   124561 attgtatctg aaacagtcag aattttccaa tgatttgacc ggaaatgtgg gcatagaaaa
   124621 aacgccagct catatgagaa tgacgttttt cagaggctta ttttgccaat ccttcagcaa
   124681 tcttgtcaag gttgtatttc atcatgctgt agtagctgtc gccttcttta ccttgttctg
   124741 cgatagagtc agtaaagatt tgtgcgtaga ttgggatgtt tgtgtcttga gaaacggttt
   124801 tcattggacg gtcatccaca cttgattcta caaagagtga tggaactttt gtttggcgaa
   124861 gtttttcaac caaggtcttg atttgttcag gagttccttc ttcttcagta ttgatttccc
   124921 agatgtaggc acttggaaca ccataggctt tagagaagta tttgaatgct ccttcgctgg
   124981 ttacaatgag tttcttttca gcagggatct tattaaattt atccttactt tctttatcaa
   125041 gtttgtctaa cttatcagta tattctttga gatttttttc atagaattct ttattgttag
   125101 ggtctttggc gctcaattgt ttggcgatat ttttagcaaa aataataccg ttttcaaggt
   125161 taagccaagc gtgtgggtct tcttttcctt tttcattttg accttcaagg tagataacat
   125221 caacgccgtc gctgactgcg aagtagtctt tgttttcagt tttcttggca ttttctacca
   125281 attttgtaaa ccaagcattg ccacctgttt caaggttgat accgttatag aaaatcaaat
   125341 cagcctcaga agttttctta acgtcttcag gaagtggttc gtattcgtgt gggtcttgcc
   125401 caatcggaac gatactatga aggtcaattt tgtcaccagc aatattttta gtaatatcag
   125461 cgatgattga gtttgtagca acaactttta gtttttgacc agaagttgtt gctttttttc
   125521 cgctagcaca tgctacaaga atgattgcag aaagaaagag aacgagtaat gtacctaatt
   125581 ttttcattag atcctccaat ttattagggc tttgcccctt attttaacaa atgtttattt
   125641 ttcagtttca aatatcgttg tttgggagcg ataaagaagc taatgagaaa gaaactagca
   125701 gctgtaagca cgatactaga acctgccgca acattaaaac tatagccaat aaagagtccc
   125761 aaaactgaag cagtagctcc gaaggttgag gaaaggaaaa tcatgctttt cagactatta
   125821 gcatacagat aagcagttgc agctggggta atcagcatgg ctacaatcag gatagttccg
   125881 acactttgca tggctgtcac agacacgaga gtcaggagta ccatgagaag gtagtgatag
   125941 aaattgacag gcattcccat ggctttagcc aagagttcat caaaggaagt tatcaagagt
   126001 tgcttgaaga aaatccagat taacaagagg atggctgccc ccacacccat agtaataaac
   126061 atatccgtat cttggacggc caggatatta ccaaaaagga tatggaaaag gtcagttgaa
   126121 cttttagcga caccaatcaa gatgataccg agggctaaga aagaagaaaa ggtaatgccg
   126181 atggcggtat cgcttttgat aatcgagttt cctttgatgt aggtaatgat gatggcagct
   126241 agcaatccaa agacaatggc tccgataaag aagtcaaggc ccaagatgaa ggagagggct
   126301 acacctggta agacagcatg tgaaatggca tctcccatga gtgacatccc gcgtagaata
   126361 atgaaacatc ccacggctcc agctacaatc ccgacgacaa tagctgttat caaggcattt
   126421 tgtaggaaat ggaatttttg caatccatcg ataaattctg caatcatagg tcacctccat
   126481 tgaaaaagag ttgattaccg taagcttctt ttagattggt ttcggtaaaa gtttcttttg
   126541 ttggaccaaa ggcaatcact tctcgattga caagtaagac ttgatcgaag tagtggggaa
   126601 tcttgctgag gtcgtggtga acgatgagaa ccgtcttccc agcttttttc aaatctctca
   126661 gcgtattcat gatgatttcc tcactgacag agtcaatccc agcaaagggt tcatccaaga
   126721 ggatatagtc ggcttcctgc accaaacatc tggcaatcaa gacccgctgg aattgacctc
   126781 cagacagttg actaatttga cgttcagcgt agtcagctag gccgacgatt tcaagggcct
   126841 cttgcacttt cttccaatgt ttagccttta aacttcgaaa gagaggaata gagggaaata
   126901 gtcctaacga gacgcattcc ttgaccttga tgggaaagtt gtagtcgata ttgatttttt
   126961 gttcgacata ggcaattcgg tgtaaggatt ttttaacttc cttgtcatcg agaaatgcct
   127021 gaccttgatg tgggataatt cccagcatac cttttaatag tgttgatttc ccagcgccgt
   127081 ttggaccaat gatgccggta attgttggtc catggagcac tagtgaaata tccttaagtg
   127141 ccaacgtttc tttgtaggag acactgaggt tttctatacg tatcataaac ttgtattcct
   127201 cctgtctctt aatatacatt aaaaaaaaaa ttaagtcaag ttaatttttg aaaaaattaa
   127261 aataataact gaaaaataga ttctaaagat aactttcagg ataaatttct aaattataaa
   127321 acgcatagta tcaagtgtaa aaaacttgga attatgcgtt ttatcatgga aagatttttt
   127381 ataatagcta aaaaataata gttaaatggt tattaattgc attccctagt gatttttgtt
   127441 aagataaatg caaatacaaa tgaaagcgag aacaagatga cacgttatca agatgatttt
   127501 tatgatgcta tcaatggaga atggcaacag acagctgaaa tcccagcaga taagtctcaa
   127561 actggaggtt ttgttgattt agaccaggaa attgaagacc tgatgctggc gacaacagac
   127621 aagtggttag caggtgaaga agtgcctgag gatgctatct tggaaaactt tgtcaaatac
   127681 caccgcctag ttcgtgattt tgacaagaga gaagctgacg gtatcacacc tgtcttacca
   127741 ctccttaaag aattccaaga attggaaact tttgcggatt ttacagctaa actagcagag
   127801 tttgagcttg caggaaaacc aaacttcctt ccttttggtg tatcgccaga ctttatggat
   127861 gctagaatca atgttctatg ggctagcgct ccaagcacaa tcttgccaga tacgacctac
   127921 tatgcagaag aacatcctca gcgcgaagag ctcttgactc tttggaaaga aagcagcgca
   127981 aatctcctca aggcttatga tttctctgat gaagaaattg aagacttgct agaaaaaaga
   128041 cttgaattgg accgccgagt tgcgacagtg gtgctctcta atgaagaaag ttcagaatat
   128101 gctaaactct atcatccata ttcttacgaa gatttcaaga aattcgcgcc tgccctacct
   128161 ttggatgact tcttcaaagc agttattggg caattaccag acaaggttat tgtagacgag
   128221 gaacgtttct ggcaagcagc agagcaattc tacagtgagg aagcctggtc tctccttaaa
   128281 gcaaccttga ttttgagtgt tgtcaatctt tcaaccagct atttaacaga ggatatccgt
   128341 gttttgtctg gtgcctacag ccgtgccctt tctggagttc cagaggcaaa agataaggtc
   128401 aaagcagctt atcatctagc acaggaacct ttcaagcaag ccctggggct ttggtacgcc
   128461 cgtgagaagt tctctccaga agccaaggcg gatgtggaga aaaaagtggc aaccatgatt
   128521 gatgtctata aggagcgtct gcttaagaat gactggctca ctccagaaac ctgtaaacag
   128581 gctatcgtga agctcaatgt gatcaaacct tatattggct atccagaaga attgcctgca
   128641 cgttacaagg ataaggtagt gaatgaaact gccagtcttt ttgagaatgc tctagccttt
   128701 gcgcgtgtgg aaatcaagca cagttggagt aagtggaacc agcctgtaga ctataaggaa
   128761 tggggcatgc ctgctcatat ggtcaatgcc tactacaatc ctcagaagaa cctgattgtc
   128821 tttccagcgg ccattttaca ggcgcctttc tatgacttgc atcagtcatc ttctgctaac
   128881 tacggtggta ttggggcagt gattgcccat gaaatttccc acgcctttga tactaacggg
   128941 gcttcctttg acgaaaatgg tagcctcaag gattggtgga cagagagcga ctatgctgcc
   129001 ttcaaggaga aaacacaaaa agtcattgac caatttgatg gacaggattc ttatggagca
   129061 accattaacg gtaaattgac tgtatcagaa aacgtggctg acttgggagg aatcgcagca
   129121 gcgcttgaag cagctaagag agaagcagac ttctcagcag aagagttctt ctacaacttc
   129181 ggtcgcatct ggcgcatgaa aggtcgtcca gaatttatga aacttttggc tagcgtcgat
   129241 gtgcacgcac cagccaaact ccgtgtcaat gtgcaagtac caaacttcga cgatttcttt
   129301 acaacctatg atgtcaaaga aggagacgga atgtggcgtt caccagagga gcgcgtgatt
   129361 atttggtaat acaaaaaatc tagtcatcag aaaaaaggca tccaatcacg tgtgaaaacc
   129421 ttgataggat gccttttgta atagaaagat ttgctggata gtttacttaa atttcgattg
   129481 tcatcatctt gctagaaaaa gggattgaag gccttttcgt gagcgatagt agtagctgga
   129541 ccatgtcctg gatagacatc gtagtttggt agggtgaaga gttgggtctg gatactatga
   129601 aggagttgct ccatgctacc agtcggaagg tcggtccgtc cgatagtttc gcggaataga
   129661 gcatctcccg tcaagactag gtgagcatca ggaaagacta gggaaacacc accgatagag
   129721 tgccctgggg tcggtagaac cttaaaacga aattcctcta gttggtattc ttcgtgaaag
   129781 acaaaggtgt gttctgcagg ttttgtgacc acatctgcca tatcatcgtg gcgagggaga
   129841 ccggagagat tatcgacagg agtgtagagc cagctggctt cgctctctgc gatatagaca
   129901 ggaggattgc caaacgtctc gcgaaccaag tccagactca tgatatggtc ataatgggcg
   129961 tgggtcaaga gaatagcaca gatcggtttg ttgatcttct cgattgtctg acgaatggct
   130021 tcccaatgac taccaggatc gacgacgatg aggtgctttt cgccttctag ataataggta
   130081 ttttcatagg caacaggatt cacggtttta tggattttca tactagctcc aatctcaaag
   130141 aatgtactaa tactcttcga aaatctcttc aaaccgcgtc aactttatct gcaacctcaa
   130201 agcagtgctt tgaacagcct gcggctagct ttctagtttg ctctttgatt ttcattgagt
   130261 ataaattaag tatagcacag ttagggagaa taggtaagga tttaaaatga acttaaaaac
   130321 cagcatgact agatgaagac aggctggtta tcaatttatc aatattggaa aggtgtcaat
   130381 tgcccttcat aggttgcata aactccgtca ttagcttgtt tgatagacgt gatgtttaga
   130441 gtgctaccgt agttggcttc tcatttgtcg ctatattcac tataagttat cctactgggc
   130501 aggttctggt cgttagcata gtattgaacg actgtttttt atagttttgc tggctgaata
   130561 ggaacaggca gcaaactcct aacattagga gagcaaagat agaaatagca gtttttttca
   130621 taggtattct ccttataaac taaaggatag aagaaagtat cttgaggatt tttatactct
   130681 tcaaaaatct cttcaaaccg cgtcaacgtc gccttgccgt atatatgtga ctgactttgt
   130741 cagtcttatc tacaacctca aagcagtgct ttgaacagcc tgcggctagt ttcctagttt
   130801 gctcttggat tttcattgag tattaattcc aaaatccagt caaggtacca gtgtatgtga
   130861 tacgagttcc accgtttatc tttcgtatct tcaatggaat tggggaaatc agaaagtctt
   130921 tgggttacaa tatggtttcc gttcttctat ctctccttct atcacctaag tttaaaatct
   130981 aacttcgtag tatattatgg gccaataatt cagaattatc aagcaatttt gaattatttt
   131041 tttcttattc tgttccaatc tagttttcat attcttaaaa aagtgataaa atggtaggaa
   131101 gaattggaga gtagagatgc cgaaagaagt gaatttaaca ggcgaagaag ttgtcgcttt
   131161 aaccaaagaa tatttaacgg aagaggatgt tcattttgtc cataaggcct tggtctatgc
   131221 tgttgaatgc cacagtggtc aatatcgcaa atcaggcgag ccttatatca ttcaccctat
   131281 ccaagtggca ggtattttag ctaagctaaa gctggatgct gtaacagtag cttgtggatt
   131341 cttgcatgat gtggtggaag atacagatgc gaccttggac gatttggaaa gagagtttgg
   131401 tcctgatgtg cgggtgattg ttgacggagt taccaagctt ggcaaggtcg agtacaaatc
   131461 gatcgaggag caattagcgg aaaatcatcg caagatgctc atggccatgt ctgaggacat
   131521 ccgcgttatt ttggtcaaac tgtctgaccg cttgcacaat atgcggaccc tgaaacatct
   131581 tcgaaaagac aagcaggagc gtatttccaa agaaaccatg gaaatctatg ccccacttgc
   131641 ccatcgtttg gggatttcca gtgtcaaatg ggaattagaa gacttgtctt tccgttatct
   131701 caatccaacg gagttttaca agattaccca tatgatgaag gaaaagcgca gggagcgtga
   131761 ggccttggtg gatgaggtag tcacaaaatt agaggagtat acgacagaac gtcacttgaa
   131821 agggaagatt tatggtcgtc ccaagcatat ttactcaatt ttccgcaaaa tgcaggacaa
   131881 gagaaaacgg tttgaggaaa tctatgatct gattgctatt cgttgtattt tagataccca
   131941 aagtgatgtt tatgccatgc ttggttacgt gcatgaattt tggaaaccga tgccaggtcg
   132001 cttcaaagac tatattgcca accgcaaggc caatggttat cagtctatcc atacgactgt
   132061 ttatggacca aaagggccga ttgaattcca gattcgaacc aaggaaatgc acgaggtggc
   132121 tgagtacggg gttgcggctc actgggctta taagaaaggt ataaaggggc aagttaacag
   132181 caaggaatca gctattggaa tgaactggat caaggagatg atggagctcc aagaccaggc
   132241 tgatgatgct aaggaatttg tggactctgt taaggaaaac tatttggctg aggagattta
   132301 cgtttttacc ccagatggag ctgtccgttc ccttcccaaa gattcaggac cgattgattt
   132361 tgcctacgaa atccatacca aggtcggtga aaaagcaact ggtgccaagg tcaatggccg
   132421 catggttcca ctgacaacca agttaaagac aggggatcag gttgaaatta tcgccaaccc
   132481 gaactccttt ggacctagcc gtgactggct caatatggtc aagactagca aggcgcgcaa
   132541 taagattcgc cagttcttta aaaaccaaga taaggaattg tctgtcaaca agggtcgtga
   132601 gatgctgatg gatcagttcc aagaaaatgg ctatgtggca aataaattta tggacaagcg
   132661 ccacatggat caagttctgc aaaagaccag ttacaagaca gaagactccc tctttgcggc
   132721 cattggtttt ggggaaatcg gtgcgattac cgtctttaac cgtctgactg aaaaggagcg
   132781 ccgtgaggaa gagcgtgcca aggccaaggc tgaggcagag gagcttgtca aaggtggcga
   132841 ggtcaaggtt gaaaataaag aaactctcaa ggtcaagcat gaggggggag tggttattga
   132901 aggtgcttct ggtctcctag tgcggattgc taagtgttgt aaccccgtgc ctggtgacga
   132961 tattgttggc tacattacca agggtcgtgg tgtggctatt caccgtgtgg actgtatgaa
   133021 cctgcgtgcc caagaaaact acgagcaacg tctccttgat gtggaatggg aagaccagta
   133081 ctctagctca aataaggagt atatggccca tatcgatatc tacggtctca accgtacagg
   133141 actgttgaac gatgtactgc aagttctttc aaatacaacc aagaatattt caacggtcaa
   133201 tgcccaacca accaaggata tgaagtttgc taatatccat gtgtccttcg gtattgccaa
   133261 cctctctaca ctgactacgg ttgtcgataa aattaagagt gtgccagaag tttactctgt
   133321 caaacggacc aacggctagt tgtcctagct cttactagaa aggctattat gaaaatcatt
   133381 atccaacggg ttaaaaaagc ccaagtgagt atagaaggcc agattcaggg aaaaatcaat
   133441 cagggacttt tattgctggt tggtgttgga ccagaggacc aagaggaaga tttggactat
   133501 gctgtgagaa aactggtcaa tatgcgaatt ttttcagacg cagaaggcaa gatgaaccta
   133561 tctgtcaaag atattgaagg agaaatcctc tctatttctc agtttaccct ctttgcggat
   133621 actaagaaag gcaatcgtcc agcctttaca ggggtagcta aacctgatat ggcatcagac
   133681 ttctatgatg ctttcaatca aaaattagcg caagaagtgc ccgttcagac aggtatcttt
   133741 ggagcaaata tgcaggttga gctggttaat aacggacctg ttaccattat cctagatact
   133801 aaaaagagat aagaaagacc aagcccagtc ggcttggtct ttctcatcta tcataaaata
   133861 ctccaaaaag aaatcggttc ttgatatgct tgggggaagt ctcttttcag gctttggcag
   133921 atgcgatagg aagggatgag atgtcctagg atgaggagag ttccctgaag gaaaagtgga
   133981 atatcactta aagacaccaa ggagagaatc atcaggctat cccataggag aatttgtaaa
   134041 gcaaaacgcc agaatctcgg tctaatctgg gaatagagtt gactaaagtg gtcacaaagt
   134101 tggtttgaaa gataggtcaa tagcacagga tgaaagaaaa tgagccaacc gctataaatc
   134161 aaaatccagt cccaagtaag cccccctttt taaatgtcaa aaatgccagc atgattccat
   134221 caatgacaag gagttgaatg gttttgatga agatgatttt tttcatgcta aaacctcctt
   134281 ttccttagag acactcccct acaggtattt tagaatgtat attgcttaga tattccttat
   134341 tttattagct ttttaaggta ttaaagtagt tatataagtt tatgaagggt atcctatcct
   134401 gcacggctaa ttttgagttc gaaactgagg agtttataac tcaaaatttc gattaaatca
   134461 gcatttaacg atagtatgtt tgtcataaaa tgataaattt ttagattgtg gaaatttttt
   134521 tttaacttaa ttcttgattt tttttctaaa tgtgatatac ttaatttacg ggataaaaaa
   134581 accaccttag aaaggtgtga taatgtgcaa aaagagaatg ttagaatgcg tttagcgtct
   134641 gaatccagac agatattaga taagcttaaa gatgatgttt acaataaatt aggctatgaa
   134701 gtaagctatt ccagtattgt tagtcaagct gttagagaat acgttcctaa aaaagaacgt
   134761 atagattgga taaaattaaa agagacagct ataccctttt catcgttaaa acagagcaat
   134821 aattgggagt accagacatc acttatgtta gaggaagatg tattaatctt actgtctgaa
   134881 ctacaaaatt ttttcttaga tgtcttccaa gcgaaacgta tacatagggc attttgtgta
   134941 cgcctatgct tgaaagcaca atttttatta agtaataatg attcttaata ctatcaatat
   135001 taatgcggag tgtaatgctc cgctaaaata aaacctatta cgggataaaa acactacttt
   135061 atttaggatg gaaagaggaa cgaatgaaga tgaaagctag agattcacca ttgaattgat
   135121 tttgttttta gaaaaaatca ataattagaa aaaatacgag gtaaaaaaat gaatagagat
   135181 gtattagagt ttctgagaac agagaccgct gaaaaaatta gtctttatat aagcgaggct
   135241 aatagattgg agggcgatgt aactctactc gcacctagtt ctcaagattt ggaagatatt
   135301 aaaaatgcta tgctttccaa ttctaatctc ggattaaaag ttgcgagact ggatgtgatg
   135361 aagaaaatag catatgcttc tacaagaaat cattatttaa caggggctac gatttttggg
   135421 gatatttcga aaggaacata caattgtgat cctaaaagtt atgtctaata taagggaggt
   135481 taatccctcc ccttgttttt gaaaatcgaa aggaaaagta taaaaatgaa agttaatgaa
   135541 tatttctgga gaacgagctg tcttatacta aaaaagaaga aatcgataaa atagtatacg
   135601 tgttagagat gtgtttgtcg taaaagtctg gatagttttc tcctaggtag tcagctgtca
   135661 tataataaaa agtagaatgg caagcagtga taattggcat aagagatgaa aaacgctgag
   135721 aactaatgaa ggctaagaga acaaaaaata gaaaatcaat ggtgagaacc cctaaatagt
   135781 agaagcgaat ctttttattg atttgaggat aaatctcagc gaattgatgt ttgagtcgga
   135841 cgaccaagag aaatagcagg agtccttgag caaggaagaa aattaaacca gagagcaaga
   135901 gccactcaaa agatgtctcg agtctagtga taaaaaatgc aaatagtagc aaatcaataa
   135961 ctgcaattgc tataaaatgg attctataga gttttttcat gacaagacct tcctctttta
   136021 tctaacttca ttctactcca aaagaatggg agttacaact aaaatgataa aaatagcaga
   136081 agggagattc tcttaagttg gctagtattc tttatttgag tttccttcta tgtatctaac
   136141 ttcttcatca ttccagacaa ataaagctcc gattgcattg aggatataaa agatgtattt
   136201 accgatattg gcgaagtttc cttgaatacc agcttttgtc agctgaacga aattgtaaat
   136261 caaccaaaag ccccactgag ttgttagttt caatgcattc aaagcattgg caatgaggga
   136321 cagtgcaaag gcaatagttg ttacgtaggc aaggagattc atcttgccct catatccgat
   136381 atagttggtc acaaaggcaa agaggaaggc gatgatggaa atgatgatgg ccgccaattt
   136441 tacctgtttt tggctcattt ggttgggtct gccttcttgc gaagctttcc atttctttat
   136501 agcaaaggta taaatgagga aggtgacggg ataggtaatg atggccgcct tatttccaag
   136561 gatataatca atagcaccgg acaaaatggt attaacaata ccaaagtaat ttccccattt
   136621 gcttaatttc cccgtgaaac gagtggacaa catggaaatc ccaacgttgg ttacggaaat
   136681 caatccaaag ggtacaagag ctgtccatgg tccccagtct acaaatttat cgaggcgtga
   136741 gttgaggtaa ccagatgcaa tcgcaatcca acgaccaaag caaccccgaa gaggtcaaac
   136801 tatttagatg tagcaaaaat ttttagtgat tttttcatag gttaaactac ctttcttttt
   136861 ttcaaatatt ctcccaccaa atgaaagtaa aataaaatga tagaaataaa accctgaaaa
   136921 taaaactttc agggttggta ggggacttga gaaattagtt gattttctcg acatagagtt
   136981 gttttgcaat gtccatattc acttgtaaat cctcgtcgtt actgaggata gtgaaggtat
   137041 tgctgaagcc atcaaactgc ttgacttgga gctggtcacc gatgtgaagt gagtgcttgt
   137101 ccagataatg gagaatgtca aaactatcgt gcacccgagt caggcggtag gcgccagctt
   137161 ccttgatatc agctagtggg aggttattga tttcaacgag gagttctccc ttggcaggaa
   137221 tagttcctcc gtgggggcag gttttaggga aacctagcag tttatctagt ctttccacga
   137281 acaggtcaga gacagtgtgt tccaagacct cagcttcctc gtgaatctgg tcacttgtat
   137341 agtctaaatg atgaactaga aaaacttcaa tcaagcggtg cttacgatag agctcagaga
   137401 ccagtttgag accgaggtca gtcagtagat agccacattc cttgtccttt aggatgagat
   137461 tttcactttt cattcgtttg atcatttcag ttacggcagg gggagagact tgcatgcgag
   137521 ccgcaatttc cttgttggta atcttatgca ggtctatgcc aatttcataa atacatttta
   137581 gatagtcttc tttgtttggg gtcattcgtt tcctcttgtc taatatcttt atctagtata
   137641 tcaaaaaaag ctagatttct ctagctgtga ctttttatgt tatacttatt gcaagagaaa
   137701 aaacgaggag atggatatga cgaaaatagc tcttctttca gatattcatg gaaataccac
   137761 cgccttggag gctgttttgg cagatgctca gcagctagga gtggatgaat actggctttt
   137821 gggagatatt ctcatgccag ggacaggacg tagaaggatt ttggacttgt tggatcaact
   137881 accgattacg gctagagttt tgggaaactg ggaagacagt ctttggcatg gtgtccgtaa
   137941 ggaattggat agtactcgcc ctagtcaacg ctatctcttg cgccagtgcc agtatgtttt
   138001 agaggaaatt tccctagaag aaattgaagt gctccacaat caacctcttc aaattcatcg
   138061 tcagtttggg gatttgacag tgggaattag ccatcatctg cctgataaga actgggggcg
   138121 agagttgatt catactggca aacaagagaa ttttgaccgc ttggtgactc atcctccctg
   138181 tgatattgct gtttatggac atattcacca gcagttgctt cgtcacggga ctggtgggca
   138241 attgattgtc aatccgggtt cgattggcca acctttcttt ttggacgctc agctacggaa
   138301 ggacttgcgg gcccagtata tgattttgga gtttgatggc aagggcctgg tagatatgga
   138361 cttccgacgg gtagactacg atgtggcagc tgaattgcag ctggctaaag acctgagact
   138421 tccctatttt gaggtttact atgaaagtct ggtcaatggg atccaccata ctcatcatca
   138481 ggaatttttg agagaattgg ctcagaaaga gggttgcgat cgggagttag acgactggtt
   138541 gaaaagtggt aacgattgac attacaacta aaaagggtat aataatagaa aaagaagagt
   138601 agaggcaggg tagcctcgta aaaaggagaa gaggatgcaa attccaagta gatttaccat
   138661 tgcgactcat atgctgataa tcattgccct cgaggggaag gaaagcaagg tgaccagtga
   138721 ttttctggct gctagtgtcg gggtcaatcc tgtcattatc agaaagatct tgtcccagtt
   138781 gaagaaggca gagctgattt cagtagcgcg tggaacgggc ggaacagaga ttgtcaagga
   138841 ccttaaggat attagtcttt tagatgttta tcaggcggtc gaatgtcttg gtaagacagg
   138901 tcaactcttc agtttccatg acaatccgaa tccaaattgc cctgtaggag ctcatattca
   138961 tgatgttttg gatcaaaaat tggagagaat tcagttgact atggaggcag aacttggtca
   139021 gaccagtcta gaaaaagtcg tggccgatgc agagagtcag atgaaggatt aagagggata
   139081 aatgccctct ttttttcttt ggataattat gataaaatgt agctattaaa ggagtaagaa
   139141 atgtatctcg ttatagaaat tgtattagcc tttatagtgt cattttggaa ggataataga
   139201 agtttgtgga atccagtatt atttttatta tccctcattt caagttattt ttatctatcc
   139261 tacctttttt ataaaaatgg atacgagaat gttcagttag ctttttatgt atttaccttt
   139321 gtcttacttc cttttttgct ttttctaagt ggcatctttt taatctataa tggggtcatt
   139381 ttgttgaaac gagagggacg ttccaagccc cattatctct caatgctctt tgatttttat
   139441 tgactattag attctattta aaaagactta gaatgcacat gaaagtatgt attctaggtc
   139501 ttttgttttg tatacattta attttcaaga gtattatcta tttttccatg catggtaacg
   139561 agtatcaatc aataactggg taaggcgacc caaggtttct ctttcttctg gagtgaggga
   139621 ttgagcttgg acaaagagat gatgaatgta ttcaagcgcc tttaaggaag ccaagtcatt
   139681 gatagagcta ataccagcat caagaatagt gccaaagaag aggtcgaagt agagctgaag
   139741 ttcttcgtca gggactgtgg ccacccattc tttaaaggtt gtgtctactt gccggctatc
   139801 actgttggtc ttatccagtt gaacgaagtg cttgtcctca atctgccaac taaaggtatc
   139861 gtgctgggcg atgccaccca gggcagtact ctgaacgatg atttggtgag caggaatttc
   139921 cagcatcata ccgataatag acccttgtgg aatgaatatc ttgcttctat ccattatcct
   139981 ttgataaccc gcagtctgtg tcaattcttg atggagacca ggtgcatcaa atgtataaac
   140041 tgctgtgatc tgattttgca aactttgctc aatttggcta gcagcataga tagcgagatt
   140101 tcctcccttg gaatgcccag ccagaataac cttttgctta ggatgatggg caaaaaagtt
   140161 ctttaaatag cgaagggcgt gcttttgagc aggaatttcc ttcatatagg tcaggtggaa
   140221 atcttccttc cagccaatga tactgtcatc tgtcccacga aagacaatca gataggtatc
   140281 gaggctgaca cgataagtca tagccgcaaa ttgcttttgc agttcagggt cgatgtcgtt
   140341 gataaaatgg gagagtttgc aatttttgaa gcgcttgtgt tgagccaatt catctaataa
   140401 ttgaaggcga tttttgctag taagcatggt gggctctctt ggaacctgag gtgctagatc
   140461 taaaagacgt tgaggaagtg tggagaccag attatcaaag gagaggtagg tgatttctat
   140521 taaggttaga atgtctaact cattcaaggg aaggtcgtaa taagaatcat atgcgacatc
   140581 tttcagatag tcaaaaatat tggccataag agctcctttc tttttattta tcttagcaaa
   140641 tttccctcaa attagctagt agcatagcct gtttgtactg gctaaaaaca ggctatttca
   140701 aattcagttt cagaccatct agcatggaaa aatctgttat aataatggaa aaggagaagc
   140761 gcatgcacaa gattttatta atagaagatg atcaggtcat tcgtcaacag attgggaaaa
   140821 tgctctctga atggggattt gaagtggtcc tggtagaaga ctttatggaa gttttgagtc
   140881 tatttgttca gtcggaacct catctggtcc tcatggatat tggtttgccc ttgtttaatg
   140941 gttatcactg gtgtcaggaa atccgcaaga tttccaaggt acctatcatg tttctttctt
   141001 cgagagacca ggctatggat attgtcatgg caatcaatat gggggcggat gactttgtga
   141061 ccaagccttt tgaccagcag gttcttttag ctaaggttca gggcttgttg cgtcgttcct
   141121 atgagtttgg gcgtgatgag agtttgctgg aatatgctgg tgttatcctc aataccaaat
   141181 ccatggattt acattatcaa gggcaagtct tgaatttgac caagaatgaa ttccagattt
   141241 tacgcgtgtt atttgagcat gcaggcaaca tcgtagcacg tgacgacctg atgcgggaac
   141301 tttggaacag tgactttttc attgatgata ataccctctc tgtcaatgtg gctcgtttgc
   141361 gtaaaaagtt ggaggagcag ggattggtag gatttatcga gaccaagaaa ggaatagggt
   141421 acggattgaa gcatgcttga ttggaaacaa ttttttctag cctatctgcg ctcccgtagt
   141481 cgtcttttta tctatctgct ttttttggca tttcttgtct tactctttca gtttttattt
   141541 gccagtctag gaatttactt cctctacttt ttcttcttgt gttgctttgt aaccatctta
   141601 tttttcactt gggacatatt ggtggaaacg caggtctatc gccaggaact tctctatgga
   141661 gagagggaag ccaagtctcc tttggaaata gctttagcag aaaaattaga agcgcgtgag
   141721 atggaactct atcagcagag gtcaaaagca gaaagaaaac tgacggattt gctggattac
   141781 tataccttgt gggttcatca gataaagacc cccattgcag ccagtcaact cttagttgca
   141841 gaagtggtcg accgccaact gaagcagcag ctagaacagg aaattttcaa aatcgactcc
   141901 tataccaacc tagttttaca gtacctgcgt ttagaaagtt tccatgatga tttggtctta
   141961 aagcaggttc aaattgagga cttggtcaag gaaataattc gtaaatatgc tcttttcttt
   142021 attcaaaaag gcttaaatgt caatctacat gaccttgata aagaaatcgt gacggataaa
   142081 aagtggctgc tagtggttat tgagcaaatc atctcaaaca gtctcaagta caccaaggaa
   142141 ggtggtctgg agatttatat ggatgaccaa gagctttgta tcaaagatac gggaatcggg
   142201 ataaaaaaca gtgatgtcct ccgagtattt gaacgtggct tttcaggata caatggccgt
   142261 ttgacccagc agtcctctgg acttggcctt tatctatcta agaaaatttc tgaagaactg
   142321 gggcaccaga ttcgtatcga gtctgaggtc ggaaaaggaa cgacagtgcg gattcagttt
   142381 gctcaagtga acttagtcct tgagtaaaaa tagatgagaa aaagcctcca gattggaggc
   142441 ttttatgcta gactcttatt tctcaacgcg tgatttgttg gcgatatcag ctaggatagc
   142501 ttgaacaaaa ttatcaactg agacagtttg tgtttctttt tggccgtagc gacgaacgtt
   142561 gactgtttcg tcttccattt ctttgtctcc aacaattaat tggtaaggaa tcttgctggt
   142621 ttgtgaagca cggatcttga actgcatttt ttcattgcgc tcatctacgt ctgcacggac
   142681 accgcggtca cggagtttct tggccacttc ccaagcgtag ttcacgtgtt tttcgttaga
   142741 tactgggatg agggttactt ggtgtggtgc cagccatgtt gggaaggccc ccttgtagtt
   142801 ctcaatcaag atagctgtga agcgttccat agttgagata accccacggt ggatcatgac
   142861 tggacggtga tcttcgccat cagctccgat gtatttgagg tcgaagcgtt ctggcaacaa
   142921 gaaatcaagt tggatagtag aaagggtttc ttcttttcca agggcagttt taatctggat
   142981 atccaatttt ggtccgtaga aggctgcttc accttcggct tcaaagtagt ccacgcccat
   143041 ttcatcaaga gctgcacgaa gcatggtttg ggcattttcc cacatctcat cgttatcaaa
   143101 gtacttatga gtatcttgag ggtcacgaag agagaggcgg aagcggtagt cagtcaagtt
   143161 gaagtcttca taaacatcga taatcaactg aagggcacgt tggaattctt cttggatttg
   143221 ttctggagta acgaataggt gaccgtcgtt gagtgacatt tcacgtacac gttgaaggcc
   143281 agtgagggca ccagattttt cgtaacggtg catcataccg atttcagcga tacggattgg
   143341 caattcacgg taagagtgaa catggtgttt gaaaacttgg atgtggtgcg gacagttcat
   143401 tggacgaagg acaaattctt ccccgtcacc catgtccatg gttgggaaca tgtcttcttg
   143461 gtaatgatcc cagtgaccag aagtcttgta aagctcaaca gaagcaagtg gtggagtgta
   143521 gacgtgttgg tagccagaag ccaactcttt gtttacgatg tagcgttcca attcacgacg
   143581 gatagtcgca ccatttggca accagaatgg caaaccttgt cccacttctt gtgaaatcat
   143641 aaagaggtca agctctttac caagtttacg gtggtcacgt tccttagctt cttcacgcat
   143701 ttgaaggtag tttttcaagt ctttcttgtc aaaccaagct gtaccgtaga tacgttgcat
   143761 catagcgttg tcgctgtttc cacgccagta agcaccagct acatggagaa ggtggaagat
   143821 ttggatacga cctgttgatg gaacgtgagg tccacggcag aggtctacat attcaccctg
   143881 acgatagata gtcaaaccgc cttcgtcttc tgagtgttct tcaatcaatt ccaacttgta
   143941 agggtcattt ttgaagattt cacgtgcctc gtctttagtc acttcttcac gaatagatgg
   144001 gaagttttct ttgacgattt tttgcatttc ttcttcgata cgaggaaggt cttcgttaga
   144061 gatttgacca gctatgttgt cagtatcgta gtagaaacca tcttcgatgg ctggaccaac
   144121 tcccaagtga atgtctggga aaagacgacg agctgcttgg gcgaacaagt gagctgctga
   144181 gtgacgcaag attggaaggg catcttcgtg atcaggtgtc acaatttcga tgcttccatc
   144241 ttcagtgata gcgcgagtag tgtcgatgag tttgccgttg aatttaccag ccaaggcttt
   144301 tttagctagg gaattgctga tagattgggc aatttcaaaa gttgttacgc cagattcgaa
   144361 ttcacgaaca gcgccatctg ggaaagtaat gttaatcatg atgttctcct tttttattat
   144421 ttcatagttt ctaagcattg attttttatc agcagactac ttccaagtcc taacgttcaa
   144481 ttgcttttct ttatcagaga ggaagttttc catttccgtc agaatgtcta tatccaaacg
   144541 ttgagaaagt tctaatagcc accagatatt ttctgaaagt ttttgttcca gtgtgtaggg
   144601 tgtttcatca tagtagcgtc cttgctttgt catcaccaat cgttggaaat ttccaatatc
   144661 attagataaa gccaagaggt cttcttctac cgtccacttg gaatcatgat gcttaacttc
   144721 cagttcgtga taagcttgtc ggattgccca actgtgctcc actaattctt gcaactccat
   144781 aattagtatc ctaataaaaa aatgcgacat cctcgaaagg acgtcgcaac gtggttccac
   144841 cttcatttat gtacctcaaa agagagggac acctctgatc ggctctaacg tggccaccgt
   144901 tttatgtttt cataaaaaac tcaagagtag tatcagttta gacttcctat gcgtttccag
   144961 caaccacgca ctctctagta gaaagggact aagtgacttg tctctatgga ttattatagc
   145021 atgattgtga gatttttcaa ggattttgtg aaagtttttt gtttttcatt ttttgtagaa
   145081 tatgcttgat gctaatacca gaatccatgc ccaccagagc aactgtttca tagattagca
   145141 agtaaattag tataaactca ccaaagatta tgatagtgaa gtaaaagagc agtccgttac
   145201 caactaacca tcaaagtgag aaacggaaac ggtagctata gagtaacgat acaatcaaga
   145261 ttaccagagg tgtaaagaag agaagattgt ttatatagag tcccttgagt gtaagggggt
   145321 cagaaacaac tagcaagaac aactcataaa gtggccaata aatatgacca gatagtaggg
   145381 gagatgggaa tagaatctac gcatgataat cacctcgttt taaaaaaaac agacaactta
   145441 gatctcttgc tatgattatt ataagcatgt ttaaaacaag aaagtaaatt tgttgacaaa
   145501 gaagattttt cttttcacta gaatcatagt tagttttctt ggtagaaata ttttgataat
   145561 aattaagcaa gactattgac attgattatt aagagtgtca caattgctgt aactaaaata
   145621 attacaacaa gagaggtata aaaaatgaaa ctagcagtta ttgcagcaaa tggacaagtg
   145681 gggaaagcaa ttgttgaaga agcagtcaaa cgaggacatg aagtaacggc tattgttcgt
   145741 tctgaaaaca aaagtcaagc tgagtctatt attaaaaaag atttatttga gttgacaaaa
   145801 gatgatctta ctggatttga tgctgttatt tcagcgtttg gtgcttatac accagatacg
   145861 ctaccgctcc atagcaaatc aatcgaacta tttaatcagc ttcttgctgg aacacagaca
   145921 cgttttctag ttgtaggggg agcagaaagt ctttatatag atgaaacaaa aacgacacga
   145981 cttttagata cgtctgattt tcctgaagaa tttaagtcac tagcaaaagc tcaagcggat
   146041 gaattggatc ttcttcgtac aaaaaataat ctcaactgga cttttgtcag tcctgctgta
   146101 gattttattc ccgatggtga aaaaacagga aactacattc tagcaggaga aatttttact
   146161 actaatgaaa aaaggaataa gccagattag ttatgcagat tatgctattg gattggtaga
   146221 tgaacttgaa aaaggtcatc atataaaaga acgtatctct ttacttgaaa aataataact
   146281 atgagagtat taatgtttga cagaaaattt aaatcttggt aaaataggga ttgtcgtaaa
   146341 gacaaataac ttcttcttgg ttacaggcat gccaacctgt cactcggatg aagccaaata
   146401 aaaaggagaa acatcatggc aatctcaaaa gagaaaaaaa atgaaatcat tgcacaatat
   146461 gcacgtcacg aaggtgatac aggttcagta gaggttcaag ttgctgtcct tacttgggaa
   146521 atcaaccacc ttaacgaaca catcaaacaa cacaaaaaag accacgctac ttaccgtgga
   146581 ttgatgaaaa aaatcggtcg tcgtcgtaac ttgcttgcat acttgcgtaa aaacgacgtt
   146641 aaccgttacc gtgagttgat caactctcta ggacttcgtc gctaattcaa gatacaaagg
   146701 ccgtcaaaag cacaaagcaa aaataggaaa attgacgaag aaacttcagt ttctaggaga
   146761 ttttatcttt tttgccaagt gcttaggccg tgttcaattg agcatatctt gataataaag
   146821 ctactctaaa ttgggtagct tttttgcgtt gtcaccttac ctcgctatac tcaagtataa
   146881 tctttggtta cggttcctag cactgtaagg taaaataaac cagcttttct cccttcgggg
   146941 agattttttt tgtttcactg aaagtttcgt acgatcttcg cctcgtcgcc tagtctataa
   147001 acgatttatc tagcaagaat catgatgcta agggcgtcaa aaatccgtat gaaaataggg
   147061 aaatgacaca gtgttcgatg agcacaagga gtttcatctt tttcactagg attttagccc
   147121 gggctaaaat cagctctctg acttcagagg gcttttttat tgaggtttta tcggtaacaa
   147181 ttttggagac tacaaaaacc tcaaatggta tcagctaatt acaccataaa ggtgcgcagt
   147241 tactcggctt ttcaagccga gtagctgtat gcaagccccc tagaagagcc cactctttac
   147301 aaagtaaagt atagtatgtt atactttaca tggaagtagt cactgaattc cagttagaaa
   147361 ttactttgta actacgtttt gaggaggagt aaaatgcttt cctacgttcg acattaccca
   147421 ctagcgatag ctaaattaat gtgtctgtgc tctcctgaaa tctgctgatt tattactgac
   147481 taatacagga ggtttttttt atgggacaga caatcatatc tgctattggt gtttatattt
   147541 ccaccagtat cgattattta attattttaa ttattttatt tgcacagcta tcacagaata
   147601 aacagaaatg gcatatttat gcggggcaat atctaggcac aggcttactt gtaggggcga
   147661 gtttagttgc tgcttatgtc gttaatttcg tgcctgaaga atggatggtt ggattgcttg
   147721 gtttaatccc tatctattta gggattcgct ttgcaattgt tggagaagat gcggaagaag
   147781 aagaggaaga aattattgaa agattagaac aaagcaaggc aaatcaactg ttttggacag
   147841 ttacattgct gacaattgcg tctggcggag ataatttagg tatctatata ccttattttg
   147901 cttcgttaga ttggtcacag accctcgtgg ccttgcttgt gtttgtaatc ggcataatta
   147961 tcttttgcga gattagtcgg gtgttatcct ctattccgtt aatattcgag acaattgaaa
   148021 aatacgagcg aatcattgtg cccttagtat tcattctact tggactatac atcatgtatg
   148081 aaaatggcac gatagagact tttctgatcg tgtagatttt tttgtttcac taggatttta
   148141 gcccgagctc aaatcagctc tctgattttc agagggcttt ttcattgagt ataaatggac
   148201 aatcttaaag ttactctatt gtagagtggc ttttgatttg attaggagat tcttataaat
   148261 atagtaaaat gaaacaaaaa caggacaaat cgatcaggac agtcaaatcg atttctaaaa
   148321 atgttttaag aagtagaggt gtactattct agtttcaatt tgctatataa atgaaaacct
   148381 tagctgtttg gccaaggttc atttcttcta tgcaagttct tctcttttct tatctgggtt
   148441 ccagatgaag cttgcgataa agctaaagat gatggttagg atagcgagga taatagcaag
   148501 gatgagggca gggatgcgga taaaccacca gagtggattt ggttttttat cattgtgcca
   148561 ttgtttcgtt tcttcgtcca gacgttggaa ttctgtttga atacgattgg cgactgtttc
   148621 aatgccttca tcattcattt tcttgatatc tgagatatcg attggatttc caaagttcat
   148681 atcgacacgt tcacggctaa tcaagccctt caaaatcatg ggaccggtgt aggtaaccgg
   148741 catgatacgg accttggcca ttttggcaat cagtgctgcg ccccccttga catcgtttga
   148801 gtggcggcta ccacttggaa acatgatgag agagcggtca ctttttttga gaacgttgat
   148861 aggatatttg atggctgagg cgctgggatt ttcacggtcg atgggaaagg cgccacacat
   148921 acgaatccac caaccaaaga tacggttggt aaagagttct ttttttgcca taaagatgaa
   148981 ctgttttggc ttggtcgcaa aggccatata aacaggatcc caccaggtac ggtgaggcgc
   149041 aactaaaata taattttcat cttgattagg aattttatca gtattatgat agtgagcatt
   149101 gccattgatg gaccataaga gcaacacaac taatccacgc aaataagtat aaaacatgcg
   149161 atctccttcg attgttttct tgttattatt ataccttatc aaaggagggc tggcaaactt
   149221 ttcccttgac tagatgcata tttgggatga aattagaatt ctgttaaaaa aaatggtata
   149281 atagaattta tggataaaaa taagattatg ggattaaccc aaagagaagt caaggaaaga
   149341 caggctgagg gtttggtcaa tgactttacc gcatcagcca gtaccagcac ttggcaaatc
   149401 gttaaacgaa atgtctttac cctttttaac gctttgaact ttgccattgc tttggccctt
   149461 gcctttgtgc aggcttggag caatctggtc ttctttgctg ttatctgctt taacgctttt
   149521 tctgggattg tgaccgagct acgagccaaa cacatggtgg acaagctcaa tctcatgacc
   149581 aaggaaaagg tcaaaaccat ccgtgatggt caggaagttg ctcttaatcc tgaagaatta
   149641 gtgctaggag atgtcattcg tttgtctgca ggagagcaga ttcctagtga tgccttggtt
   149701 ttggaaggct ttgcggaagt caatgaagcc atgttaacgg gagaaagtga tttggtgcaa
   149761 aaggaagttg acggcttact tttgtcagga agtttcctag ccagtgggtc agttttatct
   149821 caagttcacc atgtcggtgc agacaactat gctgccaaac tcatgcttga ggctaagacc
   149881 gttaaaccca tcaactcccg tatcatgaaa tcgctggaca agttggctgg ttttactggg
   149941 aagattatca ttccctttgg tctggctctc ttgctggaag ccttgctttt aaaaggcctg
   150001 cctctcaagt catccgttgt aaactcgtcg acagctcttt tgggaatgtt gcctaaggga
   150061 attgcccttt tgaccattac ttcgctcttg actgcagtga ttaagttggg cttgaaaaag
   150121 gtcttggtgc aggagatgta ctctgttgag accttggcgc gcgtggatat gctctgtctg
   150181 gacaagacgg gcaccatcac ccaaggaaag atgcaggtgg aggctgttct tccactgacg
   150241 gaaacttacg gtgaagaggc tattgccagc atcttgacta gctacatggc ccatagtgag
   150301 gataagaatc caactgccca agccattcgc cagcgttttg tgggagatgt tgcttatcct
   150361 atgatttcca atcttccctt ctcgagcgac cgcaagtggg gggctatgga gttagaaggc
   150421 ttggggacag ttttcttagg ggcacctgag atgttgctgg attctgaagt cccagaagcc
   150481 agggaggcct tggagagagg atcacgtgtc ttggtcttag ctctcagtca ggagaaatta
   150541 gaccatcaca aaccacagaa accatctgat attcaggctc tagccttgct ggaaatcttg
   150601 gaccccattc gagagggagc agcagagacg ctggactatc tccgttctca ggaggtggga
   150661 ctcaagatta tctctggtga caatccagtt acggtgtcca gcattgccca gaaggctggt
   150721 tttgcggact atcacagcta tgtagattgc tcaaaaatca ccgatgagga attgatggcc
   150781 atggcggagg agacagctat tttcggacgt gtttcccctc atcaaaagaa actcatcatc
   150841 caaacgttga aaaaagcggg tcatacaacg gctatgacag gggacggggt taatgatatc
   150901 ttggcccttc gtgaggcgga ttgttctatc gtgatggcgg agggggatcc agcaacccgt
   150961 cagattgcca atctggttct cttgaactca gactttaatg atgttcctga gattctcttc
   151021 gagggtcgtc gcgtggtcaa taacattgcc cacatcgccc cgattttctt gataaagacc
   151081 atctattcct tcctgttagc agtcatctgt attgccagtg ctttactagg tcggtcagag
   151141 tggattttga ttttcccctt cattccgatc cagattacca tgattgacca gtttgtggaa
   151201 ggtttcccac cattcgttct gacttttgag cgaaatatca aacctgttga gccaaatttc
   151261 ctcagaaaat ccatgcttcg tgccctacca agcgctctca tggtcgtctt cagcgtcctg
   151321 tttgtgaaaa tatttgggag tagccaaggt tggtctgagt tagaaatctc aactctactc
   151381 tattatctct tggggtcaat tggtttctta tccgtattta gagcctgcat gccatttacc
   151441 ctatggcgtg tcctcttgat tgtttggtca gtaggaggtt tcctagccac agctctcttc
   151501 ccaagaattc aaaaactgct tgaaatttca accttaacag gacaaacatt acctgtttat
   151561 ggtgtcatga tgttggtctt taccgtgatt ttcatcctga ccagtcgtta ccaagcgaaa
   151621 aaataaagaa agactgcaat ctgtggattg cggttttttt aggtacaaga ttgccagccg
   151681 aaatgtggta taataagagg taatagagtt tggaaagtga gagaaaatga tttcaaagag
   151741 attagaattg gtagcttcct ttgtgtcaca gggggctatt ttactagatg tgggaagtga
   151801 ccatgcttat ctgcctatcg agttggttga gagaggccaa atcaaaagcg ctattgcagg
   151861 tgaggtggtg gaaggtccct atcagtctgc ggttaaaaat gttgaggctc acggcctaaa
   151921 ggagaaaatc caagtccgtt tagccaatgg cttggcagct tttgaagaga ctgaccaagt
   151981 gtctgtcatt accattgctg gcatgggtgg tcgtttgatt gctaggattt tagaagaagg
   152041 tttggggaag ttagctaatg tagagcgttt gatcctccag cccaataatc gtgaagacga
   152101 cttgcgtatc tggctacagg atcatggatt ccagattgta gcagaaagca tcttagaaga
   152161 agctggaaag ttttatgaga ttttggtggt ggaagcagga caaatgaagc tatcagccag
   152221 tgatgttcgc tttggtccct tcttgtccaa agaagtcagt ccagtatttg tccaaaaatg
   152281 gcaaaaagaa gctgagaagc tagagttcgc cctcggacaa atcccagaaa aaaatctgga
   152341 agaacgtcaa gttctagtag ataagattca agctatcaag gaggtgcccc atgttagcaa
   152401 gtgaagtgat ccaagcttat gaagcctttt gccctcagga attttctatg gagggagaca
   152461 gccgtggtct gcaaattggc actttagaca agggtatcca aagggtcatg gttgccctcg
   152521 atattcgtga agagacagtg gcagaggcca ttgaaaaggg tgtggacttg attatcgtca
   152581 agcacgcgcc tatctttcgt cctatcaagg acttgcttgc cagccgtccg caaaatcaga
   152641 tttacatcga cctgattaag catgatatcg cagtttatgt cagccatacc aatattgata
   152701 tcgttgaaaa tgggctcaat gactggtttt gtcagatgct aggaatcgag gagacgactt
   152761 atctgcagga aacaggtcca gaacgtggaa ttggacgtat tgggaatatt cagcctcaga
   152821 cattttggga attggcccaa caggtcaagc aagtctttga cctagatagc cttcgaatgg
   152881 tgcattatca agagaatgat ttgcagaagc ctatttcaag agtagcaatt tgtggtggaa
   152941 gcgggcagtc tttctataag gatgctttgg caaagggggc agatgtctat atcactggtg
   153001 atatctacta ccatactgct caggatatgc tgtctgatgg cttgttagca ttggatccag
   153061 gtcactatat cgaagtgctt tttgtggaaa aaatcgcagc actccttact caatggaaag
   153121 agaaaaaagg ctgggaacta gagattttac ctagtcaagc atcgaccaat cctttccgtc
   153181 atatctagtt agaaagtgaa gacaatgaaa aaagttgcca ttattggagc aggaattgtg
   153241 ggagcaacag ctgcctacta cctctcgaga gaaagtgacc tagaggtgac cgtttttgac
   153301 catgagcaag gtcaagccac caaggccgca gcaggaatta tcagtccttg gctttcaaaa
   153361 cgccgcaata aggcctggta caagatggcg cgattggggg ctgactttta tgtggattta
   153421 ttagctgatt tagagaaatc aggacaagaa atcgactttt accagcgttc gggagtcttt
   153481 ctcttgaaaa aggatgaatc caagttggaa gaactctatc aactggctct ccagcgcaga
   153541 gaagaatctc ccttgatagg ccagttatcc attctggacc aagccccagc taatgaatta
   153601 ttccctggct tgcagggatt cgacaacttg ctctatgctt ctggtggagc gagagtagat
   153661 ggtcacctct tagtaactcg tttgctggaa gccagtcagg tcaagttggt caaagaaaaa
   153721 gtgactctga cactcttatc atcaggctac cagattggcg aagaggtgtt tgatcaggtt
   153781 attttggcaa cgggagcttg gttgggggac atgttagagc ctttaggtta tgaagtggat
   153841 gtccgtcctc aaaaaggaca actacgagat tatcagcttg cccaagacat ggaagattac
   153901 cctgttgtca tgccagaagg ggagtgggat ttgattccct ttgcaggtgg gaaattatcc
   153961 ttgggcgcta cccatgaaaa tgacatggga tttgatttga cggtagatga acccttgctc
   154021 caacaaatgg aggaggcggc cttgcctcat tacccagttt tagctagagt gacttcaagg
   154081 gctgagcgtg tgggaatccg tgcctatacc agtgatttct ctcccttctt tgggcaggtg
   154141 ccagaattgg caggtgtcta tgcagccagt ggactaggtt catcaggcct cacaactggt
   154201 cctatcattg gttaccatct agcccaactg atccaagaca aggagttgac cttggaccct
   154261 gaaaactacc caattgaaaa ctatgtcaaa cgagtaaaaa gcgaataata ctcaatgaaa
   154321 atcaaagaac aaactaggaa actagccgcg gattactcaa agcactgctt tgaggttgtg
   154381 gatagaactg acgaagtcag ctcaaaacac tgttttgagg ttgtggatag aactgacgaa
   154441 gtcagtaacc atacccatgg caaggcgacg ttgacgtggt ttgaattgga ttttcgaaga
   154501 gtataagcat tttactgaaa ttttatcagg tagtttagga tggcaaatga cattccctgt
   154561 caaaaatggt aaaataagaa aaaataatct gagaatcgag gaaaaaagat gcaagaaaag
   154621 attttggtaa ctggtggtgc cggttttatt ggaacccaca ctgttattga attgatccaa
   154681 gcaggccatc aagttgttgt ggtggataat cttgtcaata gcaatcgtaa gagtttagaa
   154741 gttgttgaaa gaatcacagg agttgagatt cctttctatg aggcagatat tcgtgacaca
   154801 gataccctca gagatatttt caagcaggaa gaaccgactg gtatcattca ctttgctggt
   154861 ttgaaggctg ttggcgaatc aacacgtatc cctcttgcct actatgacaa caatatcgct
   154921 ggaactgtca gccttttgaa agccatggaa gaaaacaact gtaaaaacat catcttcagt
   154981 tcttctgcga cagtttacgg ggatccgcac acagtgccca tcttggaaga tttcccactt
   155041 tcagtgacca acccatacgg tcgtactaag ctcatgctag aggaaatttt gactgatatt
   155101 tacaaagcag actcagaatg gaatgttgtc ttgcttcgtt actttaaccc aatcggagcc
   155161 catgagagtg gtgatttggg agaaaatcca aacggtattc caaacaatct cttgccatat
   155221 gtgactcaag tagccgttgg aaaattagag caagtgcaag tgtttggaga cgattacgat
   155281 acggaagatg gaacaggtgt tcgtgattat atccacgttg tcgatttggc taagggtcac
   155341 gttgcagctt tgaaaaaaat ccaaaaaggt tcaggactaa acgtttataa ccttggaact
   155401 ggtaaaggtt actcagttct tgaaattatc caaaacatgg aaaaagcggt gggacgtcct
   155461 attccttacc gcatcgtaga acgtcgccca ggtgatatcg ctgcctgcta ctcagaccca
   155521 gcaaaagcta aagcagaact cggttgggaa gcagaactcg acatcaccca aatgtgtgaa
   155581 gacgcatggc gttggcaaag caagcatcca aatggatttg aagactaaga tgatgatttc
   155641 aatcatcgtc ccttgtttaa acgaagagga agtacttcct cttttttatc aggctctgga
   155701 agctttactt ccagatttgg aaacagaaat cgagtatgtc tttgtcgatg atggatcaag
   155761 tgatgggacc ttggaactct taaaggccta tcgggagcaa aatccggcag tccattatat
   155821 ttctttctct cgaaattttg gcaaagaagc agccctttat gcaggcttgc aatatgcgac
   155881 aggagatttg gtggtggtga tggatgcaga cctccaagat cctcctagta tgttgtttga
   155941 gatgaaaaat gtactagaca aaaatgtaga cttggactgc gttgggacac ggagaactag
   156001 tcgggaggga gaacccttct ttcgcagttt ctgtgctgtt ctcttttatc gcctcatgca
   156061 aaaaatcagc ccagtagctc tgccgtcggg tgtccgtgat tttcgtatga tgagaaggtc
   156121 tgtagtcgat gccattttaa gcttgaccga gtccaatcgt ttttcaaagg ggctcttcgc
   156181 ctgggtgggt ttcaaaacct actatttgga ctatccaaat gtcgaaaggc aggctggcaa
   156241 gacaagttgg agttttaggc aactcttttt ctactccatt gaagggatta ttaatttttc
   156301 agattttccc ttgattatag cctttgtagc tggtctccta tcttgttttc tttctctgct
   156361 gatgaccttt tttgttgtgg ttcggaccct cattttgggc aatccgacat ctggttggac
   156421 ctctctgatg gctgttattc tctttcttgg aggcattcaa ctcttgacca ttgggattct
   156481 cggcaagtat atcagtaaga tttatttaga gactaaaaaa agaccacttt atcttatcaa
   156541 agaaaaaagt gaccttcctg attttacaga aaaaaataaa gtgaaaagac tataatttta
   156601 catggaaatg tgctaaacta gagggagtgg attatcgcca ttgatttagg cttcctggtt
   156661 tccaatcagg gcgcgagttg ggcaattttt aacagcctct aagacatcct gactaggaga
   156721 aatttctttt tccagttggt cagggtcatc gtaaaaacgc acgattccat tatcgtggta
   156781 atcaaataaa tcagaataag tttggcaaag cccacaggcg atacatcgtt caggtataag
   156841 tgtgattttc atgttcatat ttatattgta ataagaaaag taaaaaaaaa caaggagtaa
   156901 ggtatggcaa aagaaccgtg gcaagaagat atctatgatc aagaagaatc aagagcagag
   156961 cgtcggcatc gaaaccacgg aggggctgat aggatggcta atcgtatttt gacgatccta
   157021 gctagtattt tctttgtaat tgtggtggtg atggtcatcg ttctcatcta tctatcatcg
   157081 gggggaagta atcgcacagc agccttaaaa gactttcatg attctgatgc aagtgtagta
   157141 caaatctcat cttcaagcag ttctcagcct gagcagagtt cagagccaga atctacttct
   157201 agtagttcag aagaagctgc taatcctgaa ggaacgatta aagttctcgc aggagaaggg
   157261 gaagcagcta ttgccgctcg tgcaggaatc tccattgctc agttagaggc cttgaatcct
   157321 gggcacatgg ctacaggatc ttggtttgct aatccaggtg atgttataaa aataaaatag
   157381 gagccgatat gaaaacaatt caaattgcta ttgatggtcc tgcttccagc ggtaagagta
   157441 cggtcgcaaa gattattgct aaggattttg gattcaccta ccttgataca ggagctatgt
   157501 atcgtgcagc gacctatatg gctcttaaga accaattagg agttgaagaa gtcgaagccc
   157561 ttctagcctt gttggaccag catccaatca gctttggacg ttcagaaact ggagaccagc
   157621 ttgtttttgt aggagatgtg gatattaccc atcctatccg tgaaaatgaa gtgaccaatc
   157681 atgtttctgc tattgcagca attcctgaag tgcgtgagaa attggtttct ctccaacaag
   157741 aaattgccca gcaaggcggg attgtcatgg atggtcgcga tattggaact gttgtattgc
   157801 cacaagcaga attgaaaatt ttcctagtag cttctgttga tgagagagca gagcgtcgtt
   157861 acaaggaaaa tattgccaag ggaattgaaa cagaccttga aaccctaaaa aaggaaattg
   157921 ctgcgcgtga ctacaaggat agtcatcgtg agacttctcc tctcaaacaa gcagaggatg
   157981 ctgtctacct tgatacaact ggtttgaaca ttcaagaagt agttgaaaaa atcaaagcag
   158041 aagctgaaaa aagaatgtaa atgtagaaaa gccgatagat tgatatcggt tttttctaaa
   158101 tttgtcaaaa tgctgatttt agggtataat agttgctgtt cgagaaattt tgattttcaa
   158161 agaatagtga atgatgataa ggagaaatca tgaacaattt accaaattgt ccaaaatgta
   158221 actcagagta tgtctacgaa gacggtgccc tactggtttg cccagagtgt gctcatgagt
   158281 ggaatcctgc tgaagttgca gaagtagaag aaggtcttgt cgctatcgat gccaacggaa
   158341 ataaattggc tgatggtgat acagtaactc tcatcaagga cttgaaagta aaaggtgcgc
   158401 caaaagattt gaaacaaggg acgcgcgtga aaaatatcca catcgtagaa ggcgaccaca
   158461 atatcgactg taagattgat ggttttggtg ccatgaaact taaatcagag tttgtgagga
   158521 agatttaagc atgtcaaaac actataaact tgtattttat agccgtatct tcttgtttct
   158581 agcggctttt acgggagttt atcttgaaat tactaagcat ggtggttttg ggatgcttct
   158641 ctattacacg gttctgtcca acctcttggt aactattttt accctttatc ttctaaaggt
   158701 tatgagccgt gtaggtgaaa attggcaaag accaagtctc ttgcgcttaa aaggtggggt
   158761 caccatgagt atcatgatta cctgtgtgat ttaccatttc ctcttggcgc ccattgcgac
   158821 taatttctat accctagaaa atttcctttg ccactatatc gttcccatct ggtttttagc
   158881 ggataccctc ttttttgaca aacagggtca atacaagatt tgggatccag cagtgtggac
   158941 cattttaccc tttctgtata tgatgtttgc tctttttaat ggcttggttc taaaactcaa
   159001 tattccaaat gccaaggata atcctttccc ttacttcttt ttgaatgtga acaagggttg
   159061 gaatgttgtg tttaagtggt gtctgattat ctttgttgcc tatatggtag caggatttat
   159121 tttctacttt atcaagcaaa tcaagagaaa gtcatcctaa tactcttcga aaatctcttc
   159181 aaaccacgtc agtttccatc tgcaacctca aaacactgtt ttgaacaacc tgcggctagc
   159241 ttcctagttt gctctttgat tttcattgag tataagatac aagggattca ttttcgaatt
   159301 taagaaggag tctacaaacc aatgaggctt cttcttttct tgcttatttg ataactatca
   159361 aaaaagtaga agattaagag aaatatagaa agagatttca tgaaacaatt tttagaacgg
   159421 gccagcattt tggctctctc cctcgttttg attacctcct tttccatttc gagtgcccta
   159481 ccagccatgt ttgactatta tcagggttat tctaaggaac aaattgagct cttggtgagc
   159541 ttgccttcct ttggaatcat gatgatgtta ctgctaaatg gtttcttaga aaaaatattt
   159601 cctgagcgct tacagattag tttgggcttg ctgattttat cattgagcgg tacagctccc
   159661 ttctggtacc aagcctatcc ctttgtcttt ggagcacggc ttctctttgg tttgggtctt
   159721 gggatgatca atgccaaggc catttctatt atcagtgaac gctaccaagg aaaaaggcga
   159781 attcagatgt tagggctacg cgcttctgca gaggtcgttg gagcttctct cattaccttg
   159841 gccgtcggtc agttgttggc ctttggttgg acagctatct ttctagccta tagtgctgga
   159901 tttttggtgc tgccccttta tctgctcttt gtcccttatg gaaaatcaaa gaaagaagtc
   159961 aagaaaagag cgaaggaagc aagtcgttta actcgagaaa tgaaaggctt gatttttacc
   160021 ttagctatcg aagcggcagt tgtagtttgt accaatacag ctattaccat ccgtattcca
   160081 agtttgatgg tggaaagagg attgggggat gcccagttat ctagttttgt tcttagtatc
   160141 atgcagttga tcgggattgt ggctggggtg agtttttctt tcttgatttc tatctttaaa
   160201 gagaaactgc tcctctggtc tggtattacc tttggcttgg ggcaaattgt gattgccttg
   160261 tcttcatcct tgtgggtggt agtagcagga agtgttctgg ctggatttgc ctatagtgta
   160321 gtcttgacga cggtctttca acttgtctct gaacgaattc cagctaaact cctcaatcaa
   160381 gcaacttcat ttgctgtatt aggctgtagt ttcggagcct ttacgacccc atttgttcta
   160441 ggtgcaattg gcttactaac tcacaatggg atgttggtct ttagtatctt aggaggttgg
   160501 ttgattgtaa tctctatctt tgtcatgtac ctacttcaga agagagctta ggattgattc
   160561 ctaagttttt cttttgatac tcaatgaaaa tcaaagagca aactatagtt gattgagttt
   160621 ggaatagtac gctgtagctg ctaaaatatt tctagaaatt aatttgactt tcctaataga
   160681 gttattcata tcttatttca atctactata gaaagctagc cgcaggttgc tcaaaatagt
   160741 gttttgaggt tgcagatgga aactgacgtg gtttgaagag attttcgaag agtatgagat
   160801 ttttataccc atacaatatt tgttttaggt ccttgtttac agactaattt cttgataaaa
   160861 tagaggttat gacgagatat aaagcaacta tttcctatga tggttatgcc tttgctggct
   160921 ttcagcgcca gtctcatgcg cgtagcgttc aggaagaaat tgaaaaaacc ttgaccagat
   160981 taaataaagg gcaagccatt actgttcacg gtgctggtag gacagatagt ggggttcatg
   161041 ccctgggaca ggtcattcat tttgacctgc cttatcagat tgatgaggag aaactccgtt
   161101 ttgccttgga tacccagtct cctgaagata ttgatgtgat ttcgattgag cttgtggcag
   161161 atgattttca ttgccgttat gccaagcata gcaagaccta tgagtttatt gtggatagag
   161221 gacgtcccaa aaatccgatg cgccgtcact atgccaccca ctttccctac ccactcgatg
   161281 tggaacgaat gcagattgca atcaaaaagc tagagggaac ccatgatttt accggtttta
   161341 cagcctctgg gactagtgta gaggataagg ttcgcaccat cacagaagct agtttaatag
   161401 tcgatgagac aggacaattt ttgaccttta ccttttccgg aaatggtttc ttgtataaac
   161461 agattcgcaa tatggtgggg actcttctca aaatcggtaa caaccgcatg ccagtagagc
   161521 agattgatct catcttggag aagaaggaca ggcaacttgc aggtcccact gcagcaccaa
   161581 atggtttgta tttaaaggag attcgttatg aagaataatc gtattttagc actttctgga
   161641 aatgatattt ttagtggtgg tggactgtca gctgatttgg ctacctatac cttgaacggc
   161701 ttgcatgggt ttgtagcagt gacttgtttg acagccttga cagaaaaagg atttgaagtc
   161761 tttccaactg atgataccat ttttcaacat gaattagata gcttgcgtga tgtggaattt
   161821 gggggaatta agattggtct tctccctact gtcagtgtgg ctgagaaggc cttggacttt
   161881 atcaaacaac gcccaggagt acctgtggtg ttggatcctg tcttggtctg caaggaaacg
   161941 catgatgtag ctgtcagtga gctctgccaa gagttgattc gctttttccc ttatgtcagt
   162001 gtgattacgc ctaatctccc agaagcagaa ttattatccg gtcaggaaat taaaaccttg
   162061 gaagacatga aaactgcagc gcagaaattg catgatttag gagcgccagc agtcattatc
   162121 aagggaggca atcgtcttag tcaggacaag gctgtggatg tcttttatga tggacagacc
   162181 tttactatcc tagaaaatcc agttatccaa ggccaaaatg ctggtgcagg ttgtaccttt
   162241 gcctctagca ttgccagtca cttgattaaa ggtgataaac ttttgccagc agtagaaagc
   162301 tctaaggctt tcgtttatcg tgctattgca caagcagatc agtatggagt aagacaatat
   162361 gaagcaaaca aaaacaacta aaatcgccct tgtatcccta ttaaccgccc tttctgtggt
   162421 tctaggttat ttcttaaaaa tcccaacacc tacaggaatt ctaactcttt tagatgctgg
   162481 tgtcttcttt gcggcctttt actttggtag tcgtgaagga gcggtagtcg gaggactagc
   162541 aagtttcttg attgacctct tatcaggcta ccctcagtgg atgttcttta gcttggtcaa
   162601 ccatggcttg cagggatttt tcgcaggatt taaaggaaaa agtcagtggt taggccttat
   162661 tttagcaact attgccatgg taggaggcta cgccttgggt tctactttga tgaatggctg
   162721 ggcagcagcc ctcccagaaa ttctaccaaa tttcatgcaa aatatggtag ggatgattgt
   162781 aggatttatt cttagtcaaa gtatcaagaa gattaagtaa tactcttcga aaatctcttc
   162841 aaaccacgtc agtttccatc tgcaacctca aaacactgtt ttgagcagcc tgcggctagc
   162901 tttctagtct gattttcatt gagcataaag aggttgagta aaaagtcttt caaataagaa
   162961 aaacgcatag tatcaggtgt tgaatgaaca cctgatacta tgcgttttat tgtgggaaga
   163021 ttttcctcat tttctagtga aattgaactt tttctaacat cttttgatag atgacttctt
   163081 aatcaattat catttccatt gttgtttctt ggggtttcat cccttgtctt tgataaaagc
   163141 ggagagcacc ctcgttatca ttccagacac ttagggttag attattgcag ccaatttctt
   163201 tagcataata gcagaaaaat gacaataaaa tagcccctag atattttgaa aggaaagcat
   163261 aggggctata tagtttaatc aaaataaagc aaatctttgc tggtgcttgt aaagaggtcg
   163321 aagccatcct tggtaacaac accgcagtct tcaatacgaa caccgacttt accagggata
   163381 tagatacctg gttcaacaga gaagcacatg ccttcttcga tgaccatgtc gtttccttcc
   163441 atgatagatg ggaattcatg gacatccata ccgataccat gcccgagacg gtggttgaag
   163501 tactcaccat aaccagcttt ttcgatgacc tcacgggcag cgcggtccac ttcatgagca
   163561 gtcacacctg gcttgataaa gtcaagagca gcttgttggg cttcaagagt caagttgtaa
   163621 atatctttct tgaattggtc tggtttgccg acagcgactg tacgagtcat atctgacgca
   163681 tagccattga ccagaacacc caggtcaaag aggagaagag catcattttc aaccttatta
   163741 gctgctggaa tgccgtgtgg attcgcagca ttatcaccag tcaagaccat ggtatcaaag
   163801 ctcatttcgt aaccttcacg tttcatggca aagtcaattt gtgcgatgat atctgtctca
   163861 gtcttatcaa gagaaatatt gtcaaaacca acatgaacag ccttgtcagc ataaagacct
   163921 gcaaccatca ttttttgcac ttcatcagct gatttgatga ggcgcatgcg ttggatacga
   163981 ggagtgaggt tgtcaaactc agcagtctca aaaactgttt tcaaaccatg gtatttggtc
   164041 aagatgagat tgtcaaactc aacagcgaca cgtttgaagt caagttgtgg aagagcatgt
   164101 ttgatttttt gccatggatt ttcagaatcg acatagccca ctactgggaa ggaaacggtg
   164161 ctacttgcac gttctacttc aagagctggg acaaagagga gaggttcctg atctgctagg
   164221 acaaagagga acatttggcg ttcatgggga tcactgtaaa aaccagtgag gtaattgatt
   164281 gtgacggggt cagatacgac agcgacgtct agtttttctg attcaagata tgttaggatt
   164341 tgttgtaatt tagacatatg ctaccttctt tctatccctc tattttggca aaaaatgaga
   164401 gaaaatgcaa gggagaaggg taaaagaaaa gacaaaaaac tccgacaaga taacggagtt
   164461 ctttgatatc attttccttt gtttaagaaa agtcagcctt gcttttgacg tcactgtact
   164521 cttcagcgat ttcttggctg aggatatcct cataggcagg gagttggatg tcctgaccat
   164581 atttcttctt gagggcagta gtaactaggc gataagccag attggcatta cgagagagga
   164641 taggcccgtg gaagtaggaa ccaaagacat tcttataatg aaccccttca ccgacctttt
   164701 cttcgttgtt tccatttcca tagacaacct gtcccagcgg tttttggtca tcagagagga
   164761 aggtacggcc ttggtgattt tcaaatccat agtaggtttc atcgaaatct tcattgtgaa
   164821 tcttgatgtc accgataaaa cggttattgg tctggttgag cgtgtagtgt cccatgaccc
   164881 ctagcccttc gatacgtttt cctgaagctt caacataata ttgacccaat agttggaaac
   164941 caccgcagat agccagaact acaccgtcgt tttggatgta gttgtcaatg ctctcttttt
   165001 tagcaggtag gtcgtctgca atgatacttt gttcaaagtc ttgaccacca ccgaaaaagg
   165061 cgatgtcgta gtgattttca tcaaagtcat catggagaga aacgatgtca acggtcacat
   165121 gggctcccag tttttcagcc acatacttga gcatgaggat gtttccattg tccccgtagg
   165181 tattcatgag atttccgtag aggtgggcaa tgttgagctg ataggggtaa ttgccatctt
   165241 ttgaggaaag tgaagtataa accattagtt catctccttt ctaacaatct gacgactagc
   165301 cagcagttca cgaaattcca gcatggcagt ataagttgcc agaatatagg catgcttgca
   165361 gtcttgattc tcaatggtct tgagaacttg ctccagatta ctcgtttcag tgattttctc
   165421 agctggatag ccagtcactc ggaggcgacg agcgatttca gaatgacgaa caccgccagc
   165481 gttgatttca ggaatgtcca tgtcagtgat ttgttcaaag tctgcatccc agatccagct
   165541 agtgtcaatt ccatctgcat agttggcatt aaggaggaca gataggctaa atggataagg
   165601 tgctagtttg atcatttcga tagcttgggt tgcaccgact ggatttttaa tcaagacaag
   165661 ggtacattcc ttgtcaccga tatgaaaggt ttcttggcgt ccaaagacag cacggctctt
   165721 gtcaaatccc tgtttgatga gttgcgaatc ggcacctagg aaacgggcga tggccacagc
   165781 agctagggcg ttatagatat tatagagccc gccgatttgg ataccgtatt cttggccgtc
   165841 tatgacaaag cgagagcgat tgttggtcaa ctcaaccagt tttgtcaaac gatagtcgag
   165901 atcaggacgt ttacatccac aaccttcaca gatataggta cccaagtttg cataggtatt
   165961 atgctcatat ttgaggatgc cttggcagtc aggacagaga atcccttcgg tattgtagtg
   166021 agccagttgg gctggtcctt tttccaagtc aaaaccaaaa tactctatag ggtttggaat
   166081 agttggcttg tagaaaagtg gactgtctcc gttaaggaga acagtagcag ttggaacttt
   166141 ccgaatggca tccaatatca tgttataggt agtatagatt tcaccgaaac ggtccatctg
   166201 gtcacggaag atattagtaa tgacaaaaag actaggctgg atatagtcac agatacgaga
   166261 tagactggct tcgtcaattt cgaggacggc aatatttttt ccagttttag aagatttggc
   166321 tgttaggaag gttgttgcaa tccctgtaat catgttggca ccgcttggat tggttagaac
   166381 ttgaccatag acctctttta aaatgccgac agtgagggca gttgtcaggg tttttccatt
   166441 tgttccagtg acaacgacaa tctcgtagtt cttagctagg ttttgtaaaa tatctttatc
   166501 aaattgaagg gcgactttac ctgggagcgt acttccacgg ccaagacggc ttaaaatgaa
   166561 gtgggaagaa cgcccagcaa gaaggcccaa agtagttttt aagttcatgt ttctattata
   166621 tcataaaaga ggagaaagac agatttgaga ttccgcagaa gtaaaaacag cccaaagagg
   166681 gctgttcgat acgattaaat ctcaacttaa atcgcaaaca agtcattcaa gttctcagcc
   166741 aaggttgggt gagtgaagat ttgttttgtg aagtaagtgt aaggaatctt gttgtccata
   166801 gcaacagtga tgatgttgat gatttcttga gaaccttctg agaagatgct tgctccaaga
   166861 atttcttttg tttcagtatt gacaacagct ttgaaggcac cgcgaaggtc tccatttacg
   166921 tgaccacgag gcatggctgc aacggggatt tccttaacag cgtatggaag tttcaaatca
   166981 gctgcttggc tttcagtcaa accaacttgt gaaagtgcag gtgtgatgaa catagtattt
   167041 ggcacattga gacggtcttc aagtgtgtag ctgccatctc cagcaaggta gctgtaaaca
   167101 acacggaagt catcaagtga aatgtaagta aattgaaggc caccgttgat atctccaact
   167161 gcaaagacac caggaacgtt tgtttgacag tgtttgtcta ctttaatagc accacgttca
   167221 gttagttcaa tatctgtatt ttcaagttga agtggttcta catttggttt gcgtccagtt
   167281 gcgtagagaa gggcgtcgaa acggtaagtt tcgtcttcag ttacgacaag cacttggtca
   167341 ccatcgtttt tgatttcagt agtatggata ttttgaagca attcaatgcc atcttcttcc
   167401 atgtattgtt tagcaagagc tgcgatggaa ggttctgcac gaggaaggaa agtatccaag
   167461 gcatctagga ctgtgacctt gcttccaagt ttgttgtaaa ggccggcaaa ttcaagaccg
   167521 atatttccgc caccaaggat tccaagtttt tcaggtaatt tgtccaagtt ttggatacct
   167581 gttgagtcaa agatgttttt gcttgtagca agtccaggga ttggcaagac gtttgaaaca
   167641 gcaccagtgt tgatgacgat tgtttcagca gtcagttctt tcttttcatc accagcttgg
   167701 atttcgatga ctttatttga aaggaagtga gcttccgcat caaagatatc tacgcctgta
   167761 ccagcaacag tcgcatagtt tttaccgttg aggcgaccag tgatcgtgtt tttagtagca
   167821 atcacttctt caaaagacaa gtccttttca gcagcaacta gcaaggtttt agttgggata
   167881 caaccaatgt tgatacaagt tccaccgtac atagccttgc tgcgttcaac gagggcaact
   167941 tttttgccag ctgaagccaa tttacctgct agtgttttac cagctttacc aaatccaata
   168001 acaattaaat cgtatgttaa catttatctt cctcctattc gaatttcatt ctagcacaag
   168061 aaaaaaactt ttgcacaatt ctgctacgga aaagacagaa aaagataaaa acgctttcca
   168121 gacaaaaaac tagtaatttt ttgacaagct tgataaacta aaatcctatc tatttttata
   168181 taagatagaa taaatgttcg aaaataggag gttttatgaa atcgaatcgt tatattattg
   168241 cctttgctgg ggtcatttta cacttaatgc tgggttcgac ttatgcttgg agtgtttatc
   168301 gtaaccctat tattgaaaaa acgggatggg atcaggcttc tgttgccttt gcctttagtc
   168361 tagcaatctt ttgtttgggc ttatcggctg catttatggg gcgtttggta gaaaaatttg
   168421 gtccgagagt catggggagt ctatctgctt ttctatacgc aggtggaaat atcttaacag
   168481 gatttgcaat agaccgtcag gagctgtggt tgttgtatct cgcttatggc attttaggtg
   168541 ggcttggttt gggagcaggc tatattaccc ctgtgtcgac gattataaaa tggtttcctg
   168601 ataaacgtgg tctcgcaaca ggtttagcga ttatggggtt tggttttgct tctttattga
   168661 ctagtcccat agcgcaacac ctcatcgcag gggtagggct tgtagaaact ttttatattt
   168721 taggagcaag ttactttatt atcatgctcc tagcttcaca attcattaag cgtccaaatg
   168781 agcaagagct tgcaatttta tcttcttcag ggaaagaaaa aacagcctct ttgacgcaag
   168841 gaatggctgc aaatcaggct ctaaaaagca atcggtttta tatactttgg attattttct
   168901 ttatcaacat agcttgtggt ttaggcttaa tttcagcggc atcgccaatg gcacaggaga
   168961 tggctggctt gtctacaagt catgcagcag taatggtggg cgttttaggg attttcaatg
   169021 gatttggtcg cttgctctgg gcgagcttat ctgactatat cggtcgccct ctaaccttta
   169081 gtatattact gcttgttaat cttttctttt ctctctcact ttggctcttt acagattccg
   169141 ttttatttgt agtcgctatg tctattttga tgacttgcta tggagctggt ttttcattga
   169201 tcccagctta tctcagtgat atttttggaa ccaaggaatt ggccgctctg catggatata
   169261 ttttaacagc ttgggcaatg gctggtttag cgggacctat tttattagca gagacttata
   169321 aaatggctca ttcgtacaca caaaccttgt tcgtttttct cattttatac agtatcgcct
   169381 tggctttgtc ttattatcta ggtcgttcaa tcaaaaaaga aagtcaaaaa ccgcttacat
   169441 gattttctgt agaaatgggg ctatcttttg ctctggtctt gtgttatact agataggttg
   169501 caaagaaaac agtacttttc ttttgtggaa aagaagcaac acgattttat atctagttat
   169561 atgaaaatac gtcataaaaa gaaaagtata aactaagccc tatagggtgg cttcgcacca
   169621 cctttagaaa gaagaataac gtgaaattta atgaattaaa cttgtctgct gatttgctgg
   169681 cagaaattga aaaagctggt tttgtagaag ctagtcctat ccaagaacaa actattcctt
   169741 tggcccttga aggcaaggat gttatcggtc aagctcagac tggtacagga aaaactgcag
   169801 cctttggctt gcctaccctt gaaaaaatcc gtacagaaga agcgactatc caagccttgg
   169861 tcatcgctcc aactcgtgaa ctagctgtcc aaagtcaaga agaactcttc cgctttggtc
   169921 gtagtaaggg agtcaaagtc cgttcagtat atggcggatc aagcattgaa aaacaaatta
   169981 aggctcttaa atctggtgcc catatcgtgg tgggaactcc aggtcgcctc ttggacttga
   170041 ttaaacgcaa ggccttgaaa ttacaaaaca ttgaaaccct tatccttgac gaagcggatg
   170101 aaatgcttaa catgggcttc cttgaagaca tcgaagccat tatttcccgt gtacctgaga
   170161 accgtcaaac tttgcttttc tcagcaacta tgccagatgc catcaaacgt atcggtgttc
   170221 agtttatgaa agcccctgaa catgtcaaga ttgcagctaa ggaattgaca acagaattgg
   170281 ttgaccagta ctatatccgt gttaaggaac aagaaaaatt tgacaccatg actcgtctca
   170341 tggatgtggc acaaccagaa ctcgctattg tatttggtcg taccaaacgc cgtgtggatg
   170401 aattgactcg tggtttgaaa attcgtggct tccgtgcaga aggaattcat ggcgacctag
   170461 accaaaacaa acgtcttcgt gtccttcgtg actttaaaaa tggcaatctt gatgttttgg
   170521 ttgcgacaga cgttgcagcg cgtggtttgg atatttcagg tgtgacccat gtctacaact
   170581 acgatattcc acaagatcct gagagttatg ttcaccgtat cggtcgtaca ggtcgtgctg
   170641 gtaagtcagg tcaatctatt acttttgttg ctccaaacga aatgggttac cttcaaatca
   170701 ttgaaaactt gactaagaaa cgcatgaaag gtctcaaacc tgcaagtgta gaagaatcct
   170761 tccaatcaaa aaaacaggta gctctcaaga aaatcgaacg tgattttgca gatgaaacca
   170821 ttcgtgccaa ctttgagaaa tttggtaagg atgctcgcaa attggctgct gagtttactc
   170881 cagaagaatt ggcaatgtat atcttgagtc tgacagtcca agacccagat agccttccag
   170941 aagtggagat tgcacgtgaa aaaccactac cgtttaaacc atcaggtaat ggtttcggtg
   171001 gtaaagctaa gggaggtcgt ggaggccgtc gtggggacga ccgtcgagag cgtgatcgcc
   171061 gtggcaatgg tcgccgtgat gagttcaaaa aaggaagtcg tggcaacgat cgttttgata
   171121 aggaaaaacg ttaccgtaag gataataaaa aaccacgcaa tactttaagc gaaaagcaaa
   171181 caggctttgt tattcgtaac aaaggcgata aataagaaaa agcggttcaa aatgaatcgc
   171241 ttttttatat aaggagaccg aatgtgaaaa gacaaataaa attattatat tatcttttat
   171301 aatgttatga tacacaaaaa taggcaactt gtcaatagaa aaggaacaat ttaattaaaa
   171361 atattctggt ttttaattaa attgtaagtc aatgcaagtc aataaggaat tttcagataa
   171421 ttattgaaaa agagacgttt ttatgttata atgatagcga ttaaattcga ggtgaaaaat
   171481 ggcacattta ttagaaaaaa ctagaaaaat tacatcaatt ttgaaacgct cagaggagca
   171541 gttgcaggat gagctccctt acaacgctat tacgcgtcag ttagcggata ttattcattg
   171601 caatgcctgc attatcaata gtaagggacg tctgcttggc tattttatgc gttataaaac
   171661 aaatacagat cgcgtagagc aattcttcca aactaagatt ttcccagatg actacgttca
   171721 aggggctaat atgatttacg aaacagaagc aaacttgcct gttgagcatg atatgagtat
   171781 tttccctgtt gagagtagag atgattttcc agatggcttg acgactattg caccgattca
   171841 tgtatcgggg attcgccttg gttctttgat tatttggcgt aatgataaaa aattcgaaga
   171901 tgaggacttg gttcttgttg agattgccag taccgttgtt gggattcagc ttcttaactt
   171961 ccaacgtgaa gaagatgaga aaaatattcg tcgtcgtact gctgtcacca tggcggtcaa
   172021 taccctttct tactccgaac tccgtgctgt ttcagcaatt ttaggggaat taaatggaaa
   172081 tgaagggcag ttgactgcgt cagtgattgc agatcgtatc ggaatcactc gctctgtgat
   172141 tgtcaatgct cttcgtaaac ttgagtctgc ggggattatt gaaagtcgct cacttggaat
   172201 gaagggaacc tatcttaagg tcttgatttc agatattttt gaagaagtga agaaaagaga
   172261 ttactaatga caaaggcttt aatttcgatt gattatacag aagattttgt tgctgatagt
   172321 gggaagctga cagcaggtgc tccagctcag gcgatttcgg atgccattag caaggtaact
   172381 cgattagctt ttgaacgagg agattatatc ttctttacta ttgatgctca tgaagaaaac
   172441 gattttttcc atccggaaag taagttattt cctcctcata atctgattgg gacgagtgga
   172501 cggaatttat atggagattt ggggatcttt tatcaagagc atggttcaga cagtcgtgtc
   172561 ttttggatgg ataaacgcca ttactcagct ttttcaggga ctgacctaga tattcgtttg
   172621 agagagcgta gagtgtctac cgttatctta acaggtgtct tgacggatat ctgtgtccta
   172681 catacagcta tagatgccta taatctagga tatgacatcg agattgttaa accagctgtt
   172741 gcttccatct ggcctgaaaa tcatcaattt gccctaggtc atttcaaaaa tacactcgga
   172801 gctaagttag tagatgaaaa tctaaatgaa ctttctgagt aacctggttg gtgaaaatga
   172861 aaaaatttga aaaaaagtgt tgacaagcat cccaaaagtt gatatactag taaagtaatc
   172921 gatgcgggga tggcggaatt ggcagacgcg caggactaag gatcctgtga ccgctttagg
   172981 tcgtgagggt tcaagtccct ctctccgcat aggaaaagag ttagctaaag ctagctcttt
   173041 tgtatttctc taaaaaatta gaatccagtc aaatgtagtg gagaatcagc gaaaatatgg
   173101 gaaaactgat ccttgtttct gcttttgtca tagaagaata ataaagatta tcttcttcaa
   173161 attctccgat attctctaaa gttttgtgca agttgcacag aactttttta tttttttggt
   173221 catcttgcca tagaaatata aagcgttttc atatataata taattatcaa aagacaaaag
   173281 gagttcacct catggtagaa ttgaatctta aaaatattta caaaaaatat ccaaacagcg
   173341 aacactattc agttgaagat ttcaacttga acatcaaaga taaagaattt atcgttttcg
   173401 taggaccttc aggatgtggt aaatcaacta cactccgtat gattgctggt cttgaagaca
   173461 ttacagaagg tactgcatct atcgatggcg tggttgtcaa cgacgtagct ccaaaagacc
   173521 gtgatatcgc catggtattc caaaactacg ctctttaccc acacatgact gtttatgaca
   173581 acatggcttt cggcttgaaa ttgcgtaaat acagcaaaga agacattaac aaacgtgttc
   173641 aagaagcagc tgaaatactt ggattgaaag aattcttgga acgtaaacca gctgaccttt
   173701 caggtggtca acgtcaacgt gttgccatgg ggcgtgcgat tgtccgtgat gcgaaagtat
   173761 tcttgatgga cgaacctttg tcaaacttgg atgccaaact tcgtgtatca atgcgtgctg
   173821 aaatcgctaa aattcaccgt cgtatcggag ctacaactat ctatgtaact cacgaccaaa
   173881 cagaagcgat gacacttgca gaccgtatcg ttattatgtc agctactaag aaccctgctg
   173941 gtacaggtac tatcggacgt gtagaacaaa tcggtactcc tcaagaagtt tacaaaaatc
   174001 cagttaacaa attcgttgca ggattcatcg gaagcccagc tatgaacttc atcaccgtga
   174061 aattggttgg tagcgaaatt gtttctgacg gtttccgttt gaaagtgcca gaaggagcat
   174121 tgaaagttct tcgtgaaaaa ggctacgaag gaaaagaatt gatctttggt atccgtccag
   174181 aagacgtgaa tgcagaacct gctttccttg aaacattccc agactgtgtt gtaaaagcga
   174241 ctatctctgt atcagaactg cttggttcag aatctcacct ttactgccaa gttggtaaag
   174301 acgagtttgt tgcaaaagtt gatgctcgtg actacttgca aacaggtgca acagttgagc
   174361 ttggatttga cttgaacaaa gcacacttct tcgatgtaga aactgaaaaa acaatctact
   174421 aaaataaata aaattcaaag cactacaaga aaatatatct ctttatcaat tgtagtggag
   174481 agatatcagt taatctaggg agagaaacaa aatgcttctc tcctttttgc tagggaagtc
   174541 atattatgca tctatattgt gatgctcttt atactcttcg aaaatctctt caaaccacgt
   174601 caacgtcgcc ttgccgtacg tatgattact gatttcgtca gttttatctg caacctcaaa
   174661 gatgtacttt gagcagctta cggctagttt cctagtttgc tctttgattt ccattgagta
   174721 ttattgtgag taccatctac aagtgaagct atatgcgtaa actacgtgag caattgaatt
   174781 cgaactagag aggtaataat aaatttatgc tatagttatg gtgacttgta tgcttttgat
   174841 tctagtttat caaataatag attagaattg tcagataata tcattttgtg ttataatgaa
   174901 gaaaaaacag aggtgttcaa atgtcagaag caggtcataa gtttttagca aaattgggga
   174961 aaaaacgctt acgtccaggt ggaaagcgtg ccacagattg gttaattgca gaaggaggat
   175021 tttcaaaaga aaagagaata ctagaggttg cgtgtaatag gggaactaca gcaattgagt
   175081 tggcacagcg ttttggttgc aagataactg ctgttgatat ggatgctcaa gctttagaag
   175141 tggctaaaaa atctgctgga acggcaggtg ttgctcattt aatcagtttt gaaagagcaa
   175201 atgcaatgaa acttccttat caagatgcta gttttgatat tgttataaat gaagctatgc
   175261 tgactatgca agccgatcaa gctaagaaaa aatgtgtaat ggaatatcta agggtattaa
   175321 aacctggagg tcttctcttg acacatgatg tgcttcttaa ggaagctaaa gagtctatca
   175381 gacaggaatt atcacaagca attcatgtaa atgtaggtcc tttaactcaa gatggttggg
   175441 aacaggtgat gatagaatca ggttattgtg atgtgaaagc attgactggt gaaatgacat
   175501 taatgaaatt atcgggtatg atttatgacg aaggtttgct aggaactttg aaaatttgtg
   175561 taaatgcttg taaaaaggag aatagaaagc agtttttaac tatgtataaa atgtttgcta
   175621 agaataaaca gaaattgggc tttattgcga tggctagtta taaatcgtca aaacgttaga
   175681 taattattga agttaacttt tccttttttc tttcttaaaa aatatgctat aatagagagt
   175741 aaaaaacttt gaaagaaaga aaaaagatga atttaaaaga ttacattgca acaattgaaa
   175801 attatccaaa ggaaggcatt accttccgtg atattagtcc tttgatggct gatggaaatg
   175861 cttatagcta cgctgttcgt gaaatcgttc agtatgctac tgacaagaaa gtcgacatga
   175921 tcgtgggacc tgaagctcgt ggatttatcg tgggttgtcc agttgccttt gagttgggaa
   175981 ttggttttgc gcctgttcgt aagccaggta aattgccacg tgaagttatt tctgctgact
   176041 atgaaaaaga gtacggtgtc gataccttga ctatgcacgc ggatgccatt aagccaggtc
   176101 aacgtgttct tattgtagat gaccttttgg cgacaggtgg aactgttaag gcaactatcg
   176161 agatgattga aaaacttggt ggtgttatgg caggttgtgc cttccttgtt gaattggatg
   176221 aattgaacgg ccgtgaaaaa attggtgact acgactacaa agttcttatg cattattaat
   176281 gaaaacagtc cctagggctg ttttctctac actaggatat aaaaatagac tataactagt
   176341 tagagaaaaa ctataattga aaactatatc ttcttgcagt ataataaaag gactaagtgt
   176401 ttgagatttg tcttcaaaca tatgcaatta ttcctgaaag agtacagtta ggagagggtt
   176461 atgccgattc gaattgataa aaaattgcca gctgttgaga ttttacggac agagaatatc
   176521 tttgtcatgg atgatcaacg tgctgcccac caagatatcc gtcctttgaa gattttaatt
   176581 ttaaatctca tgccacagaa aatggtcaca gagacccagt tgttgcgcca cttggctaat
   176641 acacccctac aactggatat tgattttctc tatatggaga gccaccgttc taaaacaact
   176701 cgttcagagc acatggagac cttctataaa acttttcctg aagtcaagga tgagtatttt
   176761 gatgggatga tcatcacggg tgctccagtt gagcatttac catttgagga agtggactat
   176821 tgggaggaat ttagacagat gcttgagtgg tctaagactc atgtctattc gacccttcat
   176881 atctgttggg gggctcaggc tgggctttat ctgcgctatg gtgtagaaaa ataccagatg
   176941 gacagtaagc tatcaggtat ttatcctcag gacaccctaa aagagggtca ccttctattt
   177001 agaggctttg atgatagcta tgtatcccct cattcacggc acacggagat ttctaaggaa
   177061 gaggtcttaa acaagaccaa tctcgagatt ttatcagaag gacctcaggt tggggtttct
   177121 attttggcca gtcgtgattt acgagaaatt tatagttttg gtcatttgga gtatgaccgt
   177181 gataccttgg caaaagagta ttttcgagat cgtgatgcag gtttcgaccc acatattcca
   177241 gaaaattact ttaaagatga tgatgttaat caggtacctt gtctttgttg gtcttcatct
   177301 gcagccctct ttttcagtaa ttgggtaaac catgcggtct atcaggagac gccttttgat
   177361 tggagaaaga tagaagatga tgcatctgca tatgggtatt tataagagga attatgacat
   177421 atttagacgc ttttaaatca ggtaccttgg ttttaccgag tgccctgctc ttgcatttta
   177481 aggaactctt tccttctagc gacgattttc tggtttggca atttttctat ttgcaaaata
   177541 cgacaggctt agaagaaatg tcgccaagcc agattgctga aaggattggc aaggaaattt
   177601 cggatgtcaa ccagtccatt tctaatctga cggaaagggg actgctccag tatcgtacta
   177661 tcgaattaaa tggcgaaatt gaattgctct ttgatgctag tttggccttg gaacgtttgg
   177721 atgacctgtt tggagcagtt cattcaagtt cagaccagct aacacctcaa aaccagctca
   177781 aggatttggt ggaaaccttc cagcaggagt tgggacgatt gttgacgcct tttgagattg
   177841 aggatttgac caagacacta aaggaagatg gaaccagtgc tgacttgatt aaggaggctc
   177901 ttcgtgaagc tgttttgaat ggaaaaccaa actggaagta cattcaggct attttgagaa
   177961 actggcgcca tgaaggaatc aagagtgtgg ctcaaattga ggccaagaga gcagaaagag
   178021 aagcaagcaa tcctcagttg acacaggtat ctgcagattt cagaaatgcc atggatctct
   178081 ggaaggatta atccatgcaa gtaggcttga aatccgagta agatttgcaa gctgtgtata
   178141 attgtgatag aataaataga aaataaattg aaaaaagagg tatgtgaaat gtcacgtaaa
   178201 ccatttatcg ctggtaactg gaaaatgaac aaaaatccag aagaagctaa agcattcgtt
   178261 gaagcagttg catcaaaact tccttcatca gatcttgttg aagcaggtat cgctgctcca
   178321 gctcttgatt tgacaactgt tcttgctgtt gcaaaaggct caaaccttaa agttgctgct
   178381 caaaactgct actttgaaaa tgcaggtgct ttcactggtg aaactagccc acaagttttg
   178441 aaagaaatcg gtactgacta cgttgttatc ggtcactcag aacgccgtga ctacttccat
   178501 gaaactgacg aagatatcaa caaaaaagca aaagcaatct ttgcgaacgg tatgcttcca
   178561 atcatctgtt gtggtgaatc acttgaaact tacgaagctg gtaaagctgc tgaattcgta
   178621 ggtgctcaag tatctgctgc attggctgga ttgactgctg aacaagttgc tgcctcagtt
   178681 atcgcttatg agccaatctg ggctatcggt actggtaaat cagcttcaca agacgatgca
   178741 caaaaaatgt gtaaagttgt tcgtgacgtt gtagctgctg actttggtca agaagtcgca
   178801 gacaaagttc gtgttcaata cggtggttct gttaaacctg aaaatgttgc ttcatacatg
   178861 gcttgcccag acgttgacgg tgcccttgta ggtggtgcgt cacttgaagc tgaaagcttc
   178921 ttggctttgc ttgactttgt aaaataatca gtaagtagca aaagctaggt ggaacagcat
   178981 tcagatgtct gttacatttt ttataggaga gcaaagattg aaaacaaaaa ttggattagc
   179041 aagtatctgt ttactaggct tggcaactag tcatgtcgct gcaaatgaaa ctgaagtagc
   179101 aaaaacttcg caggatacaa cgacagcttc aagtagttca gagcaaaatc agtcttctaa
   179161 taaaacgcaa acgagcgcag aagtacagac taatgctgct gcccactggg atggggatta
   179221 ttatgtaaag gatgatggtt ctaaagctca aagtgaatgg atttttgaca actactataa
   179281 ggcttggttt tatattaatt cagatggtcg ttactcgcag aatgaatggc atggaaatta
   179341 ctacctgaaa tcaggtggat atatggccca aaacgagtgg atctatgaca gtaattacaa
   179401 gagttggttt tatctcaagt cagatggggc ttatgctcat caagaatggc aattgattgg
   179461 aaataagtgg tactacttca agaagtgggg ttacatggct aaaagccaat ggcaaggaag
   179521 ttatttcttg aatggtcaag gagctatgat gcaaaatgaa tggctctatg atccagccta
   179581 ttctgcttat ttttatctaa aatccgatgg aacttatgct aaccaagagt ggcaaaaagt
   179641 gggcggcaaa tggtactatt tcaagaagtg gggctatatg gctcggaatg agtggcaagg
   179701 caactactat ttgactggaa gtggtgctat ggcgactgac gaagtgatta tggatggtgc
   179761 tcgctatatc tttgcggcct ctggtgagct caaagaaaag aaagatttga atgtcggctg
   179821 ggttcacaga aatggtaaac gctatttctt taataataga gaagaacaag tgggaaccga
   179881 acatgctaag aaaatcattg atattagtga gcacaatggt cgtatcaatg attggaaaaa
   179941 ggttattgat gagaacgagg tggatggtgt cattgttcgt ctaggttata gcggtaaaga
   180001 agacaaggaa ttggcgcata acattaagga gttaaaccgt ctgggaattc cttatggtgt
   180061 ctatctctat acctatgctg aaaatgagac cgatgctgag aatgacgcta aacagaccat
   180121 tgaacttata aagaaataca atatgaacct gtcttaccct atctattatg atgttgagaa
   180181 ctgggaatat gtaaataaga gcaagagagc tccaagtgat acagacactt gggttaaaat
   180241 catcaacaag tacatggaca cgatgaagca ggcgggttat caaaatgtgt atgtctatag
   180301 ctatcgtagt ttattacaga cgcgtttaaa acacccagat attttaaaac atgtaaactg
   180361 ggtagcggcc tatacgaatg ctttagaatg ggaaaaccct tattattcag gagaaaaagg
   180421 ttggcaatat acctcttctg aatacatgaa aggaatccaa gggcgcgtag atgtcagcgt
   180481 ttggtattaa gcgatgattt gaaagaggga tgtgatagta gcaccctctt tttctttgtt
   180541 ttatgatagt tcatcctcga gtaaattcaa gatcttgctc ggaaatgaag cttatatagt
   180601 agattgaata tagacaaata ccttgtgatt ggtaaaacat tttagaaatt catttacctt
   180661 tcctaatcga cttggtttca tcttatttca atctattata gtattgggga atttcttcaa
   180721 accacatcag cttggtcagt tctacctgcg acctcaaaac ttgtgctttg gtcaagctgg
   180781 gtttagtttc ctagtttgct gatggatttc cattgactat aagcatccaa ccctcttttt
   180841 gtcttctaaa gaattcttaa attatcagtc tattgcaact tttctcatat aagttctttg
   180901 tcttgctatt tgttttcctt agtagtatac taaggtagta atcattaaga agtggttaca
   180961 aaaaataatg aatgaggtaa agaaaatggt agaattgaaa aaagaagcag taaaagacgt
   181021 aacatcattg acaaaagcag cgccagtagc attggcaaaa acaaaggaag tcttgaacca
   181081 agctgttgct gatttgtatg tagctcacgt tgctttgcac caagtgcact ggtatatgca
   181141 tggtcgtggt ttccttgtat ggcatccaaa aatggatgag tacatggaag ctcttgacgg
   181201 tcaattggat gaaatcagcg aacgcttgat tacactcggt ggaagcccat tctctacatt
   181261 gacagagttc cttcaaaata gtgaaatcga agaagaagct ggtgaatacc gtaatgttga
   181321 agaaagcttg gaacgtgttc ttgttatcta ccgttacttg tcagaacttt tccaaaaagg
   181381 tttggatgtc actgatgaag aaggtgacga tgtgacaaac ggtatctttg caggcgctaa
   181441 aactgaaaca gataaaacaa tttggatgct tgcagccgaa cttggacaag cacctggttt
   181501 gtaagaaata aggaaacata gataaatctg taggaaattt cttacagatt ttttctattt
   181561 tgtaagctat tccaaaccag tctttttttg agttttttga taaaatagta ctatcagtga
   181621 aaaggatgga agcatgacta agaaaatcgt agctatttgg gcccaggatg aagagggtgt
   181681 gattggtaag gaaaatcgtc tgccttggca tttgccagca gaattgcagc actttaaaga
   181741 aacaactctg aatcatgcta tcttgatggg gcgtgtgacc tttgatggga tggggcgtcg
   181801 cttgcttcca aaacgggaaa ccctgatttt gacgcgtaat ccggaagaaa agatagatgg
   181861 ggttgctact tttcaggacg tccagtctgt tcttgactgg tatcaggatc aagaaaagaa
   181921 tctctacatt atcggtggga agcaaatttt tcaggctttt gaaccttacc ttgatgaagt
   181981 gattgtcact cacattcatg ctcgggtgga aggagatacc tatttccctg aagagcttga
   182041 cttgtctctt tttgagacag tttcaagcaa attttacgcc aaagatgaga agaatcctta
   182101 tgattttacc atccaatacc gcaagagaaa ggaagtataa tggaacggag tttatttggt
   182161 ctattcacgg cttttctgtg tttcatctgc tttctggcag gagcacaggc ttttcgtaaa
   182221 aagcgttacg ggctttctat cctcctttgg ttaaatgcct ttaccaatct ggtcaatagt
   182281 attcatgctt tttacatgac cttattttag atagaatgac agtatagaat ggaaggaaat
   182341 catgtctaca aatagaaaaa atgatatgat ggtttattgc tcattttgtg gcaaaaacca
   182401 agaagaagta caaaaaataa ttgctggcaa caatgctttt atttgtaatg aatgcgtgga
   182461 gttagctcag gaaatcattc gagaagaatt ggttgaggaa gtcttggcag acttgtctga
   182521 ggtgccaaaa ccaattgaac tcctccatat cttgaaccac tatgtaattg gtcaagatcg
   182581 tgccaagcgt gccttggcag tggcggttta taaccactac aaacgcatca atttccacga
   182641 tacacgcgaa gagtcagaag atgtggattt gcagaagtca aacattttga tgattggccc
   182701 aactggttca gggaaaactt tccttgccca gaccttggct aagagcttga atgtgccttt
   182761 tgctattgcg gatgcgacag ctctgacgga ggctggttat gtgggtgagg acgtggaaaa
   182821 tatcctcctc aaactcttgc aggttgctga ctttaacatc gaacgtgcag agcgtggcat
   182881 tatctatgtg gatgaaattg acaagattgc caagaagagt gagaatgtgt ctatcacacg
   182941 tgatgtttct ggtgaagggg tgcaacaagc ccttctcaag attatcgagg gaactgttgc
   183001 tagcgtgccg cctcaaggtg gacgcaaaca tccacaacaa gagatgattc aagtggatac
   183061 aaaaaatatc ctcttcatcg tgggtggtgc ttttgatggt attgaagaaa ttgtcaaaca
   183121 acgtctgggt gaaaaagtca tcggatttgg tcaaaataat aaggcgattg acgaaaacag
   183181 ctcatatatg caagaaatca tcgctgaaga cattcaaaaa tttggtatta tccctgagtt
   183241 gattggacgc ttgcctgttt ttgcggctct tgagcaattg accgttgatg acttggttcg
   183301 catcttgaaa gagccaagaa atgccttggt gaaacaatac caaactttgc tttcttatga
   183361 tgatgttgag ttggaatttg acgacgaagc ccttcaagag attgctaata aagcaatcga
   183421 acggaagaca ggggcgcgtg gacttcgctc cattatcgaa gaaaccatgc tagatgttat
   183481 gtttgaggtg ccgagtcagg aaaatgtgaa attggttcgc atcactaaag aaactgtcga
   183541 tggaacggat aaaccgatcc tagaaacagc ctagaggtga ctatggaact taatacacac
   183601 aatgctgaaa tcttgctcag tgcagctaat aagtcccact atccgcagga tgaactgcca
   183661 gagattgccc tagcagggcg ttcaaatgtt ggtaaatcca gctttatcaa cactatgttg
   183721 aaccgtaaga atctcgcccg tacatcagga aaacctggta aaacccagct cctgaacttt
   183781 tttaacattg atgacaagat gcgctttgtg gatgtgcctg gttatggcta tgctcgtgtt
   183841 tctaaaaagg aacgtgaaaa gtgggggtgc atgattgagg agtacttaac gactcgggaa
   183901 aatctccgtg cggttgtcag tctagttgac cttcgtcatg acccgtcagc agatgatgtg
   183961 cagatgtacg aatttctcaa gtattatgag attccagtca tcattgtggc gaccaaggcg
   184021 gacaagattc ctcgtggtaa atggaacaag catgaatcag caatcaaaaa gaaattaaac
   184081 tttgacccga gtgacgattt catcctcttt tcatctgtca gcaaggcagg gatggatgag
   184141 gcttgggatg caatcttaga aaaattgtga ggaaaagaaa atggcaaaaa caattcatac
   184201 agataaggcc ccaaaggcta tcggacccta tgttcaagga aaaatcgttg gcaacctttt
   184261 gtttgctagc ggtcaagttc ccctatcccc tgaaactggg gaaattgtag gagagaatat
   184321 ccaagaacag acagagcaag tcttgaaaaa catcggtgct attttggcag aagcaggaac
   184381 agactttgac catgttgtca aaacaacttg tttcttgagc gatatgaacg actttgttcc
   184441 ttttaatgag gtttaccaaa cggccttcaa agaggaattc ccagctcgtt cagctgtgga
   184501 ggtagctcgt cttcctcgtg atgtaaaagt cgaaattgaa gtcatcgcag agattggata
   184561 agctagttga agtttggtgt tgccaaactt cttttgatat aaggagaaaa agatgacaaa
   184621 gaaacaactt cacttggtga ttgtgacagg gatgagtggc gcagggaaaa ctgtagccat
   184681 tcagtccttc gaggatctag gttatttcac cattgataat atgccgccag ctctcttgcc
   184741 taagtttttg cagctggttg aaattaagga agacaatcct aagttggcct tggtagtgga
   184801 tatgcgtagc cgttctttct tttcagagat tcaagctgtt ttggatgagt tggaaaatca
   184861 agatggtttg gatttcaaaa tcctcttttt ggatgcggct gataaggaat tggtcgctcg
   184921 ttacaaggaa accagacgga gtcacccact agcagcagac ggtcgtattt tagatggaat
   184981 caagttggaa cgtgaactct tggcaccttt gaaaaatatg agccaaaatg tggtggatac
   185041 gactgaactc actccacgtg agctgcgcaa aacccttgca gagcagtttt cagaccaaga
   185101 acaagcccag tctttccgta tcgaagtcat gtctttcgga tttaagtatg gaatcccgat
   185161 tgatgcggac ttggtctttg atgtccgttt cttgccaaat ccctattatt taccagaact
   185221 gagaaaccaa acgggtgtgg atgaacctgt ttatgattat gtcatgaacc atcctgagtc
   185281 agaagacttt tatcaacatt tattggcctt gattgagccg attctgccaa gttaccaaaa
   185341 ggaaggtaag tccgttttga ccattgccat gggatgtacg ggtggacaac accgtagtgt
   185401 ggcatttgct aaacgcttgg tgcaggactt atccaagaat tggtctgtta atgaagggca
   185461 tcgcgacaaa gaccgcagaa aggaaacggt aaaccgttca tgagaaaacc aaagataacg
   185521 gtgattggtg gagggactgg aattcccgtc attctaaaaa gtctgcggga aaaagatgtg
   185581 gaaatcgcag ctatcgtgac ggtggcagat gatggtggtt cttcaggtga actccgaaaa
   185641 aatatgcaac agttgacacc gccaggtgat tttcgtaatg tccttgtggc catgtcggat
   185701 atgcctaagt tttatgagaa ggtctttcag tatcggttct ctgaggatgc cggagccttt
   185761 gctggccatc cattgggaaa tctcatcatt gctggcttgt cagaaatgca gggttcaacc
   185821 tataatgcca tgcagttatt gagcaaattt ttccatacaa cagggaaaat ttatccttcc
   185881 agtgaccatc ctttgaccct tcatgcagtc tttcaggatg ggacagaagt ggctggagag
   185941 agtcatattg tagaccatcg aggcataatt gacaatgtct atgtgaccaa tgccctaaac
   186001 gatgatacgc ctctggccag ccgtcgagta gtgcagacca tccttgaaag tgacatgatt
   186061 gtcctagggc caggttctct ctttacctct attttgccca atatcgtgat taaggaaatt
   186121 gggcgggctc ttttggaaac caaggcagaa attgcctatg tctgcaatat catgacccaa
   186181 cgtggggaga cggaacactt tacagatagc gaccacgtgg aagtcttgca tcgtcacctt
   186241 ggtcgccctt ttatcgacac tgtcttggtg aatattgaaa aagtgcctca ggaatacatg
   186301 aattccaacc gttttgatga atacttggtg caagtggaac acgattttgt aggtctttgt
   186361 aagcaagttt cgcgcgtgat ttcatctaac ttccttcgtc tggaaaatgg cggtgccttc
   186421 cacgatggag atttgattgt ggacgagttg atgcgcatta tacaggtgaa aaaatgagtt
   186481 tcacagtagc agtaaaagaa gaaatcctgg gccaacacca tctgagctgg catgaattat
   186541 ctgccattat caaaatgtct ggtagcatcg gtctctcgac ttcgggcttg actttgtcag
   186601 ttgtgacaga aaatgccaaa ctggcccgtc acctctatga gtcctttctc catttctatg
   186661 aaatcaaatc tgaaattcgt caccaccaac ggagcaatct tcgcaagaat cgcgtctata
   186721 ccgtttttac agatgaaaag gtgcaggatt tgttaagtga tttgcacttg gcagactctt
   186781 tctttggcct ggaaacaggt attgatgagg cgattttatc ggatgaggaa gcaggtcgtg
   186841 cctatctctg tggcgctttc ttggcaaatg ggagcattcg tgaccctgag tcaggcaagt
   186901 accagttgga aatcagttct gtttatctgg accacgcgca aggaattgcc tcccttctcc
   186961 aacagttttt actggatgcc aaggtgcttg agcgcaagaa gggggctgtg acctatctcc
   187021 agcgagcaga agacattatg gacttcttga tagtaatcgg agccatgcag gcacgtgatg
   187081 attttgagcg ggttaagatt ttgcgagaaa cccgtaacga cctcaatcgg gctaataatg
   187141 ccgagacagc taatatcgct cggacagttt ctgccagcat gaagaccatt aacaatatca
   187201 gtaaaataaa agatatcatg ggcttagaaa atttgccagt agatttgcag gaagtggcgc
   187261 aactgaggat tcagcaccca gactactcta tccaacagtt ggcagatagc ctcagcaccc
   187321 ctctgaccaa aagtggtgtc aatcacagac tcagaaaaat caataagata gccgatgaat
   187381 tataaaacca cgaatcctat gtgactcgtg gttctttttt ataaactagt agagtgtttt
   187441 ggttgtactt tttgttcagg gtcaatgtag ttgatagcgt tgttgacagc agttggagct
   187501 tctccgaggc ctgtcgcaat cagatcaatt tttccgtcat agtagcagca gtcaccgata
   187561 gcatagatac ctgcttggct ggattcctgt ttgctgttga cgataatctt gtgacggttg
   187621 aggtcgagcc cccagttttt aaggttaccg acagaagatt tgaaaccata gttgacaaag
   187681 aggtggtcta ggtcaatggt ttcagtttca tcagatttga cttttgtgat ttcaagttta
   187741 tcaagtgttt ttccatttcc aaggagttgg ctaggggcga atggtgtctt gatggttaca
   187801 gatgattctt gcaaggcttg aacactgtgt tccaaggcac ggaaattatc tctgcggtga
   187861 acaagggtag ttggtgcgat tttttcaaaa gccaaagccc aatccacagc cgagtctccc
   187921 ccaccaagaa tcgtcacttt cttaccagcg tattgctgaa tgttagaaac gtggtagtgg
   187981 atattttcat agccctcaac actttcaagt tccagcggac gtggtttgaa ggcaccgcca
   188041 cccatagcga tgataactgt tttagtcagg tgacttcctt tagaagttgt gatggcaaat
   188101 tcttcttctt gtttgtcaat ctcaagaacc gtttcattga gatgaatagg ggtatcaaat
   188161 ccatttagct gttcaatcaa gcggttagtc aactcttctc cagtcaggtt tgggaagcct
   188221 ggtacgtcta ggatttcctt ttcagggtag agaatagcag gttgtccacc tagctgggga
   188281 agagagtcga tgatttgaac cttggcttgg cgtaggtggg cataaaaggc tgcaaaaagc
   188341 ccgacaggac caccacccac aatggtaata tcatagagtt gagacatagt ttctcctttg
   188401 ttttttctag tcagtttatt ttatcatatt tttgttcaat gtaaaatgaa ctaggatagg
   188461 gaaaaaaatg ccagaaaatg gtataatagg acgaaagtgt tttgataggg aggatatcag
   188521 ggatgaattt tcaacaatta tccaatctgc aatattggac cagtttgttt gcaagtccat
   188581 ggacgatagc tatcaatctg attgatattt tgattgttgc ttatatttta taccatttta
   188641 caaaagctat tgcaggaacc aagattatga ttttggtacg tggagttttg gtgtttattt
   188701 tagctcaaat ccttgcaaat atgattggtt tgactacgat ttcttggtta atcaatcaaa
   188761 ttattactta tggggttatt gcggcggttg ttatcttctc tccagagatt cggactggtt
   188821 tggaacgttt gggaagagcg acagatttct tttccaatgc ccctattagt gctgaggaac
   188881 agatgattcg tgcctttgtt aagtctgttg aatacatgag tcctcgtaaa atcggggcct
   188941 tggttgctat tcagcgtgta cgtaccttgc aggagtatat gtcgacagga attcccttgg
   189001 atgctaagat ttctgcagaa cttctcatta acatttttat tcccaacact cccctacatg
   189061 acggtgcggt gattatcaaa gaagaacgta tcgctgtgac gtctgcctat ctgcccttga
   189121 caaaaaacac agggatttcc aaggaatttg ggaccagaca ccgggcggct atcggtttat
   189181 cagaagtctc agatgccttg acttttgtcg tatcagagga aacgggagga atttcgataa
   189241 cctataatgg aaggtttaag cacaacctaa cacttgatga atttgaaaca gaattacgtg
   189301 aaatcttact tccaaaagag gaagtgggtc ttagttttaa agaacgattg ctaggaggat
   189361 ggaaacatga aaaaaaatag tttatatatc atatcctcac tcttttttgc ttgtgtctta
   189421 tttgtctatg ctacggcgac gaattttcaa aacagtacca gtgctaggca ggtaaaaacg
   189481 gaaacctata ctaatacagt aacaaatgtc cctattgaca tacgctataa tagtgataag
   189541 tattttatta gcggttttgc ttcagaagta tcagtggtct tgactggtgc aaatcgccta
   189601 tcgctagcta gtgaaatgca agaaagtaca cgtaaattca aggttactgc tgacctaaca
   189661 gatgccggtg ttggaacgat tgaagttcct ttgagcattg aagatttacc caatgggctg
   189721 accgctgtgg cgactccgca aaaaattaca gtcaagattg gtaagaaggc tcaaaaggat
   189781 aaggtaaaga ttgtaccaga gattgaccct agtcaaattg atagtcgggt acaaattgaa
   189841 aatgtcatgg tgtcagataa agaagtgtcg attacgagtg accaagagac attggataga
   189901 attgataaga ttatcgctgt tttgccaact agcgaacgta taacaggtaa ttacagtggt
   189961 tcagtacctt tgcaggcaat cgaccgcaat ggtgttgtct taccggcagt tatcactccg
   190021 tttgatacaa taatgaaggt gactacaaaa ccagtagcac caagttcaag cacatcaaat
   190081 tcaagtacaa gcagttcatc ggagacatct tcgtcaacga aagcaactag ttcaaaaacg
   190141 aattaaaaat agaaaaggat tttataacaa tgggtaaata ttttgggact gatggagtcc
   190201 gtggagaagc taacctagaa ctaacaccag aattagcctt taaactagga cgttttggag
   190261 gctatgttct tagtcaacat gaaacggaag cgccgaaagt ctttgtagga cgtgacacac
   190321 gtatttcagg ggaaatgctg gaatcggcct tggtggcagg tctcctttca gtagggattc
   190381 acgtatacaa acttggtgtc cttgcaacac cagcagtagc ttacttggtt gaaactgaag
   190441 gagcaagtgc cggtgtcatg atttctgcta gccacaaccc agcccttgat aacggaatca
   190501 agttctttgg cggtgatggc ttcaaactag atgatgaaaa agaagcagaa attgaagcct
   190561 tgctagatgc tgaggaagac actcttcctc gtccaagtgc agaaggctta ggaattttgg
   190621 tagattatcc agaaggcttg cgtaagtatg aaggatacct tgtttcaact ggaactcctc
   190681 ttgatggaat gaaggttgcc ttggatacag ctaatggagc agcttctacc agtgcccgtc
   190741 aaatctttgc agaccttggt gcccaattga cggttatcgg ggaaacacca gacggtctta
   190801 acatcaacct taatgttggt tcaacacatc cagaagccct tcaagaagtg gtcaaagaaa
   190861 gtgggtcagc tattggtttg gcctttgatg gagacagtga ccgcttgatt gctgttgatg
   190921 agaatggtaa catcgtcgat ggtgacaaga ttatgtacat catcggaaaa tacctttctg
   190981 aaaaaggaca attggctcaa aatacaattg tgacaactgt tatgtctaac cttggtttcc
   191041 acaaggcctt gaatcgcgaa ggtattaaca aggcagttac tgcagttggt gaccgctacg
   191101 ttgttgaaga aatgagaaaa tcaggctaca accttggtgg tgaacagtct ggtcacgtta
   191161 tcttgatgga ttacaatacc acaggtgatg gtcaattatc agcagttcaa ttgactaaaa
   191221 tcatgaagga aactggtaag agcttatcag agttggcggc agaagtaacg atttatccac
   191281 aaaaattagt taatatccga gtggaaaacg tcatgaagga aaaggccatg gaagtgccag
   191341 ctatcaaggc catcatcgag aagatggaag aagaaatggc ggggaacggc cgtatccttg
   191401 ttcgtccaag tggaacagaa cccctcttgc gtgttatggc agaagcgcct acaacagaag
   191461 aagtagacta ctatgttgat accatcacag atgtagttcg tgctgaaatt gggattgact
   191521 aaatcctaga aaactagatg aaaataaaaa attatggtac aatagcttat aatattgtag
   191581 ccgatggaga aagacatgaa tcttaaacgt gaacaagaat ttgttagtca gtatcatttt
   191641 gatgcgcgta attttgaatg ggaaaatgaa aatggagctc ctgaaaccaa ggtggatgtg
   191701 aatttccaat tgctccaaca tgaccaagaa aatcaagtga cttccttgat tgtcatcttg
   191761 agctttatga ttgtatttga taagtttgtc attagtggaa caatctcaca agtaaaccat
   191821 atcgatggcc gtattgtcaa tgaaccaagt gaattgaacc aagaagaggt ggaaaccttg
   191881 gctcgtccat gtttgaacat gctcaatcgt ttgacttacg aagtgactga aattgcatta
   191941 gacttaccag gaattaattt ggagttctaa tatgaaatta gctgttttca cagattcctc
   192001 tgcttatctc agtgaagaga ccttgcaaag agaagacttg tttgtcttgg atattcctgt
   192061 caatattgat ggtgaggaat atgtcgaagg catcaatctg tctgctgagg aattttacca
   192121 aaaaatggct caggcttctg aattgcctaa gaccagtcaa ccaagtattg ccaagttaga
   192181 tgagatctta acttcgctca aagaacaagg ctatacacat gccttggggc ttttcctatc
   192241 ttctggaatt tcaggttttt accaaaatat ccagtatatg gtcgatgact atgagggctt
   192301 aaccattgct ttcccagaca ctttgattac aagtgctccc ctaggcatca tggttgaaag
   192361 cgtctttaat tggcgtgatc agggcgatga ttttgccagc attcaggata agctagccat
   192421 tcaaatcagc cgtacgtcag cctttatcat ggtagatgac ttggatcatt tggtaaaagg
   192481 tggacgcctt tcaaatgggg ctgccatttt gggcaatttg cttagcatta agccaatcct
   192541 ttattttaac gatcaaggtg tgattgaagt ttacgaaaaa gttcgtactg aaaagaaggc
   192601 caccaagcgc ttaattgaaa ttatcaagga aacaacggct tcaggtcaat accgggtcat
   192661 tgtcattcat gggaatgctc ctgaaaaggc tgaagaattg cgtcagcact tgcttgattt
   192721 tggcttgggt tcggatgttt cacttgctac atttggtagt gtcattggaa cgcacctagg
   192781 agcaggaagt attgctctgg gttatattcc agtgatttag ttggcgcttc taggctagtt
   192841 aagatgcctt gtatcttaga aattgaacac ggactacctg cctcttgaaa aaagatgcct
   192901 gtcttgcctt tcgtggaaag tcagtgccat tccctatttt tcagaggcag ctaaggtcct
   192961 ttgtatcttg ataattgaac acgcctggaa ccctgtgtga aaaagatagt tcttccaaga
   193021 agtagacact tcttgattgg aattcctatt ttcactttgt gttcttacgg actttgtatc
   193081 ttagacagga gtagagatga gtattcgagt aattattgcc ggttttaagg gaaagatggg
   193141 ccaggctgct tgtcagatgg tattgactga tccagacttg gacttggtag cagttttgga
   193201 tccttttgag tctgagtcag aatggcaggg tattcctgtt ttcaaggata aggctgattt
   193261 agctggtttt gaagcggatg tctgggtaga ttttactact ccagctgttg cctacgaaaa
   193321 tacacgtttt gctcttgaaa atggctttgc tccagtagtt ggaacgactg gtttcacgag
   193381 tgaagaaatt gcagagctaa aagaattttc tcgtgcccaa gacttgggtg gcctgattgc
   193441 ccctaacttt gccttgggtg ctgtcttact catgcaattt gcgacgcagg ctgccaaata
   193501 tttcccaaat gtggagatta ttgagctcca tcatgacaag aaaaaggatg ctccgagtgg
   193561 aacagccatt aaaacagctg agttgatggc agaggttcga gagtccattc agcaaggcgc
   193621 agcagatgag gaagagctga ttgctggtgc tcgtggtgct gactttgatg gtatgcacat
   193681 ccactcagtt cgtttgccag gtttggtagc ccatcaggaa gtcatctttg gcaatcaggg
   193741 agaagggttg accctccgtc atgactccta tgatcgcatc tccttcatga caggagtcaa
   193801 tttgggaatt aaagaagttg tcaagcgtca tgagcttgtc tatggattag aacacttatt
   193861 atgagattaa cgcaaatgcc ttctgaattt cagaaggctt taccagtatt agaaaaaatt
   193921 aaagaagcag gctttgaggc ttattttgtt gggggctctg ttcgagatgc ccttctccat
   193981 aaccctatcc acgatgtgga tattgcgacg tcttcttatc cagaagagac caagcagatt
   194041 tttccgcgaa cagccgatat cggaatcgag catggaaccg tcttggtctt agatggggat
   194101 gaggagtatg aggtaacaac ctttcggaca gaggatgtct atgtggacta tcgcagaccc
   194161 agtgcggttt cctttgtgcg ctcgctagaa gaagacctca aacgccgtga tttcacagtc
   194221 aacgcctttg ccttggatga gacaggagaa atcgttgact tgttccatgg tttagaagat
   194281 ttggaaaagc aagtcttgcg agcagttgga gtggctagtg agcgtttcaa cgaagatgct
   194341 ttacggatta tgcgtggttt ccgttttcag gctagtcttg gttttgcact tgaaccagaa
   194401 acatttaaag ctatgaagac cttgacgccg cttttggaga acatttctgt agagcgtacc
   194461 ttcgtcgagt ttgataaact cttgctggct ccattttgga gaaggggctt ggcttccatg
   194521 attgagagtc aagcttatga ctatctccct gatatggcat ctagccagga caagctcaac
   194581 agactgtttg atttggagac tgattttact tttgaatcct ctgaacaagc ctgggcggct
   194641 ttactatggg ctttggagat tgaaaatgcg cagtcatttt tgaaatcttg gaagacctca
   194701 cgccagtttg ccaagcaagt tcaggatttg ctgattattt tggctctgcg tgaaaatgga
   194761 gaattgagca agcgagattg ttatcgcttt gacatagatt tgcttttaca ggctgaaaat
   194821 cttcgtcaag ctcaaggaaa agaagtcaac ccacaagcca tcacagaaaa ataccaaagc
   194881 ttgactatcc atgacaagaa agagattcag attaatggcg gtattttgat caaggaatat
   194941 ggctatcagc caggcccaga cttgggagag attttaacag agattgagtt tgccattgtc
   195001 gatggagaat tggagaataa tcgtgaagcc atccatgctt acctgaggga gaaaaaatga
   195061 gtgattttat cgttgaaaaa ctaagtaaat ccgttggtga caagaccgtt tttagggata
   195121 tttcctttat tatccatgac ttagacagaa ttggtttaat cggtgtcaat gggactggca
   195181 agaccaccct tttggacgtc ctttctggtg tttctggatt tgatggggat gtcagtcctt
   195241 tttcagctaa aaatgattac cagattggtt acttgactca ggatcctgat tttgatgata
   195301 gaaagacagt tttggatacg gttctatcta gtgaactcaa ggaaatccag ctcattcgtg
   195361 agtatgaatt gattatgctc gactatagtg aggacaagca ggcgcgtttg gaacgtgtca
   195421 tggcagagat ggactctctc caagcttggg aaatcgaaag tcaggtcaag accgttctta
   195481 gcaaattggg cattcaagac ttatctactc ctgttgggga attgtcaggt ggtctgagaa
   195541 gacgggtaca gttggcacaa gtcttacttg gcaaccacga cctcttgctt ttggatgagc
   195601 cgaccaacca tctggatatt gcgattattg agtggctgac cctctttttg aaaaattcta
   195661 agaagaccgt cctttttatc actcacgatc gttatttctt agacgctttg tcaacacgga
   195721 ttttcgagtt ggatcgtgca ggcttgaccg agtaccaggg aaattaccag gactatgttc
   195781 gcctaaaggc ggaacaggat gagcgcgacg cggctcttct tcacaaaaaa gaacaactct
   195841 acaaacaaga attggcctgg atgcgcagac aaccgcaggc gcgtgcgacc aagcagcagg
   195901 cccgtatcaa tcgattccat gatctgaaaa aggaagtttc aggcagtagt gctgagacag
   195961 acttgaccat gaactttgaa accagtcgga ttgggaagaa agtcatcgag tttcaggctg
   196021 tttcctttgc ctatgaaaac aagcctattt tgcaagattt taatctcttg gtgcaggcca
   196081 aagaccgtat cggaatcgtt ggggacaatg gtgttggaaa atcaaccctg ctcaacttga
   196141 ttgcaggaag tcttgagcca actaaaggac aagttgtgat tggggaaact gttcgcatcg
   196201 cctatttctc tcagcaaatt gagggtttgg atgaaagcaa gagagttatc aattacctgc
   196261 aggaagtggc agaagaggtc aagaccagtg gcggttctac gacttcgatt gcagagttgc
   196321 tggagcagtt ccttttccca cgttcgacgc atggaacctt gattgagaaa ttgtcagggg
   196381 gtgagaaaaa acgtctttat ctcctcaaac tgcttttgga aaaaccaaat gttcttcttt
   196441 tagacgagcc aaccaatgac ctagatattg caactttgac agtcttagag aatttcttgc
   196501 aaggttttgc aggtcccgtt ttaacagtca gtcacgaccg ctatttcttg gataaggtag
   196561 cgaccaagat tctcgctttt gaggatggca agattcgtcc tttctttggt cattacaccg
   196621 actatcttga tgaaaaagct tttgaaacag atatggccaa tcaagtgcaa aaggtcgaaa
   196681 aggaaaaagt ggtcaaggtt cgagaagaca agaaacgcat gacctaccaa gaaaagcagg
   196741 agtgggcaag tattgaaggt gatattgaaa ccttggaaaa acgtatcgct gctattgaag
   196801 aggaaatgca ggctaacggc tctgactttg gtaagctggc tactctccaa aaagaattgg
   196861 atgagaaaaa tgaagcactc cttgaaaaat acgaacgcta tgagtatctc agtgaatttg
   196921 atagttaaga ctattcgaaa atcaaagtgc aaactatgtc ggcttcacat tgccgactca
   196981 agtacagcct gtgaccggct tcctaatttg cactttgatt tttattgagt ataaacgaat
   197041 agaaaaatcc cgtctcatga aaggatttct ctattctttt ttggtttctt gatgaaagat
   197101 attttgccag gtttcgtggc gacgccagat actggtatgg atgataccat ctaactcata
   197161 gcagataagt ttggtttttt gactgatgga agtaatttga atgtccttga tagcagaatt
   197221 taactctttt ttggtcttat aagcctcttt atccatctgc tctccatctt ggcgaatata
   197281 gacaaaatca tcagtcaaga gttcttctag ttggtttcct tggtcgatca attgttcacg
   197341 cataagcaat tttttataga cattgtctaa aatttcatcc tcagggatag gtgctggttc
   197401 gatatggaca tcggtatcaa agacgccaaa acgctcctcc agcatagact cgacctgatc
   197461 cgcgatttca tggctttcaa aaacagacaa gtcaggattc atctctagtg taatatccag
   197521 gtagatgttg ctaccgtagg tgcgacctct ttgcgatttg accttgctga ttttgggaat
   197581 ttccatgata gccttttggt agtcctcgag caggcggtcg tcaaagccat ctgaaagact
   197641 aaaggaagac tcgatgaaga tatcataggc agtcttcaag ataaagaaag tgatgatgat
   197701 agcaaccagt ttatccacaa tcggataatt gaaactacta gctaggatgg caatggcggt
   197761 tccaagtgag gtaacagcgt cagaaagatt gtccttagca gctgccttca gcgccttgga
   197821 gttggatttc ttactgaggc gagtattgta gagatagacc acaaacataa tcgctgcaga
   197881 aatgattcct agagttgcac caagaggatc aatgaccgtt tcttcccgac tgagaatctt
   197941 ttgaatggta tctcttagaa catcgaaacc gacatagaac atgatgatag aagtgatcaa
   198001 gcttgccaaa tcttcaatct tccaatgacc aaaacggtgg tcacggtctg caggctggcg
   198061 cgccatccga atcccgatta agagggccac atttccaatg atgtccgata cgttattaaa
   198121 accatcggcc accaaactgg atgaatgaag gagatgacca gttgctaatt tggctgcaga
   198181 caagatcaaa taggtcgaaa tactgataat ggctccacgc tcagctaact tgagatttga
   198241 gatagattgc ttcattcaac ttcctttcta gtcacatagc attctaccat tatactggtt
   198301 ttcaaggaaa aattcaaata aggcagtttt tactctttga aaactcccca aaatttggta
   198361 taatggtact actcaaggga gtagctggca gaaacctgtg atagtgtcgt cattccgaat
   198421 tttatgctga aaagtatgct ttccggccct atcttaaaca gcgagacttg ttatgattaa
   198481 caggtctctt tttgtttgtc gtgaaaagat atgacagaaa gagagtctgt tttgcacaca
   198541 atgtcaagga ggagacacat gtcaaaagaa caaaaacgcc aagcgtttta tactcagagc
   198601 cctgaagagg tcttgcaggc tgtggatgcg accgagcaag gtttgtcatc aagtgaggcg
   198661 gaaaagcgcc ttgccgaatt tgggcacaat gaactcgaag aaggcgagaa acgatcaatc
   198721 ttggtcaaat tcatcgagca atttaaggat ttgatgatta tcatcctagt tgcggcagca
   198781 atcttgtcag tcgtgacttc tggtggggaa gatatcgcag atgccattat catcctagct
   198841 gtggttatca tcaacgctgc ctttggtgtt taccaagaag gaaaagctga agaagctatt
   198901 gaagccctca aatccatgtc tagtccagtt gcccgcgttc ttcgtgatgg acacatggca
   198961 gagattgact ctaaagaatt ggtaccaggc gatatcgttg cccttgaagc aggtgacgtg
   199021 gtaccagcgg acctacgttt gatagaagcc aactctctta aaattgaaga agcagccttg
   199081 acaggtgaat ctgtaccagt cgaaaaagac ttgtcagtcg agcttgcgac agatgctggt
   199141 attggtgacc gtgtcaacat ggccttccaa aactcaaacg taacctatgg tcgtgggatg
   199201 ggtgttgttg tcaatacagg tatgtacact gaagttggtc atattgctgg tatgcttcaa
   199261 gatgcggatg agactgatac accactcaaa caaaacttga acaacctttc taaggtcttg
   199321 acctatgcta tcttggtcat tgcccttgtt acttttgtag tgggtgtctt cattcaaggg
   199381 aaaaatccac ttggtgagtt gttgacttct gttgcccttg ccgttgcagc cattccagaa
   199441 ggacttcctg ctatcgttac catcgttctt tctcttggta ctcaagtttt ggccaaacga
   199501 cattccatcg ttcgtaagtt gccagcagtt gaaacacttg gttcaactga aatcatcgct
   199561 tctgataaga ctggtacgct gactatgaac aagatgacag tcgaaaaagt cttctacgat
   199621 gcggttctac atgactcagc tgatgatatt gaactaggtc ttgaaatgcc actacttcgt
   199681 tcagttgtct tggccaatga tacgaaaatc gatgtggaag gtaacttgat tggtgaccca
   199741 accgaaacag cctttatcca atatgccttg gacaagggct atgatgtcaa aggtttctta
   199801 gagaaatatc ctcgtgtagc tgaattgcca tttgactctg accgtaagct catgtcaaca
   199861 gttcacccat tgccagatgg tcgtttcctt gtagcagtca agggtgcgcc agaccaactc
   199921 ttaaaacgtt gtcttcttcg tgataaggct ggggatattg ctccgattga tgagaaggtt
   199981 acaaatctca ttcatacaaa caattctgaa atggctcatc aagccttgcg tgtccttgca
   200041 ggtgcttata agattatcga tagtattcca gaaaatctca cttctgaaga gcttgaaaat
   200101 gatttaattt ttactggttt gattgggatg attgaccctg aacgtcctga agccgctgag
   200161 gctgttcgtg tggctaagga agcgggaatc cgtccaatta tgattacagg tgaccaccaa
   200221 gacacagcgg aagccattgc caaacgtttg ggaatcattg acgcaaacga tacagaaggt
   200281 cacgttttaa ctggtgctga actcaatgaa ctgtcagatg aagaatttga aaaagtcgtt
   200341 ggtcaatact ctgtttatgc ccgtgtgtct ccagaacaca aggttcgtat cgtcaaggct
   200401 tggcaaaaac aaggtaaagt cgttgccatg acaggtgacg gtgtcaatga cgcgccagct
   200461 ctgaaaacag ccgatatcgg tatcggtatg ggaatcactg gtacagaggt ttctaagggg
   200521 gcttctgaca tgattcttgc agatgataac tttgcgacta ttatcgtcgc agtggaagaa
   200581 ggacgtaagg tcttctcaaa cattcaaaag actattcagt acctactttc tgctaatact
   200641 gctgaagtat taaccatctt cctatcaacc ttgtttggtt gggatgtctt gcagccggtt
   200701 catcttttgt ggatcaactt ggtaacggat accttcccag ctatcgctct tggtgttgaa
   200761 cccgcggagc ctggtgtcat gaatcataaa ccacgtggac gcaaggcaag cttcttctca
   200821 ggtggtgttt tgagttctat catttatcaa ggtgtactcc aagcagctct tgttatgagt
   200881 gtttatggcc ttgcgattgc ttacccagtt catgtgggtg acaatcatgc tattcatgca
   200941 gatgccctaa cgatggcctt tgcaaccctt ggtttgattc agctcttcca tgcctacaat
   201001 gtcaagtctg tctaccaatc catcttgaca gttggcccat tcaagtctaa gacctttaac
   201061 tggtccatct tggtatcctt tatccttctc atggcaacaa tcgttgtaga accgcttgaa
   201121 ggaatcttcc acgtaaccaa actagacttg tcacaatggg gaattgttat ggctggaagc
   201181 ttctcaatga ttatcatcgt cgaaatcgtt aagtttattc aacgcaaact cggttttgac
   201241 aagaatgcga tttaagggag gtttcggatg tcagcatatc aattaccgac cgtatggcag
   201301 gatgaagcta gtaatcaagg agcttttacg gggctaaaca gacaaacagc aggtgcccgt
   201361 ttcgaacaaa acttgccaaa aggagaacaa gcttttcagc tttattcact gggaacacca
   201421 aatggtgtga aggttactat cttattggaa gaattactag aagctggttt taaggaagcg
   201481 gcttacgact tgtataagat tgctatcatg gatggggatc aattcggatc agactttgtg
   201541 aagctcaatc caaattccaa gattccagcc ttattggacc agtcaggtac tgaagatgta
   201601 agagtctttg agtctgctca tattcttctt taccttgctg agaaatttgg agccttttta
   201661 ccaagtaatc ctgtggaaaa ggtagaagtt ttgaattggc tattctggca agcaggtgca
   201721 gcaccttttc taggtggggg atttggacat ttcttcaatt atgctcctga aaaattggaa
   201781 tatcctatta accgttttac gatggaagtg aaacgccagt tggatttatt ggataaggaa
   201841 ttggctcaga aaccttatat tgcaggcaat gactatacga ttgcagatat tgctatctgg
   201901 tcttggtatg gacagttagt tcaagaaaat ctttaccaag gttctgcaaa attcttggat
   201961 gcctcaagtt atcaaaatct agtaaaatgg gcagaaaaaa ttgccaatcg tccagctgtt
   202021 aagcgtggct tggaagtaac ttatacagaa attaaatagc aaaaaagtca tcttcggatg
   202081 gctttttgct acagttgagg gaaagggttt gcagttatcg gcttttgtgc tataattgct
   202141 ataatatagt aaaaagcaag aggagtgtga ggaagtggaa aagaaaattg tgaaggataa
   202201 cttattttta tctcaagtgt ctcagccggc aagtcaggag gacctttatc ttgccagaga
   202261 tttgcaggat acactcttag caaatcgtga tacctgtgtt ggtctagctg ccaatatgat
   202321 tggggtgcag aagcgcgtga ttatctttaa tcttggcttg gttcccgtgg tcatgtttaa
   202381 cccagtgctt ctgtcctttg aaggatctta tgaggcagaa gaaggctgtt tgtccttggt
   202441 aggtgtgaga tcaactaagc gttatgaaac cataaggctt gcctatcgtg acagcaagtg
   202501 gcaggaacag accattacct tgacaggctt cccagctcag atttgccagc atgagctgga
   202561 tcacttggaa ggacgaatca tttaggagga aagcaaatga aacgaatagt ctttgaactt
   202621 atttttatcg caacgacctg gtatatcttt ttaccgcccc ttaacctgac cagctgggaa
   202681 tttctcttct tcctctgtgg gcatttgtta gttgtggcaa tcttatttgg ctttggcaag
   202741 gggataaacc ttgtcaaaac ggttcatgtg cgccacggta aggcggaagc tgccttaaat
   202801 cttgagggtt tcaaaatcaa tcggttaggg aaaattctgt tagcttcgat tggaggaatt
   202861 cttctcttgg cagctttggt ttccttggta acttccagca tgtttcaggc taaaaattat
   202921 gccaatgtag tcacggttac ggaaaaagac tttactgaat ttcctaggag tgacaccagt
   202981 aaggttccta tcctagatag aagtactgct gaaaaaattg gagaccgcta cttgggttcc
   203041 ctaaccgata aggtgtcgca atacgtagcg gcagatacct atacccaatt gacaattgat
   203101 gggaaacctt atcgggtcac accactagaa tatgcagacc ctatcaaatg gtttaacaat
   203161 caagccaagg gaatcggtga gtatatcaag gtggacatgg taactggaaa tgcggatttg
   203221 gtggacttga agacaccaat caagtattca gactcggagt attttaaccg tgatgtcaaa
   203281 cgtcacctgc gcttgaagta cccgaccaaa atctttaaaa ctccatcttt tgaggtggac
   203341 gatgagggca atcctttcta tgtagcaacg gtttaccaaa agcaatttgg acttgctgtt
   203401 cctcgtcctg cttcagtcat tatcttggat gctacaaatg gagaaaccaa ggaatacagc
   203461 ttatcagatg ttccagaatg ggtggacagg atctatccag cagaggaaac cattgagcaa
   203521 attaactaca acggcaagta caaggacggt ttcttgaatg ccatgatttc caagaaaaac
   203581 gtgacccaga ctaccaaggg ctataattac ttgtctatcg gtaatgacat ctatctctac
   203641 acaggtgtga cgtcggctaa tgcggatgag agtaatcttg gtttcatcct tgaaaatatg
   203701 cgaacaggag aaatcactaa gtatagcttg gcttctgcga cagaagaatc agcccgtgaa
   203761 tcagcagaag gtgctgttca ggagaaatcc tacaaagcaa ccttcccaat cctcatcaac
   203821 ctcaatgaca agcctctcta catcatgggc ttgaaggaca atgctggctt ggtcaaagag
   203881 tacgccctgg tagacgcagt cgagtaccaa aatgttatcg ttgctactac agtggaagag
   203941 atgctcagca agtatgccaa taaaaacgac cttgaaattg acaatgcaac gacagaaagc
   204001 atcaatggag tagtagcaga cctcaaatca gctgttatca agggagacac tgtctacttc
   204061 tttaaagttg atggcaagat atacaaggtc aaggcttcag tatccgatga ccttccttac
   204121 cttgaaaatg gtaaaacctt cgaaggtcaa gtaggaaaag acaattatct caagaccttt
   204181 aagctacggt aaaaataggt ttttttcaga aagtatatgt tataataagg taaattaagc
   204241 ctaatggagg acaaagaaat gggtttttat ttgatggttg cttcaatgct actcggactg
   204301 ctcgctttga agataggttt ttctcagttc aaggagaaaa aagataaatt cttatctatc
   204361 ttaacaagtt tagctggcac agcccttgtt ctcgtggctg tctggttagg atggcccaaa
   204421 taaatagaaa aacctcggtc aaaccgaggt ttttcaaatg aatttcttgg ttgtggctaa
   204481 aaaatatgct acactatcaa tatgaaaatt ttaatcccaa cagcaaaaga aatgaacaca
   204541 gacttgccaa gtatcgaggc aattccttta aaaccagaaa gtcagaccgt gcttgatgcc
   204601 ttggctctct attctgccag tcaattggag agtttctaca aggtatcagc tgagaaagcg
   204661 gcggaagaat ttcaaaatat ccaagctttg aaaaggcaaa ctgctcaaca ctatccagcc
   204721 ttgaaacttt ttgatgggct tatgtaccgc aacattaaga gagataagct gaccgaggcg
   204781 gaacaagatt atcttgaaaa tcatgtcttc attacctcgg ctttgtacgg tgttgttcca
   204841 gccttgtcac ccatggctcc tcaccgtttg gattttttga tgaaattaaa agtcgctggt
   204901 aagactttga agagccattg gaaggcagtc tatgatgaag ctctgaagaa ggaagaagtg
   204961 attttctctc tcttgtcatc agagtttgag actgtatttt ctaaggaaat cagagcaaag
   205021 atggtgacct tcaaattcat ggaggataga ggcggtcagc tgaagattca ctcaactatc
   205081 tccaagaaag cgcgcggggc ctttctaaca gctttaatag aaaatcaagt acaaactgtg
   205141 ggggaagcac gtcgcttgaa ctttgctgga tttgtttacc gagaagattt gtcacaacca
   205201 cagggattgg tttttgtaaa ggaagtatag aaatcagata ttttgtattt ggcaatatgt
   205261 atcatcagct gttttagttt ataaatgaga aaaaaagcga acaagctagt cttctgagtg
   205321 tcagaaaagt agtcttgttc gcttttatta tgttatactc ttcgaaaatc tcttcaagcc
   205381 acgtcagcgt cgccttaccg tatatatgtc actgacttcg tcagttctat ctacaacctc
   205441 aaagcagtgc tttgagcagc ttgcggctag cttcctagtt tgctttttga tttttattga
   205501 gtgttagtta cttgatagct tcgaccaagt cttgagcttg tttttcaagt gagtttagga
   205561 ctgtttcttc aagaaccaat tttccgtctg cccaggcaga gtcattaaca cgtgcagcag
   205621 tgaaatcacc aacgccttgt gtacggataa atggcaagag gtctttgtag atagcgaaaa
   205681 gttgatcgtg ccctgcattg gctacagatg atactgtgac aaacttgtct tgaagggcag
   205741 aaacgccacg tgtatcagac aagtcaaggg cacgagatag ccagtcaagc aagtttttca
   205801 ctgtaccagg gatagagaag ttgtagactg gagagaaaat ccagatagca tccgcaacga
   205861 gaactgcttc acgagcggca gctacagctg gatgtgttgg gacttccaaa tcttggctga
   205921 agagagggag ggctgaataa tcaaggtagc taacttccgc tttactagca agtgctttct
   205981 cagcttcgag cgccatttgg tggttgaaag aaccttgacg tagtgatccg acgataaata
   206041 atactttttt agacatgatg tgtctccttt ttcttaaaat ttcgagaact ctctcgttgt
   206101 tataaaatat attacaacaa aacaaaagaa cttgcaagaa atttgctcag agtttatttg
   206161 aaaattgtaa aatttcggaa actctagtca tttgtgactg aaaaagtaag aactgtttca
   206221 ctttcaaaat cggttttgtt tgaagggaga aatagaattg gttgctcaaa gcacagcttt
   206281 gaggttgcag ataaagctga cgtggtttga agagattttc gaagagtatt cttatattca
   206341 cttgtaataa agcttaatag atggtaaaat agacgagtga aaaaaagaca aaacaaagca
   206401 aaaaataatc tactgtggca gtatggtcta gggatgacga ttttgtttgt ggttatcagt
   206461 ggttcctttc tgtatatggt ttctcttagc atgaaaccct atcaaacagc taaaagtgaa
   206521 ggagaaaaat tagctcagca gtatgcagga ttagagcagg tcgatcaggt tgatttatac
   206581 aatggcttgg aatcttatta cagcgttctt ggtcgtaata aacagcaaga agcgcttgct
   206641 gtcctgattg gtaaagatga tcataagatt tacgtttatc agctaaatca gggtgtttca
   206701 caagaaaaag cagaaacggt ttctaaggaa aagggagctg gcgaaattga caagattatc
   206761 tttggtcgtt atcaagataa gccaatctgg gaagtcaagt caggatctga tttttatcta
   206821 gtagattttg aaacaggagc attggtcaac aaggagggcc tatggaatta tccaaccgtg
   206881 ttttagaaat ggaagaaagt gtgactttgg ctgctggagc ccgtgccaaa gcactgaagg
   206941 ctgagggtag agatattttg tctctaacct tgggtgagcc agatttcact actcccaaaa
   207001 atatccaaga tgccgccatt gcatcgattc gagatgggcg tgcttctttt tatacagtaa
   207061 cctcaggtct gccagagctt aaggcggcgg tcaatagcta ctttgagcgc ttttacggct
   207121 attctgtagc gtcaaatcaa gtgacagtcg ctgcgggagc caaatattct ctctatacct
   207181 tctttatggc tgtggtcaat ccaggtgatg aagtcatcat cccaacccca tactgggtta
   207241 gctatggaga tcaggtcaag atggcagaag gcgttcccgt ctttgtttct gctaaggaag
   207301 acaatcactt taaggtgacc gtagagcagt tagaagcagc tcgcactgac aagaccaagg
   207361 ttttggtgct gaattcgcca tctaatccca caggtatgat ttacacccgt gaggaactct
   207421 tggcaattgg aaactgggct gtagaaaatg atattctcat cctagcagat gatatctatg
   207481 gccgcttggt ttataatggt catgagttca caccgatttc tagcctatcg gaagcgattc
   207541 gcaagcaaac agtggtcatc aatggtgtgt ctaaaaccta tgccatgact ggttggcgga
   207601 ttggttatgc cgttggagaa gcagacatta tcgctgccat gtccaagatt gcaggtcaaa
   207661 caacttcgaa tccgtcagca gtagcccaat atgcagcagt tgaggctcta tcaggtgagc
   207721 aagatactgt agaaagcatg cgtcaggcct ttgaggaacg tcttaatacc atctatcccc
   207781 tccttgcaga agtgccagga tttgaagtgg tcaaaccgca aggggccttc tatctcttcc
   207841 caaatgtcaa aaaggccatg gagatgaaag gctacacgga tgtgacagac tttacaactg
   207901 ttatcttaga agaagccgaa gtggccttgg taacaggagc tggatttgga gcaccagaaa
   207961 atgtccgcct cagctatgcg acagacctag acacgcttaa agaagcagtc gaacgcttga
   208021 aagcatttat gggtagtgag aatgattgat cattttgaga ttaaggtaaa ggatttacaa
   208081 atttcagaag gattttatag gagttttctc gctcctttgg actataaatt ggcttttaag
   208141 actagttctc taattagttt tctatccccg aacagccctc atcctggtgg tgatttttgg
   208201 ctgactcagg gaacacaaga tcctgttcat tttgcttttt tagcagaaaa taaggaagaa
   208261 gttcaggctt gttatgaggc tggcttagag gcaggtgggc gagacaatgg ggctcctggt
   208321 tatcgaagtg agcatccgat ttactatgct gcttttgtga ttgacctgga tgggaacaat
   208381 atagaggtgg tttgccataa agaataaaaa agaaaaggaa aaataatgac aaaacgtgta
   208441 acgattattg acgtaaaaga ctatgttggt caggaagtga cgattggcgc ttgggttgcc
   208501 aacaaatcag gaaaagggaa aatcgctttc ttacaattgc gtgatggaac agccttcttt
   208561 caaggtgtgg cttttaaacc aaactttgtc gaaaaatttg gtgaagaagt gggacttgag
   208621 aagtttgatg ttatcaaacg cttgagccaa gaaacgtctg tttatgtgac aggtattgtc
   208681 aaagaggacg aacgttctaa atttggctat gagttggaca tcacagacat cgaagtgatc
   208741 ggtgaatctc aagactaccc aatcacacca aaagaacacg gaacagactt tttgatggat
   208801 aaccgtcact tgtggctacg ctctcgtaag caagtagctg tgttgcaaat ccgtaacgct
   208861 attatctatg caacttatga gttctttgac aagaacggtt ttatgaagtt tgacagccca
   208921 attctttcag gaaatgcggc agaagattct acagaactct ttgaaactga ctacttcgga
   208981 acgccagcct acttgagcca atcaggtcaa ctttacctag aagcaggggc tatggctctt
   209041 ggtcgtgtct ttgactttgg tccagttttc cgtgctgaaa aatcaaaaac acgccgtcac
   209101 ttgactgagt tctggatgat ggatgctgag tactcatact tgacacatga tgagtcgctt
   209161 gacttgcaag aagcttatgt gaaagctctt ctacaaggtg ttcttgaccg cgcgcctcaa
   209221 gccttggaaa ccttggaacg tgatacagaa ctcttgaaac gctacattgc agagccattc
   209281 aaacgtatca cttacgatca agccattgac ctcttgcaag agcatgaaaa tgatgaagat
   209341 gctgactacg agcatcttga gcatggtgat gactttgggt caccacacga aacttggatt
   209401 tcaaaccact ttggtgtgcc aacatttgtc atgaactatc cagcagccat caaggccttc
   209461 tacatgaaac cagttcctgg aaatccagag cgcgtgcttt gtgcagactt gcttgctcca
   209521 gaaggctatg gagaaattat cggtgggtct atgcgtgagg aagattacga tgcccttgtc
   209581 gctaagatgg atgaacttgg catggatcgt acagaatatg aattctacct tgaccttcgt
   209641 aaatacggta cagttccaca cggaggattt ggtatcggta tcgaacgtat ggtaaccttc
   209701 gcagcaggaa caaaacatat ccgtgaagct attccattcc cacgtatgtt gcaccgtatc
   209761 aaaccataag aacaggaaaa cgcccatgtg gcgttttttc gaattctagt gtttttactt
   209821 gcgtaaaaaa attttttcta gtataatagt ttattgtgag cgaacctcac ttaccccttg
   209881 caaagtcttg gggtcattag accaaaagga ggaacatatc aatggctaaa tacgaaattc
   209941 tttatatcat tcgtccaaac attgaagaag aagctaaaaa cgctttggta gcacgttttg
   210001 actctatttt gactgacaac ggtgcaactg ttgttgaatc aaaaacttgg gaaaaacgtc
   210061 gtcttgcata cgaaatccaa gatttccgtg aaggacttta ccacatcgtt aacgttgaag
   210121 caaatgacga tgcagctctt aaagagtttg accgtctttc aaaaatcaac gctgacattc
   210181 ttcgtcacat gatcgtcaaa attgacgcgt aagaaggtaa actatgatta acaatgttgt
   210241 acttgtaggg cgtatgacac gtgacgctga gttgcgttat accccatcaa atgtagcagt
   210301 tgcgactttt actcttgcag taaaccgtac atttaagagt caaaatggtg aacgtgaggc
   210361 tgattttatc aatgtcgtta tgtggcgcca acaggctgaa aatcttgcta actgggctaa
   210421 aaaaggctca cttatcgggg tgacaggtcg tatccagact cgtagttacg ataaccagca
   210481 aggacaacgt gtctacgtga cagaggtcgt ggctgagaat ttccaaatgt tggaaagccg
   210541 tagtgtgcgt gagggccaca caggtggagc ttactctgca ccaactgcaa actattcagc
   210601 acctacaaat tcagtaccag acttttcacg taatgaaaat ccatttggag caacaaaccc
   210661 attggatatt tcagatgatg atttaccatt ctaatggaca actaaactta taaaggagaa
   210721 aaaacatggc tcaacaacgt cgtggcggat tcaaacgccg taaaaaagtt gattacatcg
   210781 cagcaaacaa aattgaatat gttgattaca aagatactga gcttcttagc cgtttcgttt
   210841 cagaacgtgg gaaaatcctt cctcgtcgtg taacaggaac ttcagctaaa aaccaacgta
   210901 aagtaacaac agctatcaaa cgcgctcgcg taatggcttt gatgcctttc gtaaacgaag
   210961 attaaagaaa agacccggtt gggtctcttt ttcatgagct tgaaaacaag aaagcgaatt
   211021 aagaccccaa cgggtctttt ttcacaagct ttgaaatgag agagcgagtt aggctcagtg
   211081 gctccctttt tacgagtttg aaaacaagag aacacattaa aagcacgatg gagctttttc
   211141 ataaatatgt cttttttctc atccaagaaa ttaaaataaa aatgataaac tttttgaaaa
   211201 taggggattt gcctacttta tgatataatg gaaagagtta gattgaaaga ggtagtgaga
   211261 tggacgcgaa attaagatac aaggcaaaga agatcaagat tgtctttttt gatattgatg
   211321 atacattgcg gaattcaaag acagggttta ttccaactac aattcccact gtttttaaac
   211381 agttgcgtga aaaaggaatt ttaacaggaa tcgcctctgg acgtggcatt tttggtgttg
   211441 ttccagagat tcgtgatctc aagcctgact tttttgtaac tttgaatgga gcttatatcg
   211501 aagataaaaa aggtcaggtc atttatcagc atcagattga aaagtcagat gttgaggagt
   211561 atatctcttg ggctaagcaa gaaggaattg aatatggctt ggttgggagt catgatgcca
   211621 agttgtcgac tcgcaccgat atgatgagtg aagctatcaa tccaatttat cccgacttag
   211681 atgtagatcc cgatttccat gaaaaagaag atatctatca gatgtggact tttgaagata
   211741 agggagatga cttgcacttg cctgacagtc tctcagacaa acttcgcatg gttcgttggc
   211801 atcaacattc gtctgatatt gtgccgattt caggctccaa agcgacgggg gtggaaaagg
   211861 ttgtggaaca ccttggcttg aaaccagaga aggtcatggt ttttggagat ggtctcaacg
   211921 acttggaact ctttgattat gctggaatca gcgttgccat gggaatttct catgataaaa
   211981 tcaaagaaaa agcagattat attacaaaaa cattagaaga agatggcatt tttgatgcct
   212041 tagaagtatt tggtatggta gaaaaagaat tgcattttcc acaagtagac attgaaacag
   212101 tagaaggtcc tcttgcgact attaagacca atcacggaga cttacgtatc aagcttttcc
   212161 ctgaacatgc tcctaaaaca gtggctaact ttgtatctct ttcaaaagat ggctactatg
   212221 atggtgtcat tttccaccgt attatcaagg actttatgat ccaaggtgga gacccaactg
   212281 gaactggtat gggtggcgag tcaatctacg gcgaatcttt tgaggatgaa ttctcagaag
   212341 agctttacaa tatccgtggt gctctttcca tggcaaatgc tggtccaaat accaacggca
   212401 gccagttctt tatcgtgcaa aaccaacacc taccttattc gaagaaagaa attactcgtg
   212461 gtggttggcc agaaccgatt gcagaaatct atgccaatca aggtgggaca cctcacctag
   212521 accgccgtca cacggttttt ggtcagttag ctgatgaagc atcttacgct gtcttggatg
   212581 ccattgctgc tgttgagaca ggagctatgg acaagccagt tgaagatgtt gtaattgaaa
   212641 ctattgaaat cgaggactaa gatgaaaatc ggtgataagc taaaggggcg tattacaggg
   212701 attcagccct acggtgcctt tgttgagtta gagacgggtg atacggggct gattcacatt
   212761 tcagaaattc ggacaggatt tattgaaaat attcatgaaa ccttgaaagt cgatgaagag
   212821 gttcaagttc aggtagtgga tttagatgaa tttacgggga aagccagtct ttctatccgc
   212881 actttggagg aagaaaagta ccagtttcct agacggagac gcttttcaag cgaccgcttt
   212941 aactacggtt ttgctccctt tcgacgaatg ctaccaatct ggactggaga agccctgcac
   213001 catttaaaaa agaagaagta gtttagagtt ttatattttt tgtaatgtta atatgaattt
   213061 gctataatag gaccatggaa gaagaacaat tattaaaatc aggagagcgc attaaccagc
   213121 tcttttcgac agatatcaaa atcattcaaa atagagaggt ttttagctat tcggtggata
   213181 gtgttctctt atcacgattt ccacgttttc ctaagaaggg gttgattgtg gatttctgtg
   213241 ctgggaatgg agcagtgggg ctttttgcta gcactcgtac tcaagcacag atattgtctg
   213301 ttgagattca ggagcgtttg gcggatatgg ctgaacgctc tgtccgtttg aatggattag
   213361 aggagcaaat gcaggtcatc tgcgatgatt tgaaaaatat gcctgctcac attcagggga
   213421 gtaaggtgga tatgattttg tgtaatccac cctatttcaa ggtgaatcct tattctaatc
   213481 tgaacgagag tgaacattat ctcttggctc gacacgaaat cacgactaat ttggaagaaa
   213541 tctgtcgtag tgcccagagt attctcaagt ctaatgggcg tttggccatg gttcatcgtc
   213601 ctgatcgact tctggatatt ttggatacgt taaaacgaca taatctagcc cctaagcgcc
   213661 tgcagtttgt ttatccaaaa agagaaaagg aagccaatat gcttttgatt gaggcgatca
   213721 aggatggctc aacaagtggc tttaaggtct tacctccttt gattgtccac aatgatgatg
   213781 gctcttatac gcccgaaatc gaagagattt attatggatc ataaggctta tatgtacgtt
   213841 ctggagtgtc gtgatggatc ctactatata ggctatacga ctgatatgag aagacgcctc
   213901 gctatccaca atagtgggaa gggagccaaa tatacacgag cacgcttgcc agtcaaactt
   213961 atctatgctc aaggttttgc cagtaaggaa gaagccatgt cggctgaagc tcttctcaag
   214021 cgtaagaaga ggccacagaa ggaagaattt ttatctgaaa atcaagatag aaatttactc
   214081 agttattttg aagaatcgtg gggagtcctt tgactcctct tacctttgtc aaaaagcgaa
   214141 aaaaatgcta caataaagaa aataaacaaa atgaggtatt atcatgtcca agattctagt
   214201 atttggtcac caaaatccag actcagatgc catcggatca tctgtagctt ttgcctacct
   214261 tgcaaaagaa gcttacggtt tggatacgga agctgttgcc cttggaactc caaatgaaga
   214321 aacagccttt gtcttgaact attttggtgt ggaagcacca cgtgttatca cttctgccaa
   214381 agcagagggg gcagagcaag ttatcttgac tgaccacaat gaattccaac aatctgtatc
   214441 agatatcgct gaagtagaag tttacggtgt tgtagaccac caccgtgtgg ctaactttga
   214501 aactgcaagc ccactttaca tgcgtttgga gccagttgga tcagcgtctt caatcgttta
   214561 ccgtatgttc aaagaacatg gtgtagctgt gcctaaagag attgcaggtt tgatgctttc
   214621 aggtttgatt tcagataccc ttcttttgaa atcaccaaca acacacccaa cagataaaat
   214681 cattgctcct gaattggctg aattggctgg tgtgaacttg gaagaatatg gtttggcaat
   214741 gttgaaagct ggtaccaact tggctagcaa atctgctgaa gaattgattg atatcgatgc
   214801 taagactttt gaactcaacg gaaataatgt ccgtgttgcc caagtgaaca cagttgacat
   214861 cgctgaagtt ttggaacgcc aagcagaaat tgaagctgca atgcaagctg ccaacgaatc
   214921 aaacggctac tctgactttg tcttgatgat tacagatatc gtcaactcaa actcagaaat
   214981 cttggctctt ggtgccaata tggacaaggt cgaagcggct ttcaacttca aacttgaaaa
   215041 caatcatgcc ttccttgctg gtgccgtttc acgtaagaaa caagtggtac ctcaattgac
   215101 tgaaagcttt aatgcgtaag attttgggtg tcagctcaaa atcggaaagt ctagtttgcc
   215161 ttatatcgaa aggagtttcg gctccttttt tctaggagtg aagtatgtta gaaaatggcg
   215221 atttgatttt tgtgagagat gggtcagaca tgggacaggc catccagact tccacaggta
   215281 actatagcca tgttgccatt tatttggatg ggatgattta tcatgctagt ggacaggctg
   215341 gtgttgtctg tcaagaaccg gcagacttct ttgagtccaa tcatttatac gacctctatg
   215401 tttacccaga aatggatatc cagtcggtga aggaaagagc ttgcaaacat cttggagcac
   215461 cctacaatgc ttctttctat ccagatgcac ctggtttcta ctgctcccag tatatagcag
   215521 aaatcctacc tatttttgaa actattccta tgaaatttgg agatggggag caggagatta
   215581 gtgatttttg gagggagtat tacatagaac taggtctgcc tgttcctctg aaccaagctg
   215641 gtaccaatcc tagtcagttg gcagcatcgc ctctgttaca atgtaaagaa aggaatcttc
   215701 atgattcaga tttttaatcc atctcgtttg acgagacagc catttttgga gaattgatcc
   215761 gctatctgga ccagtatgag gatgtgattc tacgggaaat taaggctcaa tttccagatg
   215821 ttgcagttga taaactcatg gaagagtata taaaggcagg cttgattcta cgtgaaaata
   215881 agcgctatta cctcaatttt cctacgcttg aatcacttga tagtcttgaa ctggatcaag
   215941 agatttttgt cagagaagct agtccggtct atcaagcctt gttggagcag agttttgaga
   216001 cggaattgcg caatcaaatc aatgcagcta ttttagttga aaagacggac tttgcgcgca
   216061 ttaaaatgac tctgtccaat tatttttaca aggtcaaaca gcagtatcct ttgacagaaa
   216121 aacagcagga gctctatgac attttaggag atgttaatcc tgagtatgca ctcaagtata
   216181 tgacggcttt tttgttgaaa tttctcaaaa aagaccagct tatgcagaaa tgccgtgata
   216241 tctttgtgga cagtttggtt gtcttaggct atattgtgca aaatgaagat ggaaagtatg
   216301 agttggctat cgattttgat aaggagagat taactttcta cttagcgtga tttcttgttt
   216361 ctgagtacat tgtttgactt tccttagtat tcggtataaa ctatatgtaa ccggtaacac
   216421 atatcggaat aaactaaagg agacaatcat atgtcacttg aaaacaaatt ggaacaagca
   216481 acaggcgctg tcaaagaagg ttttggtaaa gttactggag acagcaagac agaacttgaa
   216541 ggagctgttg aaaaaacagt tgctaaggca aaagacgttg tagaagacgc aaaaggtgct
   216601 gtagaaggtg ccgttgaagg tttgaaaaac gtttttacta aagaatagga aaaaatcaag
   216661 ggtttcattt tcccttgatt ttttctattc ttataaataa ttttctgcga cggctgtatc
   216721 tcctgggtag gattctttct tgccctggat gatttggtaa caatcggctc ccttacccgc
   216781 aataataact gcatctaatt cgtgatttgt gatagccatt gccgccttga tggcttcttg
   216841 gcgatccgca atcttctcaa caggatgatt gatgtagcta ctaatttcat ctgcaatggc
   216901 cattgggtct tcatagttag ggtcatcagc agtcagaaag acttgaatct cagggtgttg
   216961 attgaggagg aggccaaagt ccttacgacg actttctccc ttgtttcctg ttgatcccag
   217021 aaccagagca atctttccgg tttgatgagt ttcaaccaca ttgatgagtt ttttcagact
   217081 atccccattg tgggcatagt cgatgaagac cttggctcca tttttctgag tgaggacttc
   217141 catacgacca ggaacgcggg ttgcagcgat gccttttttg atgtcctcaa gacttgctcc
   217201 gagacggaga caagcaagtc cagcagcaac tgcattttct tggttgaagt tgccaatgag
   217261 ttggatatca taatctccag cgagtttacc cgtagctgaa aagctaaagg ctttggaatt
   217321 ctcgatttgg ttatcaaatt ggctaccata gaaatcatgg tcttgatctt caacctgttc
   217381 tttcaagact gagaagtggt ccatgtcact gttaatgatg actgctcggc tattttccat
   217441 caagagacgc ttgtggtaga aatagtcttc aaagctaggg tgttcaatcg ggccgatatg
   217501 gtctgggctg atattgagga aaactcccac atcaaaggtt agaccataga cacgtctgac
   217561 cagataggat tgactggaga cttccatgat gaggtgggta cggtcatttt gcacagcctg
   217621 attcatcatg tcaaagaggt caatactctc aggggttgtc aacgctgact taaagaaagt
   217681 ctcgccatca agagttgtgt tcatggtcga caacatagca ggtcgatgcc cttgagataa
   217741 gatgttatag gcgaaatagg ctgctgttgt cttaccctta gtaccagtaa aggcaaggag
   217801 tttgagtttt tcctgtggat taccatagaa ctccatggca atcaaactca tggctttctt
   217861 tatatcgttc acaatgatga cagggatacc gacttcgtag tccttttcag ctacatacca
   217921 agctaagcct tgtgttatag cagaaagaag gtattctttt ttaaaggcag cgccttttgc
   217981 aaaaaaaaga gtgtcttctg ttacttttcg gctatcgtag ctgatgctat caaaaacaac
   218041 tttgctgtag ttgtagtggt aatgaccttg gtcaataatt tcgcgaaaaa ggccatcttt
   218101 ctttaaaata tctaatacag tttcaatttt tatcatactt tctattgtaa accgaaagtc
   218161 gcaaatttac aagtaacaag gaaaagttta taatggaaga taaggagttt ttcctagtta
   218221 tcaaaattga atgaggaatc tatgtcgcac gaaaacaatc accagcaggc ccagatgtta
   218281 cgggggactg cttggctaac ggctagtaac tttatcagtc gcctactcgg ggctgtttac
   218341 attatccctt ggtacatctg gatgggggct tatgcagcta aggcaaatgg tctctttacc
   218401 atgggttaca atatctatgc ttggttcttg ttggtttcaa cagcggggat tccagttgcg
   218461 gtggccaagc aagttgccaa gtataatacc atgcgagaag aagaggatag ctttgccctg
   218521 attcggagct tcttaggctt tatgacagga ctaggcctgg tttttgcttt agtcttgtat
   218581 gtctttgctc cttggctagc agacttgtct ggcgtgggca aagacttgat cccaatcatg
   218641 caaagcttgg cttggggagt cttgattttc ccgtctatga gtgttatccg aggatttttc
   218701 caagggatga ataacctcaa accttatgcc atgagccaaa ttgctgagca ggtcattcgt
   218761 gttatctgga tgctcctagc aacctttatc attatgaagc tcggttcagg agattatcta
   218821 gcagccgtta cccaatcaac ctttgctgcc tttgtcggta tggtagccag ttttgcagtc
   218881 ttgatttatt tccttgccca agaaggttca ctcaaaagag tctttgaaac aggagataag
   218941 attaacagta agcgtctctt ggttgatacc attaaggaag ccattccttt tatcctgaca
   219001 gggtctgcca tccagctctt ccagattttg gatcagctga cctttatcaa tagtatgagc
   219061 tggtttacca actacagcaa tgaggacttg gttgtcatgt tttcttattt ctcagccaat
   219121 cctaataaaa tcacgatgat tttgatttct gtaggggttt cgattgggag tgttggtttg
   219181 ccacttttga cggaaaacta tgtcaagggg gacttgaaag cagcttctcg tctggttcag
   219241 gacagtctca ccctactctt tatgttcttg ctaccagcaa cggttggagt ggttatggta
   219301 ggagaacctc tatatacagt cttctatggt aagccagata gtttggctct gggcttattt
   219361 gtctttgcag ttttgcagtc tattatttta ggcttgtaca tggtcttgtc tccaatgctt
   219421 caggccatgt tccgcaaccg caaggccgtt ctctatttta tctatggttc tattgccaag
   219481 ctagtcttgc aactacctac catcgccctc ttccacagtt atggtccttt gatttcaaca
   219541 accattgctc tcatcattcc taacgtcttg atgtatcggg atatttgtaa agtaactggt
   219601 gtcaagcgca aggtgatttt gaagcgaacc attttaatca gtttgctgac cctagtcatg
   219661 tttctgttaa taggaaccat ccagtggctg ttaggatttt tcttccaacc aagtggacgt
   219721 ttgtggagct tcttttatgt agctcttgtc ggtgccatgg ggggtggact ttatatggtt
   219781 atgagtctgc gtacctattt attagataag gtaataggaa aagcccaagc agatcgcctg
   219841 cgagcaaaat ttaagctttc gtaaggtagc atttataaat aaaaggaata agttgaacaa
   219901 tcttttagga gaacttgaaa cttattcctt ttttagcgtc aaaatagcta aaattatctt
   219961 tcaaaaatag aaaatgaggt ttttttgatt ttttggaaaa aacaattgac taaacaaacc
   220021 aagagttgta taataaaaca aatatttaaa gcaggaggtt ctggaaatga aaaagtctaa
   220081 gagcaaatat ctaaccttgg caggtcttgt cctgggtaca ggagttttat tgagcgcgtg
   220141 tggaaattct agcactgcat caaaaaccta taactatgtt tattcaagtg atccatctag
   220201 tttgaactat ctagcagaaa accgcgcagc aacatccgat attgttgcaa atttggtaga
   220261 cgggttatta gaaaatgacc aatatgggaa tattattcca tcattagcag aggattggac
   220321 tgtttctcag gacggtttga cctataccta caaacttcgt aaggatgcca agtggtttac
   220381 ttctgaggga gaagaatatg cgcctgtaac tgcccaggat tttgtgacag gtttgcaata
   220441 tgcagctgat aaaaaatcag aagctttgta tctagtgcag gactctgttg ctggtttgga
   220501 tgactatatc actggtaaaa caagcgactt ttcaactgtc ggtgtcaagg cacttgatga
   220561 ccaaacggtt caatatactt tggttaaacc agaactttac tggaattcaa aaacacttgc
   220621 aacgatactt tttcctgtta atgcagattt cctgaaatca aaaggggatg attttgggaa
   220681 ggcggatcca tctagtattt tgtacaatgg acctttcttg atgaaagcac ttgtctcaaa
   220741 atctgctatt gaatataaga aaaaccctaa ttactgggat gctaagaatg tctttgtaga
   220801 cgatgtgaaa ttgacctact atgatggtag cgaccaagaa tcactggaac gtaattttac
   220861 agctggtgct tatactacgg ctcgtctttt tcctaacagc tccagctatg aagggattaa
   220921 agaaaaatac aaaaacaata tcatctatag tatgcaaaat tcaacttcat atttctttaa
   220981 ttttaaccta gataggaagt cttacaatta tacttctaaa acaagtgaca ttgaaaagaa
   221041 atcgactcag gaagcagttc tcaataaaaa cttccgtcag gctatcaatt ttgcttttga
   221101 cagaacatct tatggggctc agtccgaagg gaaagaaggt gcaacaaaga ttttgcgtaa
   221161 cctagtggtt cctccaaact ttgtcagtat caagggaaaa gactttggtg aagttgtagc
   221221 ctctaagatg gtcaactatg gtaaggaatg gcaaggtatc aactttgcgg atggtcaaga
   221281 cccttactac aatcctgaga aagccaaggc taagtttgcg gaagctaaga aagaactcga
   221341 agcaaagggt gttcaattcc caatccactt ggataagact gtggaagtaa cagataaagt
   221401 aggcatacaa ggagttagtt ctatcaaaca atcaattgaa tctgttttag gttctgataa
   221461 tgtagtgatt gacattcagc aattaacatc agatgagttt gacagttcag gctactttgc
   221521 tcaaacagct gctcagaaag actatgattt atatcatggc ggttggggac ctgattatca
   221581 agacccgtca acctatcttg atatctttag tgtcaagaat ggtggggttc tacaaaatct
   221641 tggactcgac cctggtgaag ccaatgacaa ggctaaggca gttggacttg acacttatac
   221701 tcaaatgttg gaagaggcta ataaggagca agacccagcc aaacgttatg agaaatatgc
   221761 tgatattcaa gcttggttga ttgatagttc tttagttctt ccaagtgttt cgcgtggggg
   221821 aacaccatca ttgagaagaa ccgtaccatt tgctgctgcc tatggtttaa ccggtacaaa
   221881 aggggttgaa tcatataaat acctcaaagt acaagataag attgtcacaa cagacgaata
   221941 tgcaaaagcc agagaaaaat ggttgaaaga aaaagaagaa tccaataaaa aagcccaaga
   222001 agaattggca aaacatgtca aataaaatct aattgtagat aagtttgtgt aagaagtctt
   222061 tgtgcttaaa aacgcataat atcaggtata taaaatccta gatgttatgc gttttgttat
   222121 aggaagattt attagatttt atcctcaaat tgagttattc ccgactttat ccgttgaaat
   222181 attataagga gtatttatga aattaaaatt attaagagta gatactaagg tgattatggg
   222241 gagtttctta cttgttctgt ctagtctact tgctttgttg cttcccctta tcttaaaggg
   222301 tttaatagat gggagttcta ttgaaaatat aggttccaaa gtatttcaat cgtttttgat
   222361 ttttattggt caagccttgt tttcttctat tggttactat ctgtttagtc aatcgggtga
   222421 aaaaaagata gcaaaaatca ggaaaaaagt gatagagggg ttgatttatg cagagaaatc
   222481 cttctttgat aagagccaaa gtggggagtt gacttctgcc attgtcaatg acacgagtgt
   222541 cattcgtgag tttttaatta cgactttccc aaatattatt ctgagtttag ttatggtact
   222601 tggttccatt gtagtcttat ttagtcttga ttggaatctt tctctacttt tattcatcac
   222661 tcttccttgt atgatgttta ttatcttgcc cctttccaat atcagtgaaa agtatagtcg
   222721 tcgtttacag gaggaaatcg gatttttaac agggcaattg actgaaaaga ttcaagaaca
   222781 tgaattaatt aagactaacc aagcagagaa aagtgtacag gatgttttgg ataattgtat
   222841 tgaaagggta caaaacaatt cactgaaatc agatagggtt acttcttttg agaccccgtt
   222901 tgctctctta tttatctttg cgactatagc tgtgatgcta acctatgggg gttatcgggt
   222961 cagcgcagga tatatatctg tgggaacctt ggtttcgttt ttgatttacc tctttcaatt
   223021 acttaatcct attagtaata tagctaattt tgtaactgtt tattctagga gcaagggatc
   223081 ttcagttgca ctggagaact tgcttgcagt tcctaaagaa aaatttgagt gaggaaaatc
   223141 ggtatcagga caagggttga attttaacca tgtctatttt ggttatgatg aaaatcgacc
   223201 tgtcttaaag gatattactt gttcaatttt caaggggcaa aaaattgctt ttgttggacc
   223261 atctggatca ggaaaatcaa cgattgtgcg tttgttagag cagttttata aaccgctttc
   223321 aggagatatt ctaatggagc aatcaagtat atatgatttt aacttaaaag aatggagaag
   223381 taaaatcgct tgggtttcac aaaataatgc agtcttatct ggcagtattc gtgacaatct
   223441 ttgtctcggt ttgaatcgct tagtaactga tgatgaattg atgaaagtgc tagacttagt
   223501 atcactaggt gatgagattc gctccatgaa agagggacta gatactgaag ttggtgaacg
   223561 cggacgattc ttgtcagggg ggcaaagcca aagacttcaa atagctagaa cctacttaaa
   223621 agatgctgaa attcttatat ttgatgaagc tactgctaat cttgatgcgg attctgagta
   223681 tgcgattatc agtagcctct attctgtatt aaaggagaag acggttgtga ttatagcgca
   223741 tagtttgtca acggtaaaag atgtggattg tattttcttc ttagaggagg ggaaaatcac
   223801 tggctcagga actcataagg aactactgga aaatcatgag cgttatgctc gttttgtgca
   223861 ggagcaaatg atagagtgaa gtgtcttttg agattcacca ttttatagtc tattaaaggg
   223921 agcaggaaaa actccctttt tatatagttt gaaactataa ctagctcttg aaaagaagaa
   223981 aatgagttga tgaaaataag tggtacaata gttactatag atttggaggt attgtatgag
   224041 caaggaatta cacattaaca caattttggc ccaggcgggt attaagtcag atgaagcgac
   224101 aggtgcattg gtgacaccgc ttcatttttc aacgacctat cagcatccag agtttggtcg
   224161 atctactggg tttgactata cgcgcactaa aaatccaact cgtagtaagg ctgaggaagt
   224221 cttggcgact attgagtcag cagactatgc cttagcgact agctcaggga tgtcagctat
   224281 tgtactggcc tttagcggct ttccagtagg aagtaaggtc ttggcagtgc gtgatcttta
   224341 cggcggttct tttcgctggt ttaaccaagt ggagcaggaa ggtcgtttcc attttaccta
   224401 tgccaataca gaagaagagt tgattgccga gttagaaaag gatgtggatg ttctctatat
   224461 cgaaacccca accaatccct tgatgttgga atttgatatc gaaaaactag caaaattggc
   224521 tcatgctaag ggtgccaaag tggtggtgga caataccttc tatagcccta tctaccaacg
   224581 tccgattgaa gatggagcag atatcgttct ccattcagca accaagtatc tagcaggcca
   224641 caatgatgtc ttggctggag tggttgtgac caatagttta gaactatacg agaagctttt
   224701 ttacaatctc aatacaacag gggcagtctt gtctccattt gacagctacc agttgcttcg
   224761 tggtctcaag accttgtctc ttcgtatgga gcgctcaaca gctaacgccc aagaagtggt
   224821 tgcctttttg aaggattctc cagcagttaa ggaagttctc tacactggtc gtggaggcat
   224881 gatttccttt aaagtagccg atgaaacacg cattcctcat attttgaaca gtctcaaggt
   224941 cttctctttt gcggaaagtt tgggcggagt ggaaagtctt attacttatc caacgactca
   225001 aactcatgct gatattccag cagaagtacg ccattcttat ggtttgacag atgacctctt
   225061 gcgtttgtct attgggattg aggatgctag agatttgatt gcagatttgc gccaagcctt
   225121 agaaggataa gacaaagatg ggaaaatatg attttacaag cctgcccaac cgtttagggc
   225181 accataccta taaatggaaa gaaacagaaa cggatagtga agttctacca gcttggatag
   225241 cggatatgga ctttgtggtc ttgcctgaaa tccgccaagt cgtgcaaact tacgcagacc
   225301 aactggttta tggttatacc tatgccagtg aagacttaat taaggaagtt caaaagtggg
   225361 aagctacaca atacggttac aactttgaca aagaggctct tgtctttatc gagggtgtgg
   225421 taccagccat ctcaacagct attcaaacct ttacaaaaga aggcgatgcg gttttaatta
   225481 acacgcctgt ctacccaccc tttgctcgca gtgtcaagtt gaataatcgt agattgatta
   225541 ctaattcctt agtggaaaag gatggtctgt ttgagattga ctttgaccaa cttgaaaagg
   225601 atttggtgga agaggaggtt aaactctata ttctttgcaa ccctcacaat cctggtggac
   225661 gtgtttggga aaaagaagtg ttggagaaga ttggccaact ctgccaaaaa cacggtgttt
   225721 tgttagtttc ggatgagatt caccaagatt tgaccctctt tggtcacaaa caccagtctt
   225781 tcaataccat caatcctgcc ttcaaaaatt ttgctatcgt cttgagcagt gccactaaaa
   225841 catttaatat tgctggaaca aaaaattcct atgcagtcat tgaaaatcct aagttgagac
   225901 tagctttcca gaaacgcctg ttggccaata atcagcatga aatttcaggc ttgggttatt
   225961 tggcgacaga agctgcctat cgatacggta aagattggct agaggaactc aagcaagtct
   226021 ttgaagacca catcaattat gtggtggatc tatttggaaa agagactaaa atcaaggtca
   226081 tgaaaccgca aggtacctac ttgatttggc ttgacttttc agcctatgac ctgactgatg
   226141 aaacattgca agagttgttg agaaatgaag ccaaggttat cctcaaccgt ggtttggatt
   226201 ttggagagga aggaagtctc catgcccgca tcaatatagc tatgcccaaa tctctgttgc
   226261 aagaagtctg tcagcggatt gtggctactt ttgccaaacg ttaaaaatcc agccttctag
   226321 gagaaaagtc ttcctagaag gctattttca taggcgaaaa tatggtataa taaaaagata
   226381 aggtaaaggt gaaaatatgg ctaaattgat tccggggaaa attcgtatcg aaggtgttgc
   226441 cctttatgaa actggtaagg ttgatatcat caaggaaaag aacaatcggc tctacgctcg
   226501 cgttgcagaa gaagaactgc gctatagttt agaggatgat ttggtttttt gtgcctgtga
   226561 tttttttcaa aagaggggtt actgtgtgca tttggcagcg ctagagcatt ttctgaaaaa
   226621 tgatgagcgt ggtcaggaaa tcttgtggag tctggaagaa ggtcatgaag aaaaagaggc
   226681 tgttgaaacc aaggtgacct tgggtggcaa gtttttggat cgaattttat ctccaaaatc
   226741 agaatgcgcc tatgagttat cagctgtggg tcaggtggaa gcaggaacca atcatatctt
   226801 gtggactctg agaatcggcc aaatcaatag ccaaaaatac tatgtcattc gggatattcc
   226861 acttttttta aggattgtcg agcagagaaa gtcgtatatg attggcaaga tttatgagga
   226921 gtctctttct tgggaagcct ttgatgatgc cagccaagaa cttttgactt tcttgcacgg
   226981 actaacggag gaagggctgg tttcagacct ctttttccaa aaccaaggtc ggcacctctt
   227041 tttccctctg accttttttg agcagggtgt gaatttactg atggccttgc cccattttca
   227101 atttgaccat caagtggata gctaccaaac cctgcttttt caggatatgc atgctgatgc
   227161 caatctattt gcctttacag taacagaata ctcggactat tttgaaatgg aaatcagtga
   227221 gagtcctagg gtcaatgtct tttatcaggg agcagtactt ttccataaag gtcaggttta
   227281 ttttttaaca gaccagcaga tgcgtcttct caaggaaatt aaagcgttac ctgtgggtca
   227341 acaaggaaag aaatacctgc aatttgatag cagtgatcga gacaaattgg cctcctgtct
   227401 gactcttttt atccagatgg gcaccgtttc agctccagaa cgtctacaaa tcaaaacttt
   227461 tgcgccctct ttttactttg acagggaaga agataatcgg attcgtttag aaattcagtt
   227521 tgattatgga aatagacagg tatctagccg acaagagcta gaagaattac cattttcaag
   227581 tgacgcggac ttagaagaaa gaattttcca agtctgtttg gctgcgggct ttgaggccga
   227641 ttttcaatct tggcgtcagg ccttaaaagc ggagtctgtc tatcattttt ttcatgatat
   227701 cattccagtc tttgaaaaac tcgggcatgt tgacctatca gataaactag aagagcttta
   227761 tagcctagcg agtcctcagg tgcagattgc ctccaaggga ggtctcttgg aaatccagtt
   227821 tgattttcaa aatattgtcc aggaggaaat cgaccaagcc atgcaggcct tggttgccaa
   227881 tcaggatttt tatattgatt cgtctaatca agtttacttt ttcgatgaag aaaccaagaa
   227941 aattcgccaa aatttacagg aactggggca atttgaatta aaagatggga ccttgcaggc
   228001 tcggaaatcc ttgacctaca gtttagctca tctctttgaa gggcgagacc gtgtttcttt
   228061 ttcacaagaa ttccagaatc tggcccagga tttgacgcat ccagaggact ttcctttgca
   228121 agcaactcag gtcaaggctg acttgcgaga ttatcaggaa aagggaattg gctggttgca
   228181 gatgctccat cattatggtt ttggtgggat tttggctgat gatatgggac ttgggaaaac
   228241 ccttcagacc attgcttttt tgactagtca agtgacaaaa gaaagtcggg ttttgattct
   228301 cgctccgtcg ggtttgattt acaactgggc agatgagttt cagaaatttg ctccacagtt
   228361 ggatgtgact gttgttcatg gtttgaaagc aagtcgtgag gagattcttg ccgagagcca
   228421 tcaaatctat gtgactagct atgccacctt ccgtcaggac agtgagcttt atcaggggat
   228481 ggcctttgac ttccttttct tagatgaagc tcaggtcatg aaaaatgccc agaccaagat
   228541 tgcccagacc ttgagacaat ttgtggtgcc gtcggtcttt gccttgtcag gaactccgat
   228601 tgaaaaccat ctgggtgagt tgtggtctat tttccaaatc gtcatgcccg gacttttgcc
   228661 aagcaagaaa gaatttatga aattgccagc agagcgagtg gctcagttta tcaagccttt
   228721 cgtgatgcga cgcaagaaag aagaagttct gactgaattg ccagacttga ttgaggtggt
   228781 ttataaaaat gaactggaag accagcaaaa ggctatttac cttgcccagt tacaacagat
   228841 gcgagaccat ctggctcaag tgtcagaaca ggaatttcag cgaagtcgtg tggaaatttt
   228901 atctggtttg atgcgcttgc gtcaaatatg tgacactcct gccctgttta tggaagatta
   228961 tcagggagcc agcggcaaac tagatagtct ccgagaccta ctggtacagg tggcagacgg
   229021 cggacaccgt gtcttgattt tctctcagtt caagggaatg ttggaaaaaa ttgaacaaga
   229081 actgccagac ttgggcctga cttcctttaa aattacgggt tcaaccccag ccaaggaaag
   229141 acaagacatg accaaggcct ttaaccaagg agaaagagat gcctttctga tttccctcaa
   229201 ggctggtggg gtcggtctga acctgacagg tgcagataca gtgatcttgg ttgacctttg
   229261 gtggaatcct gcggtggaag cgcaagccat tggccgtgcc catcggatgg gtcaggaaga
   229321 aacggttgag gtctatcgct tggtgaccaa gggaaccatt gaagaaaaaa ttcaggaact
   229381 ccaagaacaa aagaaacatc tggtgtcaca agtattggac ggcacagagt cacgtggtag
   229441 tctgacccta gcagaaatta gagaaatttt gggaatttct gaagccagca cttgaaaaat
   229501 caagacaata cgctataatg aagtgttgaa aggaaataga aaatgaaaca agaacgattt
   229561 ccattggtgt cagatgacga ggtcatgttg actgaaatgc cagtcatgaa tctctatgat
   229621 gagtctgatc tgatcagtaa tatcaagggt gagtatcgag ataaaaatta tttagaatgg
   229681 gctcctattg ctgaagaaaa accagtaaaa ccgattgaaa agcaagtcga aaaacctaaa
   229741 aaggctcctt taggggttaa aaaagaagga aagagctatg cggaggtggc gcgtgaagaa
   229801 gcgcgtgcgg acttgaaaaa gaaacgctct gctaactacc taactcagga tttcagcctt
   229861 gcgagacgtc attctcagcc cagtctagtt agacagggca atcaaccgac aactcctttc
   229921 caaaaggaaa atcctggtga atttgtcaaa tatagccaaa aattgaccca gtctcattat
   229981 atcttggcgg aagaagttca ttctatccct accaagaatg aagaagtgtc agcacctgct
   230041 ccaaagaaaa acaattatga ttttctaaag aagagccaaa tctacaataa aaaaagtaaa
   230101 caaacagaac aagaacgtcg ggttgcccaa gagttgaatc tgaccagaat gacagaatag
   230161 gggagaaaac atgtcaaaga catatcattt tatcggaatt aagggatcag ggatgagtgc
   230221 cttggccttg atgttgcacc agatggggca caaggttcag ggatcagatg ttgaaaagta
   230281 ctactttacc caacgcggtc ttgagcaggc aggaattacc attcttcctt ttgatgaaaa
   230341 gaatctagac ggtgatatgg aaattatcgc tggaaatgcc tttcgtccag ataacaacgt
   230401 cgaaattgcc tatgcggacc aaaatggtat cagctacaaa cgttaccatg agtttctagg
   230461 tagctttatg cgtgactttg ttagcatggg agtagcagga gcacatggaa aaacttcaac
   230521 gacaggtatg ttgtctcatg tcttgtctca cattacagat accagcttct tgattggaga
   230581 tgggacaggt cgtggttcgg ctaatgccaa atattttgtc tttgaatctg acgaatatga
   230641 gcgtcacttc atgccttacc acccagaata ctctattatc accaacattg actttgacca
   230701 tccagattat ttcacaagtc tcgaggatgt tttcaatgcc tttaacgact atgccaaaca
   230761 aattaccaag ggtctttttg tctatggtga agatgctgaa ttgcgtaaga ttacgtctga
   230821 tgcaccaatt tattattatg gttttgaagc tgaaggcaat gactttgtag ctagtgatct
   230881 tcttcgttca acaactggtt caaccttcac cgttcatttc cgtggacaaa acttggggca
   230941 attccacatt ccaacctttg gtcgtcacaa tatcatgaat gcgacagccg ttattggtct
   231001 tctttacaca gcaggatttg atttgaactt ggtgcgtgag cacttgaaaa catttgccgg
   231061 tgttaaacgt cgtttcactg agaaaattgt caatgataca gtgattattg atgactttgc
   231121 ccatcatcca acagaaatta ttgcgacctt ggatgcggct cgtcagaaat acccaagcaa
   231181 ggaaattgta gcagtctttc aaccgcatac ctttacaaga accattgccc tgttggacga
   231241 ctttgcccat gctttaaacc aagcagatgc tgtttatcta gcgcaaattt atggctcggc
   231301 tcgtgaagta gatcatggtg acgttaaggt agaagaccta gccaataaaa tcaacaaaaa
   231361 acaccaagtg attactgttg aaaatgtttc tccactccta gaccatgaca atgctgttta
   231421 cgtctttatg ggagcaggag acatccaaac ctatgaatac tcatttgagc gtctcttgtc
   231481 taacttgaca agcaatgttc aataggatgt tcccatggaa attccaatta agatcattca
   231541 ggcaagcaag tttgatttgc ctgagatagg ggcacttcag acctcgtctt ttccagctga
   231601 aaagcagcaa ctttcccata ttttagaaga aagtatccgt aagtgtgcgg atacctttct
   231661 tctagctagg gatgaaaatc aacttttagg ctatatttta tcaagtcccc agtcagacaa
   231721 tccgcaatgt ctaaaagtac attctttagt catcgagtct gaccatcaga gacagggcct
   231781 gggaacactt cttcttgcag ccttgaaaga ggtggcagtt gagctggatt acaaagggat
   231841 tcgtttggag agtcctgatg agctgctttc ctattttgaa atgaacggtt ttgttgatga
   231901 agaagaaatt ttgctctatg caactagcca gggctatagt atgatttggt ttaatccctt
   231961 ttatctggag gaacaatgaa aatcagacaa gcaagattag aagatttgga tcggattgtt
   232021 gaacttgaat ttgaaaattt ttcggtcgaa gaagccattc ctccttctgt ctttgaagca
   232081 catttgagag aaattcagac ctcttttctg gttgctgaaa aagaaggaag aatcatgggt
   232141 tatatcgaag gaccagttgg cctgcaccgc catctgcaag accagtcttt tacagaagaa
   232201 ataaaagact atagtcatga gcctggtggt tatatctctg tgacctgtct gtctattgcc
   232261 aaggaggcac agggactcgg actgggtcag aaattgctga cagccttgaa agaagttgct
   232321 cttgaagatg agagagatgg cattaatcta acctgtcatg actatctcat cgcctattat
   232381 gaaaaacatg gatttgtcaa cgaaggccag tcccagtcaa cctttgcagg ggaaacatgg
   232441 tatgatatgg tctgggaaat gaaaaaataa gttaggaaaa gtatcataga ttgctttttt
   232501 tggactttta agatataata ttatggatta tcaacaagga ggaaaaactt ttgagtgaaa
   232561 agtcaagaga agaagagaaa ttaagcttta aagagcagat tctgagagat ttagaaaaag
   232621 taaaaggcta tgatgaagtt ctgaaagaag atgaggcagt agttcgcact cctgcaaatg
   232681 aaccttcagc tgaagaactc atggctgatt ccttgtcaac ggtagaggag attatgagaa
   232741 aagctcctac cgtgcctact cacccaagtc aaggtgtacc agcttctcca gcagatgaga
   232801 ttcaaagaga aactcctggt gttccaagtc atccaagtca agatgtacct tcttctccag
   232861 cggaagaaag tggatcaaga ccaggtccag gtcctgttag acctaagaaa cttgaaagag
   232921 aatacaatga aaccccaaca agggtagctg tttcctatac gacggcagag aaaaaagcag
   232981 aacaagcagg tccagaaaca cctacgcctg ctacagaaac agtggatatc atcagagata
   233041 catcacgtcg tagccgtaga gaaggagcaa aacccgttaa gcctaagaaa gagaagaagt
   233101 cacatgtgaa agcttttgtg atttcattcc ttgtattcct tgccttgctc tcagcaggtg
   233161 gttactttgg ttaccagtac gtgctagatt ccttattacc tatcgatgct aattctaaga
   233221 aatatgtgac ggttggaatt ccagaaggtt caaacgttca agaaatcggt acgacgcttg
   233281 aaaaagctgg tttggtaaag catggtctga tttttagttt ttatgccaag tataaaaatt
   233341 ataccgactt gaaagcaggt tactacaatt tgcaaaagag tatgagtaca gaagacttac
   233401 tcaaagagtt gcaaaaaggt ggaacagatg aaccgcaaga acctgtactt gcgactttga
   233461 caattccaga aggttatacc ttggatcaga ttgctcaaac tgtgggtcaa ttgcaaggtg
   233521 acttcaaaga gtctttgaca gcggaggctt tcttggctaa agttcaagat gagacgttta
   233581 tcagtcaagc agtagcgaaa tatcctactt tactggaaag tttgcctgta aaagacagcg
   233641 gtgcgcgtta tcgtttggaa ggataccttt tcccagctac atactctatc aaggaaagca
   233701 caactattga gagcttgatt gatgagatgt tagctgctat ggataagaac ctatctcctt
   233761 actatagtac tatcaaatct aaaaacttga ctgtcaatga gttgttgacc attgcttcct
   233821 tggtcgaaaa agaaggtgcc aagacagaag atcgtaagct cattgcaggt gtattctaca
   233881 atcgtttgaa tcgtgatatg ccacttcaaa gtaatattgc aatcttgtat gcccaaggaa
   233941 aactggggca aaatatcagt ctagctgagg atgttgcgat tgataccaac attgattcac
   234001 cttataatgt ttataaaaat gtaggtctca tgcctggtcc agtcgatagt ccaagtctgg
   234061 atgcgattga gtcaagcatc aatcaaacta agagcgataa cctctacttt gtagcagatg
   234121 tcacagaagg caaggtctac tatgctaaca atcaagaaga ccacgaccgc aatgtcgctg
   234181 aacatgtcaa cagcaaatta aactaaacaa actaaaatta tgtgatactt cacataattt
   234241 tctttagaaa atattatcag aagaaagttg agaaaaatgg cagaaaaaac atatcctatg
   234301 acccttgagg aaaaggagaa acttgaaaaa gaattagaag aattgaaatt ggttcgtcga
   234361 ccagaagtgg tagaacgcat taagattgcc cgttcatacg gtgatctttc agaaaacagt
   234421 gagtacgaag cagctaagga tgaacaagcc tttgtcgaag gacaaatctc tagcttagaa
   234481 acaaaaatcc gctatgctga aatcgtcaat agcgacgcag ttgcccagga cgaagtagcg
   234541 attggtaaaa cagtcaccat ccaagaaatt ggtgaggacg aagaagaagt ttatattatc
   234601 gtaggttcag ctggtgcgga tgcctttgca ggtaaggttt caaatgaaag cccaattggg
   234661 caggccttga ttggcaagaa aacaggtgac acagcaacca ttgaaacgcc tgttggtagc
   234721 tatgatgtaa aaatcttgaa ggttgaaaaa acagcctaaa aacagaaaaa ggagtgggga
   234781 ggcgatgtgc ttcactcact cctttttcca ttttgctatt cttcgaaaat ctcttcaaac
   234841 cacgtcagcg tcgccttgcc gtatgtatgg ttactgactt tgtcagtttc atttacaacc
   234901 tcaaaaca
//
LOCUS       DAVHKZ010000002        77038 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000002 DAVHKZ010000000
VERSION     DAVHKZ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 77038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77038
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.002"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(44..754)
                     /locus_tag="VVO74_000239"
     CDS             complement(44..754)
                     /locus_tag="VVO74_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU5694339.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(757..2448)
                     /locus_tag="VVO74_000240"
     CDS             complement(757..2448)
                     /locus_tag="VVO74_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU5694340.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(2460..3470)
                     /locus_tag="VVO74_000241"
     CDS             complement(2460..3470)
                     /locus_tag="VVO74_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694341.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(3573..4640)
                     /locus_tag="VVO74_000242"
     CDS             complement(3573..4640)
                     /locus_tag="VVO74_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU5694342.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELASKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALVGQKEQNVVFKVMSPEIGVPFVTEQTMILS
                     TSKKQALAKEFIDWFGQSEIQVEYSKNFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            complement(4665..5324)
                     /locus_tag="VVO74_000243"
     CDS             complement(4665..5324)
                     /locus_tag="VVO74_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU5694343.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            complement(5504..6514)
                     /gene="galE"
                     /locus_tag="VVO74_000244"
     CDS             complement(5504..6514)
                     /gene="galE"
                     /locus_tag="VVO74_000244"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU5694344.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKPALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            complement(6527..8002)
                     /gene="galT"
                     /locus_tag="VVO74_000245"
     CDS             complement(6527..8002)
                     /gene="galT"
                     /locus_tag="VVO74_000245"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU5694345.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            complement(8015..8656)
                     /locus_tag="VVO74_000246"
     CDS             complement(8015..8656)
                     /locus_tag="VVO74_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEU5694346.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERIELI
                     KEDLIINESVLNVDKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIVEILKNL
                     QIIQNNEILKKIISEIKILHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELST
                     NIEKKIMNYIFEDDGNVSEVIGALDIIHHLDKIAHTTQSIYKWIMYRKYGNIN"
     gene            complement(8714..8926)
                     /locus_tag="VVO74_000247"
     CDS             complement(8714..8926)
                     /locus_tag="VVO74_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694347.1"
                     /translation="MDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELI
                     KMRFNSSAIDPIYGKKDDASIVVIDV"
     gene            complement(9269..9565)
                     /locus_tag="VVO74_000248"
     CDS             complement(9269..9565)
                     /locus_tag="VVO74_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694348.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            complement(9549..11708)
                     /gene="pfbA"
                     /locus_tag="VVO74_000249"
     CDS             complement(9549..11708)
                     /gene="pfbA"
                     /locus_tag="VVO74_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEU5694349.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(12839..14065)
                     /locus_tag="VVO74_000250"
     CDS             complement(12839..14065)
                     /locus_tag="VVO74_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU5694350.1"
                     /translation="MPNYNIPFSPPDITEAEITEVVDTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSIYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAASRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(14108..14800)
                     /locus_tag="VVO74_000251"
     CDS             complement(14108..14800)
                     /locus_tag="VVO74_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU5694351.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(14973..16724)
                     /locus_tag="VVO74_000252"
     CDS             complement(14973..16724)
                     /locus_tag="VVO74_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694352.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATMVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQETSDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGV
                     TYHKMYSLQAGAMADTL"
     gene            complement(16714..18459)
                     /locus_tag="VVO74_000253"
     CDS             complement(16714..18459)
                     /locus_tag="VVO74_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694353.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     PLVAILPLPFMAYTTSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLLAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGTI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGTHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(18665..18961)
                     /locus_tag="VVO74_000254"
     CDS             complement(18665..18961)
                     /locus_tag="VVO74_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU5694354.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(19114..19571)
                     /locus_tag="VVO74_000255"
                     /pseudo
     CDS             complement(19114..19571)
                     /locus_tag="VVO74_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            19705..20532
                     /gene="xth"
                     /locus_tag="VVO74_000256"
     CDS             19705..20532
                     /gene="xth"
                     /locus_tag="VVO74_000256"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU5694355.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            20544..20681
                     /locus_tag="VVO74_000257"
     CDS             20544..20681
                     /locus_tag="VVO74_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU5694356.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLLKSV
                     N"
     gene            20792..20920
                     /locus_tag="VVO74_000258"
     CDS             20792..20920
                     /locus_tag="VVO74_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HEU5694357.1"
                     /translation="MKANYPIYRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      21303..21398
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            21798..22379
                     /locus_tag="VVO74_000259"
     CDS             21798..22379
                     /locus_tag="VVO74_000259"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU5694358.1"
                     /translation="MKLLEDRILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            22379..23641
                     /locus_tag="VVO74_000260"
     CDS             22379..23641
                     /locus_tag="VVO74_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU5694359.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPLDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(23692..24153)
                     /locus_tag="VVO74_000261"
     CDS             complement(23692..24153)
                     /locus_tag="VVO74_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEU5694360.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(24150..24914)
                     /locus_tag="VVO74_000262"
     CDS             complement(24150..24914)
                     /locus_tag="VVO74_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HEU5694361.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(25095..25499)
                     /locus_tag="VVO74_000263"
     CDS             complement(25095..25499)
                     /locus_tag="VVO74_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU5694362.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            complement(25569..27050)
                     /locus_tag="VVO74_000264"
     CDS             complement(25569..27050)
                     /locus_tag="VVO74_000264"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU5694363.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLEMIEDSQTAREILGTELMDLVTPYPSQVNRDFWEAYVHSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(27069..28247)
                     /locus_tag="VVO74_000265"
     CDS             complement(27069..28247)
                     /locus_tag="VVO74_000265"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU5694364.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            28412..29419
                     /gene="galR"
                     /locus_tag="VVO74_000266"
     CDS             28412..29419
                     /gene="galR"
                     /locus_tag="VVO74_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU5694365.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(29465..30502)
                     /locus_tag="VVO74_000267"
     CDS             complement(29465..30502)
                     /locus_tag="VVO74_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU5694366.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(30503..30856)
                     /locus_tag="VVO74_000268"
     CDS             complement(30503..30856)
                     /locus_tag="VVO74_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU5694367.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(31100..31990)
                     /locus_tag="VVO74_000269"
     CDS             complement(31100..31990)
                     /locus_tag="VVO74_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEU5694368.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            32123..32659
                     /locus_tag="VVO74_000270"
     CDS             32123..32659
                     /locus_tag="VVO74_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU5694369.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(32825..33631)
                     /locus_tag="VVO74_000271"
     CDS             complement(32825..33631)
                     /locus_tag="VVO74_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEU5694370.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(33976..35496)
                     /locus_tag="VVO74_000272"
     CDS             complement(33976..35496)
                     /locus_tag="VVO74_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU5694371.1"
                     /translation="MTNLIATFQDRFGDWLTALSQHLQLSLLTLLLAILLAIPLAVYL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLNGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITENQMSQLNYQVGVEGKSAEQVAKEFLQEQGLLKK"
     gene            complement(35489..36217)
                     /locus_tag="VVO74_000273"
     CDS             complement(35489..36217)
                     /locus_tag="VVO74_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694372.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVEENIALIPEM
                     KGWTKEEIAQKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKILLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVS
                     NPETILKAPATDFVADLFGGSIHD"
     gene            complement(36232..36996)
                     /locus_tag="VVO74_000274"
     CDS             complement(36232..36996)
                     /locus_tag="VVO74_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU5694373.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(37000..37443)
                     /locus_tag="VVO74_000275"
     CDS             complement(37000..37443)
                     /locus_tag="VVO74_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU5694374.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(38125..38421)
                     /locus_tag="VVO74_000276"
     CDS             complement(38125..38421)
                     /locus_tag="VVO74_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU5694375.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(38443..39507)
                     /gene="pepA"
                     /locus_tag="VVO74_000277"
     CDS             complement(38443..39507)
                     /gene="pepA"
                     /locus_tag="VVO74_000277"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU5694376.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPYVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            39908..40609
                     /locus_tag="VVO74_000278"
     CDS             39908..40609
                     /locus_tag="VVO74_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEU5694377.1"
                     /translation="MTKTILVTGGTSYISSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNAAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            41032..41991
                     /locus_tag="VVO74_000279"
     CDS             41032..41991
                     /locus_tag="VVO74_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5694378.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            41981..42937
                     /locus_tag="VVO74_000280"
     CDS             41981..42937
                     /locus_tag="VVO74_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU5694379.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSFFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            42934..43686
                     /locus_tag="VVO74_000281"
     CDS             42934..43686
                     /locus_tag="VVO74_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU5694380.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            43782..44747
                     /locus_tag="VVO74_000282"
     CDS             43782..44747
                     /locus_tag="VVO74_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5694381.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(44972..45214)
                     /gene="yidD"
                     /locus_tag="VVO74_000283"
     CDS             complement(44972..45214)
                     /gene="yidD"
                     /locus_tag="VVO74_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU5694382.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDRFSLKRNQEGE"
     gene            complement(45214..45936)
                     /locus_tag="VVO74_000284"
     CDS             complement(45214..45936)
                     /locus_tag="VVO74_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU5694383.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVVNKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(45923..46492)
                     /locus_tag="VVO74_000285"
     CDS             complement(45923..46492)
                     /locus_tag="VVO74_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU5694384.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(46511..47239)
                     /locus_tag="VVO74_000286"
     CDS             complement(46511..47239)
                     /locus_tag="VVO74_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU5694385.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(47239..47979)
                     /gene="xerD"
                     /locus_tag="VVO74_000287"
     CDS             complement(47239..47979)
                     /gene="xerD"
                     /locus_tag="VVO74_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU5694386.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(47970..48431)
                     /locus_tag="VVO74_000288"
     CDS             complement(47970..48431)
                     /locus_tag="VVO74_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU5694387.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(48428..48949)
                     /locus_tag="VVO74_000289"
     CDS             complement(48428..48949)
                     /locus_tag="VVO74_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU5694388.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(48925..49896)
                     /locus_tag="VVO74_000290"
     CDS             complement(48925..49896)
                     /locus_tag="VVO74_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU5694389.1"
                     /translation="MTNKIYEYKDDRDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(49893..50687)
                     /gene="racE"
                     /locus_tag="VVO74_000291"
     CDS             complement(49893..50687)
                     /gene="racE"
                     /locus_tag="VVO74_000291"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU5694390.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(50894..51142)
                     /locus_tag="VVO74_000292"
     CDS             complement(50894..51142)
                     /locus_tag="VVO74_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU5694391.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(51398..53023)
                     /gene="treC"
                     /locus_tag="VVO74_000293"
     CDS             complement(51398..53023)
                     /gene="treC"
                     /locus_tag="VVO74_000293"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU5694392.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMTDYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(53201..55168)
                     /gene="treP"
                     /locus_tag="VVO74_000294"
     CDS             complement(53201..55168)
                     /gene="treP"
                     /locus_tag="VVO74_000294"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU5694393.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATNPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            55353..56063
                     /gene="treR"
                     /locus_tag="VVO74_000295"
     CDS             55353..56063
                     /gene="treR"
                     /locus_tag="VVO74_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU5694394.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(56096..56899)
                     /locus_tag="VVO74_000296"
     CDS             complement(56096..56899)
                     /locus_tag="VVO74_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU5694395.1"
                     /translation="MTSLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMTDLMKPKLLLLDEHTAALDPKTSQMVMNLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(56912..57805)
                     /locus_tag="VVO74_000297"
     CDS             complement(56912..57805)
                     /locus_tag="VVO74_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5694396.1"
                     /translation="MNFVLSSLSEGLLWSIVAIGVYLTFRILDIADMTAEGAFPLGAA
                     VVVSQIQAGANPWLATLLALLAGMVAGLVSGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGTVFSLSLACFLLVCLVLTLLMKTEIGLVL
                     RSTGDNIPMSEANGVNVDTMKIVGYMISNGLIALCGSLFAQNDGFSDVTSGTGTIVVG
                     LSSVIIAEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYEIPNLDQNLVRLFNAILLAL
                     VLFAPELQKRLKIRGLKLRNE"
     gene            complement(57817..58677)
                     /locus_tag="VVO74_000298"
     CDS             complement(57817..58677)
                     /locus_tag="VVO74_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU5694397.1"
                     /translation="MSQFITHQSLYATREGFVDKLAKQGYVEGENIEIDLQNAQGEQR
                     NLKTISQQLAESSDVVLAIARPSAQSLANTTQTTPVIFSAVTDPVSAKLVESREHPGG
                     NVTGTSDQSSDAISTQINLIKKVLPKAKTIGILYTQSEPNSVVQKDEAKRLLKEKGFT
                     VVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISLTMETVKQVSIKHKVPVFGGSTE
                     MIAVGGLYNYGTNYEELGRQTARMLIRVLKGEKPENIAVELPEKLELHTNQEMADALG
                     IDISKLEGKE"
     gene            complement(59244..60170)
                     /locus_tag="VVO74_000299"
     CDS             complement(59244..60170)
                     /locus_tag="VVO74_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694398.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(60181..61248)
                     /locus_tag="VVO74_000300"
     CDS             complement(60181..61248)
                     /locus_tag="VVO74_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694399.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            complement(61257..62183)
                     /locus_tag="VVO74_000301"
     CDS             complement(61257..62183)
                     /locus_tag="VVO74_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5694400.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            complement(62183..63679)
                     /locus_tag="VVO74_000302"
     CDS             complement(62183..63679)
                     /locus_tag="VVO74_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5694401.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSISLPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            complement(63746..65725)
                     /locus_tag="VVO74_000303"
     CDS             complement(63746..65725)
                     /locus_tag="VVO74_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5694402.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            complement(66411..67604)
                     /locus_tag="VVO74_000304"
     CDS             complement(66411..67604)
                     /locus_tag="VVO74_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU5694403.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            complement(67742..69184)
                     /gene="gtfA"
                     /locus_tag="VVO74_000305"
     CDS             complement(67742..69184)
                     /gene="gtfA"
                     /locus_tag="VVO74_000305"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEU5694404.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTMLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            complement(69484..70317)
                     /locus_tag="VVO74_000306"
     CDS             complement(69484..70317)
                     /locus_tag="VVO74_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU5694405.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            complement(70331..71197)
                     /locus_tag="VVO74_000307"
     CDS             complement(70331..71197)
                     /locus_tag="VVO74_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU5694406.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAAFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            complement(71211..72470)
                     /locus_tag="VVO74_000308"
     CDS             complement(71211..72470)
                     /locus_tag="VVO74_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU5694407.1"
                     /translation="MEWYKKIELLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            complement(72562..74724)
                     /locus_tag="VVO74_000309"
     CDS             complement(72562..74724)
                     /locus_tag="VVO74_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU5694408.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHITLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            74832..75692
                     /locus_tag="VVO74_000310"
     CDS             74832..75692
                     /locus_tag="VVO74_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU5694409.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIS
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQSPSHTRKEYS
                     QYQLVRKATL"
     gene            75689..76624
                     /locus_tag="VVO74_000311"
     CDS             75689..76624
                     /locus_tag="VVO74_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEU5694410.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEINSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(76750..76837)
                     /locus_tag="VVO74_000312"
     tRNA            complement(76750..76837)
                     /locus_tag="VVO74_000312"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(76801..76803),aa:Ser,seq:gct)
     gene            complement(76844..76917)
                     /locus_tag="VVO74_000313"
     tRNA            complement(76844..76917)
                     /locus_tag="VVO74_000313"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(76881..76883),aa:Ile,seq:gat)
     gene            complement(76953..77023)
                     /locus_tag="VVO74_000314"
     tRNA            complement(76953..77023)
                     /locus_tag="VVO74_000314"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(76989..76991),aa:Gly,seq:tcc)
BASE COUNT        23298 a        16978 c        13722 g        23040 t
ORIGIN      
        1 aaaacaaaag gacaaaaaca tctgtccctt tgtttactaa atttcagcta atttcttcga
       61 cataaataac acctacaata ttagcaattt cttccatcag tcgaagatgt tcaaatctac
      121 ctgataattc cagagtaata aatgacgcta tttttttgtc cggaacatca aagtattcaa
      181 ttctgtcaga attaacatct ccaaacgctg ttcttgaatc ggtcattctg ataccatttt
      241 ctgcacaata aaccaataca cgattatagg cttctgtaga tttaactact atatacaatt
      301 caatcatttt agaacgattt tgcagatatt tttttagtgg ttggaacatg gatatcacac
      361 cccaaacaga aatggctact aaaagagctc cctcataaaa acctactcca atagctaatc
      421 caattcctgc cgaagcccaa atgcctgctg cagttgtcaa acctgtaatt ttctttttat
      481 ctgtaataag aatcgttcca gcgcctagaa aacccacacc tgatataact tgagctccta
      541 atcgtgtagg atctcctgtc ccaaatttat aagatacgta ttcattcgtc atcataatca
      601 aacatgcagc tagacaaaca atactataag ttcggatgcc tgcaggctgg gatttgctcc
      661 ctctctctaa accaattata ctaccaatga ctactgataa aacaatcctg acaactattt
      721 caatatttga taacccaaga ctagtggctg tcatgattat ttccttactt tacgccccgg
      781 tctttgtgtg aagtataata ccgttccaga aataatcatc agaacaattg tataaacaaa
      841 taccagagct tgtgcattag atgttgctgt ttcatcacct gcagatcgaa tcgtaatacc
      901 taatggttga gctaggggat ggtaaaggaa tacagataag tcgaagtcag ttaataaaga
      961 gttaaagttt aaagcaataa cagagagaac aaccggtaaa ataaatggaa tgataacctt
     1021 catcatagta taaaaaggtg aagcacccat acttcttgct gcatcttcca tctcatcatc
     1081 aacactaaat aaaatagcac gtaccattct ataagaaaat gggattttta caactatata
     1141 tgcaataagt agaattacca aactacctac caaaatctga ttcaagacaa gaaattgtgg
     1201 ctgattaaaa gtaaataata aacttactgc taaaagtgta cttggtagta accaaggaag
     1261 tagagcacca tattcaaata agaaatcaaa acgagattta tgttttctga caacacgagc
     1321 aaatacaact gcgagaattg ttgctgttgt cgcagcaata atagaataaa taaagctgac
     1381 caagaatgga gagaatgccg cactattact aaagaataag cgataatttt ctaaagtaaa
     1441 gtttgataat gttaagttac ctgtttgaat tgcaactgga tctgtaaatg agtataatac
     1501 tataaaaatt agtggaagca tgaaaactgt gaacaatcca tatgctacaa tgtgagcaat
     1561 gatattccaa ggcttagacg caattttttg ttttttaaga ggcgctttag tcttagagat
     1621 agaaatataa tttccacctt tttctatctt attcatgata gtaagcaaaa ttgtagttgc
     1681 aatacctaaa ataattgcaa gtaaggcagc taaatcacga gaattcccca tccctgcaaa
     1741 tgtaataatc attggattta tagtttgaaa ttctttacca ccaacaatca tgggtgctgc
     1801 tactgcagat aaaccactaa gaaaaaccat aatagtaagt gcaaatagag ttggaattaa
     1861 ggttggtaac actacttttc ggaaaacagt aaatggtttt gctcccatat ttcgagcagc
     1921 ctcaatagtg tgatagtcaa cgcttcgaat tgtatttgtt aaaaacaatg tatgattagc
     1981 agttcctgaa aatgtcataa tgaataagac tgcaccatac ccaataaacc agttagggtc
     2041 taaagaaggg ataacatttt gtaaaaattt tgtaatcaat ccataaggac catagacaaa
     2101 tttatatcca gtcgctaaaa ccactcctcc ataaattaaa gaggtcatat aacctaattt
     2161 taaaatttta gcacctttaa tatcaaagta ctctgtaaat agaacacaaa gaatacctac
     2221 gacattaact gtaataataa gtgaaaatgc taacttaaaa ctgttcataa tactctgaag
     2281 tgccctctga gattttagaa cacgatgtac agcatcaagg gaaaattctc ctccttttac
     2341 aaatacattc actactagat caaagtttgg ataaataata aatgttacta agaaccagat
     2401 taaccctaaa cgaataagcc aatcttttaa atttaattta tgacgcatac tgcacctcct
     2461 taaaattgca gaacgtctga tggtgtgata aataattcca cactttctcc gacagatcta
     2521 atagcagcct gactatcaat acttgttaca ttaagaatct gactttcaga aacttttatt
     2581 gtatagtgaa ttgtaactcc agaaaactca acatcaataa ttgtcccttt tagaataaaa
     2641 tcttgttcag tttcacgatt gaatcgaact ttctctaatc gaatgtatcc ttttttatcc
     2701 tctaagaaaa cgcttgtatt tttcaataat acttcgtgga ctgtttcatc ggtcaaaaca
     2761 ttaatatctc caataaaatc acatacaaat tcagtttgag aattatgata aatctctact
     2821 ggtgtaccga cctgttcgat gtatccattg ttaaagactg caattctatc agataaagtc
     2881 aaggcttcct cttgatcatg agtaacatat aaagtagtaa tacctaactc tttttgaagt
     2941 cttttcaact cttttctcaa atctacacgt aattttgcgt caaggtttga caatggttca
     3001 tctagacaaa gaattttagg ttcaagaacc agagcacgag ccaatgctac cctttgttgt
     3061 tgacccccag ataattctga tacattacgc tgtaactgtt gatcagagat cttaattttt
     3121 gctgccactg ctgatacttt agctttaata acatctggag ctaccttctt aacttttaaa
     3181 ccaaatgcaa tattatcaaa aacagtcata gttggaaata gcgcataaga ttgaaataca
     3241 ataccaattc cacgcttttc aggttccaaa tgagtgacat ctgttccatt aacttcaata
     3301 cttcctgatg atggatctaa aaaacctacc aatgctctca aagtagttga tttaccacat
     3361 cctgaaggcc caagaaatgt aaagaattcc ccttcatgta tatctaaatt cagattatca
     3421 attgcaacaa aatcaccata tttaatttga atattatcaa atttaatcat ctcactaact
     3481 ccctctatta ctaaaccaaa agcctctctt tatttcttcc ttaaatttag aaataataga
     3541 gagacttgga cataaaaaat aactcttatt tcttattgta cgtattctaa ttcagctttt
     3601 tctacccatt catccaaatg ctttccaaca gcttcccagt caatattttg tggtttcact
     3661 tgatcaacaa atttcttagt atcttctggt agctctttga gggcatcttt attggcaggg
     3721 atagagccaa agtttttact gtactctact tgaatttcag attgaccaaa ccaatcaata
     3781 aattctttag ccaatgcttg cttcttactt gtactcaaaa tcattgtttg ctcagttaca
     3841 aatggaaccc caatttcagg agacatcact ttaaaaacaa cattttgttc tttttgacca
     3901 actagagccc cggaccccca gatcataccg tattgaattg ggctttcttt atctaacgct
     3961 ttaacaactg agctttcacc tttttgaaga gtataggcat ttgcaaagta ttcttttgca
     4021 acttcccatc ctttttctga tacgcctaaa tctccttttt catcaaggta acgaactaag
     4081 atacttgcta gaattgcccg tcctgtacca ccttgaagac cataaattga atatttacct
     4141 ttatacttac tagctaactc tgtccagtct ttaggcattt cttttacatc aggcgcccca
     4201 attaaaacta atggttgaac aatcacagga ttataataat tatctttatc tgataaagat
     4261 tgatcaattt tatctaacca tttaggcttg tactgtacga gtaatttttg atctctaatt
     4321 ttatttgagt caacagcacc aattccaaat accatatctg caactgcatt attcttctca
     4381 gcaataacac ggtctgctaa ttgagcgcca gcgatatcaa ccatttttat attaaaacca
     4441 gcttcttttg ctttagcagt taaccaatca ccacgaccat ttgagactga gttcgaatag
     4501 ataactaatt cttgactttt atcagctttt tcttcagatg aagaagcagt cgtagaattt
     4561 gaacctccag agcaagcagc aagtgtagta agagcaactc ccgttgcaag tacagtagac
     4621 caaactttca tttttttcat gataagttct ccttttttat tattttattt aaatttttcg
     4681 tgatatggaa caaattgtct catatcttca aatacagtat agtcaatacg gtttacagta
     4741 atagttggaa tcttctctaa taaaatttca gttaattctg ctctgacttt agtaaactct
     4801 tcttcctcct cttcggttag aggaatccga agatacccaa ttgaaatatg gaattgatat
     4861 ctatcatgat tagggaaaca aacacctgct ttttctgaga cataagtacg aatttcttct
     4921 aatctctttg cagaagcttc atctgcaggt tcaactagta tgttttgttt tcccatttca
     4981 gttatacgca tatgaatttc ttcatccaac aatggaaaaa tttcaagttg tttagcaaag
     5041 taatcatgta tttcctgtaa aggtgtatct agaggaagat tactgctcca aaactccgtt
     5101 tcacgatttt catggcacaa caattcaatt acagtcatgt gaatagaatt ccttggagtt
     5161 aaagtaaact tatcgataaa tggtaattct ctataacgtg attgaataat atcaacaact
     5221 tccatcaaat cttgtttagt ataaagattt gctacaactg tattcccagg gaaatgatta
     5281 aattccccat tctctttgaa cttaattttt gttaagtttt tcatataaag accttctttt
     5341 ttatatttga catcggtgtc accatgttta cattatacaa tgaaaccgtt tcctttgtca
     5401 agcacttgca aacatttttt taaatttatc tttcattaaa tatgcatttc attaaaaggt
     5461 taagtaattt ttccaaaata cagcactcat atagacagta tcatcaatta tagccattgg
     5521 gattttttga ttgccaattc catgtatctc tacacatgtc ttcaatcgat tttgttgtcc
     5581 tccaatttaa ttccttatat gctttgtctg catttgcata acaagttgca acgtctcctg
     5641 aacgtcttgg aactatttta taaggaatag ggatcttatt aacactttca aatgtattta
     5701 caagttgtaa tacactagtg ccttctcccg agcctaggtt atagatataa acatctgttt
     5761 tttcagatac tttttctaaa gcttttatat gtcctattgc taaatctact acatggatat
     5821 aatcgcgcac accagtaccg tcaagcgtat cataatcatt tccgaacaca cttagttctg
     5881 acagcttacc taccgctact tgtgcaatat agggcatcaa gttgttagga attcctgagg
     5941 gatcttcccc aatcaaacca gactcatgag caccaattgg attgaaataa cgaagcaacg
     6001 caatactcca ttctgaatct gccacatgaa catcttttaa aatttgctca agcatcactt
     6061 tcgtataccc ataaggattt gtcgcacttg tttgcatagt ctcaattaga ggtgactgat
     6121 tgttaattcc atatacagtc gcacttgaag aaaagacaat ctttttaaca ttaaattctg
     6181 acatcacttc aacaagtgcc aatgtactca taatattatt tttgtagtac atcacaggct
     6241 tttgcacgga ttctccgaca gctttataac ctgcaaaatg aattgcagca tcaatcgatt
     6301 cttgttcaaa tacctttctc aatgctggtt tatcacaaac atctaattcg taaaacacgg
     6361 gacgtattcc tgtaattgct tcaatacggt ctagcaccaa gatgctagag ttcgaaaggt
     6421 tgtcgacaat gatgacttcc tttcctaaat ttagtaattc tactacggta tggctaccaa
     6481 tataaccagc tccgcctgtt accaatattg ccatttttgt ttcctcctaa ttaattccaa
     6541 ccgacttaac aaatctcata aacgcttcat gcccagacgg tgtattctta taaactcctg
     6601 catcttccag aactctcgca aacacttgtc ctgcttcgtg ttgaactacg ctattaacct
     6661 cttctttatt aatgcgagga tatttttctt tcaattggtc ggcccattct aaatgataat
     6721 ccgcaattgc gttatcctct cctaaaagat attttccaac ttcttctaac tctggtttca
     6781 aacgaggtgg taatatcgca agtcccatca cttcgattaa cccgatattt tcctttttaa
     6841 tatgttgtac atcttgatga ggatggaaaa caccatctgg gtactgttca gtagtatgat
     6901 tatctcttag aacaatatct aattcatatc tcccgtccac tttacgagca ataggagtca
     6961 ccgtatggtg tgggacatct tcagtcatag caatgatgtc tacttctaaa tctgaatatt
     7021 ctctccactt atttagaatt ttagtagcta aatctaacaa gcgattttta ttttcacttt
     7081 gtaacctaat tactgacatt ggccatttta caataccagc attaacatcc tcaaagtctt
     7141 taaaacgaaa ttcactctca aattttgctt tttccattgg gaaaatatgt ttccctccct
     7201 ggtagtggtt atgactaaga atggagcctc ctgagatagg aagatcagaa tttgaaccag
     7261 caaaatatcc tggcaaaata tcaacaatct ccaataattg ttcaaatgtt ttagaggtaa
     7321 tagccattgg tacatgttga ctatttaaaa atatcgcatg ctcattaaag tataagtagg
     7381 gagaatattg gaatccccat acttcgtcac caagtttcaa tcgaataatt ctatgattcg
     7441 aacgtgctgg ataatttatt cgcccctgat atccttcatt ttccatacat agtaaacatt
     7501 tgggataatt agtggctttt actaattttt cagcagcaat tgtttttgga tctttttcgg
     7561 gttttgacaa atttatcgta atctctagct ctccgtattt agttgatgct cgaaactcaa
     7621 tattcttagc aatagcagaa gttttaatat aatcactatc tttacttaac ttataaaact
     7681 cttcaactgc ttcttgaggt gatatatcat atgaactcca aaaaatatca tttaatcgac
     7741 taggtaaagg aactatgaaa ttcattaact ctgctcctaa acattccttt tcctcgatta
     7801 aatctttaat tttaccgttt tttaaggcga tttccactaa gtaatctttt atttgtttca
     7861 ggtcattttc atcggaaatg cgatcagttc cctcctcacc tattaacgct agtactctat
     7921 ttttcacata tattttgtca atttcattat acattccgta ttcaattact ctatcaacaa
     7981 aattatcaat aattgttttc atatattttt ctttctaatt tatgttccca tattttctat
     8041 acattatcca tttataaatt gattgcgtag tatgagcaat tttatcaagg tgatgaataa
     8101 tatctaaagc accaattact tcagaaacat tcccatcatc ttcaaatatg taattcatta
     8161 ttttcttttc aatatttgta ctaagctctt ctatctcatt ctgtttttgt ataacaacca
     8221 tatctaaaca tccagattgt tcctctctat aacaagatat agccctattc atatgcagtc
     8281 cgataacttc atgaagtatt tttatttctg aaataatttt cttcaaaatt tcattatttt
     8341 gaataatctg tagatttttt aaaatttcaa caattctatc cccaatacgt tcaatgtcag
     8401 ttgatatttt tattacacta ataattcttc ttaagtcata tgaaacggga tgttgtaaac
     8461 aaattaactc atatcctttt ttatcaacat ttagaactga ctcatttatg attaaatctt
     8521 ctttaatcaa ttctattcgt tcttcatttg ataaatattc aaataacttc tcatatttat
     8581 caagcacaga tacccaaatg gtctctaaat tatttgataa ttctataatt tcattttcta
     8641 aatataacct taacatttag gtacctcttc ttaacaaagt tcaatagtaa caattaatat
     8701 tttaaacaat atatcaaaca tcaataacta caatacttgc atcatctttc tttccataga
     8761 ttggatcaat agcagaagaa ttaaatctca tcttaattaa ctcttcaaaa gttttatttt
     8821 gattattttg atagaattca taaaagccat cgctcattaa aacaatttgt tcactagtaa
     8881 catctatttg attaataata gcatggtcta aaaatctctc atccaacgaa cctatccagt
     8941 acccactcgg ttgattagat aattttctga ttttttgtaa aataattttt ttatttaaaa
     9001 cactatttgt accaattgga tcttttatct catttttccc tttttcaaat aagttatcta
     9061 ctctatgatc cgttatttcc atttcgttta ctaacatgac gcagtcacct agcatcatat
     9121 actccaactt tttttctgaa agtttagcaa atataaaagc aaatgttggt aagcgataat
     9181 atagtatatt gaaactagaa tagtacacct ctacttctaa aacattgtta gaaatcgatt
     9241 tgactgtcct gattgatttg tcctattatt atttcatttt attatactct gttaattcat
     9301 atgagtttaa accgatttca tctttaacct cgagtaaagc agtttcaaat atttgtttaa
     9361 gagtttttga ttctttacaa ttaaccgaca aactttctga taaaatatgt acaacttctg
     9421 agactgaata acctatctcc tctttagaat tatataaatc tgtagctcca ccaataatcc
     9481 aaaaatactg attttgtgaa cctacaatat cctcattttc tacggaactt ccttgtatcg
     9541 aacaaatttt atttatcttt accataatac ttcaaccctt ttagtgtcaa aagtaaacca
     9601 attcctgtca ctgttaagaa tagttccata atcttgttcg aaccagtctt tggtaatttt
     9661 tgttttacat ctactatttc tttagattta ttaatatgat tttcagtttc tctgccatct
     9721 ccaactattt tatagtttac ttcttctgtc ttattatctt gtttattgtc gatcttgtca
     9781 ttcatttgtc tattatcttt acttgagtta aactctccgt tcttctggtt actatcaatt
     9841 acattatttg aattagattg tttttcctct ttgttttttt ctttttcgtt tttatcactt
     9901 aaattatttg ttacaatttt gtaaagccca ttctccgtta caatattgaa attaccatcg
     9961 ctatcacgta taacaggttc tttcccattt gcattagatt tgatgaatga tatatactta
    10021 ccggataaat tataaaattg gttatttaaa acggttattt taccctttga atcctcaata
    10081 acaattcctt ctttaccccc gaatatacta ttctctgaga ctactaaatt atcactaact
    10141 cgtaataatt caatatttgg ttgttctgtt tccttagaat tattattaat tacatttttt
    10201 gttacagtaa tatctgatac ttttcctaaa tattctgcac tatcttttgc aactcgtatc
    10261 gcttttgttt taggatcggc aatattaaat atattttcgg cgataaccac ctgtttattt
    10321 aaatctaata ggtctttagt gtttttatag ctataagcat ttactaaagc tgctccgctt
    10381 tctcgataat gtacactctc tcctttaact ttcttatcaa agcgatttcc tttgattaat
    10441 acatcagtga atcctgtaaa acgtacacct gcatacatca tgttatcaaa atgattattt
    10501 aaaattttaa tattagaggg gttctgtgtc gacaatgttt gatagtgtgt gccaattgct
    10561 gttactaatt ccccagattt atcacttttg ccaaaatagg aattttgaat agtcacattt
    10621 tcagattttt tcccatcatc attcaaggca taaggaaaac cttttctagt taatggttca
    10681 atctgaatgc tctccttact tatgatttgc ccatccttca tcgttttggg taaggcttgc
    10741 ccaagaaaac gagaattatc aactaataca tttttcgaac ctgcaatttg aatagcatgc
    10801 ccttgataac tatccttgaa tgttacattt tttatagtta cgttatttga attcccaata
    10861 gcaaatgcac ctgaagaatt tataagtggt agattttttg ctttagttcc ttcttcattc
    10921 aaagcaccgt tcatatcaat cgtaccacca gaataactaa tatcttctgt tgggccccat
    10981 tctacttgcg caccatcatc cgtaaataaa cctgtcataa aaacaatgga agggtgattc
    11041 ttaatattta taccatttag aattgtagct ttctcattca attctaagtg tgtatgactt
    11101 tttaaaaaaa caatttcttt tactaaataa gttccttcag gaaaatatac atttcctcca
    11161 cctagccctt gagctgcagc atctattgca tcttgaattg cttgtcgatc atcatgaatc
    11221 ccatcaccta ccgcaccata atcttttaca cttaaagcag tatcttcaaa ttcttttttg
    11281 ataattctgt cacttataac atcttcctta taactcttat tttcattagt agatgttact
    11341 gtagattcaa ctgttctgtt gtctaattgt gaattggaac gaatagtacc attagagctg
    11401 atgctattaa cacttaacga attatctaaa ccattagtgg ttgaattaga ggcaatcatt
    11461 tcagcagaac gattctgatt aacagttggt gaattatcta aatcattagt aattgcatta
    11521 gaagactctt ttgtagccat cggtgaagaa ctagtaacaa cttcatccga taaaatacct
    11581 tggcttccca aaattgaaat tgccaatagt accgagcaag tccccacctt taatttacga
    11641 atactgaata cctcattagg aacaaaatat ttcatcagaa cctccaattt ttttactatt
    11701 tttaacaatt gattattact tttcttaaaa tagatagaat gacaccgctg tcattatctt
    11761 tatcatatat tttccaaatt gaattgtcaa ggaataacac aagaaaatat taaaatttat
    11821 actcttcgga aatctcttca aactaggtca gtgccgcctt gccctaagtc taggttactg
    11881 acttggtcag ttctatagta gactgaaact ataatagtac acctctactt ctaaaacatt
    11941 gttagaaatc gatttgacta tcccgatcga tttgtcctat tcttatttcc ttttactata
    12001 tctacaacct aaaagcaggg ttttgagcta tctatggcca acttcctagt ttgctcttta
    12061 gccttccatt caaaagtgat gctatctttc ttagcttgaa tataaaatat cccatttact
    12121 atatttaaat ttattgatat gttgtaaatt ataaatgaaa gaacaaatac cttgtcatac
    12181 aagcattcgc cagggatatt taccttaata tcgctcatat ggcggattga aactaaaaca
    12241 ctacaatata tttcttaaat agaccttcta taaaagctag atttaacctc gataaaaata
    12301 gatgcagtgc ttctaaaata ctggaatagg gcatataggt aatcgtagac aagtgtttta
    12361 tagattgtct cgcaggagat ctaatgatgt atagcaagca tcactaaaca tatgggatat
    12421 ttgcgttatt ataatatcaa catgctataa attctatcat gcaaaagaat gactagaaca
    12481 tgaaagacag gcacaaaact ttgaacaata ttctgaaaac aaaaaaaaga cgctagtttc
    12541 cacaatctca ctcatggaaa ctcacgtctt tcaaaaaata gggtgaattg aaaactagaa
    12601 caagacacta gattttctaa atgatgtcta gtaaggattc taaatgctat accaaattgc
    12661 tcacatctta tttcaaacca cgggactccc acaagaaagg aaaatcctat aaaaattctc
    12721 tctctgagga gaaagaggcc tcaactacag gtgtaaacta ttatcaattg aaaacaacag
    12781 tttttacact caattagact ttttaggggc aggatcactt tcgcttgact gtagtttgtc
    12841 atttttttga taaagttagc actttttcag aaactgtttt gaaagtctca atgatatagt
    12901 ctacttcttc atcgcttaat ttagtatgaa gagggagggt aatttcattc tcaaagaagg
    12961 cataggcctt aggatagttc gtcatatcaa atccaagatt cttataggct gtcaagagag
    13021 gaagcggttt gtagtgaaca ttacttgcaa ttcctgcttt agccaattct tggatgatga
    13081 ggttgcgttc ttctaggctt gctccttcta cacgggtgat gtagaggtgg cgtgaagatt
    13141 cgacagtttc agtcttgtgt gccaaaggat ggatgcgaga agctgcaaaa ccactatcat
    13201 agcggtccac aatgtcctta cggcgttgca acaaacttgg atagcggtcc aattgtacca
    13261 aaccaagtga agccatgata tcggtcatgt tgcacttata ggctggtgta acgatatcgt
    13321 attcccatga ccccagttgc atcttggcaa gagcatcctt agtttgcccg tgaagggaaa
    13381 ggatttggaa ttccttgtac atctcttcgt catcaatcac tggattggct ttccaagtcg
    13441 cacttccacc ttctgccgtt gtaaagttct taactgcatg gaatgagaag gaagtaaagt
    13501 cagcgataga accagaaggt tgtcctttat aaatagatcc caaagcgtgg gcactatcag
    13561 agacaatgac aatacggtta aaggcctttt gccacttgct tgaagcggta aagaagtcac
    13621 gttttttctc cacgacttgg aacaaacggt cataatcgca aacaatccct gcgagctcta
    13681 ctggaataat caccttagtt ttctcagtga tagcttgctc aagcaggtca tagtccatct
    13741 caaacgtatc tgcttggata tccaccatga caggggttgc tcccacgtgc gtaatgacac
    13801 tacatgaagc cgtataggtc atggctggaa cgatgacttc atcaccaggt cccacttcca
    13861 aaacgcgtaa aatcaactcc agagcggctg tcgcagagtt gagacaaaca gtcttaggtg
    13921 tctgtgtgta aagagacaag cggcgctcca gttcttttgt tttaggacct gttgtgatcc
    13981 aaccagaacg cagggtatcc actacttcag taatttctgc ttctgtgata tcaggcggtg
    14041 aaaatggaat attgtaattt ggcattgatt tgctcctttt atctgtactc attttcttat
    14101 gactacttta ttttagtacc tcaaacacgg tttgaaacat gattttgatg tccccaaaga
    14161 aactaaactc tcggagatag gcgaggttat agcgcatctt ttcaggaaga acatgctcca
    14221 cataggcctg atcaactgac agacctttct ccgtcatttg actgataatt gtgtcctcat
    14281 ccttgtagtt gatgctggct ggagaggtaa tccctgcttg caagagcaag gttgccatca
    14341 tttcagggct atactgctct gtataacgtg gcacttcagg tcgtgtaccg acaaaggaca
    14401 tctcaccttt aaggacattg accaactgag gcagttcgtc caaacggaca cgtcggatga
    14461 aatttccaac cttggtaatg cggctatcgt tagcagaagt caccagactt ccttttttat
    14521 ccgcatccgt caccatggta cgaaacttcc aaatcttgaa ccgacggttg tactgggtca
    14581 cacgctcttg cttgtaaatc actggccctt tgctatccaa cttgatccaa atgctcaaga
    14641 tgagaaagat gggagaggtc agaaccagta agaccaaggc caaaacccag tccaagcaac
    14701 gcttgaaaat cagcgaaccc ttccttttag agacaagctg gtagtaagac tcaacctcgc
    14761 ttgatttcat ttccacaggc aagtcttccc atttcagcat gctgttctcc tttgttttta
    14821 ttatactatt tgtcaacatt tttcattata ccacaaaatg gaaaaggcgg tgaaagaaat
    14881 ctgtaatttg aaggatttcc ttctagtact caatgaaaat caaagtacag ctttgagatt
    14941 gcagataaag ctgacatggt ttaaagagat tttcaaagag tatcggccat ggcccctgcc
    15001 tgcaaactat acatcttgtg ataggttact cccagagcca agagttcctc atgggttcca
    15061 ctctcgataa tgcgtccctt atccaagaca tagatgcagt tggcatcttg aatagtagaa
    15121 aggcggtgag cgatagcaat agttgttcgg ccctgtctca tcttcgccag agaagcttga
    15181 accaagcttt ctgtttcaga gtcaatattg gctgtcgctt catccaaaat caggatttta
    15241 ggctggctgg cgactgttct agcaaaggca agaagctggc gttgcccagt agagaagctc
    15301 gaaccacgct cggaaacagg ggagtcgtac ccctgaggaa gttcttgaat aaaggaatct
    15361 gcatccacaa aggctgccgc agcctgaacc tgctcatcac tggtttcttg gtacatggcg
    15421 atattggact taatagttcc atgatagagg aagggttcct gcaagaccaa accgatgttt
    15481 tttctcagct cttcttgact gaaatccctg atatccacat catccaagag aactctccct
    15541 gactggaatt cataaaagcg catgaggaca ttgataatag acgatttccc tgaacctgta
    15601 tgacctacaa aggcaatggt ttcaccctta ttaacagaga aagaaatgtc atccagaatc
    15661 ggatgtttac cgtcatatga gaaacacaca tgttcaaaac ggatattgcc ttcttggact
    15721 ttggcttgcc cattttcttg aagaggttca taggtcctct cgtctatcag ggcaaagaca
    15781 cgacctgcag aaaccatagc cgtttgcaga gttgaaaagt tttgcgtcac ctcaatcaag
    15841 gggtcaaaaa ggcggttgat gtactggata aaggcataca tggtcccgac cgttatcccg
    15901 atagaaaaac cacggtagcc aaagtaggcc atcaagactg catagcctag aagtttcagc
    15961 aaactcatgg caggtctcaa aaagagggca tccaaggcta cagaacggtt ggcgtagacc
    16021 aagtgttctt ggttgatttc atcaaattct gcctgcaggc gcttctcttg attaaaggcc
    16081 tgaataatcc tgattccctc gatattctct gccagcttac tattgatatc tgacaagaga
    16141 cttctggttt tctcgatgat tttcactgac ttttttcgat agagattgac caaaaggaaa
    16201 atcaaaggaa gaaagagcaa gactaaagcc gtcaaacgaa aatccagcac caacatggta
    16261 taaagggttg tcagaaagat aaaaactgct gagataaagc tggataaaat cccagaaaac
    16321 atatcactaa tcgtctcggt atcgttggtc aaacgagaaa cgatagaacc tgctggcgtc
    16381 ttgtcaaagt aagacatgcc cagtttctcc atattggcaa aggcatcccg acgaatatcc
    16441 ctaacaatac tgtaagacac gcgcgcaaag agaagattgc ctacatactg aactacagtt
    16501 tgtaggatgt agagaccata gtagaccagc aaaacggtaa cggctagttg gttaagattg
    16561 ctgagatact ggtcgataaa gtgggaagcc acgaggggta tgacactttt aatgaccatc
    16621 gtcgctagga gaaaactgag tgccaaaaag gtcaggagtc cataaggctt gagataagac
    16681 atcaagcgct tcaatacagc ccattgttct tgtttattct gcatcttctt ctcctttcat
    16741 ttccaactgc tgagactggt aggtttgggc ataccagcca tccatcgcta gcaagtcttc
    16801 gtgcgtgcct cgttcgataa tttgaccatt ttgtagaact aaaataaaat ctgcatggac
    16861 aacagcactg aggcgatggg cagtgataat ggttgtcttg tcctttcgcg tctccttgag
    16921 gttgtcgata atcgcatact ctgtcttggc atctacggcg gataaggaat catccaaaat
    16981 caagatatca gggtctaaaa tcatagcccg actcatagcc aaccgttgct tttgaccacc
    17041 agaaagactg actccttttt caccaatcag cgtatcaaat ccttgaggca tgtctacaat
    17101 atcttggtaa actcgggcta gcttagtagc ttcctcgacc gctgaaaggg gcaagttagg
    17161 attgccaaag cggatattgt ctaggattga agtcgcaaag agaaactggt cctgaggaac
    17221 atagcccatg agactgcgaa ggtctgtcag acgatagtcc cgaatatcgt gaccgtttag
    17281 ataaatagta cccttatcca catcgtattc acgcaagagg agcttgatta aggacgtttt
    17341 cccagagcct gtctgcccaa ccaagcccag tgtttgccct tttgccaaac taaagtgaat
    17401 atccgtcagt gtttcctcat tttcaaaagc aaagctgtca atggcatact ccaaacgccc
    17461 attttcaata ccatccagag gaaactcagg gtcttgtaca ggagattcct gagacaaaag
    17521 attttcaatc cgctggtaag aaaccttccc tcgctgagta gtattaaaga ggaaaccgat
    17581 ggccagaaga ggccagacca gcatatccaa atagctgata aaggtgacta gattcccaac
    17641 tgtaatctgc ccttcctgaa ccatcaagga gccaaccaaa agcgttaaaa cataggacga
    17701 accaacaaac aagagaacca tagggtcaaa gagactatca tatttcatgg tttgcaggtt
    17761 cttttggaag gttaattcat tgactgcctg aaaagacttc aactcgtctg cctgataacc
    17821 gaaagacttg gtcactttga tacctgatac ggactcctgt accttgttat tgagttcaga
    17881 aaaagcagct tgggattcgc caaaggcctt atgagtcttt ctccctaggc gactagtcgt
    17941 ataggccatg aaaggtaggg ggagaatggc aacaagaggc atctgccatg agatgctaaa
    18001 gagcatggtc aacaaagtca ccagagccgt gatagaggca tccaccgcag acatgacacc
    18061 gccacctgct aaacgagtca aggcattgat atcattggtt gcgtgtgcca tcagatcacc
    18121 cgtccgatag gtttgataaa aggctgacga catttttgtg aaatgcttaa acaagcgaga
    18181 ccgcatgatc tgtcccaagc aataagaggt cccaaggata tacatacgcc acacatagcg
    18241 caaatagtac ataccaaagg ctgcaagtag caagtaaaat aggctaagaa ggaggtcctg
    18301 ctgagttaat tgccccgatg tgatggcatc aatgactcgc cccataacca taggaggaat
    18361 gagattgagg acggaaacca agaccagggc cacaatcccg actagataac ggcgtttttc
    18421 taacttgaaa aaccaccaga gtttttgaat aatggacata aaatcccttt ctgattgcaa
    18481 atggaaacct gaggccaata ctcaatgaaa atcaaagagc aaactaggaa actagccgca
    18541 ggctgctcaa agcactgctt tgaggttgta gatagaactg acgaagtcag taacctacat
    18601 acggcaaggc gacgttgacg cggtttgaag aaattttcga agagtacaag accccaggtt
    18661 tttcttattc ataagttacg actgtaacag cacccttgtc atattcagca ataaagatat
    18721 tggctacatt gtcatgccct tgtttactga ggttatcaag caaccactct tcgctacgac
    18781 caatcgattc caagacatct acttgaatca caccgtctgt cacaactgga tacttaggat
    18841 tttcatctcc catttgcaca acgatgagtt gcccattttg ctcttgcaca gctcgtttga
    18901 cttgcttcat ctggaaaatc ccttggctac gaagtttgag ggctacatcc gatgcagaca
    18961 aaccaactga acgacaggct tatgggtcaa tattcccatt tttgataagg agagttggct
    19021 taccatcaat caaacgtttc acaaagtgaa cattgttgtt gagctatttg aaagtcaaga
    19081 tcagtttgat taaaatttcg atataattaa gtgtcatttg ttcacatcca ccagttcaat
    19141 tgcgtctgtc ttatacaatt cgactttctc taacaggtac ttgtctggct cacttccgtt
    19201 tagggcacga taatagcgat ctcccacctt gataagtgcg ccatctgtgt ttgtggaagt
    19261 attaacatag acttctgact tgtctactcc caaatctttg gaaacaacct cgatgaaatg
    19321 aagtgaagtt tgaaatttat tgttagaaac ttgattgttt tgataagtcg tgatgctgac
    19381 caaaagcaga gctaaataag gccagagctg aaatcatgac caactcacga aatttggttc
    19441 cttttttatc atggtatgcc ttgaaagcaa aaaaaaactg tcacagctaa tagaacaatc
    19501 ccaaagccaa ccatgatacc attttgctga ccgatttggc tgagtacata gtcataagag
    19561 tagaatttca tgtattttca ctccctttca taaaatcatt cttaattata aacgaaagag
    19621 agtaattttt caaaccatac gttggggaaa tagatctttt tttggtataa taaaatctat
    19681 aatctgaatg aaaaaggtaa ctttatgaaa cttatctcat ggaatattga ttccctaaac
    19741 gctgccctaa ctagtgactc agctcgtgcc aaattgtccc aagaagtcct acaaaccttg
    19801 gtcgctgaaa atgctgatat cattgctatc caagaaacca agctttctgc caaaggacct
    19861 acaaagaaac acgtggaaat tttagaagaa ctcttcccag gctacgaaaa cacgtggcgc
    19921 tcttcccaag agcctgcccg taaaggctat gctggaacca tgttccttta taagaaagaa
    19981 cttacaccca ctgtcacttt cccagaaatc ggtgcccctt ctaccatgga cttggaaggc
    20041 cgcatcatca ctctagaatt tgatgcattt ttcgtaaccc aagtttacac tccaaacgct
    20101 ggtgacggtc tcaaacgctt ggaagaacgc caagtctggg atgttaaata tgctgagtat
    20161 ttggctgaac tagacaaaga aaaaccagtc cttgcgaccg gtgactacaa cgtagcccac
    20221 aatgaaatcg accttgcaaa tcctgctagc aaccgccgtt cacctggatt tactgacgaa
    20281 gaacgtgctg gatttaccaa ccttttggca actggattta cagacacctt ccgccatgtt
    20341 catggcgatg ttcctgaacg ctacacttgg tgggcacaac gcagcaaaac ttctaaaatc
    20401 aacaatacag gctggagaat cgactactgg ctcacaagta accgtatcgc tgacaaggtc
    20461 actaaatctg atatgattga ctcaggtgct cgccaagacc atacaccgat tgtcttggaa
    20521 attgacttgt aaggattttc tatatggact acaatgcggt cattcccgag ttgcttgtat
    20581 cgaatatcga acagtcccgg tccttctact gtggtttact gggttttagg attgaatacc
    20641 aacgtccaga agaaaacttt ctcttgaaga gtgtcaacta atgttagagg agggaacaaa
    20701 ggatcaacta gctgaactga cctacccctt tggtcgtgga gtcaatctct cctttggcat
    20761 aaaggatgtt ccaaaactct attaaagagt gatgaaggca aactatccta tttatcgtcc
    20821 cttgaccaaa agaaagtttc gtgtcagtga tccctatatc tatcctcata aatttgcagt
    20881 tttggatcca gatggctatt ttttaagatt tagcgagtag aataataaaa attgggaaaa
    20941 gtctttaaag ttagaaaaag gcatattgtc aggtgtctaa aaacttgata gtatgccttt
    21001 tatgatggaa aaatcttcta atactcttcg aaaatctctt caagccacgt caacgtcgcc
    21061 ttaccgtagg tatatgatac tgactctgtc aattctatcc acaacctcaa aacagtgttt
    21121 tgaggttgtg gatagcttcc tagtttgctc tttgattttc atttagtata aatgttagct
    21181 tacaatggag tttttgttca ccccctcttc tgtttgttcg ttttttaaat caaaacacta
    21241 acaaaatagt tgatttataa agttatttag tgtaaaataa aaacattggc tcaagcctat
    21301 ttaaaattga atatcgtttt acttgtttat gtcgtgaatt ggcacgacgt ttctacaagg
    21361 tgccggaaca cctaacaata agtaagtcag cagtgagata tggtcgtttt tgccatgcct
    21421 atttggggga cttacttaga gattaagtag gtcctttttg aatattttta atatttccct
    21481 taattagtgc ggacgggagg tgaaattatc ctgtgaataa tttcaggaat tcagggaatt
    21541 tcatccctaa tttttgagcc cctagctctt tcatttctag gcttaggcta aaatagttcc
    21601 ccgaactatt ttactctcaa aaatcccgtc atagacaata acaagattat tgtctatgat
    21661 accactacat cgggaaatat ttgataagac tattacgagc gaagcgagtc ttatcaaata
    21721 tatagtatta gcaaaaggga tcactataga aacatttcaa caacaagtaa attagctttt
    21781 agactttagg aggtcttatg aaattattag aagatcgcat cctcaaggat gggcatatct
    21841 tgggtgataa catcctcaag gtagattcct ttttaaccca ccaagttgac tttagcttga
    21901 tgcgagagat tggtaaggtt tttgcggaaa aatttgctgc tgccggcatt accaaggtcg
    21961 taaccattga agcgtcgggt attgccccag ccgtttttac agctgaagcc ttaaacgttc
    22021 ccatgatttt cgccaaaaaa gctaagaaca tcaccatgaa cgaaggcatc ttaactgctc
    22081 aagtctactc ctttaccaag caggtgacca gcactgtttc tatcgctgga aaattcctct
    22141 caccagagga caaggttttg attatcgacg atttccttgc taatggccaa gctgctaaag
    22201 gcttgattca aatcatcgaa caggccggtg ccacagtcca agctatcggt atcgtgattg
    22261 agaaatcctt ccaagatggt cgtgatttgc ttgaaaaagc aggctaccct gtcctatcac
    22321 ttgctcgctt ggatcgtttt gaaaatggtc aggtcgtatt taaggaggca gatctctaat
    22381 gcaaactcaa gaaaaacact cgcaagcagc cgttctgggc ttgcagcact tactagccat
    22441 gtactcagga tctatcctgg ttcccatcat gattgcgaca gcccttggct attcagctga
    22501 gcagttgacc tacctgattt ctacagatat cttcatgtgt ggggtggcaa ccttcctcca
    22561 actccaactc aacaaatact ttgggattgg actcccagtc gttcttggag ttgcattcca
    22621 gtcggtcgct cccttgatta tgattgggca aagccatggt agtggcgcta tgtttggtgc
    22681 ccttatcgca tctgggattt acgtggttct tgtttcaggc atcttctcaa aagtagccaa
    22741 tctcttccca tctatcgtaa caggatctgt tattaccacg attggtttaa ccttgatccc
    22801 tgtcgctatt ggaaatatgg gaaataacgt tccagagcca actggtcaaa gtctcttgct
    22861 tgcagctatt actgttctga ttatcctctt gatcaacatc tttaccaaag gatttatcaa
    22921 gtctatctct attttgattg gtctggttgt tggaactgcc attgctgcta ctatgggctt
    22981 ggtggacttc tctcctgttg cggtagctcc acttgtccat gtcccaactc cactctactt
    23041 tgggatgcca acctttgaaa tctcatctat tgtcatgatg tgtattatcg caacggtgtc
    23101 tatggttgag tcaactggtg tttatctagc cttgtctgat atcacaaaag atccactcga
    23161 cagcacgcgc cttcgcaacg gttaccgcgc agaaggtttg gccgtacttc tcggaggaat
    23221 ctttaacacc ttcccttaca ccggattttc acaaaacgtt ggtttggtta aattgtcagg
    23281 catcaaaaaa cgcctgccaa tctactacgc agctggtttc ctggttctcc ttggactgct
    23341 tcctaagttt ggtgcccttg cccaaatcat tccaagctcc gtcctcggcg gtgccatgct
    23401 ggtgatgttt ggttttgtat ctattcaagg gatgcaaatc ctcgcccgag ttgactttgc
    23461 taacaatgaa cacaacttcc ttatcgcagc tgtttcaatc gctgcaggtg tcggtctcaa
    23521 caacagtaat ctctttgtca gcatgccgac agccttccaa atgttcttct caaacggaat
    23581 cgtcgtagcc agcctactcg ccattgtcct caatgccgta ttaaatcata aaaagaaata
    23641 agaaaaagag gtgcgagcct cttttttgtg tgacaaaata aaaacatcta cctattcata
    23701 tatgctagtg tcatagtcct gaaaatcatc tgcatcaaga acaatttcac aactcttata
    23761 cttttctctt acaagtcgtt cggcttcatc tggattttca gcctctatac ttactaaacg
    23821 tgataaagtt tctgtaattt ctactgtata ctttttcagt tttagattgc tttccaataa
    23881 ttcacctatt aacaataatc tatgatagga gctatgtagc cactctggca atttatctcc
    23941 tacttcccac ccatattttt ccttcatcaa agctagttgt ttttcgtcac caaatttcat
    24001 attttcagat aaccatctca cacaatcggg atctgataag gtacagacga ttaaacttag
    24061 gttatcgtaa cggctttcag tttcataatc aggccagatg acttttaaga aatcatacac
    24121 ctcttctgat gcaacaagtt gtttcgtttt cataatttcc gatactttcc tctaccttta
    24181 aattctatta tttctttgtc tcttaatatt tgaagctgtt gcctaatctt ttctttgata
    24241 tgattgttct taacaaagat attttttagg tcactttcaa aacgatacat atcttcaagg
    24301 gtaaattctg aaccctctat cttatctata caatttagaa tttctattgt ccaacctctt
    24361 gatgacagag agctcttcct taaaaataaa ccttgcttaa attcttttgt aactttttct
    24421 ggatctctaa cttgtccatc ttgcacaaga aatatccttc ctttagaagg tacttgtgat
    24481 aaatcaatgt tacaaccaat ccaacctgct cgtctagcag ttggtgcaag tggttttctt
    24541 tgaataatcg atttcggtgt aacaaattgc ttcggaagga caagaaagtt atttacctca
    24601 aaattttttg tgtaagttaa aaaaaagaaa ttaggattat tatctgcctg cacacgcttc
    24661 atcatcgttg cataagcacc atcattgatt gttgatgaaa aatttccttt tttgctcttt
    24721 agttcaaact cctcactaca atgattacag taaaaatctg ctacaggccg attattttca
    24781 aaatgattta agggattgtt cccacaatta gggcaataag actgacgata aacccaatcc
    24841 tccgttaaga tacgtgcctt ttggctatta cttttatagg tttctactaa ttctaaatta
    24901 aagtgtaatt ccatttaaaa attcctcact aatatgagaa ctcactcgat ataagcaatt
    24961 aaaatctact ataactagta taccacatat atgtacctat tacatttgta tttcatcact
    25021 ctcttttata tttccttcta acatatctca taaattaaaa atgagtgaga taaatttatc
    25081 ccactcacct ttctttatat acttacccgt ctttcctcag acctttggcc tgtgacaaac
    25141 atggtaaagg ttgctttaca gacatttctg ccctcttgat tggtgatatc cacatccatc
    25201 acacaggttg tacgaccttg atggacacat tctcctttaa tggtcaatac atcgtcgagt
    25261 tttcctgcct taaggtagtt gatagaggat tggagtgtca ccccatcaag tcccagcgag
    25321 ataaccacca aaccactgat ttggtcacat agcgtgaata gatagccacc atgggcattg
    25381 ccatagtagt tgagcgacga gttcactact ttggtcgtca ccacaacgtg accatctctc
    25441 attttttcaa tttcgtaatt ttcaaaggca gatatagcgt caaaatgaaa gtctttcatc
    25501 gtttcctcct gatatttcaa acgacactat gatactactt tttataggac tgtgcaagga
    25561 gaaagctcct agtctagtaa aattccgaca tgttccacaa agcgcataaa ggctgtctgc
    25621 ccttgttctg tctgcttgta gactcctgca tcctcaagta cacgcgcaaa gatagcaccc
    25681 acagagtcct tgacgattgc aagggctttt tctttatccg ttaggtctgg atgttgggat
    25741 ttgagttggt ctgcccactc ctgatgataa tcggcaactg taacagcttc tcctacaaga
    25801 tagctcgcga cttgctccac ttcttctttc agacgtggtg gcaagattgc caagcccatg
    25861 acctcaatca agccgatatt ttccttcttg atatgttgga catccttgtg gggatgatag
    25921 atgccatcag gatgctctgc tgaagtctga ttgtctcgca agaccaagtc caactcaaac
    25981 tgtccatcac gcttacgcgc tattggtgtg atggtgtgat gcggtgtccc gtctgtctct
    26041 gctaaaatct gcacactaga atctgaatac tgacgccatt cctggaaaat cttatcagct
    26101 aagttaatca aatcctcttt ggaatccgaa gtcaagcgta ggacagacat tggccacttg
    26161 ataattccag ccttgacctg ctcaaaacca gcaaatcgga aggtcttttg caagggagcc
    26221 aattccatag gaaatacgtg acggcctccc tgataatgat cgtgagttag aatagagccc
    26281 cccacaatcg gcaggtcggc attagatcca gcaaaatatc ctggaaactg ctctacgata
    26341 gccaacagac gttcaaaact ctgacgacta atggccatgg gacgatgctg gccatctaaa
    26401 aagatacaat gctcattaaa gtaagcatag ggcgaatact ggaaccccca ttcctgacca
    26461 accatttcaa aacggataat ccggtggttg ctgcgagctg ggtggttgac ccgaccatgg
    26521 taaccctcat tctctaaaca aagttgacac tgaggataat tactagcttg caccaacttg
    26581 gctaccgcaa tctctttcgg atccttttca ggcttagaga gattgatggt aatttcaagt
    26641 tctccataat cagatggaac acgataagcg atatttttag caatggcctt gagtttgatg
    26701 taatcatttt tctgactgag ttgataaaaa tcctctatcg cttgctcagg agagtggaca
    26761 taggcttccc agaagtcacg attgacctga ctcggataag gagtcaccaa gtccatcagt
    26821 tcagtaccaa ggatttcacg cgcagtctga ctatcctcaa tcatctctaa tcgaacggct
    26881 tcctcaacta gctggtcctt gaggtcaatc aatttatcca gattggtctc aacttccaaa
    26941 acaccttctc ccactcgtgc caaaacacgg ttggtcaggt agattcgatc catttcctca
    27001 aatgaacttt cagaaatgac atgtgttaca aatttatcta ctaagatcac tatagagcct
    27061 ccttttgact agtcaaggac gcgagtgcca cctgcaactt cagcgatata gaagcttgga
    27121 gcgtatccaa ctacttcctc gtagtgtttg cctacagctt ccttaaaggc ctcaacagta
    27181 tctttttgaa ccaaggcaat ggcacagcca ccaaaaccag cccctgtcat acgagcaccg
    27241 agaactcctt cttgtgccca agctgtgtga acaagagtat ccaattccaa accagttact
    27301 tcataatcat gctccagaga aacgtgtgac gcattcatca aacgaccaaa tgtttccaaa
    27361 tcacctgctt gaagggctgc ttgagcttta agggtacgtt ggttttcaag cacagcatgg
    27421 cgagcacgtt tcaaacgatt ttcatcttta atcaaatagc tatattggtc aacggcccac
    27481 tcgtccaatt cacccagggt ctgaatatcc aaggcaactt gcaattcttc cactgctttt
    27541 tcacactcag cacgacgttc attgtattta gagtccgcca attcacggcg tttgttggtg
    27601 ttcatgataa caacgacatt gtccttcaaa tcaagtggca ccaagtcgta ttctaaagta
    27661 ttggtatcta agtaaatagc acgttggtca gcccccatac caatagcaaa ctggtccatg
    27721 ataccagagt tgactccgat aaagttgttt tctgtttgtt ttccgatttt aaccaaatcc
    27781 aaacggtcta gttttaaatc aaagagatgc tctgccacga ctcctgtcaa gagctccaag
    27841 gatgctgaag aagacaaacc agcaccattt gggatattcc cataaacata aaaatcaaaa
    27901 cctttgtcaa tcacgtgccc agcttcttgc aagaaatgaa gaaccccttt tggataattg
    27961 gtccagttgt gctctttttc aaacttgagg tcagcgagag gcacttcgat aatgcccttg
    28021 tcctcaaagt tagctgagta gaaacgcaag acttggtcgt cacgcttacg agctgcaccg
    28081 taagttccca aggaaatagc agcaggaaaa acgtgcccac cgttgtagtc tgtgtgttca
    28141 ccaatcaaat taatacggcc tggtgaaaag aaggtttggt ctgcttcttg accaaaaaca
    28201 gcaagaaagt ctttgcgaag gacttcagta gtaagatgtt gtgccatatg aattctcctt
    28261 tgactgtccg ttaagccatc ttaacgtgta atcgttttct ttctattgta tccaaggaat
    28321 ttcccaaggt caatcctttt tactaaaatt ttactaaaat atcagtaaaa agaagaaaaa
    28381 tatgatatac taacctaatc aaggaggatt tatggctacc ttaaaagaca ttgcacagct
    28441 agcctctgtc tcaatcgcga ccgtatcccg tgtcctcaac cgcgaccaga gcctatctgt
    28501 tacagaagaa accagacacc gtattttaac cgttgctgaa gagctaggct acaccaaaca
    28561 cctcaagaca ggcgagtccc acaagcccaa gcaaaagatt gccattatcc aatgggtcag
    28621 cgaacaaggg gagctagacg acctctacta ctaccagatt cgcctaggaa tagaaaaaag
    28681 agcccaagag ttggactacg atatcttgcg ctattttaat gaccatcctt ttaccttaag
    28741 cgaggaagtg attgggattc tctgcatcgg aaaatttagc cgagctcaga tttctgcctt
    28801 tgaagaatac caaaagcctc ttgtatttct agacagcgat acactttccc tgggacatac
    28861 ctgtattatc acggattttt acactgctat gaaacaggtt gtcgattatt tcctcagtca
    28921 agggatggac cgcatcggga ttctaacagg gcttgaggaa acaacagacc aagaagaaat
    28981 cattcaggac aagcgtctag aaaacttcaa aaactacagt caagcgaggg gaatctatca
    29041 tgatgaactg gtctttcaag gaagatttac tgcccagtct ggctatgact taatgaagga
    29101 ggccattcag agcttgggag accaacttcc gccagcattt ttcgcagcca gcgatagttt
    29161 agctatcggt gctctccgtg ccctccaaga agctggaatc agcctgccag atcgcgtcag
    29221 cctcatttca ttcaacgaca ccagtctgac caaacaggtc tatcctcccc tctctagtat
    29281 tacagtttat actgaagaaa tggggcgagc aggtatggat attcttaaca aggaagtcct
    29341 ccacggtcgc aaaattccta gcctgaccat gctgggaacc agactgacat taagagaaag
    29401 taccctaaat caagaatagg ataacataaa aaacgaatag agttctaaaa ctcctattcg
    29461 ttttttattc gattacaatc atagacttaa tggtcttacg ttcatccata tctttgtagg
    29521 cttggtcgat atcttccagt ttataacttg aagtaaagac gcgacctgga ttgatatcac
    29581 catcaaggac ggcttttagt aaaaattgct tatcgtatgt tgtagcagaa gctgccccac
    29641 ctgctacaga gatattttgc ataaatgtcg aaccaagagc acgattatta tagtgtggga
    29701 ctcctacaaa gcccatacgc cctccattat gaagaacacc tagcgcctgt tctatagcag
    29761 cctccgtacc aacacattca agtgctgcgt ctgctcctcc accgaggatt tcacgcacct
    29821 tggtaattcc ttcttgacca cgttctgcaa caacagctgt cgcacctgac tccatagcca
    29881 tcttttgacg gtcttcatga cggctcataa ggataatttg tgatgctcca cgcatcttag
    29941 ccgcgatgac agcacattga ccaacagccc catcaccgat aacaacaacc ttgtcccctt
    30001 tttgaacatt tgcaacacgc gccgcatgat agcctgtcgg catgacatct gcaagagtca
    30061 aaagggactt gagcatccct tctgtatagt cagaaggttg accagggatt ttaaccagcg
    30121 cccagtttgc atagtggaag cgaatatatt ctgcctgaaa atcacccccc aaattattgc
    30181 caatatgatt gtcgcaagaa ccgtcaaatc cagcaagaca ggcatcacac tcaccacatc
    30241 catgtgtaaa agggacaatc acaaaatcac ctggtttcac cgtcgtaatg gcttccccag
    30301 cttcttcaac aatcccaatc gcttcgtgtc cactattttt gtgtccagct ttcgtttctg
    30361 gattacggta cctccataaa tctgaaccac aaacgcacgc acgaaccaca cgaataatca
    30421 catcatccgc ttctattatt tgcggacgtt caatgctagc aagtccaacc tgacctgcct
    30481 ttgtatatac tgctgatttc atttaaaatt ttccttcctt ataaagttta attttgagat
    30541 ttaaacgatt taaagctgtc tgtagctgag acaagcgctc ctctaatttt tgcttttcct
    30601 cttctaaaat accaagcctc tcctctctcg tttcatctcc cttttggtag agcgacatat
    30661 agtcaactaa actatctaca gagacacccg ccgaacgaaa acacttaata aattccagcg
    30721 cttcgatatc ctgatcttga aaatcacgaa tcccagtagc agtacgagta atcggtggca
    30781 caagaccaac ccgttcataa taccgaatcg tatccgctga aattcccaac aaatcactgg
    30841 cagatttaat attcacacgc taacctcctc tcatttcatt cactgaattc acgctattct
    30901 aactcactta tcttattata taactttgag ttgactccaa gtcaagcatt ttgtatctaa
    30961 tcgaaaaatt tttatcatta acaatcatat atctggagtt tatacaatgc tcttctctta
    31021 ccaatttttg aaatatttaa ataataaaga aattactcta ttccaaataa gatagtaccc
    31081 aagtattttt cacttttttc taatgttgat gctcataact ccgttccaag tcacacacct
    31141 ttcgcttatg ggtttggtga gtttctaggt cagcatcaat ttcaatggta atattttgaa
    31201 aaccacaatc ttttaggaaa attcgaatag actctttaca agtttccata tgttccattt
    31261 cttttagaca aacatggaca atggcatttt tttccaaagc atccatagtc cagagattaa
    31321 gctgattaag gctggccaca ttgtccaatc gctccaggcc actctttact tgcttgatat
    31381 caagaccttc tggcacagca tccaagaaaa tcttgagtgt agaccaaaaa cgtggaaggg
    31441 cttttgaaag aataaagaaa gaaatgacaa gggacaaaag aggatctagg atataccagt
    31501 ccgtaaatcg aagaacaatc gccatcagga taacagctac ccaccctagc gtatcttcca
    31561 gaaaatgcag actcagaata gactcattct ttgtctttcc cttaccaacc accagactcg
    31621 ctaacagatt gatagtaatc gcaataattc ctaaccagag aatcccctca tcattgactg
    31681 gttgcggatg caaaatcttc gtgacatttt ccaaaatgac tagaacagag cccgttacga
    31741 gaatcacagc tgttaccaag gctcctagca ggctaaaccg cttatagccc aaggtgtact
    31801 gattgtcttc ttcacgattg gagattgttt ctagaaaagc tgatattcca attgcaatcg
    31861 catctcccaa gtcatgcaca gagtcagcaa gaacagcgct agaaccaaat actccacctg
    31921 caataaactc aacaatggca taagtcaaat ttaagaaaaa agccacccaa acagcatatt
    31981 ttgccttcat atttctcatt cctttgttat aatagattta tgaacacctt gttcattatc
    32041 attatccact aaaactcaaa gaaaggatag aagcaaaacg tcagctttat tcagttctga
    32101 acaatttgcc tcaagtgtcc atatgactaa cattgaccgc cgtatcagca aaaccaaaaa
    32161 agccatctat caagctttta tacaactttt gaatgctaag ggctacgagg ccactactgt
    32221 tcaggatatc attgatctcg cagatgtggg acgatccacc ttttactgtc actatgagag
    32281 taaggagctt cttctggacc agctctgccg ctacctcttc catcatcttt ttgaaagaga
    32341 gcaagccatt tcaaccgagg actacctcgc ccacctcttt ctgcattttc ataaaaacca
    32401 agaccatatc accagtctgc tattttccaa aaatgactac ttcctccgtc aactccataa
    32461 agagctagaa caccatgtct attccgtgct agctgataat ttaaaagaag cccaccctaa
    32521 tctgcctact tcttacctcc aacacttggt catgtccaac tttatcgaga cattgacctg
    32581 gtggctcaaa aaaggtcaag atttcacaga ccaggaagtt gtccaatttt atctagacct
    32641 tctcattcct aaaaattgaa tatagagtaa agctcagttg tcttatttct agattactga
    32701 gttttttatc ttttcaacaa caaaagagga cccgccgatc ctctttttca tactataaat
    32761 ccttgattat caactatatc tgttttaatc gaaatctcaa aacagcactt tcaaacatct
    32821 tttcctagtt aagtaaatca gtattctgct tagctgcctt gctccattga taccaaccaa
    32881 ctagactgtt aatgagataa attagatatt tcccttgaat ttgcaggctt tctccccacc
    32941 agagatagat tgaaaagaca ttggtagccg cccagaatat ccactgttca cggtaaacag
    33001 ctgtcatgag gatttgccct accccattgg ttgcatctgt gattgaatca cgatagggac
    33061 gattggcacc aatagactga taaatgaagc caaaggccaa ccaccaaagc acactaatgg
    33121 aaagatactt tgtccagccc ttgccgtcca gtttacgcgc gacaaactcc tgcttttcct
    33181 tcttaaactg tgcctgataa atccaaacta gaagtccaat tggctgcatg actgtgaagt
    33241 aaagtgtcgt cagcacctca ccataaaagc ctttctgtag ggccaaaata aggtaaataa
    33301 cagagttaat caagccaaaa agataattac ttgctcgacc ttccgataca aagattacac
    33361 agataatccc tgtcaagcta caaatcatcc caatccagtc aacaatacga tgttcgtaaa
    33421 ccaactccag ccagagagga aaacttccta aaaccagcaa ataaatccac tgggcaaaac
    33481 tacgatgggc aaagaggtca tcccagatag ccttcatagt tcctgaaaat cctaaatcag
    33541 ccatagccgc aaccatacga cggtaaccac ctgacatttc acctagggtt gttttgatat
    33601 tttcaatttt cttttgcaaa taagtatgca tcatttctcc ttttgttttt aaagagccgt
    33661 gtctggatag actttcggac gcaacgctct attagataat gaactgccta tacacaagat
    33721 ttctaacctt agtcgacatg agctgaaacc tcttatttgt taagtagttc acaaaatatt
    33781 atacacctat tttatgaata gtcaactgtc tttacagtaa aattttagaa aatcatgaaa
    33841 attttctctt tctttccatt ttaagtgaca ttcagtcatt ctcacatcaa aaaagcccag
    33901 acgaaattgt ctgagcattc ttttatctag tcgtttaagg aagttgagtt cagtatgttt
    33961 aaagtctctg tcccatcatt tcttcaacaa accttgttct tggagaaact ccttggctac
    34021 ttgctctgct gacttgcctt caacaccgac ttggtagttg agctggctca tctggttttc
    34081 tgtaatctta ccagccaatg tattaagaac tctttccaac tctggatgtt tcttgagaag
    34141 agcttctttc atgagtggag ccccttgata aggtgggaag agttgcttgt catcttccaa
    34201 gacctgtaaa tcataacgct ccaattccgc atcagtcgaa taggcatccg tgatttgaat
    34261 atcccctgac tgaattgcct gataacgaag agctggctgc atagtcgcca cattgagatt
    34321 gagaccatac attgattgca agcccttatt tccatcttca cggtcgttaa actcaagcgt
    34381 aaagcctgcc ttcagctgcc cttccacttt tttcaaatcc gaaatggtct tcaagccata
    34441 ttcttgagca atctttttcg gaacagctac agcataggta ttttgataag acataggttt
    34501 gagataggct agatgatcct gcttggcaat gccatcacgc gccacttgat aaacctgctc
    34561 tggctcatga ctcaccttgg gtgatggttg aagcaaactt tcagtcaccg taccggtaaa
    34621 ttcaggataa atgtcaatat cacctttttt cagagcttca taaaggaaac ttgtcgtccc
    34681 aaaattcggt ttaacagtcg cagtcatgct ggtattttct tcaatcagca atttatacat
    34741 attagccaaa atttctggtt ctgggcctat tttcccagca ataatcaagt tttccttctc
    34801 tttttgagcc aaaagggctg gactataaga cagacccagt aataaagcca ccaaggcaaa
    34861 accagagaaa atcgtccgca atttcgcttt ttccattact tttagtagga agttaaaggc
    34921 aatagctagc actgcagaag aaagtgcccc aatcaaaatc agactggcat tattacggtc
    34981 aattcccaaa aggataaagg aacctagtcc ccctgcccca atcaaggtcg ccaaggtagc
    35041 cgtaccgata atcaagaccg ctgccgtccg aattccagac atgataacag gcatggcaag
    35101 tggaatttca aacttcttga gacgctccca tctggtcatc ccaaaggcaa tcccagcctc
    35161 ttgcagactc ggatcaattc cattcagccc agtaatagta ttttgtaaaa tcggaaaaat
    35221 cgcataaatc actagagctg tcaatgccgg taaagtccca attcccatca aagggataaa
    35281 gagccccaac aaggccagag acgggatggt ctggaaaata cctgcaatct gcaagaccca
    35341 gtcggccagc ttctcatgat agcgaagata aacagccaag ggaatcgcaa gcaaaatagc
    35401 tagtaacaag gtcaaaagtg acaactgcaa atgttgagat agggctgtca accaatcacc
    35461 aaaacgatcc tgaaaagttg caattaaatt agtcatgaat actacctcca aacaagtctg
    35521 caacaaagtc tgttgcagga gcttttaaaa tagtctcagg attcgacacc tgacgaatct
    35581 ctccatcctg caagacagca atacgatctg ccaactttaa ggcttcatcc gtatcatgag
    35641 tcacaaaaat cgttgtcatc ccaaactctt tatgtaattc ttttgtcaga acctgcaact
    35701 gttttctcga aatagcatcc aaggctgaaa agggttcatc catgaggaga atcttgggct
    35761 gaccaatcat agctcggaca ataccgaccc gttgctgttc tccaccagat agctcacttg
    35821 gaagtcgatg cccatactca gctactggta aaccaacctt agccaaaagc tcttctgttt
    35881 tttgagcaat ttcttcctta gtccaaccct tcatttcagg aatgagagca atattttcct
    35941 caactgttag attgggaaag agagcaatag cctgtaaaac atatccagta gaaagacgaa
    36001 gttcacgctc atcatagtct ttgatgcgct tcccatccat ataaatattt ccatcagttg
    36061 gttccaaaag acggttaatc atcttgagca tggtcgtctt acctgaccca gaaggcccta
    36121 ctaaaaccat aaattcccca tcctcaatct gtaagttgac atctctcaag acatcctttt
    36181 ctgtgtagcg cagtgctaca tttttgtatt caatcattct ttgtcctcaa tttaaaactt
    36241 ccctcgatta gtcaagtctt ctaccttagg catgacttcc ttattatccc aatgctccac
    36301 aattttcccg ttctctaaac ggaagatatc gtactgggca taagcaacgc catcaatctg
    36361 agtctgacca tagctaacca catagtttcc ttgtcctaag agttggaaaa caaagtcaaa
    36421 agtgacacta tattcagcca catagttttt ataagcagca cttccttgtc caatctcatg
    36481 attatgctga atcaaatcgt ctgccacata atcactccac tgctctagct ccccattttg
    36541 gaaaatttct gtcaagaaac ggcgaaccag ctttttattt tctgctttct tatccaaatc
    36601 cttgatttca aaatctccaa aaatttgatc tagttggtca ttttcaggtg ttcgatagta
    36661 gtcaatgaca tcccaatgct caacaatacg accattctca tccgcacgaa aagtatccgt
    36721 cgtcacccat tgagcttctc caccattcag atattgatga acatgaacaa agaccagatt
    36781 gccatcctca atggtgcgga caatcttaat ctgacgctct ggatgacgct caaagaaatc
    36841 tgcaaagaag gctgcaaatc cttctttccc gtcaggaaca cctgtcgaat gttggatata
    36901 ggtatcccct acagactggg cttgagcctc agcaactcgt ccgtcttgaa tggcatggat
    36961 gtataggttg tgagcatttt tcacttgttg tgacatattc taaacctcat ttcccttctc
    37021 tttcaaattc gccaaaattc tttcttgaaa accttcaaat tggtgaattt cttcctctga
    37081 aaatcctttg taaaagatag tatccaattt ctgactgaca cgatgcccca cttctttctg
    37141 ggacttgcct aactccgtta aaactaaata cttcttacgc ttgtcttttc cacacggact
    37201 aacaattaca agcttttgtt cctctagctt ttttatcata gtcgtcagcg tattattcgc
    37261 aagcccagtc gcaagcgcga tatctgtcgc agttgcgcag ccagtttcac tattccataa
    37321 aaccgctaaa atcttgccct gttcacccct ataaagagcc tcaggatctt gactcagtaa
    37381 cttttgaaaa atccgcccat tcaacaaacg aatatgatgg gctagcaaat gaccatcttt
    37441 cataacacct ccaatttatt tcgatatcga aatgaataaa acaattgtaa cactcatcgt
    37501 tctaactgtc aactatttcg atttagaaat aatttttgat aattatccac accaccatac
    37561 tccggctcaa ctaactttta acgagagttt ctaaactcct tcgtcctcca gtctacaaaa
    37621 gccttccatt cgtactatcc tatattttat gaggggacac atttttccta tcagaccatt
    37681 tattttaaag atagaagtaa atcataattg cttccatctg ttcttttata gtatattgaa
    37741 gttagactag agcactgtat cttctaaaac attgatagaa agcgatttga atttcccaat
    37801 caatttgttc gtatttatag catttcgaaa ctggaatagg acaccatgac tgctaaaaga
    37861 tttctataaa ttcatttgat tttcctaatc aatttgttca tatcttattt cattccgcta
    37921 taatttcacc ttaccctatc tttttcgtag cacccttcaa acagcctatc ccctaccgtt
    37981 tgacgattcc tcacttcgct ccacttccat tacagaagtt tcttcactac tatgggctcg
    38041 gctgacttct catgattcct tgttactact atttgaacgc tcacgagata gatcttacaa
    38101 aaaatgcttt gatccacaat ggaatcaaag cattttaaag agttcctcat acataagcgc
    38161 agaagtcgca gttcctctgt acttggcttc ttctcttttg ataaagcgag ccaagttgag
    38221 caactcaggt gctggatgtt tgggatttag gagcaattca cgattgacca ggcctgagag
    38281 acgaactgcc tgcaattgtt catttgtagt aggcagtttt ttagcagtct ctaggagagc
    38341 agcaactaaa tcttcactca aatcatgtcg agcatgattg taaagatctt ttataaggct
    38401 ttctaggttt ggttctgcca tccctaccac ctcccttatg gtttaataat gtttaatcaa
    38461 atcaaccgtt gaacgatcca atttcttcac caaggcttgt aagaaagctt gcgcttctag
    38521 gaagtcatcc attgcataga gggtttggtg agaatggata taacgagcgc agacaccgat
    38581 agttgttgat gggacaccac catttttcag atgagctgca cctgcatctg ttccgccttt
    38641 accacagtag tattggtact tgataccagc ttcttcagcc gttgtcaaaa gaaaatcctt
    38701 catccctggg agaagcaagt gacctggatc atagaaacga atcaaggttc catctccaat
    38761 tttgccttga ccaccgtaga catcacctgc tggtgagcaa tcaactgcga ggaagacttc
    38821 tgggtcaaac ttggttgtag aggtatgagc gccacgcaga ccaacttctt cttggacgtt
    38881 agaacccaga tagagttcat tgccgagttt ttgacctgat aaagcttcag ctagctcgct
    38941 taccatgagg acaccgtagc ggttatccca agcttttgag atgatatttt tttcattggc
    39001 tgtcaaaatt gcagaactat ctggtacgat ggtatcacca ggacggatgc caaaactttc
    39061 tgcctcagcc ttgtccgcaa aaccaccatc aaaaacgata tcggcaatgg ctggcatggt
    39121 tggtcccccc tttccacgag tcaaatgcgg aggaacagaa cctgaaatca caggaatttc
    39181 atgaccatca cgagtcaaga gtttgaaacg ttggctgcta accaccatgg ggttccagcc
    39241 accgatttct acgacacgga aggtaccatc tggcttgatt tcgctgacca taaaaccaac
    39301 ttcgtccata tgagaagcga ccaagacgcg cggtgcatcc acagcttctg aatgtttgat
    39361 accaaaaata ccacccaagc catctgtcac cacttcatcc acatacggtg tcaacttttc
    39421 acgaagataa gcacggacag gcgcttcatg acctgagact gcagcaagtt ctgttacttc
    39481 tttaattttt gaaaataatg ttgtcatttc agttccttct ttctttcatc cattttacca
    39541 ctttttatag gagaaggata gtgggaaggt ggatttctaa gttagtatct tagtcctgct
    39601 ctatcttaga aaaggatagt attctcttgc atgtagtgca aaatctagta aacattccaa
    39661 aattaactcg aatatttatt tccaaacaaa aaaacaatac accatcaaag ttgtttagat
    39721 ttttcatgaa atttacagaa aatagttgac ttccctttct tctttcttta aatatatagt
    39781 tggttgagtt tggaatagta cgctgtagct gctaaaacat ttctagaaat taatttgact
    39841 ttcctaatag agttgttcat atcttatttc aatttactat agtacaaaac tagaaaagga
    39901 aaaaatcatg accaaaacaa ttcttgttac aggtgggact agctacatta gctcccatac
    39961 cgttaaagct cttttaaatg ctggctatca ggtgcatgtc ctcgataatc tctccacagg
    40021 aaatcgagcg gctgtggata gtcgtgctag ctttaaagaa ctggatgttt atgatgctag
    40081 cgccttaaag gcttacttag aagaaaatca gattgatgct gtcctccatt gtgcaggtga
    40141 aattgttgtg agcgaaagta ttgaaaatcc aagtaaatac ttcactgcca acgttgctgg
    40201 tatgaaccaa gttctcaaag tcttatctga agttggcatt caaaaaatca tgttctcttc
    40261 gactgcttct ctctatggaa ataactgtat tgacaagccg gtgactgaag ataccctgct
    40321 cgaccctgtc aacccttatg cagagacaaa actgatgggc gaacgaatga tttactggat
    40381 ggccaatcgc tacgactgga aatatgttat tttccgttac tttaatgctg ctggggctga
    40441 aatggatgct tcaaacggtc tgcgtgtgaa aaatccaact cacatcattc caaatatcaa
    40501 caagaccgca ttgggacaaa atgatagctt aaaaatattt ggagatgact acgatacacg
    40561 tgacggttca tgtattcgag attacattta tgtcttggac cttgcatagg ctcatgttaa
    40621 aggaatgaac tacctatttc aagaagacag ttcttctcaa atctttaact taggaactaa
    40681 aaaaggctat actatcaaag aaatctttaa aactgctgaa gaattactaa attaaaaaat
    40741 cccacacgag attgttgctc gacgtgctag tgacccagcc agtgtcctag cagatgcttc
    40801 aaaagctaaa caatatcttg attggacggc tagctactcc ctcgaagata ttattttatc
    40861 agattaaggt aaaaacattt tagaatagga taacaaagga gaaagtcttg ttgctctctc
    40921 cttgttgtat ttattaaatt atcagaaatt ttattgacag attagaaaaa taatgttaca
    40981 tttatatccg cagatatctt tcgataccaa atctacatga aaggacgggg tatgaaactt
    41041 tctcattatt taattggctt acttctactc ctagtctttc tctctattag cattgggacc
    41101 agtgattttt catggggaaa gctatttgat ttcgaccagc agacctggct cctctttcaa
    41161 gagtcccgtc tcccaagaac tatcagtatt ctcctgactg cctctagtat gagtatggca
    41221 ggccttctca tgcagactat tacccaaaat cagtttgctg caccgagtac agttggaacg
    41281 actgaagccg ccaaactggg aatggtgctg agcctttttg tctttccatc ggctagtctg
    41341 acccaaaaga tgctcttcgc ttttgtttca tccatcgtat tcaccctctt cttcctagcc
    41401 tttatgacca tttttactgt aaaggaaagg tggatgttgc ctctgattgg gatcatctat
    41461 agcgggatta tcggctcagt cacagaagtt atcgcctatc gtttcaatct ggttcagagt
    41521 atgactgcct ggacccaggg ctccttctcc atgattcaga cccatcagta tgagtggctc
    41581 ttcttaggcc tcatcatcct gataaccgtt tggaaattat cccaaacctt caccatcatg
    41641 aatctgggga aagaaaccag cgagagtttg gggatttcct actccctact tgaaaaactg
    41701 gccctctttc tggtggcgct aacgacaagc gtcaccatga ttaccgtggg tggcttacca
    41761 tttctcggag ttatcgttcc caatcttgtt cgcaagcgct atggagataa tctaagtcaa
    41821 accaaactca tggtcgcact ggttggtgcc aatctagttc tggcttgcga tatcctatcc
    41881 cgagttctga ttaggcccta tgagttgtct gtcagtctct tgctaggaat catcggtagt
    41941 ctcgtcttta tcctacttct ctggagaggg ggacgaaaag atgcagacta aaagcaaaca
    42001 taccaagctc ttctggattc tcattattct tgccatcgga gcttgtcttc tctacttttg
    42061 gcccatcact cacttgtcag cctttgcttg gaagttgcgt tcccaaaaga tcatcgttta
    42121 tctcttggta gccatcgcga ctgggatttc gaccattagt tttcaaaccc tgacggaaaa
    42181 tcgcttcctg acgcctagta ttttgggaat tgaatccttc tacgtcctac tacaaaccct
    42241 actactggtt tttgaaagca agtttcttca acttggcaaa tcccctatct tagaattcct
    42301 agtcttactt cttgtccagt ccttcttctt tctcgcctta caaggttact tgaagacact
    42361 gatgaagcaa gacctggtct tcatcctgct gatctgtcta gcgctcagaa gtctctttcg
    42421 aaatatcagc accttccttc aagtcctaat ggatccaaac gaatacgata aactgcaaaa
    42481 tagtcttttt gcctcctttc aacatcttaa cacttccatc ctagccatcg gttctctgat
    42541 catcctcgct ttgacaatct ttttctttcg aaaagcagtc gttctagatg tcttgcacct
    42601 gcaaagagaa acggctcaga tattgggact cgatgttgaa aaagaacaga aagagctcct
    42661 ctggggaatc gtgcttttga cctcaacggc cactgccttg gtaggaccta tggccttctt
    42721 cggctttatg ctggccaacc tcacctacct gattgtcaaa gactatcagc acaagttact
    42781 ctttatagtg gccattctgg ttggatttat tagcttaacc ttggggcaag ccttgattga
    42841 acgagtcttt gcactggaaa ttcgtatcag tatgatcatt gagagtgtgg gtggcttctt
    42901 attctttatc ttactatata ggaggtctcg tcagtgaaac tggaaaacat tgacaaatcc
    42961 attcaaaaac aggatatttt gcaaggcatt tcgcttgaag tcagtcctca aaaactgaca
    43021 gcctttattg gtccaaatgg tgctggaaaa tcgactctcc tctccatcat gagcagacta
    43081 accaagaaag atcagggagt tctcagtatc aaaggacgtg aaatcgagag ctggaattcg
    43141 caagaactgg ctcaagaact aaccatccta aaacagaaaa tcaattacca agccaaattg
    43201 actgttgaag aactggtcag ttttggacgt tttccctaca gccgaggtcg acttagatca
    43261 gaagactggg aaaaaatccg agaaactctg aactatttgg aactgaccaa cttaaaagac
    43321 cgctacatca atagcctgtc aggggggcaa ctccagcgcg tctttatcgc tatggtactg
    43381 gcccaggata cggactttat cttgctggac gaaccactca acaatctcga tatcaagcaa
    43441 agcgtcagca tgatgcagat tcttcgacga ctggtggagg aactcggcaa gaccattatc
    43501 atcgtcctcc acgatatcaa catggccagt cagtatgcag atgaaattgt cgccttcaag
    43561 gacggccagg tctttagcaa gggaagaacc gatcaaatca tgcaggctga cctgctcagt
    43621 caactttatg agattcccat cacgctagct gatatcaata acaaaaagat ctgtatctat
    43681 agctagtaac ataaaagctc aagttagaga accttcagtc tcttagtcaa taagattaag
    43741 agactcccta aatcgttatc acattttaaa aaggagaaat tatgaaaaca tcccttaaac
    43801 tttatttcac tgccctagtg gccagcttct tgctcctact tggtgcatgt agtacaaact
    43861 caagcactag tcagacagag accagtagct ctgctccaac agaggtaacc attaaaagtt
    43921 cactggacga ggtcaaactt tccaaagttc ctgaaaagat tgtgaccttt gacctcggcg
    43981 ctgcggatac tattcgcgct ttaggatttg aaaaaaatat cgtcggaatg cctacaaaaa
    44041 ctgttccgac ttatctaaaa gacctagtgg gaactgtcaa aaatgttggt tctatgaaag
    44101 aacctgattt agaagctatc gccgcccttg agcctgattt gattatcgct tcaccacgta
    44161 cacaaaaatt cgtagacaaa ttcaaagaaa tcgccccaac cgttctcttc caagcaagca
    44221 aggacgacta ctggacttct accaaggcta atatcgaatc cttagcaagt gccttcggcg
    44281 aaactggtac acagaaagcc aaggaagaat tggccaagct agacaagagc atccaagaag
    44341 tcgctactaa aaatgaaagc tctgacaaaa aagcccttgc gatcctcctt aatgaaggaa
    44401 aaatggcagc ctttggtgcc aaatctcgtt tctctttctt gtaccaaacc ttgaaattca
    44461 aaccaactga tacaaaattt gaagactcac gccacggaca agaagtcagc tttgaaagtg
    44521 tcaaagaaat caaccctgac atcctctttg tcatcaaccg tacccttgcc atcggtgggg
    44581 acaactctag caacgacggt gtcctagaaa atgcccttat cgctgaaaca cctgctgcta
    44641 aaaatggtaa gattatccaa ctaacaccag acctctggta tctaagcgga ggcggacttg
    44701 aatcaacaaa actcatgatt gaagacatac aaaaagcttt gaaataagcc acttcaaact
    44761 caatttaata ctcaatgaaa atcaaagagc aaactagaaa actagccgca ggttgctcaa
    44821 aacactgttt tgaggttgca gatgaaagct gacgcggttt gaagagattt tcgaagagta
    44881 taaaattttg acattctaaa acgcatccta tcaagttcac tcaaacctga taggatgcgt
    44941 ttttatcatt ttgaaatcta tttaccccac ctcattcccc ttcttgattt cgtttaaggg
    45001 aaaagcggtc tggaacgggg tccttacctg ttttcgacca gggatgacaa cgtaaaatcc
    45061 gagccaagcc catcaatacc cccttaaaac catgtttttc aatagcctga atcatgtagt
    45121 tggaacaagt cagctcaaag cgacaagagg gtggaaagac tggtgagata aaacgttggt
    45181 aaaagcgcac aggcgctatt aaaattcgtt tcattatttc ttagttacag ccatggtgtg
    45241 tagttggctg atttcttttt tattaagacg acgggattct cctggacgga gtcctgtcaa
    45301 gtctaggtgt ccgaaacgag tccgagacaa cttatctact tggagaccaa cagcttcaaa
    45361 catcttttta acctgatggt tacgcccttc atggatggtc aactgcacca cagagcgatt
    45421 tttgactggg tccactttga gaatttcata aacagctggc ttggttttct taccatcaat
    45481 ctcaagacca cgggtcaagg ggcggagatt gtccttattg accacacctt taacacgcgc
    45541 gacataaacc ttgtcaatct cattacgagg gtgaatcatc tcgtctgtaa agtccccatc
    45601 attggtcaaa atcaagacac ctgatgtatc ccagtccaaa cgacccacag ggtaaatacg
    45661 ctctttgaca ttgggcaaga ggtcgacaac cgtcttgcga cccttatcat ctgtcacact
    45721 ggaaatcaca ccgcgtggtt tgttaagcag atagtagacc ttttcttcgt tgtagatagg
    45781 ttgaccttca acttcgacct tgtcgcctga cttgatagtg gttgctagtt cacgcaccac
    45841 ttggccgtta accgtcacca agccttgctt aatcagctct tctgcttttc tcctactggc
    45901 cacacctgcg tgggcaatat acttattgat tctcatcttc ttctatcctt tcaccaaata
    45961 attggctttc ttgggcttga atctcaagct catcaatcac tggtaattct tctaaatggt
    46021 ttatccccat gtaatctagg aaataatccg tagtcacata gaggttgggg cgccccaata
    46081 cttccttttt cccgtcttcc tttatcaggt caaaagcctg caactttgcc aaggctccac
    46141 tcgagttaac tccacggatg gcatcaattt ctatccgcgt aatcggctgt ttgtaggcaa
    46201 taatggacaa ggtctcaagg gcagcccgag acaagctctg gttgataggc gccttagagt
    46261 attccttcaa aatctctgca aattgaggct tggtcaccaa tctataagca ccacttgtct
    46321 caatcaaagc caaactggaa tctgggtcct tttcatactt ctgggctaat tttcctaaac
    46381 tttgctggat gcctgtcggt ggcagagaga ggagttcagc taactggcgg acccgaatcc
    46441 catcttcacc cgctacaaac aagagcgctt ctatttttgc taaagtactc atctttcctc
    46501 tctatcaagt ctagctttga ggcacttgac tttcttcctt cttttccatg agatagatat
    46561 ctccgaaact ctcctcttgc acgaggatca gctcctgggt tttgattaac tctagggttg
    46621 ccaaaaagag ggtgatgacc tcttggacat tctgggcttc cttgaacaaa tcctgcaagc
    46681 gcaattgatc tcgtccaatc aaggactctt tcacgataat catcatgtcc tcaatcttat
    46741 actcatcccg caagatcgtc gtgtgatttt gtgcaaactc ctcttttttc ttggctagga
    46801 tatttgaaaa agccaaaaag aggtcaatgg tcgtcttgtc atgcacaagc tccgcatctt
    46861 cgtaaatcaa ctctgtcggc gctttggaat aatactgggc ccgttcttgg tgcttggctt
    46921 ccaagtgctc acccaagagc ttgaacttgc gatattcttc gatttgagag aggaggtcct
    46981 gctccaggtc atcccccaag tctgtcactt ctgctacctt cggaaggagt ttacgactct
    47041 taatcagcat gagctgacta gccatgacca tgtactcacc cgtcacttcc agacgcatgg
    47101 cctgcagggt tgagacatag gctagatact gttcgatgac ttccgtaatg ggcacatcgt
    47161 agatatccat ctggtactta gaaaccagat gcaagagcaa gtccaggggt ccttcaaaat
    47221 cttttaattt aatatccatt atctatattt ttctaaggtc aggactgttt ttaatcctaa
    47281 tttttttgca atttcgtaca aatcgacctt gttttctatt tgtcttagaa taaactgttc
    47341 acgtaagact tgagctgata aggatggaaa acctttctcc ttgacaaaag attctaactg
    47401 acgaaaggcc cactgacgag aatagggttt ctctcctctt tcaaaaagat aggtctgccc
    47461 catcaagggt tccaattctg aaagcaaggc cgtgggaatg gtgacaatcc tctgttggga
    47521 agccttgctg attcgcaaca cctgaaaatc cagattgatg tccgcaacct tgatggctaa
    47581 aatctcactg ggcaaaagcc ccatttctag gattaagagc gctagcaagc ggccctctgg
    47641 atggtcgctt tcctgccaaa aagagtctag gtatagaatc tctggctttt ccgtcttctt
    47701 ttcagcttgt ttggctaatt ccaagcggta aaagctgtcc acctctcctt tttgatagag
    47761 aaagtataga aattggttac aggccgaaat ctttcgcttc tgggcgctga tttttagatt
    47821 ggctagctgg gcttggtaaa tcttgagact ggtctcagaa atccgctcac ctaccatgtc
    47881 taaaaattgc tccaaatcat acttatagga ctgcttggaa ttgacagaca agccctgctt
    47941 ttcctctaaa aaggctgaaa tcctgtctct cattggcatc gaatctcata ttccttacta
    48001 aagtcatgca agagggcatt aacggccttg aggatggact tgcgcgtaat aatcccttgg
    48061 aaaataccct ctgcatccac aaccggtaag aaggactcat ctactagctt gtgcaagacc
    48121 tccgtaatgg tgaaatcagg cgaaacaacc gctacgtccg tttttgtcat atgaacgata
    48181 tccgtatccg ccatgatttc ttggctcaag tcatgctcca tctgataggc cataatatct
    48241 ctgagtccaa tcgtcccaac aaactgtttt tcatctgtca caacgggaac acgggtatag
    48301 gtcatctgac tgagcaagag ggtcgcatga tccgcattgt gggtatcaat caacacagct
    48361 agatttttag caggggtcaa aaaagtttcc tcctgcccca acaagaaagt ctcaaactcc
    48421 ttggcaatca tcggctaaac tccttggaca aacctggata cacctcgtga tctcgtgtca
    48481 aaaagtccac tttgaagtaa ctatcatcaa tctccacacg agcatagaga cattctctga
    48541 tggtacctcg tggttggctg atagaacctg gatttagaaa gaggatcttg ccttccatcc
    48601 aagcacttgg cacatgcaag tgaccataga ggcagatagc ggcctcttcc tcctgagccc
    48661 agtagtccaa cttttgaaag ttgaaattga tgtcaaacaa gtgaccatga gtttggataa
    48721 tcttggtcga accaagctca gtcaccagac gttctgggta gccggcgtag aagtccatgt
    48781 tccctttaac aacgcggatg ccctcccaaa gtggagaatc cggacgtagt tcagaatcgc
    48841 cgttatgaaa aacggcatcg actttgccca catagcgatc acggacttct tccacaatca
    48901 agctatcgcc atgggaatcg ctcattacaa tgatggtttg ctttgccatg atggaaatac
    48961 ctccaaaagt ttcttaacgg ctaaggcacg gtgagattga ctattttttt cttccagggt
    49021 taattcagct gatgactcac ctgtctctcc tacaaggaag aggggatcat agccaaagcc
    49081 attttcaccc ttaggttcaa agttaatata acctgaccag tctgcttcaa caactaaact
    49141 ttccttattt gggctggcta cgactagggt tgtgtggaac tgagccgagc ggtccttgag
    49201 ttcaaagacc atggccaatt cgtgcaagag tttggcatta ttttcacggt cagttgctcc
    49261 cacacctgcg aaacgagctg accagacgcc tggtaagcca ccaaggacat cgactttgag
    49321 accagaatca tctgccaaaa ccatcttgcc cgttaattga gaaatggttt ctgccttaag
    49381 gcgggcattt tcttcaaagg tcatacctgt ttctgctact tcaggcaggt cagggtagtc
    49441 attaagattt tccacatcgt agcctaactt atcaaagata gctcggaatt ccttggtttt
    49501 accttcgtta cgagtcgcaa tcaacaaggt ttctctgacc ttgcttgtct caaagaaatc
    49561 atgaacattg accccttctt taggcaattc tacatacaag agttgcccat tttcaaccaa
    49621 gagcagggcc ccatgacgtt gaataacttc caagtttcgt cccatttctt gattaagcat
    49681 gtctaccaca aaggagaaca aacggtaggt agaaccatag cgtaaaacag taactgaaag
    49741 cgggaaacca tactcttcat ctccaaatat tttggagaat tcaaacagag gaaaatctgt
    49801 cttatagtcg ctcaaactgt taacgccacc aaaaatacta taagacccaa cataccagtc
    49861 ccggtcatcc ttatattcat aaattttatt tgtcataatt ctacatgctc cacatgaatc
    49921 tctttttcca gccattcttc accaatttgt gcaaaacttt ggctactggc tgttgtgtaa
    49981 aaacggtgat ggagtggtcc agcatcgcga ccacgattga tttcaaaata attgagtaag
    50041 actgagatat cccgtacgca ctctgcccca ctatcgatga gctgaacctt tggccccatc
    50101 acattttgga taatagggcg aaggagtgga taatgagtac agcccaaaat caggctatcc
    50161 acctttccaa ccaagggacg cagggtttca tagaccacct tcttggtaac actggttgac
    50221 agggcacctg actcaaccaa gggagcaaac ttgggacagg ccaagctctc cacctgtaag
    50281 tcgggatcca gatcatggat tttctgacgg tatatgtctg attgtaccgt catgggcgtt
    50341 ccaatcactc ctattttccc accttgactg gacttgatgg ctgccgaagc tcctggcaaa
    50401 attacaccca agacaggaat atctagttga gccttgattt cttcccagac gaccgcagtc
    50461 gcagtgttac aagcaatgac aatcattttg acatccttgg tcaagagaaa gttgaccagc
    50521 tgccaagtat attcacgaat ttgctcagca ggacgggggc catagggcgc ccgcgccgaa
    50581 tctccaatat agacgatttc ttcatgggga agctggcgca tgagctcgcg cacaacggtc
    50641 aagcccccga cacccgaatc caaaaaacca attggtcgat tatccataca gtcttctttc
    50701 tagtcttttt tctgattgat cgttcattat gattccttgt actgaacgaa ctgaccgaca
    50761 gcttgataga atgtcaacta cctctctctt aatcataatc aaatatcaat agaatgcaag
    50821 gaaaaagtct catccctaaa ccataaccaa catagtgaga agtctggaac tttcatccca
    50881 gacttttcct tatttatttt ttctttttat tgttagcaag ggctgccttt tgttggcgga
    50941 tgatttggtg gtaaacttgt tgtaccttag cttcgcttgg tttttgacca tttgcactca
    51001 aaagagtacg aactgcttca gcattcaaac gtgggttgtc agcaaattct ttttcgattt
    51061 gcttacgaac caagtacatt cctccaagag ctcctcctag aaaagctagc acaatcaata
    51121 caattgctaa aagtaaatcc atcatttttc tcctgtttct ttttgagtcc ctttcattat
    51181 accacaaact agccaccctg accagtttgt tctacacttt caaggatgga atagacagca
    51241 aaaagaaccc tgcttttctg aaaaagaggt ctccttgcta agtttatact caatgaaaat
    51301 caaagagcaa actaggaagc tagccacagg ttgctcaaag caccgctttg aggttacaga
    51361 taaaactgac acggtttgaa gagattttcg aagagtatta atttacataa atagccagtg
    51421 tttgataggg tttgagtaga attttctcag acacttctgc atcttcatag tttgaaatca
    51481 aaatctgtcc attttggtag actgctggca agtcgatttc cacttctttg gcataaaagt
    51541 tattgagcac tagtaacttt tgatcctcaa actggcgttc aaaagcgtag acttgtttgc
    51601 tatcttcaaa ggctggtttg taatttcctt ctgaaatgat tggcatttcc ttacgcagtc
    51661 gaatcaagtc ttgatagaag gtgaaaatca gacctttgat ttcattttct acattgatat
    51721 ctttatagga tttaccaact ttcaaccatg gagtgcctgt tgaaaatcct gcattttcag
    51781 aagtatccca ctgcatggga atacgtgaat tatcacgcga cttagcttga ataatctgga
    51841 aggcttcttg ctgactcttt ccttcttcta agagcatctg ataggcatta agcgattcga
    51901 catccacata atcagtcata gaatcatagt ctgggtcaat catcccgatt tcctcaccca
    51961 tgtagatata aggtgtccca cgtgacaggt gaatgctggc tgctagcatg gtggctcctt
    52021 ctttgcggaa gttttgaata tcgacaaaac ggttcaaggc acgtggttga tcgtgattgt
    52081 tccaaaagag ggcactccaa ccgtctttat cactcatttc cttaccccaa ctatggtaaa
    52141 gactcttcaa ctcttcaaaa tcaaagggag ccaaggtcca cttttgtcca tccttatagt
    52201 ccaccttgag gtgatgaaaa ttaaaggtca tggataattc ctgacgatca ggcgacgaat
    52261 agaggacaca gttttccatg gtggtagaag acatttcccc aactgtcata aagctatcgt
    52321 cagatccaaa agtggcttgg ttcatcatac gcaaatagtt atgaacgatg ggtttgtctg
    52381 tataagctgg cttcccttca ttttcaggac agtccactga aacctcgtcc ttaccgatca
    52441 aattgatcac atcaaatcgg aaacctttga cacccttgtc gcgccagaaa ttaacaacct
    52501 tgaaaagctc cttacggaca ttggaattgc gccagttaag gtcagcctgg gtctcatcaa
    52561 ataggtgaag atagtatttc ccagtatccc cgaaaggcgc ccatgcagaa ccaccaaact
    52621 tagactgcca atctgttggt tggtcttgga tgaagaaaaa gtcttgataa tacttatcac
    52681 cagctagggc tttctgaaac cattcatgct ctgtcgaaca atgattaagt accatgtcca
    52741 gcataaagtc aatcttgtgc tctttaccga cacacaccat ttcctcaaaa tcagccatat
    52801 caccaaaaag aggatccact gccatataat ctgaaatatc gtaaccatta tcccgttgag
    52861 ggcttggata gaatggattg agccagacca tatccacacc tagtttggct aaatagggaa
    52921 ttttttcgat aatcccacgg aaatccccaa taccgttttc agtggtgtct ttgtaagatt
    52981 ttggatagat ttgatagact acttttcctt tatcaagtgt catctgtttc tccttttctg
    53041 ataaaaggga ggaagcagtc ttccgtccct atttgtgcta tttcaattat actcaatgaa
    53101 aatcaaagaa caaactagga agctagccac aggttgctca aaacactatt ttgaggttgc
    53161 agatagagct gacgtggttt gaagagattt tcgaagagta ttagattcgt gtagcgacca
    53221 tgagagatgc tccagcttgg atcgttgtcg gataagttcc aggaatagtc gctgtataag
    53281 catcttggtt ggtgatgata acaggagttt ctgtcaccag acctgcagcc ttaatgacat
    53341 ccatatcaaa acgaatcagt tgctgaccaa ctgtaacgtg atctccttgg actacaagac
    53401 tttcaaaacc tttgccatca agacctactg tatccatacc gatgtggatg agcaattcaa
    53461 ctccctcgtc agagacaatg ccgatggcat gcttggtagg gaaaagaacc gtcactgtcc
    53521 cattaactgg agaggtcaac tcaccttggc ttggttcaat gaccagacct tgccccatga
    53581 cacctgatgc aaaaatagga ttcgtcgctt gactcaattc tttcacttgg ccagttagtg
    53641 ggctgataat ttctaccgaa gtaagttcta ctggttcatg gttcacaaat tctgcttctt
    53701 cttgagcaac gaattctgcc tgcaagttcg tatcgccctc tgtttttgta aagagaccag
    53761 ccttgcggaa gaagaaagtc aagagcattg gaacaacaat cgcaactagc atagttcctg
    53821 caaatggcag catgtattga ggttgaatag agagaatacc tggcaaacca ccgataccaa
    53881 tagaagccgc agttacatta aaagtaacgg ataacatgcc tgcaagggct gaaccagtca
    53941 tcccagcaac aaatggataa atatatttta cgttaacccc aaaaagagct ggttctgtaa
    54001 caccgagata ggctgaaatg gttgcaggaa gtgaaacctg agcctcacgc tcatcatggc
    54061 gatgcatgaa ataataggca aacacggctg agccttgagc aatattagaa agagcaatca
    54121 ttggccatag ggcagtgcca ccagcatccg caatcaattg tgtatcaatg gcattggtca
    54181 tatggtgcag acctgtgatg acaaatggag cgtagagggc accaaaaatt gcaccgaaga
    54241 gccatttaac tggaccagtt aaacctgcca agacaactga tgaaagtcct tgtccaattg
    54301 tccaaccgat tggtcccaaa acagtatgag ccaaaatcaa ggctggaatc aatgacaaga
    54361 aaggtacaaa aatcatagaa atgacttctg ggatatgctt gcgccagaag atttcaagat
    54421 aagacagact caaacctgca agcaaggctg ggataacttg ggcttggtaa ccgatacgat
    54481 taacagtaaa atagccaaaa ttccaaaccc agtttgccgc gatatcagct gctggcgttg
    54541 aagcaaccgc ataggcattg agcaactgag gcgataccaa acagattccg agaacaattc
    54601 ccaaaatttg gctggttccc atcttacgag aaacagacca agtaatccct actggtaaga
    54661 actggaagat agcttcacca ggcaaccaga ggaagtgatt aacccctgcc caaaactgag
    54721 aggattctgt gatggtcttg ccatccaaca tcgaccaatg gacaccttcc aagacattac
    54781 ggaaaccgag gatcaatcca ccaacaatca aggctggaat aatcggagta aagatttccg
    54841 ccagagtggt cataacacgt tggaccacgt tttgattact cttagctgca gacttggctg
    54901 cttctttgga aacaccctca atacctgaaa cggctgtaaa atcattataa aagatgggca
    54961 cgtcatttcc aatgattacc tgaaattgac ctgcatttgt aaaggttcct ttaacagctg
    55021 gaattgactc gatagcttta acattagcct tcttatcatc tcctaaaaca aaccgcatcc
    55081 gtgtcgcaca gtgagttacg gcagtcacat tttctttgcc tccgattgcc tgaagcagat
    55141 ctttggcttc ttgttcaaat tttcccattt gattctcctt atacttgtca aagcaagttt
    55201 gatttgataa gtatattgta aacgatacca aacttgtctg caacttgttt ggtataaaaa
    55261 gggtgttttt ttgtaaattt tctagcactt gtatggtaaa atagatacag gtgttcatta
    55321 aactagacta aaaacctatt taagcaggca aaatgaagaa ataccaacaa ttatttaagc
    55381 aaatccaaga aaccattcaa aacgagactt acgctgtcgg agatttcctt cctagcgagc
    55441 acgaccttat ggagcaatat caagtgagtc gtgataccgt ccgaaaggcc ctgtctctcc
    55501 tccaagagga aggattgatc aaaaagataa gagggcaagg ttctcaagtc gtcaaagaag
    55561 aaaccgtcaa tttccctgta tccaacctaa ccagctacca agaactagtt aaagaacttg
    55621 gactgcgctc taaaaccaac gtggtcagtc tggacaagat tattattgat aaaaaatcct
    55681 cactgataac cggtttccca gagtttcgga tggtttggaa ggtggtccgc cagcgtgtgg
    55741 tggatgatct ggtatccgtt ctggatacgg actatctgga tatggaacta attccaaatc
    55801 tcactcgcca aattgctgag cagtctatct attcttatat agaaaatggc ctcaaactcc
    55861 ttattgatta tgctcagaag gaaatcacca ttgaccactc aagcgaccga gacaagattc
    55921 tcatggacat tggcaaagac ccttatgtcg tttcgattaa atcaaaagtc tatctccaag
    55981 acggacgcca atttcagttt accgaaagtc gccataagtt agagaaattt agatttgtag
    56041 attttgcaaa acgcaagaaa taaaagactg agacaccaga tctcagcctt tttctttatc
    56101 ccaaaactaa ttcatcactg accagacttt ggccactatt tttctggaag agatgcataa
    56161 ggtcttcaac tgtcagatgc tttttctctt ctcccttgac atccaccact atcttgcctt
    56221 gatagagcat aatgagacga ttgccgtact caatcgcatg attcatatca tgggtaatca
    56281 tcaaagtcgt ccactgatgg tgctccacaa tcttttgcgt caagttcatc accatttgac
    56341 tggttttcgg gtcaagtgcc gcagtatgtt catccaaaag taaaagtttt ggtttcatca
    56401 gatctgtcat gactagagtc aaagcctgtc tttgtcctcc tgagagatat tgagtatcta
    56461 cttttaagcg gttttcaaga ccaatattca actccttcaa ggcctcttgg aactggattc
    56521 tatccttctc cttcacgccc caaccaagcc ctctcttctg cccgcgtctc aaggcaatag
    56581 ccatattctc ctcaatcgtc aaacgagaag ctgttcccat cttaggatct tgaaaaacac
    56641 gggcaatatc cttggctctc tttctgacac tcagattttt aatggatttc cctgccagta
    56701 gaaggtcccc ttcgtccacc gatagattgc cagccaagat attcatcaaa gtggattttc
    56761 ctgctccatt tccaccaatc acagagataa aatctccctc ttcaacctct aaatctaatc
    56821 ctttgaggac atggttctca ttgaccgtcc ctgcttcaaa tgtcttgtga atattttcaa
    56881 gtgttaacaa acttgtcata actttctcct cctattcatt tctcaatttc agaccacgaa
    56941 tctttaatct cttttgcaat tctggtgcaa ataaaaccaa agcgagcaag attgcattaa
    57001 agagacgtac caagttttga tctagatttg gaatttcata gatatttaaa ataatcaaac
    57061 ggtaaacaat agcaccgatt ccgatggata ataagcggcc tccaatggtc aagtcgtgta
    57121 tcaagacttc cgcaataatc accgagctca aaccaacaac aatggttcct gtcccagaag
    57181 tcacatctga aaatccatca ttttgggcaa acaaggaacc acatagagca atcaaaccgt
    57241 ttgaaatcat gtaaccaaca atcttcatgg tgtctacatt gactccattg gcctcactca
    57301 tcgggatatt atccccagtc gaacgcaaga ccaagccaat ctctgttttc atcaaaaggg
    57361 tcaagaccaa acaaacaagt aaaaaacagg ccaaactaag tgagaaaaca gttccttcat
    57421 ttgtcagacc caagctcgcc aactgtttaa agacggttgc agaatctccc aaggaaagat
    57481 tgggtacact gcccatgatt ttaatattga ttgaatagag ccctgtcaag gtcacaatcc
    57541 ctgtcaagag agctgggatt ttcatcttgg tgtggagcat tcctgataca agacctgcta
    57601 ccatacctgc cagcaaagca agtaaagtcg caagccaagg atttgcccct gcctgtatct
    57661 gtgatacaac gactgctgcc cccagaggaa aggctccctc agcagtcata tccgcaatat
    57721 ccaaaatacg gaaagtcaag tagaccccaa tcgccacaat cgaccacaac aaaccttctg
    57781 ataaactaga taacacaaaa ttcatcttaa tcctccttat tccttgcctt ctaacttact
    57841 aatatcaatt cccaatgcat ctgccatttc ttgattggta tgcaattcca gtttttcagg
    57901 caactcaact gctatatttt ctggtttctc accttttaaa acacgaatca gcatgcgagc
    57961 tgtctgacgt cccaattctt cataattggt tccgtagtta tacaagccac caacagcaat
    58021 catttctgtt gaaccaccga atactggaac cttgtgttta atagaaacct gcttaactgt
    58081 ttccatggtt aacgaaatga tattatcagt tgggacaaaa accatatcca cctctgccat
    58141 caaactctct gctgccgcct tgacgttatt actgtccaag attgtttttt caacaacggt
    58201 aaagcctttt tctttcagaa gtcgcttagc ttcatccttt tgaacaaccg aattgggctc
    58261 gctctgagta tagaggattc caatcgtttt agcctttggc aacactttct ttatcaaatt
    58321 gatttgggtt gaaatggcat ctgatgactg atcgcttgtc ccagttacat tgcccccagg
    58381 atgttctctt gactcaacca acttggcact gactgggtct gttacagctg aaaagataac
    58441 tggtgtcgtt tgcgtcgtat tggccaagct ctgagcagaa ggccttgcga tggctagaac
    58501 gacatcgctg gattctgcta gttgctggga aatcgttttt agatttcttt gttctccctg
    58561 tgcattttgc aaatcaatct caatattttc cccctcaaca tagccttgtt tggccagctt
    58621 atccacaaat ccttctctag tagcgtataa ggactggtgg gtaataaatt gcgaaatacc
    58681 gatacgaaag acatcttttt cttatctgcc ttcaactgat gcaaactgat cagagaagtc
    58741 aagaggagcc ccactaccaa gagggggcta gtgattttcg aacaactttc ataatgaaac
    58801 tccttctcag aaaagataaa acaaaaaacc gcctagatac tatctaaacg gatacttgaa
    58861 ataacctaac aagttacaac ttagctagtc catttagata ttcatctata tggaccacaa
    58921 tcaaaaatct tagccacata gatacaaaca aattgcttga actgtttgca tccatggtga
    58981 catgtctaca aacactatct aaagtagcta aagtaaaagt tttgattcat agttacggct
    59041 tgtctcttat tcatttcttt ttctgctttc ttttttgatg cttcctgtcc taccaccttt
    59101 ttcatcacct gtcaataaca tttcataatt tttaaaattt ttcaaaaatt ctttcaggaa
    59161 gctttcaaag tttttcaaat cagtccaaca aaaaaagttt tataatttcc ataaaaattg
    59221 acatggaaat tataaaacca ttactagttt agtccttttt gataacgtgc caattcggct
    59281 tggttcgccc aaacatagtg acctggacgg atttctacca tagatggctt atcagtctca
    59341 tagtcgtgtt gacttgggtc gtaaaccttc aagaccttct tacgttccaa gattggatct
    59401 gggattggta ccgctgaaag caaggcttga gtatatgggt gaattggatt gttaaacaat
    59461 tcttctgttt ctgcaacctc tacaataaca cccttgtaaa taactgcgat acgatctgaa
    59521 ataaagcgaa caaccgacaa gtcatgggcg atgaagagat aggtcaggcc gagctctttt
    59581 tggaattttt tgagcaagtt caagacttgg gcacgtacag aaacgtccaa ggctgaaatt
    59641 ggctcatctg caataacaaa gtctggttgc atgaccaagg cacgggcaat accgatacgt
    59701 tgacgttgac cgcctgagaa ttcatgaggg taacgagtca agtgctcagc aagaagacct
    59761 acttcacgga taatattttg aactttctct ttacgttctt cttcatcctt aaataaacgg
    59821 tgattgtaaa gaccttcaga aataatataa tcaacagtcg cacgttcatt caaacttgcg
    59881 gcagggtctt ggaaaatcat ctggattcga cgaatcaatt ccgcagcttg ttcacgcgat
    59941 ttcttaccat taatcttttg accatcaaaa atgatatctc cattacttgt atcatttaga
    60001 ccgatgatag cacgaccaat agttgttttc ccactaccgg actcacctac aagcgagaaa
    60061 gtttctccct tgttgataaa gaagttagca tttttaaccg cgacaaactt cttacttcct
    60121 tcaccgaagg aaatttctaa atctttgatt tctactaatt tttcagacat ttccttcctc
    60181 ctagtcagcc agatgggcaa atcccatttt ttcacggatc ttatcatgga gatttgcaat
    60241 cacagctggt ttttctactt ttggagcatc ctcatgaaga agccaagttt tagcccaatg
    60301 tgtctctgat actgagaatt gaggagcttt ttgttcgaag tcaatctgca ttgcgtagtc
    60361 agaacgcaag gcaaaagcat cccctttcag gtcagtataa agtgacggag gtgttcctgg
    60421 gattgagtaa agatcccctt tatcatcagc aagctgaggc aagctagaca agagactcca
    60481 tgtatatgga tggcgagggt catagaagac ttcctcaacc gttccatact caacgatttc
    60541 tcctgcatac ataaccgcta ccttatccgc aatacttgcc accacaccaa ggtcgtgggt
    60601 aataaagatt gttgtgaaat gatactcgtt ttgtaaagat tttagcaaat caataatctg
    60661 agcttgaata gttacatcca aggcagttgt tggctcatca cagatcaaga catcaggtcg
    60721 gcaggcaagg gcaatcgcaa taacgatacg ttgacgcatt cctccagaat attggaatgg
    60781 gtattcatta aaacgtctat ctgcgtctgg aatgccaacc ttattcatgt agtcaatggc
    60841 caattctttc gcttctttag ctgtttttcc ttggtgtttt acaataactt ctgtaatctg
    60901 actaccaatt gttttaatgg ggtccaaact agtcattggg tcctggaaga tagtcgcaat
    60961 cttagcacca cgaatttgtt cccaatcctt gtgagaagat aaagctgtca agtcctgacc
    61021 acggtagtca atactacctt gggcaatgcg accattttct tcgagcatac ctgtgaaggt
    61081 ctttgtcaaa acagatttac ctgatcctga ctcacctacc aaggctaata cttctccttc
    61141 gactagttca agggaaacgc cgcgaatggc tgtcaatact ttgtcacgaa cgtcaaattc
    61201 cacgacaata tcgcgagcag tcaaaattac atttttttct tttgtcattt ctactcctat
    61261 ctatgtgtac gtggatcact agcatccgct aagttttgac caactacgaa aagggacaag
    61321 gataccaaga caagggttgt caatggaatc cagaacaagt aagcattggt tgttacgttt
    61381 tgtgaataat ccgaaatcaa acgacccaaa cttggcactg taatcggtaa tccaagaccg
    61441 aagaaagaca agaaggcttc gtatgagata aagcttggaa gcatttgagt catggttgtc
    61501 acaataacag ataccaattg aggcatgata tttttggcaa caatcttcaa ggttggtgtt
    61561 cccaaagtac gtgacgccaa gttgtattcc aagtcacgat agcgcaagat ttgcacacgg
    61621 atcatgaagg caataccaat ccatgttgtt acgctcatgg caaaaatcag attccagaat
    61681 ccagctccga ttgagtaagt caagacaata acaatcaaaa gaggtgggat gtttgagatg
    61741 acgttgtaaa cttccatcat gacacggtca actgattttg aaatacccca aataccaccg
    61801 acaaaaacac cgataaccaa gttaatcact gtcgcaatca cagaaatgag gatggagtta
    61861 cgagctccga accagacacc gtcaaagagc gatttaccgt tactgtcagt accgaaccaa
    61921 tgctccgcat ttggcttgat ataacgaaca ctaaagtcgt ttaccttgct gacatcattg
    61981 aaatcaaact tagaaaacat tgggtagatg aaacttatca aaatgatggc taccaagatt
    62041 cccaacatga ctacagttga ttttttcttc ataaattgtt taaacactga tttccagtaa
    62101 gaatatgctg gcgcatcaat agtttcagag gcaaaatcgt cacgttttac aaactgaaat
    62161 ttttctttat cgattgtaga cattatttgc ctcctttctc agtcaattta atacgtgggt
    62221 caataatagt catccaaata tctcccaaaa gacgtgagaa gatagaaata catgtaaaga
    62281 tgaagacaag accaacgacc atagagttat tagatgcttt tacagagtca atcaacattt
    62341 tacccatacc tgggaaggcg aagactgttt cagtaagggt tgcaccaccg ataaccccaa
    62401 taatggcacc aggaattcct gaaaccagcg gaaccatggc atttttaaag atgtgtttgt
    62461 ttgaaatttc tttttcagac aaaccttttg cacgagcgaa acgaacaaag tcttgagatt
    62521 gcaagtcaat catgtaacga cgaatccaaa tggctgtacc aggagcaccc aacaaaccaa
    62581 ggatgactgc tggtaaaacg taagaacgcc aatctccagc tcccaagata gggaatgaat
    62641 ctggaaggga aatagatgat ccaatcaatc gaacgatgta aaccaaggca atcgttggaa
    62701 gagcaagcaa gaaggtcaaa gcccctgttg agaggctatc aatccaagtg ttcttgaaac
    62761 gagccatggc tgaaccaagt ggcacggcaa gagcataggc aagaaccaaa ccaatcaaac
    62821 cagtaatagc agagctgaca atcatagatg gatattggta attactttca gtcgctgtat
    62881 aaggatcatc tttcccatag ctagctactt cacgagagtc agcctgacta ggtgacttgt
    62941 aggttcttga gtaaatattt acagaagacg ttttcttacc tgttgggaac tgaacttggg
    63001 cagttttggt ttgtccttga ccttgagtaa taacctgaag aactggtgta ttagcatagg
    63061 ttgggtaaga gtcacctaaa ttcaagttca caaagttttg atgaacaaat gggaactgac
    63121 tgttaaagta caagagatat ttatgtttag ttcctgaacc gaccaatgac catccgatag
    63181 ctggatcatt ttcaaaacga aggtagcgtt tcaagtctgg attttcaggg tcttggattt
    63241 tatttgtatg gtcaatgtca atcaagttag catagaagtg aaaaacacgt tcaaaaattg
    63301 gaatttcacg agtagcatag aattgaccac tttcagtaaa ttctcccaaa gtccaaccat
    63361 gacctaattg attgatgtac ttttcataaa tagctttatt ggtcgcattt gcttctactg
    63421 ttacagaaga atccatgcta cttgcctttt cttgcaactc tttagtatcg taatactcaa
    63481 tgtagcccat acgctcaaac acagtatttt catagttatc acgtttatca gccgttgtcg
    63541 caattttatt atagttagga tcctgcttga aaatcaattt tcgaggaacc aaggtataga
    63601 taatcgtgta ggtcaaagtc gttactaaga aaatcgaaac caatgaccgc aaaacacgca
    63661 taaaaatata ttttttcata ttatttcctt taaaaatccc aaaagaacct tctcctcatg
    63721 gagagaaagt tctattagaa attatttact tcacatgact tgccaattct ttttgagctt
    63781 tctcatttga ttcagctttt tctttcaacc atttttcacg agctttttca tactcttcct
    63841 tagtcaccgc tttatcttgt aatttcaaat atttgaagta aacatctgac cccttagagc
    63901 ctgtttgcgc agaagctcca gtaaatggaa caattcgtga aagcactggt gctgcaccag
    63961 aagaagccat agcaggaata aagagtgaac tatctgtcaa ccatgcttga gccgctgcat
    64021 atttttcata acggacattc aagtcgcttg tctctttggc agcttcatca actaatttat
    64081 cgtattcttt caaaccaact tgaactactg aagggctatt tggattatca aatcctaaat
    64141 atgtttttgt agtttcactg ctagttgttt ttaaaatatc caggtaagta gatgggtctt
    64201 gatagtctgg cccccatgaa actcctcccg atacatccca atcctcagat gaagcattgg
    64261 cagcatagta agtaatatta aggaattcat cacttgtcat ttgttgaata tcaacaacga
    64321 cattttcaac accaagaact gtttctacag attgtttaaa ggactgaata cgagatatat
    64381 agttttttga tgcttggtct actggaacgt ccagatgaat aggaaactga acgccgtctg
    64441 cttctaaagc tttcttagct ttcgcaaact ctgccttggc cttgtcagca ttgaataaac
    64501 catcctgccc atcagctaaa ttcacacctt tccactcatc accataagca ggaagttgag
    64561 cagcgactaa atcaccaaag gtcttctcac cagctgaaac aaagtctggt tttacaaata
    64621 aattacgaac tgctaaagct gctccatctt taccattgat ttgagctgag taagctgagc
    64681 gatcaagagc aaaattcaag gcttgacgga aatctttgtt aagcaatgcc ttcttagtag
    64741 ctactttctc tgaatctgta gttttagaag tatagttgta actttggcga tcaatattca
    64801 cacccagacc agcaatccca gagcctgatt gtgtgtaata gatattgtcc ttgtattctt
    64861 ctgcaacctt agaatagttg gagctggtag ggtaaagacg ggcataacta taagctccac
    64921 tagtgaagtt acgctctagc gactcctgat ctgatccatc atagtaagct agattgatag
    64981 tatctaggtg gacattttct ttatcccaat attgctcatt ttttacaaac tctacagaag
    65041 attttgcagt caaccctttc aacaagaatg gaccattata aagcaaggat gtcggatctg
    65101 ttggtttagc aaaatcgctt ccttttgatg tttcgaattc ttcattcaga ggccagaaaa
    65161 tagaataggt caacttagag ttccagaacg gttcaggctg gttcaaagtg tattgtaacg
    65221 tataatcatc aaccgccttg acaccaactg ttgaaaaatc tgttgaagtt cctgatagat
    65281 aatctgccaa gcctttaacc gaattttcag ctaaatacat agcttctgat tttttatctg
    65341 ctgcgtgttt taaaccgttc acgaaatctt tagccgtcac ctctgcatat tcttctccat
    65401 cagaggtaaa ccatttaacc cctttacgaa tcttataagt gtaggtcaaa ccatccttag
    65461 agacttccca atcctctgca actgcaggag caagattacc gtaattatcg ttagtgaata
    65521 aaccatcaat cccatttgaa gtcactactg ttgtactatt tttacttgaa atcaggtagt
    65581 ccaaggtttc tgggtctgct gtataaacat agccataagc tttaggggct gatgaatcag
    65641 atgattttga agaactgcat gctgcaagta cacctgctgc taataaaaca agacctgctg
    65701 tagcaaatac acgatttttt ttcattttct actcctctgt ttatgtgaat tatagattga
    65761 caaccattat atcacattat ccattaaaaa tcaaacaaat tttcagaata tttaggcttg
    65821 ttggcacaaa tttttcattt tttttgaata tatgattcaa attgtcgttc gaagtgtcaa
    65881 agactacagt gaaaatagga aatttgacac agaaattttg gagcttagga agacatacag
    65941 taaaatgaaa tacggacgga acaatgtgat tttggaattc aaattaaatt ataacaatat
    66001 tgtagaagta tcattctagt attcaagatt cagtttacta tgtcttttca caccaacctt
    66061 attccgaatt caattacttt cgtgatttac acatatagat taagactatc ttttatactt
    66121 taaaatttct cgctaccttg tccactatat gctcctcgct atcacgtttc tattcatagc
    66181 ctacgatttc actattgctt tctctgacaa ttcttatttc ctgcgtcaga cttaaaacga
    66241 tctatcccca gaccatttta atccgctacc tcacgatagt caggcttggg gagcgctatt
    66301 gtattcaccg gtagtggatc cctacagagg acttacacct cagatgcacg acatgcccat
    66361 cgtataaaaa aatctcctac ccaaggtaga agatttcaaa cttataaaac ttaatccgtc
    66421 atgtccgata ccaacattcg atgctccaat ggaatactgc acataactag caagaaaata
    66481 aagcctgact gaatccagaa gagagccaag tcaaaaattc cgtgcacagc aaccactgta
    66541 aggaaagata gataaaggcc gataatcgga cgtttccccg actcctgact catatccatc
    66601 atcaagcgaa caggagcaac agaagacaaa actaataaaa tggtacccac aattccgtaa
    66661 ctcaaaatcg tatcaatata aagactgtgg gcatgttcat gataaggagc atgtatccga
    66721 ggataagagt gcatataggt caatggccct tcaccccaaa aaggattttg cttaaacaag
    66781 gccatcccag catcccagat agaaatgcgt tcttccatag aagagtctaa agtacccatt
    66841 cgaactccca aatcactaga aaagaggaaa ctcaaaccaa tcgcgaagac cccaatacta
    66901 agccaaaagg ccttccagtt tttaatagtc gtaaagagat agataattgc tccagcgata
    66961 atagcaggaa aggcagttcg attttgagta aagttcaaac caaagagatt aacaaagcct
    67021 gcaatcacac agaatacttt caaccaattc aacttggtcg ttgtaaacag atagaaagca
    67081 atcataatac agaaacaaca aataattcca taataattag gattaaagaa ggtcacttct
    67141 gcccggttct gatgccacac ctgcatattg ggtgaaagaa aagcatagtt aaatttcttc
    67201 acaatttgga aatgttctaa actggcaaaa gcagctgaca agacactacc aaacaagacg
    67261 aactgcaaaa tcaatcgaaa gaatttatgg gataaaatcg actgatagtg caaaaagaaa
    67321 atagtaaata gaaacattcc tactgaagcc acaagaccca tccaattttg tgcaagaatg
    67381 gatataacag tactatagct aagaaaaaga agcagcatcg gatgctcccc cattttctga
    67441 agaatacttt tcatgtctcc tgtaaaaatc aaactgataa tatataaaca gagtacaact
    67501 acaaaaagat aaaagggtaa aaagatactt aggataattc ccaataaaat cagctcttta
    67561 ctagacaacc ccttcagctt ttcaataaag cctattgatt tcaaaatgaa tcctttctct
    67621 ccaaatcagc tgattcagat aatagtaagc tatcctatat tgtaccactt ttttagcaat
    67681 ttgaaaacaa aggaaacgtt ttccaaaata aaaaccctat tttatccacc atatcaaggc
    67741 ttcaaaatga tacttcaact ccattctcaa ttacccgata agtctgattt tgcaaatcaa
    67801 tttctactac tgctgttacg gacttatctt tattttgacg tttgattaca atgctgtgag
    67861 ctgttggtgt ctctatctca gtagtccctt ctagatcaaa ggcttctgaa cggttacgga
    67921 aagaaaatag attgagaagg gccttcacaa caggtcgttg cacttctttt gctatttcct
    67981 cgttgctata gtaatgacga ttaatatttc gaccttcttt agtttcttct aataatttca
    68041 agtcattctt gcctgctaat agacccacat agtaaacctg aggaatacct ggggcaaaag
    68101 cttgaattag acgagcgaga aaatacttga catcatcatc tccaagcgct gaatagtagg
    68161 ttgaattgat ttggtagata tctaagttgt tatactcggc actagagtac ttacgtttga
    68221 cattggctcc aaccttatag agttcatttg aagcatagtc aatctcctca tcggtcagga
    68281 tatccttgac atctactact ccaatcccat catgggtatc tagcatcgta aattgcttca
    68341 tcgggctcat ctttaaccac ttagccaaac gctctgttct ggaactgtaa agagtataaa
    68401 gtgtcaccat tggaagagca aaatcataaa catagtaatc atggtctgct attttaaact
    68461 gaatcgaata gtgttcatga atctcaggta aaagctctgt cccatactca gcagcgatat
    68521 ctcgaacttt gtccaataaa tcccaaatat ctggttccac aaagaaatca ttagtatcca
    68581 atttcttcac tgcataagca aaggcatcta gacgaatcaa atcacaccca ttacttgcca
    68641 agtgctgaat ggtcttacgg ataaattcca tagttacttc tttggtcaca tcaagatcaa
    68701 tctgctcctc accaaaggta ttccacaaat gttccactga accatcttca aacacaatct
    68761 cttgctttgg tgcacgatcc ttacgcttgt aaattaaatc tacatcagac tgtgtcggac
    68821 ggttttctgg ccaaaactta tcccagttta aaaagagagc tttaaattca ctggcttcat
    68881 gtttttcttg atagtcctta taatacttgg attgacgaga aatatgatta atcataaaat
    68941 caaacataag ataatatttc tcacctaaac gcttaacatc ctcccaatca ccaaaagctg
    69001 agtccacttc gtcgtagtca actggcgcaa atccacgatc acctgttgat gggaaaaatg
    69061 gtaaaaggtg aactcctcca atagcatctc caaaatgctc ttccaaatta tcatataagt
    69121 ctttaagatt atttccaagg ctatcagaat aggtaatcaa catggtttta ttttgaattg
    69181 gcatcattac tctccttttt ctaattgaag ccaagtctca tatgatctgg cttcataaat
    69241 aaaattcatt ttaaatctct atttatcatc aaactcgtac taatatagac tgtgataaac
    69301 aaagtactac tttcttgttt tctgcataga attatcaaca agctaaactc ttcctctgtg
    69361 tcaaagacta tagattccat gagctcttcg aaaatctctt caaaccacgt cagcttcacc
    69421 ttgccgtact caagtacagc ctgcggctag cttcctagtt tgctctttga ttttcattga
    69481 gtattacttc actgccccgt tgctcattcc tgaaatgata tggcgttgga agaagagata
    69541 gacaatggtg atactgataa tgccgaccac gtaagaggca aagcttggtc cgtagtcgtt
    69601 gaaatattgg cctgcgtagt tgtattggaa caaaggcaga gtccacattt tggaatcccg
    69661 gttcaagaca aggagtggca acatgaagtc attccagaac caaagggcat tgataatcat
    69721 ggttgtcgca tgcatcggtt tcatcattgg gaagatgatg cggaaatagg ttgtaaattg
    69781 attagcccca tcgatctctg ctgcttcatc cagactttct ggaatcgaga ttttgatata
    69841 gccaacatag agaaagaggg tctgtggaat cgcataggtc aagtagagca agatcaaacc
    69901 aaaggtatta gccaaaccga gtttactcat cataaccgta atcggaatca tgatgacttg
    69961 gaaaggtacg aagattccga ggattaagag ggtatacatg atggtaaagg cttttctttt
    70021 actcatattg cgagcgatgg agtaggctgc catagggata aagatcatta ctgcaagtaa
    70081 agacaagaca gtgatgacga cagagttcca ataatagcct ccaatcccat cagctaagag
    70141 acggctaaag ttgtcccatg tgaagttggt tggaaagcca aagaaattat ctacaatatc
    70201 cttagtgggt ttgaaggaac taaagagggt agcaaggagc ggcactaaaa tcagaaccga
    70261 tcctagaatc aatagaatgt atttgccaat cagggctttt ctttcatctt gtttcatcat
    70321 gcttctcctc ttaaatttca aatttcttag atactctcaa ttggatgatc gaaatcacta
    70381 caattaagag gaacaagatt acggcaatgg cattggcata accgaattgg ttgtttttaa
    70441 aggcatagtt ataaaccaag agcccaagtg aggttgtggc attgtttgga ccaccaccgg
    70501 tcatggcaaa gacttggtca aaggcagtca gcccaccttt tagggctagg ataaagacca
    70561 tagagacact tggtagcaag taaggcaatt caatgttcca gaaaacttgc ttgctagtcg
    70621 caccatcaat ccttgctgcc tctgtaatct cagttggaat agattgcaaa ccagctagga
    70681 agatgatgat gggcatagcc accccttgcc aaagaaggac aaaggcagcc gcaaagattg
    70741 ctccccactt agtccctaaa agactggttt ggagaaattc aatatgaagg gcattcccaa
    70801 tcgctggaag accgtagttg aagacttgct tgaagatcaa agccactgtc aaaccagata
    70861 aaacagctgg gaagaagaac caagcacgga agaaggtttg gcctttgatt ttagagttca
    70921 agacacgcgc aatgaagatc ccgagtgcaa tctcaccaac caccatggca atcgtaatga
    70981 ttgcggtaaa gccaatcgca ttcatgaatt ttggatccat gaagaggagc ttaaagttgt
    71041 ttaagccgac aaatttgtag ttataagtca atcctgtcca gttggtaaaa ctgtaaaagg
    71101 ctccttgaaa catcggcaca tagaagaaaa ttgcttgtaa caagaggggg atgaccacaa
    71161 aagcccatgc ccaatatttt tgtaatactt ttttcatagt ctctctactc ctaatccaca
    71221 tccgctttca tcgggttaaa gaaggcattc aaatcattga ccatgccttg tttatcaccg
    71281 gtcaagacat agttcatggt caaggtatgg aagtctgctt cactggtcca gtattgttgc
    71341 aaccagacca agtgacgatc cgtaaaggca tattcggtca taccagcaag cggtgaatct
    71401 tctcctgctt gtttgacccc ttcgatcgct gttggagatc cgtccacatc gtagtatttt
    71461 tgcatgactt ctggacgggt catatattcc acaaaggcat tggcttcttt tggatgtttg
    71521 gtggtggctg agatagacca tgccaagtct cccgcaccaa cggttaagct ttgtcctttt
    71581 tcttttcctg gaatcatgaa ggtcccaatc ttaaagttcg gtttttgttc attaatcgct
    71641 gtgatcgccc aagacccatt tggtgtcatg aggacatccc cacgtgcgaa ggctccgata
    71701 acatcggtat agccagcacc ttcccagttc ttttgcttag agccattgat gcgaaggatg
    71761 tccatgacct tgatatcatc tttcataatc ggatccgaca atttaatggc atttggttga
    71821 gaataacgaa ggtattgatt tgcttctttt cctccacctg ttgctgtcgc aaaggctaat
    71881 tgattgtaac cattgagtgt ccaagcatct gcacctgcaa ttccaaatgg tgtttgtcct
    71941 ttagcaacga tatctttgac taactgttca aattcatccc aggtttcagg aaccttcaag
    72001 cccagttctt cgaatttatc tttgttgtag taaattccat aagcattagc tgtaaaagga
    72061 acgttgtaaa ctttttcgtt tacagcatat ttttcagcgt agccattttt cacgcgtttc
    72121 aggtagtctt tgttgctcaa atcttcaaaa acacctgctt ttgcccattc ttgcagttcg
    72181 atggactgtg ggtaaatatt gaccacatca ggcacatctc ctgcgagaac gcgtgtcttc
    72241 aatacttcac cagcatttgg tacattgacg actttgacct tgatcttagg gttttccttc
    72301 tcaaaatcac gagtgatttc ttccaaggtt ttggtcattt cttttttctg gttgaaatac
    72361 tcgatggtca ctgtgccatc cgcagattta ccatagttgg agcaagcgcc gagcccaaac
    72421 aaagctaaac ctgtagttgc aagaagttcg atttttttat accattccat tagaaagcct
    72481 cctttataaa tttatacacc cttattgaac tgcaccccaa aagttagaca gaataaatct
    72541 aacttttggg gtcagtacat atcatagttt tctaaaaata tactgtctac tcaaaaaatc
    72601 tccttgggat aagataacag ttaagcccgc atacattagt tctgcacctg agtaaacttc
    72661 gccattttcc tgtaatttat atagtccctc ttcatccaaa tcttttaatt ttaaagttgt
    72721 ttccatggtc tctacaacag ataaaacgcg aacgtaggtt acaatcgttt gatttccgta
    72781 attaaattgt acagctgctt cattggatgc agtatcagga ttaattagtc tatactgctg
    72841 tcctaactga actactggtc gtaattcttt atacaagttc acctgattag caatcgtagc
    72901 tttctcttca tctgataaat ttgtcaaatc aagctcatag cccaaatttc ccatcattgc
    72961 tacatggcca cgtgtttcta atggtgtcat tcgtcccatc tgatgattcg gtactgctga
    73021 cacatgagcc cccatagaaa tggttggata gagataggat gaaccgtatt gaattggtaa
    73081 acgtgcaatg gcatcagtat tatcactagc ccagacttgt gggaaatagc gtatcatacc
    73141 aagatcattt cgtccaccac caccagagca ggactcaaag agaatatggc tgtgcttctc
    73201 tgtcagataa gaaacgagtt cgtaaagtcc cagcatgtac tgatgagatt gcatctgtgt
    73261 ctctagataa gttaatccat tccctagctt agtgatattg cggttcatat cccatttaat
    73321 gtaatcaatc tcatgataag ataggagttg atctaagaca cttttcaagt attctactac
    73381 ctgaggattg gcaagattaa gtactaattg attccgagaa taagtatgct cataatcagg
    73441 aacctgaata gcccagtcag gatgttgacg atacaaatca ctatctacag aaatcatttc
    73501 gggttctaac caaagtccaa actgcaaacc tctttcatgg atagctgaaa tcagactttc
    73561 tagacttcca cccagttttt cctcattaac aacccaatca cctaaagcac gattatcatc
    73621 aaaacgattg ccaaaccaac catcatctaa tacaaaaagt tcaatgccaa ctttcttagc
    73681 ttcatctgct aactctaaca gtttttctct ctgaaagtca aagtaagtag cttcccagtt
    73741 attgattaga attggacgtt cttttttaga aaattcactt agagtaatgt gcttcagtac
    73801 aaaattctga ctttcatgac taataccagt taatccctga tctgaatgag tcactaaagc
    73861 taccggtgtt tcaaagtatt cctcaggggc taacttccaa gaaaagtttt ctggattaat
    73921 gccaatagcc acccgaactt cattcaattg atttttttga acaaaagctt caaagttgcc
    73981 actatacatt agttgaatag caaacacatt cccagcatcc tctgtgactc cttgttcgca
    74041 tagtagaaga gctggtgttt gagcatgacc agaagcacct cggtttgaac taatcgaaaa
    74101 gattccttgt tctacctgtt gacgtctaac agtcttttca cgagcataag caccctgcag
    74161 agttactatt tcgtaatctg cagctggaaa atcagccata aaagaaaaat ctttatggat
    74221 gacaacttcc tgattactat tattatctaa tttactgtag ctagcaatag tcgcatcatt
    74281 attaaaagta gtataataca aagtcagact aagttgagcc ttagaatctt ctaacattaa
    74341 gacaagagtc tctgtatcgt ccatgctatg tggagaaggt aagccctgtg gaccattctg
    74401 accttttaaa atctttgctt ctacaaatcg aaagtctgtt acttcagtta cactatgctg
    74461 aacctgtata gttggtttcc taaaatctcc taagccatgt tgtccaaaaa tctgtcgctg
    74521 agtatctaaa ctaaaggttc gattagtagc cgttggattt cctgaaaagg catggtctcg
    74581 ttcataaaca ctattggaac ctttatagtt cttaatagtc tttcctaaat gtttcaaaag
    74641 taagtagcca tttcgatttt caataatcaa acttagattt ttactctcaa cataaaatag
    74701 attattctct atcctaactc ccatttactt cacctcatca ctttattgat tatattttat
    74761 cacctgaaat cgctttccaa aatagaaaaa tgtctcaaga atatggtaaa atgttaggta
    74821 ggaggtagca catgctagtt ttttcagaat accagactgg aacaattgac cttgccctaa
    74881 gcttttatgg atatgaggaa tgcacaccta attactcttt tggtccagcc attcgtgata
    74941 catacgtcct acattacatt agtaaaggac aaggaaaatt tcattacaag ggtaaaattg
    75001 ttgatttaaa agaaggagat ttctttctat taaaaccaga ggaactaacc ttttatcaag
    75061 cagatagtaa agaaccttgg gcctactact ggttaggaat cactggaggg aaatcccctg
    75121 attattttgc tctttctcaa atttctgatc aatcctatct catccaatct gaaacttgtc
    75181 atacccagac tactgcaaaa ctcatctcag acattgtccg cttcgctcag attacaaaat
    75241 caagtgaatt agctcaactc catatcatgg gacaacttca tgaactgatg tttcatctgg
    75301 gaactattgc tcccaatcag aaaaaaaaga atatttcatc aacccaccaa ctctatcttg
    75361 aatgcaaacg attaattgat agccactatc ctcaatcact tacaattcaa gatttagcaa
    75421 aagaactatc cgttcacaga agctacttat caagcgtatt caaagaattt aataccttat
    75481 cacccaaaga atacctactc tacgttcgaa tgcaccgagc tagacaactt ctcgaaaata
    75541 cccaagagtc catcaaggta attgcatact cggtaggttt ttcagatcca ctccattttt
    75601 cgaaagctta taaacaatac tttaatcagt ctccaagtca tacaagaaaa gaatactctc
    75661 aataccaact agtgagaaag gcaacattat gaaatcctac caagctgtct accaaatcct
    75721 atctaaagaa accgactata tcagcggaga aaaaatcgca gaaaaactat ccctaagccg
    75781 aacatcaatt tggaaagcta tcaagcgact agaacaagaa ggcattgaaa ttaatagtat
    75841 caaaaataga ggatataaac taatgaatgg tgaccttatt cttccagaga ttctagaaga
    75901 aaatcttcca attaaagtca gctttaaacc cgaaacaaaa tcaacacaac tagatgcaaa
    75961 agaagcaatt gatttaggcc atgaagcaaa tactctctat ctagcttcct atcaaacagc
    76021 aggccgaggc cgttttcaac gttccttcta ctcaccacaa ggtggaattt atatgacact
    76081 ccatcttaaa ccaaatctcc cctatgacaa attaccatcc tacacactac ttgtagctgg
    76141 agctgtctac aaagccatta agaacctaac tttaatagat gtcgatataa aatgggtcaa
    76201 tgatatctat ctaaacaatc ataaaattgg aggaatcctt actgaagcaa tgacctctgt
    76261 agaaactggc ttagtcacag atatcattat tggagtaggt atcaatttca ctattaaaga
    76321 cttccctcag gaattaaaag aaaaagctgc cagcttattt aaagctacag ctcctataac
    76381 aaggaatgaa ttgatcatag aaatctggcg tgctttcttc gaaacaccag cagaagagct
    76441 attataccta tacaaaaaac agtcattcat tctaggaaaa gaagtcactt tcacactaga
    76501 gcaaaaagac tacaagggac ttgctaaaga catctcagaa aatggaaaac ttttagttca
    76561 atgtgataac ggaaaagaaa tctggctaaa tagtggcgaa atttctctca atagttggaa
    76621 gtaaaataac acaattataa tataaacgat ataaaaataa cttcagatta gtaattcaat
    76681 taagttttac ggatctgaag ttttattgtc tctaaaaaca aaaaagagag ttacaaactc
    76741 tcattaaaac ggagaataag ggattcgaac ccttgcgcca gttacccgac ctaacgattt
    76801 agcaaaccgt cctcttcagc ctcttgagta attctccaat taatgggcac gagtggactc
    76861 gaaccaccga cctcacgctt atcaggcgtg cgctctaacc acctgagcta cgcgcccaag
    76921 ttaaaaaact tggtaatttg aacaaagttc aaagcgggtg acgagaatcg aactcgcgac
    76981 aacagcttgg aaggctgtag ttttaccact aaactacacc cgcataaata ctatcaat
//
LOCUS       DAVHKZ010000003        70107 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000003 DAVHKZ010000000
VERSION     DAVHKZ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 70107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.003"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(389..1249)
                     /locus_tag="VVO74_000315"
     CDS             complement(389..1249)
                     /locus_tag="VVO74_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU5694411.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1265..2542)
                     /locus_tag="VVO74_000316"
     CDS             complement(1265..2542)
                     /locus_tag="VVO74_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU5694412.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQSLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(2535..3086)
                     /locus_tag="VVO74_000317"
     CDS             complement(2535..3086)
                     /locus_tag="VVO74_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5694413.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(3102..4361)
                     /locus_tag="VVO74_000318"
     CDS             complement(3102..4361)
                     /locus_tag="VVO74_000318"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU5694414.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGVSIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRYLRGTSVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            complement(5516..5674)
                     /locus_tag="VVO74_000319"
     CDS             complement(5516..5674)
                     /locus_tag="VVO74_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694415.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(5684..6994)
                     /gene="obgE"
                     /locus_tag="VVO74_000320"
     CDS             complement(5684..6994)
                     /gene="obgE"
                     /locus_tag="VVO74_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU5694416.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(7058..7192)
                     /locus_tag="VVO74_000321"
     CDS             complement(7058..7192)
                     /locus_tag="VVO74_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU5694417.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSSL
                     "
     gene            complement(7251..7427)
                     /locus_tag="VVO74_000322"
     CDS             complement(7251..7427)
                     /locus_tag="VVO74_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU5694418.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(7458..8783)
                     /locus_tag="VVO74_000323"
     CDS             complement(7458..8783)
                     /locus_tag="VVO74_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU5694419.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFSDVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDVNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(8799..9842)
                     /gene="cpoA"
                     /locus_tag="VVO74_000324"
     CDS             complement(8799..9842)
                     /gene="cpoA"
                     /locus_tag="VVO74_000324"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU5694420.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKEIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(9957..10286)
                     /locus_tag="VVO74_000325"
     CDS             complement(9957..10286)
                     /locus_tag="VVO74_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU5694421.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(10300..11409)
                     /gene="rpoD"
                     /locus_tag="VVO74_000326"
     CDS             complement(10300..11409)
                     /gene="rpoD"
                     /locus_tag="VVO74_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU5694422.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(11412..13172)
                     /gene="dnaG"
                     /locus_tag="VVO74_000327"
     CDS             complement(11412..13172)
                     /gene="dnaG"
                     /locus_tag="VVO74_000327"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU5694423.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KSASPHQDLYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(13262..14020)
                     /locus_tag="VVO74_000328"
     CDS             complement(13262..14020)
                     /locus_tag="VVO74_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694424.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(14017..14883)
                     /locus_tag="VVO74_000329"
     CDS             complement(14017..14883)
                     /locus_tag="VVO74_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5694425.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(14952..15956)
                     /locus_tag="VVO74_000330"
     CDS             complement(14952..15956)
                     /locus_tag="VVO74_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU5694426.1"
                     /translation="MKNKRLIGIIAALAVLVAGNLIYSSMNKSEVQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSIGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(16069..16286)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16369..19065)
                     /gene="ppc"
                     /locus_tag="VVO74_000331"
     CDS             complement(16369..19065)
                     /gene="ppc"
                     /locus_tag="VVO74_000331"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU5694427.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(19085..20314)
                     /locus_tag="VVO74_000332"
     CDS             complement(19085..20314)
                     /locus_tag="VVO74_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU5694428.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(20458..20696)
                     /locus_tag="VVO74_000333"
                     /pseudo
     CDS             complement(20458..20696)
                     /locus_tag="VVO74_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(21099..21996)
                     /locus_tag="VVO74_000334"
                     /pseudo
     CDS             complement(21099..21996)
                     /locus_tag="VVO74_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398059.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
     gene            complement(22021..25104)
                     /locus_tag="VVO74_000335"
     CDS             complement(22021..25104)
                     /locus_tag="VVO74_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU5694429.1"
                     /translation="MIEFGRRSLYFSKLVRSKAKMIEFDIPLESHLPISEDAQKSFLG
                     ALAIVADTARKYFEVYINRKSFNLQLKNQLHNAAEYFDALLVSGLGNSAEYQDYIAIL
                     GTTAYYLCDYNGSSRVMINYISDDIQLLEDCMTLIKVFIDVVTDELFLNHTPIEGKYS
                     SELNTLVESYRNYILSKTEFSIDIYRDLQDKVYRNGSDFSVIIVNCLLAVVCKKINSS
                     STKLLPEFSGLDFSLWQDYIQSTGSIKELWPSQIELGKQGIFSGKSGIVQMPTSSGKT
                     ASINLTLRSAFYSNRIDNALIVAPFRALCREIYRDINAHFVDENNVIVSEVFDLPEIP
                     QDFSIFNDGKKRVFILTPEKLLFLLRNHQSFIDEIGLCIFDEAHLFDDPSRGTNFELL
                     LSTVKQIFPKGIQKILISAVIPNSEAINRWFNEDGVIVSNNSIKTTEKRVAFSDLNGS
                     NEQLYFIDPITFEEEFFVPRTVSVSELEQLGKERKQKVFPELTNANDISIYYGTKLIN
                     NGGVGIFCGRKDTVNVILRRFIDLNNRNYDLTDFLKNSDRSEVEKIGNLIGQNLGYDS
                     VEYTCSQLGVFSHHSGIPMGIRIAIEYAFSKSKINNVVCTSTLAQGINLPIKYLIISS
                     VYQAGDAIKVRDFQNLIGRAGRAGKYTEGTIILTEPNIYKSPKNKWKKQNYKALLNPI
                     NTEGCQSNILSIIQFKSVVPTDYRFAPIKFDFWNLIKERFDSSVDYRTKINNILSKLK
                     RKNSLYFKDFNSKIDQIDNTLIAIENYIASMYATELETDSLAENTFGYFLGNEEEKEK
                     IKELFILIKSKIITSSVETEIIAKNSIGLYQSELLKEWVQENKTSILSCEKEEELLGV
                     LTKKIIDFSNNKEMRKLSIENLNYISQLWIKGISYFQILESCTEKSISIEKRGKSKPI
                     DMSDIISICDNGLGYETSMVLNAINNILEKLVGEELDVLTMLIKRLKYGLPLEKEINI
                     YELGFSDRIVVQVIGQEINSVSKNQIRNEIKQKSARLEDKLSDFPSYYTQIINEM"
     gene            complement(25101..25910)
                     /locus_tag="VVO74_000336"
     CDS             complement(25101..25910)
                     /locus_tag="VVO74_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1837 domain-containing protein"
                     /protein_id="HEU5694430.1"
                     /translation="MEKMHSYIKYLTQEDPIITDEGKQIEILHLDIQDDPEIFEDWAK
                     QFRRNYCSDDELAEMIGFMNISPKEYLENFKLPSDSGIGLSTMSGDFGEILVSDYLQY
                     IEEYVVPRTRYDSKVNKNTSTQGSDVLGYKQDSSNVSNDEVVVIEVKSSASDSSSSKA
                     KNKLQEAINHSDKDFERFSTSIVASYLRLKKSNSDQANVVERFLNITDKPFNVIYGAV
                     AVYSNQSYDIDVIKTVVSKNHRDFQKLRLLVIHSNELMKFIRELYSKASEV"
     gene            complement(25894..26670)
                     /locus_tag="VVO74_000337"
     CDS             complement(25894..26670)
                     /locus_tag="VVO74_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU5694431.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQSIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQENGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYAINPNPARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAAEVLQEYLFGKWSKVEEEMLKVGEERMRDMSKSNGKDA"
     gene            complement(26670..27146)
                     /locus_tag="VVO74_000338"
     CDS             complement(26670..27146)
                     /locus_tag="VVO74_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5694432.1"
                     /translation="MIGKNIKSLRKTHDLTQHEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(27591..28046)
                     /locus_tag="VVO74_000339"
     CDS             complement(27591..28046)
                     /locus_tag="VVO74_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694433.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(28321..30060)
                     /locus_tag="VVO74_000340"
                     /pseudo
     CDS             complement(28321..30060)
                     /locus_tag="VVO74_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
     gene            complement(30223..31107)
                     /locus_tag="VVO74_000341"
     CDS             complement(30223..31107)
                     /locus_tag="VVO74_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU5694434.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVIANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(31219..32073)
                     /locus_tag="VVO74_000342"
     CDS             complement(31219..32073)
                     /locus_tag="VVO74_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU5694435.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEATYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(32131..32889)
                     /locus_tag="VVO74_000343"
     CDS             complement(32131..32889)
                     /locus_tag="VVO74_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU5694436.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDVRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(32950..33138)
                     /locus_tag="VVO74_000344"
     CDS             complement(32950..33138)
                     /locus_tag="VVO74_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU5694437.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(33460..34026)
                     /locus_tag="VVO74_000345"
     CDS             complement(33460..34026)
                     /locus_tag="VVO74_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694438.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPGENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(34294..35973)
                     /locus_tag="VVO74_000346"
     CDS             complement(34294..35973)
                     /locus_tag="VVO74_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU5694439.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSDKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIIEELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYKEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            complement(36065..36226)
                     /locus_tag="VVO74_000347"
     CDS             complement(36065..36226)
                     /locus_tag="VVO74_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694440.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQDMKNSFD
                     MAKTQIETD"
     gene            complement(36910..37632)
                     /locus_tag="VVO74_000348"
     CDS             complement(36910..37632)
                     /locus_tag="VVO74_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEU5694441.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEKDIEIDKEREGEIDKKSTP
                     IFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEE
                     DKDKLRQKGLNKKMNYDVGESL"
     gene            complement(37806..39026)
                     /locus_tag="VVO74_000349"
     CDS             complement(37806..39026)
                     /locus_tag="VVO74_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000785359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEU5694442.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDKSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEKWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLK
                     GWIGNLLDNLSTAYEKFKDIERDKVIDNPKLFNLTNYLLTYSEIQKEKSKYLKGYAKT
                     NKEKYDFKKLTSAYSYLRKNNIETIGQLQTKIETLKSNSYRLNKKEKESIQKQIKKYK
                     DLSKNKDKTKEKGK"
     gene            complement(39336..39653)
                     /locus_tag="VVO74_000350"
     CDS             complement(39336..39653)
                     /locus_tag="VVO74_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEU5694443.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKD
                     EIT"
     gene            complement(39709..40134)
                     /locus_tag="VVO74_000351"
     CDS             complement(39709..40134)
                     /locus_tag="VVO74_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU5694444.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            complement(40522..41316)
                     /locus_tag="VVO74_000352"
     CDS             complement(40522..41316)
                     /locus_tag="VVO74_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694445.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
     gene            complement(41316..42323)
                     /locus_tag="VVO74_000353"
     CDS             complement(41316..42323)
                     /locus_tag="VVO74_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU5694446.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(42323..43330)
                     /locus_tag="VVO74_000354"
     CDS             complement(42323..43330)
                     /locus_tag="VVO74_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU5694447.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(43320..44345)
                     /locus_tag="VVO74_000355"
     CDS             complement(43320..44345)
                     /locus_tag="VVO74_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU5694448.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(44738..44956)
                     /locus_tag="VVO74_000356"
     CDS             complement(44738..44956)
                     /locus_tag="VVO74_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5694449.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(45247..45480)
                     /locus_tag="VVO74_000357"
     CDS             complement(45247..45480)
                     /locus_tag="VVO74_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HEU5694450.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCN"
     gene            complement(45694..47325)
                     /gene="rlmD"
                     /locus_tag="VVO74_000358"
     CDS             complement(45694..47325)
                     /gene="rlmD"
                     /locus_tag="VVO74_000358"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU5694451.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(47399..48373)
                     /locus_tag="VVO74_000359"
     CDS             complement(47399..48373)
                     /locus_tag="VVO74_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU5694452.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSAHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(48447..49061)
                     /gene="pmp23"
                     /locus_tag="VVO74_000360"
     CDS             complement(48447..49061)
                     /gene="pmp23"
                     /locus_tag="VVO74_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU5694453.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(49061..50035)
                     /locus_tag="VVO74_000361"
     CDS             complement(49061..50035)
                     /locus_tag="VVO74_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU5694454.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(50043..51299)
                     /locus_tag="VVO74_000362"
     CDS             complement(50043..51299)
                     /locus_tag="VVO74_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU5694455.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPKTELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(51361..51792)
                     /locus_tag="VVO74_000363"
     CDS             complement(51361..51792)
                     /locus_tag="VVO74_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5694456.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIC"
     gene            complement(51794..52396)
                     /locus_tag="VVO74_000364"
     CDS             complement(51794..52396)
                     /locus_tag="VVO74_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU5694457.1"
                     /translation="MMDRIRQELEKGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLSEISFEEA"
     gene            complement(52380..53219)
                     /gene="prmC"
                     /locus_tag="VVO74_000365"
     CDS             complement(52380..53219)
                     /gene="prmC"
                     /locus_tag="VVO74_000365"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEU5694458.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(53219..54298)
                     /gene="prfA"
                     /locus_tag="VVO74_000366"
     CDS             complement(53219..54298)
                     /gene="prfA"
                     /locus_tag="VVO74_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU5694459.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEELAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(54295..54885)
                     /locus_tag="VVO74_000367"
     CDS             complement(54295..54885)
                     /locus_tag="VVO74_000367"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU5694460.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            55009..55191
                     /locus_tag="VVO74_000368"
     CDS             55009..55191
                     /locus_tag="VVO74_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU5694461.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            55328..56701
                     /gene="mnmE"
                     /locus_tag="VVO74_000369"
     CDS             55328..56701
                     /gene="mnmE"
                     /locus_tag="VVO74_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU5694462.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMKFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(56748..57683)
                     /gene="dapA"
                     /locus_tag="VVO74_000370"
     CDS             complement(56748..57683)
                     /gene="dapA"
                     /locus_tag="VVO74_000370"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU5694463.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(57739..58815)
                     /locus_tag="VVO74_000371"
     CDS             complement(57739..58815)
                     /locus_tag="VVO74_000371"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU5694464.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDMDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(59157..59229)
                     /locus_tag="VVO74_000372"
     tRNA            complement(59157..59229)
                     /locus_tag="VVO74_000372"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(59194..59196),aa:Thr,seq:ggt)
     gene            complement(59329..59838)
                     /locus_tag="VVO74_000373"
     CDS             complement(59329..59838)
                     /locus_tag="VVO74_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU5694465.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(59836..59932)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            59961..60392
                     /locus_tag="VVO74_000374"
     CDS             59961..60392
                     /locus_tag="VVO74_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU5694466.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            60474..60851
                     /gene="mscL"
                     /locus_tag="VVO74_000375"
     CDS             60474..60851
                     /gene="mscL"
                     /locus_tag="VVO74_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU5694467.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(60893..61987)
                     /gene="hemH"
                     /locus_tag="VVO74_000376"
     CDS             complement(60893..61987)
                     /gene="hemH"
                     /locus_tag="VVO74_000376"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU5694468.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGMRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENIKMPYLIKKMLEKAGKLPKE"
     gene            62141..63364
                     /gene="pepT"
                     /locus_tag="VVO74_000377"
     CDS             62141..63364
                     /gene="pepT"
                     /locus_tag="VVO74_000377"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU5694469.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(63400..63732)
                     /locus_tag="VVO74_000378"
     CDS             complement(63400..63732)
                     /locus_tag="VVO74_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694470.1"
                     /translation="MDALLDQLSANSKDKTALLESTKAILVLNHQIQSKASASEETSP
                     ARNAEANGDNTSAENQPNATAESNIETASDENKPSNTRDSKPAESTSENKTTESSTTT
                     GNQEKPVE"
     gene            complement(63737..64030)
                     /locus_tag="VVO74_000379"
     CDS             complement(63737..64030)
                     /locus_tag="VVO74_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694471.1"
                     /translation="MSKANQLLERIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHFYLESNNGSDADF"
     gene            63995..64216
                     /locus_tag="VVO74_000380"
     CDS             63995..64216
                     /locus_tag="VVO74_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694472.1"
                     /translation="MDSFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(64353..64562)
                     /locus_tag="VVO74_000381"
                     /pseudo
     CDS             complement(64353..64562)
                     /locus_tag="VVO74_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809565.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad protein"
     gene            complement(64683..64825)
                     /locus_tag="VVO74_000382"
                     /pseudo
     CDS             complement(64683..64825)
                     /locus_tag="VVO74_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262445.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(64859..64999)
                     /locus_tag="VVO74_000383"
     CDS             complement(64859..64999)
                     /locus_tag="VVO74_000383"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU5694473.1"
                     /translation="MLEITLKSPYQFAHILFQSTIVPHGGHYHFIPESDLSAGELAAA
                     KV"
     gene            complement(65043..65603)
                     /locus_tag="VVO74_000384"
                     /pseudo
     CDS             complement(65043..65603)
                     /locus_tag="VVO74_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(65829..68948)
                     /gene="phtE"
                     /locus_tag="VVO74_000385"
     CDS             complement(65829..68948)
                     /gene="phtE"
                     /locus_tag="VVO74_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEU5694474.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNLADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(69158..>70107)
                     /locus_tag="VVO74_000386"
     CDS             complement(69158..>70107)
                     /locus_tag="VVO74_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU5694475.1"
                     /translation="EIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIK
                     KDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMP
                     YNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPN
                     ERPHSDNGFGNASDHVRKNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSAD
                     NLYKPSTDTEETEEEAEDTTDETEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAME
                     TLTGLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
BASE COUNT        20583 a        14448 c        11402 g        23674 t
ORIGIN      
        1 atcattcata gaactactat accatatttt gtttcgcagg aagtataata taaaaaaata
       61 aatttaagat tggcaataca aacgttaaac agaattccat ttctcttttt agaatcaaaa
      121 cgacaatatt gtggaatctc tacaggaaca atagactgcg acactaaaat atcctccctt
      181 agttttactt tactaatagt atataggagg agagccctga atcctagacc ctttgttatg
      241 atgcgcttac aaacagagtt ggaaaaaatc ttaaaagcag aaaaacgcat gatatcagcc
      301 cctaacactt gatacaatgc gttttattat gaaaagatct actggatttt ttatcaaaat
      361 aaacttccag tagtcttttc actttttatt aataagttcc ttcttcacct tggctagtca
      421 agataacagg tccatctttc gtaatgacaa attggtgttc atactgacat gacaatccac
      481 cgtcaatggt cttatgcgcc caaccagttt tcatatctgt atcaatttcc caatcgcctg
      541 tattgatcat tggttcaatg gttaagacca ttccttcacg aagacggagt ccacgacctg
      601 caataccata gttaggaacc attggttctt cgtgcatagt tgggccaaca ccatgaccaa
      661 ccaaatcacg cactacaccg taaccacgac tttcagcgta ttcttgaata gccgcaccga
      721 tatcaccgat acgatttcca acaacagctt gctcaatacc cttgtacata gcttctttgg
      781 ttacatccat caagtttttg acttcttcgg acggtgtacc aacagcataa gcccaacatg
      841 agtctgctaa accaccagaa tagctctgag tgtatttttt catttgttca acattgttga
      901 agtttaattt tgagacattc aggtcggatt tagcaatggg acctcccaaa accatatcaa
      961 ctttgagcaa atcaccatct ttcaagatat aatgacgagg gaaagcgtga gccacttcat
     1021 cgttaagaga gcaacaggta gcataaggat agtccatcat ggcaccgtca accccaatct
     1081 gaagtggaag gaaattttct tctttacaac gacggcggac atattcttca acttcccaca
     1141 tatctacgcc tggcttaatc aaatcacgta agcctatatg aatacttgct agaaaatcac
     1201 cagccttgtc catagcttcg atttcacgag ctgattttaa tgttatcatc ttttctccta
     1261 gtttctaatt aattttaaca gtcacatttg cttttgaaac aatctggtga ccatgataaa
     1321 tatcgtaatc aattatagct gaccgtctcg tatgatgaat aatccgtgcc tgaatgcgca
     1381 atatatcatc tatctgaaca gcctgcaaaa agtagatcag catctgctcg ataatgagat
     1441 tgcgaccact attaacaact aaatcttggg tcatgtgggt cagaatttct gccaatacac
     1501 cattagccaa aactccattt ttttctagca taaagggttc cactgtaatg actacttcat
     1561 catggtgata agagagcttt tgtccaatct gctcagaaaa agttggtaga gccgaaactt
     1621 gggaacggct catcttctcc atgacatctc gtcgcgtcac aacgccaagc aaagtttgat
     1681 tgcttcgaac aactggtacc atttcaaagt cttctgcgat catccgttga ctcacattgg
     1741 caatatttgt cgataatcca accaaaaata gactacgaga cataacctta tcaattgtcg
     1801 tgcttggtga tttatcacca gcgtctctca tggttacaac gccaacaacg acctgatgtt
     1861 gattgataac agggaaacgg ctgctacgat tcttacgaac caagtccaaa taatctttaa
     1921 ctgtatctgt ctctctcaga aaaccatact catgactagg gcgataaagt ttctcaactg
     1981 tcagaatatc agtcttgatt tggacatttg acaaggcttt attgatcatg gtcgcgacgg
     2041 taaaggtatc atgcttactt cttagaacag ggatcccttt ttgattggcc agtttaagca
     2101 catcatcatg aacctgaaat ccccctgtaa ccagaactgc attttcattt tccaaggcta
     2161 gcgactgaat acgggttcgg tctccgacaa tcaagagccc cccatcatga aggtaagaca
     2221 agatattttg ttcagtcatg gcaccaattg aaaacttact aaattctctc tctaaacctt
     2281 cttgcccagc cagaacctca gaagaagtca cttctgcaat ttcagcaaac gttaatctct
     2341 ctatagcaac tttctgggat ttaacacgaa ttgttccact tctaggacgg gtctccacaa
     2401 ttccacggtt ttcagcttct ttaatagccc gataggctgt tccatcacta actcctagat
     2461 gattcgaaat gctacgaaca ctgacccttt tacctactgg taattcctcc aaatagctta
     2521 gaatttcctg atgcttactc attgaactct ccttttacat accgaaattc aagataatcc
     2581 cgcatttttc ttgtgtaacg atcacttccc ttaaactgac ggaacaaact aaatccagac
     2641 ttaagagcaa ctctttggct agcttcattt tcaaggtggg taatgataga taattgtttt
     2701 aagccaaatt cctcaaaaga aagctgacaa atttttctaa caacctctgt cataaatcct
     2761 tgcgaccaag catcttttct caaaaaatag ccaagctcag cttctttttt gatttcatct
     2821 aacttctcaa atttaataga accaatcatt tgttgatttt tctggtcaca aattgcccac
     2881 actcccaaag gggacttcat aaagtaattg gccagtgcat attgactttc ttccagactt
     2941 gcctgcgttg ggaaaataaa ttgaagattt tctggatttg aagctatctc gcggaagtcc
     3001 tgactatcac taaaaaagaa aggacgcaaa tacaagcgat ccgtttcaaa aaaagaaaac
     3061 attgctaatt tggtccaaat attcataaac acctctacgg tttaatcctc aacaagtcta
     3121 atatccgctc ctaaattacg taatttttcg ataatatcag aataaccacg taagataaac
     3181 tcgatattgg taatttcagt tttaccttca gccataagcc cagcaatgac tagtgcagcc
     3241 ccagctctta agtcggtcgc tttaacactg gtcccacgta aataacgtcc acccgtgtac
     3301 aaaatatgac catttgttgt cgaaatatcc gcatccatct ttgctagttc aaaaacatga
     3361 tttacacgtt tttcgtaaat cgtatcgaca attgtaccac gaccattcgc tcttagtaaa
     3421 agaggggtaa gcggttgttg caaatcagtt gcaaagcctg ggtaaggagc tgtcttaata
     3481 ttgattgctt tcaaattaga ctgttcctcg acaaaaatgc tgtcttcaga tacagtcatt
     3541 ctcactccca tttcttccaa cttagcaata aacccttcca ggtgttcgta aagaacatta
     3601 tttatacgaa ttcctttacc aactgcagca gctaaagata tatatgttcc agcttcaatg
     3661 cggtctggaa tcacctgatg acgtgtccca tgtaatcttt caacaccatc aataatgatg
     3721 atattagttc ctgccccacg gatatgggca cccatattat tcaagagagt agctacatca
     3781 ataatctcag gttcacgggc tgcattttca ataatagtac gaccatttgc tttaaccgca
     3841 gcaatcatcg tattaatcgt tgctcccaca ctaaccgtat ccatgtaaat acttacacca
     3901 tgaagtcctg tatctttagc agataacttc atgttatctc cctcgtagct agcagtggca
     3961 cccatagctt caaacgcctt aaggtgtaag tcaatcggac gaggaccaag atcacatcct
     4021 cccggtagac caactgtcgc ttcaccaaaa cggcctaaga ggctcccata aaaatagtaa
     4081 gatgcacgaa gactgttaat tttaccataa ggcattggaa tattttgaac acctcttgga
     4141 tcaatctcca agacatcgtc ataacgctta acagtagctc ccatcaattc catgatttcg
     4201 acaagactgg ctacatccga aatatctgga acacaatcca aagtcaccac atcatcagcc
     4261 aatataatag ctggaattaa ggccacaaca ctatttttag caccactaat agtaatttca
     4321 ccttgcagtg gtaatccacc attgataaca atttttctca ttctaagttt tcaatactct
     4381 ttcaagattt ctaataaggt cttcaaaata aagtatatca taaatttatc cttttttcca
     4441 tccttttcaa ttttattgga taaatcagag ttgacgagtt agtaactgaa ttactaatac
     4501 tcaataaaaa tcaaagatca aactaggaaa ctagccgcag gttgctcaaa acactgtttt
     4561 gagattgtag atggaactga cgtagtcagt atcctacaca tacggcaagg cgatattgac
     4621 gtgatttgaa gagattttcg aagagtataa tctttctcga atcgctattg cccctttttt
     4681 atcccctaaa actgagtagg agctaagact agatctctta tctaagtatc ggaatacggc
     4741 tgttcaacta aattttagca agaacttctc ccccttctct cagttcacag aagcgtttta
     4801 tacataccgt cctatcagac aatctatttt aaagataacc gtgactcagg atcacttcta
     4861 tctgtcgttt tctctttata gtgatagacc tcacgggata agtcgtacat ctttcctcgt
     4921 gtatacaaga tataagggcg ttaaaagctt acagtgaaaa tagaaaatct tagtacgaat
     4981 tcaattactc tcgtaattta cgcatatagg ttacgaatac ctttttggac tttagagttt
     5041 gaggccctct tatccgctat atacgcctta ttatcacgtt cctgttcgta gagccacgag
     5101 ttcgctatcc cttcttctga caattcttat ttccagcgtc agacttaaaa cggtctatcc
     5161 ccagaccatt ttaatccgct acctcacgat agtcaggctt gggaatcgct atttgactcg
     5221 ccgagaactt tgacatcaga tatactataa caaattgaaa taagaatcaa acaatttaat
     5281 tttgaaattc aaatcaattt ataacaatat agttgattga aactagaata gtacacctct
     5341 gcttctaaaa cattgttaga aatcgatttt actgtcctga tcgatttgtc ctgttctcat
     5401 ttcattttac tatattttag aagatatgct gtgctattcc agattcagtt cgctatacat
     5461 gcccgtcgta ccacaaaatc ccgtgtctga tgaggcacgg gattttttag cttctttact
     5521 gagatggatt ttccttttta gttcgtgcca atctcaaggc acgatttgga ttgagacgat
     5581 taaatagttc ttccaatttc ttttcattcc aaacgtctgc ggcggaaaca aaattaccat
     5641 ccgcatctcg gaaagatatc ggtttatctc ccataccagt ctcctagtct acaaattcaa
     5701 actcaaattt accaatgcgg accaaatccc catctttagc tccacgcgca cgaagggctt
     5761 catcaacccc cataccacga agctgacggg caaatttcat gacagattca tcacgatcaa
     5821 agttggtcat attaaagagt ttcatgagtt tttcaccaga aagtacccat gtcgcatcgt
     5881 catcacgact aatttcaaag gctttttctt cttcgtcaaa tccatagtaa gcttcttctt
     5941 ccatatcgga ctcgtcgtag agcaaaaatt ctggtgtctt gtctaacaat tcagctgtag
     6001 catctaaaag tgttgccaga ccttgcttgg tcaatccaga aattgggaag atagctggta
     6061 actcttcaaa ttcatcataa ttttcagcca attttttctt aaattcttca agattttcct
     6121 gactctcagg catgtccatc ttattagcta caataatctg tggacgctcc atgaggcgaa
     6181 gattgtaaga ctccagctct ttattgatag ctaggtaatc ctcatatgga tcacggcctt
     6241 cgctagctga catatcaatg atgtgaagga taacacgtgt acgctcgata tgacggagga
     6301 actgagttcc caaaccaaca ccttgactag ccccttcaat caaacctggc aagtcggcta
     6361 ctgcaaagga ttcacctgat tgggtgcgaa ccatacctaa atttggtaca atagtggtaa
     6421 agtggtaggc accaatttta ggcttagctg aggtaataac acttaaaagt gttgacttcc
     6481 ctacagatgg gaatcctact aaaccgacat ctgccaagat ttttagttcc aattgtaact
     6541 cacgttcctg acctggttct ccattttcag agatttccgg tgcaggattt tttggtgtcg
     6601 cgaaacgaat atttccacgt ccaccacgac caccgtgggc aacgataaat tcttgcccat
     6661 gttcaatcaa atctgttaaa accttgccag tctccgcatc acgaacagtc gtaccttgtg
     6721 gtactcgaac tctaaggtcc tcagcaccac gaccatgcat ccctttggtc atcccttttt
     6781 caccagaatc agccttgaaa tgacgattgt agcggaaatc catcaaggta cgtagtcctt
     6841 cgtctacaac gaagaccaca ttgcctccac gaccaccatc accaccccaa gggcctccat
     6901 tagggacata tttttcacga cgaaaggcaa ccataccatc gccaccatta ccagccttga
     6961 ccttaatctt agctgtatct aaaaacatac tcattatttc ttctcacttt aaaaaagggc
     7021 tgggaaatcc cagtcactaa attttcttga atctatttta tagactactg agggcaccaa
     7081 ttgcagttgc aaaaattccc aataaacttg ctactagcat gataatcacg ataaacaagg
     7141 ttattttctc aaacatagtt tttttacgat ttccattatc tccaaatgcc atttttctct
     7201 ccttcgttac attctatttt ctattatctt agcatgaatt gagctagttt tcaatagtca
     7261 gttgctactg gtgcgataat ccataaaata atgtaagcta caattccagc tccgtaacag
     7321 caagtaagaa caccccaaat gacttgaacg atagtcggat ccatatccag ataatgggcc
     7381 accccagcac aaacacccgc aatcttttta tcacgaccgc ttctcattaa ttgttttttt
     7441 catagctgtt cctctttcta ttcttcatgg tctttccaat agtctctcat actgatcaac
     7501 tgtgtttttg aagccttcaa catgcgtcta gatcctttta caggtacagc aaccacctgt
     7561 tgctgaagat acaaaactgt cttaaagata cgctgactga ccgtatcatc tttagccaaa
     7621 tctttctgga agttatttga aataatggca tccagataaa actcatgcac tcgtttccca
     7681 aagttctcag ctgaaatctc atacaatttc tctgataagg tatgctcgtt cacgtctggt
     7741 gttgcaatca gggcttccaa aatagcacca gccaaatcat gttctccata gtacaaggtt
     7801 ccaaacattt tatcactgat gaggttgttc aaataaggat ttccgtgagc aatgacaggt
     7861 gttccactgg ctaagctttc caagtaggtc aaaccttgcg tttcgcttgt cgatgccgaa
     7921 atgaagaaat ccgccgcttt atagtaaaga gccgtctcac taggagcaat catccctgta
     7981 aagatgactg agtcttgaat ctctaggttc tgagcttgct ctttgaggtc attcagataa
     8041 gggccatccc cagctactac cagtttaacc ttgtcttcct ctttcagaac atcagaaaag
     8101 gctgctaaaa ctgcttgaat atttttttca taggagattc tcgaaagact aagcaacgtc
     8161 ttttcaccat cttgaatccc tagtttacta cgcagttctt tcaaattttc ctgcttgatt
     8221 tccggacgct caaacttggc taattcaatc ccagtaggaa tgacccgttt ttcaaccttg
     8281 accttataat cagatagcaa gtcacggaca atctcactag gacaaataac cccatccaca
     8341 tcatgcagga aacctctaac cagatacttg accatactcg gccggatcaa catcccctta
     8401 gcaatataat ggacatagtc ttcatactgg gtgtgatagg tatggatgac tggaattttc
     8461 aattcacgcg caatccaaat ccccaacagg ccaagagaaa attctgtctg agtatggata
     8521 atatctagct gatactgttt agcaatttca agtgccttgc taaaacctcg gtaggcaaag
     8581 cgacgatcct taaaagcaaa gaaaggaaca cttggaatgc ggataatttg ccaatcttcg
     8641 tagcgattga catccttatc tgtcgtcgta aagataaaaa cagcatgtcc ctgcttttca
     8701 agttctgttt tcaaggttcg aatactggtc gcaacaccag aaacctgagg aaaataggta
     8761 tctgtaaata aaccaattcg catagattac ctcacttttt actttctccc taaagcggct
     8821 tgtttctcat aaaagtccaa ccagatttgt aacagatgct cttcagaata ctctctggaa
     8881 atattcttag ccttttcttt gagatctttt aaggcagcag gatttgcttg atattccaaa
     8941 atagcctctt tcatctcttc tctacccgct gtcgcccgat aatttccctc caaaatcacc
     9001 ttatagagat ctaaatcacg caacataata ggagcctcac aactcgcagc ttctaaaata
     9061 gtcataggaa agagctcatt gtaactaggc aacaagaaaa gatccgctag agcatacaat
     9121 tcgcgcatcc gctctggcga tacaatgcct ggaaaaatca aatttttagg gggattttcc
     9181 ataattttct tatagtgttc ataaccatct gtcataccac caaaagagaa gccaccagcc
     9241 cagataaagg taatctgagg caattcctca gccagacgga taaagtcatc aatcccttta
     9301 cgtttctgaa cttgcccagc acctactacg ataaactgat tgtcactaag accaagatct
     9361 gtgcgcagtc taactacctc ttcttgtggt agaggatgcc atttttcctt gttgacaaag
     9421 ttaggaatat aggtcacttt ttcacgtgga ataccagctg ctaccaaatc ctcaataaac
     9481 ataggattga ccacaaccaa gtgctccatc cggttgtaaa aagaaaatac atagcgtttc
     9541 acaatttcct ttaagaaaaa tggaattttc aaacttccct caagtgtagc tggcaagaaa
     9601 tgcacatagc caatctttct ccctgagcgt ttcttttgga aggttgataa ataataggga
     9661 aaatcaatcg tatgaaagtg agtcacatct gcctcgatcg gaagattttc tgtaacaatc
     9721 aattggtcct tggcagcacg gtgaagaaga cgaactaatt cacggtaagc acctgaaact
     9781 ccctgtcctg ctactttctc acttgaactc aacatattga tgcgtaattt ctttttctcc
     9841 ataactacta ttatatcatt ttctttgaat aaaatcagca aaagaaagga gagactagag
     9901 gaaaagaggg gaaatttcct cgcttttcca acagtctctc acatgctttt atatgtttac
     9961 ttaatgccta gggcaatgcg ggcatagcga ctcatttttt caactgtcca ggctggatac
    10021 cagactaatt taacctcagt atccgttact tctggaacct ctatcatagc atcataaatc
    10081 tggtctgtca aaaggtctgc taagggacaa cccatagttg tcaaagtcat gtcaatctct
    10141 gtttgccctg tgtcaccgtc aaaacgaatc tcatagatca aaccaagatt gacaatatcg
    10201 attcccaact cagggtcgat gacttcttcc aaggctgtta aaatccgtgt tttgatgttt
    10261 tcaatttgct cttctgtata agccatattt tcctcactct tagtcttcaa taaaatcacg
    10321 aagcggtttg ctgcggcttg gttggcgtag ttttctcaaa gcctttgctt caatctgacg
    10381 gatacgctca cgagttacgt taaagacttt ccccacatct tcaagtgtgc gcatttttcc
    10441 atcatctagt ccaaaacgta gacgcagaac attttcttca cggtctgtaa gagtatctaa
    10501 gatttcatcc aattgctcac gcaagacgat acgagtcgta taatccactg gattttcaat
    10561 cacttcatct tcgataaagt ctccaaggtg gctatcgtcc tcttcaccga taggagtttc
    10621 aagagatact ggttcttggg caatcttcaa gatttcacga accttatcag gtgtcatatc
    10681 cattcgttca gcaatctgtt ctggtgtcgg atcttgcccc aattcttgaa ggagattccg
    10741 ctgttcacga accaatttat tgatagtttc aaccatgtga actgggatac ggatggtacg
    10801 agcttggtcc gcaatagcac gagtgatagc ctgacgaatc caccaagttg cataagttga
    10861 aaacttgaac cctttagaat agtcaaactt gtcaaccgcc ttcatcaagc ccatatttcc
    10921 ttcttgaatc aagtcaagga actgcatgcc acgaccgaca tagcgtttgg caatggaaac
    10981 aaccaaacga agattggctt ccgcaagacg ttgtttggct tcgatatcgc cagcttcaac
    11041 agccagtgcc aactctttct cctcttcatt ggtcaagaga ggaacgaccc ctatttcttt
    11101 caagtacata cggacagggt cattgacctt agcagaagtt gatccaatca agtcctcatc
    11161 gctgagttct ggttcttctt cattgctaag aacacgcgca cttggatttc cttcgttatc
    11221 tgtgatagaa atccctgcat cctgaatccg ttgcaagaga tcttcaatcc catcagcgtc
    11281 caaggtaaaa ggaataacca gacttgcatt gatttcatca tctgttgctg tccctttttg
    11341 cttatgatta cggataaatt ctgctacctg tacgtcaaat gttgttactt ctttttgttt
    11401 tgttgccatt attactccat tcttctcttt tgggaaatta aacgttccaa ttcttctagg
    11461 gctgtatctg tatctcctac atggctagct tcctgcacct tctttttgat tctcatattg
    11521 tcctgattca agagagcctt gtttcgagtc atctctactt cactaagttc ctgcggcgat
    11581 atctcagcag gcaaatcctg agctaaaact tggtaccaag ctctttcaac ttcctctgtc
    11641 tgctctgcta aaacttctgg aggaagattt ccatactggc caagcaagtc atataagacc
    11701 tgaaattcag gtgtagcaaa tgcaaagtct tctcgcaaac ggtaatcgtt caaaacaaga
    11761 ggggattcca tcatccgata gagtagatgg gcttctgccc tcataatagc cgataactgc
    11821 ttggtgacag gcatggtgat tggcgtcggt ctggaaattc tttccatgcg attctgcctt
    11881 tgcacctgac gactctcatt aacaatctgc tcaatctggg tataatcaaa ggacgccaga
    11941 ctgtcagcta aaatatgaat atagctgttt tgagcagcga tggacttttc ttgaacaatc
    12001 aagggagcta ttttttcaag aaactcaatc tgagcctgca gattttcact gttttcaggt
    12061 ttgtactgat gaatgtagaa ctcaatcgga ctaatacgag ttttcgttaa tagataggcc
    12121 aagtcttctg gaccattttt ttgtagatac tcatcaggat ccaagttatc aggcatgcta
    12181 acgatttgca caggcatatc accaatttca tccaatgctt tcaatgtcgc ggcttgccca
    12241 gccttatctc catcgtaaac aagaaccaat ttcttggtta accttttcag atgctcaaca
    12301 tgctctcgac tcaaggccgt tcccatcgac gccacagcat tttcgattcc agcccgatag
    12361 gctgcaataa catccatgaa tccttccatc aggtaaatct cactagcttt tccagaagat
    12421 ctttttgccc tatccatatg atataattcg taacttttgt taaaaattgc agtcgatcgg
    12481 ctgtttttat acttagaagt ttgtgaatcc gttttttgcc agatacgacc tgagaaggca
    12541 atgacctttc cttggtcatt tgtcagggga aacataatgc gattgtgaaa ggtgtctaca
    12601 aattgattgg catccgagag ataaaacagg cctgaatcca gtaaatcctc ttcacgatac
    12661 tgatcagaca aacgttgata gagatagttt cgttctggag gtgctaaacc aatccaaaaa
    12721 tgtttaagca cttcatctgt caaaccccgc tgataaaggt aatttctggc ctcttcgccc
    12781 atagtcgttg tcatgagaat agcatggtaa aatttggctg catcttcgtg catatcataa
    12841 agatcttggt gaggtgaggc tgacttttgc tcactataaa gcggtttttc aacctcaatt
    12901 ccaacacgct gacctaagat ttggactgcc tctataaagg gaaccccttg gtactcctct
    12961 atgaacttaa agacatcacc tgagcgacca caaccgaaac agtgataaaa ctgcttatcc
    13021 tctacaacgt tgaaagaagg tgttttttca ccatgaaaag gacagagccc tagatagttc
    13081 cgtcctgcct tttgtaaaga aatcacatct cctatgactt ccacaatgtt ggcattgttt
    13141 ttgatttctt caatgacttg tttgtcaacc atacacaata cctccatgtt atcatagttt
    13201 actttatata gtatacttta tttcagaaaa aaagtaaacc atttcactca ttttccttac
    13261 tttattcaaa gagttgataa taatcagaga ttttcatttt tgctttttct tcttggttta
    13321 aatcttggat aatccgtcct tctttcatga caatcaagcg attgccgtat ttgagagcat
    13381 cttccatatg atgagtaatc ataagggctg ttagctgatc tttcttaaca aattcatctg
    13441 tcaattccat caaagcaaca ctagtctttg gatccagggc agcagtatgc tcgtctaaca
    13501 agagtaattc aggtcgcttc aaggttgcca tcaagagact caaagcctgt ctttgtccac
    13561 ctgataagaa ctcaatcggt gtattcaagt gtttctcaag accatttcct actttttcaa
    13621 tggttgcctg aaattcatcc ttatagctag tcaagcgtct tggtaacaat ccacgctttt
    13681 caccacgaaa cttggcgatt aaaagatttt cagcgaccgt catacgggga gctgtcccca
    13741 tctttggatc ttggaagaca cgagacaggt acttggcacg cttctcgggt gaaaacttag
    13801 tgagatcttc acctaaaata cggatagttc cactagttag tgataaggtc cctgctatag
    13861 tgttaaagag ggttgatttt ccagcaccat ttccgcccaa aatcgtgata aagtcccgtt
    13921 caaaaatttc taaggaaaca tcatttaaaa taatcttttc ttcatcaaag ccatttttaa
    13981 cgattttggt tgcatttttt aattctacaa ttgctgtcat ttgcttaact tggctccttt
    14041 caagattgtt tgcttaaatg ttggaatcat gaggcagact gctaaaatca aggcactgta
    14101 taaacgaagg taacttgtat taaagccaag tgcgataact gcccacacta aaaattgata
    14161 agcgatagaa cctacaacga tagtaaccaa acgctctgcc aagctcaaac tcttgaaaat
    14221 aacttctcca ataatcaaac ttgcaagccc cacaacgata accccgatcc ctcgagacac
    14281 atcggcataa ccttcttgct gagcaatgag ggcacctgca agggcaatca caccatttga
    14341 taagaccaag cccatgagct ccatgcgtcc agtatgaatc ccgaaacttc tagccatatc
    14401 aggattatcc cctgtagcaa tataggcttg tccgagttta gtgtccaaga aaaagagcat
    14461 gagagcaata acaatgctca caaagatgag acctgtcaag agttgattca aatccgaatc
    14521 aaaaggcaaa acatcctgaa tttgcttggt tccaagcagg cctaaattcg cacgtcccat
    14581 aatcaagagc atgattgagt gacaagaagt catcaccaaa atccctgaga gcaaggttgg
    14641 gatcttccct tttgtataaa gaaggcctgc tgccattcca gccaaacaac ctgctcctac
    14701 agcaacaagt gtcgctaaaa atgggttcac gcctttggtt atcaaagtga cagcaacagc
    14761 tcccccaaga gggaaggaac cttctgtcgt catatctgga aagtttaaaa tcctaaatgt
    14821 cataaagatt cccagaccta gaatagccca gacaaatcct tgagaaataa tggaaacaat
    14881 catattttat ttaatccttt ctatattcat ctttttaaaa aatgggaaga gtctcctcct
    14941 ccctacctta tttattcgat gacttgtcct gcttctttga gaacagactc aggaatagta
    15001 atacctagtt cttgtgctat ttttttattg atgactgact taccaattga aaagacattg
    15061 actggggtat cggctggttt tgcacctttc aagacttgca caatcatttt acctgttgcc
    15121 acaccaaggt catgttggtc aattacaact gatgccaaac cacctacttc taccatagct
    15181 gtcgcactgg gataaattgg tttcttagaa ctttgattgc tagagacaac cgttggaaat
    15241 cctgatgcaa tggtgttatc aattggaacc caaatagcat ctaccttgct agtcataaca
    15301 gtgacagttg aggcaatttc atttgttgaa ggaactgcaa atgtttccac tgtcagacct
    15361 gctttttcag cataagcctt aaattcttcg acctgtgttt ttgaattgtc ttcgctactt
    15421 gagtaaagag ctccgattgt tttcacattc ggtgtcagag ccttgatgag ttcaacttgt
    15481 tgttgagctg gattgtggtc agatacccct gtaacgttgc cacctggttt tttcaaatct
    15541 ttaaccaagt tagcaccaat tgggtctgta atagcggcca tgataaccgg taggtctttt
    15601 gttgcactag ccaacccttg ggctgctggt gttgcgatac caaccacaag gtcatttcca
    15661 tttgcaacca attgtttact cattgtcgca accttacttt ggtcaccttc tgagttcata
    15721 aaatcaattt taacttgatc atctttatat ccttcttctg caagtccatc ttggatccct
    15781 ttataaatca aatcaaggga tggatggctc acaaattgaa gcacaccaat cttggttatt
    15841 ttcttctcat ccttattatt ctgaacttct gatttattca ttgaagaata aatcaagttt
    15901 cctgctacta agactgctaa tgcagcaata attccaatta aacgtttatt tttcattctg
    15961 tttctccttt ttatttcctt taacatattt cacttatcta aacaagcgac gccatcgttt
    16021 tctttccata ctaacctcca tcaaaaaaat cctcacacaa aaaacttgtg tgaggacgtc
    16081 gatgcgcggt accacctcaa ttatagggaa tttccctatc gctcagtctc gcaataacga
    16141 gatgcactgt aaggtgtgct taccgaattt ttataatttc aaattctaaa tagcattcag
    16201 cccaattttc atcatcgcca cttatctgtt ttcagctacc acagactctc taaaaagttt
    16261 gtatgattac ttttctgaat ggttaaatta tatcattttt aaactacttg tcaatagtct
    16321 attagaattt ttttgatatt cacttttagc attcactctt gaaaattatc aacctgaatt
    16381 acgcaatcct gtcgcaattc cgttgatggt gatatgaatc aatcgttctt gatcactgga
    16441 caattctcca cgacgttggc gtttaatcaa ctctaactga atatagttga gaatattaaa
    16501 gtaaggcata cggtaatcca gactagcttt tagatatgga ttgtcagcta agagttcgtc
    16561 atgtccttca atagccaaga taacgttctt agtaacttgc cattcattta aaatagtctc
    16621 atagatggcc ttaacttgct cgtcttcaca aagtttagca tattcaaaag caatattcat
    16681 atttgatttt gacaaaacca tatcaacatt tgaaagaagc gattggaaga aaggccaatt
    16741 ttggtacata tctcgtaaga tagcaatatt ctctggattt ttattgataa attccttgaa
    16801 gcttgaacca accccgtacc atccagggaa cataacacga ctctgtgacc atgagaatac
    16861 ccaagggatg gcacgcaaac caccgatttc agtaatagtc ttacgagcgg ctggacgaga
    16921 accaatatta aaacttgaaa tagccttgat tggacttgac tcgaagaaat aatcatagaa
    16981 atgctcatta ccaaagacca aatcacggta gatatcgtaa ctacggtcca ctacttgatc
    17041 cataatggct tcataacgat ttggggtatt ggtatcgctc ttcttctgag taatcatacg
    17101 gttaatagct gccgatacta gcatttcaag gttatagtaa gcggcgtctt tgttaccgta
    17161 tttattccca attacttcac cctgctccgt caagcggata cgatccttga tagacttgag
    17221 cggttgagat gtaatggctt cataggttgg cccaccacca cgaccgacag taccaccacg
    17281 accatggaag aaggtaacct taacgccaaa ttcatctcca atagcagtca attgttgttg
    17341 agccttgtag agggtccaac atgatgacag gtaaccgcca tctttattac tgtcagagta
    17401 gccaagcatg atttcttggt agttatttcg tgagtcaatc cattttttgg caaggctaag
    17461 agaaagatat tttctcattg tttcctctga atgatccaag tcttcaattg tttcaaaaag
    17521 gggaacaatc tgaacacgcg ccctttccgt atccaccagt cctacttctt ttaacagaat
    17581 agctaattct agcatatcag aaaggctggt tgcatgtgaa atgatggtct gacggatgac
    17641 atcatctccc aacttatctt tcaaaacacg agccgtctta aaaatagcta attcttttgc
    17701 taataattct gatttttctg cgtgagtcgc agaaagaatt cggggatctt cttctaattc
    17761 tttcaagaga aggtcacact tttcttcttc gctcaactcg ctataacgag aatgaattcc
    17821 tgctgatttc aagagttctg ccacacaggc ttcatagacg ctagagtctt gtcgcatatc
    17881 aattgacgct aagtaaaaac caaatatctc tactgcctgc aataattcca caaaatcacc
    17941 tgaaatcaag gactcaccct tattttctag tagagaatct cgaatggcaa tcaaatcctt
    18001 gtagaaatca ttggcggttt cataacgagt cccaacttct tcatcctcaa tcagataggt
    18061 tttagttgcc tgaatttttg attgaatatc aaacaaggca cgacggtaaa gctctttttc
    18121 gcggtaaatc gagttatcct tggattgacg agccatttct ctgacttgct tgctgacgtt
    18181 gacaatgcta gttgaaagag aaaattcacg ataaagttgg taaatctttt tatcatagta
    18241 gttcatgatg acttcacact gagtgagtgc agactgcttc aaggtctttg ctgtaacaaa
    18301 tggatttcca tcacggtcac cacctatcca catacccatg gtgattggtt tagcctgttt
    18361 taaattcaga ccatgcgctt gcgctaagcg cttatactcc gtcgtcaaat gaggtacagc
    18421 tttcaaaaag gagctgttat aatattccat agcattcgtg atttcgttag tcacttttaa
    18481 ttttttctca cgaatcatgt ctgtctgcat gataatttcg atgtaacgac gcaaatcatt
    18541 gtaccattta tctttattaa tcaaccccaa cttaacatca cggtatttac gcaaaagact
    18601 atgaatatga tttgttaaat ccaacatact tttgcgttgc acttgtgttg gatgggctgt
    18661 caaaacaggg acaacattca agtgttctag gatctcaacg gcattttcct tttctgctac
    18721 caatttaatc gttgtagata atttacctaa atagtcctga tcaatattat tttgatgatt
    18781 gatttcataa gctaaatcca catcctctga aatattaatc aaaagaggca agatagagaa
    18841 atagcgtgaa atatagacca tttcatcatt tgataagcta gtcactagac ggtttagacc
    18901 ttgataatct tcctgcgttg ataattcttt caactgtatt attttttcaa aggtctctgg
    18961 ggcaagcata tttttagtaa tatcttccag taattctgtt agaatcaaga cttcttcttg
    19021 cacaacactt ttattactat aattttctaa tttttgaaga gacataaact atcctttctt
    19081 tatcctactt caacagaagg ttcattggtt gattttccaa ttctcggtac aatttagcgc
    19141 gtttttcact ggcatcaata tttaagacaa aggctactgc cactgataag actagaagac
    19201 tatttccacc ctgggataag aaggggaagg ttactcctgt agatggaatc aagcccgaaa
    19261 tccctccgat attgacaaat acctgaacca acatcatccc tccgacaccg agtgcaacca
    19321 tggcattgaa aggattctcc gctcggatac cgaccaagat aatccgcaaa atcatgaaaa
    19381 ataagagagc taaaataaga ctggcaccaa caaagccaaa ttcttcaatc acgatagaaa
    19441 agacaaagtc tgtatgagct tctggcaaat aacctcgttt ttcaatcgag tttccaagac
    19501 ctagaccaaa ccaaccgcca ttgaccatgg caaaataaga attagctaac tggtgacctg
    19561 catcagcacg atcggcaaaa ggattaaaaa aggcactaaa gcgcttggct acatagccaa
    19621 atactggaat ttttgaaaag gtctcaacac cgattaggct gatagtggtc aagacaaaga
    19681 cagaagcggc agatacgagc gccagaatgg ttgaaaacca gcgataagcg attccactaa
    19741 ctgtatacat aatcaaggaa accaagacta aaatagtcgc atttcctaaa tcagggaaaa
    19801 ttcccaaact tccaatcaga actaggagaa cgaatcgcca atcattaaaa gcacggggaa
    19861 gccattgatt ttgagtcaaa acttgaaaat cataagtagc tatttcttct tgctgtttgg
    19921 agaatcggtg agctaaatac caaataataa tgatttttaa gtactcagct ggctgaatag
    19981 ttattcctgc aaccgaaatc caaccgtatg ccccgtttac ggaaatacca ataaaacgag
    20041 ccaagaacaa taaaagcatt tctattaata taactaaaat gattagtcgc tcatttctca
    20101 aaaaatctag tctcaattta taaattaagg caatcagtat caaactaaca atccaaaaga
    20161 ttccttggtt tcgaaccaac tgcaaggcgc tcttgccttc ttcaattaaa atagcactgg
    20221 tggtcgaata gaccacaatc aagcccaaaa tagataaaag caagtaggga atcaagatgg
    20281 aataatttaa taagtgcctc ttactaatct tcatagtatc accactctac taggatacag
    20341 acaaatctgt tccaaattcc gttttatttt ctagttttga ttgctattat accatttttt
    20401 cagaaagaaa aaaactctta ccttacaatc cttcgaattt tactgttttt acagaattaa
    20461 ggcagaattt gaaatcgtaa aaccattttg aataagagtt gcttcaatcc attgactccg
    20521 actaattatg ttgctttcgt gaatgccaaa atcagccgca atttgttcat aagtgtgcta
    20581 ttctcgcatg tattgaatag ttaccatgag gagatcgtct aggcttaatt tggtttttcg
    20641 tccacctttt gcgcgtttac gttgcgttga taagctgttt ttaacacagc taacatctcg
    20701 tgcgctgaac acctacaagg ctcttgaaac ggctatcgct taattgttta cttgcttcat
    20761 catccatagt tttattgtat tgtatttttg tttcgcagga agtctattat tcctttcgtt
    20821 ccaaggtttt tacgctttta gcaacaagct tacacactcc acgtgatgcg tctgtggaac
    20881 tcaaaaggtt cggggaacct tttgaggatt aattgcgttt ctctaacaaa ctcacacatt
    20941 taacgtggca tgactgatga agtcatcata agaatttcac ttgctgctct tttacgatgg
    21001 cagcctgaac ggtcagaagt atcattgtat atcatttgta tcatggcata taaagtatcg
    21061 ctctatttta ttgatggttt taatatctct cggaaaagtt attcttgatt aattatagaa
    21121 acatttggat tgccagtttt agaagcacca attatcttaa cttttaaagc ttcgtacaaa
    21181 ctaattctat tttctagaat ataagctaat tcttgtccat ccataaataa aattttagca
    21241 tctttattag aaaaatcttg tattacttca tctctaaaac catttattga aagaaacagt
    21301 ccccgagtcg aagttagttt tgtatcaact ttttgtttta aagaagctat tttcggagaa
    21361 tttactggat tttttttccc atttcatttc aactaaataa tcaaaacctt caaacctaaa
    21421 atagccatct aactgttgag tatttgttct atttctatac gaatcatggt aatcaatatc
    21481 attaattctg aataaattag caacaatttt ttctaaacga tatcctcttt cttgaggatt
    21541 atcacttgaa aatagcgaat aatactccgt ctttagttct tcaatttttt gaaggagttg
    21601 ttgcctgagt tgtattttca tttcctgtct ggaacgatga taagaattat taagtgtttc
    21661 gttaacctta ttctgttgag tatcacctat cagtcgcttt aattttctta acgcatctaa
    21721 tcctctatct ctatcttgaa cttcatcagg aatatttttc atcttataaa attcagttgc
    21781 tattcgtcta attatcaatc ttccattttc tgttttatta agttcattta taacattttt
    21841 cgcccaaaca aacttcggtt ccgatttcca ttttaatatt aaatcatttg gaactcccga
    21901 agtttgcata aatgaaacga cagtatcttt atagtgaaaa cataatccaa aacattgaat
    21961 aatttgttgt tggatttcaa aagatatttt agtcattttt tctccttttt atcaacaata
    22021 ttacatttca ttaattatct gtgtataata acttggaaaa tcactcaatt tatcttctag
    22081 tctagctgat ttctgtttga tttcatttct aatttgattc ttacttacag aattaatctc
    22141 ttgaccaata acttggacca caattctatc tgaaaaacct aattcataga tattgatttc
    22201 tttttccaga ggtagcccat atttcagcct ctttattaac atagtcaata cgtccaattc
    22261 ctctccaact agtttttcaa gaatattatt aatcgcattt aaaaccattg atgtttcata
    22321 ccctaatcca ttatcacaaa tagagattat gtcagacata tcaattggtt ttgacttacc
    22381 tcttttctca atactaattg atttttcagt acaactttcc aatatttgaa aataagaaat
    22441 ccccttaatc cagagttgag aaatataatt tagattttct atacttagtt ttctcatctc
    22501 tttgttattt gaaaaatcta ttattttctt ggttaaaaca cctaataact cttcttcctt
    22561 ctcacaagaa aggatagatg ttttattttc ctgaacccat tcttttaata actcagattg
    22621 atataatcca attgagtttt ttgcaattat ttcagtttct actgaactgg taattatttt
    22681 agattttatc aagataaata attcttttat tttttctttt tcctcttcat tacctaagaa
    22741 atatccaaat gtattttcag ctaaactatc agtctccaat tcagtagcat acatagaagc
    22801 aatataattt tcaattgcaa ttagggtatt atcaatctgg tctatcttag aattaaaatc
    22861 cttaaaataa agactgttct ttctttttaa ttttgataaa atattattta tttttgttct
    22921 gtagtctaca gaactgtcaa atctctcttt aatcaaattc caaaaatcaa attttatagg
    22981 agcgaatcga taatcagttg gaactactga tttaaactgt ataatactga gaatattact
    23041 ttgacaaccc tctgtattaa taggatttaa caatgcttta tagttttgtt ttttccactt
    23101 attttttggt gatttataaa tattgggctc tgttaaaatt attgttcctt ctgtatattt
    23161 tccagccctt cctgctctac ctatcaaatt ctgaaaatca cgaactttta ttgcatctcc
    23221 tgcttgatac acacttgaga taatcaagta tttaataggt aagtttatac cttgtgctaa
    23281 ggttgaagta catactacat tatttatttt actttttgaa aaagcatact ctatagcaat
    23341 gcgtatcccc ataggtatac ctgaatgatg tgaaaaaact cctagctgac tacatgtata
    23401 ttcaacacta tcatatccta aattttgacc aattaaattt cctatttttt caacttcaga
    23461 cctatctgag ttttttaaga aatcagttag atcataattt ctattattta agtctataaa
    23521 tcttcgtaaa ataacattga ccgtgtcttt tcttccacaa aaaattccta ctccaccatt
    23581 attaattagc ttagtcccat aataaatact tatatcattt gcgtttgtca gttctggaaa
    23641 aactttttgt ttgcgttctt ttccaagctg ctctaattca ctaacactaa cagtacgtgg
    23701 aacaaaaaat tcttcttcaa atgtaatagg atctatgaaa tataattgct cattactccc
    23761 gtttaaatca ctaaacgcaa ctcttttctc tgttgtttta atcgaattat tagaaacaat
    23821 tactccatct tcgttaaacc accgatttat agcttcacta tttggtatta cagcagatat
    23881 taaaatcttc tgtattcctt ttgggaaaat ttgtttaacc gttgacaaca gtaattcaaa
    23941 attggttcca cgacttggat catcaaaaag atgtgcttca tcaaatatac aaagtcctat
    24001 ttcatcaata aaactttgat gatttctcaa taaaaacaac aatttctctg gagtaagtat
    24061 aaaaactctt tttttaccat cattaaaaat tgagaaatcc tgtggaatct ccggtaaatc
    24121 aaaaacttca ctaacaatca cattattctc atcaacgaaa tgtgcattaa tatctcgata
    24181 tatttctcta cataatgctc taaaaggtgc aacaatcaat gcattatcaa ttctatttga
    24241 ataaaatgct gatcttaaag ttagattgat tgaggctgtt ttacccgaac ttgttggcat
    24301 ctgaacgatt ccagatttac ctgaaaaaat tccttgcttc cctaattcga tttgagatgg
    24361 ccaaagctcc tttatgcttc ctgttgattg tatataatcc tgccataaag aaaaatctaa
    24421 tcctgaaaat tcaggtaata atttcgttga tgaactattt atttttttac atacaactgc
    24481 taagagacaa tttacaataa ttacagaaaa atcgcttcca ttcctatata ctttatcttg
    24541 taaatctcta taaatatcta tagaaaactc agtttttgat aaaatataat ttctatatga
    24601 ttcaactaga gtatttaact cactagagta tttaccttct attggcgtat gattcaaaaa
    24661 gagttcatcc gttacaacgt caataaatac ttttataaga gtcatacagt cttctaataa
    24721 ctggatatca tccgatatat agttaatcat aactctcgaa ctaccattat aatcgcatag
    24781 ataataagct gtggtaccca atattgcaat atagtcttga tattcagctg aatttcctaa
    24841 tcctgacacc agcaatgcat caaaatattc agcagcattg tgtaattgat tttttaattg
    24901 taaattaaaa ctcttacgat tgatataaac ttcaaaatac ttcctagcag tatctgcaac
    24961 aattgctagt gccccaagaa acgatttttg agcatcctct gaaattggta aatgactttc
    25021 taaaggaata tcaaattcaa tcatctttgc ctttgaacgc actaattttg aaaaatataa
    25081 tgaccttctc ccaaattcta tcatacctca ctcgctttcg aatagagttc tctaataaat
    25141 ttcattaatt cattagaatg aatgaccaat agtcgtaatt tctgaaaatc tctgtgattt
    25201 tttgaaacta ctgtcttgat aacatcaata tcatatgatt gattggagta gactgcaaca
    25261 gctccataga ttacattaaa cggtttatcc gttatgttta aaaatctttc tactacattt
    25321 gcttgatcac tattagattt ctttaacctc aaatagctgg ctacaattga ggttgaaaat
    25381 cgttcaaaat ctttatcaga atgattaata gcttcttgaa gcttattttt cgctttagag
    25441 ctactagaat ctgatgcaga tgattttact tcaataacta caacctcatc attcgacaca
    25501 ttcgaagaat cttgcttata tcctagaaca tcacttcctt gagttgaagt atttttattg
    25561 actttactat cataacgagt cctaggaacc acatattctt caatatactg aagataatca
    25621 gatactaata tttctccaaa atctcctgac atcgttgaaa ggccaatacc actatccgag
    25681 ggtaatttaa aattttcaag atactcttta ggggagatat tcataaaacc tatcatttca
    25741 gcaagttcat catcagaaca ataatttctt ctgaattgtt ttgcccaatc ttcaaaaatt
    25801 tctgggtcat cttgaatatc taagtgaaga atctcaatct gcttaccttc atcagtaata
    25861 ataggatctt cttgagttag atactttata taactatgca tcttttccat tacttttact
    25921 catatccctc atccgttctt ctcccacctt caacatctct tcctctacct tgctccattt
    25981 tccgaagagg tattcttgta gcacttctgc tgctgaagtt gtattttctt ttgaatcata
    26041 tacacaactt ctatctcgtt ggtaaatttg aattctttca aaaatagcta gttcttccaa
    26101 ttgtcgtgta ttatcaacta gatgatttac aatgaaatca tgatgttctt ttggagttgc
    26161 gcgtgctgga tttggattga tagcatacag ttcttcgtat cggataaggg tgctcagata
    26221 ggacaattcg ggcttggttg caattaaggc taattgtacc tcatacccct tattttttaa
    26281 tagttgtgct gttttctttg gaacatcaat agttcgtaaa gttccctcta tcaaaagatt
    26341 gtatcccaaa tgactcaatt cggttactaa agactctacc attttccctg caaaatcttt
    26401 ggtgtattca acgctatctt tgccattttc ttgctgcagt tctaaatagt gtggatgctg
    26461 agaacgaaaa ctatcaccat ctatgataac aatatttcct tgaaattctt tctgtttaat
    26521 acgatgaatt gtagtcttac cggcaccact ttgacctcca agcaaaatcg ctatagattg
    26581 tttactggac ttttttcctc ttgtcagtga acgaagattc cttgctaaag catgtttgaa
    26641 ttcactatca gtataatctt ggatttccat taagctacca tccgcttttc agatatctct
    26701 aacatacgtt caattccatc caaatagccg ctatatctct ctatttcatc aaaattttct
    26761 actaaataga tatttgtctg aatcaagtca gatagatcat cactcattaa aatccaagga
    26821 ttagattcat catcaatgct aattccctga ctatcttgat aacgatagag tcgagataat
    26881 agattagcac ctctttcttt cacaatttca attttcaaag tcaattcata atcttcaaca
    26941 ggattgagca ttttatcttc tcctacaata tcgacataag atacattaaa cttctgacaa
    27001 atgatgtcaa ttaattccgt agagactgaa ctagttccat tttcataacg actcaagcta
    27061 tttcgagaaa ttcctataat tcgtgcaaat tcgtgttgtg ttaagtcatg tgttttacgt
    27121 aaggatttta tgttttttcc aatcatggca aactccttta tttttataaa tccattatag
    27181 cataaaaaag cataacgcac caaaaatggt gcgttattga ctgtttttct atcctaaact
    27241 ttacttctat aaaagtcacc taaagagcca taaatattta ttcttgtatt aattttttcg
    27301 atgcgcaaac gatatctaca aatacatcta taacgattca ccttttagga tttttattgt
    27361 caaaattgcc tttatctaca aagacaaaat gcttataaaa tagcttgaaa tcaaggatta
    27421 tcaccttttt cgttgtagca acactccaca tgtgattatt aggctattag caaagcgtat
    27481 ccaatacctc aataaagtgt tgtttttact gatattttaa ctatattgta tagtctacta
    27541 tttaaatctc aattaggata ttttatagaa tacccaaaat tcaacaataa ctaaaagtaa
    27601 gattccattg tatttccttg ttggtctttc atatcacgaa ttttattttt cagaatatta
    27661 aagttacaaa tttcatctct aatatcgtta tccgctctgt agccattaat catctcagtc
    27721 agagttttcc ctttactacc attctttata gtagtattta ctctttttat actgctttca
    27781 aaaggctcat atgttttata cttaattact tcgtctttaa aattaaataa aggtgtatcc
    27841 ggcttagcat tccataaaat aatcaaccac attataacat tataaagctg ctttgcagtt
    27901 tcattccact tttcaggttg taaatttcca ctccctgtat tgtcatattc ttgtctatta
    27961 tttacatgag aatcacctac aagcggatta aaaagaggta gccctttgtg attaattagt
    28021 tctaaaaaat cccttgccgc acccatgcaa cactgaataa cttccttctt gccatcaatt
    28081 ttactctcag cgataaatac ataatattca tcttcaatag ttgctcctgc atcactatgt
    28141 ttttgttgat ttgctaacag cttaatatgt gctttaggct aaacttcaaa atctctaaca
    28201 attctttgtc ttgtttcatg tcctctacaa ttcatttaag ttctccttta caagtttagt
    28261 aactagcctt attatactat ataagatatg aaatgtacca taatcttcat caactagttt
    28321 ttagaaaatc acaaatccat ctggagagat gacaagctga ttctccaatt cttggcaatt
    28381 gcttgctagt actactgctt ctttctctaa aagataatct tctgttgatt ggttgaatat
    28441 tgctttgagg atccgtcctt cgtatttcca ttccagatct actagatcag atttgatttc
    28501 ttgaaggcta tacttgccat gcgaaatgat tactgacgcg tatttccgaa tcttaatcag
    28561 cctcttcata aagttcagca tatcattgtc acttgataca cgttcccaag gcatacaacg
    28621 acgacaatct ggatctggtc ctccagtcaa ggctagctcg gttccgtaat aaatgcacgg
    28681 tgttcctttt tgtaaaaaga gaaaggctaa ggctgattta accagttgaa catcttcatt
    28741 ggccgtccac aggattcgct ctgtatcatg tgaatccaag agattaaaca tgacctctga
    28801 aatctgctgc ttgtaataca tagactctcc attgatttca tcgatgaact ggtctgtatt
    28861 cttaattcct cgtaagaaat agtccttgat actatcagat aaaggataat tcatgacggc
    28921 atggaactca tctccattta gccaaggctg agatgtatgc cagacttctc ctaggatata
    28981 aagatcagga tttttagcta aaactgcctt acgaaaatcc ttccagaact gatggtcaat
    29041 ctcattagcc acatccaaac gccaagcatc gatattaaac tcttcaatcc aataagtcgc
    29101 aacctttaaa agataattct tgacctctgg attggctgta tttagcttag gcatatagtc
    29161 ctcgaaacca aaaacatgat agggtaagtc tctcttatta actagctttt cagttgtcac
    29221 tgggaattgt tgaatatgga accaatcctt ataagcagac tgttcaccat ttttgacgac
    29281 attttttcat tgaagagatt gcgaaccaat atgattaaat accgcatcca gcatgacttt
    29341 catgccacga tgatgcgctt gatccaccag ttcccgaaag gtctccttgt ctccaaaatg
    29401 acggtcaatt tcaaagtaat ctgtcgtatt gtacttgtga ttgcttgtag attcaaagat
    29461 gggacaaaga tatagtccag taatacccaa gtcttgcaag taatccatat gatcaataat
    29521 cccctgtaaa tcaccaccaa agaaatcatc actcttaggt gtgacagatg aatcccagtc
    29581 taaagtccct tctgggttta atagagcatt gccattggca aatctttcag gaaatatctg
    29641 ataccatacc gtatttgaaa ccccgtcagg aaccttgcag gcatcaatct catgaagata
    29701 aggcaactta aatccattcc caattgcatg aagattttct agagaatttt ccacacaccc
    29761 tttatcgcca tacaaaatat tttgaccttc tgtatctctg agctcaaaga gatactggat
    29821 acgtgcaaag tcaactgaca cttcaacctg ccaatggtca aataaggtac cagaagttat
    29881 cttgaccatt tcttttgtat cctgataaaa ctcctccata aagataaaag ggtccccata
    29941 gtgcaagttg atgctttcaa tgtccccttt cttagttcga attcgaatat ggagtttctt
    30001 atccttataa agataggcat actccgactc aggcccatgg taaatagcac ttaattccat
    30061 caatttgtct cctaaagtat tcattcaaat tttacgcaaa cgttttcaaa ctcaataaat
    30121 ccagtatact atttttgtaa actatttgca aggaatgtcc gttgttaaag gaactatctt
    30181 ttaaagtata caaaaagcct taaaaaaggc tttctctata tactaatcct ctttcggttt
    30241 tgaaaatact tctactcgct gagctaggac tttgatttct acaggtaggt tatctgattt
    30301 atctccgtca acatctgact ccaattcact atctgaagag attttaatat tacgcgcttt
    30361 gatatactcg atattatcat ttgcgataac atcccctttt aataaatcag gaatgacgga
    30421 taatttggag aatatagagg catctttcag aatcaaaatg ttggcatagc cgtccttgtt
    30481 ttcttcaaag attttcttat cagcgaagta atttgtcaaa aggaccaaaa catggctagc
    30541 ttcaccaaca taatttccat tttctgtctc aaccttaatg ttaaagacct gatctgtcat
    30601 gacagacttc atggtattta cagcataggt taaaataccg aattttgttt tgtcctctat
    30661 ttcaacattg tgaatcgcct caggcagaga accgatacta aagatataac caaaatagtt
    30721 gtcatttgct ttaccgatat caatcttatt ggttaaatca aaatccagtt cgtcaattgc
    30781 gccatcgatg tcttgattga tttccaaaag ttttgtaatg aggttacccg taccgcctgg
    30841 gataatccct aacttaggaa tgtagtctct ctcatcaata cctgaaatga cttcattgac
    30901 agttccatct ccaccaaaca caaccactgc atcatactgc tcacgagaag cttcttcagc
    30961 aaaatgtgtt gcatccagcg ctttttcggt aattttggtt tcaacatatt caaagtattc
    31021 ttttgcttta ttctccagct tttctttgta atccaaagcc ttctcgccac cagaagtagg
    31081 gttgataatt accattgctt ttttcattga ttttatcctt aattttaaac agaaatgttt
    31141 acatttcgtc gtatgcaagt aaatgtaatc ctattataca atgaaaatac agaaaagaga
    31201 aatctgacgt actggagatt aatacgcttt tattctattt tcccatcgcc taactacatc
    31261 ctttaagggt tcatccaagt aagaataggc cttatccttg atccaatcag gaataccgta
    31321 agttgcctct gctatgctac aagtgattgc tgcgagagta tcactgtcgc caccaagtga
    31381 gatggcattt cttatcgcat cttcgaagtc tctactttca agaaaggcga taatggcttg
    31441 agggacagtt tcctgacatg tttcgttaaa acgatagtta ggacggattt catctaaagt
    31501 ttgagataga ttgtaatcgt attctttttc tatataatcc ttaattcgtc ttttacactc
    31561 tgtaggattg tcgttaattg attgctcgta ctctctacaa taaccaccaa agtaaaaacg
    31621 acatagaaag atagcatcag ctgtagccat agcgcctttg acaccttctg gatgattatg
    31681 agttacctct gcagaaagac tcgtaagtcc tctagatgat ggccacatac cagttttcgc
    31741 ataaaaacca cagtccatga tccaagcaca tggagaaata cgcatagctg atccattccc
    31801 aaagctatta taaggttcac ggttatcgct gtttagccat gcattaaacc gagcaccgta
    31861 atcagcattc ggatacattc tgccatattt cttcatcgcg tcaatgaaat cgtctttttg
    31921 tccaccattc ataattgctt ctgcaacagc acaggtcata accgtgtcat ctgtaaaaaa
    31981 gcagtccttc cgaaataaag gaaagtcctt tgttttgata ttgttccatt cgtaaacaga
    32041 accgacaata tctccaataa ttgctccaag catcagattc ctccttgttc attttgatgc
    32101 tttttatatt ggttatctac catatttatt ttagaaaata acatcctgtt ggattttaaa
    32161 aatttcattt ttttcaaaat agggttttac catttctttc cacctagctc tatgaaaatt
    32221 gattgatttt aaaggagata ggccataatt tcccaatgca taaccatcat ttacttcaac
    32281 aacaagtgtt ctgccatcgc gagtaacacc gatatctagt ccataagcta ttggcgcatc
    32341 tttccaacat gatatcgctt catcaattac acttgcatca aattgtgcat gataatcacc
    32401 tgtatagggt cgaacatcta atacgcgaac atctaacaca aaacaacgcc attcagctat
    32461 gaattctaca acctcactaa tccatatagg atagtcgaaa ggtagaccaa tacctattaa
    32521 atcatgggtt ccattaacaa ctcttccagt aaagactttt gaaccagctt taggcttaat
    32581 aaattttccc caattatcag gtatattcac aatctctcct aaaataccag cataaatctt
    32641 tcgaccataa aactctttaa gctcaatagg atagtcataa accggaacgt ttaagcccat
    32701 catttttagt aatgctctag tctccattat ataatctaca actatatctt cacttgttaa
    32761 ctcttttatt tcagaaaaag attgatataa aataacttct tctccttgta agtaggcacc
    32821 tacttgagca ttgtatttat taattgaaac ctcacttggt aatttacttt gtctaatata
    32881 aacaaccatt tcatcactcc tatatcacta gtgttacacc aatttgtaaa aataatagca
    32941 attttgctct tatttttttg agtaaatagc ccccataata tcatcgaaat aatcaacggt
    33001 atttaggagt aattcaataa cctgggactt tgttagtcgc attccccttc tatctctagc
    33061 atcttctact aaattttcaa gtttctctag atttttatca tccaaactaa tcattattct
    33121 atttttatcg gttgccattt tcatcacctc aagttaattc tatcacaggt gtaacacttg
    33181 tgtcaactgg cttttataat acattagttt aaaagtggag aggatttttt acacagtaac
    33241 tttaaatctt tggtattaaa aaattttcac aatatttata gaaataaaat ctgtctcaaa
    33301 tcagttatca aatctagtat aaattatgag cggctactct aatactttcc ctctaaacaa
    33361 gaaaaagact tacactcaag gattttcttc ccccccttcg ttataacgtt ttgactcttt
    33421 tactagcaaa ggtatatact cacaaggaac tttggttgac tattgaatct ctccaacttc
    33481 ttctttaaca tatccttcta catcttcaat ctctacaaac attgggtcta agtgacacaa
    33541 gaaatgccaa acttcgatcc ctttttttct gtaaagaatc gcttcaccgt cttcacttcc
    33601 gaaaaagctt ctgtcgattt catatccgcg gctttctaag aagtcttttg ctttacgata
    33661 gttcgtttct cttgtttcga cataggcttt aacttcatgg ttgttaacga catatgcatc
    33721 aatttttgaa tatccttcga tcactctatc atttttgagg gataaatttg aaatctcttt
    33781 ccaaataatg tttacatttt ccccaggatc gaacataaat ttagataaag gaacaatatt
    33841 tccgttaaaa ataatttcca tataatccgg tatgttttta ggattaaaat actccacttc
    33901 aaaaccatct tctgtttcca gagtgtatcc cgggatttga gctacaaagg ctttcccatc
    33961 ttctatggaa tcaaatgcta ctaaatcttt agaataatca ttttggtaca attccaatat
    34021 aaccatcgat aatctctcca ttttcattat caggctaatg taaataagca cgtcacctga
    34081 ccaattcagg ctctctgtat catctcatca tatttcctac ttactttacg agtcctatac
    34141 ccagaacaca ccttatcgac cttcggtctc acctcgtcgc attggctgaa catctacttt
    34201 tactttgctg atgcttcaac tcgtacaagc agtgataccg cctcagcgtg atgcgtcagt
    34261 gggactcaaa aggttcgggg aaccttttga ggattaacta cgtttctcta ataaacttac
    34321 acattcaact tgttcatcat tgtccaaacc tatgttgaga ttttcttcta taattggtag
    34381 cttaaaagta atggatttta gccattgtcc gttagattgt ttttctttat aaacttgaat
    34441 ttcagaaatc aaagctgaaa ttaactgcct acgctctaca tcattcatga ctttatagag
    34501 cttatcaaaa tagatcagaa ccttatatat gttatctcct gtaagctttt cagcttcaat
    34561 agtctgtttc tttgctttcg catcaattag tgatgattct aattcatcta ttttgtcata
    34621 catacgatat agtctatcat ctaaatcctg tttccttctc ttataatgct tatcttcaac
    34681 atctaaatta tctatttcct caattagctt aaactttgta gaatgactct ttctcaattc
    34741 cttttggtaa ttatctattt ctttttctat ttcagaggta tccaccttca tgttgatttt
    34801 ttcttgcatc atagaagcaa atttcggatt acttactatc ttgacaatca cctctgcaac
    34861 agcatcatct aacaattctt ctataatttg cttactgaat gtacacttat gacctcttat
    34921 catctgccta tgtttacaac catagtaata aaaatcttta tactttgtgc catctttctt
    34981 tttcttgata cacttgttcc caaacattcc cactccacat atcgggcatt ttacaattcc
    35041 agaaagcaag tgtgtgcgtg tatcttttcc tttattcaca tgctcatatt tctttgcttg
    35101 agattttagc ttaacctgag cagcttgcca aacttcatcg gaaactatag cttcatgtat
    35161 cccttcagat attagatatt catcttgttc aacctgctta tattcatttc ttgtaccatg
    35221 aactttttct aaagttcttc ttccaaatgc tattttccca ttatatacag gattctttaa
    35281 tatctttctt ataagacctg catcaaacaa aggattctta ccattctgtc ttgggatttt
    35341 tctaattcca tgattctcta agtatttaga tatcccattg gctcctatcg tagtatttac
    35401 atactggtcg aaaatcgttc ttattgcaac tgcctcttcc tcatttataa acagcttgcc
    35461 gtcttcaagt ttatatccat acggagcaaa gccaccattc cattttcctt cccttgcttt
    35521 ttgaatgcga ccttccattg tttgaatacg gatgttttct ctttctattt cagccacagc
    35581 tgataaaaca gaaatcatta gtttcccagc atctttagat gaatcaatgc catcttcaac
    35641 gcagataaga ttaactccat aatcctgcat tatctgaagt gtagaaagaa catcagcggc
    35701 atttcttgca aatcttgata acttaaacac aagaacaaaa gatactccat cttttccaga
    35761 ttttatatct tccatcattc gattgaactg tattctacct tcaatagact tgtcagactt
    35821 cccggcatct tcatactctc caacaatttc ataatcgttg taaatagcaa aagctttcat
    35881 tcgtgatttt tgtgcctcta acgaataccc ctctatctgt attgacgtag atactcgtgt
    35941 atagaggtat acttttattt tttcttttga catagtatta acctcaatat aatttttcta
    36001 tatcatatat aattttttta atttaagttt ggactatcat ttcaagtata ttataacact
    36061 tttattagtc cgtctcaatt tgtgtttttg ccatgtcaaa actatttttc atatcttgat
    36121 tttttgctgg cgttggatcg ggtagattat ctaaatctaa agcaccagca tattttgcaa
    36181 tcagatttgc tattaaatca gccaatccat tccagtcatt gtccaatata tacctcctct
    36241 aaagttttat atctaataat tatttgttta attaagtttt ttgacattga caagtgcttt
    36301 ggattagcaa cataggaatc tcacctccgc ctctattccg gatgagccgg cttcaacctt
    36361 agaagtatca ttatcctcat tttcttcata gcggataggg tatccctccc tatattcaaa
    36421 ctcttactta tcgctcactt tctttttgct tagcagaact ttttttgccg aattattcag
    36481 ccgaaagatc ttgacggata ggttattacg ctccaaaaat aattaacgtc ttgtcttggt
    36541 ctattcaatt gttaaggttc aaaatttatc gagagttatt aatcttttta aaatttgacc
    36601 atcagaaaat atttatcttg atgtaacaaa attctataaa ttaccctctt atacttaaca
    36661 gtgaaaagaa gtctttcttg gtaaccaatt ttgaaataga atttgcttat ataaaaaggt
    36721 tcaattccca ctgcataagt agcagtgaaa attagaccct cttggtaact gtcatctaaa
    36781 agtcttctag catttcttta attttctaat cgcctttaaa gtgtcatatt tatatttttt
    36841 tatctctggc atactttgat acctttttag acttaaagtc tttaatagtg cctttccacc
    36901 tctttttatc tataaagatt ctcctacatc ataattcatt tttttattta aacctttctg
    36961 tcttagtttg tctttatctt cttcatacca ttttaatatt gtcacatagt ggttttgata
    37021 ggtcttacca ctgctttcca tgtatctgga tagtttattt atcattatat ctgtgtgtga
    37081 gtttaatttt tcttttagat ttttatattc ttctttgctt aaccttacat ttttgaattc
    37141 tccataaaaa atgggggtgg actttttatc tatctctccc tctctctctt tatctatctc
    37201 tatatctttc tctatctctt gtcggacatg ggttggactc attaaggaca atgtcctctg
    37261 tttattttgt ctgtatcttc tttttttctc tgcccaggct gtttctgatc cgattaagtt
    37321 tggtatttca gttaggtagt attcatcatt ttctgttaca acttctaata agccttgatt
    37381 gattaaataa tttactgtta ccattacatc atcgtctgtt tcatctatgg ttagtgctaa
    37441 ctcttttata aaatcacttt ctactccgtc ataatagagt ttgccctcat cttttaggct
    37501 tagtagtaga agttttaggt agattatcgt ataggtatct cctccagata ttctccttaa
    37561 cctttttatc cttttgtctg tgaaaaattc ttcttttaat tttatccaat agtatctttt
    37621 gtttgttgcc atatctgctc ctttcttgat tttcgataat cgaaattctt gatttccgat
    37681 tttcggaatt ctggacttct gtttttcgga agtcttgtta ttatggttat ttaagggtgt
    37741 aacttttcgt tactcccttt agatttctct ggtcatatct tttttgtttg gttttacttt
    37801 ttcttttact ttcctttttc ttttgtctta tctttgtttt tggataggtc tttgtatttc
    37861 tttatttgtt tttggatact ttctttttct tttttattta gcctataact attagacttt
    37921 aaagtttcta tttttgtttg taactgacct atggtttcta tgttgttttt tcttaaataa
    37981 ctatatgcac ttgttagctt tttgaagtca tatttttctt tattagtttt tgcatatcct
    38041 tttagatatt tacttttttc tttttgaatt tctgaataag ttaatagata atttgttaga
    38101 ttaaaaagtt tagggttgtc tattacctta tctctttcga tatccttaaa tttttcataa
    38161 gcagtagata agttatctaa taaatttcct atccaaccct ttaatgtttt tatctcttct
    38221 tttattgttt ttacaagttg attatatttt cttatttctc tattatagtt tcccttgtca
    38281 gtttctattc cctttctttc cattgcactt gctgctgatc ctaaatggat tgtcggtaga
    38341 taatctgaat tttgtctttt aaaactccta tggtctactc ttttttctgc tcctgctctt
    38401 tctaaatatt tgttacaaag atctgaaaaa ttttctctcc atttttctac attgcctgta
    38461 tcgttccagg ttgttagttc tacttttctt gtctttggtt ttccattttt gtttaatact
    38521 ttttctcctt tttcatctag gatatattct ttttttgact tggctaagaa ctctcctttt
    38581 tcgtttattg gtcgcattat ggtcattata tgacaatgga tatttccatt tttatcttga
    38641 ctctcatcat gaattgcata atctactatc attccttgtg atgttaaatt ttcttttata
    38701 tatctttcaa ccaggttttt attttcactt aaagataact cttttggtag tcctattatg
    38761 aattgtcttg ctagttgtgc attagaattt ttttctgcca tttctacttt attccataag
    38821 gtagacttat cattaaattc ttttggtata tgatcaggca atattatatt ttttactaat
    38881 attttttctt ttcttgtgta gtcatgggtt actccgtccc attcattttt tattttttct
    38941 ccacttatat atgctgcact tgctactgca cttttgcctt ttcctcttga tattatgttt
    39001 actgaaaaat gaaaactgtc tgccattttt atcacttcct ttctttgttg ttttaggtgg
    39061 aggcttaata gtttttttat atcctctttg tgaatgagcg ttttgaaatg atagaattaa
    39121 aaaagccgac tactgaatta atttttgttg tttcagtatg ttggcttaat tgttactttc
    39181 atttcaaatt ttaaaagtca agggcgagcc ttagcgagtt tatttaccct tgacttttaa
    39241 aaagcgaatg gttgttgctc cctgcaaggg tttgactccg caggacgcaa gcacccttta
    39301 gggtgtataa ttgcgccctt gtaaccaagg gacaattatg ttatttcatc tttagatgat
    39361 ttttctacat tatcatctat tctttcttct aaaatttcca ttatgtttaa tcttatttct
    39421 tcatcattta acgtttttat taacttataa aattcatctt ttgttaaatc aatactttct
    39481 tcaaaaatac tttcaaacac tgcacctttt tctataagtc ttttgtttct tgcttttctt
    39541 tcttgttcat taagtttttt cttcaactgt cttttttgat tttgtaattg cttaatgctt
    39601 tcttctttct tttcaatctg ttcttcaata cttaatcttt tacttgccat catgtatcct
    39661 ttcttaaaat aaaaaacgac tagattttta tttctaatcg ttcttgtttt aaatattata
    39721 atttgctata ttgcatttta attttaagtc ttctatatat ctttccatgt aattccaatc
    39781 tggagtacct ctactgtcta tcggtaattt aattttgata tctggcaata ctgtgctaga
    39841 tatttgatct ttatattcag tattttttaa agcttgccta ataattgaag ttaaatagaa
    39901 tgctacttct ttattcaatt ctttattttt taattttaaa caatgaattt tcatatctag
    39961 gcttgcttta tatttatgat aaaagactgc tcctaaaaat gaaacagata taaaattttc
    40021 aaagactcta taatttttat catctatatc ttcgtagtaa cctaagatac cattgtcaat
    40081 atttgtagca ctaattctag gagtttttcc atcgagtaaa tatctttttg gaatagatga
    40141 gcctgttggt acttaactcg atttcccctt tttttcggta ataaatattt ctttttattt
    40201 tgttgtctga tatttttcct acctgtcctt tgtaggatga gtattttcta gattttcttg
    40261 aataactttt tacttgaagt tttagctttt gaactagtcg ttgtactttc tttttgttta
    40321 ttatcagtcc tgatcttttt aatattgctg ttattctcta tatcctattt ttcattcatg
    40381 atattctttt actaatttta tcttaaattc tgtgctgtat ttgccattaa aaaactgacc
    40441 tcctttagtt agttttttgg cctaactttt gagggtcagt tcaaaatttg cgacttttaa
    40501 atgaattcca atattcaatt attaagagtt aacatggtgc ttgccaatag gaatcattag
    40561 aggcgaattg gaaatagggt cacgtataat ttttgcttca agattaaaga tatctttaac
    40621 tagtttatca tttagtatat cttcaggctt tccctctgca acaagtttac cttctttaat
    40681 tgcaaatagg taatcagcgt atcttgctgt tagatttata tcgtgcaaaa tcatgcaaat
    40741 ggttgtctta tatttttggt ttagatcagt caagaggtct aatagttcta tttgatatga
    40801 gatatccaag taagtagttg gctcatctaa aagtaggata cttgtatctt gggctagggc
    40861 tagagctatc catactcttt gcctttgacc cccagaaagt tcttcaacta ggttatttgc
    40921 tagatcttca acattggcct taaccattga tctgtttatt atttcaaggt catcttttcc
    40981 aagactctta aaaggctttc tgtaggggaa acgaccacgg cttacaagat cagctactgt
    41041 tattgattca gggattattg gagattgagg taatatagct atgtgttttg ctaaatcttt
    41101 ttctttataa gaattaattg atttattatc aagcaatact tctccctcta atggctttat
    41161 aagtcgagac aaggttttaa tgagtgttga tttcccacaa ccatttgacc caataataac
    41221 tgatattttt tcttcaggta tttttatatt tatattttcc aagattattt tttcatcata
    41281 accgcaggta agattatttg accacagacc tttcattata tattcctcct gttcattttt
    41341 attagtaagt atattaagta tggtgaacct aacaagccag ttacaacacc tactggatat
    41401 ctagctggta aaatattttg agagaatatg tctgataaca aaactagtaa aattccaacc
    41461 aatccagcta atattgggct tcttttcttg ccaatattta aggctatggg accagctaaa
    41521 aaagatatac aagctattgg tcctgtaatt gaagtagaaa aagcagttaa agatacagcg
    41581 caaaaaatta aaacaagcct tgaaagctcg ggatttgctc caagtccgat tgctatttct
    41641 tcaccaagtt caataatttc tagtctttta ttaaaaaata aaactaatat agtagcaata
    41701 atacttacta ttagaacaag aggtatgtca tctaactttg taaaagataa agagccactg
    41761 agccatctca taacttcttg taattcatat cttgctactt tcaacaataa aaatgaggtg
    41821 cctgctcttg tgacagcttg aaaaccaata cctaatatta tcagtcttgc tgctgaaaaa
    41881 ccatcttttt tagctagtaa aaataatatt aaagatgatg ttagtccaca agttattgaa
    41941 ataattccag tagttaaact atttgttttt aataccaata tgcaaaagac cgctgcaata
    42001 gatgaagaac ttgtgacacc gattatatca ggacttgcaa gaggatttct taacatagtt
    42061 tgaaagataa atcctgccaa tccaaaagac cagccagcta taattcctgc taataatttt
    42121 ggtaatctaa tttccataat cgaaaaacta gctccaggaa cagtttcact atttaagact
    42181 ttaatcaaag ttgaaaaaga ataactttca tctccgataa gtaaaatgaa aaatgataga
    42241 ctgattatta ttaataaaaa tagtgaggaa aatagtgtta ttctattttt tcttttttga
    42301 atacctataa ttaaattttg cattagttat taacccctct atttttcata gttacataaa
    42361 taagtactgg acccccgatt attgcagtaa ttatccctac ttcaatttca cctggtttac
    42421 ctaacatacg gccgattata tcacatataa gcaagagctc tgcacctata aaagatgaag
    42481 aaatggtcat tgtgcgtata tctttgctta taaataagcc acaaaagtga ggaactataa
    42541 gacctacgaa gccaataggt ccaccaattg cagtaatact tgaacataaa agcacacttg
    42601 caattattgc aagtgatctt atcctattaa cattaactcc aagaccaaca gccatttcat
    42661 cacccatagc taaagcgttt aaatctgatg aaataaatat agctatcaag tgacctaaaa
    42721 ttataaaagg tagtagtgta gatatagaag ataatgtagc tgctccaagg ctacctattt
    42781 gccaaaatct aaatttgtct aagacgttat tattcggtaa aattaaaaaa cttacaaaac
    42841 tgcttaaagc catactaaca caagttcctg ataaggcaag ttttataggg gtaaggcctg
    42901 cttttccgct tacagcaatc gcgtatacaa aaattgcact tactaagcca ccaatgattg
    42961 caaaacttat atggcttatg cttgatgaaa ttcctaaaaa agaaagacca attactacac
    43021 taagacttgc tcctgtgttt ataccgagta tacctggatc agctattggg tttctagtaa
    43081 ctgattgcat caatacaccg cttatggcaa gactagaacc tgctaaaatt gcaaaaatag
    43141 ttctaggtat tcttttatat ataattgatt taataaaatc atcatttgta ttacccattc
    43201 caaaagctgc taaaaaatct ctgatattaa tttcttttgt tccaagcttt aatgacaaaa
    43261 atattgtaat aagaagacct aggcagatta caaaaattat gcctaggttt atttgttttt
    43321 tatttcgcat ttttgcatgc atttcctaaa agatttagat attcttcaat agtatagttt
    43381 attgaaagtg gtgttggagt gcatgaggct gctaacggtg tattatctgg aattacagca
    43441 acggcaccat ttttaattgc atttatttta cctaaaagag gatctttttg taaagcttca
    43501 agagttttat catcaccata agttatgatt acatcagcat catttatctt atttgcttct
    43561 tctgcagaaa tttcctttgc aaaactatct tcactctcaa attcttttaa tgattcaggg
    43621 aaaactagac ctaaatctgt taaataattt gctcttggat ctttgctagt ataaatccag
    43681 aattttgatg tatctgcagc attaatcata gtaaataata ctttttttcc tttgattttt
    43741 cctttgattt ctggatgttt ttctaattct ttggatatac gagcttcagt atttttgatt
    43801 aactcatcac cttctttttc catacctaag gcttttgaat caattttaat catatctctc
    43861 cataaagttt gccaaggttt agatttgtat gctgctacag gagcaatttt tgatagagtg
    43921 tcataatctt ctttagttat accagaataa cctgctaaga taacatctgg tttagaattt
    43981 gatattgctt caaagttaag tccatccaaa tcgtcaaata ggttagcttt accatttagt
    44041 tctttgattt tttcttctgt ccatggtaaa actcctttat cagcacttac accgtaattt
    44101 gcttttgaaa atccaacagg aactattcct aaagctaatg ctacatcatg atttccccaa
    44161 gcaatagttg caactctttc aggtttttta tctaatatag tttgaccgaa agcatgatct
    44221 aaaactattt tatcaggcgc atgctcttta gaagtatttt cttcattttt aacagaatta
    44281 gaagaacaag cgctaaaaac tatacacata gctaaaatag ctattagaaa aaatttgttt
    44341 ttcataaaaa ctccttaaac atatttcaag tctattgtat cgataataat tatcattgtc
    44401 aatagataca gttacaaatt taataatata attttttcaa aaaaggatct agtttttatt
    44461 tttagttaaa ttatgtctat atttttcatt aactcatcaa taaaaatttg tttgctaata
    44521 tctctttctt ctgattttgt ttcaaggatt attgctacat cattcatatt tttaggtaaa
    44581 taccaaccat ctggcttatc tgaatatccc ttgaagccta attgattaaa agtagttatt
    44641 tgaccagtac cttgattgat gttttcttca acttcattaa agcctatact tctcttgcat
    44701 aatccctaac ttgatcttct gtccttaaag tcattttcta ttcctcgtca ctaaaattat
    44761 cttcaaaact aataatatca ttaggagtgc aagataaagc cttacatatt ctttctaaat
    44821 tcttaaatgt aattggttta tcctttccca tttgtgccat aacatttgtt gtaagtcctg
    44881 ccatagctat tacatctgtt ttctttagtc ctttttttgc taactgtatc cataatggtt
    44941 tatagttaag tgccataata tccctctttt tttcttcatt agatttattt aattatagca
    45001 taaatattga tttcattcaa tcttacattg atttagtgat ttgttttaga gaatttgttg
    45061 tgttattccg tccttatttt gccataaatt gttttaagtg ggacctctta tccttaccat
    45121 ttttacctcc taattttgag tataaaaaag acgatagagt ttttaatttc tatcgtctga
    45181 gatttacata ttaaattttc atcacaaaat aagactcttt aaagaatctt taaattcatt
    45241 ggtatgctaa ttacaatatc cattattaaa atggatacta taagcagcac accaactatt
    45301 tattttttga gttttaaact ttggtagaag tcttgaactc cttatattta cataactatt
    45361 tgcctctata actattatga cacgaaacca acaagcaagt tcaagcacct ccatatcttt
    45421 attcaaatga ggactaagat attcacaaac tttatcataa acctctttat cttttttcat
    45481 aaaaggggca tacaacttag caaatttatc ctaaaatttt ttgttgcctt tatcaatcat
    45541 ttcaacactc ctttaaatat aaaaatgatc ctatcaatct ttatattgag cctattttct
    45601 aattgatacc ttgcaagaaa ggaataatag ctgttcctat accaagtagg aatgtaataa
    45661 atgcagaaag tcatatactg tcattctttt ctattaaatc attttgaagt gtctcaaagc
    45721 atccatgatg gcttcttctt tttcaggtgt acactgtgga ataatttgtt tatccttttt
    45781 agacttgttg taatgttctc gtaattctat tccacatttc ttttttatct gtgcaatata
    45841 taatgtcgaa acttttaatt caaatttatt ccaaacatat tctttgattt gagcatatgt
    45901 tgctttgctc tccgcacttg tcaaattcat ctcatccagc tcaatttcaa cacttatgtg
    45961 cttatcgaca tcgagtttgg acaaaagtgc taccgtctcg acgtgatgcg tttgaggaaa
    46021 tagatccacc ggctggactt tcttcaattc atatcccaat tcttggtaga gtttgatatc
    46081 acgcgccatg gttgcgacat tgcaggagat ataggcgatg cgatcggctc ctgtttgggc
    46141 gcttgctttg ataaagcttt ctgtcaagcc cttgcgtgga ggatcaacca agataacggt
    46201 tggttgaatc ccatctttaa gccaattctt catagcattt tcagctgtgt cacagacata
    46261 gtgggcgttt gaaatattgt tcagctgagc atttttttta ctattctcaa ccgcttctgg
    46321 aatcagttca acaccgtaga cttctttgac atgcttggcg actgataaac caatggttcc
    46381 aataccagaa taggcatcaa taatcacgtc atcttttttt aactctgcaa agtcaatggc
    46441 tgtttgatag agtttctccg ccatttcagt attgacttgg taaaaggctg ggccagcgat
    46501 ttggaagtca tttcccaaca tctggtccgt aatatagtct tgaccataaa gagtgcgcca
    46561 ctccttacca aaaatcgcat tggtattctg gtcgttgata ttttgcatga cagacacaat
    46621 ctctgggaac tgcttgataa cttgttcaat caattggtca acacgaaaaa cttttggacg
    46681 agttgtcacc aaaacgacca tgatttgtcc tgaatagtga ccacgacgca ccacaagatt
    46741 ccgaatcaat ccagactgtt ccttttcgtc ataaggtttt aaatcaaaac gacggagcag
    46801 gtctcgaaga gctactacga cttggtcaat gacaggatcc tggataaaga aatcttcaag
    46861 gggcatgagg ttgtgcgaat tcttacggaa aaatcctgtt tccaagacac cattcactcg
    46921 acgaacgggc acctgcgcct tattgcgata cttgactgga tgttccatac caagcgtttc
    46981 agcaacttct acatctgcaa ttccagcaat cttgtagaga ctgtccttga cttgcttggt
    47041 tttaaacttg agctgttctg gataagaaag gtgtcctaaa tccgcgattc ctgaacgcag
    47101 gtaagccaaa tctagatctt gattacggtg tggtgactgg acaaggtatt tttcaacttt
    47161 tccaaagcca atctttttat tgaccttgag gacacgcatg agaatttttt cactcggtaa
    47221 agcattctct acaaaaaaga ccaaaccatc taccttggca actcctgccc cttcatgggt
    47281 caagtcaaca atttcaactt ctacaatatc atttttcttt aacattcttt tctctttcta
    47341 ttggccgaca aaaaagacgg caacgttacg gttaccatcc attataccat gaaatttctt
    47401 aagaaccaaa actcttgaag aagttgacaa gggcttgcca gagggagctt aagaagttac
    47461 caccgtcctc tagcgcctta tccgcatcaa agttaaggtt gatattttta aaactgtcgc
    47521 cagcttgtga tacgatgctt tgtttaaggt catttagggt tttagtgaaa tctgcattgc
    47581 tgaggatatc actctttgag agattcaagg caaaattgat gatgatattg atctggtttc
    47641 ctgttatgac ctgatcaagt ttgtaatttt ttaaggtatc ttcaacaatc ttgcgtacat
    47701 cttcttctgt cagatttccc ttgctttctt tagctttggc gagtcctgac ttgatatcag
    47761 ctagggcaac gtttaattta ttagcatcat agcctgattt gtccttgttt tcagcattga
    47821 tatctgacaa agcctttagc tcttcttgag ccaaatcttt attggcttgc ggcaccttgg
    47881 ctccattagc ttctagcgaa tagtagatcc cagccaaagc actctcacct gtaactggaa
    47941 taggggctgc tacagtgatt ttggcatgtt ccatacccag cgttactgct gcgtttcggt
    48001 acatatcctg agtcacctta gtgatatttt ctggtgtttc aatcttgacc tcaagtggcg
    48061 atttgtcacc tagcttttga atcttggctg atgaatacaa ctgtaagcta gagtcattgg
    48121 ccacattcat gattttagaa taaacatcag gtgtcatggt cttgagttct ttggtatctg
    48181 ttgaggcatt gtagcccagt tttttaagag tttgattttt ttggtcttca gatagggagg
    48241 aacctaggac atattcaggt tggacatagg tttcatcgat aactttttga acatctgttg
    48301 ctgcatgggc gctattcata gctgttactg cccacaagac cgcagcactg gtcagaaaga
    48361 gtttctttct catagggaat ttcctccttt acttttctag agtaatatat ctatcttaaa
    48421 gaaaacttat aacaaaaaca cctggtctag ccagatgttg aaaagagagt gaaacatttg
    48481 atgatgtaaa ggttaagtcg tacctgtcta gaataataat agtttcctcc atttacatag
    48541 agttcagcac cgtgaaaaat ggaaatgggg tgaatataac tataagtctt tccagtcgta
    48601 ttaccaagca agggggcaac agtctcacga gagtactgtt tggctagagc caaggtattt
    48661 tccttgccat tttgggcgat aaaatcgata taggcaggtc caaaattata ggcttgaaca
    48721 gctgtccaga tatctacacc cttcttctgc gccagataga gattgcctgt cagagtttga
    48781 atgccttgcc gaatgctaga ggcattatca ttgatggtat tggtggaacc acttgcagac
    48841 tcactagact gcataacatc gccttctttt ccttttgttt cagtataaat catagcaagc
    48901 acaagctctt cgtttgctgg ggtgtctttt tcactcaata tttctcgcac catgggttga
    48961 taggtcatga cttgtttgac atcttgatga acgcggtaag ctttatatcc agcaaaaagg
    49021 aagactgcta gtacaagcac tcttcgaatt cgtttaaaca ttatttactt tggatatcct
    49081 cgatattttt gattaagata gagtaggttc cattttcgtt ttggataaac tcaacagact
    49141 cggcgtcttg atagacgtta ttgggaacga tgagctcaat tccatttgat aaggagagtt
    49201 tttggttttc aaatttcttt aattggcgac tggcatcaat ttcatcaaat tgaacaggtt
    49261 ctggtacggc ttctttgact tggtcaataa agctcaaacg agccgtcaga ttgttgtcaa
    49321 aaaggtcatt agccaatttc tcaggtgaca attcattgct ttcttctagg ttgttgaaaa
    49381 tagctgattt gaccttggat tgaaattgaa aatcatctgt gttaaaagat tcagcaattc
    49441 tctgggctgt tttttccagt tccttgatag attttttagg agaaatctta ggagcgacag
    49501 caagaagatt atctgaaaaa tagttcaaaa aagtcccgtt gtacttgatt cgtttttcaa
    49561 tcaggtgata cttgctactc tgaagattga ccaccaaggc ctcatcagct cctgttccaa
    49621 atccaggcag gttattctga gttagcttga ttggattatc aacttctcct ccgaggtggg
    49681 tcaaggtctc ccgcagggca attcgcaaga aagcgaaatg ttctacacct tctttagaaa
    49741 attgaacaaa aatcaagtca ttggtcttga gattttcaga aatgctaaac tcctctttcc
    49801 agagattagc cagcgttact gatgtctcca acaaatcgtc tgtaatatga ttgaagaagg
    49861 gattttcttc ttcgaaaatc ccagtcttgg cttcatctga atacacatgt tcaatttttt
    49921 tacgtaggta ttcttcgatt tttggagtaa tattgagaaa cttatctgct aagaacagct
    49981 cggtatcatc cggactgaac tggtgaataa tggctttctt aatataaatg tccataaaag
    50041 ttttattcct cgtataatgg gaaggcatct gtcaattctt tgactgcact tctcacttct
    50101 tctaatacag cctcattttc tgaattctta agggttttaa tgatgagttc agccactttg
    50161 cgactttctt cttcaccaaa tccacgtgca gtaatagctg ctgctccgat acgaatccca
    50221 cttgtcttga atggtgacaa gctttcgtaa gggattgagt ttttatttaa ggtaatattg
    50281 acttcatcca acaagttttg agcaactttg ccgttttcta caactttagt cacatcaaca
    50341 aggaagagat ggttttcagt tccacctgaa ataatacgga aatcagggtc ttgcaagaag
    50401 acatctgcca tagccttgct gttcttaatt acattggcag catattcctt gaaggctgga
    50461 tccaaaactt ctttgaagga aactgcctta gccgccacaa catgctctaa aggaccgccc
    50521 tgaatacctg ggaaaatagc tgaattgatt tttttagcaa gttcttcgtc attggtcaaa
    50581 atcaaaccac cacgaggtcc acgaagggtt ttgtgggtcg ttgttgttgt gatatgagcg
    50641 tatggaactg ggcttggatg aaggccagcc gcaaccaagc cagcgatatg ggccatgtcc
    50701 accatgagct tcgcaccgac agcatctgcg atttcacgga attttgaaaa atcgataatt
    50761 tgagaatagg ctgaagcacc agctacaatc agttttggtt ttacttcttg ggcttgtttc
    50821 aagatagcat caaagtctaa gagttccgtt ttaggatcaa cactataaga aacaaagttg
    50881 taggtttgac cagagaagct aacaggagcc ccatgagtca aatgaccacc tgatgccaaa
    50941 tccattccca taaccgtatc acctggctca atcaaggaca tgtaagccgc acagttagct
    51001 tggcttcctg aatgtggttg aacattggca aatttagcac cgaaaatttc ttttgcgcgt
    51061 tcaatagcaa gagtctctac aacgtctact acatcagttc caccataata acggcgtcct
    51121 gggtaaccct cggcatattt atttgtcaag atagaccctt gagctgccat aacagccttg
    51181 gaaactacgt tttccgaagc aattaactcg atattatttt gttggcgttc ttcttctttg
    51241 gcaatagcat tccagagatc agcatcatat gctttaaaat catctttgtc aaaaatcata
    51301 ggtcttctcc tttattgtgt gactagtcca ttagtttgat tttacaataa gaaaatcaaa
    51361 ctaacagatg cgaataaacc gtttctgcat tttatcacaa gtatagccaa ctttttcata
    51421 aaatgcatga gcacccagac gatgattggc agaatttaag cggataaacc cataaccaca
    51481 tctttttgct tcttcttcca acccttgtag taaactttta ccaatacctt gaccttgcgc
    51541 ttgaggtgaa actgctaaag ctaagatatt aaatcctgct ttggaataga gtgattcgta
    51601 aacttcagcg tggacatatc caagtaagac atgattagct gcatcctcat agccaagtag
    51661 gaaatgatgg gaatcctgag acagtctagc tagttggcta gccgtttcct ctggactaaa
    51721 agtataaccc aaagcctctt ggttgatgtc acatatcgct ttcacatctg tttcttgcaa
    51781 atctcttagc atttcaagcc tcctcaaaag aaatctctga caaccgagca agaatatctt
    51841 ctcgtttaat tgcgccttgg cgtaagattt tcaccttgtc tccagacaaa tccacaatag
    51901 ttgaatcctg tccagttaga aaagcatcgt cttccagacc cagaacctct tggtcaaaat
    51961 ccttcagaat ttgttcaaag gttacaccac ttgcctgacc tgagatattg gcagacggcc
    52021 caatcaaggg acctgtctct cgaattaaat ccagtgtgat agggtgactg ggcatccgaa
    52081 atccaatagt tgcaaggtca gaatttaccc aatagggaac tcggtcattg gcttcgagaa
    52141 taatggtcaa gggacctggc aaaaaggtct ctacaagttt ttgtagataa gctggctgat
    52201 tctttgaaaa gtgcaagatg tcctcgaaag aggcgatatt gagattgagt gccttatctc
    52261 taggacgacg tttgagttgg taaacatggt caactgcttt ttcatctaag gccttggaaa
    52321 aaagaccata aacagtctct gtaggtagaa cgacagctcc acccttttcc aactcttgtc
    52381 taatcctgtc catcatcaac cacaaccatc ctattttgac caaattggtc tttgagtgtt
    52441 cgaactcttt tttcaggaag atgttttcta aaaagttcgg gaacactttg accttgcttg
    52501 tatccaattt caaggtaaat cttaccacca tccttgagat agtcttttgc atcttccgca
    52561 attctacagt aaatagctag gccatcctcg tctgcaaaga gagctagatg aggctccgaa
    52621 tgcaaaacat tcaagcctac ctctgactca tcttcacgag agatataggg tggattggat
    52681 acaattatat catatttttc agaaatttct gcaaaacaat cagatttttt aaaaaatata
    52741 ttaagatttt gatcgctagc attctctgat gcaagctcta aggcctcttg agaaacatct
    52801 gctgctgtca ctgaccaatc tggtctattt tttgctagag cgagagcaat agctccacta
    52861 cctgttccaa tatccagaac tgagagattc gtctcaagat tttcagttag aataagctcc
    52921 actaactcct ctgtttctgg acgaggaatc aaaacccgtt catccacctt taaatgcatt
    52981 ccataaaaat ctgcctgtcc aatgatgtac tgagctggct tgtgagctgc tagttgctgg
    53041 taaatatctt ctacaaattg tttttcttcc tctgttgtca cctcctgctg gagggcaaaa
    53101 ataaagtctg taaaagatag atttttcaga ctacgataga caaaagagag gctttccgct
    53161 tcctctcctt gtcttatcaa ctcttcttca aaatttgaaa ataattgagc taatttcatt
    53221 atttgtttaa ttcttctagt ttttgtgttt ggtcataaag caccaaggca tccacaactt
    53281 cgtccaattt accagacaaa atcgtatcta gtttttggag ggtcaagccg atacggtggt
    53341 ctgtgacacg gttttgtggg aagttataag ttcggatccg ttctgaacgg tcaccagtac
    53401 cgattgtcga cttacgctca gcgtcttgtt catcctgagc aatctgagca aagtggtcag
    53461 cgacgcgtgc acggataatc ttcatagcct tctcgcggtt cttctgctgg gtacgttctt
    53521 cctgcatctc aaccttgata ttggttggca agtgaacgat acgaacggca gtcgcaacct
    53581 tattgacgtt ctgtccacca gcaccagagg cgtgatagat gtcgacacga aggtcttttg
    53641 gatcaatgtc gtattcaacc tcttcaactt ctggcataac aagaactgtc gctgtcgaag
    53701 tatgaacacg gccttggctt tctgtcacag gaacacgttg cacacggtgg gcacctgatt
    53761 catacttaag cttagagtat acagactgac ctgaaaccat agcaaccact tctttaaaac
    53821 caccgacacc attcatagag gcttccatga cttcaaagcg ccaaccttgg gcttccgcat
    53881 acttttggta catagttagc aaatctccag cgaaaagtgc cgcttcgtct ccaccagctg
    53941 ctccacggat ttcaaggatg atattcttgt catcgtttgg atcctttgga aggagcaaaa
    54001 ttttcagttt ttcttcatat tcttcttttt cagccttggc atctttgagt tcttgcttgg
    54061 ccaattcttc caagtccgca tctccgcctg attccttaat catctcttcg gcatcgacga
    54121 tattttgaag gacttgttta tactcacggt aggctattac ggtgtcacga ttggaagctt
    54181 cttcttttga aagctccata aaacgcttgg tgtctgaaac gacatcaggg tcactcagca
    54241 attctcctag ttcttcataa cggtcttcta cagcttgtag ttgatcatag atgttcattt
    54301 ttcttcattc tccttattga tttcaggggc aaaataatgt ttacggcaaa ccgagatata
    54361 ggtttcatta ccaccaatct ggatctgttc tccatcgtaa acgggcagtc catcctgtgt
    54421 tcgcaacacc atggtcgcct ttttcttgca atactgacag atggtcttga tttcgtcaat
    54481 cttgtccgct aaaagcaaga gatatttgga accttcgaac aattcattgc gaaagtcatt
    54541 tttcaagcca aaagccatga cgggtatgtc taactcgtcc acaacacgag ctaggtcata
    54601 aacatggtgg cgtttgagaa actgggcttc atcgaccaaa acacagtaag gtttttctgg
    54661 taggtctcgg atatagccaa agatatccgt tgtttcctca atcgcaaggg cagggcgttt
    54721 catgccaatt cgactcgaca catagccaac accgtcacgc gtatccagag ccgaggtcat
    54781 aatgacaaca ccttttcctt gctcctcgta gttataggcc actttgagaa tctcaatcgt
    54841 tttaccagag ttcatggtcc cataacgata gtacaactgt gccatgtttc ttgcttcacg
    54901 tccatttcta aatttttgct acattctagt atatcataat tttcttaagc tttaaacggc
    54961 aaaatgtggt aaaatagaag aaatcaaaaa ctagtggagg aagctattat gccatttgta
    55021 cgcatcgatt tatttgaagg acgcacgctc gagcaaaaga aagctcttgc taaggaagta
    55081 acggaagcgg ttgttcgcaa cactggagca cctcaatctg ctgtccatgt catcatcaac
    55141 gacatgccag aaggaactta cttcccacaa ggggaaatgc gtaccaaata agctagctta
    55201 agcagaattg cttaggcttt ttcaatctcc aagtagcatt cattgaagaa atatcctaaa
    55261 tttgttacaa tttgaaaaga aacttggaga atttccaaga aaagagcaat taattaaagg
    55321 aaacattatg attacacgtg aatttgatac catcgctgct atatctactc cactaggtga
    55381 aggggctatt ggtattgtcc gcctgagcgg aacagacagt tttgctattg cgcaaaagat
    55441 ttttaaagga aaagacttga acaaggttgc cagccacact ctcaactacg gtcacattat
    55501 cgatcctctg actggtaaag tcatggacga ggttatggtt ggggctatga agtctccaaa
    55561 gaccttcact cgtgaggata ttatcgagat taacacccac ggtgggattg cggtgaccaa
    55621 tgagattctc cagctagcta tccgtgaggg agctcggttg gcagaacctg gtgaatttac
    55681 caaacgtgcc tttttaaacg gtcgcgtaga tttgacacag gccgaggcgg tgatggatat
    55741 catccgcgcc aagacagaca aggccatgaa cattgcagtt aagcaattag acggctccct
    55801 ttctgacctc attaacaata cccgtcaaga aatcctcaat acacttgccc aagttgaggt
    55861 caatatcgat tatcctgaat atgatgatgt tgaggaagct actactgccg ttgtccgtga
    55921 gaagactatg aagtttgagc aattgctaac caagctcctt aggacagccc gtcgtggtaa
    55981 aatccttcgt gaaggaattt caacggctat cattggacgt cccaacgttg ggaaatcaag
    56041 ccttctcaac aacctcttgc gtgaggacaa ggctatcgta acagatatcg ctgggacaac
    56101 acgagatgtc atcgaagagt acgtcaacat caatggtgta cctctcaaat tgattgatac
    56161 agccggtatt cgtgaaacag atgacatagt ggaacaaatc ggtgttgagc gttcgaaaaa
    56221 agccctcaag gaagccgact tggttctact agtgctaaat gccagtgaac cactgactgc
    56281 gcaagacaga caacttcttg aaattagcca agataccaat cgcattattc tacttaataa
    56341 aaccgacctg ccagaaacga ttgaaacttc gaaactacct gaagacgtta tccgtatttc
    56401 agtccttaaa aaccaaaaca tcgacaagat tgaagagcga atcaacaacc tcttctttga
    56461 aaatgctggc ttggtcgagc aagatgctac ttacttgtca aacgcccgtc acatttccct
    56521 gattgaaaaa gcagttgaaa gcctacaagc cgttaatcaa ggtcttgagc tggggatgcc
    56581 agttgatttg cttcaagttg acttgactcg tacttgggaa atcctcggag aaatcactgg
    56641 ggatgctgct ccagatgaac tcatcaccca actctttagc caattctgtt taggaaaata
    56701 agaaaaatcc atgatccttc attcggtcat ggattttatt gtctttatta gtaatctggt
    56761 cttaagaccc ctgttacagt tgccttagtt gcttcgtagt cgccatctac gacaaccttg
    56821 ataatgcgtt tggcatcttc ttctggtgct ggaacaagag gtagacgagt gggtccagct
    56881 tcaaatccca tatagttaag aactgcctta actggagcag gacttggata agagaagaga
    56941 gcattaacct taggaatgaa tttacgctga attgctgcgg ctttcttcat atcgctttct
    57001 gcaatggcag taaacatctc gtgcatttca tccccatttg tatgagaggc aacagaaata
    57061 accccatccg ccccaaggtt catggcatgg aaagcatctc catcctcacc tgtataaatc
    57121 aagaactctt caggcttgtg ctcaatcaag taagccatat tagccaagct agtacattct
    57181 ttgacaccga taatatttgg atggtcagcc aaacgaagca tggtttctgg agtcaattcg
    57241 acaactacac gccctggaat gttatagata ataattggta ggtcagaagc atctgcaata
    57301 gccttaaagt gctgatacat cccttcttga gaaggtttgt tgtagtaagg aacaatagca
    57361 agcccagctg cgaaaccacc aaattccgct acttctttga caaactcaat agagtcacgc
    57421 gtatcattag tacctacacc cgcaatcaaa ggaacgcgtc cattgacaac cttttgtaca
    57481 gccgcaaaca actccaactc ctcatcgtgg gtcaaagttg gactctcagc agtcgttcct
    57541 gcgagaagaa ttccatccgt atgatgggcc aataaatgct caatcaaggc tggaatagca
    57601 tcaaagttaa tggaaccatc ctcatggaag ggggtaataa aggctgtaat gattttacat
    57661 tcttttaaat cttgataaga cacgaaaaca cctctctatt tcaaagaagg agttcatctg
    57721 aactcctaaa cgatatgact attttaattc aaatttcaat tcggctgttg gacgaaccaa
    57781 tccacgttca tgaagagttt cagcaatctg aactgagttc caagcagcac ctttgagaag
    57841 gttatctgaa acaacccaca tgtgaattcc tttttctgca tccatgtctt tacggatacg
    57901 accaacaaag gtatcacgcg aaccaactgc attgatagct tgaggataga tttgatgagc
    57961 tacatcatct tcaagaacag cacctgggaa ggctgcgata gctgctttta cttcttcgat
    58021 tggagccact tcttttgttt cgatataaac agactcagag tgagctgaca agactggaat
    58081 acgcacacat gttgcagata ctgcaatgct atcatcttcc ataattttct tagtttcctt
    58141 ggtcatcttc atctcttcgt acgtgtaatc attatcagtg aaaacatcaa tttgtggaag
    58201 agcgttaaag gcgataggat aatgtttctt gtcaccacct gaaggcaaga tttccgcatg
    58261 caaatcacgt ggtttcacac catcattcaa gacttcacga agttcacgtt gtgtctcaag
    58321 aattgctccc ataccagcac ctgaaacggc ttgataagtt gaaacaatga tacggtccaa
    58381 gccccatttt tggcgaaccg gctcaagagc caccatcatt tggattgttg aacaattagg
    58441 gcaggcaatg attccgttgt gagcatcaag tgcatgagca ttgacctctg gaacaaccaa
    58501 aggaacatct ggattttgac ggaaataaga tgtattatct actactacca cgccagcttt
    58561 tactgcgtat ggtgcatact tagctgatgt agaactacct gctgaaaaga gagcaatatc
    58621 aactccttca aaagctgttt cagtcgtttc ttcaattgta atatcttgat ctttaaattt
    58681 caatgactta cctgctgaac gtgcagaagc aaggtaacgg attttatcga ttggaagtgt
    58741 tgattcttcc aacattttta tcatctgagc accgacagca cctgtcgcgc cgactacagc
    58801 aactgtatat cccataaata acctctttcg gaattttcta aaaatttcta taatagaagt
    58861 attatactac tttttccatg aattgcaaag ctttttcatt attttttgga aaataaaaat
    58921 cccagtcgct agactaggga ctaagaggca tcttcatgtg atgagcaggt tcacacaact
    58981 catcaaggtc cgctcctgcg ttatgacctc cttatgctca atagtagtcc gaagactacc
    59041 tatcgactca tcgcatattc tatattacta gagatacttg attttgtcaa taagaaattt
    59101 tttcgatcga gtataacaaa aaactcttgt attcaagagt ttccctatac atatcatgct
    59161 aattgccggg attgaaccgg cgacctcatc cttaccatgg atgcgctctg ccaactgagc
    59221 taaatcagct tacttaagaa gtatactata atcagaaaaa cttgtcaagt ttccttagaa
    59281 attttccata ggaaaaagcc aggtaagaac tacctagctt atcttcttct atttacttaa
    59341 atcaattcga cgaccaattt taccaataat aatcgctcca ataatcaatg aagcaaattc
    59401 accgattcct gttgtaaacc aagtaaggaa gaatggtaat tctgctacaa tatttaactc
    59461 tgcagcgata gtaaacatgg aaattgaaaa gaggattgaa aagaagaaat gatcttttcg
    59521 aatcaatccg ttaaagaggt aatccttgct atattttgca aaaagccaaa cacctaaact
    59581 gaggaatact aaggttgaac caccaccaac aaagacatct agcagtccga agctaaagaa
    59641 attagcaatc atacaaccga tggtaactcc gatgatgtac ttaggattgt aaaaagccat
    59701 aaagttcatc atttctgaaa tacgaaactg ataagcacca tagctgatgg catttagggg
    59761 cggtgtgaca gtcaaaacga cgtagatagc agcgacgatt gcaatatctg caacatcacg
    59821 aatagttaat tttttcatct tttctccttt ggcggttatc cgcgtgtaat atgcttggtg
    59881 aaagaagcta agcaccaagg gttgattcat tcaaccttac tagtatagca caatagcctg
    59941 ctttatgcta tacttaaagc atgaaaaaac ctattcaaaa attttttaac aatgaaatct
    60001 tagcctatct cttttttggc cttgcgacaa ctctagtttc gattctctca cgactagtca
    60061 tttatcaact aagtcatcag gaactccttg ctacggcctt ggcaaatatt atcggtatct
    60121 tatttgcctt tatcacaaat gatacgattg tatttaagca aaaaaagaaa aatagactta
    60181 tccgtttagt gaaattttct cttgctcgcc tttctacttt tctgttagac ttgtttttaa
    60241 cttttctctt tgtaacccaa tttcctcaca tcatagggca attcgtaact gaaaacattg
    60301 ataagataaa tgctattgaa acaataattg cacaaatatt cattattatc atcaattata
    60361 tcttgagcaa ggtctatatt tttagaaaat aatgctccat ttatgagcct tttaattgcc
    60421 ttctataatg atttaggata caatgaaaca cgaaacattg aaaggaaaac agtatgttaa
    60481 aaaatctaaa atcgttcttg cttcgaggaa atgttattga ccttgctgtc ggtgttgtca
    60541 ttgcctctgc ttttggtgct atcgttactt cacttgtaaa cgacattatc actcctctta
    60601 ttttaaatcc cgctttgaaa gctgctaaag tcgaacgtat cgctcaactt tcttggcatg
    60661 gagtcggcta tggtaacttt ttaagtgcta ttatcaattt tatctttgtg ggtaccgccc
    60721 tcttctttat tatcaagggc attgaaaaag cacagaaact gactggcata aagaaagaaa
    60781 aaactgccga aaaaaaacca accgaattgg aagtccttca agaaataaaa gctctccttg
    60841 agaaaaaata atcgattaaa aggatctagc gcaaagctaa atcctttttt ctttactctt
    60901 tgggtaactt gcctgctttt tcaagcattt ttttgataag ataaggcatc ttaatattct
    60961 cccgcccttt tttctcaatc agttttttca caaattctgg catttgtaaa tcttcagatt
    61021 cagctaaaat gtttttcgtc tcgtctgaag gaactaactc atcaaaggtc tcttcttctg
    61081 ggagaaattc cttaaactct tgattttcat tgactctaac tgtattgacc aaagcatcaa
    61141 tcaaacgaga atctgtattt ggcattggtg gacgatggta gtttacccca aattcctgac
    61201 ataaatcata acattccaca tcattgtcaa acaagacctc aatatgctca ctgatgaaac
    61261 taataggtac aaaaatataa tggtctggat gttctgtctg ttctctgaga tactccaaaa
    61321 catctggttt aatccatgga ataccaatat cactctcact ctgccaagtg ttggtatatt
    61381 gttctgaact caagcccagt ttttcagcga ctagcttgct attttcgaaa atttggtcta
    61441 tataaggatc tccaaagtcc aaggcaaaaa taggcacact atgggctgaa aagatgactt
    61501 taaagctgtc ttgctttact tcttctttta aaatcttagc aatttcatct gcccaatagt
    61561 ttaagagcgc ttcttcctga taccagtcct taatgaccaa aaattgaatt tgtttgcttt
    61621 ctaaaaattt ttcatagccc atgacagagt agaaagaata atggggctcc aaaatcaagc
    61681 aaatacactg ttcaattccg tctgcttcca tttgaccgat cacatctgga ataaagggac
    61741 tggaaaactt attagcaaag tagacactgt attcattccc cagcctagct tctaccaagg
    61801 caacctcttg acgggtaatt ttttgcagag gcgtgcctcc aattcgtaca taattatcat
    61861 agagagtctg aatctcgtgg tcttggggtc tcatcccacg acgaatattt gtgaaaaaat
    61921 cagctacacc ttcaaaggta atctcttctg gtgaaccgaa ggtcatcatt aaaattgctt
    61981 ttttcatgac tgcttccttg tgatgttttt atcaagttta ttttatcatt aattcatcga
    62041 taagtaaacg ctagcatagg gacattctca atcttctgtc ttttgttttt ctcttctttc
    62101 tatgatacaa tggaaaaaat aaattcaaaa ggagtttttt atgacttatc caaatctctt
    62161 ggaccgcttc ttaacctacg ttaaggtcaa cacgcgctct gatgaacact ctactactac
    62221 tccaagtaca cagagtcagg ttgacttcgc aacaaatgtc ctaattcctg aaatgaaacg
    62281 tgttggactg caaaatgttt actatctacc gaatggtttt gctattggaa ccttgccagc
    62341 caacgatccg tctttaacac gtaagattgg ttttatatcg cacatggata ctgctgattt
    62401 taatgctgaa ggagtcaatc cacaggtaat tgaaaactac gatggtggtg tgattgaact
    62461 agggaattct ggtttcaaac tcgatccagc tgacttcaag agtcttgaaa aatatccagg
    62521 acaaacgctc atcacaacag atggaacaag cttgctaggc gctgatgaca aatcaggaat
    62581 tgctgaaatt atgacagcca ttgaatatct aactgctcat cctgaaatta agcactgtga
    62641 gattcgtgtt ggttttggtc cagatgaaga aatcggtgtt ggtgccaata aatttgatgc
    62701 agaagatttt gatgtggatt ttgcctacac tgttgatggt ggtccactag gtgaacttca
    62761 gtacgagact ttctcagccg ctggtgctga attgcatttc caaggccgta atgtccaccc
    62821 tggtactgcc aaagggcaga tggtcaatgc ccttcagcta gcaattgatt ttcataatca
    62881 acttccagaa aatgaccgac ctgagttaac tgaaggttac caaggttttt accatctaat
    62941 ggatgtgaca ggtagtgttg aggaggcgcg tgcaagctac atcattcgtg attttgaaaa
    63001 agatgccttt gaagcgcgta aagcatccat gcaatctatc gctgataaga tgaatgaaga
    63061 acttgggagc gaccgtgtca ctctcaactt gacagaccag tactacaata tgaaagaagt
    63121 cattgaaaaa gatatgactc caattaccat tgctaaagcc gttatggaag atctaggtat
    63181 cacgcctatt atcgaaccaa tccggggtgg aacagacggc tctaagattt cctttatggg
    63241 aatcccaact ccgaatatct ttgcaggtgg cgaaaatatg cacggacgtt ttgaatacgt
    63301 tagccttcag actatggaac gtgcagttga taccatcatt ggcatcgtag cttataaagg
    63361 ctaaaaagac gaggtagctc agctacttcg cctttctttt tattctactg gtttttcttg
    63421 atttccagta gttgtagaag attctgttgt tttattttct gaagttgatt cagcaggttt
    63481 agaatctctt gtattgcttg gtttgttttc gtcgctagca gtttcaatgt tagattctgc
    63541 agttgcgttt ggttggttct cagcactggt gttatcacca tttgcttcag catttcttgc
    63601 tggacttgtt tcttcacttg cgctagcttt tgactggatt tgatgattca aaactagaat
    63661 agcttttgtc gattcaagta aagctgtttt gtctttacta ttagcagaaa gttgatctaa
    63721 taatgcatcc accttatcaa aagtccgcat cagatccatt attactttct aaataaaagt
    63781 gaagcgacat gagaatatcg tagagttttt gatagagtac aagtgtctga ggatcttgct
    63841 cagcattttc cttttcttgt tgaagggcgc tagcgatacg agtcaagaca tcttttacct
    63901 gactgtttac ttcatccaag tctgcatcag ccttgtttgt ggcagctttt agattttcta
    63961 cttcttctgc caaagattgt ctgattcctt cttcatggat tcgttccaag agttgatttg
    64021 ccttgctcaa aagactttct acttcttcct tgctatctgt cgcagattat tggttgctat
    64081 ctaccatgta ctcctaaaac aggagagtta taatccaaga ttacaaggcc ttacagaaat
    64141 aagaaatcca gataagacaa tgttcgtcca agacgctatt cgcttcgcac agcagcacgg
    64201 attcaatatg ctttaatttt aaagtttagg tgtcaagacc tctttttagt gtgcccaaaa
    64261 tttagagaag taatcaatca actaactttt atttttttca aactttcagt aaactgacct
    64321 aaagctaact caatctgtct ttgttcgata ggcttgtctt tgtagatgct tctgctatca
    64381 gctagaagtt gatctacttt tgccaagact gccttctcat caaaagttcc aggttgatag
    64441 ttggattgca gggatggaat cttgtttttc aaagccgctt catatccctt agtttgaacc
    64501 ttgatgtagt gattgtggtc gccacgagga atcacaaaac cttctgaatc ttcacttata
    64561 attcgattgg catcaaaacc atgaccatct tcttcctcat ggtggacatg tagtgacgga
    64621 ttacttaata cagaactaga agaacttcct acctcttccg tgttagagtg tgatggggga
    64681 ttgttaagag atgacttagg aatatagtga tagtgacccc atgtcttact atataagcat
    64741 cacctgtatc tctgacaata tcattagggt taaagacata accatcatct gctgcagaaa
    64801 caccattatt cggtgtcacc gacaaagatt gactgagagc tgtagtattc tctgataatt
    64861 atacttttgc agctgctaat tcacctgccg acaagtcact ctcaggaatg aaatgatagt
    64921 gaccaccatg tggtactata gtagattgaa atagaatatg agcaaattga taaggggatt
    64981 ttaaagtaat ttctaacaat gatttagaaa ctatgatgtg ctattctaaa ttcaactcac
    65041 tatatataac catcatcggt agtataacgt ccctgtaatt ttactacaga tacttctgca
    65101 ctagctcctt tatcgtcttt accatgttct tgtttttggc gattgatttc atcttttatt
    65161 cgtacatttt ctgcatgagc ttgatcttta aggtaaacat aatactttcc atctacctta
    65221 ataatatatc ctcccttaac ctaactgacg atatcttgat ctttcggctg atagttgggg
    65281 gctttcatta atagctcttc actaaagagc gcatccaaag gaactttacc attatagcag
    65341 tgataatgat cgccatgaga agttacataa ccttgatctg taatcttaat aacaatttgt
    65401 tttgcttgaa ttccttcttt ttgactaacc tagtctggag tcaaattttc agtcttctta
    65461 gtgtctttat tactgtttac atatgaaaca cgatttttat ctgtattggc ctgttagcta
    65521 tgttggttca gagcataaac acacagactt aaggaaagga taacaacaga tccagctgct
    65581 atatatttct ttttaaattt cataattacc tcatttctat aattatttat atgatgtctt
    65641 cattattaaa tgattaaata aattaattaa ccaattaatt aactagtaaa tattccacct
    65701 ctttttaagt tgtatgtcaa gaaattttat atattaataa taaaatgaaa ttctcccaaa
    65761 gtcagagttt tatttctaac ttttgagaga acttcatttt tgattcagac tttttctact
    65821 gctattcctt acgctatgag atcagataaa ttctttttta tcacttctcc acttggcaat
    65881 cttaattcaa tcgttccatc catattgaat ataacactat ctaaacctaa tccgtaacta
    65941 gctgtaaatt tttctaattt ttcttgtaca ggatctactg ctggagcttc ctctaatgct
    66001 ggatctaaca tagggtcact ccccacattc ccttctggat tcaacattcc attatccgtt
    66061 gagttttctg gttttacagg tttttcgttt ggtgcctctg gtaaagaatc tgctggttta
    66121 ttttctgttg gttggttctc aactgttcca gtagatactt ttccattttc agatggttta
    66181 ttttcaccat ttccttgagg tgcttctcct gtaaaatctg ccatattctt tttaatgact
    66241 tctcccgatg gtaaatataa ttcaattgtt ccgtccatat taaacaagac attttctagc
    66301 ttcatcccat aactttcagc aaattttgct actttttctt gtacaggatc cactgtagga
    66361 acttcttcta acgttgaatt actagtacta ttcccagttt cagaaagttt ttctttttct
    66421 accttctcac tagtctttgg ttcttctacc ttttcatcaa gttttgagtt ttcttgtgct
    66481 ttattccttt taaattgtgg tagaatactt ggtttatcag tttgattttc tttttccaag
    66541 ataggtactt ccacaatata agtcgattga ttgtccaaat aagcatttgc catgaaggtt
    66601 acaggaattt tatttccggc cgttctggtt gttccttggt ttaatttcgg aatcggtaat
    66661 ttaatttcac caactttata gttattttct aaataagcat ttccatgaaa ttcatcaaac
    66721 actctgacta aagcatcagt tcctttaggc actgcaaatt gagggttcac tcttaaataa
    66781 gtatcccctg catggaaagg atagaaaatc gtttgactgg ccattttgta agctaaagag
    66841 gttggaactg taaatgtacc atcataactt acttctggat aatcttttga agcgatagta
    66901 tacttaaatg tttgtcctgg taaataaggt tgatctaatt caaagtttgc aatattccct
    66961 actccttctc caaatacttt accagatact ttctccaata cttttccatc tggtgttatt
    67021 aattttacta gcatattgat acctaatttt ttctccaatt caggcggaaa actaaaagaa
    67081 acgcgttttt gaccattggc tagagtaaag ttttgattat taaacgtact attttttaac
    67141 aaattaacaa cattcgttaa ttcttctcca gtataaactt tattcccttc ttttttagca
    67201 actccttctt cgggtttaaa cagttcatag ttactgtgag aatgaccaat tccaaccggt
    67261 ttatgttcat caatcggatc tgcatgatgg tgatctccat gcggataaat aatcgcattt
    67321 ttttctttat tcacgacaat actttcacgt ttgacaccat attgtttcat aatgccagca
    67381 attttttctt cgattttttt atctaaatct ttcatttctt tggcattact tggataatcc
    67441 tgttcatgag atgacaaaga atctaatcca ttatgactag ttttaacttc ctctaaatgt
    67501 ttttgcgcag ccttaatttg ctcttctgtc aagtccttct tgaagaaata atgattgtgg
    67561 tctccgtgac tcatgacaaa acctgattca tcttcagcga taatacgatt agcatcaaat
    67621 ccgtatccat cttcttcatg tttctcatgt gaagttcctg gattgattgg aagagatgga
    67681 gaaggtgttg ctagactatt gtttggaaga gtcggttgcc caatttgatt tgattttgga
    67741 atgtaatgga aatgatcacc atgtcttaca atataagctg tagccgtttc ttcaacgata
    67801 tcttttggat taaaaatata accatcagat gctgaagaga gctccttact tgtcgttaaa
    67861 gaagaaggat tgcttgaaag actgcctaga ctagacacta cttcattagg ttttgcattt
    67921 gtagaaactg tagaaccagt tccactgata ggcaccattc tggcaatctt ttcttctaag
    67981 gcagaaagct tgctgtaagg aataaagtgg taatggtcgc catgcggaat cgcaactcca
    68041 tttggtgtac gactgataat cttagcaggg tcaaagacca ggccatctga ttcactgtaa
    68101 cgttgggcgc taggtgaatc atagagttcc ttcaaaagac tctggagatt ttcagattta
    68161 tttgctggct tgctagttga tccttttgct acagattgcg tgttattgtc actagctgtt
    68221 gaagaatagc ttaactgact cggttgcata ttttttccag ccagatgtgc tttagctgct
    68281 gctaattcac tagcagataa atcgcttttg ggaatgtagt gatagtgacc tccatgagga
    68341 acgatataag cattacccgt atcttcgata atatcagcta gattaaagac ataaccatca
    68401 tttgtcgtat atcgtccctg agaccttgct acagcaacat tagagttaac cttctcatta
    68461 tctttgacat gttcttgttt ttgacgattg atttcatctt tagttcgaac attatcagca
    68521 tgagctgcat ctttcaggta gacataatat tttccatcga ccttgatgat ataaccaccc
    68581 ttgacttcat tgacaatatc agcgtcttta agttgatagt ttggatcctt catcaagagt
    68641 tcttcactaa agagggcatc ataaggaact ttcccattat agtaatgata gtggtcaccg
    68701 tgtgacgtta catagccctg atctgtaatt ttgattacaa tttgctcagc ctgaattcct
    68761 tctttctggc taacctggtc tggtgtcaag ttttcacttt tctgacttga ctggctgcca
    68821 tccacataag agacacgatt attgtcctta ttttcctgcg aacgatgctg gtttagtgca
    68881 taggcacata gactcaagga tacgataaca gctgatccag ctgctatata ttttttacta
    68941 aatttcataa atccctcatt tcaataaatg atgaagtttt ttctcaactt cttttacttt
    69001 attaaatagt tttctaaacc ggttatttaa ccatttaatt aaccagtaaa tagtttacta
    69061 tttaaaatta cttttgtcaa gtttctgtta cgtttttcta aaaaagagaa gtaacacgaa
    69121 aggttacttc tccataaaat atgctccatt cattttacta ctgtatcgga gccggttgac
    69181 ttttttttaa caaagccaag agactatcta cttctgctga aatagtgtta ttatctttcg
    69241 ttccgagaag aagactactt tttagaccag tcaatgtctc catagcattt tgtctaatac
    69301 tagaatctgt tactttttct agcaaggcct ccgcctctgc tatcttagcg ttaatcacag
    69361 aatgctctac ttgaggaatt tcagtctcat ctgtagtatc ttcagcttct tcctctgtct
    69421 cttccgtatc agtgcttggt ttataaagat tatctgctga aggatttaaa ccagcgtgat
    69481 tctctttttc atcagattca gggtgagttg gctcacttac ttcatcatgt cccttatctt
    69541 catcaggttt actgtcttgg tctgccttat ttttacgaac atggtcgcta gcgttaccaa
    69601 aaccattatc tgaatgcgga cgttcgtttg gatgttcgac atagtacttg acagtcgcca
    69661 aaagatcctc aagagtatac cccttaggtg cctcataaag gccttcgtca aaccactcaa
    69721 atttgatgtt atggtaatgg tcataatgag gtatgattaa actaccgttt ttgacttcta
    69781 cagtatattg aagattgtaa ggcatacgat caagtggcac cttcttagct gctttcacgc
    69841 ggttgtagat agcttctgct ccttttgcct cagtatttcc tgaatcctga tggtctgtcg
    69901 aaggaggggt caaacctttc tctttagcat aagcctgggc tgccgctctc tcagcttcag
    69961 acaaactatc ttttttaatc cagtggctat gggtcatatg tggagttaca taggcatccc
    70021 cctcatcact ggttatatca cgaggatcaa agatataacc gtcttctgtt gtgtacttgc
    70081 ctgccaactt ggctacttga atctcat
//
LOCUS       DAVHKZ010000004        65785 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000004 DAVHKZ010000000
VERSION     DAVHKZ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 65785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65785
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.004"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..275)
                     /locus_tag="VVO74_000387"
     CDS             complement(<1..275)
                     /locus_tag="VVO74_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HEU5694476.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEEIAADFGVHESNLLRRSRWVEVT"
     gene            complement(283..724)
                     /locus_tag="VVO74_000388"
                     /pseudo
     CDS             complement(283..724)
                     /locus_tag="VVO74_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372219.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
     gene            complement(726..1763)
                     /locus_tag="VVO74_000389"
     CDS             complement(726..1763)
                     /locus_tag="VVO74_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU5694477.1"
                     /translation="MNQTINYIKELTAIASPTGFTREISDYLVHTLEKLGYQPVRTAK
                     GGVNVTIKGQNDEQQRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQTVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVTNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEEGIELPVTTHFAFSVFEE
                     VGHGANSNIPTQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(1861..3186)
                     /gene="brnQ"
                     /locus_tag="VVO74_000390"
     CDS             complement(1861..3186)
                     /gene="brnQ"
                     /locus_tag="VVO74_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU5694478.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAVAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(3357..3449)
                     /locus_tag="VVO74_000391"
     CDS             complement(3357..3449)
                     /locus_tag="VVO74_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU5694479.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(3492..3644)
                     /locus_tag="VVO74_000392"
     CDS             complement(3492..3644)
                     /locus_tag="VVO74_000392"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU5694480.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDELAALHLEGTHNLPLSQ
                     LADSYD"
     gene            complement(3804..4382)
                     /locus_tag="VVO74_000393"
     CDS             complement(3804..4382)
                     /locus_tag="VVO74_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU5694481.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFVAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     DFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMSKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(4436..5836)
                     /gene="pepV"
                     /locus_tag="VVO74_000394"
     CDS             complement(4436..5836)
                     /gene="pepV"
                     /locus_tag="VVO74_000394"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU5694482.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFDFAGPAKEYLDITGKILLNDHEGESLKIAHVDEKMGALSMNAGV
                     FRFDETCADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(5849..6454)
                     /locus_tag="VVO74_000395"
     CDS             complement(5849..6454)
                     /locus_tag="VVO74_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU5694483.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVCEKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            6625..7425
                     /locus_tag="VVO74_000396"
     CDS             6625..7425
                     /locus_tag="VVO74_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5694484.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKESSSQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTYLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSTDSPSN
                     YIVFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(7603..8436)
                     /locus_tag="VVO74_000397"
     CDS             complement(7603..8436)
                     /locus_tag="VVO74_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU5694485.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLQGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSKGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQRHNLKLLASLIEKHRYVEDVKNFFDF
                     L"
     gene            complement(8426..10270)
                     /gene="uvrC"
                     /locus_tag="VVO74_000398"
     CDS             complement(8426..10270)
                     /gene="uvrC"
                     /locus_tag="VVO74_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU5694486.1"
                     /translation="MNNLIKPKLELLPTSPGCYIYKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNEHYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKNDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVTAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(10309..11010)
                     /locus_tag="VVO74_000399"
     CDS             complement(10309..11010)
                     /locus_tag="VVO74_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEU5694487.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(11089..12321)
                     /gene="murN"
                     /locus_tag="VVO74_000400"
     CDS             complement(11089..12321)
                     /gene="murN"
                     /locus_tag="VVO74_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU5694488.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(12326..13546)
                     /gene="murM"
                     /locus_tag="VVO74_000401"
     CDS             complement(12326..13546)
                     /gene="murM"
                     /locus_tag="VVO74_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU5694489.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(13658..14437)
                     /locus_tag="VVO74_000402"
     CDS             complement(13658..14437)
                     /locus_tag="VVO74_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU5694490.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(14506..16167)
                     /locus_tag="VVO74_000403"
     CDS             complement(14506..16167)
                     /locus_tag="VVO74_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU5694491.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(16342..18564)
                     /gene="recJ"
                     /locus_tag="VVO74_000404"
     CDS             complement(16342..18564)
                     /gene="recJ"
                     /locus_tag="VVO74_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU5694492.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            18841..19599
                     /locus_tag="VVO74_000405"
     CDS             18841..19599
                     /locus_tag="VVO74_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU5694493.1"
                     /translation="MVLVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDRMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            19639..20403
                     /locus_tag="VVO74_000406"
     CDS             19639..20403
                     /locus_tag="VVO74_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU5694494.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            20416..21093
                     /locus_tag="VVO74_000407"
     CDS             20416..21093
                     /locus_tag="VVO74_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU5694495.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGATLLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            21103..21762
                     /locus_tag="VVO74_000408"
     CDS             21103..21762
                     /locus_tag="VVO74_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU5694496.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            22020..23210
                     /locus_tag="VVO74_000409"
     CDS             22020..23210
                     /locus_tag="VVO74_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU5694497.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHSLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVSSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(23531..24412)
                     /locus_tag="VVO74_000410"
     CDS             complement(23531..24412)
                     /locus_tag="VVO74_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU5694498.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(24551..25879)
                     /gene="vncS"
                     /locus_tag="VVO74_000411"
     CDS             complement(24551..25879)
                     /gene="vncS"
                     /locus_tag="VVO74_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU5694499.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(25876..26532)
                     /gene="vncR"
                     /locus_tag="VVO74_000412"
     CDS             complement(25876..26532)
                     /gene="vncR"
                     /locus_tag="VVO74_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU5694500.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(26581..26664)
                     /gene="pep27"
                     /locus_tag="VVO74_000413"
     CDS             complement(26581..26664)
                     /gene="pep27"
                     /locus_tag="VVO74_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU5694501.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(26844..28223)
                     /gene="vex3"
                     /locus_tag="VVO74_000414"
     CDS             complement(26844..28223)
                     /gene="vex3"
                     /locus_tag="VVO74_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU5694502.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(28275..28922)
                     /gene="vex2"
                     /locus_tag="VVO74_000415"
     CDS             complement(28275..28922)
                     /gene="vex2"
                     /locus_tag="VVO74_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU5694503.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(28935..30212)
                     /locus_tag="VVO74_000416"
     CDS             complement(28935..30212)
                     /locus_tag="VVO74_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5694504.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(30569..30739)
                     /locus_tag="VVO74_000417"
                     /pseudo
     CDS             complement(30569..30739)
                     /locus_tag="VVO74_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(30882..31028)
                     /locus_tag="VVO74_000418"
     CDS             complement(30882..31028)
                     /locus_tag="VVO74_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694505.1"
                     /translation="MKEANKNHPAGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVT
                     KYAR"
     gene            complement(31025..31480)
                     /locus_tag="VVO74_000419"
     CDS             complement(31025..31480)
                     /locus_tag="VVO74_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694506.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETVYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
     gene            complement(31617..32501)
                     /locus_tag="VVO74_000420"
     CDS             complement(31617..32501)
                     /locus_tag="VVO74_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU5694507.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(32505..32891)
                     /locus_tag="VVO74_000421"
     CDS             complement(32505..32891)
                     /locus_tag="VVO74_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU5694508.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(32884..34227)
                     /locus_tag="VVO74_000422"
     CDS             complement(32884..34227)
                     /locus_tag="VVO74_000422"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU5694509.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLAAQGIKLLDTKDGVRWTRD"
     gene            complement(34309..35193)
                     /locus_tag="VVO74_000423"
     CDS             complement(34309..35193)
                     /locus_tag="VVO74_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5694510.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSTNT
                     NYLYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(35205..35822)
                     /gene="cysE"
                     /locus_tag="VVO74_000424"
     CDS             complement(35205..35822)
                     /gene="cysE"
                     /locus_tag="VVO74_000424"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU5694511.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(35838..38051)
                     /gene="pnp"
                     /locus_tag="VVO74_000425"
     CDS             complement(35838..38051)
                     /gene="pnp"
                     /locus_tag="VVO74_000425"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU5694512.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDYKPKKEFTETPKDSE"
     gene            complement(38610..39476)
                     /gene="metF"
                     /locus_tag="VVO74_000426"
     CDS             complement(38610..39476)
                     /gene="metF"
                     /locus_tag="VVO74_000426"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU5694513.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(39540..41789)
                     /gene="metE"
                     /locus_tag="VVO74_000427"
     CDS             complement(39540..41789)
                     /gene="metE"
                     /locus_tag="VVO74_000427"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU5694514.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEANRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(42050..42316)
                     /locus_tag="VVO74_000428"
     CDS             complement(42050..42316)
                     /locus_tag="VVO74_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5694515.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            complement(42442..42857)
                     /locus_tag="VVO74_000429"
                     /pseudo
     CDS             complement(42442..42857)
                     /locus_tag="VVO74_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            43013..44014
                     /locus_tag="VVO74_000430"
     CDS             43013..44014
                     /locus_tag="VVO74_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU5694516.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(44082..46487)
                     /locus_tag="VVO74_000431"
     CDS             complement(44082..46487)
                     /locus_tag="VVO74_000431"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU5694517.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQINVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKKFTLTETNEAAADALSVSIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARDGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVIQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIVSLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(46564..47073)
                     /locus_tag="VVO74_000432"
     CDS             complement(46564..47073)
                     /locus_tag="VVO74_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5694518.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(47073..48119)
                     /gene="pheS"
                     /locus_tag="VVO74_000433"
     CDS             complement(47073..48119)
                     /gene="pheS"
                     /locus_tag="VVO74_000433"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU5694519.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            complement(48601..50016)
                     /locus_tag="VVO74_000434"
     CDS             complement(48601..50016)
                     /locus_tag="VVO74_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU5694520.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGSGTLNRY
                     KKMSFTWYKEVIESNGESLFK"
     gene            complement(50029..51867)
                     /locus_tag="VVO74_000435"
     CDS             complement(50029..51867)
                     /locus_tag="VVO74_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU5694521.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTLAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(51885..52724)
                     /locus_tag="VVO74_000436"
     CDS             complement(51885..52724)
                     /locus_tag="VVO74_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU5694522.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELAYLMAHIRRLTK
                     NLD"
     gene            complement(53024..54718)
                     /locus_tag="VVO74_000437"
                     /pseudo
     CDS             complement(53024..54718)
                     /locus_tag="VVO74_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(54821..55806)
                     /locus_tag="VVO74_000438"
                     /pseudo
     CDS             complement(54821..55806)
                     /locus_tag="VVO74_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
     gene            complement(55909..56070)
                     /locus_tag="VVO74_000439"
     CDS             complement(55909..56070)
                     /locus_tag="VVO74_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000270801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694523.1"
                     /translation="MKEREVLTGQRLNELEINGIRLTKFKNGEIGIEFIWIDTENPPS
                     DAIGWVAKK"
     gene            complement(56092..56847)
                     /locus_tag="VVO74_000440"
     CDS             complement(56092..56847)
                     /locus_tag="VVO74_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEU5694524.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSLEDLY"
     gene            complement(56918..59569)
                     /locus_tag="VVO74_000441"
     CDS             complement(56918..59569)
                     /locus_tag="VVO74_000441"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU5694525.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VNLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIGKA
                     TANFDKFEFGVAGHILYNFIWDEFADWYVELTKEVLYSDNEEDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELDRLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(59581..60543)
                     /locus_tag="VVO74_000442"
     CDS             complement(59581..60543)
                     /locus_tag="VVO74_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEU5694526.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDTNFAYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKLFLKLNHNTLVDIKSKLESLKLKHSRYYISK
                     ISKYDLKYNPGNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
     gene            complement(60545..61102)
                     /locus_tag="VVO74_000443"
     CDS             complement(60545..61102)
                     /locus_tag="VVO74_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5694527.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAACALIDLAFKELGLHKIELTCFGYNLQSQRVSEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            complement(61089..61538)
                     /locus_tag="VVO74_000444"
                     /pseudo
     CDS             complement(61089..61538)
                     /locus_tag="VVO74_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
     gene            complement(61951..62346)
                     /locus_tag="VVO74_000445"
     CDS             complement(61951..62346)
                     /locus_tag="VVO74_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU5694528.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(62442..62696)
                     /locus_tag="VVO74_000446"
     CDS             complement(62442..62696)
                     /locus_tag="VVO74_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU5694529.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(62706..64040)
                     /locus_tag="VVO74_000447"
     CDS             complement(62706..64040)
                     /locus_tag="VVO74_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU5694530.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(64040..64273)
                     /locus_tag="VVO74_000448"
     CDS             complement(64040..64273)
                     /locus_tag="VVO74_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU5694531.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            64304..64378
                     /locus_tag="VVO74_000449"
                     /pseudo
     CDS             64304..64378
                     /locus_tag="VVO74_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(64721..64903)
                     /locus_tag="VVO74_000450"
     CDS             complement(64721..64903)
                     /locus_tag="VVO74_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694532.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(64905..65684)
                     /locus_tag="VVO74_000451"
     CDS             complement(64905..65684)
                     /locus_tag="VVO74_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694533.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQDPTTLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
BASE COUNT        19027 a        14793 c        11973 g        19992 t
ORIGIN      
        1 gttacttcaa cccatcggct ccgacggagt aagttgcttt cgtgaacacc aaaatcagcc
       61 gcaatttctt cataagtgcg gtattctcgc acatattgaa gagtggccat aagaaggtct
      121 tctaggctta atttaggttt tcgtccacct tttgcgtgtt taagttgata agctgttttt
      181 aatacagcta gcatctcttc aaaagtcgtg cgctgaacac caacaagacg cttaaatcgt
      241 gcatcagtta gttgtttact tgcttcatca ttcatagaac tactatacca tattttgttt
      301 cgcaggaagt ctaatctcat ccggttttgc ttggcgggtt tctgcggtca ttttttcaaa
      361 agggacccac cagactggcc cacagtcctt gagaccgtgg ccattcatat cacctcttcg
      421 tctagggaaa aggtgccagt ggagatgggc atcgccattt cctagaagtt caatattcat
      481 tttctcagca gtaaagccct tggcaactgc ctcttggact aaactcattt cttctagaaa
      541 atggagtctt gtgtcctttt ctaaaatggt gcaattccgt gacatgttcc ttggctagaa
      601 agagactata gcttgcaaaa tactgatggt ctccaatcac aagatagcct gttcccaact
      661 ctttgacaaa gtagggattt tctcccttct tgatgagctc aattctctgg caaataaggc
      721 acatatcaat ctactaaatt gcttctaaga taggcatcga ccattcgttc tgttgcgacc
      781 accgagtcaa tatgagtgcg ctcataagaa tgactagact cgatacccgc accaagaagg
      841 gcatgcttga cctctgcccc tgcagacata gccgctgaag catccgaacc ataaaatgga
      901 tagatgtcca gcttaaaagg aatatcttgc tctttagcca aggcaaccaa gtgttgacgg
      961 aagtcatagt gataaggacc tgaagcatcc ttgacacaga tagatactgt gtactcatct
     1021 gtctgctggt catctcccat tgcccccata tcgacagcta gatattccac cacttgagtt
     1081 ggaatattgg aattagcacc gtggcccacc tcttcgaaaa ctgaaaaagc aaaatgagtt
     1141 gttactggca attcaattcc ctcttcctta taaacacgaa gaagattgag caaaattgct
     1201 gcgctgacct tgtcatccaa gtggcgagac ttgataaaac cagtctctgt cacaacagtt
     1261 cgcggatcga aactaataaa gtctccaacc tcaataccca aggcgcgcgt ttctttttca
     1321 ttggttactt ttgcgtccaa acgcacttcc atattgtcct gcgtacgttc tgcagttcct
     1381 gcatccttgt agacatgaca agaagtctgg tggatgagga tggtcccaga taccgtttga
     1441 cctgtgctag ccacatgaac ggtacagttt tctccttcaa tcatgttcca aggaaaacca
     1501 ccaatacgat ccaatttgag acggccatct ggtttgactg cacgaacaat agcacccagc
     1561 gtatccacat gggctgtcac atagcgttgt tgttcatcat tttgaccttt aatggtcaca
     1621 ttgacaccac ccttagctgt acgaacaggc tggtaaccaa gtttctctaa agtatggact
     1681 agatagtctg agatctcacg agtaaagccc gttggagatg caatagcggt tagttctttg
     1741 atatagttta tagtctgatt catttcttca cctctttcgc tacctattat aacacattta
     1801 tcatcggata aaaaaagaaa atcactcctg tagacttggc tacaaaagtg atttaagtga
     1861 ttattccatt tcaaaaacat cgctttcttg cttgtttggt agaaccaatg agagcaagat
     1921 tccaacaatg gctggcacca accatgggag agatgccttg gcaaaaggaa gaacgctaac
     1981 aagatttgca agaaactcaa ccttaaacga gcttcctagt acgcttgcaa tggcaataac
     2041 tgtaaccaca gcaattgtca actgcatacc tggttttgaa agggcaacaa atttgttgac
     2101 aatgacaatc ataacgatag caatcgtgat tgggtacaag ataaccagta ctggaattga
     2161 gtacttgata atcgcatcaa gacccaaatt ggcaatagca aatccaatca aggtaaaggc
     2221 tgtcgcataa accttgtagc tgatttgtgg gaagcgctca ttaaagaact cagctgttga
     2281 cacaatcaaa ccaacagtcg ttgtgaagca ggttacggta accatagctg caaggaagag
     2341 ttgagctgtt gagccaaaga tttcttgagt ggcttgtgac aagatgtaaa cacctggtgt
     2401 tccacccttc atcgcttcag ctggtactgg gaaatgattt ccaagaaaac ctaaaccgat
     2461 gtaaagagcg ctgaaggcaa gggcaacaac gataccaaca acccaaatag ttgaaatgta
     2521 ttctttctta cttgaaaatc caagttgttt caaggtttga actgcgatta cgctaaaggc
     2581 cactgaggca agggcgtcca aggtattata accttctagg aaacctgtac caaaggcaga
     2641 agcttgataa gcagctgaag cagcttgagg acttgttcca ccatatttga tagctcccag
     2701 aacgaccaag ataacaatca aaattgcaaa gactggcgtt aaaatacgtc caatgcggtc
     2761 taagattttt gatggattaa gcgaaatcaa ataggctacc gcaaaataca gaaccgtaaa
     2821 tacaatcaag ccaagtcctt tatttgcatc cgacaaaagg gggctaatcc ctacttcgta
     2881 agctgttgta gcagtacgtg gggtagcaaa gaatggaccg attgacaagt aaagaactga
     2941 gaggtaaaga gtcgcaaacc aaggcgctat cttcgttgaa atctcgtaga tatatccttt
     3001 aggatttagc gttccaataa taagggtcaa gacggcgata ccaacgcctg aaaagacaaa
     3061 acctgcgatg gcaggaagaa aatgttctcc agatagagca cctagagaag gcggaaaaat
     3121 caagttcccc gcaccaaaaa atattccaaa caggagcaaa cctgttaggg tacctttttt
     3181 agccataaaa atctccttca tatttataaa atactgacct agtataccac gattaggagt
     3241 ctgaaaaaag catcacgagg caaatattaa atgttttcaa ttttcttaaa aataagaatt
     3301 atctaaaaac aaaactctcc tacccagtcc acaccaagta ggagaaatgc aaaattttaa
     3361 agttcttcaa aggctaacat gccaccctgg acattgataa cattataacc ttgttctaac
     3421 aggaattggc aagcacgcgc cgatctcatt ccagatttgc aaataatata atgcaagcga
     3481 tctttgtcca attaatcata actatcagcc aattgactaa gcggtaggtt gtgggtacct
     3541 tctaaatgaa gagctgcaag ctcatccact tctctcacat ccactagaga aagctggtcg
     3601 ttttggtaaa gctgataaaa tgcgtcaaag gctatttctt tcattctttt tcttctaata
     3661 ctcttcgaaa atctcttcaa accacgtcag cgtcgcctta ccgtgcgtat gttaccgact
     3721 tcgtcagttt tatctgcaac ttcaaagctg tactttgagc agcctacgac tagcttccta
     3781 gtttgctctt tgattttcat tgactataaa atggttttaa ttcttttttt caaatctggc
     3841 actacttctg cctcaaacca aggatttttg gacatccaga tttgatttcg tggtgatggg
     3901 tgaactagcg gaaaataggc tggcagatag tctttatagt gtttcaccct ctccgttacc
     3961 ttcccactga ttttctcctg taaatagtag gcttgggcat attgcccaat caagagggtt
     4021 aactgaatat caggcaattc ctgtaagagc tgcggatgcc atttttctgc aaaatctgta
     4081 cgaggcggaa gatcacccga cttgccatgt cctggaaagt agaaatccat aggcaaaaca
     4141 gcaaaataac ctgaattgta aaaggtatct tcatccacac ctagccagtc ccgcaagcgg
     4201 tcaccacttt tatctttcca gtaaaggcct gcttcttgag ttttaagtcc cggagcctga
     4261 ccgatgatat tgatgcgagc agtttttggc gctacaaaga gaggctcaat gccacgctct
     4321 gtatagctgg cattctgcga atccgccatg atagcctgtt tgattctttc gatttgagac
     4381 atctactttc cctccaaaaa gaagtccaag cataagatct cagacttcta tcgttttatt
     4441 tgatcaattc gtaaatagct tcggcataaa ttgctgctgc tcggaagaga tcgtccaagg
     4501 caataaattc attggcttgg tgcatagtat caattgagtc tgggaacata gcaccatagg
     4561 caactccgcg ctctaacaag cgaccaaagg ttccaccacc gatgacttgt tcatgacctt
     4621 gtaggcctgt ttgtttttca tagacattca acaaggtttg cacaagtgga tcttccattg
     4681 gcacatagtg aggggtatga ccatgttctg atagactgac agaagcaact ggcaagtttt
     4741 ctaggattga cttgatttgt tctggacttg ttccttttgg atagcggatg ttgagggcaa
     4801 tggtattatc agcacatgtt tcatcgaagc ggaagacgcc tgcattcata gaaagggcac
     4861 ccatcttttc atccacatga gcaatcttga gactttcacc ctcatggtcg ttcaagagaa
     4921 ttttaccagt gatgtcaagg tattctttgg ctggaccagc aaagtcaaac tggctaagga
     4981 agagggctag gtaagtcgca ccattgacac ctgaagcagg catagcaccg tgggctgatt
     5041 taccaatgat cgtcaccttg tatttgccag cttcttcttg gagttctcct ctaagtttgt
     5101 gttctgcaac aaaggcatct agtttagctt gcaagtcagc caaatcacct gaaacgactg
     5161 ctgttgctga ttctggtacc atattttcac gtaaaccacc tgtaaagctg tgaagacggg
     5221 cagcacctgt attttctcct gcaaagtgga ggtattccgt gatatttcct ttttcaccat
     5281 tgatgatagg gaattcagcg tctggagaga aaccgaaatc tggtttggca agtcctacgt
     5341 gctcaaagta gtagtccata tctgcccagc ctgattcttc gtctgttcca acgatgaagc
     5401 gaactttctt agaagttgga agacccaatt ctttgatgat tttcaaacca tagtaacaag
     5461 ctgttgtagg acccttatcg tccgaagccc cgcgcgcata aaggcgacca tctttgatag
     5521 ttggtgtgta aggatctgta tcccaaccgc taccagctgg aaccacgtcc atatgggcaa
     5581 agattccgag aacttcttct ccatcaccaa actcaaaatg tcctgcatag ttatcaacat
     5641 ttttagttgg ataaccatca cggtctgcga tttcaaggaa tttttccaag gcttttactg
     5701 gaccaggtcc aaatggatgt tgggcatcag ccttgctatc atcacgttct gagttgattt
     5761 ccaaaaggct aaacaagtca gccaagaggt cttctttgcg tttttctact tctgctgtaa
     5821 aatcaattgc tatcattttt tcttcttcct atcttttttc gatgatttca tctactggca
     5881 agcggtagct tggttccaat ttgtcgtctg tgtaacccac tgtgatcaag agttctgggc
     5941 ggaaacggtc ttcgatttcc aaaacttcat taacttttga tttgtcaaaa ccaaggataa
     6001 tattggaacc aattccttgg tctgtaagag cgagaaccaa gttcatagca accaaacctg
     6061 cattgagtgc taggtagtcg ctgacttgtt gttcattgta gcgtgcaaat tcagctggca
     6121 aatttttcat gaagtattga agttgttctt ctgagaaatt gttagcacca ccaactcggg
     6181 caatcttacg agcgcgtttg gcaaggtctg tatctgtaaa tagggcaatg gttacaggtg
     6241 ctgatgatac ctgttcaaaa ttggaaccat aagctaactt tgccagttca gcatttttct
     6301 cacataccac cacaaatttc caaggctggc tgttgtgggc gcttggcgcc aaggttgcaa
     6361 tttcgatagc cgtacgcaca tcttttggat caacaggctt atcagtgaaa tgcttggtcg
     6421 catgacgttt tttatttaat tcaagaaatt tcataatcga tttccttttc taattctact
     6481 gcttccattc taccataatt tgaaagagct tgcagggatt tttcatgatt aagtttttct
     6541 atcacagaca taaaagatat atattggttt atcaggaaag tttctgataa actagcaagt
     6601 actttacatt tgaatggaga cagtatgaaa aaatttagcc tattactagc tatcctacca
     6661 tttttggttg cctgtgggaa tcaagctaca cccaaagagt ccagctctca aaagacaatc
     6721 gtccttgcta cagctggcga tgtgccacca tttgactacg aagacaaggg caatctgaca
     6781 ggcttcgata tcgaagtcct aaaagcagtg gatgaaaaac tcagcgatta cgagattcaa
     6841 ttccaaagaa ctgcttggga gagcatcttc ccaggacttg attctggtca ctatcaagca
     6901 gcagctaata atttgagtta cacaaaagag cgcgctgaaa aatacctcta ctcgcttcca
     6961 atttccaaca atcccctcgt ccttgtcagc aacaagaaaa atcctttgac ttatcttgac
     7021 cagatcgctg gtaaaacaac acaagaggat accggaactt ctaacgctca attcatcaat
     7081 aactggaatc agaaacacac tgataatccc gctacaattg atttttctgg tgaggatatt
     7141 ggtaaacgaa tcctagacct tgctaacgga gagtttgatt tcctagtttt tgacaaggta
     7201 tccgttcaaa agattatcaa ggaccgtggt ttagacctct cagtcgttga tttaccttct
     7261 acagatagcc ccagcaacta tatcgttttc tcaagtgacc aaaaagagtt taaagagaaa
     7321 tttgataaag cgctcaaaga actctatcaa gacggaaccc ttgaaaaact cagcaatacc
     7381 tatctaggtg gttcttacct cccagatcaa tctcagttac aataacactc ttcgaaaatc
     7441 tcttcaaacc acgtcagctt tatctgcaac ctcaaagctg tgctttgagc aacctacggc
     7501 tagcttccta gtttgctctt tgattttcat tgagtataag atatataaaa gcgattggac
     7561 taccaatcgt ttttagtttg cattggttat tttaggaaac tcttacaaaa aatcaaaaaa
     7621 attcttcaca tcctctacat acctatgctt ttctattaag cttgctaata gtttcagatt
     7681 gtgcctctga tagttatctt cacgacgtag ttcttcatac atttcgataa agggaagccc
     7741 cttggatttg gccaattcta actcagcctc gtaatcataa gcaactttac gaaattggat
     7801 attgagtaat tccccatctt caacctctat cacggcatac tgggcacggt gattttttaa
     7861 cgcctcccaa ttaaaatagg gcatgccaat cgaccctgga ttgatgattt gttgcccttt
     7921 actgccgtag cgaagcaact gcttgtgaac atgaccataa actgccacgt ccgtttccgc
     7981 atctagcagt tggtcaaatt tctctgtatc attctcaact agcaagtcac caccatagtt
     8041 tttgtcaggt aaattatgag agatagaaaa gcgcaatccg tcaatttctt tcttttccag
     8101 caaaggcaag cttcgtagcc agacaatcgt tgcaggatcc attcgctcca tcaaaaactg
     8161 ggtcatgcgc attgactgga tttctttcgg atattccaaa ccatattcgc catccaagac
     8221 ctcaaggaca cgatcatccc aattgcctcg aacacttgct gtgataggaa ggtcctttag
     8281 cagggcgact aagtcatttg cgcctggacc aggaagaaaa atatctccct gaagccaata
     8341 ttcactggcc ccttgatttt tagcatctgc aatcactgct tctagcgccg tcgcattgcc
     8401 atgaacatct gataaaattg cgattttatg gttcattgtg gtttccttcc gtttggtaat
     8461 ctactctttc ttctgctact tgaggcaagg cttctccctg cgggttcaac tttctttgca
     8521 cagcctctgc aacgactcta ggtaccccaa cttcgacaat ctcatccaca ctggcttcct
     8581 tgattttggt caaagacttg aaatgcttca taagattctg cttgcgttta ggtcccagac
     8641 cgtcaatccc atccaattga gatgagaaag aatttttgga gcgcagttgg cggtggaaag
     8701 tgatagcaaa gcggtgcacc tcatcttgga tgcgttggag gaggaaaaat tcctgagaat
     8761 tgcgagacaa gtccaccacc tcaagcggat ctccaaagag caattcatgg gtttggtgct
     8821 tatcattctt ttgcagccca gcaattggaa tatccaagcc cagttcctct tggatgactt
     8881 gcttagcaat attgacttga ccttgccccc catcaatcac aatcaaatct ggaggagtca
     8941 aagcctcacg ctgtactcga ccatagcgtc tgcgaatgac ttctctcata ctagcatagt
     9001 cgtccggccc aacaacggtt tttatcttgt acttacggta atctttttta cttggcctgc
     9061 cgttaacaaa gaccaccatg gctgaaacag gactggtccc catgatgttg gagttatcga
     9121 aggactcgat gcgaactgga gtcggaattt ggagcaaacg tcctagattt tcaatagctc
     9181 cttgggtctt ttcgactgat ttttctagca gattgaactt ctgctctaga ctaacacgag
     9241 cattttttat ggctagattg accagctgtt ttttctctcc acgttggggt ttgagaatct
     9301 tggtatccac caaagccttg acagcttctt cgtcaatatc ctgcggaatc agtacctcat
     9361 tgggaactag gtgagatttt tcttgataga attgtcccac ataggtcaag aaatcctcat
     9421 ctggatcatt gaagtagggg aagagattga catcgcgctc gatgagcttg ccctgacgaa
     9481 caaagaaaac ctgcacacac atccagccct tatccacata gtagccaaag acatcgcgat
     9541 tttggagatc cttagccatg acccgttgct tggttcgaag tgttccaatg gcctgaatca
     9601 ggtcacggta ttccgctgcc cgttcaaact ccatactttg tgctgttact gccattttac
     9661 tcttgagatc atcgatgatt ttgtcatcct gacctttcag aaaatcagac acctcctggg
     9721 ccatggactt gaaataggcc tcgtcattct tacagatggt gtgggccata cattggccga
     9781 tatggtagta aaaacagacc ttagagggcg ggttggtaca ttttcgaaaa gggaaaatcc
     9841 tatctagaag tcgcttgatt tcattggctg cccccacatc tggataaggg ccaaaataaa
     9901 gaccaccgtc ctttttgacc tgacgagtaa tgataagccg tggatagtgc tcattggtga
     9961 ttttgataaa aggataagac ttgtcatcct tgagcatgat attgtacttg ggcttatttt
    10021 ccttgatcag gttgatttcc agcagaagcg cctcaatatt agactccgta acaataaatt
    10081 caaaatccac aatttcagac accaaggcct ctgttttggt atcatgactt ccacggaaat
    10141 aagacctcac gcgattacgc agatttttag cctttcctac atagataatg gtgccgtttt
    10201 tatccttgta aatgtagcaa ccagggctgg tcggcaagag ctctagtttt ggtttaatca
    10261 agttgttcat agttccatta tagcaaaaaa gtagggaaag atagtaccct actcattagt
    10321 ctcatatatt tttcggaggt ttgcaacatc ctcttcctgg ataccataaa aggaacctgc
    10381 tggttgcatg acagacttct catctgtatg gtccaagcca atcgcatgac ctaactcatg
    10441 ttctgccgta tggacaaggc gttcatagga atagccatag tatggattgg acaaataata
    10501 atgattcaac cgcaccgtta cggacaagaa ttgccctgtt aagagattag tttgactttc
    10561 cgcctctcct gccacaggag tgcctccgtc gttcatctcc gtagccgtaa tatccgcctt
    10621 actagactca gtcacgagtt caaagttaaa agcaccagtt tgattccagt tctggattgc
    10681 ttctaaataa gcctcttgaa agcgtgaatc catctgcgga tccaggtaaa tacgagcaga
    10741 ggcctgtggc caccttcctt cagaatgctg gtgactatct gtctggctta acttaggcag
    10801 ttgccctgtt ttctcccatt ggtcaatact ttgttgacca atttttactg accgttctgc
    10861 ttgctttagc gctccttgaa aatccccgtt cagataccag agaagtccga aagcaagcac
    10921 acataagagc acaactatcc aaaccagacg ccaaaacaaa cgccacacaa aagaaaagaa
    10981 agcccctatc aaacgaaaaa gccagcgcat gtctctccac ctttctagca aataaaaatt
    11041 attttactaa aagaagctaa aagaaatcta aatactgact ttttcatctt aacgtcctac
    11101 tatttttttg agtaactgga tagctttgta ttttaaagga gatggatggt aacggaaagt
    11161 acctgctttg cgtacaatat agccattaaa attctgttta aaacgcaaaa caccatcact
    11221 tccatcaaaa atcccttgaa tgcctaggaa gttgtattta ggtattccac gttttatgct
    11281 ttccaacata acatattttt gaagcagtgc aggggcatag aacttattaa actcagtgta
    11341 ggaaccacta aagagataag tcgtttcctg aggcatataa acaaataaac tcccagctaa
    11401 aacaatatct tcttctccat atttttcaat caagtctcgc gcttctgctt ttcgaacttc
    11461 aaacgtttca aattgactag aatattctct cagttgattt tgttttttct cagaatgagg
    11521 atttttactc aaatcaagtc gcaacttgtc caagttttct tctagtttat tttgttcacc
    11581 ttgcaatttg ctcatatagt ccgaaaaatt taagcttgct atgagaaact ccgcttgttc
    11641 tccaaaagta tcataaaaat gctcataata ttctaaactt ttatcactat attctctacg
    11701 ttcagaggtt tcttttgtta tattcttaaa aatcgatagt tcttcacgtt ttaacttttt
    11761 caatcgaatg ccaaaggttt cagccttttt caccaagggt ttaccctttt tgctaaaact
    11821 tttaagcaaa ctcttttcag ttaattcagt taaatcttta tagtataacc aatctggttc
    11881 tccacctggg taacctgttg ttaagccatc aaattgataa cctaaatcag tcaaaccttg
    11941 aataatactt tttttctcag catctattgg attaccttgg ctatcaaaag tttgataagt
    12001 ttcataaggt tttacaagca actctaatac accattttgc ttggcatatt cttttaactc
    12061 tgcataaaaa actggaagag catcttgttg ggtataaatc ggccccgaat tgagttccat
    12121 atgcagacca cccagcatgg gcaagctata aaccagagct gcaacttgaa tttctccttc
    12181 ttgtttcaaa gcaagataaa caattcgagc ccctcttttt tctagcaaat cccccatctg
    12241 gacagattgc ataaaggaac gagaagaaac ctgatcagaa taagtctgaa actcttcttt
    12301 cgtgagtgtt gttagtgcca tatacttact ttctatgttt ttttcttaat gttttacgga
    12361 aatcaagagc aagtcttaac agaggataga gaggatgagt gggcattgta aattcaccca
    12421 agtattcttc aatcgttgga ttaaattttt ccttaaaatg ataaagtcca ccattgagag
    12481 agttttcaac accacctaaa ttttgccaga ccatacctcg ctcaaaggca tagcgagccg
    12541 tttcatacca tgttaaaatt ggtgcattgt aacgtttaaa atcatcatcc ataccagcat
    12601 atatattgac agaggtagta ccaaattcca aactcaaagt agccgctaaa ggaactctcg
    12661 cttgacctac atctatatat tcctgcaaga aggtcaattc ctctaacaaa cgttcttttt
    12721 ccttcttctg cgcttctact tttgaagttc gagtcgactc agtaaaggtc tcttccaagg
    12781 ctctattttt cgctaactgt tcttctaatt cttgcgaacg tttagaaaca tccaaggtgg
    12841 ccaaggtgat ataggccttg tccttaaaat tatctaacaa ttttttataa taggcttcat
    12901 tcctcaaatg aatctctttt cgcttctcag tttttttcat caactccgaa aatgaatcta
    12961 atagttccag tccaccatat tgaatctcaa gccctttgtt tcgtgctgtt cgaatagcct
    13021 gttttgttga cttggaaagt ttatcttctt caaaattttc cttgtatatt ttcgcctgaa
    13081 tacgaggttg aatggtgtct cccatttcct ccgtttttcc tgaccacctt actcccattt
    13141 gttgcaaact atcaataata gccagatttt caggaaattc tgtcttttcc tgattgatta
    13201 aactttgaga taggcaaata cttgggtcaa aagtcacaaa aaccgctctc ttactgcgag
    13261 cataggactt aatagactga atggcaaaat tcaagagttc tttatcccca taatccaata
    13321 taggtcctct tgggatgtaa aacattttat agcctagcgg aagagttcta atcaaaatac
    13381 tagctgtcgc cagtaatttt tcttccctgt aaacaccaaa cttctcatgt tgccaattag
    13441 acttaacttc ctcccaagca ctactttgta atacattggc taattcatgt tctttgacaa
    13501 actgatcata ttctaatgtg ggaatgccaa tttgataacg gtacatttcc tactctcttt
    13561 cctccagtat tttattacta ttctactact ttcgtttgaa aagtctagtg aaaacatatt
    13621 ttattttagt tctactcccc ctatgctgaa gttcaaacta agtcagtctc tcttctaatt
    13681 tgaaatcaat tggtagggtt gttaaaaaaa cttccaattg tttttcccag tagtaccact
    13741 cgtgagttcc agcactatgg ctataggtca catcaaaacc tagttttttg agatttttca
    13801 ctgcgagatt attggcttcg tacaagaaat cctgttcgcc acaccacgcc caaagtttgg
    13861 tctttttatc cgatttttta gccagacttt caagagaata gggactagtt gtccagtctc
    13921 taatctctcc aaaaacacct ctccagtagg ctggacttcc cagattttga ctttcaggag
    13981 aaaagttttg aaagctgagg gcacctgaaa aactagctgc atgagaaaaa cgatttgtcg
    14041 taagagccag tttgaagcag ccgtagcctc ccatagaaag accagcgata aaggtctttt
    14101 cacgcttgct agtcatatta gggaagaagc gtttcagaac ctgcggcaat tcctctgcta
    14161 gagccgtgta gtagtcaaaa ccatactggg tatcggtgta ccaaccattg ctggtattgg
    14221 gcataacaac gatgagatta gttcctcgaa gcaagcgttc tacattggtc cgcttaagcc
    14281 aactattatg atttccagac atcccgtgca aaaggtacaa gacgggaata tcttcacact
    14341 ctggttcttc cactcgattg gcatcagggt agaggacatt caccccccac tccatatcca
    14401 atacttgtga gtaatactcg attttcatta ctgccatgat tttctccttc tatttttcta
    14461 taagaaaaag ccgaaactcg actttctctc tgtttatttc aacgattatt ttgcttccat
    14521 gactactggt aaaatagctg gacgacgctt ggtttggtca aagagatact tggtcaaatt
    14581 atctcgaacc ttccctttaa gatctgccca gtcaaagtca tctccttgaa gataatcttc
    14641 taccgtttgg ttaatcaatt ctgaactttc acggagaata tcgcgactct tcttgagata
    14701 aacaaatcca cgcgtgtgaa cacgagccct agccacaatt ttcttctcac gacggttgac
    14761 tgtaatagcc acgatgaaaa ttccatcctc tgacaagacc ttacggtcac gaagaacaac
    14821 atttccaaca tcaccaatgg cattcccatc aatcaagata tctcctgctg aaaccgatcc
    14881 agctggaaca aagtctccat tctcgtaagc catggtcgtc ccctttttag gaatgaaaat
    14941 gcgttctggc aacatcccaa ctgccatggc agccttagcg tgagcatcca actcacgata
    15001 ctccccttgg acagggaaga ggtacttagg ttgcaaaaga ttgatcatca gctgcaaatc
    15061 acgcacattt ccgtgccctg atacatgtaa actttgggta atcaatttga caaccccacc
    15121 tgcctgataa atcatatttt ccacacgcgc aacaaaggct tctttagcaa tagacggagc
    15181 cgtagcaata tagaccaggt ccccatcctt gatttctaca taacgatggc gaccaatcga
    15241 catcttacga agtccattga taggttcacc catacgacct gtctcaagaa taatcaactc
    15301 atggtcttca aagcgagaca tatctttagg cttaatcaag agaatttcgt tggctaaaga
    15361 caacttctta agacgaatcg ctgtgcggac gatattttca atatcaaatc ctgtcaagac
    15421 gatacgtcga cctgttttat ccgcagcgtc aaaaatctgc tgaatacgag aaagattact
    15481 ggaaacagct gcaacgatga tacgaccttc ccagtcagca atagtttggg taatttcatc
    15541 cctaacttca ctttcactag ccacctgaat attgctgtct gcattggccg aatcactgag
    15601 gagagccagg acgccgtcac gaccaatctc tgccaaacga gcaaaatcag ttgcataaga
    15661 ttcactagcc gtttggtcaa atttgaagtc acctgtataa acgatgcttc cttccgatgt
    15721 cttcaagaca attcccagac tctctggaac ggagtaagtc gtagggaaga aggaaaccac
    15781 tgtcccacca aaatcaatct ccgtattctc atcaatgaca tggaaatcat taaatttctt
    15841 aacggcatca tttcctttga caaagagctt tgccaactca atggtcaact cagacccaaa
    15901 tacaggaact ttagcctctg ccaagagata aggtagagca ccaatggcat ccgcatgccc
    15961 gtgggtcaag aaaaccccag caatacggtc gctattttca aaaaggtaat ccatgtttgg
    16021 aatcaccaca tcgaccccta attgttcatt ttcaggatat tttaacccta cattcaaaac
    16081 aaaaatggac tctccaattt cagcaatgta catatttttt ccattctcac gcacaccacc
    16141 aagtgttgtt aaactgatat tactcatttt tcctccaaaa tcttagttta tcttgattat
    16201 agggcaattc taccctctta ttctaaaagt tctgatactt tcagccgaat cttttcctac
    16261 cattatacca tttttttgat gattttcaaa atgaaggtct gttttcaaaa aagagttgat
    16321 ttcccaactc tttcctaact tctactcttt ttccatcaaa aaatcataaa tttcttgcac
    16381 cgtacccagc gccatcattt cttggtcttt aacggtttgt ttgagatttt ggtaaatttg
    16441 actttctcct atctcccgct ttggcgcctc tttattgact gtcatcacac catcttttat
    16501 cgtcacaaag cctagttctt caaatacttg aatcatcttg accagcaaga tttgttgaat
    16561 attaagatat gcagccaaat ctttcagctt gtagcgaata tcaaactctg ggaactggta
    16621 aatagtcttg tacaatttag caaactgatc tctagtccca taacctgtca gataataggt
    16681 cttgtcaata tcatttttga aatagacagc agagaaatgc tgttcctgaa aaatggtctt
    16741 cagctgagta atatcctctg gaatgttttt tacgacaaca gcttcactag ccgcaagatt
    16801 tggcagttct ccaggaaaat ccaagactgg aacaccttct ggcaagactg cattttttcc
    16861 acgaatgtta aaaagttgaa caccttccac tcgcgcatcc accatcatca actggagggc
    16921 agtttggcca ttccattggt tgacagacaa tttaaccgct aactctagat tcttggtttg
    16981 agaaaactct gtcgcccatc tgccttgacc aaaggctacc acttcaaaac tcgcctcacc
    17041 cttggaaatt ttcagcttta gatgggcatt acctgccccc atagtacgag cactttcgac
    17101 ctgaaaattc ttgatataaa aaataggttt ctgattatcc attccaaaag gagctaaacg
    17161 ttcaaaactt ttgaccgttt ccaagctaag tgcctccaaa tccaactctt catctaggtt
    17221 taacttattc ttgccaccag catctgcacc tttttcacga acataatctt ccaaaacctg
    17281 agataaatct gagagttgct caacttccag cgtcataccc gctgcacctg catgacctcc
    17341 aaaggcgatg aagaggtctc gatggggatc cagagcttca aaaatatcga ccgcttccac
    17401 actacgagca ctgcccttgg cacgaccgtc ttctatatta agaacaatga ctgtctgtcc
    17461 caattcttcc aataaacgac cagccacgat tcctagaacc ccaggattcc agccttcctt
    17521 ggccaagacc tgaaccttct tctcaggatc caccatggtc ttggcttctt catagataga
    17581 ctgaacgatt tccttgcgct cttcgttttt ctggtgaatc ataagggcaa tctcatgcgc
    17641 ttcctcatca tcaaatccag tcaacaaatc aatggcagga ttgggatcat ccaagcgacc
    17701 caaggcattc aaacgaggag caatctggaa accaaccgtt tcttctgtta cttcgttggc
    17761 agcaatccca gccatgtcca gcatttcttg cagaccaatg cgctgggtat gacccaacat
    17821 ttccagacca tattgaacta agatacgatt ttcatccgtc agactcacca tatctgcaat
    17881 agttccaata gcgaccaaat caagcaattc cacttgcact tcttctaaca gggcacaagc
    17941 caacttgaaa gcaactccac aaccagccaa atatttaaaa ggataatccg catctggatg
    18001 ttcaggatgg acaatagcat aagcatctgg cagggtttca ggcatggaat gatggtctgt
    18061 cacaatgaca tctactccca tagactgagc caatgcaata gcctcatgac cagcaacccc
    18121 attgtccacc gtcacaatca aggaaattcc ttcttgctcg ataaagtatt tataaacact
    18181 agcattaggg ccatagccat cggtaaaacg atttggcagg taaactcggc actcagcacc
    18241 aagttgttcc aaactttcct tcacaataga agccgaagtc atgccatccg catcatagtc
    18301 tccataaacg agaatatttt ccccttcttc aatagcctga cgaatccgct ccactgcctt
    18361 gtccatatca tggagcagat aagcatcatg taagtcctcc aaggaaggtt ctaaaaactt
    18421 cttcagactt tcttggtcct gaatccctct ctcaaacaat aaccgagcca cctcaggacc
    18481 cagtccagcc ttcttggcta tctttgtaaa atccgcatct tctacctgca gggcaaactg
    18541 ccattcataa gtaggtgtta tcaaaaagac atccactctt tctaagaatt ctattgcttc
    18601 attataacat gatttagacg ttttctctat ccagattgct tttttataac attttatagt
    18661 atattgaaac tagaatagta cacctctact tctaaaatat tgttagaaat cgatttgact
    18721 gtcccgatcg atttttcctg ttcttatttc actatagtga attttttcag atatgatttg
    18781 acaagaacat tcttttattg cagaatcgtg ttataaaatc taacataaag gagttctctc
    18841 atggttttag tagaatttaa aaacgtcgaa aaatattacg gagactacca cgcactccgc
    18901 aacatcaatc tccgttttga aaaaggacaa gttgttgtcc tgcttggacc ttctggctct
    18961 gggaagtcca ctcttatccg tacgatcaat ggtttagagg ctgttgacaa aggaagtctc
    19021 ctagtcaatg ggcaccaagt tgctggtgcc agccagaaag atttggtacc tcttcgcaag
    19081 gaagtcggca tggtttttca acattttaac ctttatccac acaaaacagt gttagaaaac
    19141 gtgacacttg cgcccattaa agttctagga attgataaaa aagaagctga aaaaaccgcc
    19201 aaaaaatatc tggaatttgt aaatatgtgg gacaagaaag attcctatcc cgccatgcta
    19261 tctggtggac aaaaacagcg gatcgccatc gctcgtggtc ttgctatgca tccggaactc
    19321 ctcctctttg atgaaccaac atctgctctt gatcctgaga ctatcggaga tgttctagca
    19381 gttatgcaga aactggcgcg tgataggatg aacatgatca tcgttaccca cgaaatgggc
    19441 tttgctcgag aggttgcgga ccgcattatc tttatggccg acggagaagt tttagtagat
    19501 acgacagatg tcgataactt ttttgacaat ccaagcgaac ctcgtgccca acaattcctc
    19561 agcaaaatta tcaaccacga aagtgacaaa gtcaaataag gaggcgccta tgaaaaaaaa
    19621 ttctttttat cagcattatt gattagcctt ttcggccttg ctgctgccaa accagtccag
    19681 gctgatacaa gtatcgcaga cattcaaaaa agaggcgaac tggttgtcgg tgtcaaacaa
    19741 gacgttccca attttggtta caaagatccc aagaccggta cttattctgg tatcgaaacc
    19801 gacttggcca agatggtagc tgatgaactc aaggtcaaga ttcgctatgt gccggttaca
    19861 gcacaaaccc gcggccccct tctagacaat gaacaggtcg atatggatat cgcgaccttt
    19921 accatcacgg acgaacgcaa aaaactctac aactttacca gtccctacta cacagacgct
    19981 tctggatttt tggtcaataa atctgccaaa atcaaaaaga ttgaggacct aaacggcaaa
    20041 accatcggag tcgcccaagg ttctatcacc caacgcctaa ttactgaact gggtaaaaag
    20101 aaaggtctga agtttaaatt cgtcgaactt ggttcctacc cagaattgat tacttccctg
    20161 cacgctcatc gtatcgatgc cttttccgtt gaccgctcta ttctatctgg ctacactaat
    20221 aaacggacag cactactaga tgatagtttc aagccatctg actacggtat tgttaccaag
    20281 aaatcaaata cagagctcaa cgactatctt gataacttgg ttactaaatg gagcaaggat
    20341 ggtagtttgc agaaacttta tgaccgttac aagctcaaac catctagtca taccgcagat
    20401 taaggaggat accctatgac agatttatca tcttggacag cctattttca ggattttgga
    20461 caatttttca atggtttcct ctttactctt gccctagcga ttggatcctt tatcctcgcc
    20521 atggtcttag gaatcttctt tggtgccatg tcaaccagta aacgtccaat tttacgcatt
    20581 ttagctcgca tctttgtgga attttaccaa aatactcctc tcttggtgca gtttgttatt
    20641 gttttttatg gcctacctct tatcagtgac catatcatca tgattccaat ttattggaca
    20701 gccgttctct gcgtgggact ctatcacggc gcttatatcg ctgaggttat tcgttcaggg
    20761 attcagtcta ttcctagtgg tcagatggag gccgccttgt cgcaaggttt tacctatatc
    20821 agtgccatgc gcttgattac cttgcctcag accttccgca tcattctccc tccattgacc
    20881 aaccaaattg ttaacctcat caagaacacc tctactgtag ctatcatctc tggagtagac
    20941 ttgatgtttg tgactaagtc ttggtcggct ctcaacggaa actatatccc agccttttta
    21001 ggtgctactc ttctctactt tgccctatgc ttccctgttg cccagtttgg tcgcaagatg
    21061 gagcaagcca acaaaaaagc ctattcactt taggaggtta ctatggaatc tattttagaa
    21121 gttttaaccc cagataacct agtctttatc tttaaaggat ttggcttgac cctctatatt
    21181 tctctgattg ccatcatcct ctctactatc atcggtacgg tgctagctgt catgagaaat
    21241 ggcaaaaatc ctgtcttgcg aatcatctcc agcatttata tcgaatttgt gcgcaacgtt
    21301 cccaaccttc tctggatttt tactatcttt ttggtgttca aaatgaaatc cacaccagca
    21361 ggtattacag cctttactct ctttacatca gcagccttgg ctgagattat tcgaggcggt
    21421 ctcaatgccg tagacaaggg acaatacgaa gcaggaatgt cacaaggctt cacctcagcc
    21481 caaatcctct actacatcat tctcccacaa gccatccgca aaatgctacc agccatcatt
    21541 tctcagtttg ttaccgtgat taaggatacc agcctcctct actctgttat cgccctacaa
    21601 gaactctttg gagccagcca aattctcatg ggccgttatt tcgaaccaga gcaggtcttc
    21661 agtctttgca tcctgattgc cctcatctac ttcagcttta acctagcaat ttctagcctg
    21721 tctcatatgc tagccaaacg ttggcaacaa gctgcagaat aatactcttc gaaaatctct
    21781 tcaaaccacg ttagctctat ctgcaacctc aaaacagtgt tttgagcaac ttgcggctag
    21841 cttcctagtt tgctctttga ttttcattga gtataaacag ccactctcca gttcaattgg
    21901 agagtttttt gatgagagta gatatttata gacctcaatt tgacaccata cattttctat
    21961 gataaaatgt aacaaattta tttacaacaa atcgaaatct aaatgaaatg gaattttcta
    22021 tgaaatcagt caaaggacta ctctttatca tagctagttt tatcttgact cttttgactt
    22081 ggatgaacac ttctccccaa ttcatgattc caggactagc tttaacaagc ctatctctga
    22141 cttttatcct agccactcgt ctcccactac tagaaagctg gtttcacagt ttggagaagg
    22201 tctacaccgt ccacaaattc acagcctttc tctcaatcat cctactaatc tttcataact
    22261 ttagtatggg cggtttgtgg ggctctcgct tagctgctca atttggcaat cttgccatct
    22321 atatctttgc cagcatcatc cttgtcgcct atttaggcaa atacatccaa tacgaagctt
    22381 ggcgatggat tcaccgcctg gtttacctag cctatatttt aggactcttt cacatctaca
    22441 tgataatggg caatcgtctc cttacattta atcttctaag ttttcttgtt agtagctatg
    22501 cccttttagg cttactagct ggtttttata tcatttttct atatcaaaag atttccttcc
    22561 cctatctagg gaaaattacc catctcaaac gcttaaatca cgatactaga gaaattcaaa
    22621 tccatcttag cagacctttc aactatcaat caggacaatt tgcctttcta aagattttcc
    22681 aagaaggctt tgaaagtgct ccgcatccct tttctatctc aggaggtcat ggtcaaactc
    22741 tttactttac tgttaaaaat tcaggcgacc ataccaagaa tatctatgat aatcttcaag
    22801 ccggcagcaa agtaacccta gacagagctt acggacacat gatcatagaa gaaggacgag
    22861 aaaatcaggt ttggattgct ggaggtattg ggatcacccc cttcatctct tacatccgtg
    22921 aacatcctat tttagataaa caggttcact tctactatag cttccgtgga gatgaaaatg
    22981 cagtctacct agatttactc cgtaactatg ctcagaaaaa tcctaatttt gaactccatc
    23041 taatcgacag tacaaaagac ggctatctta attttgaaca aaaagaagtg cccgaacatg
    23101 caaccgtcta tatgtgtggt cctatttcta tgatgaaggc acttgccaaa cagattaaga
    23161 aacaaaatcc aaaaacagag cttatttacg aaggattcaa gttcaaataa gtaatcatac
    23221 tctcctggga tttcccagga gagtttttta tagccaaatg aaataagaca ggaacgatgg
    23281 aattttggca ttcaaatcaa ttgataagaa tgttttatag tggagtgaaa taggatacga
    23341 acaaattgat taggaaaatc aaatgaattt atagaaatct tttagcagtt atgttgtcct
    23401 attctagttt caaaacgcta tagaagcagc attgtgctag tctagattca gtttactata
    23461 ctaaaacgag tagcttgaaa tcaaaaaacc caccctcaca ggcaggtttt atctgtatta
    23521 ttcagctaga ttatgcttta ccttctgaac cgaatacgtc gatacgttct tcaaccgatg
    23581 cttggatagc ttttacaccg tcagccaaga atttacgtgg gtcgaagagt tttttcttgt
    23641 cgtattctgc ttcgtttgct tcgtagtcac gagcaaattt acgagttgcg ttagcgaatg
    23701 cgatttggca ttctgtgtta acgttaactt tggcaacacc aagtttgata gctgcttgga
    23761 tttgctcatc aggaatacct gatccaccgt gcaatacgat tgggaatcct ggaagagctt
    23821 ctgtcaattt ttgcaagtgg tcaaggtcta gaccttccca gtttactggg taagggccgt
    23881 ggatgttacc gataccagct gccaagaagt cgataccagt ttcaaccatt gctttagcgt
    23941 cttcgattgg agccaattca cctttaccga tgattccgtc ttcttcacca ccgatagtac
    24001 caacttcagc ttctactgag atacctttag cgtgtgcttt ttcaacaact tctttagcca
    24061 atttaaggtt ttcttcaact ggaaggtgtg aaccgtcaaa catgattgaa gtataaccaa
    24121 cttcgataca ctcaagtgca tcttcgtagt gaccgtggtc aaggtggata gctactggta
    24181 cagtgatacc cattgattca acaaggttag cgatcaagtt gcgagcaact ttgtaaccac
    24241 ccatgtattt agcagcaccc attgaagttt ggatcaaaac tggagctttt ttagcttctg
    24301 ctgcgcgcaa gatagcttga gtccactcaa ggttgtttgt gttaaatcca ccaactgcat
    24361 aaccgttgtc acgggctgct tggacaaatt tttctgctga aacgattgcc attttatcag
    24421 gcctcctgta tatttttatg ggtcatccca tttacattgt tcattttatc actttttgcc
    24481 aaaaaaatct agtttttccc gcagtttcga ttgattttct tctaactcca tctatgtaaa
    24541 ccctttctcc ctagtcttgg acgacttttg gaaaatctat aaagaaggtt aaacgattct
    24601 cctccatctc gaaacgataa gctaattttt catgttctaa tagactctta accacaaaga
    24661 gccccatacc agaccccttg accttgcgac tagcattgtc agaaaaagac tgggctagtt
    24721 tttcttgttc ctctgagcta cagctatttt cgataaaaag ttctccttct ctttctccaa
    24781 ttcgaactaa gccacctgga acagagtgct taatggcatt gctgatgaga ttagaaagaa
    24841 tcaacttcat aactgatggg tttagataag cctgctgatg ggtcaaacta ttgtctatct
    24901 ggagctctct ttcctttgct agcaaggcat aatctttgac cagattttgc gtcatctgga
    24961 ggaggtcaat tgtttcccta tcatctcgca attcctgcac agaagagagg gaaagtatct
    25021 gcagaacatg gtgattgagt tcatccacaa tccccaaggc aactcccaga tactggtctc
    25081 tatccttata acgaccgata ttctctctca tattttcgat taggattttc aaactagcca
    25141 gcggtgtttt caattcatga gaagctcctc gtaggaattc gaccttcatc ttctccagct
    25201 ggagaatggc ttcattcttt tcatgcaagt ccgcaataac agtcaagaga tgctggtaga
    25261 ggctattgat ttgttccttg agattaccta tctcatcctt agaatccacg cgcaatcgca
    25321 cttgggaatc caggtccatc atccgacggg tcacccgctt gatttccaaa atcggtgcaa
    25381 caatagtccg agcgtagatg taggccacca agagggaaat cagaaaggag gccagcaagg
    25441 tatagggaag aaactggaga ctgatttgct ccgcttcctt ttgtaaatcc atggaagcta
    25501 gaaactggag aatcatagta ccaccgtctt gcgttttcac ctcgcgctcc tcaataaaga
    25561 gagaggttgt ctggcggtct gtgtccagag gaagactgtc cttgacttct aacttgtcct
    25621 cggtcatctc acctttgacg gtccccttga tatcactagt ctgggaatac aagtctaaca
    25681 cttgctcgat actctgccta tctttccctt ctagggactg ggcaatggct gttgcctttt
    25741 gaccaatggt ttcctgacga tgactcagat aagtcgaagg aaaaagaaaa taaatagcta
    25801 aatgaaggca gataaccaga acactaaata tcgagaaggt atagataaat atctttgcaa
    25861 ataaacctgt tcgtttcatt ttcgctccaa tttataacca acattgcgca cagtgaggat
    25921 acaatccaag tctagctttt tccgcaattc cttgatataa acatcaataa cacggtcaaa
    25981 gggaacctca tctgtcgctt tccagacggc atcgataatc tgagatcgag tcaaggcccg
    26041 gccttcattt ttcactagat agtccagaat ttccaactct ttggcattga taggcacttc
    26101 ttgacctgcg aggcttgcac tgtagctttc aaagtccacc ttggtatcct tgtaagaaaa
    26161 gattcgtcct gtatcgtagt agcgcttgaa aatcgcgtcc accctcactt ttaaaaggga
    26221 gagggagaaa ggtttttcca gatagccatc tgccaaagag gcaaaggcac tcatcttgta
    26281 ttcctcatct tgaaaagctg tcaacatcaa gacaggaacc tgactggttt tacgaatctc
    26341 agctaggact tctaagccgt tgagcttggg catctggata tccagtaaaa ccagggccac
    26401 ctcatagcta gaaaattgct ccagagcttc ctgaccgtcc gctgcctcaa tagtttcata
    26461 gccacaatcc gtcaaataat cactgacccc ctcacggatc atctcttcat cttctacaat
    26521 taaaattttc atactttaac tgctctctat tttttatttt tcttagaata aatacctacc
    26581 ctattttcta ttatagtctc ttgctggcct tttgtctgca agcaactgac cactagataa
    26641 aacgttgtga aattcctttc tcataaattc cataacttta gtatattata tttaagcact
    26701 aaagtacaaa gaaagcaact gaaagcaatg attttcacca ctgctttcgg atttattttg
    26761 aattgttaaa tagccattcc tatccactat tcttgaatag aaacacaaga tgcaatcttt
    26821 attctagact cattttttca aatttattca ccatccagca agagctcttt tggttgtttt
    26881 ctaaggagat tgcttgaagc aagcgccata acgagaacca ctagaaccaa ggcaaggaca
    26941 aaaatgatga taaagtctga tgtctgaatg gaaatgtcta ggctcgacaa ggtcttgcta
    27001 aagccatcta cttctgcacc accaccaagg ttagaggctt gagccgcctt actagcctgt
    27061 ttggcaacac ctgaagtcac attggcaagg acagtgtttc caattgcacg ggcagtgtaa
    27121 ttagctagga agtaagcaga aactagagca gggatagcaa tcaagataga ttcggtgatg
    27181 aattgaccca agatacttgc ctgcttgagg ccgatagaga ggagaattcc cacttccttg
    27241 cgacgggcgt tgatccaaag gctgagcaag agggcaagga ggagaactga gaagctcaag
    27301 ctaccccaga agaggaggtt ggccatcttg tacataccag agatagattg ctcaagagct
    27361 gggtagttag aggagctctt gacgagtgtg tagctcttcc agttgatacc actgatgcca
    27421 ttcaactctt tcataacatc atccaagttc ttgtctgctg ttacaaagaa ggttgcgtcc
    27481 ccataaatgg ctgtgtcttc tgtgtatcca taaagttttg cagcagtgtg aatgtctgta
    27541 atagctgtgt tttcgtaaag ttcttgtgag taggttactg ctgacttatt atgaccatca
    27601 aagagtccct tgattgtcac ttcaactgtt tccttggctc ctttttcatt atctgcatcg
    27661 tagatattag agtccagttt aaccttgtcc cctactttcc agccgtgttt ggctgccaag
    27721 tccttgtgca agaggatttt atccttgtcg tcgttggtta agtgctctcc ttcgactagt
    27781 ttataagaac cagagacaaa cttgtcttct ttagaggagt cattgacacc tgtaatcatc
    27841 aagctacttc caaaacgctt ggcacgatca gcagtgagat tcttcttggt ttctggcgtt
    27901 tcaatcaggt catatccagt caaatctccg atagcgttga tacgtttgac ataagactca
    27961 atggccttgt tttcggtgat ttttttgatg tcttcaccct tgatattccc agcaccacga
    28021 ggcgttcctt ggttgacgcg acgattgatt tgcatggaga agctattggt gatattttta
    28081 aaggtctcct gagaagcctt ggcagtagct cccttgattg acaagccgac caaactcaag
    28141 ctcgccatga ggagaataat caggaagatg acaatcgatt tgaaaaactt ccttgtaaca
    28201 taggcaaatg cgttgtgtaa catagattcc ctttctagat tttgttttaa tcattctatt
    28261 aaaataagct caaattattt actagtattg cgcgtttcag tcagtttctt atcctttaat
    28321 tcaagtgtaa tatctgacgc ttgtgccact tctttactgt gagttacgac aatcacacat
    28381 ttacctgttt tctgggcaag tgatttgagt agttcgacaa tatctccagc agttttagga
    28441 tccagatttc ctgttggctc atcagctaga ataactggag cttctgagac caaactgcga
    28501 gcaatggcaa cacgttgctg ttgaccacct gataactgga gaacattccg cttgatctgg
    28561 ctttcatcca aaccaagctc aagaagtgta ttcttgcttg cctttttgtt gaccaatcgg
    28621 atattttcca gcggagaaag ataatctatc aagttataat tttgaaagac cagggaaata
    28681 tggtgcatgc gatggtaaga atagcccttc ttacgaatat cctctccttg aaaaaggata
    28741 gaaccttcaa caggactatc tagaccagca agtagggaca agagtgtgga ttttcctgct
    28801 cctgactccc caataatact gtaaaatttt ccgggttcaa aattataatt gatctgatat
    28861 aggactgctt cagcagtatt cttataacgg taggtaacat cttgtaattg taataaagtc
    28921 atgatttctc cttcttaact aatagatgat aaaatttctt tcggtgattt tctaaataag
    28981 aataggaaac aaagggctac agataagcaa ctaagcagaa ctagaaaaac ataggattct
    29041 gcaaaagata agatgctagt tgataaactg cttgctttgg ctagtgtatc ttgtaagctt
    29101 gcctgatctc cacttgctag tagagtttgg agtaggtaag ttgtgattgc gtttcctgca
    29161 acaaatgctg gaagcaaagc tccaagagat accaaaacta cctctaaaca gaattgtagg
    29221 aagatcgagc tcttgccttt tccaagtgca agtaaaatcc ccacttcata gacccgttct
    29281 ctcaaccaga gagacaaaac cagaattaag gctccagctc ctgctatcaa catcccataa
    29341 aggaagatgg tcaggaaggt ttggaaagtt gcaactgagt ctttgatttg ttcaaaagcc
    29401 ttgttttcct tttcgacttg gtagccttga ttttccaagg ccaagttttc tacctgcttc
    29461 atgagtccgt ccatttcctt aggattttct acatagaagc gtgctgcact gacttgagct
    29521 tcactattgc ccaaaagggt ttggctactt tcatagtctg taaagacttg attttcactg
    29581 aagtcagaag acaagcctgt gaatttctct tgttttttac cagaaaagat gccgataatc
    29641 tcaaactcta ctgtttgtcc ttttccagat tcagactgac cagcatccaa gccaatcttg
    29701 tcatgaagcg aaagaccgtt cttcttagcc aattcttcgt ggataaggat tttcttggaa
    29761 tccccttttt gaaggtgtcg cccttctttt agattgaaag ccgaactggt aaaggttaca
    29821 tccttggatg aatcctcaag agccgttaag ctaaccaagt tattgtctgc agctgataaa
    29881 tcatcacgct ccacgctctg ctcgccagtc actgcttcct tgtcttttag ttttgcgacc
    29941 gtctcaagtt caggagagac attttccagc cccttaatct tgcttacaga tgctaggtct
    30001 gacaacttga atgtctgacc attctctatc ttcttaatag aaaaagatgt attgagtgat
    30061 ttataaagat tgctttctac tgttttgttg gacttcatca gagtcaaaca ggctgaaatt
    30121 ccggccaata agaccaataa aatcagaaat aaaataaaac ttctcagtcg ctttctgctg
    30181 acataagccc aagatctttg gattggattc atttgtcacc tccatatttg taagactatt
    30241 ataaaaccca aatatgaaat gtttatgaaa tacgaaaaaa aaatatcgag taggggataa
    30301 tctctagccc ctctcacacc accatacgtg ccgttcggca tacggcggtt caactaactt
    30361 ttaacgcatg tcgttcaagg taataatcca aacacgaaac cagtccacgt ttttcaagga
    30421 ctggttttga tatagcacgt ttaagtaccg acttctgagc tactatagta gattgaaact
    30481 agaatagtac acctctactt ctaaaatatt gttagaaatc gatttgactg tcctgaacga
    30541 ttcgtcctat tcttatttca ttttactata attgatagtg gtcgccccag ccagatacct
    30601 tatctgctat ccatttagga acccctaact taagcaatcc ccataatcgt ctcgatttct
    30661 tcttccattg cttccagata atcactcgta ggcgagtacg caagcgctca tctatgctag
    30721 tgactatact tttcatattt ataattcatt cctttcgttt cactcaaggc acaacacaga
    30781 atgaaaaagt gttgtgatct ttattttgtt ttataataat agtgagaaag cctatcacta
    30841 ctacaaatca cggggaggtg aataagtgag tggtacagcc actacctcgc atattttgtc
    30901 acatcattta acggtacata ataagttgta ccatctgaat aagttgctac aatatcattt
    30961 gcatgctctc cttcaccttt agcaaaggtt ggagctcctg ctggatgatt tttatttgcc
    31021 tctttcaatt tttcaataat ggcatttttt ctgtatcttt tatattatca ggatttttca
    31081 ctaagatttt gtctggatat gtcggtttag cagaaacaat ttttactgtt atttcttttt
    31141 tattcgaagc acttgtccag tttccagcat tatctttagc atttaatttt acagtaattc
    31201 ctgaactagg aacttcagta gcaggttgat tatcaacatt attcaacttt aatttcaaaa
    31261 gagctgttgc atcagacgtt ttatcaatcg ttatatataa tgatgaattg ttattataaa
    31321 cagtttcttc atatttagct gtttgtgagc tacttgaaac agaactgaaa ttatgcccac
    31381 tacctccctg attatcttca atgcttacgt ctaaatgaac ttccccacta ttatttggct
    31441 tagcaacaac tgttatagta aaataacata aaatttgcat aaatagatta ggtaaatcaa
    31501 agcaacttct aggaatgttt tagcagtcac agtgtacttt cccagcatca agccactata
    31561 actctgcaca taaaaatgga gaagatggca atcctcttct ccaaatatta acttctttac
    31621 aaaccaacta tagttgacaa agaacctaaa atcaattgat aacacaaggt caggtcggtc
    31681 aactctttca actgaagccc tgtcaactct tcccatttat caatcttgta ttggagagaa
    31741 ttgcggtgca gatagagttg ctgggctgtt ttagtgagaa cagcactatt ttcccaaaga
    31801 gagagaatga tttcctgaat ctgatcttga tccaaaatca tctggtgtag acattcttta
    31861 attggcttca agtccacgag tctttctccc atactccaaa gatagagctg agaaaaagta
    31921 tgaacacctt ggtgaccctg acgccaccat gtcttgaaca aatcccgctc agctttgatt
    31981 aagtctgata gggcttgatg tcctgtctga gaccaaacct gacccaacat gatagaaaga
    32041 cgaagtccaa agtcatactc aaccgcttca atcgtatcac ttaaaatatc tcttacagaa
    32101 gtgtatttgt cttgttgaag cacgaaaaca taatcctgag ctccgacctg tagcactgtc
    32161 tgacaattcg gaaaaagagt ccgcatcata tctagccaag aagccagatt ttcctgctga
    32221 aaataagaaa gatggcaata aaccaactga atctttttaa aaacttgcgg tgcctgtccc
    32281 ttgccttcaa ccagatagga ataccaaggg tttagcgaac gagcctgctc ctgctgggtc
    32341 aaaagggcaa ccaactgctt ttcacgctcg ctgagcccag cttcctccag caaaatccac
    32401 tgctgagaag ctaaagggag cgtgagatag ccctctttct ctactggttg gtctgaaatc
    32461 cgagcctcag gaaaccagtc ttgtagttct tttgccctca tgttctagcc ctccactttt
    32521 tggatgcacc atgaaaccaa actctcaaga cgttccagat tctcagtcat atggagatag
    32581 cccataaccg cttcaaatcc cgtggacata cgataagtca cgacatctgc atttttagcc
    32641 tttgtgtggc tattggtatt gcggccacgt ttatagattt cttcttcttt ttccgttagg
    32701 acctgctcct ccaacatgag agcaatcagg cgagcctgag ccttggctga cacatacttg
    32761 gttgcttctt gatggagttt attgggtttg gtcatacctt tgaggatgag gtgacggcga
    32821 atatacatag aatacaccgc atccccctca aaggctagcg caatcccgtt aatgagattg
    32881 acatcaatca cgtgtccacc tcactccatc ttttgtatcc aatagtttaa tgccttgagc
    32941 agccagttgg tctcggattt ggtctgctgt ctcaaagtct cgattggcac gcgcctcttg
    33001 gcgtttttga atcaagtctt caatctctgc atccaaaact tcctcaacaa agacaattcc
    33061 aaaaatttct aacatatctg caagagcttg cttgacactt gcatcatagt tccctgagtt
    33121 gatccatttg gccatttcaa agacaactgt gataccgttg gcagcattaa aatcttcatc
    33181 catagctgct acaaacttat ctttaaagtt ttgtaactct tgggcatcca cgtttcctgt
    33241 aaatggttgt tcgtaagtat tcttcagata cttgagattg gtctcggcat cgcgaactgc
    33301 cttttccgtg aagttgatag gcttacggta gtgctgggtc gcaaagaaga aacgaagtac
    33361 ttgcccatca agagttttaa gggcatcgtg taccgtaatg aagttaccca aggacttaga
    33421 cattttgaca ttgtcgatat tgacaaagcc attgtgcatc cagtagttag caaaagcctt
    33481 gcctgtttta gcttcagatt gggcaatttc attggtgtgg tgtggaaact ctaggtcagc
    33541 tccaccaccg tggatatcaa tggtatcacc taaaatctct gtcgacatga ctgaacactc
    33601 aatatgccaa cccggacgtc caggtcccca aggactatcc caagaaatct cacctggttt
    33661 ggaagatttc catagagcaa aatctacagg attttcctta cgagccgttt cttcatcggt
    33721 acgacctgaa gcacctagat ccaaatcttc caaggtttta ttagccaatt tagcatagtt
    33781 gtgggatttt tctacacgga aatagacatc cccttgactc tcataggcaa agcctttctc
    33841 gatcaagtct tccacaaaac ggatgatgtc tgccataaac tccactacac gcggatggcg
    33901 agtcgcaggt ttcacgccta aggccgtcac atcctcacga aaggcagcga tgtacttatc
    33961 cgcaacctcc tgaggcgtga tgccttcttc cctggcacgg ttgataatct tatcatccac
    34021 atctgtaaaa ttggaaatat aggcaacctt atacccacgg tactcaaaat agcgacgaat
    34081 cgtatcaaaa gctactgtcg aacgggcgtt tcccacgtgg atatagttgt acaccgttgg
    34141 cccacaaaca tacatcttga tcttgccgtc ctcaatcggg acaaattctc gcaaatcacg
    34201 agacatggtg tcatagattt taatcataaa tcataatcag gaaagctgaa atccaagaac
    34261 aattagtttc atcactaaaa gttcaagtaa atttcagtcc gaatatctct acacttcgga
    34321 atcccttgct cctttctcat tcagataaac cacctgagtc tgtttgacaa agccaatttt
    34381 ttcatacaaa cgtttggcac ctacattgct atcttccact gcaatctgaa attccttgtc
    34441 attttgctca attagttggt tgacgaggga ttttgctaag tagcttccat agccttttcc
    34501 acgttcaggt tccaatattg ctaaaccgta gaggtaattc gtattagtcg ataaatcaac
    34561 cgtacaagtt ccaataacct gaccagcttt taataaaata tatagtcggc tttctggatc
    34621 tttcagagct tcagcgacat atctatccac aacttctctc gattcatgtt cctctgaaaa
    34681 tgcctgaaat tttaattgac taatttgatc ctgatacgaa ctatctgcta acaaaatttc
    34741 aagatgggaa acatttgcta acggataagg tcttctatcc ttacctaacc aagtttctgt
    34801 ctcttcatcc tcgattagtc cccagttact ggcaaagtca ggatgattct ctaaaaaaat
    34861 acgttctgtc tgaaaagtga ctgaccgaat ggggaaagaa gctgtttctc tctcaaaact
    34921 agtaaacaat gcacgcgcaa tcccctgacg gcgatgacct ggatgaacca gtatcgtcac
    34981 ttctacatct tggtcatctg catagacagt taataaacca acaagttcgc ctttttcata
    35041 ataaaggaaa aaggcgggca tgtttgggtc aaaattaagc atgttagaga gatagggatc
    35101 gcgataggta ccgtcatagt tttggcaaca gttaattact tttttcgcct cagatagctc
    35161 ctcttggctt aacttgtttc ttgcttgaat catataggta tcctctacaa accagacgat
    35221 ctgtgactgg catctttagc ctgctcgagt ttattgacat aatactctcg tttttcttcg
    35281 acttcgtgaa tgacaggctc atctttctta ccatgaagac ggacaatctt ggccggaata
    35341 ccgacaaccg tcacgtcact aggtacatct gctacgacaa ctgctgcagc accgaccttg
    35401 gcattttcac caatttccac aggcccgata acttgggcat gggctgatat gagggctccc
    35461 tttcgtacag tcggatggcg tttgccacag tctttccctg ttcccccgag agtcactccg
    35521 tgatagagaa gaacgccttt ttcaacaatc gctgtctctc caatcaccag accagaacca
    35581 tggtcaataa aaacacctga atcaatctgg gctcctggat gaatctcaat ctgagtccaa
    35641 aagcgccaaa actgactgta catacgagct aatagtttga agccgtgctt ccagagaaaa
    35701 tgcgagagac ggtgggccgc caaggccttg acacctggat aagtcagcaa aacctccaaa
    35761 gtggtgcggg ccgctggatc attttctttt acaatatcaa tggtttcgcg ccaccacccc
    35821 atacatttct ccttttctta ttctgaatct tttggtgttt ctgtaaattc tttcttaggt
    35881 ttgtaatcct tgtgatgacg tgggcggtga gggcgctcag acttttcacc tttttcatca
    35941 tgctcaggtt ttggcggacg aggtagaaga gccttcatag aggcatcgat acggcctttt
    36001 tcatcaatct tgataacctt aacatcaact tcatccccga tttctaccaa atcctctaca
    36061 cgattggtac gagtccaagc catctcagag atatgaacaa gggcatctgt cttatcaaag
    36121 aggttaacaa aggcaccaaa tttctcgata cgaacgactt tagcacggta aacttcatcc
    36181 actttggctt cacgaaccaa accagcaata atttctttgg cacggttaat agcatcttgg
    36241 tcactagagt agatagacac atttccttct tcgtctatat caatcttaac acctgtttca
    36301 gcgataatct tgtcgatggt ttctccaccc ttaccgatga caatcttaat cttgtccaca
    36361 tcaatcttga tcgtatcaat tttcggagca gttggagcca attctagacg aacttctgga
    36421 atggttgctt caatgacatc aaggatttca aaacgcgctt tcttggcttg agcaagagcc
    36481 tccgtcaaga tttctgcagt aatcccttga atcttgatat ccatttgaag ggctgtaatc
    36541 ccatcacgag tacctgcaac cttgaagtcc atatctccaa agtgatcttc caaaccttgg
    36601 atatctgtca atactgtgta gttatttcca tctgagataa gtcccatagc aataccagct
    36661 actggcgcct tgattggcac accaccagcc ataagggcaa gagttcccgc acagatagaa
    36721 gcttgagatg aagaaccgtt tgattccaaa acttctgcta ctagacggat agcgtatggg
    36781 aattcttcca agcttggcaa gacttgagca agagcacgct caccaagggc accgtgaccg
    36841 atttcacgac gacctggcgc accgtaacga cctgtttccc ctacagaata ttgagggaag
    36901 ttatagtggt gcataaagcg tttcttgtac tctggatcca aaccatcaat gatttgagtt
    36961 tctcccatcg gagccaaggt caagactgaa agagcttgag tttgcccacg agtaaagaga
    37021 cctgaaccat gtacacgagg aaggaagtca acaaccgcat ccaaaggacg gatttcatcg
    37081 accttacgac catcaggacg caccttgtct tctgtaatta aacgtcgcac ttctgcgtgt
    37141 tccatttgtt ccaagatttc agccacatca cgcataatac ggtcaaattc ttcgtggttc
    37201 gcatattttt cttcgtaaac ggcagtcact tggtctttca ctgcttgagt tgcagcttca
    37261 cgggccaatt tctcttctac ttgaactgcc ttttggaggt cactgttgta ggctgcaatg
    37321 atttcagctt gcaattcagc atccacgtga agcaattcca cttctgcttt ttctttaccg
    37381 acagcagcaa cgatttcttc ttggaaggca atcaattctt tgacagcttc gtgcccttta
    37441 agaagcgctt ccaacatgat ttcttctgac aattctttgg caccagactc taccatgttg
    37501 atagcgtgct tggttccagc tactgtcaat tcaagaagag attgctctgc ttgttcttga
    37561 cttgggttga tgatgatttg gccatctaca tatcccactt gtaccccagc aattggtccg
    37621 tcaaatggaa tatctgaaat agacagtgcc aaagatgaac caaacatagc agccattggt
    37681 gcagatgcat tttcatcata agaaagcact gtattgatga cttggacttc attacggaaa
    37741 ccttccgcaa acataggacg aatcggacgg tcaatcaaac gcgctgtcaa ggtcgcatct
    37801 gttgaaggac gtccttcacg tttcataaag ccaccaggaa acttcccagc cgcatacatt
    37861 ttttcttcgt agttgacttg gagtgggaaa aaatccccag ttgccatttt cttagacata
    37921 acggcagcag tcaagacagt tgactcaccg taacgtacga caacagagcc atttgcttgc
    37981 ttagcaacct gaccagtctc tacaattaac tcacgacccg caaaagtcgt ttgaaacact
    38041 tgttttgcca ttttaatccc ctttggattg atgaaattat acgccttgcc tacaaagatc
    38101 aagataccaa ggacgtcaaa agcaaagtaa aaataggaaa ctgacgaagt cttcgatgaa
    38161 gacaagacag tttatctttt ttacacagct tttcggccgt gttcaattac tcaagatgct
    38221 aagccgtcaa gcaactcaaa ggaaaatagg aaatcgaacg acggagcgac tgctcctagg
    38281 cagatttatc tttttccaca gagttgtagg cgtgttcagt tttcaagata catcattaga
    38341 aaggtttaat attaaagtat ctaaaccttt cacgctaatc gctatcgggc gattagctaa
    38401 atgctttact aactctttcg tcaaataaca tcgatttgac tcactcgtgt cgttaaatct
    38461 tacagtttaa atgcattgta ttatttaata ccttcatctt tgtatcaagt acgtacagaa
    38521 tctattttat catatttttc ttaaaaagtg aggtctttac cattaaaaag gaaccattcc
    38581 cctcacctga gaagaatggt ttgcttttat tatcctagag actggtgatt aaacaaggca
    38641 tgggttgctt gatggatgta ttttgctgta tcagcattat tcatcgtata gagatgcaca
    38701 ccggcaacat cctgagttac caagtccacg atttggtcca ctgcataggc aagtcctgct
    38761 gctctgagcg actcagggtc atgctcatac ttgtctaaga tggctttaaa tttgcgtgga
    38821 agatggatat tctcacaagt cttcaagagt cggagagcct gatttcgatt cagaattggc
    38881 ataattcctg catgaatggg aacatcaatc ccagccaaga tacacttgtc ctgaaaatca
    38941 tagaagcgct cattgtcaaa gaagagctga gttacgaggc tcgaacagcc tgcatccact
    39001 ttcttcttaa gattttgaat atctgaaatc tgatttggcg aatctggatg cccttctgga
    39061 tagcaagctc caataatatc aaagtgaggg gtttgttcct tgataaactc aatcaagtcg
    39121 gttgcatagc ggaaatcctt ttgtggttcc acgtctggaa taatatcccc acgaagagcc
    39181 aagattttct gcaccccaac tttgtccaag tcagcaatag tttcagcaac cttgtcctta
    39241 gttagataaa tagctggcaa gtgggcaatg gtcggaatcg ccaaatcatt ttggataaag
    39301 tcagccaaac gaaccgtcgt ttccttgata ttaaatttat tattgctggc agttacactg
    39361 ataaaatggg gagccaactc ctgcatatcc tgcaaggctg aaataatgtt atcattaccc
    39421 acggctgggt ttggagggaa cacttcaaat gagagtgacg gtgtttggcg tgacatatgt
    39481 aataaccttt tctagttgat ttctttttga acaaccactg tatggagaga aatccaatct
    39541 tacaatttct cacgcgcagc tttagctgct tcaacaaggc ggatcaagct ttcttttgtt
    39601 tctgggatac cacgtgtttt caaaccacag tcagggttga tccaaacttt cttgcttggc
    39661 actttagcaa ggatggcttc gattgtgttg tcgatttcgc cttcatttgg tacacgaggt
    39721 gagtggatat cgtaaacccc aggtcccact tctgtttgga agtttttcgc tttgagttcg
    39781 tccaagattt caaggtttga acggttagct tcaaaggaaa taacgtctgc atccatgtta
    39841 tcgatagctg ggatgatatc tgtaaattct gagtaacaca tgtgagtgtg gatttgtgtg
    39901 tctggcgcta ctgttgagtg taccaagcgg aaggcaggaa tagcccagtc aaggtagtct
    39961 tcgtaccagt cgctacggcg gagtggcaat ttttcacgaa gagcagcctc gtcgatttgg
    40021 atgattttca caccagcagc ttcaaggtca agtacttcat ccttgatagc aagggcgatt
    40081 tggagagttg aatccttgat agagatgtct tcacgtggga atgaccagtt aaggatggta
    40141 acaggtccag tcaacatacc tttaacaggt ttgtttgtac gactttgtgc atagctagac
    40201 catttaacag tgatagggtt aagacgagtg acatcacccc agatgattgg tggttttacc
    40261 ccacgcatac cgtatgattg tacccatcca tttttagaga agaggtatcc tgacaagttt
    40321 tgaccgaagt actcaaccat gtcattacgc tcaaattcac cgtgaacaag gacatcaaag
    40381 tcaatatctt cttgccactt gatccattcg tcaatcgttt cagcaaggaa agcgtcgtac
    40441 tctttttgag acaattcacc tttacggtaa gccaaacgtt tggcacgaac ttcttttgtt
    40501 tgagggaatg aaccaatcgt tgttgttgga agagctggaa gtttgaaagc ttcttcttgg
    40561 atagcttcac gttctgcaaa ggctggcaaa cgagtgtagt ctgcgtctgt caagccagcg
    40621 atacgcgcac gaagttcagc attttcacca acacgctcag tcgcaaagag ttctttgttg
    40681 gctgcaagag cttctgaacc ttgaccattt cggatagcat ccaagtcacg gatttcatcc
    40741 aatttttcaa ctgcaaaggc aaagtggttc aagagtgctg gttcaaattc ttcattagca
    40801 gttgtaaatg gcacatgaag aagtgagcaa gagcttgtca aaacgatgtt ttcagctgga
    40861 atttgctcaa gaacagccaa gctcttttcg tagttgttgc gccagatgtt tttaccattg
    40921 acaataccta catagagagt cttgtcagct gggaagccac ctttaacgag ttcaagagtt
    40981 ttcttacctt caacaaagtc aagaccgata gcatctactg gtaagtttac aaggtcagcg
    41041 tatacgtcac gaacatcacc gaaataagtt tgaagcaaga cttcaagacc ttttttgtca
    41101 gccaagagtt tgttgtaaag gttcaagaag agagcttttt cttcagctgt caagtctttt
    41161 acaagagccg cttcatccaa ttggatgcga gtcgcaccaa gttcagccaa tttagcaaaa
    41221 acttcttggt aagcagccac taagctatct acgaagtcgt ctgctttcac gccttcttca
    41281 aagtctgaca attgaaggaa agtgaaggga cctacaagaa caggacgagt gttcaatcca
    41341 agttctttgg cttcttggaa ctcatcgaaa atcttgtgac cagccaattt tacttgagtg
    41401 tctttttcaa atttaggaac gatgtagtgg tagttagtgt tgaaccattt cttcattgga
    41461 agggcgcgaa cgtccccttt ttctccctgg taaccacgtc ccaaagcgaa gtagcgctca
    41521 aggtcagaca agtccaagtt ttgaacggat gcaggcacca cgttgaaaag gaaagccgca
    41581 tctaggaagt tatcatagtg agaaaagtca tttgatggaa tttcagtgat gcctttttct
    41641 ttgacaatgt tccagtgttt agcacgcaag tcttttgctg ctgctaaaag ttcttcttct
    41701 gagatttctt ttctaaagta tttttcagtt gtaaatttta attcacggaa ttcgcccaaa
    41761 cgagggaaac cgatgattgt agttgacatg atgtgtcctc caaaatttgt tgttgaaact
    41821 atcttaacag aaaagaaagc gtctgtataa ttgtaaaaaa ttagggtttg atatagtttg
    41881 aaactatata tctgtttcgg acaaaagaaa aagacttgaa gcaaacgtct caaatccttt
    41941 gtaattctta ctttacagct atattccaat tagaatacta aaacatgtta ttagtaattc
    42001 ttataagtga ctatgacctg ttattagaaa agactataac tgattctagt caactttttc
    42061 cctgttcaag tgggacgatt gctagtgtct ttcctaaact ggctaggact tttaagactg
    42121 tatccaactg aggactagtc tttcctgtct ccatcctagc tatgacaggc tggcttattc
    42181 cactgacttc ttccagcttt ttctgactga ttccttgttc atacctagcc tcaatcaact
    42241 cgctcatgat agccactcgc atatcacttt caaggatttc ctccttgcta aagagctcag
    42301 atggacatcc ttccaattac tcccaatagc actattcttc atcacttaac cctctttttt
    42361 ttacgtctat gtatttttaa aaaaatgagc gaattatgat tcgatagatt gaccagtggg
    42421 tttaaagttg gtgctagcct atttcttaag cgattttcct tttctaggat aaagcagttc
    42481 ctgcttgctt aaccccaatt ttccacgatg aatccaatag taaatggttg aaattcccac
    42541 gttaacccct ttagccatca ccatcatttc aggcgaaaat ttttggttat gtttttggtt
    42601 atgtatagtg gagaatcttt tcctttagtt tcttaagact gttgagcgta gtcggcagaa
    42661 taaatctctt tgaagcgccc ttttccaaga cattgtcgga ctgtcccacg cttgatttca
    42721 gtgtggatag tttgaggagc ttttccaagt agagaggcaa tttctctatt tgattttcct
    42781 tcttttttcc atcgttcgat taagcgacgg ctatcgattg tcaaatgttt gccttttgta
    42841 gtataattgt cttgcatttc tgtgcctttt aatcatttca atcttaaatt ggactttttt
    42901 tacttgggtt gtacttaatc tatgaggaag acaagaaaaa gaatatcaat caagtaaagt
    42961 cacaaagtca cattagctcc gagcaaccat tgcaaattga ggtactcaca caatgattaa
    43021 aacatttctc tctgcccttt cggtcattct cttttctatc cctatcataa cttattcttt
    43081 tttcccatct tctaatctta acatttggct atctacccaa cctatcttgg cacagattta
    43141 tgccttcccc ttagctactg caactatggc tgctatttta agtttcttat tttttttcct
    43201 atctttttac aagaaaaata aacaaatacg gttttactct ggcattttgc tcttactatc
    43261 gctcatatta ctattattcg gaacagataa aaccctttct tctgcatcaa ataagactaa
    43321 aaccttaaaa ttagtaactt ggaacgtcgc taatcaaata gaagcacaac atattgagcg
    43381 aatttttagc cattttgacg ccgatatggc tatattccct gaactagcta ccaatatcag
    43441 aggtgagcaa gaaaaccaga gaatcaaact attgtttcat caagttggac tttctatggc
    43501 caactatgat attttcactt ctccacctac caatagtgga atagctcctg tgactgtgat
    43561 tgtcaagaaa agttatggtt tctatacaga agctaaaact tttcatacaa cacggttcgg
    43621 gacaattgta ttacattcga gaaaacaaaa tataccagat atcattgcct tgcatactgc
    43681 tcctcctctg ccaggtttaa tggaaatctg gaagcaagac ttaaacatca ttcataatca
    43741 attggcttca aaatatccaa aggctattat tgcaggtgat tttaatgcaa ctatgcgtca
    43801 tggagcactt gcaaaaataa gctctcatag ggacgcatta aatgcactgc caccttttga
    43861 aagaggaact tggaatagcc aaagtccaaa actttttaat gcaacaatag atcatatttt
    43921 attgcctaaa aaccactact atgttaaaga tttagacatt gtaagttttc aaaactctga
    43981 tcatagatgt atttttacag aaatcacatt ttaattattt tatataaaat cacccctcta
    44041 atgttcataa actagagggg gaatttgtat cctactatcg tttaacgcac ttctgcattc
    44101 actttttctt cgagagacgc ttggattttt tccatatagc gtgcgacttc ttcgtccgtt
    44161 aagctgtctt ctggattttg gaaggtcaag ctataagcca ttgacttcat accaagtccc
    44221 agtttttcac ctgagaagac gtcaaagagt ttgatatctg tcaaacgttt cacgccggca
    44281 gcttggatag catctacaac ttcttggtga gtcacttctg ccttgaggag aagggcaacg
    44341 tcacggctga ctgctgggaa tttggtgatt tccacaaatg gaacagcagg ttggagcgcc
    44401 ccttcgatgg ctgaaaggtt aagctcagct acatacgttt ctggaatatc gtaagccttg
    44461 gcagtgactg gatgcacttg gccaaggaaa ccaagaactt ggtcaccgag tgaaatcacg
    44521 gctgtacgac ctggatgaag gctaacgatt tcagatgttg ctgtataggt tacttggagt
    44581 cccaaacgag taaatagggc ttcaaggatt cccttagcat agaagaaatc aactggaact
    44641 gctgctgttt ggaaatcttt ttcagcaacc aagcctgtca aggcaaaggc aaagctgttg
    44701 atctcatttg gaagttcttc ttttggatta cctgtttgtt caaagacttt tccaatctca
    44761 taaagggcca agtttttatt cttacgagcc acgttgtagg caacggtatc aaggatccct
    44821 gaaatcatat tttgacggag gactgaacga tccacagtca ttggccacat gagttcagta
    44881 aggttacttg gttgagctgt gaactcaact gctttttcag gagttgtcag agcataggtg
    44941 atgatttctg tcaaacctgc tccttcagca atggtacgaa cttgacggcg gagtttttgt
    45001 atcacagtca attcaccagc tgtaccatcg tcttttggaa ggctggttgg caagcggtca
    45061 tatccataga tacgagcgat ttcttcaaag agatcagctt cgattgtgat atcccaacga
    45121 cgacgtggta cgctgactgt aaagctgtct gcatttccag aaagaccaaa gccaagacga
    45181 cggaagacgt cttctacatc agcataagac agctcagttc cgaggacacg gttaacatca
    45241 gcaagggttg aagaaacttc cacatcagag gtatcaagct cacccgctga aacgataccc
    45301 ttacgcaccg tcgcgcctgc aagctctgca atcatgctag ctgccgcatc aagggcttca
    45361 ttaactgttg ccacattaat tcctttttca aagcgagaag atgactcaga acgaaggttc
    45421 aggcgaccac ttgtcttacg gatagatttg ccattaaaaa cagcagcttc aaggataaca
    45481 cgactagatt tttcagaaat ttctgtagcc tgaccaccca taacaccggc aagggctact
    45541 ggtttgtcag caactgtaat cacgaggtct gtctcagcca agtctcgttc ttcaccgtcc
    45601 agggtcacta atttttcacc atcacgcgct tcacgcacac ggatgtcagt cccttcaaat
    45661 gtgtccaagt caaaagcatg cataggttga ccaaagtaga gcaggatgta gtttgtcacg
    45721 tctacaacgt tattgatggg acggatgcct tcgttcatga gaaggttttg caaccattgt
    45781 ggacttggtg cgatagtcac attgtccaag atacgagctg catagtaagg cgccttgtct
    45841 gtctcaatgc tgacagaaag ggcatctgcc gcagcttcat tagtttctgt tagagtaaat
    45901 tttttaaagt tgactgcctt gtcatagatg gctgccactt cgtgagccac tccacacata
    45961 gaaagggcat ctgcacggtt tggtgtgatg gaaagttcga tgatttcatc atccaagtct
    46021 aggtaagaaa agacttcctc acctggcacg gcatcttcag gcaagatttg gatgccatct
    46081 gcgaattcct taggcacaac tgagtcagaa attcccaatt caccaagtga acagatcatt
    46141 ccaagtgact ccaaaccacg gatttttcct tttttgattt tgtagttatc agcgatacga
    46201 gctcctggaa gagccaccat gaccttgatc ccagcacgca catttggggc accacaaacg
    46261 atctgacgct cttcttcttc gccaacgtta atctgacaaa catggaggtg agtctctggc
    46321 acatcttcgc aagacaagac ctcaccgacg acaatttttg agagaccagc agctggtgat
    46381 tcgacaccct ctacctcgat ccctgtagtt gacatttttt cagccaactc ttgtgatggc
    46441 acatcaatgt ccaccaattc ttttaaccat ttataagata caagcataat ttagttctcc
    46501 agaatgacag ttgtcactct agttcttttc ctttcctatc atttcaatag aagaatcctc
    46561 ttcttacctt aatttctttc tcagtaacca atccgtatct actttttgac caaccataaa
    46621 atgatgttgg ctaaattttt caaaaccata tcggttataa aacgcttgag cttttgtatt
    46681 atgctcccaa acacctagcc aagcccaaga aaaactattt tttgtagcaa gttcaagtgc
    46741 gaattcaaac agttgcttac ctagtccaaa tccttggaat ttttgtagca catagagacg
    46801 ttgaatttca aaagcgtcct ctaattctct ctcagtttga gcacttcccc agttgacttt
    46861 gagaaaacca gctatctcct cctcatgcat aatgaaatag gtttcagagt caggatttcc
    46921 caactcagtt gacaaagttt tcagactata agcctcttca aagtattcct gtaactgctc
    46981 ttccgtatta tcatacgcaa aggtttcacg aaaggtttgt ttggcaattt tagccaacac
    47041 ctcaacatct gccatttcta cttttctaat cattatttaa actgttctga gaagcggaca
    47101 tctccttggt agaatccacg gatatcgttg attccataac ggagcatagc tacacgctct
    47161 tgtccaagac caaaggcaaa gccagagtat acagtcgcat cgataccact catttcaagg
    47221 acacgtgggt gaaccatacc ggcccccata atttcgatcc aacctgtttt cttacataca
    47281 ttacagcctt ctccaccaca cttgaagcaa gaaacatcca cctcaacaga tggctctgtg
    47341 aatgggaagt aagatggacg caaacgaatt tgacgctctt caccaaacat tttttggaca
    47401 atcaactgaa gcgttccttg aagatcagcc atagagatat ttttcccaac taccaagcct
    47461 tcgatttggt ggaattggtg actgtgggtc gcatcgtccg tatcgcgacg gaagacacgc
    47521 cctggcgaga tcatcttcaa aggaccttta gaaaaatcat gggcatccat agcacgcgcc
    47581 tgaactggag acgtgtgggt acggagcaag atttcttcag tgatatagaa agtatcctgc
    47641 atatcacgag ctgggtggtc ttttggaagg ttcatacgtt caaagttata gtagtcttgc
    47701 tccacttcaa aaccatccac gacttgataa cccataccga tgaagatatc ttcgatttct
    47761 tcactggttt gtgtcaaaac gtgacggtga ccagtcgcaa ctggacgacc tggaagcgtc
    47821 acatctatac tctcgctagc cagttgagcc gcgactttct tttcttccaa gagcttagct
    47881 gtttcttcaa aagcagcagt caagacatca cgagcttcat tgacgtgttt cccgatgatt
    47941 ggacgcatct cagcagaaac atctttcatc cctttgagga tttcagtgag cgaacccttt
    48001 ttaccaagga cagagacacg caaatcttgc atctcttttt catttccagc agtaatctgc
    48061 ttcaagctag ccagcgtttc ttcgcgaagc gcttttaatt gttcttcaat agttgacata
    48121 tttcctccat cagtctctcg tagataaaaa gaaaaccaca tgccaaaaac tccactcgga
    48181 gcgttgacac gcggtaccat ccgttttcat ctgacaagtc agaccttcat ttctaaatcc
    48241 atgcgcaagt gaattcaccc agctttcata tagagagctt gcagtcacgg ctctcctccc
    48301 tgatatactt cccttgggct actagtcttt cagattccta ttcaattact acttagttta
    48361 tcagattttt accattcttg caagacctat cttacttctg cttgttagct tattcttatc
    48421 taaatttata taaacaattt atctaaatta actatttata atttttgtaa caaaattaaa
    48481 ttaattgaca ctcccctata aaataaagaa gtttagaatt taatgtcttc caaacttctt
    48541 tattccatat ttaatgaaat gccaccttaa ccgtgataat agctagtcat caataaaaaa
    48601 ctatttgaat aaggattctc catttgattc aatcacttct ttataccaag taaaagacat
    48661 tttcttatat cgatttaatg taccacttcc atcatcgttt cgatcaacat aaatgagacc
    48721 gtacctttta gaaagttgtg cagtggacat agaaacacag tcaatacatc cccaagacgt
    48781 atagcccata atttcaacac catcctgtag agcttcagca acttgcaata aatgttcttt
    48841 catatactga attctataat catcttggac ggttaagtta ttaagttcat cttttattag
    48901 ttgatcttta gcacctaatc cattttctac tataaataat gggatttgat aacggtcata
    48961 atatctattt aaaattatac gtagtccaat tggatcaatt tgccatcccc actctgaaga
    49021 ctctaaataa ggatttacta aaccaccaat aatattccct tctcctgaat tatactgtgt
    49081 tggaagagca gattgagtca cactcatgta atagctaaag gataaaaaat ctacggtata
    49141 attttttaat aactctgcat cttcagctgc aaactctatg ttaatgtcat tttccttaaa
    49201 atatcttttt gcataattcg gataataacc tctaacatgc acatctgaaa atagataatt
    49261 tagattctca tactcatgag tcgcccatac atcttttgga tttggagtca ttggataagc
    49321 tggcatagct aataccatac atcccacctt aaactctgaa ttaatctcac gagcaatttt
    49381 tgtaaccaaa cttgaggcga ctaattcatg atgtatagct tgatataatt cttgtttcga
    49441 aagattctcc ttaggtatat ctattcctcc actagtaaat ggtaattcca aaacagagtt
    49501 tacttcgtta aatgtaagcc aatatttaac tttatcttta tacctttcta aaactgttcg
    49561 agcaaatttt tcataaaaat gaatcattct cctatcaacc catccatgat attttcttgc
    49621 taaatataat ggagtctcat agtgtgaaag agttacaagt ggttctatcc cgtgagcatg
    49681 tagttcatca aacaattcat cataatattt caacccagct tcgttaggtt cttcctcatc
    49741 tccttttgga aaaattctac tccatgcaat agaagtacga aaaacattaa agcccatttc
    49801 agaaaacaag gatatatctt ccttatattt atgataaaaa tcaataccta tcaattttaa
    49861 gttatcttct gtaggatttt ctgttgcttc tcctaatcca cctttgggta acacatcctg
    49921 aactgataag cccttaccat cttcattata tgctccctct acttgattag ctgcaacagc
    49981 tccaccccaa agaaaatcat ctggaaaaat ggtcataact ttcctccatt ataatattac
    50041 cagtaattcc ttagaatgct cgattgtctg attattaggt aatactaata catctagaaa
    50101 atcattggta ttcgttacaa ttactggtgt aactgtttcg tagcctttag tcttgattaa
    50161 attcaagtcc atttcaaaaa tcaactgatt tttgaaaact ctgtctcctt cttctacatg
    50221 actaataaaa ccttgacctt ttagctcaac agtatctaat ccaatatgaa ttagtaactc
    50281 aacaccctca tcactcttca atccaattgc gtgcttagtc ggaaaaatat ttgtaatttt
    50341 cccatcaaat ggtgcataaa ccttaccttc acttgggata atcgctactc cgtctccaat
    50401 tagtttatct gaaaatgttt tatcctggac atcgcttaac ggaatgattt ctcctgatat
    50461 aggagaaaat atcatttttt tatttgaaac tccagcttca acttctaaat tgctagaact
    50521 ctcttcttca tcgattccaa atatataagc taatacaaag gtaataacaa ccgaaatgac
    50581 cgccacaatt aaagcattta caatatttga tggcacatca gaataaataa attgaggcaa
    50641 cgctatcaaa gatgggacag caaatagata tgctttaaca ctagtaagac ctgcaaataa
    50701 tcccgctaat ccaccaccaa tcatagctgc ataaagcggt tttttatatt ttaaagtcac
    50761 accatataat gcaggttcgg taatccctgc aagtaaggct gagaaacctg ctgcaaaagc
    50821 aatttgtttt gtattattat ttttactctt taatgcaaca gccatcgaag cagccccttg
    50881 agctaagttt gaccctaaca ttgctggaag aattaatacg tctggagtag caatagatgc
    50941 cgccaaaaaa ataggtgcaa aagcccaatg cattccagtc ataacaataa atggcataat
    51001 agcaccaaga atagctaatg taagccatcc agctacacca tacatttgcc caactagatt
    51061 tgataatcct tcaccaacaa ttactccaat aggtccgact acaactaagg caatacagct
    51121 tgatactaat aatactagcg taggttgcaa aaaactctta gtaatagcta gtgttaattt
    51181 agcaattatt ttttcaatat atttcatcaa ccaaaccata ataagaattg gaacgactga
    51241 tgaaccataa ctagctggtg tcacaggtgc accaaataaa ctaagaggat tccctgattg
    51301 caccatttga acaaaatttg gatggagaag tacacctgct acagacatag ctaatgtaga
    51361 tgttactttt aatttttgtg atgcagaata agctaataac agcggtaaga aataatatgg
    51421 agcatcccca aaaaatgtca aaaaagcaat agtctgagaa tctgattgca atataccaag
    51481 cattggtaaa atgattacca agactttcaa catacctccc cctaacattg ctggaatgat
    51541 tggagtcatg gaaccagcga tatactcaat gattctttct aaaatattcc ctttgtgccc
    51601 ttgaacaact gaatcggatt caaaattgcc aagtttaacg aattctttat aataattagc
    51661 tacatcatta ccaagtataa tttgatattg tccattcttt ttcataatac ctattacacc
    51721 tggtatcttc ttcacatcat catcattgac taaattttca tcttttaatt ctaatcttaa
    51781 acgtgttaca caatgggtaa ctctattgac atttttttca cctccaatta catcgaggat
    51841 tttttgtacc gtatctttat aactcatggt attctcctat tctattaatc taaatttttt
    51901 gttaagcgac gaatatgagc catcaaataa gctaattcac tagaagtcag caaataattg
    51961 tactccgttt gtataaacat tgctacctgt tcaccacatt catattctct aggatattta
    52021 tttttcatta atgctaacaa gtcttcatca tcatcgtcac aataagttgt attttcaacc
    52081 aagcgatggg caaataattt tatatgagtt atgaatctat aataatcaat agaatcttgg
    52141 ttaaactcag tacaatagaa atcttgaatg attttctcaa ttcccataat tatttcagtg
    52201 attttatacg actcttgaaa attattttct aaattagcat taacaaaatg tagcgctatg
    52261 aatgcagctt cgtcaattgg aagttcaata cctaactctt tttttattat ttgtaaagcc
    52321 cttttcccaa gttcaaattc ttctttataa tatttcgata tttcccagcg taggggattc
    52381 gaaataataa tcccttcttt ataacgttct atgctcgaag aaatatgatc cgttaaatta
    52441 atatagataa tttcatcaaa attattaccc aatgttattt tacctaggtt aattattttt
    52501 tcggtgatgt acaccaactc caaaggaacg ttaataaaca tctctgtaaa acgggtcata
    52561 ttatctctat ttttgagaaa aaaacttttc tcaatatcaa ttggatttac tttatctcca
    52621 gtttttcttc caaaagctat tccccttcca aaaagaagaa tatcgatatc ttttttactt
    52681 tgcgcaatta cggcattgtg gtttagtatt cgttttatga tcataaaatt tcccttttaa
    52741 aataaaagga acctacttaa aaacatcaag aaacttcttc tgatgtgatt aaataggttc
    52801 ctgctcactt gtattagtga taacatcctt ttatttcaat ttttaatggt gacatgaagc
    52861 ttaaataatt aataactctg taaccgtttt tattttatga tatttcaatc tatttgtcaa
    52921 gtacttataa aaattttttt attttgtgtg attcgaatgt gataatggca acagtctcac
    52981 taaagaaatg aaaatcatac atagaaattt ttaaaaattt tctctatcgt aaacctgcca
    53041 ctagttcaga aactatacta gctgattcca aacgtaatat ggtcatctca tctaccttcc
    53101 ctaataatgg cattgcacca taccaaacaa tagtcttatt caccaaaaga ataggcgtta
    53161 ctatttttga ttgagtaaaa gacactttaa ttttctggct cttcaactgg tctagccatg
    53221 ctttatttgc aaccgtctct ggtatacata tctcaatttg actaatccta aattctttta
    53281 gaaaattcat cagttttgtc tggtgcacat aaggtaaaat aagcagacat tcctgtcttt
    53341 cccctgctaa gtcctctctc aacaccttct catatctact atcaacataa acgaattgtt
    53401 tctcctcacc ctcaatggca cgataatcca tctttcgata agctacttgt cgtttctgaa
    53461 acatcttttc taaataagga acatgaatat ccacataatc gaaaatacgc accaaagact
    53521 tatccttgta gtttctatga atccaacctg catactgaat caaattattt ttccaagaaa
    53581 agggtgctgc caagataagc gtgtccaact gaggtaagtc aaaaccttcg ccaatgtatt
    53641 ttccagtaga caacaaaaca aaccctttat ctaactgttc taacgtctcc agtaaactcg
    53701 ttctctctcg gactttggtt tttccgctaa taatgtaaca gtcatcaacc tctttctctt
    53761 tcaataattt ttcaaagaca tctatctgtt gaattcgatt aactaaaacc aagatattcc
    53821 gtccttctgc cacttgggct agaatatcct tgagaatcat ctgattcctc actgagtcag
    53881 tagcaatcca atcactaagc tgtataaaat tacttgcttt ggtcttttca atttccaaat
    53941 gaccaaaaga agtgaatctt aattgcaatt gccgtttaaa atccgtttcc ctcttatcag
    54001 cagtatggag tatctcacca attctctgaa aaacaatagg ctcatgacca ttcttacgct
    54061 caggcgtagc cgtcaaaccg taaagatact tccctctaaa ctgagcaaca actttttcaa
    54121 acatcaaggc agagacatga tgacactcat ccacaatcat catctcatac tcatccaaaa
    54181 gactttgact attttccaac ttaaatagag attgaatcat aacgacatca accagtttac
    54241 tcagccattt cttagtccca ccgtactgcc caacatagcc gattaccttt tcacgacctg
    54301 atgccgtata acggatagcc tcctcctctt cgaaagtcaa aaagcagttt aagcgatcta
    54361 gccattggtc taagagttgc ttattatgga ctagaataat tgtttttgtt ttccgttcag
    54421 agataagagc agcacctaaa acggtcttcc caaaaccagt ctccgcatga agtaaaccat
    54481 tttctttaga agtcatatct gacagggcta actcttgctc aaaagtgagt tctcccttaa
    54541 attccacgct aatagacctt tgtacctttc tcctatcttc cacagatacc tgcttaaatt
    54601 tatcttgcaa tggatacagc aaacctcttg gcaaccataa ataatgatcg gattctccaa
    54661 ataaatacat tctctcagga atttgatagg ttggctgtcg catagcctgc tttaaatata
    54721 gtaaaatgaa ataataacag gacaaatcga tcaggaaagt caaatcgatt tctaacaatg
    54781 ttttagaagc agaggtgtac tattctagtt tcaatctact ataaaattcg ggattagaaa
    54841 aggaagccat atttttcaag aaaaaagtgc cttggatgtc acagacgatt tttcaagttg
    54901 gatcatattg gataaaacga ccttcaactc cttatccaat tcttgcttgc ctaactcctc
    54961 ttggattaac agtgccactt tagcagttga aatcctctga atttcttgta gatacctcca
    55021 ttggtcttca taaggctgaa actgttcatc cacaaagacc gttcgccctt gatggtaagc
    55081 ttctccttga aaaggcaagg caatcaaatt tccaaatccc cccttaggaa ggacatcctg
    55141 atttggaaac atgcgatcaa aagaatcaaa ggacagttgc atactttcct gcattgccaa
    55201 ttctaatagt ttctttccaa acaggcgagc ctttcgactc agaatcgctt cctcaaagaa
    55261 gaaccaaata tggagtccgt aacccgaacg agaaatctct aaatgggctt ccatctggcg
    55321 ttccctggct attcttcgaa tggttaaacc agcttctttc caatctcctt catccaaatc
    55381 cagtaccaaa aaataacagc tatcatctaa gtgcatagga aagataccga tagctgcctc
    55441 cccacgaaaa tgagatttca aaacggaatc cgtcaatgtc tggaaactcc gtttttcagg
    55501 tagcaactgc ttccaaccat aatcatagga aggaaaatac tgaattttcc cttgatcatt
    55561 gataaaactc ttagcataaa catcataacg gccagcaaac acagaggtaa acaattgtaa
    55621 tttttcttgc gtcgtcaagc gactactttg aagttggaac atctcctcga actgagagcg
    55681 ttccataaca aactgactct tgtctttaag acgtttacac aagaaaaact cactatcccc
    55741 atcaaaagaa gaaaagacat caagtacttc taccacaatt ccatccaaag acacaaaaac
    55801 agccataaga gtcacctcct tgattcctat aggctgatta taacaagaat agctgaaatt
    55861 gtacacgaaa ataaaatccc ttatttgtta caataccttt gaaaactttt atttctttgc
    55921 tacccagccg atggcatcgc ttgggggatt ttcggtatca atccagataa attcaatacc
    55981 gatttcccca tttttaaatt tagttaaacg aataccgttg atttccagtt cattgagtcg
    56041 ttgacctgtc aagacttctc gttctttcaa ctggaaaagt taagggggga actaatacaa
    56101 atcttctaag cttctatatt caatgatttc atttttgata atattctttt taaactcaaa
    56161 atgttttaaa ggattatcga ttaacactaa ctttggaata tcatctagat ttgtgaccaa
    56221 ggataaaata aaatccgatt gaaactcctt gactttttca aattcttttg cagttaaacg
    56281 cacacgcccc ttagattttc ggataccttt tacttcggca aggtaagaat actcttggac
    56341 atctacctga aagtcatatc catcaccata aagacgggca tcggttaact gtccaccttg
    56401 gaatttttct tctttatcaa aatgaaggat aaaataattc tcagcctcca ttcccgtttc
    56461 ctgtagacgt ttgaatttag ttcgaactat tggtttttca acgatggtta tgcctgtttt
    56521 cttcccttca ctggcaagta acattttaac tatttcagca taactatgaa catcttcatt
    56581 tccaaacatc atatcaatta aatctttacg aaaacgataa acttcagctt tctgccacca
    56641 accttttcga ttattgtcaa aataaggatc aaataaatcc attctatttt ttacaactcc
    56701 agttgtttca gcaattccca gagaaaccac ataacgataa aactccgact tgctagagca
    56761 ttgaaattct tttataaaaa gcttgtcaaa cttggcaaga ccgtagccaa ttaaatttaa
    56821 caattcataa tgagggtgtt tggacatcac tttctccatc aatagatatt gatttcatta
    56881 taccaaaaaa acacggctca tcaccgtgtt tctgtgttta tttaacgagt ttcttcatct
    56941 catcaatacg tgctacggtc gcatcatact tggcttggta gtcagcttgt ttgtcgcgtt
    57001 ctttttggac gacttctggt ttggcgttgg ctacgaagcg ttcgttagag agtttcttac
    57061 caaccatgtc cagttctttt tgccatttag cgagttcttt gtcgagacga tctagttctt
    57121 cttcaacatt gaggagatcg gccagtggca ggtagatttc tgctcctgtg atgacacttg
    57181 acatagccag ttcaggtgca gggatggttg atgcgatttc caaatgttct ggatttgtaa
    57241 agcgtttgat gtagttgaca ttgctgttaa agaaggcttc caagtcacta tcgctagtct
    57301 taacaaggat tgtaataggt ttgcttggtg ctacatttac ttccgcacgc gcattacgaa
    57361 cggcacggat caagtctttg agactttcta caccagtgtg agccgcaagg tcttcaaagg
    57421 ctagattaac agttgggtat gcagctgtca cgatagaacc ttctgagatt tgtccaaaga
    57481 tttcctctgt cacgaatggc atgattgggt gaaggagacg aaggatcttg tccagagtgt
    57541 aaaggagaac agatcgagta attaccttat cttcttcatt atcgctataa aggacttcct
    57601 tggtcaactc aacataccag tccgcaaatt catcccagat gaagttgtag aggatgtggc
    57661 cagcaacacc aaactcaaac ttatcaaagt tagcagttgc ttttccaatc gtttcattga
    57721 ggttgtggag aatccagcgg tccgtcacat taccagcctc acctgttgca acttttgtga
    57781 cattgtcatg cgccacatcc agcgtcaaac ctccattgtt catgaggata tagcgagaaa
    57841 tgttccaaat cttgttaata aagttccatg aagcatccat tttctcataa gagaaacgca
    57901 cgtcttgtcc tggcgcagaa ccgtttgaaa ggaaccatcg aagggcatcg gcaccgtatt
    57961 tctcgataac atccattggg tcaatcccgt taccgagaga cttagacatc ttgcgtcctt
    58021 gctcgtcacg aataagaccg tggataagga cgttttggaa tggttgacgg cctgtgaatt
    58081 ccaatgactg gaagatcata cgagacaccc agaagaagat gatgtcgtaa cctgttacca
    58141 aggttgaagt tgggaaataa cgtttaaagt cttctgagtc gacttcaggc cagcccatgg
    58201 ttgaaaatgg ccagagggca gaactgaacc aagtatccaa gacgtcttcg tcctgagtcc
    58261 atccgtcacc ttctggagct tcttcgccga catacatttc accatcagca ttgtaccagg
    58321 cagggatttg gtgaccccac caaagctgac gagagataac ccagtcgtgg acattttcca
    58381 tccattgaag gaaggtatcg ttgaaacgag gtgggtagaa ttcgaccttg tcctctgtgt
    58441 cttggttggc aatggcgttc ttagccaatt ggtccatctt gacgaaccat tgagtagaca
    58501 agcgtggctc aactacgaca cctgtacgtt ctgagtgacc aacactgtgg acacgttttt
    58561 cgattttgac aagggcaccg atttcttcca acttagcaac gactgcctta cgagcttcaa
    58621 aacgatccat gcctgaaaat tcaaaggcaa gctcattcat agttccgtcg tcgttcatga
    58681 cgttgacttg tggcaagtta tgacgttggc caaccaagaa gtcatttgga tcgtgggcag
    58741 gtgtgatttt cacgacacca gtaccaaact caggatctgc gtgctcatct ccaacgattg
    58801 ggatgagttt attagcgatt ggaaggatga cgtttttacc aatcaagtcc ttgtagcgcg
    58861 ggtcttctgg attaaccgca accgcaacgt ccccaaacat agtctcagga cgagttgtag
    58921 caacttcaag ggcgcgtgaa ccatcttcca gcatgtaatt catgtggtag aaggcacctt
    58981 ccacatcctt gtgaatcacc tcaatatcag aaagggctgt gcgagctgct gggtcccagt
    59041 tgatgataaa ctcaccacgg tagatccagc ctttcttgta aaggttcaca aagaccttac
    59101 gaacagcttt tgacaaacct tcgtcaagag tgaaacgctc acgagaatag tctacagaga
    59161 gccccatctt gccccattgt tccttgatgg tagtggcata ttcgtctttc cattcccaga
    59221 ctttcgtcaa gaaagactca cgaccaaggt catagcggga aatgccctca ccacgcaagc
    59281 gctcctcaac cttagcctga gtggcaatcc ctgcgtggtc catcccagga agccaaaggg
    59341 tatcaaaacc ttgcatgcgt ttttgacgga tgataatatc ttgcaaagtt gtatcccaag
    59401 cgtgaccaag gtgaagttta cctgtaacgt ttggtggtgg aataacgatt gaataaggct
    59461 tagccttttg atcgcctgaa ggcttgaaaa catcggcatc aagccatttt tggtaacgac
    59521 cagcctcaac ctcggctgga ttgtatttag atgaaagttc tttagacatg tgtgttctcc
    59581 ttaattactt ttattgacaa ttttaaccaa accaattttt gaaagttcaa tataaatctc
    59641 ttcaatttca gcaaatgctg caagtggtga catagtataa tttccaggat tatatttaag
    59701 atcatacttg cttatctttg aaatataata cctagagtgt ttcaatttta atgattccaa
    59761 ctttgattta atatctacta atgtattatg gtttaacttt aaaaacaact tattataatt
    59821 accatagagc tctgtaagag cattaaagta ttctttcact agagctatag cgtcaatctt
    59881 agatgtttct tggtttagtt ttatcaactc ccctttcaat tttttccatt taaagttgga
    59941 atttaaaaga taatctaaat caatatagaa atctattata acagtctcat catctgggct
    60001 aacagctttt acctcattta ttggtaagtc agtatgttgc gaataatttc tcaaagaatg
    60061 gcaaaatcga taagcaaaat tggtatcata ctgatagctt gcaaaaccat gtatacaatc
    60121 aaactcctca ctatctttgg aatatttttg tttaatttgg ttttcgttaa aatcgacaaa
    60181 caattttcca ctggataata aatgaatcat gaaacgattt acatctgcct cttcaatttc
    60241 taattccttt gactcaagtt tatttttaat acttaaaaaa tccgagacat ctgaaataaa
    60301 caattcgaac atattcttga ttttttgaaa attcttttga atctcaaaaa tttggtccga
    60361 tactgacatt atttccttgg ttggttcaat atcagagatg acaatacgtt tttcattgtt
    60421 gttaatttct aaataagcta atcgctcgat aatatcacta tcatttaatt cagcatactc
    60481 aacatcaatt tggcgtaact gcttctcaga tagagagctt acttcctctt ttacatcgct
    60541 catcttattc ctcccactcg ctcttcagca agccatatat cagactgtca cagcggtttc
    60601 cttgaacatc ctttcggtct cttatgcgag cttcgagggt aaagccaagc ttttccgaga
    60661 ctcgttgact ttgaaggtta tatccaaagc aagttagttc aatcttgtga agaccaagtt
    60721 ctttaaaagc tagatcaatc aaggcacacg ctgcttctgg aacataacct cgcccccaat
    60781 agtctgggtg taaggtatag ccgatttcca gcacatcatc ttcatggcga tggttgaaat
    60841 cgacagagcc aacgatctta tccgttcctt tgacgacaat cccgtagcct gctgggagat
    60901 tttccttttg attacgctcc ggaagaatgt gctccagata ataaatctca tcttccaagg
    60961 tcttgactgg aggaaaacct gctggatagg caacctctgg caaactagca tagtcaaaga
    61021 tatcctcagc atccgccaca gtacggactc gtaaaacgag acgttctgtt tcgattttat
    61081 ctggcagctc agttcttgcc atccttcttc ctcgcttttt tgatgaaact gcccttcata
    61141 tctacacgct tgtccagata gcgataaacg cgctgatatc catctcccat gaaataggtt
    61201 ggggcaaaca gttgattttt aaaatgtccc ttttcatcca ggagttctgg aacaacaagt
    61261 cgctcaagaa tcttggcaaa gatgtggcaa ataccgtctt cctcaacaat cctatctacc
    61321 cgacaatcta aaacaagtgg acaggcgtct aaaataggag tctgagttca ttcagaaatt
    61381 tcataatgca ctcccaaacg ttccaatttc tcctgatgac tgataaaacc agcctgctcc
    61441 atcgcaagca tagaagtttc atcagaaata ttcacagtaa atttttgata ctgtttgatc
    61501 tgctctgcgg cattctctct tgcaacgact ccaatcacaa cccaatctcc tagactataa
    61561 gaggaactac aggtcgtgat gttatagcca aaattctaat cttgatatcc taaaataaaa
    61621 acaggaaaac cataatatag tttacttgtg ttaaaagatt gcttcataac aacccccttt
    61681 gactaagacg taaaagaaaa gccctgccat ctacatgaca gggacgaatg tgtttatccg
    61741 cggtaccacc caatttcggg cagttgcccg caactctcgt ctttaaagca aaaagacact
    61801 tttatttcaa tttttcatcc attagcaacc agttttgaca catttgtgga cttctcagcg
    61861 ccgccacttt ctgtaaaatg tgggattcaa aacacctcta atggctctat tgtagcaaga
    61921 ttttttcgga aatgcaaggc tcaagaaaaa ttacttgaac ttgatgccat tttctttcaa
    61981 tttcttgatg gtagctgggc cgattccttt caaggcaagg agttcttttt cagtccagtt
    62041 tttgaaatct gaagcagact tgattccttc atcatagaaa gtcttggcac gatcaagtgg
    62101 aagtccaccc aaatttgctg caaaatcttc tacagaatta gctacttttt gagcttgctc
    62161 tttggtagct tctactgctt gttcaacttt tttagaaaca gccttaccag ctgcgcttgc
    62221 tgactgttct gcacgcttca cgactttttt tgtctcatct acaaccttag tcacagtact
    62281 tgaaaaggca cctgcgcgac ggaggccatt tcgtaattgt tttttacgat tgagtttctt
    62341 tgacatgata aaatcctttc aataaaaaat ccctgctctg acaaggattt aacataaaca
    62401 ttctatcaag attttagtga aaaatcaaga atctttctcg tttaataatt tcgctcacca
    62461 aacaagcctt ctggcaaatc atggaatccc ttgcctgctt tgaagttttc aaacttacca
    62521 agcaagaact gataagcatc caagcgactc tcgtagcgaa tcatggcatc tttggcacgc
    62581 tcgtcctggt cttcttcgta aactttttga ctttccttgt gcgccatatc gttaatcatg
    62641 atttgggtat tgacccaagc ttcaaattcc ttcataaatt cttgttcgta actcattttt
    62701 tctccttatt ctaatccacg aaaatagtcc gtatcaatct cacggtaggg ctggatatcc
    62761 tgaacatact ccaacactcc ttggaattct ccgtcttcat cgtgtactgc agcataggtg
    62821 atgtggacaa acttacctcg cgactcagac ttgaaccaca tttcatactt gtctttgctt
    62881 ccctcacgaa gccccttcat gatagttttg accttgtcca agtacttagg cggatggcag
    62941 agttcgacat tgcgcccgac ttgggacggc gtccgtttga aaatcatctc atcagctggc
    63001 gtattgtcat tgtaatactg gaaaatatct tctttattga caaaggtaat ctccataggg
    63061 agatgattga ggatgagatt ggcctgctcg actgaaagat agccattacc aaaagcctgt
    63121 tgactatggc ggtccagcac agcttccttt tccttagggg taaaggtaat ggtaaaatgg
    63181 ccttctggcg tatctatgac ttgttgaact tgaccttctg ccgtatctag ctgtacaggc
    63241 tcctctgcaa tcttttcctc aataaagctc tgtcgttctg gcacccattt ctctgacgga
    63301 cggatgatgg catagccata ggcatcgctc tcctccgcaa tctgaagcca gtcatcctga
    63361 gtaaaagact caaggagaat catgaggagg atggactctt ccttgaaaat catactttca
    63421 aactctgtcg caaaagcttc aaaagcttcc tttacactgc taattgacac ttctggtagt
    63481 gacttggctg tcgttagagc tgtttgaaag agttccctaa tctgatcatc cactccccac
    63541 ataactttgg gaggtgaatc gtgtccatag cgctccatga taggaaagaa gagttcttcc
    63601 ttacgttggt aatggatgtc aaattgaccc acaagtccca tctgacgcac caaaccctta
    63661 cgcatctccg ccagcatttc ctcgtcttcc atagactcat aggtatctaa caatctacga
    63721 atgcgaatca aggccgcacg gagagccaga ttttcttctt tgaagacacg aactgggtga
    63781 cctggatgct cagtatctga aacttcgaca cctttgatag catttttaaa aagattggca
    63841 tggacatcac agagttccat aacatcttca aaagtgacgc ccgaatccga gttcatcagc
    63901 tcgtgctcca taagggaaat ctcgatggct gacacgcccg taaaggtcgc atcaaagcga
    63961 tcttgaaccg actcaggaga ggcgccattg tgcaattcta acaaaatatc ccgtaggata
    64021 tgaatccgtt catctgtcat tagtctaatc caatcacttc gtagccattc gcttccagtg
    64081 tgcgtacaat cttgtccata ggagttcctg ctagcttaga accctgttta agtgatactt
    64141 tacgaccaac tgtattgcgc attaagggat tggcaagggg tttaaaaccc aactccacta
    64201 gaatttccaa gacttctgga tgcttgtcca ccacttctgc aacaggaatt gacacatcga
    64261 tgatattgtc catgacgacc tccattgtat gttctaatac tcaatgaaaa tcaaagagca
    64321 aactaggaag ctagccgcag gttgctcaaa acagtgtttt gaggttgtag atagaactga
    64381 cgaagtcagc tcaaaacacc gttttgaggt tgtggataga actgacgaag tcagtaacat
    64441 atatactgca aggtgaagct gacgtggttt gaagagattt tcgaagagta taaaatgatt
    64501 ttactgctta tattatacca tatggaaaga gaataaaaaa ctagcagtgg agttcctgct
    64561 agttctctgc aacttggatt accatctaga taagtttaaa gaaccaatcc aatatcttgt
    64621 aaaacagcaa ttgaactgca aaagaaatga tcatccaaaa gaatttcaca atcccaataa
    64681 tcggtttgat aaaaagaata gcaagaagac caaaaaaatt tcattctctc tcctctggct
    64741 taatgagcca ccgagccgta tccattagct tatctgcaat aaaaagtttg cccagaccaa
    64801 caacgacatg gtcagctttc tttatcgttt tcatcacttt tacaccttgc acggtcaaaa
    64861 agtaattacc ataaatttta gcaaaagctt tgataggatt catattactc tcctttgatg
    64921 atttcagcct cttttcggat tgtttcaaca tcttcttgat attgaacttc actatagttg
    64981 actagcttgg ataattcttt ctgcaagctt tcccccattg gtttcatagt tgcaaaggtt
    65041 aaaccacctg aaatgatacc acccaagata ggaataaatt tccctattcc tttggccagc
    65101 cctcccttgg taagattcac accaaatatt tttaagactt ttttcaaaat agggtaccaa
    65161 agcgtctttg ttaaagcttt attaggcact gttttcatta cctgtttggc aattgttata
    65221 ccaccagcac gtagcaaagc agcggttcca ttcaccccta acattacgcc tagataaagc
    65281 aagagggtat tttgagcatc ttcactcaac tcctcgcgtg aagcccaaag atcctcataa
    65341 ccataaatat aacctaattc ttgagccaat ttcagagaga aagcataaaa ttgagccaca
    65401 tcagctggaa tggtaattgc catagcaagc cctccaggta atcctgccaa aacagaagtc
    65461 ccactcgcta ataatacatt gtcccgaata caagcattag ctacacgatc taatatttct
    65521 tgagatagaa gagtcgttgg gtcttgttcc aataaggtag gaatatcttt tggatccaat
    65581 tctttggaaa acttatccac taaaaatttc gaacgatcaa ccttaacaac aggtagtttc
    65641 accacttgtt gcaatacttg catagctaag tcttgttcag ccatatacaa actccttatt
    65701 tcttttttgc accttatcat attatatttc ctacaaaaaa agcattttct aattagataa
    65761 cattaaaaaa tacagaaccc ctttt
//
LOCUS       DAVHKZ010000005        64654 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000005 DAVHKZ010000000
VERSION     DAVHKZ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64654
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.005"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            1..133
                     /locus_tag="VVO74_000452"
                     /pseudo
     CDS             1..133
                     /locus_tag="VVO74_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            136..1149
                     /locus_tag="VVO74_000453"
                     /pseudo
     CDS             136..1149
                     /locus_tag="VVO74_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            1124..1702
                     /locus_tag="VVO74_000454"
     CDS             1124..1702
                     /locus_tag="VVO74_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HEU5694534.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKT
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSTAHYGRVETAISFLPSSMETKPTDESGT"
     gene            complement(1759..2043)
                     /locus_tag="VVO74_000455"
     CDS             complement(1759..2043)
                     /locus_tag="VVO74_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU5694535.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(2097..3032)
                     /locus_tag="VVO74_000456"
     CDS             complement(2097..3032)
                     /locus_tag="VVO74_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU5694536.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3136..3579
                     /locus_tag="VVO74_000457"
     CDS             3136..3579
                     /locus_tag="VVO74_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU5694537.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            3695..3961
                     /locus_tag="VVO74_000458"
     CDS             3695..3961
                     /locus_tag="VVO74_000458"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU5694538.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            3958..4332
                     /gene="crcB"
                     /locus_tag="VVO74_000459"
     CDS             3958..4332
                     /gene="crcB"
                     /locus_tag="VVO74_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU5694539.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            4326..4655
                     /gene="crcB"
                     /locus_tag="VVO74_000460"
     CDS             4326..4655
                     /gene="crcB"
                     /locus_tag="VVO74_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU5694540.1"
                     /translation="MVIVYLAIACGFGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            4774..5121
                     /gene="rplS"
                     /locus_tag="VVO74_000461"
     CDS             4774..5121
                     /gene="rplS"
                     /locus_tag="VVO74_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU5694541.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            5163..5234
                     /locus_tag="VVO74_000462"
     tRNA            5163..5234
                     /locus_tag="VVO74_000462"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5196..5198,aa:Arg,seq:cct)
     gene            complement(5289..6095)
                     /gene="yidA"
                     /locus_tag="VVO74_000463"
     CDS             complement(5289..6095)
                     /gene="yidA"
                     /locus_tag="VVO74_000463"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU5694542.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETDTGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTLVL"
     gene            complement(6108..7412)
                     /locus_tag="VVO74_000464"
     CDS             complement(6108..7412)
                     /locus_tag="VVO74_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU5694543.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            7484..7861
                     /locus_tag="VVO74_000465"
     CDS             7484..7861
                     /locus_tag="VVO74_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU5694544.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            7952..8284
                     /locus_tag="VVO74_000466"
     CDS             7952..8284
                     /locus_tag="VVO74_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU5694545.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            8296..9867
                     /gene="ffh"
                     /locus_tag="VVO74_000467"
     CDS             8296..9867
                     /gene="ffh"
                     /locus_tag="VVO74_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU5694546.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKVLAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(10062..11345)
                     /locus_tag="VVO74_000468"
     CDS             complement(10062..11345)
                     /locus_tag="VVO74_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU5694547.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMLATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(11599..12312)
                     /gene="rsmG"
                     /locus_tag="VVO74_000469"
     CDS             complement(11599..12312)
                     /gene="rsmG"
                     /locus_tag="VVO74_000469"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU5694548.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12406..12966
                     /locus_tag="VVO74_000470"
     CDS             12406..12966
                     /locus_tag="VVO74_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU5694549.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            12968..13867
                     /gene="htpX"
                     /locus_tag="VVO74_000471"
     CDS             12968..13867
                     /gene="htpX"
                     /locus_tag="VVO74_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU5694550.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(13911..15470)
                     /locus_tag="VVO74_000472"
     CDS             complement(13911..15470)
                     /locus_tag="VVO74_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU5694551.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLSKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIHSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(15709..16026)
                     /locus_tag="VVO74_000473"
     CDS             complement(15709..16026)
                     /locus_tag="VVO74_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU5694552.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FEF"
     gene            16196..16738
                     /locus_tag="VVO74_000474"
     CDS             16196..16738
                     /locus_tag="VVO74_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU5694553.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16738..17367
                     /gene="nth"
                     /locus_tag="VVO74_000475"
     CDS             16738..17367
                     /gene="nth"
                     /locus_tag="VVO74_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU5694554.1"
                     /translation="MVLSKKRARKVLEEIITLFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            17578..18099
                     /gene="pyrR"
                     /locus_tag="VVO74_000476"
     CDS             17578..18099
                     /gene="pyrR"
                     /locus_tag="VVO74_000476"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU5694555.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            18118..19041
                     /locus_tag="VVO74_000477"
     CDS             18118..19041
                     /locus_tag="VVO74_000477"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU5694556.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            19091..20170
                     /gene="carA"
                     /locus_tag="VVO74_000478"
     CDS             19091..20170
                     /gene="carA"
                     /locus_tag="VVO74_000478"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU5694557.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            20483..23659
                     /gene="carB"
                     /locus_tag="VVO74_000479"
     CDS             20483..23659
                     /gene="carB"
                     /locus_tag="VVO74_000479"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU5694558.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(23934..24743)
                     /locus_tag="VVO74_000480"
     CDS             complement(23934..24743)
                     /locus_tag="VVO74_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU5694559.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(24745..25548)
                     /locus_tag="VVO74_000481"
     CDS             complement(24745..25548)
                     /locus_tag="VVO74_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU5694560.1"
                     /translation="MKQLTVEDAKQIELEILNYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(25558..27045)
                     /gene="tacF"
                     /locus_tag="VVO74_000482"
     CDS             complement(25558..27045)
                     /gene="tacF"
                     /locus_tag="VVO74_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU5694561.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFMYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            27381..28088
                     /locus_tag="VVO74_000483"
     CDS             27381..28088
                     /locus_tag="VVO74_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU5694562.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLHKERIIITKGGADRNTSIEKIIEAIDAYRPL
                     TSEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            28093..29115
                     /locus_tag="VVO74_000484"
     CDS             28093..29115
                     /locus_tag="VVO74_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU5694563.1"
                     /translation="MINQIYQLTKPKFINVKYQEEVIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            29132..30001
                     /gene="licA"
                     /locus_tag="VVO74_000485"
     CDS             29132..30001
                     /gene="licA"
                     /locus_tag="VVO74_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU5694564.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIEFAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            29991..30869
                     /locus_tag="VVO74_000486"
     CDS             29991..30869
                     /locus_tag="VVO74_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU5694565.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            30881..31570
                     /locus_tag="VVO74_000487"
     CDS             30881..31570
                     /locus_tag="VVO74_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEU5694566.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEIFKNEN"
     gene            31666..32514
                     /gene="dprA"
                     /locus_tag="VVO74_000488"
     CDS             31666..32514
                     /gene="dprA"
                     /locus_tag="VVO74_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU5694567.1"
                     /translation="MKITNYEIYKLKKSSLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPDSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            33398..34441
                     /locus_tag="VVO74_000489"
     CDS             33398..34441
                     /locus_tag="VVO74_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEU5694568.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            34608..36695
                     /gene="topA"
                     /locus_tag="VVO74_000490"
     CDS             34608..36695
                     /gene="topA"
                     /locus_tag="VVO74_000490"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU5694569.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            36801..37160
                     /locus_tag="VVO74_000491"
     CDS             36801..37160
                     /locus_tag="VVO74_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU5694570.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            37253..37885
                     /locus_tag="VVO74_000492"
     CDS             37253..37885
                     /locus_tag="VVO74_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU5694571.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            37929..38585
                     /locus_tag="VVO74_000493"
     CDS             37929..38585
                     /locus_tag="VVO74_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU5694572.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            38604..39698
                     /locus_tag="VVO74_000494"
     CDS             38604..39698
                     /locus_tag="VVO74_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEU5694573.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTPEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGIAVANSLAAVKNGAGRVEETINGIRERAGNAALEEIAVALNIRQDYYQ
                     VETSIVLTETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQERVLVTVENRDTETILNAAGLDFDVLKASA
                     IAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            39710..40747
                     /gene="leuB"
                     /locus_tag="VVO74_000495"
     CDS             39710..40747
                     /gene="leuB"
                     /locus_tag="VVO74_000495"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEU5694574.1"
                     /translation="MAKKIVALAGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGSPLPDETLKASREADAILLVAIGSPQYDGVAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPISMILLVVMMLRDSFGRYEDTERIKRAVETSLAAGILTRDIGGQAST
                     KEMMEAIIARL"
     gene            40744..41013
                     /locus_tag="VVO74_000496"
     CDS             40744..41013
                     /locus_tag="VVO74_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU5694575.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            41017..41376
                     /gene="leuD"
                     /locus_tag="VVO74_000497"
     CDS             41017..41376
                     /gene="leuD"
                     /locus_tag="VVO74_000497"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU5694576.1"
                     /translation="MVGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSKWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            41538..42161
                     /locus_tag="VVO74_000498"
                     /pseudo
     CDS             41538..42161
                     /locus_tag="VVO74_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            42327..44258
                     /locus_tag="VVO74_000499"
     CDS             42327..44258
                     /locus_tag="VVO74_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEU5694577.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGRQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            44245..45561
                     /locus_tag="VVO74_000500"
     CDS             44245..45561
                     /locus_tag="VVO74_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU5694578.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYQRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            45736..46722
                     /locus_tag="VVO74_000501"
     CDS             45736..46722
                     /locus_tag="VVO74_000501"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU5694579.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVSQLKADTPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            46786..46857
                     /locus_tag="VVO74_000502"
     tRNA            46786..46857
                     /locus_tag="VVO74_000502"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46819..46821,aa:Arg,seq:ccg)
     gene            47040..47738
                     /locus_tag="VVO74_000503"
     CDS             47040..47738
                     /locus_tag="VVO74_000503"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU5694580.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            47729..51268
                     /gene="smc"
                     /locus_tag="VVO74_000504"
     CDS             47729..51268
                     /gene="smc"
                     /locus_tag="VVO74_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU5694581.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENACKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIVIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMAALTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQESLATIASEKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEEVAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            51265..52059
                     /locus_tag="VVO74_000505"
     CDS             51265..52059
                     /locus_tag="VVO74_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU5694582.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            52059..52877
                     /locus_tag="VVO74_000506"
     CDS             52059..52877
                     /locus_tag="VVO74_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU5694583.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVSEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            52881..54158
                     /gene="ftsY"
                     /locus_tag="VVO74_000507"
     CDS             52881..54158
                     /gene="ftsY"
                     /locus_tag="VVO74_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU5694584.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEAERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(54202..55689)
                     /locus_tag="VVO74_000508"
     CDS             complement(54202..55689)
                     /locus_tag="VVO74_000508"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU5694585.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFDAKWTWQPDIAYRQDGRFE"
     gene            complement(55838..56578)
                     /locus_tag="VVO74_000509"
     CDS             complement(55838..56578)
                     /locus_tag="VVO74_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU5694586.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(56578..58743)
                     /locus_tag="VVO74_000510"
     CDS             complement(56578..58743)
                     /locus_tag="VVO74_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU5694587.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            58916..59869
                     /locus_tag="VVO74_000511"
     CDS             58916..59869
                     /locus_tag="VVO74_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5694588.1"
                     /translation="MKNKRIFKDFQASKMNLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            59946..61934
                     /gene="uvrB"
                     /locus_tag="VVO74_000512"
     CDS             59946..61934
                     /gene="uvrB"
                     /locus_tag="VVO74_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU5694589.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            61944..62507
                     /locus_tag="VVO74_000513"
     CDS             61944..62507
                     /locus_tag="VVO74_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5694590.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKMNDGYYQINGNS"
     gene            62473..62982
                     /locus_tag="VVO74_000514"
     CDS             62473..62982
                     /locus_tag="VVO74_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5694591.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SKIILKSRS"
     gene            63035..63502
                     /locus_tag="VVO74_000515"
     CDS             63035..63502
                     /locus_tag="VVO74_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU5694592.1"
                     /translation="MSRSQLTILTNICLIEDLETQCVVMQYRAPETNRWSGYAFPGGH
                     VENGEAFAESVIREIYEETGLTIQNPQLVGVKNWPLDTGGRYIVFCYKATEFTGTLQS
                     SDEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(63499..64014)
                     /locus_tag="VVO74_000516"
     CDS             complement(63499..64014)
                     /locus_tag="VVO74_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU5694593.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHQVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(64026..64553)
                     /locus_tag="VVO74_000517"
     CDS             complement(64026..64553)
                     /locus_tag="VVO74_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU5694594.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
BASE COUNT        19642 a        11696 c        14234 g        19082 t
ORIGIN      
        1 ccacgtccag aacatcctag gaaagcagac gctcaaacca ttgtcgcgtc taaaaataaa
       61 atctcaattc aagaagaaaa gaaagcgctt taaaaccagt agaccttttc ataaggttcg
      121 cttgatgtac caaatagtac gcccatgcaa aagaatatct attttgttgt cttggacctg
      181 catacgacgg atagagataa aattatccag ctattcaagg attggacgga ttatagtgcc
      241 aagttggtcg agggggaatt ggttaaaaaa gatggacaga atgctctctt tcctccgagc
      301 gatactggtg agacagttgg gctcaatcct catcgtttga cgctgacttt tggtgtatct
      361 gcaagtttct tgaaaaggat gaacttggaa aacaagcgcc ctcgactgtt cagggattta
      421 cctctatttc ctaaggagca attacgtgaa aaatatactg gtggagatat tgtgattcat
      481 gcttgtgcag atgatgagca aattgccttt cacgctattc gcaatctcat ccgtaagggg
      541 agaaatgcgg tgccccttcg ttggagtcag tctggatttg cagctatcgg ggatcgaatg
      601 gagactccgt ggaacctctt tggttttaag gatggaacag caaatccaac caaggagcaa
      661 gactttgacc gcgttatctg ggctgatagt aaggactgga tggaaaatgg ttcttatatg
      721 gcagttcgtc ggattcagat gtttttagag acctgggacc gcactagtct cgaagaacga
      781 gaaaatacct ttggtcgtta caaggaaagc ggtgccccct ttggtaagaa aaatgagttt
      841 gatgaagtgg atttgagtct cttacctgat gattcgcatg tttgtttggc caaagaagtg
      901 gataagccac ttttacgtcg ttcttattct tactcagatg gcattgatga aaagactggt
      961 cagtttgata cgggattgct cttcatttct ttccagaagg atcctgataa ctttgttaag
     1021 gttcaaacta acctaggtgc tactgataag atgaatgaat acatcactca cataggtagt
     1081 ggacttttta cttgctttgg tggtgtggag aaaggaggct acattggtca gaaattattg
     1141 gaaggctaaa agctggttac tagttttagc tttgtcattt ttaattcttt ccccagcagg
     1201 tgcccaagaa agcttgagtt ttttctttgt gaaaatcaca gatgcatcca aaacggttaa
     1261 aaatggtggt cagactgaga cccagaaact cgttacgaag atggcatcag acttcgaaag
     1321 agtagaaaat aaggattctg aggttggtaa gattgttaag gaaaagttag ctctatctgg
     1381 agatattact gaagccaaac tcaccgaaat ttcctcagct ctattagctt ttgaaaaaga
     1441 acaaaatcct gttgacctag atgcggaaaa ggaaaaattg gtaaaccgtc taagtcctcg
     1501 ttttgaaacc ttagagcagg ccattgcctc caaagatttg gaaaaagtcc gagaagcttt
     1561 taagaaaatg aattccactt ggaccatcaa tgaaagtgtg gttcgtgaca atagtacagc
     1621 tcattatgga cgtgttgaaa cagctatttc cttcctgcct agtagcatgg aaaccaaacc
     1681 tacagatgag tctggaacat gaaaacagca gttgatttca agaaacaaaa aagaacagcc
     1741 gaaactgttc tcttatcatt atttgagacc gtattttttg ttgaaacgat ccacgcgtcc
     1801 atctgcttga gtgaactttt gacgtccagt gtagaatggg tgtgagtctg atgaaatttc
     1861 cacacggatc aatgggtaag tttcgccttc gaactcaact gtttcgttag agcgttttgt
     1921 tgaaccgcta aggaattggt aaccagtagt tgtgtccatg aagacaactg ggcgatattc
     1981 tggatggata tcttttttca ttttgcaata tttcctttct gccatggtct ctttgcgagc
     2041 catagattgt taccatacta gtctatcaga ttctgaaaag tttggcaagt attttatcag
     2101 tttttaagca agttttttaa cttttggtag atgatttcgt tttcttctag gctataggaa
     2161 ttagcaccac ttgctagagg gtggcctcca ccatcatgct ccttggcaat ttcattgata
     2221 ggatggactt tactgcgtaa gcgaactcgg tagtggccat cagcctgttc gacaaaaatt
     2281 ccccagagac tcactctgtc aatgcgtcca ggtgcaccta caatggccgc agtttcagca
     2341 tcggttatat tgtattgttt caagattttc tgactcagga taacgcgagc agcaccattt
     2401 tcatccactt ccagatggtc gtagatgtag ccttgcagtt tagcaatttt gtagctcata
     2461 gtgtccattt tgcgagtgag agccgcaaag tcaaagttat gttctctcaa ataagcagcc
     2521 aggcgaagag tccgtgcagt ggtagaaggg tagaggaagc gacctgtatc accgacaatt
     2581 cctgcaaaga gcaactcagc atcgcgatct gccaaggcta gttgggttgt ttgggcaaat
     2641 agggtaatca tctcgctagc gctacttgaa ctagtatcga cccaagacag gtcaccgtat
     2701 acatcatcat ttggatggtg gtcaatctta atgagaaaat caccttgact atagcgctta
     2761 tcatcgatac gagcagtatt agctgtatca cagacgatga caagtgcgcc ttggtaggct
     2821 ctatcttcaa caagatccat ctcagccatc caagtaagag ttggttcatc aaaaccgacg
     2881 gctttgatgg ttttttctgg gaaatgatgt tccagcaagg ctttcaatcc cacctgactt
     2941 cccaaggcat cagggtctgg tttcatatga cgatgaatga taatggtgtc gtattcttta
     3001 attttttcta aaatttgttg gcaaatctcc ataaataacc tcaattcttt ctcatttcat
     3061 tgtagcacaa gaatttttat ttttaaaatg aaaaagatgt gatataatgg agaaagataa
     3121 attgaggagg acgatatggc attagcaaaa attgtatttg ccagtatgac cggtaatacc
     3181 gaagaaattg cagatattgt agcagacaaa ttacgtgact tgggcttgga tgttgatgtt
     3241 gatgaatgta caactgttga cgcttcagac ttcttggaag cagacatcgc tatcgttgcg
     3301 acctatactt atggtgatgg tgaattgcca gatgagatga tggacttcta cgaagaccta
     3361 gcagatctca acttgaatgg caaaatctac ggagtggtcg gctcaggaga taccttctac
     3421 gatgaattct gtaaggctgt tgatgacttt gaccgtgtct ttgtgtcaac aggagcagaa
     3481 aaaggttcag agtgtgttaa agttgatctt tctgccgagg aagaagatat tgaacgcttg
     3541 gaacaattcg cagaagaatt ggctgctaaa gtaggataaa cataaaagtg cgctgatgta
     3601 atcaatcagt gcatttttct tatcgagagt tgggatttta ctagcctaat tgatggcttt
     3661 ttgatacaat aattcaaata aaggaggaga ctgtatggat ttagatatta ttcgtcaaga
     3721 aatcgatcaa atcgacgacc aaattgtcaa actgttagaa gaacgaatgc atttagttga
     3781 gggggtggtt gcttataaga aagcttcagg taaaccgatt ttagatacta agagagaaga
     3841 agttattttt gaaaaggtta ggagtcgtgt agaggacaag cgctatcagg agactattgt
     3901 cgcgactttt tcggacatac tcaaacgttc gcgtgattat caggatcaaa atatcaaatg
     3961 aaaaaagaac aattttatcc gctaggaatt tttctagctg ctatgttggg cggacttgtc
     4021 cgatatctag tttccacctg gttaccagcc agtccagact ttccttgggg cactctcttt
     4081 gtcaactatc tgggaatttt ctgcttgatt tttcttgtca agggctatct ggtctataag
     4141 gggactagta agggcttgat tttagcactg gggacgggtt tttgcggagg tttaacaact
     4201 ttttccagcc taatgcttga tactgtgaag ctgcttgata cagggcgtta tcttagttta
     4261 gtcctgtatt tgcttttgag catcggtgga ggcctactct tagcttattt tctagggagg
     4321 aagaaatggt aatcgtctat cttgcaattg cttgtggttt cggagcactc gtacggtatt
     4381 tcttttctcg ctataatcaa gcttctaaat tgccactcgg aacgctcata gctaatcttt
     4441 taggttgttt tttaattgga gtattctaca atcatgtaga gtctaaggaa gtatatgcta
     4501 ttctagcaac aggattttgt ggcggtttaa caactttttc gaccttgaat gacgaacttc
     4561 aaagactgct aagtgataag aaggtctttt attcttacct gactttgact tacataggtg
     4621 gtttggttgc gattttttta ggaattttgc tataaatttc tttacttttt tttagaaatt
     4681 tggtaaacta tatcttgtgt gtaatggacg cacaaaaata cagtttatcc gctgaggaag
     4741 attcctcaag attgacaaag ataggagaat aaaatgaatc cattaatcca aagcttgact
     4801 gaaggtcaac ttcgtacaga tatcccatca ttccgtcctg gtgacactgt tcgtgtacac
     4861 gcgaaagttg tcgaaggtaa ccgtgaacgt atccagattt ttgaaggtgt tgttatcgca
     4921 cgtaaaggtg ctggaatctc agaaaactac acagttcgta aaatctctaa cggtgtaggt
     4981 gttgagcgta tcttcccaat ccacactcca cgtgttgaaa aaatcgaagt tgttcgttac
     5041 ggtaaagtac gtcgtgcgaa attgtactac ttgcgtgctc ttcaaggtaa agcagctcgt
     5101 atcaaagaaa tccgtcgtta attcgactaa aaaactctgc ttttcagcag agtttttatc
     5161 tagctccctt agttcaatgg atataacaac tccctcctaa ggagtagttg caggttcgat
     5221 tcctgcaggg ggcagtaatt agacatcaaa aaccgctcag ctgagcggtt tttatctatt
     5281 ctttcctttt acagtaccaa tgtacgaata gcatgggcaa cgccggattc gtcatttgtt
     5341 ttggtgatgt atttggcgat ttttttgatt tctggatttc cgttttccat gactacaggg
     5401 ttgccaacga cttccagcat ggcacggtca ttttcttcgt ctccgatagc catggtttca
     5461 tctttggtta atcctagttt ttcagctaag tgagtaatag ctgaaccctt gtctacattc
     5521 tttttaagga gttcgaggta gaaaggagca gatttgttga tagagtagtg ctcgtaaaat
     5581 tcggctggta ttttttcaat cgcagcatcg aggatttctg gttcatcgat gaacatacac
     5641 ttgacaattt ccttgccagc catttcttca ggagtgcggt agaagatagg catgctgacg
     5701 agggttgatt cgtgcacagt gtatgttccg atattgcgat tggcggtata gataccgtcc
     5761 ttagtaatag catgcatgtg aacaccaagc ttgcgactga gaaattccat atccagataa
     5821 tcctcatagg tcaaggattc gctgataatc tcatggccag tatcagtctc ttggacaagg
     5881 gcaccattga aggtcaccac atagtcacct tggtctctca actgcaagtc gtccagaagt
     5941 ttggcaacac ctgcgatggg gcggccagtt gcaatcacga ctttgacacc agcttctttg
     6001 gcatcttgga tggcagaaaa gacttcagga gtgatttcct tttggctgtt gactagggtt
     6061 ccgtcaatat cgacggcaat tagtttaata ctcataaaat tcctcttcta gtttttattt
     6121 ggggtaaaat gatcgttctc aatcaagtgt aaaaattgct gggtaatgct tgcaaagatg
     6181 ctgttttggt ccaacatttc ttttggaaaa taaaagcgat tatctccgtg gcgactgcca
     6241 gcaagggatt ggacgatagg agacaggcta gagagttcgg ccagttctcc atttttttgt
     6301 aaaatctcaa tctgtgtccg tgggttttca gattcgggac gatagatatc ataagggagg
     6361 tcaaagttct tatgaatggc agtgtagtag tcgggatcaa agccgatatc ctcaaccaat
     6421 tttctcatgc tagtaagttg atcttggtcc tcttgtgaaa aggtaatgga tttaaagacc
     6481 ttgcggttga caaagcgatg cgataaatct gcaagaatct tgtcaggact ggtcatccaa
     6541 agctggaagt aggtattcat cacgccatca tccagagcca gatagtcagt caaggtcaca
     6601 tttttttcga agaaaggcag gaggtgtgga gaagttcggg caaagaaatc cttgtcctca
     6661 ggatagagtt ccttggcgcg tttgagaaga ttctgtagga gaacttccat ggcgcgtgtt
     6721 gcggggtgga aataaacctg catgtacatc tggtagcgac tgaggacgta gtcttcgatg
     6781 gcgtgcatgc cattgcgctg aaaggcgata ccattttcga taggacgaat gactcggagg
     6841 attcgagtca ggtcaaattc cccataggat gctcctgtaa aataggagtc acgcaagaga
     6901 tagtccatgc ggtccgcatc aatctggcta gaaatgagct gcacgacctg cttattagga
     6961 taggtatggt caatgacact ggccaccttt tctgggaaat caggtgccac ttgtagcagg
     7021 acttggtgaa tctctgtctc aggattttga ataatctcct gagtaatggc ttcatggtct
     7081 gtatcaaaga gattttcaaa agtatgggag taggcaccat gcccaaggtc gtgtaggaga
     7141 gcagcggtca tggtcaagag agactcggca ggattccatt cctcaggata tttttcttcg
     7201 aaaatctctg tgatgcgtcg tgcaatttca tagactccta gacagtgaga gaagcgacta
     7261 tgctctccac cgtggaaggt ataactggaa gttcccagtt gtttgatccg gcgcaaacgt
     7321 tgaaattctt ttgtattaat caagtcatag atgatttgat tattgacatg gatgtagttg
     7381 tgaacagggt cacggaatac tttttcgttc atatgaccat tatagcaaaa tcctgctctt
     7441 tttggtaaaa tagtaggaca agagacaaga aagagggcct gatgtgaaga ttcggatgcg
     7501 aaatacaatt cagtttgatg agcagttgga agtgattgac cagctttatg atgtggaagt
     7561 gcatgaaaaa ggagattata gctacctgct tttctataat gaggaaaagg aaaaagtagt
     7621 gattaaattt catggtcaag aacttgtgat gagtcgattt tccaatccca agaccattat
     7681 gcgctttcta aaggatagtg atagtttagc ctatattccc acacctatgg gtatgcagga
     7741 gtttattatc caaacgaatc gttatcaagt ggatgggcaa aagattgaac tagattatca
     7801 actacaaaat caagagggac atccctttgc cagctatcaa ttggaaatta cttggggcta
     7861 ggctcatgtc tttttcaaat ttagctatct atcttcttgg atcggcttcc tagtgtggta
     7921 gattaggcta atttttggta taataaaagt tatggaaatc gaaaaaacca atcgtatgaa
     7981 tgcgctcttt gaattttatg cggcgctttt gacagataag caaatgaatt atatcgagct
     8041 ctactacgct gatgattaca gccttgctga aattgccgag gagttcggtg tcagtcgtca
     8101 ggctgtctat gacaatatca agcgaacaga aaagattctg gaagattatg agatgaaatt
     8161 gcacatgtac tcggactata ttgtccgcag tcagattttt gatcagattt tggagcgcta
     8221 tcccaaggat gactttctgc aggagcagat agaaatttta acaagcattg ataatagaga
     8281 ataagaggaa gaaaaatggc atttgaaagt ttaacagaac gtttgcagaa cgtctttaaa
     8341 aatctacgta aaaaaggaaa aatctctgaa tctgatgtcc aagaggcaac caaagaaatt
     8401 cgcttggcct tgctcgaggc cgacgttgcc ttgcctgttg taaaggactt tatcaagaaa
     8461 gttcgtgagc gtgcagtcgg gcatgaggtc attgatacgc ttaatcctgc gcaacagatt
     8521 attaaaatcg ttgatgagga actgacagcc gttttaggtt ctgatacggc agaaattatc
     8581 aagtcaccta agattccaac catcatcatg atggttggtt tacaaggggc tggtaaaaca
     8641 acctttgctg gtaaattggc caacaaactc aagaaagaag aaaatgctcg tcctttgatg
     8701 attgcggcgg atatttatcg tccagctgcc attgaccagc ttaagacctt gggacaacag
     8761 attgatgtgc ctgtctttgc acttggaaca gaagtaccag ctgttgagat tgtacgtcaa
     8821 ggtttggagc aagcccaaac taatcataac gactatgtct tgattgatac tgcgggtcgt
     8881 ttgcagattg atgagctcct catgaatgag cttcgtgatg tgaaagtatt ggctcaacca
     8941 aatgaaatct tgcttgtcgt tgatgctatg attggtcagg aagcagccaa tgttgcgcgt
     9001 gagtttaatg ctcagttgga agtgactggg gtcatcctta ccaagattga tggtgatact
     9061 cgtggtggtg ctgctctgtc tgttcgtcac atcactggaa aaccaatcaa gttcactggt
     9121 acaggtgaaa aaattacaga tatcgaaacc ttccacccag accgtatgtc tagccgtatc
     9181 cttggcatgg gggatatgct cactttgatt gagaaagctt ctcaggaata cgatgaacaa
     9241 aaagcccttg aaatggctga gaagatgcgc gaaaacacct ttgattttaa tgatttcatc
     9301 gatcaattag atcaggtgca aaatatgggg ccgatggaag acttgctcaa gatgattcca
     9361 ggtatggcca acaatccagc ccttcaaaac atgaaggtgg atgaacgcca gattgctcgt
     9421 aaacgtgcca ttgtgtcttc gatgacacct gaagagcgtg aaaacccaga tttgttaaat
     9481 ccaagccgtc gccgtcgtat tgctgctggt tctggaaata cattcgtcga agtcaataaa
     9541 ttcatcaagg actttaacca ggctaaacag ctcatgcagg gtgttatgtc tggggatatg
     9601 aataaaatga tgaagcaaat ggggattaat ccaaataacc ttcctaaaaa tatgccaaat
     9661 atgggaggaa tggatatgtc tgcccttgaa ggaatgatgg gacaaggcgg tatgcctgac
     9721 ttatcagctc tcggaggagc aggaatgcca gatatgagcc agatgtttgg tggcggtttg
     9781 aaaggtaaaa ttggtgaatt tgccatgaaa cagtccatga aacgtatggc taacaaaatg
     9841 aagaaagcga agaagaaacg caagtaagac aagagattga tgcaaatctc atttgatgag
     9901 aaaataaagt aaaaatttct atgataaaac gtacagtatc aaggttttag aatatctgat
     9961 attatacgtt ttttgatttt aataattttg ttaagacact tttattatgg tatacgaaaa
    10021 atccactcag ctgtctgagt ggattaggtg tatttagact cttagtcttt attttcgtat
    10081 ggcaagatca agttcaagat gattcctgtc atggctgaaa gggcagtacc tgaaagtgta
    10141 actggaccaa gtttaaggat agctcctcca agtccaagaa ccaacatagc acttgcgatg
    10201 atgaggtttc gcatttgagc gaaatcaaca cgttctttaa tcaagacttt caaaccattg
    10261 ctggcgataa ccccatagag aaggattgac ataccaccaa gtacagcgtt tggaatagtt
    10321 gaaatcaagg cagtgaattt accaaggaag ctgagggcaa tcgcgatgaa ggcagcgtta
    10381 cggataactg agacagaagc gatacgagtc ataccgataa cccctgtatt ttctccgtaa
    10441 gttgtattgg ctggtccacc aaggaaggca gaaacagaag ttgcgatacc gtcaccaaga
    10501 agagtacggt gaagacctgg ttcttttaag aattgacgac cacagatttg acccaaaaca
    10561 gtatggtctc cgatatgttc agaaattgtt acgatagcga ttggcaagat agcgatggct
    10621 tctggaccaa agtaaagatt gtactcttta aaggcaccac ctgtgctaaa tggcaagtag
    10681 aaaccaggaa tttcaaacca gttagcttct aggacaggcg taaagtcaac caaaccaaga
    10741 gttagtgcga agaggtaacc accgataatg gcaaagagga atggaatgat tcgtaggaag
    10801 ccttttcctt ttgtattgat aaaggcagca attaggaaag taacaacggc taccagagca
    10861 tttttccaat ttccgtctgc tacaagacct gcattggtaa cagctgaacc tgcaagtcca
    10921 agaccgataa cgatgatcat aggaccgata atgattggtg gcaagagttt atcaatccat
    10981 tttgttccta caaatcggat gctggtagca acaaggacat agaccaaacc agtcaagata
    11041 acccctgttt gagcagcaga tacatccccc cccatttctt tcatagccag tgacatagct
    11101 gtgataaagg cgaatgaaga acctagataa actggaactt taaaaccagt agcaagcatg
    11161 tagatgagtg ttccaacacc tgaagcaaaa agggcaacag atacaggcat tcccaaaatc
    11221 aatggtacca agatggtcgc accaaacatg gcgaaaacgt gttggaaact aaggagaatt
    11281 ccttttccag ccgaaggacg ttggtcaacg tctagtaaca aatcaacagt tgattcttgt
    11341 ttcatataaa cctcactttt gggcatcaaa aaagagccca ttattttaca gcaataggcc
    11401 ctcagagtaa gacttcttta aaatttagat tttaaagagt tttaaatatt tctgcgtctt
    11461 cgtcacctca cgggatgaca ttaaaaacct ttgcttagga tagtatagca gaaaaaaatg
    11521 attttgtaaa tcattttttc ccgagcctag aaataaaaga gcgaggctga ttttgtaaac
    11581 atttgtttac taaaaaattt aaagtgggcg tttatttggc ataccagcct tacgtggata
    11641 tttatttggt gtttcttttt tcttttctac cactgtgata tagcgcggat ctctattcgg
    11701 tagggcgtag ctgagattgt cttcgacctt actaaaaagg agattgaggg cattcttagc
    11761 ttctaataat tcctcaggcg cattgctggc cttgagtgcc aatagttttc caccaacctt
    11821 aaggtaggga atggtcaatt cagataggac ctgcatacgg gcaaccgcac gagctgttac
    11881 aaaatcatat tgagcacgga agttcttgtc ttgggcaaaa tcttcggcac gtccgtggta
    11941 gaaatgaact ccgttcaaat ccagttcttg agccaagagt tgtaggaagt tgatgcgctt
    12001 attgagtgaa tcaataatgg tcacatctaa ctccggatag agaattttca ttggtagact
    12061 aggaaatcct gccccagccc cgatatcaag aagtttgata gtttcattgg gaatcaaacc
    12121 ttgaagaatg ggtgcaatcg aatcgtaaaa atgtttgaga taaacttctt ccttgtccgt
    12181 aatcgccgtc aaattaatct tctcattcca ctcgaccaag agctcaaaat aacgttcaaa
    12241 ttgttctttt tgctggtccg aaagtggaag attctgctcg gcaagcaagt tgtaaaatgt
    12301 ttttggtttc atagttattt ccttctttag tatcatctta ttttaccaca atcatagaaa
    12361 atttgatata ctggtactaa tctaaaagca gaaaggactt atattatgac ttggattatt
    12421 cttggagtta tcgctcttat tgttattttt gtgattgtta gctataacgg tttggttaaa
    12481 aatcgtatgc aaaccaagga ggcttggagt cagattgatg ttcagttgaa acgtcgaaat
    12541 gacctcttgc cgaacttgat tgagactgta aaaggttatg ccaaatatga aggttctacc
    12601 cttgaaaagg tggcagaact acgtaaccaa gtggcggcag cgacttcacc agcagaagct
    12661 atgaaagcca gtgatgccct cactcgtcag gtttcaggta tttttgcagt tgcagaaagc
    12721 tatccagatt tgaaagctag tgctaacttt gttaaattgc aagaggagtt gacaaacaca
    12781 gaaaataaaa tttcttactc tcgtcaactc tataacagtg ttgtcagcaa ctacaatgta
    12841 aaattagaaa ctttcccgag caatattatc gctggaatgt ttggatttaa agcggcagat
    12901 ttccttcaaa cacctgaaga ggaaaagtcg gttcctaaag ttgattttag cggtttaggt
    12961 gactaagatg ttgtttgatc aaattgcaag caataaacga aaaacctgga ttttgttgct
    13021 ggtatttttc ctactcttag ctcttgttgg ttatgcggtt ggttatctct ttataagatc
    13081 tggacttggt ggtttggtta tcgcactgat tatcggcttt atctacgctt tgtctatgat
    13141 ttttcaatcg acagagattg tcatgtccat gaatggagcg cgtgaggtgg atgagcaaac
    13201 ggcaccagac ctctaccatg tagtggaaga tatggctctg gtcgctcaga ttcctatgcc
    13261 ccgtgttttc atcattgatg atccagcctt aaatgccttt gcgacaggtt ctaatcctca
    13321 aaatgcggct gttgctgcga cttcaggtct actagctatc atgaatcgtg aagaactaga
    13381 agctgttatg ggacatgaag tcagtcatat tcgtaattat gatatccgta tttcgactat
    13441 tgcagttgcc cttgctagtg ctatcaccat gctttctggt atggcaggtc gtatgatgtg
    13501 gtggggtgga gcaggtcgca gacgaagtga tgatgaccga gatggaaatg gtcttgaaat
    13561 cattatgcta gtggtttccc tactagctat tgtactggca cctctcgctg caaccttggt
    13621 tcagctcgct atttctcgtc agagggaatt tctggcagat gcatctagtg ttgagctgac
    13681 tcgcaatccc cagggaatga ttaatgccct agataagttg gacaatagca aaccgatgag
    13741 tcgccacgtc gatgatgcta gcagtgctct ttatatcaat gatcccaaga aaggtggggg
    13801 gttccaaaaa ctcttttata cccacccacc tatctcagaa cggattgaac gtttaaaaca
    13861 gatgtaaaag aatccagagg tcgtctctgg atttttgcta tgttgcaaat ttataaatct
    13921 tctaaattaa ctagcttcaa accgtgttct gtcatgcgat agatgatcga gcagacttct
    13981 tttaagaaac gacggtcatg cgaaacagtg atgagaccgc ctggataggt tgcaaagagt
    14041 tttctgattt ggggttgaga agtgggagaa aagtttcgtg tgggttcatc cagcaggaga
    14101 aagtttggtt tgcgcaggac tagatccaaa agcaggagtt ttccctgttg tccgccagat
    14161 aaggagcgaa tttgatgctg catttctgga taactgaaat tgagactggc taggtgagag
    14221 tggattttct gaagttcctc tttttcccca gttttgctga tataagctat tggtgataaa
    14281 tccaattgta gttttttgtg gtaatcttgt ggcataaaac caagggaaat ctctctttta
    14341 tcattcagaa gttgctttaa tttggctaac agagttgatt tcccaacacc atttggcccg
    14401 ataataccga ttttttcttg cccacggaca gttagttgta gtttttgaac caaaactcgg
    14461 tcgtcaatgg acaaattttc tttttccagt tggactaaga ctttagaagc tggtaatggt
    14521 tggatgtctg aaaagaaaag ttggatttgt tcctcttcaa gtggtttttg agtcatggac
    14581 tgagctgcct tttcgtagcg tttttcttgt gagaggacag ttttcatctt tttagacaat
    14641 aggcgaccgg cagtactatc tttggtagct cgaagcgcag tttctacatt ttgcttaact
    14701 ctccgatgtt tttccatggt tttatcgtag gctctttggt tgttagcagc ttgctgactt
    14761 tgtttggcaa aattagcctt tctctgctca ctatagctat catagtctaa atgctctact
    14821 agcgtttccg cttctttacg gtgtttgacc agtcgcaagt gaacaatagt gtctgccgtt
    14881 tcagaaagaa agtcttcatc atgggaaatg aaaataacgg tttgcctggt cttttgaatc
    14941 tggcctttta gccaatcaac tgtctcaagg tctaggtcat ttgaaggttc atctaaaaat
    15001 agaatctcaa agggtttggc taactcatgg ataagctgaa ttttcaaagc ttctccccct
    15061 gatagattgc caatctcttg gtcacttgcg aaacgattgc tatcaaaatg caattcctcc
    15121 gccaaacgat agaggatact gtagtctaaa tcaatagaat ctaaaaagaa gtagtcgtgt
    15181 aaagttttct ttttcagctc ctcgggaagt ttttgaggaa tgtaggccag tgactgatag
    15241 tcagattgga tgtttccctt gatagtgaaa tcagacaaag cttcccccat taaaatttta
    15301 agtaaggttg atttgccatt tccttcttca ccaataatag caaccttttc cccgtcttgg
    15361 atggtcatgg ttaggtcaga tacaagatct cgtaaatctt tgttttgtgt gatggttaga
    15421 tgattgattt ttatcatatg atttcccttt ctagaatgtt catagtgcat aacaaaaagc
    15481 tctactttac ctagtagagc ccaaagtcta tgtcaaaaaa actctattaa catgccagaa
    15541 aaagagcata aaagagcaca caaaaagaga caaaaacaag atctactaaa taaaggttct
    15601 ttatttgata gacttagttg ttcatgtctc ccttacctcc gagtattagt atctttatat
    15661 tataccttta aggaaatttt gtcaacagaa aactggaaat tctatgctct aaaattcaaa
    15721 aacaggtcca tagagactta gtacgtgttt gacatgctcg taatggaatt tatcatagtt
    15781 tcgccaagca gtgcgtgctt gatcgtttag ttttaggcta cccagtccaa tcagaagact
    15841 ggtaggttgg taaaatttct caagatcaat taagatactg ttgttcaact gttccgtttt
    15901 tttgagctct tgcatagtag tgtttagcag ctcttgtagt cgaatatcat ctgccgtacc
    15961 ctgtttacag ttttggtagc ttttatttaa cttggatagg agttgaatga gtttcttgtc
    16021 ttccatgtga gcatcctcct tgatctgatg tactctttcc ctatagtata gcactaaaaa
    16081 ataaaactat aatagtaaat atgttaaaat tttgaatttt aattacaaag tttggtgtgc
    16141 tgatttgtag ccttttcatg gtataatcaa gagagtaaat ctttatggag gaagtatgaa
    16201 attaaatatt caagaaattc gtaagcagtc tgaaggtttg aactttgaac aaacgttaga
    16261 tttagttgat gacctgcgtg cacgtaatca agaaatttta gatgtaaaag atatccttgc
    16321 agttgggaaa gtacaatatg aagaccgtat gtatttctta gattatcaac tatcttatac
    16381 cattgttctt gcttcgagtc gcagtatgga gccagttgag ttagttgaat cttatccagt
    16441 cacggaagtt ttcatggaag gcgcaactaa ccagctagat caagaagttt tagatgatga
    16501 cttggtcttg cccatcgaaa atggggagct tgaccttgct gagagtgtat cagacaatat
    16561 cctgctaaac attcctatca aggtcttgac ggctgaagaa gaagctggtc aaggatttat
    16621 ctcaggaaat gactggcaaa tcatgacaga ggaagaatac caagctcaaa aagcagtaaa
    16681 gaaagaagaa aacagtcctt ttgctggctt acaaggacta tttgacggag atgaataatg
    16741 gtcttgtcaa aaaaacgagc acgaaaggtg ctagaagaaa tcattaccct cttcccagat
    16801 gccaagccta gtcttgattt taccaatcat tttgaactcc tggttgcggt catgttatca
    16861 gcccagacga cagatgcagc ggtaaataag gccacaccag gtctctttgt tgcctttcca
    16921 acaccccaag ctatgtctgt agcgacagag agtgagattg cttcacatat ttctcgcttg
    16981 ggattgtatc ggaataaagc taaattcctt aaaaaatgtg cccaacagtt actagacgat
    17041 tttgatggtc aagtccctca gacacgtgaa gaattggaga gtttggcagg tgttggtcgc
    17101 aagacagcca atgttgtcat gagtgtagga tttgggattc cagcctttgc agtggatact
    17161 catgtggagc gtatttgcaa acaccacgat attgtcaaaa aatcagcgac gccacttgag
    17221 gtggaaaagc gggtcatgga tatcttgccg cctgagcagt ggttagctgc ccatcaggcc
    17281 atgatttatt ttggaagagc catttgccat ccaaaaaatc cagagtgtga ccagtaccca
    17341 caattatatg attttagcaa tttgtaagat gctacattga aactttttgc ttgattttaa
    17401 gcatgctttg tgctatagta aatgataact aaatattcct ttaaacctgt cccgtgaggc
    17461 aggcaaggag cgcgataaag tagaagggtg aagtctatac tgtgtgcagt agggctcgct
    17521 tggctataaa tttcaagtct ccttgtttaa ggagactttt ctttttggag gtttgtcatg
    17581 aaaacaaaag aagttgtaga cgaattgacc gtcaaacgag cgattacgcg tattacttat
    17641 gagattatcg aacgcaacaa agatttgaat aagatcgtct tggctggtat taaaactcgt
    17701 ggtgtcttta ttgcccaccg aatccaagaa cgtttgaagc agttagaaaa tctttcagtt
    17761 cctgttgtgg aattggatac taaacctttc cgtgatgatg ttaaaagtgg agaagatact
    17821 tctttggttt ctgtcgatgt gacagaccgc gaagttatct tggtggatga tgtgctctat
    17881 acaggtcgta ccatccgtgc tgctattgat aatattgtcg gtcatggtcg tcctgcgcgt
    17941 gtgagtttag cagttctagt cgatcgtgga catagagaat tgccaatccg tccagattac
    18001 gttggaaaaa atatcccaac cagtcgttct gaagaaatca tcgtagagat gacagaactt
    18061 gatgaccaag acagagttct gattactgaa gaagcttaga aagttaaagg agtagccatg
    18121 tcagaaaatc aacaagcatt gaaccatgtg gtgtccatgg aagacctcac tgtcgatcaa
    18181 gtaatgaaat tgatcaagcg aggaattgag tttaaaaatg gagcccagct tccctatgaa
    18241 gaccatccga ttgtttccaa tctcttcttt gaggattcta cacggacaca taagtccttt
    18301 gaagtcgcag agattaaact tggattggaa cgacttgact ttgatgtgaa gactagttcg
    18361 gttaataagg gtgagacact ttatgacacc attttgactc tgtctgcttt aggagtggat
    18421 gtctgtgtga ttcgccatcc agaggtcgac tactatagag aattgattgc tagtccaacg
    18481 attacgactt ccatcatcaa tggtggagat ggttcgggcc aacaccctag ccagagcttg
    18541 cttgatttga tgaccattta tgaggaattt ggccactttg agggtcttaa agttgctatt
    18601 gcaggtgact tggatcactc acgcgttgcc aaatccaata tgcagatttt gaaacgcttg
    18661 ggagctgaac tctttttcgc tggacctgag gaatggagaa gtcaagagtt tgcagactat
    18721 ggacagtttg taaccattga tgaaatcatt gatcaggttg atgtcatgat gtttctccgt
    18781 gtgcaacacg aacgccatga tagtggagct gtattttcaa aagaagacta ccatgcccaa
    18841 catggcttga ctcaagaacg ttacgatcgt ttgaaagaaa cagcaatcct catgcaccca
    18901 gctccaatca atcgtgatgt agaaatagca gaccacttgg ttgaagcacc aaaatcacgg
    18961 attgtccaac aaatgaccaa tggtgtcttt gttcgaatgg caatcttaga atccgtacta
    19021 gcgagtagaa acgccaacta aaacacaaga cgttaaaaga cgccagtgag cgtccacgag
    19081 aggtgaaaat atgacaaaaa gaattctagt attagaagat ggcacagttt ttgaaggcaa
    19141 ggccttcgga gcagatattg atgtaacagg cgaaatcgtc tttaatacag ggatgaccgg
    19201 ctaccaagaa tccattacag accagtctta taatggacaa atcttgacct ttacttatcc
    19261 tttggtagga aattatggta ttaatcgtga tgattatgaa tccattattc caacttgtaa
    19321 gggagtcgtt gtttttgaag aagcgcgtag agctagcaac tggcgcaacc aaatgacctt
    19381 ggatgaattt ttgaaagcca aaaaaattcc agggatttca ggaattgata cgcgtgctct
    19441 taccaagatt atccgtaagc atggtactat gcgtgcaacc ttgacccatg ttggggacag
    19501 tatggaccat gtgacggacc agctccaagc aacagtttta ccgacagaca atatcaaaca
    19561 ggtttctact aaaacgtctt atccagctcc aggagttggt ttgagcgtgg tgctagtgga
    19621 ctttggtctc aagcactcaa tcctacgtga actttctaaa cgcaactgta acgtgacagt
    19681 tgttccttat tcgacaacgg ctgaagaaat tctccatctc aatcctgatg gggttatgtt
    19741 gtcaaatggt ccaggtaacc cagaagacgt tccacaagca ctcgacatga ttcgcggtgt
    19801 acaaggaaaa attccaatct ttggtatttg tatgggacac caactctttg caatggcaaa
    19861 cggggctaag acctataaga tgaagtttgg ccaccgtgga ttcaaccatg cggtacgtga
    19921 aatcgcaaca ggacgagtag acttcaccag ccagaaccat ggttatgcag tcagccgcga
    19981 ggatttgcca gagcacttga ttattaccca cgaagaaatc aatgacaagt cagtggaagg
    20041 tgtgcgccac agataccaac ctgctttctc tgttcaatac cacccagatg cagctcctgg
    20101 gccacacgac gctagctacc tatttgacga gtttatcgag atgatggaag tttttaaaca
    20161 atcaaactaa gaacgagtaa aagctcgtcg gagaatttat gtaactgaac acggacggaa
    20221 agctcagaat gtagagaaat caacttggat tgtcaatcct tccttgattt tctaaaattc
    20281 aatcgctttc tattcgtcct ttgtatctta tttaatgtcg ccctgagagg cgacgaatag
    20341 aaaggagaag ggtgctccgt atttgctgaa ctgaatacgg gctacggacg gtgctaaaaa
    20401 gatagttatt cctagaactg acagttcttc gtcataactc ctattttagc tttgtccgct
    20461 tgacgccctt aatatcttat atatgcctaa acgtactgat attcaaaaaa ttatggtgat
    20521 tggttctggt ccgattatta ttggccaggc tgctgagttt gactacgctg ggactcaggc
    20581 ttgcttgtcg ttgaaagagg aaggttatga ggttgttttg gttaactcaa atcctgcaac
    20641 catcatgacg gacaaggaaa ttgctgacaa ggtttacatt gaaccgatta cacttgagtt
    20701 tgtgacacgt attcttcgta aggaacgtcc agatgccttg ctaccaacac tcggtggtca
    20761 gacaggtctc aacatggcca tggaattatc taaaaatggt atcctagacg agcttggcgt
    20821 tgaacttctg ggtaccaaat tatctgccat tgaccaagcg gaggaccgtg acctctttaa
    20881 acaattgatg gaagagcttg aacaacccat tccagaatct gaaattgtta acacagtaga
    20941 agaagcagtt gcctttgcag cgacaattgg ctacccagtc atcgttcgtc cagcctttac
    21001 ccttggtggt actggtggtg gtatgtgtgc caacgagaaa gaattgcgtg aaatcactga
    21061 aaatggtttg aaattgtcac ctgttaccca atgtttgatt gagcgttcga ttgccggttt
    21121 caaggaaatt gaatacgaag tgatgcgtga ctcagctgac aatgccttgg ttgtttgtaa
    21181 catggaaaac tttgacccag ttgggattca cacaggggat tccattgtat ttgcccctgc
    21241 gcaaaccatg tcagactatg aaaaccaaat gcttcgtgat gcgagcttga gcattattcg
    21301 tgccctcaag attgaaggtg gatgtaatgt tcagctagct cttgatccta acagcttcaa
    21361 gtattatgtt atcgaagtaa accctcgtgt atcacgttcg tcagcccttg cttctaaagc
    21421 gacaggatat ccgattgcta agttggctgc caagattgca gtaggtttga ccttggatga
    21481 ggttataaac ccagttacag gttcaaccta tgccatgttt gaaccagccc ttgactacgt
    21541 agttgctaag attccacgtt tcccatttga caagtttgaa aagggtgaac gccgtctcgg
    21601 tacacaaatg aaggcgactg gagaagtcat ggcaatcggt cgtaacatcg aggaatctct
    21661 tctcaaggcc tgccgctccc ttgaaattgg ggtgcaccac aatgaaatac ctgaacttgc
    21721 agcagtttct gatgatgcct tgattgaaaa ggttgtcaaa gcccaagatg accgtctctt
    21781 ctacgtatca gaagcaattc gtcgtggcta cacacctgaa gaaattgcag agcttacaaa
    21841 aattgatatc ttctatcttg ataaactctt gcatatcttt gaaattgagc aagaattggg
    21901 tgctcatcca caagatctag aagttttgaa aacagccaaa cttaatggtt tttcagaccg
    21961 taagattgct gaactctggg gaacgactga tgataaagtt cgccaacttc gcttggaaaa
    22021 caagattgtt ccagtttata agatggtaga cacttgtgcg gcagagttcg actccgaaac
    22081 gccatatttc tattcaacct atggttggga aaatgaatct atcagatctg ataaagaatc
    22141 tgtacttgtc ctaggttcag gtccaatccg tatcggtcaa ggggttgagt ttgactacgc
    22201 aaccgttcac tctgttaagg ctatccaggc agctggttat gaagctatca tcatgaactc
    22261 aaacccagag accgtttcaa cagacttctc tgtatcagat aagctttact ttgagccatt
    22321 gacattcgaa gatgttatga acgtcattga cttggaacaa ccaaagggag ttatcgttca
    22381 gttcggtggt caaacagcca tcaaccttgc ggagccattg gcaaaagcag gtgtgaccat
    22441 ccttggtaca caggttgctg acctagaccg tgccgaagac cgtgacctct tcgagcaagc
    22501 tctcaaagaa ttggatattc cacagccacc aggacaaacg gctaccaatg aagaagaagc
    22561 agctcttgca gctcgtaaga ttggcttccc agttcttgtc cgcccatctt atgtacttgg
    22621 tggacgtgcc atggaaatcg ttgaaaacga agaagacctt cgttcttaca tgcgaactgc
    22681 tgttaaggct agtccagatc acccagttct tgtcgactct tatatcgttg ggcaagagtg
    22741 cgaagttgat gccatttcag atggtaaaga tgtactcatt cctggtatca tggagcatat
    22801 cgaacgtgct ggtgtccact caggtgactc aatggctgtt tacccaccac aaaccttgtc
    22861 gcaaaaggtt caggagacca tcgcagacta caccaaacgc ttagcaatcg gtcttcactg
    22921 ccttggaatg atgaacatcc agtttgttat caaggatgaa aaagtctacg ttattgaggt
    22981 caatccacgt gccagccgta ctgttccatt cctatctaag gtaaccaata ttcctatggc
    23041 tcaagtagcg accaagctca ttcttggtca aagtttatca gaacttggct accaaaatgg
    23101 actttaccct gaaagcaccc gtgttcatat caaggcacct gtcttctcct ttaccaaact
    23161 agctaaggta gacagcttgc tcggtcctga aatgaagtca acaggtgaag ttatgggttc
    23221 tgatgctact ttggaaaaag ctctctataa agcctttgaa gcttcttatc tacacttgcc
    23281 aacttttggt aatgtcgtct ttaccatcgc tgatgatgcc aaagaagaag ccttgaactt
    23341 ggctcgtcgt ttccaaaaca ttggttatgg aatccttgcg acagaaggga cagcagcctt
    23401 ctttgctagc catggcttgc aagcccaacc tgttggtaag attggtgatg acgataagga
    23461 tatcccaagt tttgtacgca aaggaagaat tcaagctatc attaacacag taggaacaaa
    23521 acgaactgct gacgaagatg gtgagcaaat tcgtcgttca gccattgaac acggggtgcc
    23581 cctcttcaca gcgctagata cagctaatgc catgcttaag gtacttgaaa gtcgtagctt
    23641 tgttacagaa gcgatttaaa tagaaaaata agatatagca gactgaattt agaacagtac
    23701 acagggatac taaaatattt ctagaaatta atttgaattt tctaattgat tcgttcgcat
    23761 cttatttcaa tctactatag aaaaaagtct ttaaaattat aaaacgcatc atatcaaggt
    23821 ttttcaaaaa ccttgatatg atgcgtttta ttgtgggaat atgtatttca ttttctacta
    23881 aaattatgtt tttgaataac ctctatctta gtagtttgta taatacccct caatcagttt
    23941 ttgcgataag ctttaatgct atgactatac cactcttgca tttcttttga tggtggtgtc
    24001 atataatcgc catacatctg ggttaaaaat tggtcatatt ttttgggaac aggcaacata
    24061 cggccctcaa actcagttaa aatcagttct ttaaaggtat caactgggaa gatttctttc
    24121 atcccttcct taccgatccc aactcctcct tcatattgag gagtgttggt tacagcattt
    24181 ttgactagtt gatcaatttt cttgtaaaag tagcgaggat tgacaaatcg gagagcgtac
    24241 cagctacata atctaagaaa atcttttagt ttgctatcac cgtgaactgc tcgtgatttt
    24301 ttgatataag ctagttgacg aagagccaca tacttatagc tcttgtcgac aatgctcaag
    24361 tctgtaaatc gatcaattgg gaagacatcg atgaaaaggc tggtatcatg acgcttgtac
    24421 ttaacatggt cttctataac agtagaagtg tccaaaatcg atgcgaaatt atggaagtac
    24481 caagaagatg tatcgtagga aagaaccttg tagcgagggt gattttcttc ttcaataatc
    24541 ttcagtaaac gctcataatc ctcacgataa agggaaatat caatatcatc atcccaagga
    24601 atcatacctt tgtggcggat ggctccaagc atggttccat aactgagaaa ataaggaata
    24661 tcatgtttct tacaagtctc atcaatatag tccagcaggg ctagttgaat ttctttaatt
    24721 tctttttttt ctaaatattg catcctaatc ctccaattta taagcgtgaa attcatgact
    24781 gtagaagcgt ttttcttctg gtggtagggt catataatct ccataaaatt gtgtcaaaat
    24841 agtatcaaat ttttcaggtg caggaaggct taaattctca aagggtaaat cgattgtttt
    24901 atcaaaggta ccacttggga agacttcctt ttccttaaat tttgaaggaa taaaagccat
    24961 atactgccca ttttcacgac tatatttttg aatttctttc tcgattttat ttgcaaaata
    25021 acgaggagaa accggtcgaa ggagcaacca aaaggctgtt cgtatccaat cttttaaaag
    25081 gctatcctta tagacaatat ttttatgttt actgaaagac agcagtttga agctttccag
    25141 tttataacaa gtatcaatga ccttaggatc atcaaagcga tctataggga aaatatcgat
    25201 aaagatacca gactcatagg tttttgtatt tcgagtatca ataattttag ttgtactgtc
    25261 ggttatcttg ataaagttgt taaagtagtt cttatcagtt tctaaggata ggagcttata
    25321 cttgcttttt tccttttgaa aaatgttaat aaatcgttgg tagtcttctc taggcatgga
    25381 taaatcaata tcgtcgtccc aagggataaa gccctcatgt cgaaccgccc caatcagagt
    25441 accgtagtta ataatatagt tgatattgtg ctttttacag agagtatcaa tataattcaa
    25501 aatttctaat tcaatttgtt tggcatcttc aacggttagt tgtttcattt taaactccta
    25561 agatttttta aatttatttt ttaaggctag gacatggttt aaaaattcat agaaaatgct
    25621 atcttttgtg aagacaagta gactaatata agagatagct gatagcaaga caatcaaacc
    25681 agtattaatc aaaaatggca aattaatgac catatccaca ggatacatga aattaatcag
    25741 gaaataaatt gctacaaagg aaagtgaaaa gagagagtat cgaacagtat agctaaagat
    25801 atgtcccaag tggatgagtt gttttctatg gatgaaaatg atatagaaaa caagtagaga
    25861 agtctctgat aacatagttg tcagtaagta gtattcagga gccacgatat ggttgaaaaa
    25921 gaggagacta ttcaagccca aattgagtag cccagcaaag actgtataga ctgtgatacg
    25981 tttttcatag ccattggtaa agagaatttg ggaaccaaga atggtatcta aggccaggat
    26041 aatcgtacga aaagcgaaga gagaggtcaa gatgccgcct ccgatatatt tttcactacc
    26101 gtaaagtagg atggcatttg gtcctaaaac catgagtcca aaactcagtg gaatgataaa
    26161 gaagttaaag attcgactac ctctattaac cagagaaaca taggcttctt tgtctccttt
    26221 ccccagatag taactgagac gaggcacact cactccaatt gcacctgtta caaccccagc
    26281 tataacggtc acaattcgct gagctatggt atagtaacta acgttgacat caatccctgt
    26341 tttaacgagg aagaggcgat ctaaaaaagt gaagagcata ttggcattgg caaagactaa
    26401 catggctgtc agagggagaa agagtggttt aaaatcactt aggtgaattt taacaagttt
    26461 gatgtctctt ttaatccaaa aataactaat caggtagtta atcagcgtcg ataaactcat
    26521 cacaagtgta tagacaacaa tatcgtgttc atttttaaca aataagaaaa tagagaccag
    26581 catcaggata cggatgaagg cagttttgta aaagagaaaa ctgtaatttt ccagagcttc
    26641 attgacccat tcgattgaaa aaatctgggc aatgagttga atccccataa caaggtagac
    26701 ctttttgacg attggattat cagtaaagaa gagaggatag gctaggatat agacagcagt
    26761 ggtcaaaatc gtacaagcga tgcacaaata aaaaagacta gaaaaggttc tgttaagatc
    26821 ttttttgtta tccttgacat tactgatagc ccttaaaccg tagttataga caccataagt
    26881 tgcaaagggc aagaaaaatg acaaaatagt gtcgactgag ttgaagtaac catagtcagt
    26941 tcggtccaag acacgcgcga cataggttcc agttaggatg ggaaaaataa tattcaagac
    27001 acgaattccc atgtaagata gagcatttaa ttttatactt ttcattcaat ttacctcgtt
    27061 tttcattata tcataaagtt agctaataag aaatgaaggg cagtaagtca agtaatcact
    27121 ttgaagtttc aaatcttaaa ttttaagttt tctttaagga aagtatatta ttctgaagga
    27181 ctctaaaatt tcgcagccat ttattagtaa ttgctacaga attcctagtc attactagaa
    27241 atgaactagt ttctttgaat aatagaactg cataattctc ctattctaga aggggaggac
    27301 cagtatttct tttatgatag gactagattg tggtataata gagagaataa gtttttttag
    27361 taagacaaag gagaaaatag atgatttatg caggaattct tgccggtgga actggcacac
    27421 gcatgggaat cagtaacttg ccaaaacaat ttttagagct aggtgatcga cctattttga
    27481 ttcatacaat tgaaaaattt gtcttggagc caagtattga aaaaattgta gttggggttc
    27541 atggagactg ggtttctcat gcagaagatc ttgtagataa atatcttcct cttcacaagg
    27601 aacgtatcat cattacaaag ggtggtgctg accgcaatac aagtattgag aaaatcattg
    27661 aagccattga tgcttatcgt ccgcttactt cagaggatat cgttgttacc cacgattctg
    27721 ttcgtccatt tattacactt cgcatgattc aggacaatat ccaacttgcc caaaatcatg
    27781 acgcagtgga cacagtggta gaagcggttg atactatcgt tgaaagtacc aatggtcaat
    27841 ttattacaga tattccaaat cgtgctcacc tttatcaagg acaaacacct caaacattcc
    27901 gttgcaagga cttcatggac ctttatggat ctctttctga tgaagagaag gaaatcttga
    27961 cagatgcatg taaaatcttt gtgatcaaag gaaaagatgt ggccttggcc aaaggtgaat
    28021 actcaaatct gaagattaca accgtaacag atttgaagat tgcaaaaagt atgattgaga
    28081 aagactagta aaatgattaa tcaaatttat caactaacta agcctaagtt tatcaatgtc
    28141 aaatatcagg aagaggttat tgaccaagag aatcatatcc ttatccgtcc caactacatg
    28201 gctgtctgtc atgcggatca gcgttactat cagggaaaac gtgatcccaa gattttgaat
    28261 aaaaagcttc caatggcaat gattcacgag tcatgtggaa ccgtcatttc tgacccgacc
    28321 ggaacctacg aggttggtca aaaagttgtc atgattccca atcagtctcc tatgcagagt
    28381 gatgaagaat tctatgaaaa ctacatgaca gggacccatt tcttgtctag tggatttgat
    28441 ggctttatga gagagtttgt ttctctccct aaagatcgtg tggtggctta tgatgctatt
    28501 gaagatacgg ttgcagccat tacagagttt gtcagtgtgg gcatgcacgc tatgaatcgt
    28561 ctattgactc ttgctcatag caagcgggag cggatcgccg ttattggaga tggaagttta
    28621 gcttttgtgg ttgccaatat tatcaactat actttgccag aagcagagat tgtggttatt
    28681 ggtcgtcatt gggaaaagtt ggaactcttc tcatttgcca aagaatgcta tattacggat
    28741 aatattcctg aagatttggc ctttgaccat gcttttgaat gttgtggtgg tgatggtact
    28801 ggaccagcta ttaatgactt gattcgctac attcgtcctc agggaacgat tctcatgatg
    28861 ggagttagcg aatataaagt caatctcaat actcgcgatg ccttagaaaa gggcttgatt
    28921 ttggttgggt catctcgttc tggtcgcatt gattttgaaa atgctatcca aatgatggaa
    28981 gtcaagaaat ttgccaatcg tcttaaaaat atcctttatc tagaagaacc tgtaagagaa
    29041 attaaagata ttcatcgtgt ctttgcaacc gatttaaaca cagcctttaa aacagtgttt
    29101 aagtgggaag tataagtact ggaggttaat tgtggagaaa atcattaaag aaaaaatttc
    29161 ttccttactt agtcaagaag aggaagtcct cagtgttgaa caactgggtg gaatgaccaa
    29221 tcaaaactat ttggccaaaa caacaaataa gcaatacatt gttaaattct ttggtaaagg
    29281 gacagaaaag cttatcaatc gacaagatga aaagtacaat cttgaactac taaaggattt
    29341 aggcttagat gtaaaaaatt atctttttga tattgaagct ggtatcaaag taaatgagta
    29401 tatcgaattt gcgattacgc ttgattcaac gtcaatcaag accaagttcg acaaaattgc
    29461 tccaatatta caaactattc atacgtctgc taaggaatta agaggagaat ttgctccttt
    29521 tgaagaaatc aaaaaatacg aatccttgat tgaagaacaa attccttatg ccaactatga
    29581 atctgttaga aatgcagtct tctccttaga gaaaagactg gctgacttag gtgttgacag
    29641 aaaatcttgt catatcgatt tggtgcctga aaactttatc gaatcacctc aaggacgact
    29701 ttatttgatt gactgggaat attcatcaat gaatgatcca atgtgggatt tggctgccct
    29761 ctttttagag tctgaattca cttcccaaga ggaagaaact ttcttatctc actatgagag
    29821 tgaccaaaca ccggtttctc atgaaaagat tgctatttat aaaattttac aagatactat
    29881 ttggagtcta tggactgtct ataaggaaga gcaaggtgaa gattttggtg actatggtgt
    29941 gaatcgttac caaagagctg ttaaaggttt ggcttcttat ggaggttcag atgaaaagta
    30001 aaaacggagt tccttttggc cttctctcag gtattttctg gggcttgggt ctaacggtta
    30061 gtgcttatat cttttcgatt tttacagatt tgtcaccctt tgtggtggct gcagctcatg
    30121 attttttgag catctttatc ttactagctt ttctcttggt aaaagaaggg aaagttcgcc
    30181 tctcaatttt cttaaatatt cgcaatgtca gtgttatcat cggagccttg ctagcaggcc
    30241 ctatcggtat gcaggccaat ctttatgcag ttaagtatat cggaagttct ttagcttcat
    30301 ctgtatcggc tatttaccct gcgatttcag ttctattggc tttcttcttt ttgaagcaca
    30361 agatttcgaa aaatactgta tttgggattg tcttgattat tggagggatt attgctcaga
    30421 cctataaggt tgaacaggtt aattctttct acattgggat tctttgtgct ttggtttgtg
    30481 ctattgcatg gggaagtgag agtgttctta gctcttttgc catggaaagt gaattgagtg
    30541 aaatcgaagc cctcttaatc cgtcaagtaa cttcgttctt gtcctatctt gtgattgtgc
    30601 tcttctctca tcagtcattt actgcagtag ccaatggaca attgctaggt ctcatgattg
    30661 tttttgcagc ctttgatatg atttcctact tggcttatta tatcgctatc aatcgcttgc
    30721 aaccagccaa ggctacaggc ttgaacgtga gctatgtagt atggacggtc ttgtttgcag
    30781 ttgttttctt gggtgcaccg ctagatatgc tgaccattat gacgtcactt gtcgtcattg
    30841 ctggagttta tattattatt aaagaataaa ggagattcgt gtgaaagcca ttatcttagc
    30901 agcgggattg ggaactcgct tgcgtcctat gactgaaaat acccctaaag ccttggttca
    30961 ggttaatcaa aaacccttaa ttgagtacca aattgagttt ctcaaagaaa aaggaatcaa
    31021 tgacatcatc atcattgttg gttatcttaa agaacaattc gattacttaa aagaaaaata
    31081 cggtgttcgc ctcgttttca atgataaata cgctgactac aataactttt actctctcta
    31141 tcttgtaaaa gaagaattgg ccaacagcta tgttattgat gctgacaatt atctctttaa
    31201 aaatatgttc cgcaatgatt tgactcgttc gacttatttt agtgtttatc gtgaagattg
    31261 taccaacgaa tggttcttgg tctatggaga tgactacaag gttcaagaca ttattgttga
    31321 tagcaaggca ggtcgcatcc ttagtggtgt atccttctgg gatgctccaa ctgcagaaaa
    31381 gattgtcagc tttatcgata aggcttatgc aagtggcgaa tttgttgatc tctattggga
    31441 caatatggtt aaggataata tcaaagagct agatgtctat gttgaagaat tagaaggcaa
    31501 tagcatttat gagatcgata gtgtccaaga ctatcgtaaa ttagaagaaa tttttaaaaa
    31561 cgaaaattaa agattccaac atctgacaaa atagtcggat gttttttgat tttttacgaa
    31621 cttttacgaa tagatagatg agtagaaaaa gaaatggagt tatttatgaa aatcacaaac
    31681 tatgaaatct ataagttaaa aaaatcaagt ttgaccaatc aacagatttt gaaagttcta
    31741 gaatacggtg aaaatgttga tcaggagctt ttgttgggtg atattgcaga tatatcaggt
    31801 tgccgtaatc cagccgtttt tatggaacgt tattttcaga tagacgatgc gcatttgtcg
    31861 aaagagtttc aaaaatttcc atctttctct attttagatg actgttatcc ttgggatttg
    31921 agtgaaatat atgatgcgcc tgtactttta ttttacaagg gaaatcttga cctcctgaaa
    31981 ttcccgaagg tagcggtcgt gggcagtcgt gcttgtagca aacagggagc taagtcagtt
    32041 gaaaaagtca ttcaaggctt ggaaaatgaa ctggttattg tcagtggtct ggccaagggc
    32101 attgacacag cagctcatat ggcagctctt cagaatggcg gaaaaaccat tgcagtgatt
    32161 ggaacaggac tggatgtgtt ttatcctaaa gccaataaac gcttgcaaga ctacatcggc
    32221 aatgaccatc tggttctaag tgaatatgga cctggcgaac aacctctgaa atttcatttt
    32281 cctgcccgta atcgcatcat tgctggactt tgtcgtggtg tgattgtagc agaggctaag
    32341 atgcgttcag gtagtctcat tacgtgtgag cgagcaatgg aagaaggacg cgatgtcttt
    32401 gctattcctg atagcatttt agatggacta tcagacggtt gccatcattt gattcaagaa
    32461 ggagcaaaat tggtcaccag tgggcaagat gttcttgcgg aatttgaatt ttaaaaatga
    32521 cctaagctag aattctaaga aaaaatcaat tttaagagaa aatgaaccca acatttccat
    32581 aataaaacgc atattagcaa gtttttaaca cttgataata tgcgtttttt ctaagtggat
    32641 tagtagagta gaggattttt ctcatataat actcttcgaa aatctcttca aactacgtca
    32701 gcttccatct gcaacctcaa aacagtattt tgagctgact tcgtcagtct tatctacaac
    32761 ctcaaagcag tgctttgagc aacctgtggc tagcttccta gtttgcgctt tgattttcat
    32821 tgagtataag ggaaagtata gtgaattgaa ataagatgtg aacaactcta tcaggaaagt
    32881 caaattaatt tatagaaata ttttagcagc caaggtgcac tgttatagat tcaatacact
    32941 ataatttagt gtaattgaga aaggagaaat gattgtgatt gatgttggct aggttatgtt
    33001 caatgattcc taccgtctca aatcttgtca gtaaggaaaa ataaattctt caaaagtaga
    33061 gattacaagg cttgtttaag aaagaattca aagaccttga caaataaaaa taaaatggtt
    33121 attataagaa atggtctaaa atagatgatg atacttttcg aaaatctttt tacgtcagct
    33181 cagctttgcc ttgctgtgtt ttgagcaagc tacggttagc ttccgagttt gattttcatt
    33241 tactagaaat gaaactgatg agagatatca gtagacattt gagtcaggat attatggaaa
    33301 atgataaaaa gagctcgtga gattggcata tcagactact aaagtattga gtttgttagg
    33361 attttagcga ctagttagct gggaaaggaa gatatttgtg acaaataata aactgtattc
    33421 gttgatagaa tttagaaata aaatatatga agaattagaa ctttccagaa gtgatttagc
    33481 gattttacta tgtgccatgc ttatcgcctc tatcggatta aatatggatt cgactcccgt
    33541 gattattgga gccatgttaa tctctccttt gatgacacct attctgggag tggggctctc
    33601 tctagctata tttgatttta aattgttaag aaaatctttt aaaatattag ctattcaaat
    33661 tcttgccagt ctaatagctt caacacttta tttttatctt tctcccattt cgtatgctag
    33721 ttcggagatt gttgctagaa cctctccgac tatttgggat gttctcattg cttttgtagg
    33781 agggatagca ggtattattg gtgctaggaa aaaagagacc aataatattg ttcctggtgt
    33841 tgctattgca accgccttga tgcctcctct ttgtacagta ggttatgcta ttgcttctgc
    33901 taatctaaaa tttatcatag gctcctctta cctattcctc atcaattgta gctttattgt
    33961 cattgcgact tatataggtg ttaggttgat gatggttaag aaacattatt ttaaagataa
    34021 cgaagaagac tctaaaatgc gtaggatttt gcttctagtt gctgttttgc tgatgattcc
    34081 gagtttcatc tctgcaacga ctttagtgag agaaacgttg aaaaaagagt cccttaagaa
    34141 atttatatca gagcagtttc aggggtataa tattttgaaa aaaacctatt ctaaaaagac
    34201 tcatacccta aagctaacca tttcaggaaa ttatttgaca gaagaagaac tcgatatgat
    34261 ttcaagtaag agaggtgact atggtttaag tgatgtttct gttcaagttt cacaattgtc
    34321 tgattcagaa caacttagta aggaagagct ggtggagtat ttcttccagt atatcaagga
    34381 taaggaagca aaagaaaagg agaaagccaa taaatttgat acagagtctg aggagcaata
    34441 atttcttgag aatagctggt ttctctcgtg agtcttctat gtatatcaaa ggaagactga
    34501 ggttttaagt ataaaacttt tcttctatta tagtagctaa gtcttgacag ggttcaaaaa
    34561 atggtttaca ctttataaag tttattactt tgaaaaggtg tgatactgtg gctacggcaa
    34621 caaaaaagaa aaaatcaaca gttaaaaaaa atctagtcat cgtggagtcg cctgctaagg
    34681 ccaagacgat tgaaaaatat ctaggcagaa actacaaggt tttagccagt gtcgggcata
    34741 tccgtgattt gaagaaatcc agtatgtccg tcgatattga aaataattat gaaccgcaat
    34801 atatcaatat ccgaggaaaa ggccctctta tcaatgactt gaaaaaagaa gctaaaaaag
    34861 ctaataaagt ttttctcgcg agtgacccgg accgtgaagg agaagcgatt tcttggcatt
    34921 tggcccatat tctcaacttg gatgaaaatg atgccaaccg tgtggtcttc aatgaaatca
    34981 ccaaggatgc agtcaaaaat gcttttaaag aacctcgtaa gatcgatatg gacttggtcg
    35041 atgcccaaca agctcgtcgg atcttggatc gcttggtagg gtattcgatt tcgcctattt
    35101 tgtggaagaa ggtcaagaag ggcttgtcag caggtcgcgt tcagtccatt gcccttaaac
    35161 tcatcattga ccgtgaaaat gaaatcaatg ccttccagcc agaagaatac tggacagttg
    35221 atgctgtctt taaaaaggga accaaacaat ttcatgcttc cttctatgga gtagatggta
    35281 aaaagatgaa actgaccagc aataacgaag tcaaggaagt cttgtctcgt ctgacgagta
    35341 aagacttttc agtagatcag gtggataaga aagagcgtaa gcgcaatgct cctttaccct
    35401 ataccacttc atctatgcag atggatgctg ccaataaaat caatttccgt actcgaaaaa
    35461 ccatgatggt tgcccaacag ctctatgaag gaattaatat cggttctggt gttcaaggtt
    35521 tgattaccta tatgcgtacc gattcgactc gtatcagtcc tgtagcgcaa aatgaggcgg
    35581 caagcttcat tacggatcgt tttggtagca agtattctaa gcacggtagc aaggtcaaaa
    35641 acgcatcagg tgctcaggat gcccatgagg ctattcgtcc gtcgagtgtc tttaatacac
    35701 cagaaagcat cgctaagtat ctggacaagg atcagctcaa gctatatacc cttatctgga
    35761 atcgttttgt ggctagccag atgacagcgg ccgtttttga taccatggct gttaaattgt
    35821 ctcaaaatgg agttcaattt gctgccaatg gtagtcaggt taagtttgat ggttatcttg
    35881 ccatttataa tgattctgac aagaataaaa tgctaccaga tatggctgtt ggagatgtgg
    35941 tcaaacaggt taatagcaaa ccagagcaac atttcaccca accgcctgcc cgttattctg
    36001 aagcaacact gattaaaacc ttagaggaaa atggggttgg acgtccatca acctatgcgc
    36061 caaccattga aaccattcag aaacgttatt atgttcgcct ggcagccaaa cgttttgaac
    36121 cgacagagtt gggagaaatt gtcaataagc tcatcgttga atatttccca gatatcgtaa
    36181 acgtgacctt cacagctgaa atggaaggta aactggatga tgtcgaagtt ggaaaagagc
    36241 agtggcgacg ggtcattgat gccttttaca aaccattctc taaagaagtt gccaaggctg
    36301 aagaagaaat ggaaaaaatc cagattaagg atgaaccagc tggatttgac tgtgaagtgt
    36361 gtggcagtcc aatggtcatt aaacttggtc gttttggtaa attctacgct tgtagcaatt
    36421 tcccagattg ccgtcatacc caagcaatcg tgaaagagat tggtgttgag tgtccaagct
    36481 gtcatcaggg acaaattatt gagcgaaaaa ccaagcgtaa tcgccttttc tatggttgca
    36541 atcgctatcc agaatgtgaa tttacctctt gggacaagcc tgttggtcgt gactgtccaa
    36601 aatgtggcaa cttcctcatg gagaaaaaag tccgtggtgg tggcaagcag gttgtttgta
    36661 gcaaaggcga ctacgaggaa gaaaagatta aataagagga ggggcccgaa agtaaatttc
    36721 aggctccttt tggttagaac ttgacaaaat acatcatttt atgcgaaact agaagaagat
    36781 tattttaact aggagaagtt atgcgtctta tctatctgat aattggtttt ttatcactgg
    36841 ccttggctat tgttggggtt gttttaccct tgttgccgac aacgcctttc cttttgttgt
    36901 ctattgcttg tttctccaga agttccaagc gtttcgaaga ctggctttat cataccaagc
    36961 tctatcaaac atatgtagct gattttcgcg agactaagtc tattacgcgt gaacgaaaga
    37021 aaaaaatcat cgtctctatc tacgtcttga tgggaatttc tatttatttt gcacctcttt
    37081 taccagtcaa aatcggtctg ggtgctttga ccatctttat cacttattat cttttcaagg
    37141 tcattccaga caaagaatag ttaaaacagt agttatttgc cttgataaaa ttgaaagcat
    37201 attcataata atatgatata ataaatttga agtaatattc aaggagaatc aaatgattta
    37261 cgaattttgt gctgaaaatg tgactttact tgaaaaagcg atgcaggctg gagctcgtcg
    37321 gattgaactc tgtgataatc tagcagttgg tgggacaaca cccagctatg gagtgactaa
    37381 ggcagcggtt gaactggcag ctaactacga tacaaccatc atgaccatga ttcggccacg
    37441 tggtggtgac tttgtctata atgacctaga aattgctatc atgctagaag acattcgttt
    37501 gactgctcag gctggaagtc aaggggttgt atttggaact ttaactgctg ataaaaagtt
    37561 ggataagcct aatctggaaa agttaattgc tgcatcaaaa ggaatggaaa ttgtctttca
    37621 catggccttt gatgaactaa gtgatgaaga tcaaccggaa gctattgact ggctcagtca
    37681 agccggtgtc actcgtatcc taactcgtgc tggtgtgtct ggcgactcct tagaaaaacg
    37741 ttttgttcac tatcacagaa ttttggagta cgctaaaggt aaaattgaaa ttctaccagg
    37801 tggggggatt gaccttgaaa accgtcaaac ctttatcgac caggtggggg taacacaatt
    37861 gcatggtact aaggttgttt tttaaaaaat agaaaggaac tgctagcttt gggtagcagt
    37921 tttcacttat gtttgaaatt tttaaatcct atcaatttaa tcaagaaaag gctcatgatt
    37981 atggttttat agaaaatagc gaagtctgga catatagttg ccagattttg caaggtgact
    38041 ttgtcatgac tgtgtccatc actgctgata atgtgaactt tcaagtcttt gaccaagaga
    38101 ctggtgacct ctatcctcac gttcatatgg aaagcatgag gggaagtttt gtcggaaatg
    38161 tccgtgaggc ttgtctggag attctttacc agattcggaa ggcttgtttt gatgtgcaag
    38221 attttatctg tcatcagact aagcgtatca tgactcaagt tcaggaaaag tatggaaacc
    38281 agttggagta tctgtgggaa aaatcgcctg atacagctgt attgcgccat gaaggcaatc
    38341 aaaagtggta tgccgtcttg atgaaaatct cttggaataa gctggaaaag ggcagagaag
    38401 gacaagtgga agcagtcaac ctcaagcatg accaagtagc taatttgctt tcacaaaagg
    38461 ggatttatcc agccttccat atgagcaagc gctactggat tagtgtgtcc cttgatgata
    38521 ctttatcaga tgaagaagta ctggaattga tagaaaaaag ttggaactta acctctaaaa
    38581 aatgaaatat tttaataatt ttcatgaact ttcaattagc taaatattct ttactgaaga
    38641 aattttcaga aaatatagga tttaccacac cagaggaata tggtgccatc ttcaaatacc
    38701 tgattgagaa tgtcaagacg gatcgtcaga tcatctattc gcctcactgt catgatgacc
    38761 tcggaatagc agtggcaaat agccttgctg ctgtcaagaa tggtgcagga cgtgttgaag
    38821 agactatcaa tggtattagg gagcgagctg gaaatgctgc tttggaagaa attgcagtgg
    38881 ctctcaatat tcgccaagat tactaccaag tagaaaccag tattgtccta actgagacca
    38941 tcaatacgtc agaaatggtt tctcgcttct ctggtattcc agttcctaaa aacaaagccg
    39001 tcgttggtgg caataccttc tcccacgaat ctggtattca ccaagatgga gtccttaaaa
    39061 atcctctcac ttatgagatc atcacacctg aattggttgg tgttaagatt ccgcttggaa
    39121 aattatctgg tcgccatgct tttgttgaga aactgagaga attggcccta gattttacag
    39181 aagaggatat caaaccactc tttgctaagt tcaaggcact ggtcgataag aagcaagaaa
    39241 tcacagatgc agatattcga gctttggtag ctggaaccat ggttgaaaat ccagaaggct
    39301 tccactttga tgatttacaa cttcaaactc atgcagataa tgacattgaa gcgctcgtta
    39361 gcctagccaa tatggatggt gagaaagtcg aatttaatgc gacagggcaa ggttccgttg
    39421 aagcaatctt taatgctatc gataagttct ttaaccaatc tgttcgtttg gtgtcctaca
    39481 ctatcgatgc ggtaacagat ggaatcgata cccaggaacg ggttttggtc actgttgaaa
    39541 acagagatac agaaaccatc ttgaatgcag cagggcttga ttttgatgtg ttgaaggctt
    39601 ctgctattgc ctatataaac gctaatacct ttgttcaaaa agagaatgca ggtgagatgg
    39661 gacgcagtgt ttcttaccac gatatgccta gtgtgtaaag gagaaggcta tggcaaagaa
    39721 aatagtagct ctagcaggag acggaattgg cccagaaatc atggaggctg gtttagaagt
    39781 tctggaggct ctagctgaaa aaacaggttt tgactatgag attgacagac gaccgttcgg
    39841 aggtgcagat attgatgcag caggatctcc cttacctgat gaaaccctta aggcaagtag
    39901 ggaagcagat gctatcctac tagtagctat cggtagtcct cagtatgatg gagtagcggt
    39961 tcgccctgaa caaggcctga tggctctccg taaggaactc aatctttacg ctaatattcg
    40021 tcctgtaaaa atctttgaca gtctcaagta tttgtcacca ctcaaaccgg aacgaatttc
    40081 tggtgtagac tttgtcgtgg tgcgtgaatt gacaggcgag atttactttg gagatcatat
    40141 tcttgaagag cgcaaagcgc gtgatatcaa cgactatagc tatgaggaag tggagcggat
    40201 tattcgcaaa gcctttgaaa ttgcaagaaa tcgcagaaaa atcgttacta gtatcgataa
    40261 gcaaaatgtt ctagcgacct caaaactctg gcggaaagta gctgaggaag tcgcacagga
    40321 tttcccagat gtaaccttgg aacaccagct ggtagactca gctgctatgc ttatgattac
    40381 caatcctgct aagtttgatg ttattgtaac ggagaatctt tttggagata ttttatctga
    40441 tgaatcaagc gtcttatctg gtacacttga ggttatgcca tcagccagtc attctgaaaa
    40501 tggaccaagt ctctatgaac ctattcacgg ttcagcacct gatattgcag gtcaaggaat
    40561 tgccaatcct atttccatga ttttattagt tgtcatgatg ttgagagata gtttcggacg
    40621 ttatgaggat acagagcgta tcaaacgtgc tgttgagaca agtctggcgg caggaatttt
    40681 aacgagagat ataggaggtc aggcttcaac aaaggaaatg atggaagcta ttattgcaag
    40741 gttatgaagt tagacgaaaa aattactcta gtccttttga tttggaatgt catcattttc
    40801 ttgatttatg gcattgacaa attcaaggca agaagaagag cttggcgcat cccagagaaa
    40861 atcttactca ttttagccct tacttgtggt ggttttgggg cctggttagc tggaatcact
    40921 tttcaccaca agactcgaaa atggtacttt aaaacagttt ggtttcttgg gatggtgacc
    40981 acactagtag ccttatattt tatttggagg taatggatgg tagggtcttc gagggaacac
    41041 gctgcttggg ctctagcgga ctatggtttt aaggtcgtga ttgcaggatc tttcggtgac
    41101 attcattaca ataatgaact caataatggc atgttgccaa tcgttcagcc tagagaggtt
    41161 agagagaaac tagcccagct aaaaccaacc gaccaggtaa ctgtggactt ggaacaacaa
    41221 aaaatcatct caccagttga agaattcacc ttcgagatag atagcaagtg gaaacataaa
    41281 ctcctaaata gtttggatga tatcggtatt accttgcagt atgaagagtt gattgctgct
    41341 tatgaaaaac aacgaccagc ctactggcag gattagaaaa aatagaaaag gaaatatagt
    41401 aaactgaaat aagatgtaaa caaatgaatt ggagcttaac atccatttcc agcaattttt
    41461 tagaaactac agtggactat tctggattca acacattata aaattatgac aaaacacatt
    41521 cacaagaagg ctacgacatt ttaaaaggtg agggcggatg tatcgtttgc cctactaaag
    41581 ttggttacat tatcatgacc agcaacaagg caggacttga gcgtaagttc gcagccaaag
    41641 aacgtaagcg taacaaacca ggtgttgttc tctgcggtag catggatgaa cttcgcgctt
    41701 tagcgcaact caacccagaa attgaagcat tctactaaaa acattggatg aagatattct
    41761 tcttggttgt atccttcctt ggaaaccaga agcctttgaa aaactcaaag catacgggga
    41821 tggccgtgaa gaacttatga ctgatgtacg tggtactagc tgttttgtta tcaagtttgg
    41881 aaaagcaggt gaacaattgg ctgccaagct ttgggaagaa ggtaaaatgg tctacgcctc
    41941 atatgcttca atgacaaaac gattgaaact cgctatgaga gcaaggtgta atggtgtcta
    42001 tggtcgataa ggacggcaaa ctcatcccag aacaaggagg agcacgttca acttcaccag
    42061 caccagttgt gatccgtaaa gggcttgaca ttgataaaat catgatgcac ctgtcagata
    42121 cttttaactc atgggactac tgtcaggttg agtattatta agataaaaaa agaagtctag
    42181 tgttatgaga tattaaagct cctaacactg gactttttgt ttagaatttc ttttcttttt
    42241 ctataggata tggtattcta tgtagaaaat atatgttaat aagtaatgcc aatatttaaa
    42301 catcattagt aaaaggagtt agattgatga ataaaagaaa agttagttta gaagattttt
    42361 ataaatggta tagtctaaat aaagaagagt tattaaataa ggcaactgtt ggtgaaaagt
    42421 ttaatgataa attaaaagaa gagtttctcc aggaatggcc tttggatagg attttaacaa
    42481 tgtcaatcga tgaatatgta ataggaaagg gacagcaaaa taagtcttta tgctacgctc
    42541 ttgagaaggg aaaatacaaa aatctatttc ttggaatttc tggtggctca gcttcaaaat
    42601 ttggtattta ttggaataaa aaaacaaaca aatataaaga tcaagctaat aatgagattt
    42661 cagagttgga tcagcgattt tcaaaattaa aatcagattt gtatgaaatt atcaaagaag
    42721 gtattcgttt taactttgaa aatcctattt ttgatatgaa aagatcaaca aatgaattta
    42781 ttggtcgttc tgctatggtg acaaaattac tttgtatcta tactgaggga gatcctttct
    42841 ttggtgtaaa tattaatagt cagaaagaat tttggaacca ctttgtttct cagacaaatc
    42901 aaggtggacc ttatctgcaa aatcataaaa taattgaact ggtgtccaaa acttatcctg
    42961 agttggagcc atcgaaatta ggaactatgc tttttgagta ttctaagctt tttatggaaa
    43021 ataaggaaga caatagtaca atggattcat caaacaattt tagtcatcaa ttaactcaat
    43081 ctctattaaa gtctccaaac cttatccttc gtggtgctcc tggcacagga aagacttatc
    43141 ttgctaaaga aattgccaaa gaattaacgg atggcaacga agaccaaatc ggatttgtac
    43201 aatttcaccc atcctatgat tatacggatt ttgtagaagg tttaagacca gtatcaaatg
    43261 gggatggagc tattgagttt aggctacagg acggtatttt taaagatttt tgtcagaaag
    43321 caaaagaaac ccaattgatt ggaagacaag ataattttga tgaggcttgg gattcttact
    43381 tagaatatat aaatgttgct gaagaaaaag aatatataac aaaaacatct tacttatctg
    43441 ttaatagtag acaaaatttg tcagtaaatt atgatagtgg tgttccagga tggtcactac
    43501 ctagcaaata tgtttacgag ttgtataaag ataaaaatta taataagcaa gaatactaca
    43561 aaagtggtgg aaaaactgtc ctagaaacat tgagaaagag atttggtttg aaagactatg
    43621 tttccccaac agaaattgat actgataaga aattcgtctt catcatcgat gaaatcaatc
    43681 gtggggagat ttctaagatt tttggcgaac tctttttctc tatcgaccct ggctatcgtg
    43741 gtgaaaaagg aagtgtttct acccaatatg caaatctaca cgaaactgat gaaaagttct
    43801 atatccccga aaatgtttac atcatcggaa ctatgaatga tattgatcgt tcagtggata
    43861 cctttgattt tgctatgcgt cgtcgttttc gttttgttga agttactgcc gagggtcaag
    43921 ttggcatgtt ggataaagag ctgaatatcc atgcagaaga agcaaaaatt cgtctaagaa
    43981 acttgaacgc tgctatcgaa aatgttcagg aattaaacag tcattatcat attggaccaa
    44041 gttattttct taagttgaag gatgtagatt ttgactatga attactctgg tctgattata
    44101 ttaagcctct cctagaagac tacttgcgag gttcttatga tgaggttgaa actttggaaa
    44161 ctttgaaaaa agcatttgaa ctgacaaata atgagcaaaa agatcaggca gtagctgatg
    44221 acaatgaagg cgatgaaaac gatgatgcgg attactgata atcaacacaa gattattaaa
    44281 gaaaaatttg ttgaagaata tcctaaacta agcaatcttc ttttagacag aaccttggaa
    44341 agtctatccc aagatgaacg tattttcatt tttccaaatg atttgactca tactcctgat
    44401 ttggataagg accaaaagat ttttgaaaca gtcaatcaga aaatcaagac agggaacgtg
    44461 attggttttc ttggatatgg tcaggaaaga ttaacgattt cctcacgatt ttctgatgag
    44521 agtaatgacc attttttgca ttatctctta aacaaggttc ttcatatcaa tctcactagt
    44581 ttagatgttg ctttgtctcg tgaagagagg ctttatcaac ttttgatgta tctcttcccc
    44641 aagtatctac aagctgctat tcgaaaaggt ctttataagg aataccagag attttctcat
    44701 aacgacagtc atgttaaggg agtgattgat gtaagaaacc atctcaagaa aaatcttcct
    44761 ttcacgggaa atattgccta cgcaacgaga gagttcacct atgataatcc cctcatgcag
    44821 ttggtccgtc acactattga atacattaag aatcagaaaa gcattggtca aggggtacta
    44881 gataatctct caactagtcg tgaaaacgta tctgaaatcg tgcgtgtaac gccctcttat
    44941 aaactagctg atcgtgctaa gattattcgg ggaaatcaat ctaaacctat acgtcatgca
    45001 tactttcacg agtacagaaa cttacaagaa ctttgtctga tgatcctaaa ccaagaaaag
    45061 cacggtttag ggtatcaaga tcaaaaaatc tatggtattc tctttgatgt tgcctggctt
    45121 tgggaagagt atgtttacac cttgttgcca aaaggttttg tacatcccag aaataaggat
    45181 aagacggatg gaatttcagt attttctgtt gggaaacgaa aagtatatcc agatttttat
    45241 gacagagaac gaaagattgt tctagatgca aaatataaaa aactggaatt gactgaaaaa
    45301 ggaatcaacc gtgaggactt attccagctg atttcctatt cttatatttt aaaagctgag
    45361 aaggctggac tgatttttcc tagtatggag cagtcagtaa atagtgaaat aggaaaagta
    45421 gctggctatg gagctcaatt gaagaagtgg tctattcgaa tccctcagaa tgcctcattc
    45481 tatagtacat tttgtaaaat gatggaaaat tcagaagaaa attttaaagc gattattgat
    45541 gaagaagtgg ggagaaaata atttcccctc tttcttttat ttttaacaca agtaaaaccc
    45601 gaacgatata ttttaattca taaaataatt tgacaaaaac tgtactttga tttataataa
    45661 attaaggaaa cgtcggaaaa ggcgtagtga tgcaagagca taggtaggtc attacaaaag
    45721 aaacgagaca tcgatatgtt aaatgaattt ccaatttttg attacgaaga tattcaattg
    45781 attccaaata aatgtgtcat taaaagccgt gcagaagcgg atacaagtgt cactttagga
    45841 aatcacacct ttaaactacc tgttgtgcca gcgaatatgc agacgatttt ggatgaaaat
    45901 gtagcagagc aactggctaa aggtggttac ttctacatta tgcaccgttt tgatgaggca
    45961 ggacgcattc cttttattaa acgaatgcac aatcaagggc tcattgcttc tatctctgtc
    46021 ggtgttaagg attatgagta tgattttgtt agccagctca aggctgatac tcctgagtat
    46081 atcactattg atattgctca tggtcatgcg gatagcgtga tttctatgat tcaacacatc
    46141 aagaaagaat tgccagatac ctttgtcatt gctggaaatg tgggaacacc agaagctgtg
    46201 cgtgaattgg aaaatgctgg tgcggatgct actaaggtcg gaatcggtcc tggtaaggtt
    46261 tgtatcacca aggttaagac tggttttggt acaggtggtt ggcagttggc tgctctacgc
    46321 tggtgtgcca aggctgcgcg taaaccgatt atcgctgatg gaggaattcg tactcacggt
    46381 gatattgcca agtctatccg cttcggtgct agcatgatca tgattggttc cctctttgca
    46441 ggacacattg aaagtccagg gaaaacgatt gaagtcgatg gtgaacagtt caaagaatat
    46501 tatggttcag cctcacaata tcaaaaaggt gcttacaaaa atgtggaagg caaacgtatc
    46561 ttgcttcctg ctaaaggtca tctgcaagac actttaactg agatggaaca agaccttcaa
    46621 agtgctattt cttatgcagg tggacgtcag gttgctgacc ttaaacacgt tgattatgtg
    46681 atcgtgaaaa actccatctg gaatggggat gcttcccact aagacggggt ctttgaccaa
    46741 aaaacttgtt attagagcaa atttctgtta taataaaaca agtttccacc cttagtgtaa
    46801 tggatatcac gtaagattcc ggttcttgag atgggggttc gattccctca gggtggatgt
    46861 aaacatccta aaaagccttt aatagggctt ttttctttat cctgacccaa atttgccgct
    46921 aaaactgaga atctctgtct aaagaattcc caaatgcttt ccagtcccgt tttagagtga
    46981 ctcagggggc tttttttgat ataataaaaa ggactattat cagttagaaa gaggttggta
    47041 tgaaagaatt acaaactgta ctaaagaatc attttgcaat cgaatttgca gacaaaaatt
    47101 tactggaaac tgcctttact catacgagtt atgccaatga gcaccgcctc ttaaaaattt
    47161 cacacaatga acgcttggaa tttttaggag acgctgttct acagttattg atttcagaat
    47221 atctatataa aaaatatcct aaaaagcctg aaggtgacct atcaaaactc cgtgctatga
    47281 ttgtccgtga ggagagttta gctggttttg cgcgtgattg ccagtttgac cagtttatca
    47341 agttgggtaa aggggaagaa aaatctggtg gtcgcaatcg tgacaccatt cttggtgatg
    47401 cctttgaagc ctttcttggt gcccttcttt tggataagga tgtggccaag gtcaaggaat
    47461 ttatctatca agtcatgatt cctaaggttg aagcaggcga atttgagatg attacagact
    47521 ataaaaccca tctccaagag ttacttcagg tcaatggtga tgtggctatt cgttatcagg
    47581 tgatttctga aacagggcct gctcacgata aggtctttga tgtagaagtt cttgttgaag
    47641 gtaagagcat cggtcaaggc caaggtcgtt ctaagaaatt agcagagcag gaagctgcca
    47701 aaaatgccgt tgagaagggg ctggattcat gtatttaaag gaaatcgaaa ttcaggggtt
    47761 caagtctttt gctgataaga ccaaggtcgt ttttgaccaa ggtgtgacgg cagttgttgg
    47821 acccaatgga tctggaaagt ccaatattac agaaagtctg cgttgggctt tgggggagtc
    47881 tagtgtcaag agtctccgtg ggggcaagat gccggatgtc atctttgctg gaaccgaaag
    47941 tcgcaaaccg ctcaattatg cttctgtagt tgtgactctg gataatcatg acggatttat
    48001 caaggatgca ggtcaagaaa tcagggtgga acgccatatc tatcgtagtg gagatagcga
    48061 atacaagatt gacggcaaga aagtccgtct gcgtgatatt catgacctct tcttggatac
    48121 tggattggga cgagattcct tctctattat ttcccaaggg aaggttgagg agatttttaa
    48181 ttccaagcct gaggaacgac gagctatttt tgaagaagct gcaggagttt taaaatacaa
    48241 gactcgcaga aaagaaactg agagtaaact gcaacaaact caggataatc tagaccgctt
    48301 agaggacatt atctacgagt tggataatca aatcaagcct cttgagaagc aagctgagaa
    48361 tgcctgtaag tttttagact tggaaggaca acgtaaggct atttatttag acgttctggt
    48421 tgctcaaatc aaggaaaata aggcagaact agagtcgaca gaagaagagc tggctcaggt
    48481 tcaagaactc ttgatgagtt attaccaaaa gcgtgaaaaa ttagaagaag aaaatcaaac
    48541 tcttaaaaag caacgccaag atttacaggc tgaaatggcc aaagaccaag gcagtttgat
    48601 ggacttgact agtctgatta gtgatttaga aagaaaatta gccctatcga aactggagtc
    48661 cgagcaagtg gccttgaatc aacaggaggc acaagctcgt ttggctgctt tggaggataa
    48721 gagaaattca ctcagcaaag aaaagtctga taaagaaagc tctttagctc tgttagaggg
    48781 aaatctagtc caaaataatc aaaaactcaa tcgtttagaa gctgaattgc tggctttctc
    48841 agacgatcct gatcagatga ttgagctctt acgtgaacgc tttgtagctc ttttacaaga
    48901 agaagcggat gtctcaaacc agttgacccg tattgagaat gagttggaaa atagtcgtca
    48961 gctttctcaa aaacaagcag atcaactaga aaagctgaaa gagcaattag ctatagctaa
    49021 agagaaggct agtcagcaaa aggaagagct tgaaactgcc aaggagcagg ttcagaaatt
    49081 attggctgac taccaagcta ttgccaagga gcaagaggag cagaaaactt cctatcaagc
    49141 tcaacaaagc caactctttg accgtctgga taatctcaaa aacaagcagg ccagagctca
    49201 aagtttggaa aatatcctga gaaatcatag taacttttat gcaggtgtta agagtgttct
    49261 ccaagaaaaa gatcgcctag gtgggattat tggtgcagtc agtgagcatc tgacctttga
    49321 tatgcattat caaactgccc tagaaattgc gcttggagcg agtagtcagc acattattgt
    49381 agaagatgag aatgcggcaa ccaaggctat tgacttcctt aaacggaaca gagccggtcg
    49441 tgcaaccttt cttcctttga ccactattaa ggcgcgtacg atttctagtc agaaccaaga
    49501 tgctatcgct gtaagcccag gtttccttgg gatggcagat gagttggtga cttttgatac
    49561 tagactggaa gccattttca agaacttgct agctacgacg gctatctttg ataccgtaga
    49621 acatgcgcgt gaagctgctc gacaagttcg ttatcaggtt cgtatggtga cattggatgg
    49681 gacagaatta cgcacgggtg gttcctatgc gggtggtgcc aatcgccaaa ataacagtat
    49741 tgtcatcaag ccagaactgg agcaattaca aaaagaaatt gctgcagatg aagcaagctt
    49801 gggttcagaa gaagcggctt tgaagacctt gcaagaccag atggctgcat tgacagaaag
    49861 attagaagcc atcaaatctc aaggagagca ggcacgtatt caggagcaag gcttgtccct
    49921 cgcttatcag caaactagtc agcaagttga agaactggaa actctttgga aactccaaga
    49981 agaggaaata gatcgtcttt ctgagggaga ttggcaagcg gataaggaaa aatgtcaaga
    50041 gagccttgct actatcgcca gtgaaaagca aaatctggaa gctgagattg aagaaattaa
    50101 gtctaataaa aacgccatcc aagaacgcta tcaaaatttg caggaagagg tggcgcaagc
    50161 tcgcttgctt aagacagaac tgcaagggca aaaacgttat gaagtagctg atattgagcg
    50221 tttaggcaag gaattggaca atcttaatat cgaacaagaa gaaattcagc gcatgctcca
    50281 agaaaaagtt gacaatcttg agaaggttga tacagaattg ctcagtcaac aggcggaaga
    50341 atccaaaact cagaaaacaa atctccaaca aggtttgatt cgcaagcagt ttgagttgga
    50401 tgatatagaa ggtcaactgg atgatattgc cagtcacttg gatcaagctc gccagcagaa
    50461 tgaggagtgg attcgcaagc aaacacgtgc tgaagccaag aaagaaaagg tcagcgagcg
    50521 cttgcgccat ctacaaaatc aattaacaga ccagtaccag attagctata ctgaagcact
    50581 agaaaaggca catgaattgg aaaacctcaa tctggcagag caagaggtgc aggatttaga
    50641 gaaggctatt cgctcattgg gacctgtcaa cttggaagct attgaccagt acgaagaagt
    50701 tcacaaccgt ctggactttc taaatagtca gcgagatgat attttgtcag cgaaaaatct
    50761 gctccttgaa accattacag agatgaatga tgaggtcaag gaacgcttta aatcaacctt
    50821 tgaagctatt cgtgagtcct ttaaagtgac cttcaagcag atgtttggcg gaggtcaggc
    50881 agacttgata ttgactgagg gcgacctttt aacagctggt gtggagattt ctgttcaacc
    50941 tccaggtaag aaaatccagt cgcttaacct catgagtggt ggtgaaaaag ctctatcggc
    51001 tcttgccttg cttttctcca ttattcgtgt caagaccatt ccttttgtca tcttggatga
    51061 ggtggaagct gcgctggatg aagccaatgt taaacgtttt ggggattacc tcaaccgctt
    51121 tgacaaggac agccagttta tcgttgtaac ccaccgtaag ggaaccatgg cagcggctga
    51181 ttccatctat ggagtgacca tgcaagaatc gggtgtttca aagattgttt cagttaagtt
    51241 aaaagattta gaaagtattg aaggatgaca attaaactag tagcaacgga tatggacgga
    51301 accttcctag atgggaatgg acgctttgat atggatcgtc tcaagtctct cttggcttcc
    51361 tacaaggaaa aagggattta ctttgcggtg gcttcgggtc ggggatttct gtctctggaa
    51421 aaattatttg ctgatgttcg tgatgacatt attttcatcg cggaaaatgg cagtttggta
    51481 gagtatcaag gtcaggactt gtatgaagcg actatgtctc gtgactttta tctggcaact
    51541 tttgaaaagc tgaaaacgtc accttatgta gatatcaata aactgctctt gacgggtaag
    51601 aagggttcat atgttctaga tacggttgat gagacctatt tgaaagtgag tcagcattat
    51661 aatgaaaata tccaaaaagt agcgagtttg gaagatatca cagatgacat tttcaaattt
    51721 acaaccaact tcacagaaga aacgctagaa gctggtgaag cttgggttaa tgaacatgtc
    51781 cctggtgtta aggccatgac aactggcttt gaatctattg atattgttct ggactatgtc
    51841 gataagggtg tagctattgt tgaattagct aaaaaacttg gtatcacaat ggatcaggtc
    51901 atggcttttg gagacaatct taatgactta catatgatgc aggttgtggg acatcctgta
    51961 gctcctgaaa atgcacgacc tgaaatttta gaattagcaa agactgtgat tggtcaccat
    52021 aaggaacggt cggttatagc ttatatggag ggcttataat ggcagatata aaattgattg
    52081 cattggactt ggacgggacc ttgctgacta ctgataaaag gctgacggat cgtaccaagg
    52141 aaaccttgaa agctgcgcgt gatcgtggta tcaaggtcgt attgacaact ggtcgtccct
    52201 taaaagccat ggacttcttt ctccatgagt tagggactga cggccatgaa gatgagtata
    52261 ccattacttt taatggtgga ttagttcaga aaaatacagg agaaatcctt gataaaacag
    52321 tcttttcata tgatgatgtg gcacgtttgt atgaagaaac agagaaatta tcactgcctc
    52381 ttgatgccat ctcagaagga acagtttatc aaatccaatc ggaccaagaa agtctttatg
    52441 ccaaattcaa tccagctttg acctttgttc cagtggactt tgaagactta tctagtcaaa
    52501 tgacctacaa caaatgcgtg actgcctttg ctcaagaacc cttggatgca gccattcaga
    52561 agatttctcc agaattgttt gaccaatatg aaatctttaa atcacgtgaa atgttgctag
    52621 aatggtcacc aaagaatgtt cataaagcaa caggtttggc aaaactaatc agccatcttg
    52681 gaatcgacca aagtcaagtg atggcttgtg gtgacgaggc caatgacctc tctatgattg
    52741 aatgggcagg tcttggtgtt gctatgcaaa acgctgtttc tgaagtaaag gcagccgcaa
    52801 atgtagtgac gccgatgacc aacgatgagg aagctgtcgc ctgggctatc gaagaatatg
    52861 tgctaaagga gaactaagat atgggattgt ttgaccgtct attcggaaaa aaagaagaac
    52921 ctaaaatcga agaagttgta aaagaagctc tggaaaatct tgatttgtct gaagatgttg
    52981 atcctacctt cacagaagtt gaggaagttt ctcaggaaga agcagaggtt gaaattgttg
    53041 aacaagctgt gttccaagaa gaggaaatcc aagacacagt tgaagaaagt ctggatttag
    53101 agccagttgt agaagtttct caaaaagaag tcgaagaatt tccacactca gaagaaggga
    53161 atactgagtt tctagagact atagaagaaa ataattctga agttcttgaa gcagaaaggc
    53221 ctcaagcaga agaaaccgtt caggaaaaat atgaccgcag tcttaagaaa actcgtacag
    53281 gtttcggtgc ccgcttgaat gccttctttg ctaacttccg ctctgttgac gaagaatttt
    53341 tcgaggaact ggaagaactg ctgattatga gtgatgttgg tgtccaagtc gcttctaact
    53401 taacggagga actacgttac gaagccaagc ttgaaaatgc caagaaacct gatgcacttc
    53461 gtcgtgtcat cattgagaaa ttggttgagc tttatgaaaa ggatggtagc tacgatgaaa
    53521 gcatccactt ccaagataac ttgacagtta tgctctttgt tggtgtgaat ggtgttggga
    53581 aaacaacttc tatcggaaaa ctagcccacc gctacaaacg agctggtaag aaggtcatgc
    53641 tggttgcagc agataccttc cgtgcgggtg cagtagctca gctagctgaa tggggccgac
    53701 gagtagatgt tccagtagta actggacctg aaaaagctga tccagccagc gtggtctttg
    53761 atggtatgga acgtgccgtg gctgaaggta tcgatattct catgattgat actgctggtc
    53821 gtctgcaaaa taaggataac cttatggctg agttggaaaa gattggtcgt attatcaaac
    53881 gtgttgtgcc agaagcacca catgaaacct tcttggcact tgatgcatca acaggtcaaa
    53941 atgccctagt acaggccaaa gaattttcga aaatcacacc tttaacggga attgttttga
    54001 ctaagattga tggaactgct cgaggaggtg tggttctagc cattcgtgaa gaactcaata
    54061 ttcctgtaaa attgattggt tttggtgaaa aaatcgatga tattggagag tttaactcag
    54121 aaaactttat gaaaggtctc ttggaaggct taatctaatc agaagcaaaa atcctgcaag
    54181 gtacaaactt gcaggatttt tttattcgaa acgaccatct tgacgatagg cgatatctgg
    54241 ttgccaagtc catttggcat cgaatttttc aagtaggtca aagctggctt gaggtcccat
    54301 gcttccagct ttatagtcat gaagtggggc accattttcg gcccagagct cttcaatacg
    54361 gtcaatcaac ttccatgacg caccaacttc atcccagtgg ctaaagttag ttgagttgtt
    54421 atttaggaca tcataaatca atttttcgta tggttctgga gaagcaccag ttgcagtcgc
    54481 atctgtacgg taatcaagtg agttaggagc caagttaaat tcttctccta cttgcttccc
    54541 atttaggcta agagagaagc cttctgttgg ttgaatatag atggtcaaaa tatttggagc
    54601 aagtggttct ccaaagatag aatccatttg tttaaagacg atgttgacat gggttccttt
    54661 ttcagtcagt cgtttacctg tacggaaaaa gaaaggaaca ccacggaatc gatcgctgtc
    54721 tacaaagaag gcacctgatg taaaggtttc agttgttgat tctggattca catttggctc
    54781 gctacgataa gagatgtatt tcatgccatc aatcttacca gagcggtatt gcccacggat
    54841 aaagtgttct ttgagttctt catcagttgg atgatagagg tttttaaaga ccttaatctt
    54901 ttcagcacga atctcgtctt ttgtgaagct tgctggtttg tccatggcga ggagcgaaag
    54961 aagttgtaga gtgtggtttt ggaccatgtc acggagggca ccggattggt catagtagcc
    55021 accacgttct tctacaccca agcgctccgc aaaggtaatt tgaacattgt cgataaaatc
    55081 cttgttccaa acgttttcaa aaatcaagtt tgcaaagcga actgcaaaga tgctttggat
    55141 catttcctta ccaagataat ggtcgatacg gaaaatttgt tcttcgtcaa atgttgctag
    55201 gagttcgtca ttcaacttgt ttgcagttgc gtaatctgta ccaaatggtt tttcaacgat
    55261 caagcgctca aaacctttgc catcgacaat gttttcagat ttgaggtgtt tggcaatggt
    55321 tccaaagaac tgaggtgcca tagacaagaa gaagagctta ttgtgttcag cttggtattt
    55381 ttcattaagc tcagcttgta attgacgcaa agcaatataa tgttccgaat cattgacatc
    55441 atggctttga tagtagaagt ggctagcaaa ttcttgggct tgctcggtac tatctgccaa
    55501 atcaaggatg gactcgacaa ctacagattc aaaatattcc ttactccaag gtctacgggc
    55561 agttccaata acggcaaagt gcttggaaag attgccggat ttatatagtc taaaaaggga
    55621 agggtagagc ttgcgtttag ccaggtctcc actcgcaccg aaaattgtaa caataacctt
    55681 agatgacatc tagctaccta atttctattt ttattcctag tcttgctagg tatgaggaaa
    55741 cctcatttca taaacttaat tctaacataa ttttccgaaa aatcaaaaat tccaatacga
    55801 ggtagaaaaa ctgcaaggaa atccttacag tttgagttta gacgtttaag accttatcta
    55861 agaactcttt cagacgaggg tgttgtgggt tatcaaagat ttggtcaggt gttccgtctt
    55921 caaggaactc gccatctgca gtaaagataa cgcggttggc aacctgacga gcaaatccca
    55981 tctcatgggt tacgataatc atggtcatgc cttgctcagc caattccttc ataacgttaa
    56041 gtacgtctcc aaccatctca gggtcaaggg cagaagttgg ttcatcgaag agcatgatgt
    56101 ctggattcat tgctaggcca cgagcgatgg ccacacgttg tttttgacca cctgataggc
    56161 tatctggatt ggcattagct ttatctgcta gtccaacctt ttcaagcaac tccattccca
    56221 attcctcagc ttcttcctta gtcatcaact tgtgctcaat aggagcaaag gtgatgttgt
    56281 ccaatacaga catatgaggg aagaggttga agtgttggaa taccatgccg atattttcac
    56341 ggacgtggtc aacattggtt gttttttcag ttaaatcata gccgttcaca gtgatgtgac
    56401 cgctagtgac ttcttctaaa agattgaggc tacggaggaa agttgactta ccagaacctg
    56461 aaggaccgat gatacaaaca acatctcctt catagaactt agtcgtaatt ccttttagga
    56521 cttcattttt tccatagtgc ttgtgtaaat catttacatc aatttttaat tttgccatta
    56581 acgaatcctc ttttctaagc gtttcgctag tctagtcaaa agtgtgataa ttacaagata
    56641 gaagatagca aggattgcat acatcttgaa actttggtag ttacgagcaa tgataatctt
    56701 accagtttgg aagagttcaa ccaaaccgat agcagatacg atagttgtat ctttaagagc
    56761 gataacgaat tggttgacaa agtttggcaa catcaattta gttgcttgtg gcaagataat
    56821 cttacgcatg gtttttccat aagagatacc caagcttcgg ctggcttcca tttggccaac
    56881 tggaacggcc tgaataccac cacgaacgat ttcagcgata taagcagccg cattgagtga
    56941 gagggcaatg gttccagcta caaagtcgtt aattgggctt tgttggcctg tgatagactc
    57001 gatgaagttt ggaattcccc agaagatgaa ggctgcaaga atcatcaatg gaataccacg
    57061 aataacgtca acgaaaatct cagagatgac gcgaagagat ttgtatgggc taacgctaaa
    57121 cataccgaag ataattccga tgacaatggc aatagcaaat gagataagag ctagagcaag
    57181 agtgatacca agaccgctaa ggagttgttt gtagttgttt tgaagcaagc cccagagcgt
    57241 tgtttcgtca acagtacttg ttgaagcagt tgaagattcg ctagctaggt atttgtcaag
    57301 aatcttttgg aattcaccgt ttgccttaag gtttgcaagt ccgttgttga acatttcaat
    57361 cagttctgga tttgctcctt ttttaacggc aaaggctgtt tcaccgattg gagttccaga
    57421 gattggagtt ttcaattttt gaccttggct gatagaatat ttgagaacag gttcatcatc
    57481 cataacggca tcaatggcac cagtgtttaa actgtcatac attgaagaac catcagcaaa
    57541 ggttttgatt ttgtaaccgt atttgctttg attttctgtt aggaaggttt gagaagcagt
    57601 tccgttttta acaccgactg tctttccttt tagatcttca taagaagcaa tattgcttga
    57661 ttctttgaca ccaagaatgg tattagcagt gtagtatgat tctgagaagt caaaagttgc
    57721 cttacgagca tctgtgacag acataccagc aatgatacca tcggcttgac cagcttggac
    57781 agcactgata gcagcatcaa aaccagggtt ggtgatttca atttcaaaac cttggtcttt
    57841 agcgattgcc ttaatcaatt ccatatcaat accagtgtat tggttgcttg aattttggaa
    57901 aacaaaaggt gcaaaagaag aatcgctggc aatgatatat ttagccttaa caggaatagc
    57961 ttttaatcct gcgagagtag ttgtagttgg cactgctgaa gatgatgaag cagtccattt
    58021 cttgataatt ttatcaagac taccatcttt tttcatttca gccaaggctt ggttaaattc
    58081 agtaaccagg tgctcgtatt tacttccttt tttcacaccg aaagcaaaac ttcctacagc
    58141 ttcaccatcc atttcaatat ggaggtcttg accttggtta atggcatatt cgataacagg
    58201 tttgtcatcc atcatggcat cgatggcacc agcactcaag ctgttgttca ttaaatcacc
    58261 agtgtcaaat gttttaatag taaagccgta tttatctttg attgtttcaa ggaaacgttg
    58321 agcggcagtt ccgtttttaa caccaacggt tttgccagtt aattggtcgt acttgctaat
    58381 tttgtgtgac tttgtagtag caatgacaac ttttgtatca tagtaagtat cagacatggt
    58441 gaagactttt tcacgttctt tagtctttgt catccctgcc atgatagcgt cggcttgccc
    58501 agcttgaacc gcattgaccg ctgcgtcaaa tccaggatag gacatctgaa tgttccagcc
    58561 tttaatctca gcgactttgt taataatgtc aacatcaatt cctttataag tttgatctga
    58621 atctttaaac tcaaaaggtg cataggcggt atcagaaaca atcttaatcg tttctgcttt
    58681 ggcaatacct aatgagaaaa ttgggaataa aattagcaaa aatgctagaa attttttctt
    58741 catttttagt ctccttttcc gaatattctc tcattatatc agaaaaagta aaaaaaggca
    58801 aatttttata ttttccgtgt cagaaaatat aacattgatt tttccttttc tttcttgaat
    58861 tgctattaaa aagtgctata ataatagtat atatagaaga aaagaggacg gggatatgaa
    58921 gaataaaaga atatttaaag acttccaagc ttcaaaaatg aatttaaaca tttacacaag
    58981 ccccttgtta gcctttgttt ttgttttcat aggagagttt gtggcttata ctttatatgg
    59041 tattagtttg ttagctctca tcggacttgc tagaaatttt ggagaggctg gtcaaaatct
    59101 tgcaagctac ttgcagacct tgcatcagag cttgacggat aaaacaagtg actttcgttt
    59161 aattttagga ttactggcct ttggttttat tcttaacact gtgttcagat ggacaagaaa
    59221 agttgagaaa agacctattc gaaccttggg attttataga gagaatttcc tcagcaatct
    59281 tctgaaagga tttagtctag gcctggcact ttttcttctg accttgttag gtttagtggt
    59341 cttaggtcaa tatcgtttgg aatccattca cttgaatcct tattctcttg cctttgtcgt
    59401 ctttactatc ccattttgga ttttacaggg gacagcagaa gaagtggtgg cccgtgcttg
    59461 gctacttcct caattggcct caagaaccaa tctaaaacta gctattctta tatctagcct
    59521 gttctttacc ctgcttcata tgggcaattc tggcctcacc cctctatctc tagtaaatct
    59581 ctttttattc ggagttgcca tggctcttta ccttctcaaa actgatacag tttggggtgt
    59641 tgcaggtatt catggtgctt ggaattttgc tcagggtaat ctctttggga ttttagttag
    59701 tggtcaaccg tcaggaacgt ctctgatgac ctttttacca caaggcaatc aagattggct
    59761 atcaggtggt tcttttggca tagaaggttc cattatgaca agtctggtat tactactgct
    59821 gattgtctat cttgctaata aattaaagaa agaaaatgaa aggatgtgac ttcggtccgt
    59881 ccttttcttc gtgaaaatac tataagtatg ctaaaatagg aatagcacat ggagagagga
    59941 ttcttatgat caatcacatt acagataatc aatttaaact agtatcaaaa tatcaaccat
    60001 caggagatca accccaagct atcgagcagt tggtggataa cattgagggg ggagaaaaag
    60061 ctcagattct gatgggggcg actggaacag ggaagaccta tactatgagt caggtcattt
    60121 ctaaagtcaa taaaccaact ctggttattg cccacaataa aactctggct ggtcagctct
    60181 atggggagtt taaggaattt ttccctgaaa atgcagttga gtatttcgta tcctactatg
    60241 attattacca gccagaggcc tatgtccctt ctagcgatac ctatattgag aaggatagtt
    60301 ctgtcaatga cgagattgac aagcttcgcc actcagctac ctcagccctt ttggagcgta
    60361 atgatgttat tgtcgtggcc tcagtctctt gtatctatgg tttgggttcg cccaaggaat
    60421 acgctgatag tgtcgttagt ctccgtcctg gtctagagat ttctcgtgat aaactcttga
    60481 atgacttggt cgatattcag tttgaacgca atgatattga tttccaacgc ggaagatttc
    60541 gcgttcgtgg ggatgtggta gagattttcc cagcttcccg agatgaacat gcctttcgag
    60601 tagaattttt tggagacgaa attgaccgta ttcgtgaagt tgaggctctg acaggtcagg
    60661 tgttgggaga agtggatcat ttagcgattt tcccagcgac acactttgtg accaatgacg
    60721 accacatgga agttgccatt gcaaagattc aggccgagtt ggaagaacaa ttagctgtct
    60781 ttgaaaagga aggtaaactg cttgaagccc agcgtttgaa acagcggaca gagtatgata
    60841 tcgaaatgtt gcgtgagatg ggctatacca atggggttga aaattattct cgccacatgg
    60901 atggacggag cgaaggagag cctccttata cgcttctcga cttcttccca gatgatttct
    60961 tgattatgat tgacgagagt catatgacca tagggcaaat caagggcatg tacaatggag
    61021 accgttcgcg taaagaaatg ctggttaatt atggtttccg tttgccgtct gctttggaca
    61081 atcgtcctct acgtcgggag gagtttgaga gtcacgttca tcagattgtt tacgtttcag
    61141 cgacacctgg tgactatgaa aatgaacaga ccgagacagt gattgagcaa atcattcgtc
    61201 caacgggact cttggatcca gaggtggaag tccgtccgac tatgggacag attgatgacc
    61261 tcttgggtga aatcaatgcc cgcgttgaaa aaaatgagcg tacctttatc acaactttga
    61321 ccaagaaaat ggcagaggac ttgaccgact acttcaagga aatgggtatc aaggtcaagt
    61381 acatgcactc ggatatcaag accttggaac ggacggagat tatccgtgac ctgcgcttgg
    61441 gtgtctttga tgtcttggtc ggaattaacc tgctccgtga aggaattgac gttcctgaag
    61501 tgagcctcgt agctattctc gatgctgaca aggaaggttt ccttcgcaac gaacgtggac
    61561 tcatccagac tattggacgt gctgctcgta acagtgaagg ccatgtcatc atgtatgcag
    61621 acacggttac ccagtctatg caacgtgcta tcgatgaaac tgcccgccgt cggaaaattc
    61681 agatggccta taatgaagag catggtatcg taccacagac aatcaagaaa gaaatccgtg
    61741 acctgattgc cgtgaccaag gcagttgcta aggaagagga caaggaagtc gacatcaata
    61801 gcctcaacaa acaagagcgc aaagaactcg tcaagaaact agaaaaacaa atgcaagaag
    61861 ccgtcgaagt gcttgacttt gaactggcgg ctcagatccg tgatatgatg ttggaagtca
    61921 aggccttgga ttaggggaat agtatgattt atttaagaaa gttaaagaga gaagatttga
    61981 tgtctttatg ggaaatggct tattcacaac ttaatccagt ttggaaacag tatgatgctc
    62041 cctattatga tgattatcag tatttttcaa attttaaaga attcgaacta caaaaatcag
    62101 aatccatttt aagcaactca aatcgccttg gtatttttgt tgatgataaa ctagttggga
    62161 ctgtttcgcg ttattgggta tgtaaacaaa caagatggat ggaattggga attggtattt
    62221 atgataaaaa attctggaac actggtattg ggaaagttgc tatgttgcag tggatagata
    62281 ggacgtttca ggattacttg gagttggagc atctgggttt gacaacttgg tcaggaaatc
    62341 ttggtatgat gaaacttgct gaaaaattaa gaatgaaaaa agaagctcat attccaaaag
    62401 ttcgttatta tcaaggtaaa tattttgata gtattaaata tggtattttg agagaagact
    62461 gggagaaaat gaatgacggt tattatcaaa tcaatggaaa ctcctgaaga gatagaaggt
    62521 aaatcccttg ttcactggca aacgtggaga gaggcttatg atgacctttt gcctgcagaa
    62581 tttcaggaga caatgacatt agaaagatgt cgattcttta gtcaaaagta tccagaaaat
    62641 acattgattg cgataggtga tctgaaggta gttggtttta tcagttatgg taactttcgt
    62701 gatgagacta ttcaagctgg tgaaattatt gctttatatg ttttaaaaga ctattacgga
    62761 aaaggcatag cacaaaagtt aatgaaagca gctttgactg ctctgaatca tttttctgaa
    62821 attttcttat gggtattgaa agataacaag cgagccattg ctttctatca aaaaatgggt
    62881 tttacttttg atggacaaga aaagatactt gaacttggaa agcctataaa ggaaaaacga
    62941 atggtattct attctaaaat aattttaaaa agtagaagct aatggcactg gtaccaagtc
    63001 tgaaaattta ataaattaga aagcgagtaa atttatgtcc cgttcccaat taacgatttt
    63061 aacaaatatt tgtctgattg aagaccttga aactcagtgc gtggttatgc agtaccgtgc
    63121 tcctgaaacc aatcgctggt ctggttatgc ctttcctgga ggtcatgtag aaaatggtga
    63181 ggcttttgcg gagtctgtca ttcgtgaaat ctacgaagaa acaggattga ctatccaaaa
    63241 tccgcaactg gtaggtgtta aaaattggcc tttggataca ggggggcgct acattgtctt
    63301 ttgttacaag gcgaccgagt ttactggaac tcttcaatct tcagacgagg gagaagtttc
    63361 ttgggtgcaa aaagaccaga ttccaaactt gaatctggcc tatgatatgc taccattgat
    63421 ggaaatgatg gaagctcccg acaagtcaga gtttttctac cctcgccgta cagaagacga
    63481 ttgggaaaag aaaatcttct agtcttttac taaataacct agctgatcca aggcttcctc
    63541 gatatagtgg aggtcttgtt gtgtttcggc ttcgactagg tggtaatgga tgccatctgt
    63601 caattcagat agaggtctaa agtcagaatg ctcgacttgt tctagaaaat gttgcacatc
    63661 tctgcgacaa gacagtttaa gcaaggtttc aatttctcca taaacgggat ggtcaatcaa
    63721 ggtattctgg acatgcccac cattatcgac aatagcaagg agttcctgac cgatttcttc
    63781 aacttgatgt ttcactttga aaagtttgtg aacataagga ttggtatcaa tttgcttata
    63841 gatgtagcca cgattggtgg ataggatagg agcgccatcg gctctcaaaa ttgcaatgtc
    63901 ctgcacaatg acctgacgtg tgacatgaaa atgttccgcc aaactttggc cattaagggc
    63961 tttaggagct tctttcaaga gttggagcag ggcttgtttg cgatcttttg tcatagcttt
    64021 tccttttaac ggcgttttcg aagcacttta tagacagcta gtgctaatgt atagtctacc
    64081 atactatgga taattgtgcc aaatccaact agtacaaata gaacatagaa catgttttct
    64141 acattggtac ccgaagttgc gtaaaaaagg acacaggcta atacttcagc aagggcatga
    64201 acaacagcca aaacaaaatt gaaaacccag gaagattttg gtttatctag ggtatcgggg
    64261 aatttttgta ggtaaagagc tcctaaagca ccaaaagata tatgggaaaa agcccgaaaa
    64321 acgataacca tgggatagcc agccatcaaa aatccaaaac tagaggctag gatgacaaaa
    64381 actgccatca agggcgacaa gaacatggct ataaaaatag cgatgtggct ccccaaagta
    64441 taggaagcag gtggaatgac aatcttgaaa ggcataacaa ttggaatcaa aatcgcaata
    64501 gccgttaaaa gggctgtcat tgtcataaat tgtgtctttt tccgtgtatt cacaagaatc
    64561 tcctttttaa ctgcatatac actagtatgg tacaataaac cagacaataa agcaagaatt
    64621 tacttgggtt tatagatcat tttttagtta aaag
//
LOCUS       DAVHKZ010000006        64217 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000006 DAVHKZ010000000
VERSION     DAVHKZ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64217
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.006"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(91..1227)
                     /gene="lctO"
                     /locus_tag="VVO74_000518"
     CDS             complement(91..1227)
                     /gene="lctO"
                     /locus_tag="VVO74_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU5694595.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(1852..3342)
                     /gene="lysS"
                     /locus_tag="VVO74_000519"
     CDS             complement(1852..3342)
                     /gene="lysS"
                     /locus_tag="VVO74_000519"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU5694596.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKTIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(3470..3616)
                     /locus_tag="VVO74_000520"
     CDS             complement(3470..3616)
                     /locus_tag="VVO74_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEU5694597.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            3649..4566
                     /locus_tag="VVO74_000521"
     CDS             3649..4566
                     /locus_tag="VVO74_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275026.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEU5694598.1"
                     /translation="MYIAVWGSLGSFLLGLIVSIIRHYRIPVLAQVATAYIELSRNTP
                     LLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSAMQDSGIQVLFQGNNLLRILQGL
                     GVTIGISILSVLLSMMFGTVMGIIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFG
                     LARNFNINISGETSAIIVFTLWGTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYY
                     HIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFW
                     IYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            4567..5325
                     /locus_tag="VVO74_000522"
     CDS             4567..5325
                     /locus_tag="VVO74_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU5694599.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGASGCGK
                     STLLRCLNGLESIQGGDIFLDGQSIVENKKDFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKTQGRDKKEVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRTLLMHPE
                     IILFDEVTASLDSEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAHAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            5337..6209
                     /locus_tag="VVO74_000523"
     CDS             5337..6209
                     /locus_tag="VVO74_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5694600.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLARKTSSTRPMKKHFTQPTVTLLK
                     QMTWLLKVEKLISH"
     gene            complement(6289..6936)
                     /locus_tag="VVO74_000524"
     CDS             complement(6289..6936)
                     /locus_tag="VVO74_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694601.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(6933..7631)
                     /locus_tag="VVO74_000525"
     CDS             complement(6933..7631)
                     /locus_tag="VVO74_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694602.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLANWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(7641..8393)
                     /locus_tag="VVO74_000526"
     CDS             complement(7641..8393)
                     /locus_tag="VVO74_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694603.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(8393..9157)
                     /locus_tag="VVO74_000527"
     CDS             complement(8393..9157)
                     /locus_tag="VVO74_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694604.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMVVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(9253..9656)
                     /locus_tag="VVO74_000528"
                     /pseudo
     CDS             complement(9253..9656)
                     /locus_tag="VVO74_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9836..10468)
                     /locus_tag="VVO74_000529"
     CDS             complement(9836..10468)
                     /locus_tag="VVO74_000529"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU5694605.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(10502..11203)
                     /gene="pyrF"
                     /locus_tag="VVO74_000530"
     CDS             complement(10502..11203)
                     /gene="pyrF"
                     /locus_tag="VVO74_000530"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU5694606.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QLIKQATNPDFICLTPGIRPQGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            11524..11616
                     /locus_tag="VVO74_000531"
                     /pseudo
     CDS             11524..11616
                     /locus_tag="VVO74_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(11938..12651)
                     /locus_tag="VVO74_000532"
     CDS             complement(11938..12651)
                     /locus_tag="VVO74_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5694607.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFCKYLMETQG
                     KVNDQQELVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNETLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(12644..13483)
                     /locus_tag="VVO74_000533"
     CDS             complement(12644..13483)
                     /locus_tag="VVO74_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694608.1"
                     /translation="MSMIEVSHLSKSFGDKIALNNISFTVKEGQIFGFLGPSGSGKTT
                     TINILTGQFLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMSLYNNLLFYSK
                     FYNISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALINKPAVLFLDESTSG
                     LDPTTSRTIHELILELKTAGTTIFLTTHDMNEASLLCDYVALLNKGKLVEQGAPSELI
                     QRYNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLEDIFITLTGGK
                     LNA"
     gene            complement(13959..14834)
                     /locus_tag="VVO74_000534"
     CDS             complement(13959..14834)
                     /locus_tag="VVO74_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HEU5694609.1"
                     /translation="MDSRYSRTKGYYSLFYNEEYNKIQNKTVLVLGAGALGCYISLSL
                     SMYGVRKLIVADYDIIEPSNLNRQILYTESDVGKEKINVLSEKIHKYNSDVQVVPISI
                     KVSSLEELEKIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVSHKISYISGGFNGCYLII
                     DNIYIPTIGSCFGCRNINKDINKYTLSDKTKWPTTPEMPAILGGIMTNLIIKIFLGCY
                     NETLIDNAYVYNMRNHALSQEKYVLENGECPICKKNNKVKDNNIRAKTFIRSVCFCLL
                     SGGVAFYLLLGSSLL"
     gene            complement(15029..15826)
                     /locus_tag="VVO74_000535"
     CDS             complement(15029..15826)
                     /locus_tag="VVO74_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
                     /protein_id="HEU5694610.1"
                     /translation="MGLIDSMKSRKKINIFKISWDFNITLSEKLNYKRFNKNFEKILF
                     GIFPLALILQCFIMYIYRADILTNFQNFPITLNILLFWLLVVIISATIHEFSHAIIAN
                     NYQIEIPNCGIMLLLFNLAFFVDLSGVQFLKNKKQFLKIMLAGIASNSILSLTGLLVL
                     LFTSYKLLGLLFFIINLGMIFINSIPFFQYDSGIILRYLNSNNNNLNFQYIVQLLIAF
                     VIIYFPLSQLLQFLTPNIIVRSIGGVVVSILLSILYMIGRTKYVLRK"
     gene            complement(16617..17816)
                     /gene="divIB"
                     /locus_tag="VVO74_000536"
     CDS             complement(16617..17816)
                     /gene="divIB"
                     /locus_tag="VVO74_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU5694611.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEESES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     NQRSSRR"
     gene            complement(17826..18884)
                     /locus_tag="VVO74_000537"
     CDS             complement(17826..18884)
                     /locus_tag="VVO74_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU5694612.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(18888..20240)
                     /locus_tag="VVO74_000538"
     CDS             complement(18888..20240)
                     /locus_tag="VVO74_000538"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU5694613.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIATD
                     KNTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(20344..20985)
                     /locus_tag="VVO74_000539"
     CDS             complement(20344..20985)
                     /locus_tag="VVO74_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694614.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(20987..23008)
                     /locus_tag="VVO74_000540"
     CDS             complement(20987..23008)
                     /locus_tag="VVO74_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU5694615.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(23079..23378)
                     /locus_tag="VVO74_000541"
                     /pseudo
     CDS             complement(23079..23378)
                     /locus_tag="VVO74_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            complement(23742..23996)
                     /locus_tag="VVO74_000542"
     CDS             complement(23742..23996)
                     /locus_tag="VVO74_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU5694616.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(24016..25857)
                     /gene="typA"
                     /locus_tag="VVO74_000543"
     CDS             complement(24016..25857)
                     /gene="typA"
                     /locus_tag="VVO74_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU5694617.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            26019..26744
                     /locus_tag="VVO74_000544"
     CDS             26019..26744
                     /locus_tag="VVO74_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEU5694618.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            complement(26784..27011)
                     /locus_tag="VVO74_000545"
     CDS             complement(26784..27011)
                     /locus_tag="VVO74_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694619.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLEYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(27100..27480)
                     /locus_tag="VVO74_000546"
     CDS             complement(27100..27480)
                     /locus_tag="VVO74_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU5694620.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILRARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(27480..27749)
                     /locus_tag="VVO74_000547"
     CDS             complement(27480..27749)
                     /locus_tag="VVO74_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU5694621.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            27813..28721
                     /locus_tag="VVO74_000548"
     CDS             27813..28721
                     /locus_tag="VVO74_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU5694622.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLSHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(28775..29530)
                     /locus_tag="VVO74_000549"
     CDS             complement(28775..29530)
                     /locus_tag="VVO74_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU5694623.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(29551..30480)
                     /locus_tag="VVO74_000550"
     CDS             complement(29551..30480)
                     /locus_tag="VVO74_000550"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU5694624.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTVRPRKISKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTNASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(30495..31118)
                     /locus_tag="VVO74_000551"
     CDS             complement(30495..31118)
                     /locus_tag="VVO74_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU5694625.1"
                     /translation="MTDIKALALKYGGYTSLDKVYLVQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     DSDGLGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(31111..32349)
                     /gene="hflX"
                     /locus_tag="VVO74_000552"
     CDS             complement(31111..32349)
                     /gene="hflX"
                     /locus_tag="VVO74_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU5694626.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKFQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDS
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(32342..33226)
                     /gene="miaA"
                     /locus_tag="VVO74_000553"
     CDS             complement(32342..33226)
                     /gene="miaA"
                     /locus_tag="VVO74_000553"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU5694627.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVLHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHFVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            33347..33517
                     /locus_tag="VVO74_000554"
     CDS             33347..33517
                     /locus_tag="VVO74_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU5694628.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(33565..34404)
                     /locus_tag="VVO74_000555"
     CDS             complement(33565..34404)
                     /locus_tag="VVO74_000555"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU5694629.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRIDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(34501..35460)
                     /locus_tag="VVO74_000556"
     CDS             complement(34501..35460)
                     /locus_tag="VVO74_000556"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU5694630.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTVGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(35587..36585)
                     /locus_tag="VVO74_000557"
     CDS             complement(35587..36585)
                     /locus_tag="VVO74_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU5694631.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLTSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTV
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            complement(36635..37252)
                     /locus_tag="VVO74_000558"
     CDS             complement(36635..37252)
                     /locus_tag="VVO74_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU5694632.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(37253..38974)
                     /gene="pabB"
                     /locus_tag="VVO74_000559"
     CDS             complement(37253..38974)
                     /gene="pabB"
                     /locus_tag="VVO74_000559"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU5694633.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKNLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(39035..44746)
                     /locus_tag="VVO74_000560"
     CDS             complement(39035..44746)
                     /locus_tag="VVO74_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU5694634.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGTMGLVVLPSAGAVNPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPRKDEQAPVEPENQPEAPEEEKAVEETPKQEESTPDTKAEETVEPKEE
                     TVNQSIEQPKVETPAVEKQTEPTEEPKVEQAGEPVAPREDEQAPTAPVEPEKQPEVPE
                     EEKAVEETPKPEDKIKGIGTKEPVDKSELNNQIDKASSVSPTDYSTASYNALGPVLET
                     AKGVYASEPVKQPEVNSETNKLKTAIDALNVDKTELNNTIADAKTKVKEHYSDRSWQN
                     LQTEVTKAEKVAANTDAKQSEVNEAVEKLTATIEKLVELSEKPILTLTSTDKKILERE
                     AVAKYTLENQNKTKIKSITAELKKGEEVINTVVLTDDKVTTETISAAFKNLEYYKEYT
                     LSTTMIYDRGNGEETETLENQNIQLDLKKVELKNIKRTDLIKYENGKETNESLITTIP
                     DDKSNYYLKITSNNQKTTLLAVKNIEETTVNGTHVYKVTAIADNLVSRTADNKFEEEY
                     VHYIEKPKVHEDNVYYNFKELVEAIQNDPSKEYRLGQSMSARNVVPNGKSYITKEFTG
                     KLLSSEGKQFAITELEHPLFDKIKAGTVKNINFENIDINVSNQDNIATIANEINGTTR
                     IENIKATGTITARNNVAGFVNNIKENAALENVAFIGNINSVGNNSTVGGIAGSNYMGF
                     VNKAYVDANITAANASASMLVPLVTYMLNSYQYGTKSKVTNSVAKGTLDVKNTRFVGG
                     VVAKTWPWGVIKDIVTYAKVIKGEEVYGSNEINDGDARQFLSDIYRVNGASSGANNFT
                     NLQKIKQLTKEQADAKVATFNITADKLESELSPLAKLNEEKAYSSIQDYNAEYNQAYK
                     NLEKLIPFYNKDYIVYQGNKLNKEHPLNTKEVLSVTAMNNNEFITNLDEANKIIVHYA
                     DGTKDYFNLSSSSEGLSNVKEYTITDLGIKYTPNIVQKDNTTLVNDIKSILEPVDLQS
                     QTMYQHLNRLGDYRVNAIKDLYLEESFTAVKKNLTNLITKLVQNEEHQLNDSPAARQM
                     LRDKVEKNKAALLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGEKVSVLDRLIEIGS
                     KENNIKGSRTFDAFGEVLAKYTKSGNLDVFLNYNRQLFTNIDNMNDWFIDATKDHVYI
                     AERASEVEEIKNAKYRAYANLNVAQHRKMILPLLNITKSHMFIASNYNAIAIGSAEKL
                     GKKSLEDIKASVDYAADGYRNYYDFWYRLVPDNVKQYLLRDTVIPIWEGYNAPGGWVE
                     KYGRYNTDNVYTPLREFFGPIEKYYGYNGTGAYAALYDNPMDPRSDVSYVALNMIGDY
                     GISVYTHETTHINDRKIYLGGFGRREGTDAEAFAQGMLQLPVPGSGFNEYGSLGLNTV
                     FKKPNDGNQWYDTDPKSLTTRDDIDKYMRGYNDALMLVDHLEADAVINQNNKELNGAW
                     FKKIDKKFRDASQLNQWDEIRNLTTEEKDNLNITSIDSLIDQQLMTNRQIGNRVYKPE
                     VVSQYDQSPYVGVEMTAGIYGGNTSKGAPGAVSFKHNAFRLWGYYGYLNGFLGYTSNK
                     YKQQSTKDGESVLSDEYIIKKISNNTFNTIEEFKKAYFKEVKDKATKGLTTFEVNGSS
                     VSSYDDLLTLFKEAVKKDAETLKQEANGHKTVSMTNTVKLKEAVYKKLLQQTDSFKTS
                     IFR"
     gene            complement(44768..45331)
                     /locus_tag="VVO74_000561"
     CDS             complement(44768..45331)
                     /locus_tag="VVO74_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU5694635.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALTSRPKLIGGARAHYPQDAIRKF"
     gene            complement(45447..47138)
                     /locus_tag="VVO74_000562"
     CDS             complement(45447..47138)
                     /locus_tag="VVO74_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU5694636.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(47135..47872)
                     /locus_tag="VVO74_000563"
     CDS             complement(47135..47872)
                     /locus_tag="VVO74_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5694637.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            complement(48140..49252)
                     /gene="msrB"
                     /locus_tag="VVO74_000564"
     CDS             complement(48140..49252)
                     /gene="msrB"
                     /locus_tag="VVO74_000564"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU5694638.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            complement(49263..49829)
                     /locus_tag="VVO74_000565"
     CDS             complement(49263..49829)
                     /locus_tag="VVO74_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU5694639.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            complement(49849..50559)
                     /gene="ccdA2"
                     /locus_tag="VVO74_000566"
     CDS             complement(49849..50559)
                     /gene="ccdA2"
                     /locus_tag="VVO74_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU5694640.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGFLVLFGNASILSQLFE"
     gene            complement(50770..51630)
                     /locus_tag="VVO74_000567"
     CDS             complement(50770..51630)
                     /locus_tag="VVO74_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU5694641.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSINFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQFLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGVLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDQVFKKD"
     gene            complement(51809..53863)
                     /locus_tag="VVO74_000568"
     CDS             complement(51809..53863)
                     /locus_tag="VVO74_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU5694642.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLILPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            complement(53875..54129)
                     /locus_tag="VVO74_000569"
     CDS             complement(53875..54129)
                     /locus_tag="VVO74_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694643.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            complement(54122..54679)
                     /locus_tag="VVO74_000570"
     CDS             complement(54122..54679)
                     /locus_tag="VVO74_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU5694644.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            complement(54663..55619)
                     /locus_tag="VVO74_000571"
                     /pseudo
     CDS             complement(54663..55619)
                     /locus_tag="VVO74_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            55711..56070
                     /locus_tag="VVO74_000572"
     CDS             55711..56070
                     /locus_tag="VVO74_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU5694645.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKLSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            56282..57136
                     /locus_tag="VVO74_000573"
                     /pseudo
     CDS             56282..57136
                     /locus_tag="VVO74_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(57384..64070)
                     /locus_tag="VVO74_000574"
     CDS             complement(57384..64070)
                     /locus_tag="VVO74_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEU5694646.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVEEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTANVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEVTVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPSKLVLERYVGPGFEVPTYYSNYQAYESGHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGKERIFT
                     VINPDGSKEEKLREVVEVPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEADQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
BASE COUNT        19080 a        13804 c        11456 g        19877 t
ORIGIN      
        1 ttatttcatt ttactatagt tttcgatagc aatttattct tccaatacac gaagaaaaac
       61 ctccacattc agtggaggca atctgtttta tcaatacaat tttaagtcac gagggtcaac
      121 tgggaaggtt gggttgtatg gattgtgacg gagcttaaag tgtttgacat cttcaatggt
      181 ctgagctcca gacaattgca taactgtctt caattccgca ttcaagtgtt caaagacttg
      241 acgcacaccg acactaccac cgagagccaa gccataaata acagggcgac caatagctac
      301 caagtctgct cctgaagcca aggctttaaa gacgtgttga ccacgacgaa caccagagtc
      361 aaagacaatc ggcacacgtc tatcaactgc ttctgccact tcttgaagcg agtcaaaggc
      421 agctggtcca ccgtcgattt gacgaccacc gtggttggtt acccagatac cagaagctcc
      481 tgcagcaagt gaacgttcaa cgtcctcacg gcattgtggt cccttgacat acacaggaag
      541 accagagtat tcagcgataa attctacatc gcgtggagac aagcgttgtt tagctgattt
      601 gtaaacaaag tccattgatt taccagcacc ttctggcagg tattcttcaa caatcggcat
      661 gccaactggg aagacaaaac cattacgctt atccacttca cgattccccc ctacagtagc
      721 atctgccgtc aagacaatcg ctttataacc ttcagccttc acacggtcca tgatgtggcg
      781 gttgataccg tcatccttac taaagtaaaa ttggaaccaa tggggtgtcc cttgaagggc
      841 ttcagaaatc tctggaaggt caacagtaga gtaagagctg gttgtataaa gagaaccaaa
      901 ctcatgcaca ccacgcgcag tcgccacttc cccctgttca tttgccaatt tatgagccgc
      961 aacaggcgcc ataatgattg gtgaagatag tttttcacct gcaaattcaa tctctgtact
     1021 tggattttca acatcgcaaa gtgtatgagg aacgatgagt ttgtggttaa aggcgcggat
     1081 attctctctt aaagtgaaag tatcttccgc cccactagcg atatagccaa atgctgcttt
     1141 aggaataact tgttgcgcca ttggctccaa atcataggta ttgatgaagt ctacatgacc
     1201 ttctgcattg cttgttttgt atgacataaa atgccctcct tgattaagta agcgtttgct
     1261 ttttactaca caactataat aactcttttt tcaatcattt tcaagagttt tgcttaaaaa
     1321 ccatcttatt ttttcataca atatactagc cctactttcc ttaaactcta aactttagtc
     1381 tatattaagt gaatcgttga gattttttgc tgccaggcat ttgaactact tttttatttg
     1441 cggattctat ctactaatac tataaaaaaa caagtgaata agacaccaga acatcctcta
     1501 ataggaccta tggacttata tcagtcccat atatactgtt taagcaagat actatcctag
     1561 ttgacgctaa cttcctatcc cacttattaa ttttttattt atagtgaatc tgaacaaatc
     1621 aattggggaa tccaagtcaa tttctagtac tttttgaaca gtttcagcgt actatcgtaa
     1681 aatgaaataa aacatgcaca aattgcttag ggaatttaaa ccaatttcta acaatgtctt
     1741 agaaatcaaa gtgtactatt tcaacttcaa tatactacac ttcattttct ccttaaattc
     1801 agtctctttt tgaatcaaaa aatcccctgg taagagccag aggataagaa tttatttcat
     1861 tgttgggaag agcaatacat cacggatagt tgttgtatca gtgaggagca tgcagagacg
     1921 gtcgataccg attcccaaac cacctgttgg tggcataccg tattcaagag cttcaatgta
     1981 gtcatagtcg attcctgtcg cttcatcatc accaagttct ttggctttag cttgggcttc
     2041 aaaacggcta agttggtcga ttgggtcgtt caactcagta aaggcattac cgtactcctt
     2101 agtcatgata aagagctcga aacggtcagt aaagcgttgg tcttcaggat ttttcttagc
     2161 gagtggagat acagctactg gatgtccata gacaaaggtt ggttggatta aagtttcttc
     2221 aacaaactct tcaaagaagg cattgatgat gtgaccaacc tcagtgtagt gtttctcaac
     2281 tggaactttc ttctcagcag cgatagtttt agcttcttcc aaagtcatgt cttgccagaa
     2341 atcgacacca gtaatttctc tgatagcatc caccatatga acacgcttaa atggttcgtt
     2401 aatcttgatt tcagtacctt ggtagttgac tgggccatcg cctttgactg atttagcagc
     2461 atgttggata atgccttccg tcaagtccat gatatcttgg aagtctgcat aagcttggta
     2521 aacttcgata gaagtgaact cagggttatg agtagcgtcc attccttcgt tacggaagat
     2581 acggccaatt tcatagacac gttccatacc acccacaata aggcgtttta agtgaagctc
     2641 agtcgcgata cgaagcacca tgtcaatgtt ttgggcattg tggtgggtga taaatggacg
     2701 ggcagcagca ccaccggctt cattatgaag aacaggtgtt tccacttcaa ggaatccttt
     2761 ttggtcaagg taacgacgga tttcagagat gatttttgaa cgagtgacaa agcgttcaaa
     2821 gctttcacga ttagaaatca agtcaaggta acgtttacgg taaattgttt caacgtctgt
     2881 caaaccatgg aatttctcag gaagaggacg aagagcctta gacaagtgtg tgatgtgggt
     2941 tgccttgata gagagttctc ccatatccgt acgcatcact tcaccttcga caccaaggaa
     3001 gtcaccaagg tctgcttttt tgaagatttc gtagttttct tcaccgacag catccttacg
     3061 aacatagatc tgaatctggc cttcgcggtc ttgaaggtgt gcaaaaccaa cttttccttt
     3121 accacgtttg gttaccaagc gtcctgcgat agtagctgtt tcgtttttat cgtgtaattg
     3181 ttctttatcg aggttggcat atttatcttt taattcttgt gaatttgcag tacgttcaaa
     3241 acgttttccg aaaggatcga ttccttgttc gcggagcgca gccatttttt cacggcgaac
     3301 gatctgctgg tcatttagtt cttccatatg ttctgtagac atgggatcct cctagtttta
     3361 ctcaaaattg aatacgatga gtcatttttt gcgatactcc cattttatca taaataagca
     3421 agaaattcac ggataatctt taaaaactaa aaagaacctg acgctaaaat cactggaaag
     3481 aagtgaaagt atcttccgcc ccactagcga tatagccaaa tgctgcttta ggaataactt
     3541 gttgcgccat tggctccaaa tcataggtat tgatgaaatc tacatgacct tctgcattgc
     3601 ttgttttgta tgacataaaa tgcactcctt gataagtaag cgtttacttt gtatattgca
     3661 gtttggggaa gtttgggatc ctttctgctc ggtttaatcg ttagtatcat ccgacattat
     3721 cgaatccctg ttttggcgca agtagcgaca gcctacattg aattgtcacg taatacgccc
     3781 cttttgattc aactcttctt tctctacttc ggtcttcccc gaatcgggat tgtcctatct
     3841 tcagaagtct gtgcaacgct tgggcttgtc tttttaggag gctccgccat gcaggattcg
     3901 ggaatccaag tactctttca aggaaataat ctcctgagaa tcttacaggg attgggcgtt
     3961 acgattggga tatccatcct gtctgtcctc ttatccatga tgttcggaac agtcatggga
     4021 atcatcatga cctcccattc tagaatcata cgatttttaa cacgattgta tctggacttt
     4081 acccgtatca tgccccagct ggtgctactc ttcatcgttt actttggctt ggctcgaaac
     4141 tttaatatca atatctcagg tgagacttca gctattatcg tttttaccct ctggggaaca
     4201 gctgaaatgg gagacttggt acgtggagct atcacttctc tccctaaaca tcagtttgaa
     4261 agtggacaag cactcggctt gactaatgtt caactttact accacatcat catcccacaa
     4321 gtcttgagaa gactgctacc gcaggctatc aatcttgtca ctcggatgat taaaaccact
     4381 tcattagttg ttttgattgg ggttgtggaa gtgaccaaag ttggacaaca aatcatcgat
     4441 agcaatcgcc tgaccatccc aactgcttca ttttggattt atggaaccat tctagtctta
     4501 tatttcgcag tttgctaccc tatttccaaa ctatccactc acttagaaaa acattggaga
     4561 aactaaatgt ctgaaactat cttagaaatc aaggaactaa aaaaatcctt cggagacaat
     4621 cccatcctcc aaggactttc tctagaaatt aaaaaagggg aagttgttgt catcctaggg
     4681 gcatctggtt gtgggaaaag taccctcctt cgttgcctca acggcttaga aagtattcaa
     4741 ggtggagata tttttctgga tggtcagtct atcgttgaaa ataaaaaaga ttttcaccta
     4801 gttcgccaaa agattggcat ggtctttcaa agttatgaac tctttcccca tctggatgtc
     4861 ttacaaaacc tcatcctagg ccctatcaaa actcaaggaa gggacaagaa agaagtaacg
     4921 gaagaagctt tgcaattact agatcgtgtc ggtttgctgg ataaacaaca tagctttgcc
     4981 cgtcaattat ctggtggaca gaagcaacgt gttgcaattg tccgtaccct cctaatgcat
     5041 ccagaaatca tcctttttga cgaggtgact gcttcgctgg attcagaaat ggtgcgtgag
     5101 gtgctggaac ttatcaatga tttggcccaa gaaggccgta ccatgatttt agtaacccac
     5161 gaaatgcagt ttgcccaagc cattgctgac cggattatct tcctcgacca agggaaaatc
     5221 gctgaagaag gaacagctca tgccttcttt accaatccgc aaaccaaacg agcccaggaa
     5281 tttttaaacg tctttgactt tagccaattt ggctcatatc tataaaggag attcttatga
     5341 aactattcaa accactctta actgttttag cacttgcctt tgcccttatc tttatcactg
     5401 cttgtagctc aggtggaaac gctggttcat cctctggaaa aacaactgcc aaagctcgca
     5461 ctatcgatga aatcaaaaaa agcggtgaac tgcgaatcgc cgtgtttgga gataaaaaac
     5521 cgtttggcta cgttgacaat gatggttctt accaaggcta cgatattgaa ctagggaacc
     5581 aactagctca agaccttggt gtcaaggtta aatacatttc agtcgatgct gccaaccgtg
     5641 cggaatactt gatttcaaac aaggtagata ttactcttgc taactttaca gtaactgacg
     5701 aacgtaagaa acaagttgat tttgcccttc catatatgaa agtttctctg ggtgtcgtat
     5761 cacctaagac tggtctcatt acagacgtca aacaacttga aggtaaaacc ttaattgtca
     5821 caaaaggaac gactgctgag acttattttg aaaagaatca tccagaaatc aaactccaaa
     5881 aatacgacca atacagtgac tcttaccaag ctcttcttga cggacgtgga gatgcctttt
     5941 caactgacaa tacggaagtt ctagcttggg cgcttgaaaa taaaggattt gaagtaggaa
     6001 ttacttccct cggtgatccc gataccattg cggcagcagt tcaaaaaggc aaccaagaat
     6061 tgctagactt catcaataaa gatattgaaa aattagcaag gaaaacttct tccacaaggc
     6121 ctatgaaaaa acacttcacc caacccacgg tgacactgct aaagcagatg acctggttgt
     6181 tgaaggtgga aaagttgatt agtcattaac tcttaaaagg aactggattt taagctccaa
     6241 tcccttttta agattttacc tataacatcc tgagtctatc taagatgttc aatctgaaca
     6301 cagtgtacat actttatctt ctattgcata tactttatca cataagatac gaatatcctc
     6361 ttcactatga ctagcaatca aaattgttgt ccctttttca ctagagagct ttctaaacaa
     6421 tgttctcata ttttctacac ttgatttatc caaggcattc ataggttcat ctagtaaaag
     6481 aatagaggga ttctccataa ttgcttgagc aatccctagc tttttcctca tacctagcga
     6541 ataagtttta actttctggt ctttttgctc atatagacca actattttca gtgtatcatt
     6601 gatttcctga ttaccaacta ctcctcgtat gcttgccaaa tattgtaaat tcttaaagcc
     6661 actataataa tttataaaac caggttcttc aatcaaagct cccaaattag ctggaatttt
     6721 tctctcagga acaatatttt ccccattgat taacacttct ccataagacg gactatataa
     6781 accagctatt aatttaaaca atacactttt acctgagcca ttcgcaccag taattcctat
     6841 aatttccccc tgtttacaac taaaattaag gttttgaaaa acacatgttt tttttaattt
     6901 caactcaata ttttttaatg taattatttc attcattcta taaacctcct cttttgacga
     6961 gtgaaataga aaatgctttt aaaaagaaag actaaaaata gcaactgaag aaataaatct
     7021 cgtcctatat ctccattccc tcgattcaaa atataaaata gataattagt tcgatttcct
     7081 acaaatagac caccaaacac aatcatgagt aaaaagaaac taacgcaagc aaagttcatt
     7141 tgtacattcg ctcctagtgc gtataacata aagcaaagca aggatagcac acaagcattc
     7201 aaagaatcaa ctataaacaa aactcctata tcccagtttg ctaactgtaa cataaattga
     7261 atcactagaa cttttaccat gattaaaatg agtccataaa gaaaacaggt ccaaatctga
     7321 tacctaatcc agagcttaat agaagaaaat cgaatcactt ccataaagaa atcggatgct
     7381 cttctacgat atacaactgc tagaaaaaat gtatgaataa taaaccaatg aagcaaccat
     7441 atagataaga ctaaaaaaga gttttgactc agattaggcc cttttaaaat ttctataaca
     7501 agtctatcat ttccttctaa ccaataccat aatcctaaac aaatcaatat ccaaaaaaga
     7561 acataacccc aaaagtactt ggtatagatt atctgattca acctccacat gtgactactt
     7621 aactttccca tttccaactt ttacactctc ctccagtttc tatgaacaga aaatacagtc
     7681 aatggaatta tgatagatag taatgtaagc caataaatca atgcatacgg attggaattt
     7741 accatatact gaaaaattgg caataatcca attatcccat tgttcaactg ataaatccag
     7801 aataaggatt ctacaaataa aaaagtaaac agaaatacta agctcatgtt tgatttttta
     7861 aaccaagaaa aactgctaat agtaagtaag gataaaaaga aatagtatgc tatataagag
     7921 aaaaaaaatc ctataaagaa actagcattg tttgcaatac ttataccata aaattctctt
     7981 aaaaaatcaa cctcctttat ctccaaagag aagctaaaac cattactaaa tgcaattaga
     8041 aaaatcaata aaaataaagt cgccgtccaa atccccgtac taagagctgc taatttgaaa
     8101 ctaaaactgg taaagtgctt aattgatttc agacgaatgc gacactccaa cctattaaaa
     8161 tagttattca tcaaataaaa aaagaacaat atatatgtga acggaaagca atatactcca
     8221 gtcgtcatat cttgaagtaa aactaaaatc cattctaata catttggatg gattgaatat
     8281 tggcgacagc gcaataaata tactgtacta gataaaacac aggatagcag taatataaaa
     8341 taaaccaata ctgctaagaa atctttttta taaaattgaa caaattgttt cattatacat
     8401 agtcctctga atgtagaaaa aatgtaccat aaacaaccaa acaactaaca aataaaataa
     8461 aagcaagatg cccactaact aaggaaagac tgatatcttt ctgatatccc aaagctagcg
     8521 ttgtcacagg ttctaagtaa gatagcccta aaatagccca taaaatacca ccaaccacca
     8581 tataggcaac tgggatgaaa atagctccta attttttctt cactagcaaa gcactagcta
     8641 gtccaaaaat agagaacaca gcgccccaaa ctccatacca gagagtcgtc acaagactat
     8701 agagaaactg attagaatca aataattctt ttaaggcacc actataatct ccaatataaa
     8761 tttcctgata aggagtcact aaaagattaa ttcctaataa taataaatag gggagaaaaa
     8821 agactagaaa agaagaaata attgcagtac tacctacaat agctagatac ctctttttag
     8881 aaattcggca caattgtgct gttagaaaat gactctcagc atcctctatt atctgactag
     8941 aatagggcag tgtacagata agtgcagcta ctaggctaat cggtgaaaat cctcgaatag
     9001 aagaagcggc aaaaaaaatc gataaacctt caattttata aataccattg aaagcaagga
     9061 aatttcctaa actcatgcaa agaagggtca aaaataaaga catataaaac cgaggtgatt
     9121 gaacgactcg tacaagatta caaatgaaaa attccatcct tactcctcct tataataaaa
     9181 atagggtgta gcattctttt ttcatgctac acccacaatc aaccatcttt aaggcttact
     9241 ctgacaagta agttaataag aatctggact ccaagaacct gaagtatgaa ttcttacatg
     9301 atttccaaat tgtggcgcca tagctaatct agtaccagaa ccaatataat tgtcaccacc
     9361 tccattatag tacatgacaa tcctagagcc agaccccaat gaatataccg gggtaatatc
     9421 tgacccacta taggcgctac gaatagaggt atttaacctt ttaccgccac cagtgctgtc
     9481 actattatta attccagcag aggcgttttc tttctcaagc tcactagttg tatccgaacc
     9541 ccaacgcggc aacgttaaat cataatttcc aatctgtcta gctaaaactg tagggagaaa
     9601 caaactagat gcaattgtaa ctacgcaaaa aaggaatata tttttcttct tttcatgaca
     9661 tcgtcctctt aagaagtgat aaacaagata gttgattgat caatttgata catattacat
     9721 tttcattata tcaataaaag aaagcgttgt caattatttt atttaaaata ttatcatatt
     9781 ttaaataaaa tggtaaaaga gactcggtag cctcgtctct ctttatctta ctgacctaac
     9841 cttcttgcca attttcttgg tcttctttaa agcgttttag aagatcaagg ccctctggcg
     9901 tgatgtaacc ttcttcttgg gctagatgga taagctcgct atagtttgaa agcgtcacaa
     9961 gtttaacacc agcatctgca aagttcttat ctgcttttgg caattggtag ctgaaaatcg
    10021 ctacaactcc aagtacatct gctccttctc gcttggctgc tgctacagct tcaagaactg
    10081 aaccacccgt tgaaataagg tcttcaacca ctaccatttt ttgaccttga gctacgcgac
    10141 cttcgatttg attaccagct ccgtggtctt ttggtttgct acggatgtag gcaaaaggca
    10201 agtccatctt atcagcaata atggctccgt gtggaatccc tgctgttgca gttcctgcaa
    10261 tcacttctac ttcaggaaag gcttctttga tagcttccac aaaaccattt tcaattaggg
    10321 tacgagtttc tggataggct agtgtcacac gattatcagt gtaaatcggt gacttgatac
    10381 cagacgccca agtgaagggt tcctctggtt tgaggtaaac ggcttggatt ttcaagaggt
    10441 ggctagcgat atctttagca agtgtcatgg tattctcctt ttatttttct aatctagttc
    10501 tttaattcca gtcctgtgtc cattcatcct tgatggcatg ataagctgca acaggatcct
    10561 cagcttgggt aatgggacgt cccactacga tatagtcact accaatttga taagcatctg
    10621 ctggcgtcat gacgcgtttt tggtctccaa cagcagctcc ctgtgggcga atccctggtg
    10681 tcagacagat aaaatctgga ttggtggcct gcttgataag ttgaacttcc tgtgccgagc
    10741 aaacgacacc atccaagcct gcttcagctg tcttcttggc atagtggatc acagactctt
    10801 gtaggcttgt ttggatattt tgaaactcct gcatctgggc ttctgatgtt gatgtcagct
    10861 gcgttacagc gatcaatttt gcttgacttc caagaccttc acgcgcagcc ttcatcatct
    10921 ctacaccacc agccgcatga acattggtca tatcgacacc aagctgagac aagaccttca
    10981 tggctgactt gactgtatta ggaatgtcat gaagtttgag atccaaaaag acactatgac
    11041 ccaaaccttt taagtaggac acaatctcag gccccgctgc gtaataaagc tccatcccta
    11101 ccttgagata aaggctttct tctgctggga aaagagctaa aaattccttg accgcctcaa
    11161 aactaggaaa atcaagagca atgattggac gatgttctcg cataggtttc tccttttacc
    11221 tttactagtg agagagtctg gccaacagaa gccacgaaaa aaggaacctg ccaacagcaa
    11281 ggttccacga aaaatgggta gtctccaccc tttcaccgtc taaccttagc tgcctctctg
    11341 gactgcttta aaggttttct attattctat tatttctact agcacttgtc aagtaaaaac
    11401 atggtcacgt atgtgttgac tgctattgaa cacctcacaa gactctttcc aaaagaatag
    11461 ttaaagactt tcactgagga cagagaaaaa gagtttgctt gttacccttt aattgaacaa
    11521 atgggaattc tgttttattt tgcggatgcc tattcatctt ggcaaagggg aagtaatgag
    11581 aatgcgaatg gacttcttcg tgagtatttt cttaaaccga tttggcaaca attaccgaaa
    11641 aaatccttaa tggtgctttg ctagcttatt aatcaccgtt cccaaaaata cttggattac
    11701 aagacaggtt ttgaagcact tatagaggag atttaaaaat gttgcatttt ttattgcaat
    11761 ttatcagtta tcttatcacc caaaacttct gcaattagta tgagcactat tgttattttt
    11821 cttttttcgt acactcaaat caaaatatag caataagact attctgtaga attgctgtca
    11881 aaaagatcag ttcatttttc cttcccactt gtgtttataa tcattaaaat aactcaatta
    11941 agaaattttc tttttcctaa tagttatcgt aattaaagtt aatagaagaa caatccaaat
    12001 aagtagtgtt agattaggaa ttagagtttc attccatgaa aatccctccc attttgtgaa
    12061 aaacttagta aacagtccca taaaactata atctgttatc ttcgcaactg tcttatccaa
    12121 accagatagc atcggtaaga aagcaactaa aatcatagca ggaagactga taacctgagc
    12181 tactacttgg ctcttcgcgg ttaaacctat caataaatag aataaaatga tggataaaga
    12241 ggttagaaga acgattgtaa tataattaaa agtatgtaca attgtaactc ctaaaataag
    12301 aggagtagtt cccataatca caaaagttag caaaaaagga agaaacatcg ttgataaaat
    12361 gtattcggat cctttaacac cactcaacag aagagtttgt aaattgtact tttctttttc
    12421 ttcagacaag ataatagtta taggacttcc aacagccaaa gccaaagaaa aaggtaaaca
    12481 catcatcaaa agaactaatt cctgttgatc gttgaccttc ccctgtgttt ccataagata
    12541 tttacaaaaa tatgtgaaag caaaaggcac taaaacttgc aataaaatac tcttattgga
    12601 aaggataatt tgacaacgca accataccaa agccagaaac cgtttaagca tttagctttc
    12661 ctcctgttaa tgtgataaaa atatcttcta aagtaggctc acatgaatga attgaaaaaa
    12721 tattttccag atcagcctga gatacctgtt ctagtgatgt aaaatcaaaa gttatctgat
    12781 tcccattata atctgtaacc ttaatctttt tatctttatt atatctttga atgagttcag
    12841 aaggagctcc ttgctcaact aatttccctt tatttaataa ggcaacataa tcacataaaa
    12901 gacttgcttc attcatatca tgagtcgtta gaaaaatcgt tgtccctgct gttttcaatt
    12961 ctaaaattaa ctcatgaatt gttcgagaag ttgtgggatc tagacctgag gtcgattcat
    13021 ccagaaagag tacagcgggt ttgttgataa gagctcgtgc taaaagcatt cgttgcctca
    13081 ttccagtgga taattttcct gctaccatct tgcgactatc atataatcct actcgcttta
    13141 acaaattatc aacacgtgat ttactaatat tataaaattt actataaaaa agaagattgt
    13201 tatacagaga cattttctca taaaatccac ttgtatcgct aaccaatcca attctcttta
    13261 attcaccgct tgttaaattt tgagattttt gtcccaaaat aatagattgt cctttatcgg
    13321 caaggaactg cccagtcaga atattaatcg ttgtggtttt tccagaacca gatggtccta
    13381 aaaatccaaa aatctgacct tctttaacag tgaagcttat attatttaaa gctattttat
    13441 caccaaaact ttttgataaa tggctaactt caatcatact cattgcacct cctttatatt
    13501 ctacattttt acttaacatc tatttactta gctttatcaa ataaacgtct taaaaaaaac
    13561 aataacatta agcatataac cgttagcaag attgtttcaa tattattgat aatatgatac
    13621 attctcaagc agtataaaat aattatatat atgcaaatgc tcattatacc tattttttta
    13681 aacatactaa gcctccttgc caaataataa agttatataa taactaagac acactatacc
    13741 taacataata aatatccaca gcattaaaaa tattatcata caaataaaaa tatccactgg
    13801 taactgaata aatgttctaa aattaacaag caaaaataaa atctcaaacg atgaaaaaag
    13861 ccatactata ttttccaatg atgtttgaat atttttattg tagtaagcat aatatatagc
    13921 aaaaataata cccaagaaca atactattaa ttgtgtttct ataacagtga actgcccaat
    13981 agcagataaa aagctactcc tcctgataat aagcaaaaac aaactgaacg aataaatgtt
    14041 ttcgctctaa tattgttatc tttcacttta ttattttttt tacaaattgg acattctccg
    14101 ttttccagaa catatttttc ttgacttaga gcatgatttc tcatattata aacgtaagcg
    14161 ttatctatta gggtttcatt ataacatccc agaaatattt taattattaa attagtcatt
    14221 atccctccca aaatagcagg catctctggt gtagtcggcc actttgtctt atcagataaa
    14281 gtgtacttat ttatatcttt gtttatattc cgacaaccaa agcaagaacc gatggtaggg
    14341 atatatatat tatcaataat aagatagcat ccattaaacc ctcctgatat gtaggatatc
    14401 ttatgcgata cagcaaattg attgacaatt tttataatat caatgggcgt atcaattgct
    14461 ttaacgataa aatctatact cccatattcc gcaacaattt tttctaattc ttctaatgaa
    14521 gaaactttaa tagaaatagg tactacctga acatctgaat tatacttgtg tattttttca
    14581 gaaagaacat taatcttctc cttaccaaca tccgactctg tataaagaat ttgcctattt
    14641 aaatttgatg gttctattat atcgtaatca gcgacaataa gtttcctcac tccatacata
    14701 cttagactta aagatatata acatcctaag gctcctgctc ctaatactaa tactgtttta
    14761 ttctgtattt tattatactc ttcattataa aataacgaat agtaaccttt agttctagaa
    14821 tatctactat caatatctat ctcatccgaa attaaaattt gttcatttaa tagttcaaat
    14881 gttagtttac tgcctaatac ttcttctatc tctaatagtt ccttgatcgt tgataaattc
    14941 ttgcgaaatt tgaggttcta tagctatttc ccgcatactc cgaccacgta aatacattat
    15001 accttctttt ttataagcaa aaacataact atttacgtag aacatatttc gtccttccta
    15061 tcatatataa tatagaaagc agtatagaaa caaccacccc tcctatacta cgaacaataa
    15121 tattgggtgt caaaaactgt aatagttgac tcaaagggaa ataaataata acaaatgcta
    15181 ttaaaagttg aactatatat tgaaaattca agttattatt gttagaattc aagtatctta
    15241 aaataatacc actatcatac tgaaaaaaag gaattgaatt aataaaaatc atacctaagt
    15301 taatgataaa aaataagagt ccaagcaatt tatacgatgt gaacaataaa acaagtaaac
    15361 ctgtaagtga taaaatcgaa tttgaagcaa ttcctgctaa cataattttc aaaaattgtt
    15421 ttttattttt taggaattgc accccactta aatctacaaa aaaagccaaa ttaaacaaaa
    15481 gtagcattat tccacaattt gggatctcaa tttgataatt attagcaatt attgcatgac
    15541 taaattcatg tatcgttgca gatataataa caacaagcaa ccaaaataaa agaatgttta
    15601 gcgttattgg aaagttttgg aaattagtca aaatatccgc cctataaata tacataataa
    15661 aacattgcaa aataagagcc aatgggaaaa taccaaatag gattttttca aaattcttat
    15721 taaatctttt atagtttaat ttttcagata atgttatatt aaagtcccaa gatattttaa
    15781 aaatatttat cttttttcgt gatttcatag aatctataag tcccatttta ctaagaacaa
    15841 tataaaatct taaataatat ttcttcccta ctaacactaa taagtccgat atggtaaatt
    15901 cttgacctat tagttgctct aaccattttt ttcctgtttc ccaactaata catgtttctt
    15961 actggatggt atatatagat gatactgtcc ctcataagga gtaggtaata tcttaatctt
    16021 atcaacaatt ctcataacaa acctaacctt taataaataa aagaggggct aagtaaaaca
    16081 tactctagtc cctcagtccg caatcaataa aataatgact aattctatta atctcttgct
    16141 gcaagactaa tacggaaaat tcaaatgact gtctaaaatg aaattgaaaa agcttgatgt
    16201 tagtaaatga acaaacttca acaaccagca agagcaagga ttgctaaacc aaatccgata
    16261 cctgttgcaa gtccagctga aaaatcacta actggtactg aaatttcttc aatttcctca
    16321 aataaaaagt tatcttgcat gattatcact ccctatcttt ttaacaacag gctactccaa
    16381 ttaagagaac taccccagtt ccaagtaaaa cttcccccaa aaattcacca tctgtagggg
    16441 ctacgatttc ttcaatttct tcaaataaga atacttcatc tgacatatgt gttaccttct
    16501 tcatcaaaaa ttattttgta atcgattaca ttgcagatgt aacataaaga aaaacaaatg
    16561 tcaaatatta aacgtaaaaa catggtcact aaagaactat aagagaaaag gtaaacctag
    16621 cgacgcgatg aacgctgatt tgtttgattt cgattgctct cttcctcttg ttttttctgt
    16681 tcttcttctt gttttttctc agcttccttg gcctcttgtt tggctttttc ctcagcctcc
    16741 ataattaatt tatccgccac agtgtaactg taaattccag cttccatgtc gaccacactc
    16801 ggttctgaca attgtggctt aatcttactg taatatggca gtttcttact catttcagat
    16861 agaggaacca agacttcgtc cgaatcattc atggtcaatc gaattaaatc ggatgtcacc
    16921 ttgcttgggg ctaattccac cttttggata gccgccttga gttctgggct aatttgagca
    16981 agttctgaga caaaaacctt gatttgttca ctatcattaa agagaactga taaataagtt
    17041 tctggtaaac tgttcagact cacagaacta gtctcaagct gaccactgga aagaatagga
    17101 taatgatttt caccagaaat atagtaggcc acaatatcat attccttgac cttaatagtg
    17161 aacttagttg gaaattgata gacaagttga gctgattcaa cccaatagtt agacttaatc
    17221 tgcttttcat attttgcctt gtctagcaga aggttaatcg tataatccga atcctgaatg
    17281 cctgaagcct gtcgaatatc atcagctgta gtttgcaccg ttccctcaac acgaatatct
    17341 ttcatggtcg cataaggact gagcaagtag gcagagacaa tcaataaaag cagacttgga
    17401 aataaaatcg tgaaggctcg caagatatgg ataccaggaa tctttgcttt ggctggtttt
    17461 tcctttgtag cctttttagc aagcttttta tcctgttcct ccttctcttt agactctgat
    17521 tcttctttct cttctttctc tttgtcagcc tctgaggatg ctactttttc ttcagactct
    17581 tccttagctg attctgaatc ttcctggtct gtttcactct cctggtcctg tttgtcctct
    17641 gacttctcag attcttctcc catccgagct tgtctttcct tttccttctc ctcagctaga
    17701 gccgcttcct cttcagcctt cttttttaga tattcttggt ttcgtttctg ccattctgat
    17761 aactctttca attcttcgag gatttctttg tcctcatttt tcttatcttt tgacatttac
    17821 tttccttatg ataaatcttt tttcaacaat tgataaaaat ctgctagaga tttcaattcc
    17881 ttagaagctt tcatcttagc ttggtaatct tccttgtgac ttagtaagtg agaaagcttc
    17941 tcttccaaac tatccaaggt caaatcgctt tcttgaaggt cttctgcata gcctttctta
    18001 acaaagtaag ctgcattttc aatctggtca ccacgactag cttcacgacc aagtggcaca
    18061 atgacatgca attttgctat cgccaagagc tcaaaaatcg tattggcacc accacgtgtc
    18121 acaacaatat cagccaattc catcaagggt tgatagagat cggtcacata gtcaacacga
    18181 aaaagatttt ggctcaactc attcaggcta gaatctccag ttagattgat aatattgtag
    18241 cgctctgtta gttctttctt atggtctgtc accaattggt taaagacacg agcacctgca
    18301 gaaccgccaa caaacaatac agtcggcaat ttatgattaa agtggctttg aatatccacc
    18361 aattcatctg gttctggatt tttttgatcc gaaaccttgg tcaccgctcc cacatgctcg
    18421 accttagcca aactcgaagc ttgttcaaag gttgaataca tcttagtcgc aaatttatag
    18481 gcgattttat tggccaagcc catagacagg tcagattcgt gaataaagac aggcactcct
    18541 gacacacgcg cagcgataac aggcggtact gagacaaagc ctccctttga aaaaagggtc
    18601 tgtggacgaa gtcgcaacat gataaagagc gattggacga ttccccagcc aactttgaag
    18661 acgtccagca tattttgcca agagaaatag cgacgcaatt tcccagtcgc aatagaatgg
    18721 aaggtgacat ccaaacctga cttaaggatt tcttggtgtt cgataccacg cttgtccccg
    18781 atatagtgga cttcccaacc atcttcgatg aacttgggca ttaacaaaag attgagggta
    18841 acgtgtccaa ccgtcccccc acctgtaaag acaatttttt tcatatttta ttcttttaac
    18901 tccgctactg tgtcgataaa gaggtcgcca cgtacttcaa agttagcata catatcccag
    18961 ctggcattgg caggactaag aagaaccaca tctccttgag tcgcaagttc ataggcctta
    19021 cgggtcgcat ctgcaatatc tgtcgcctcc acataagcga caccagcctt gtctgctgcc
    19081 cgtttgacac gttctgcaga ttgacccagg atgaccatct tcttgagtcc agtaatgtct
    19141 ggcaccaatt cgtcaaactc attgccacgg tccaaaccac ctgcaatcaa gacgaccttg
    19201 ctgttgtcaa atcctgataa ggctttttga gtagccaaga tattagttga tttactgtcg
    19261 ttatagaatt taacaccctt gatgtcatcc acaaactgga gacggtgttt gacaccaccg
    19321 aaggctgaaa gagtttcctt gatggtttga ttgtccacat cacgaagctt ggctacagca
    19381 atagtcgcaa gggcattttc cacattgtgg ctacctggaa caccgatttc attcgctgcc
    19441 atgactactt caccacggaa gtagagttga ccatcttcca gataagctcc atcaaccttt
    19501 tcaagtgttg aaaatggtac aacagtggct tctgtcttgg aagccaagtc ttttgccaag
    19561 tcttgattaa agttcaagac aaggaaatca gctgctgtca tcttgttctg gatattccac
    19621 ttggctgcta catattcctc aaataatcca tgataatcga tatgagttgg cataaggtta
    19681 gtaataaccg caatctcagg atggaattct tgaacaccca tgagttggaa agaagaaagt
    19741 tccataacaa gcgtgttctt gtctgtcgct atttgagcaa cctgactagc tggatagccg
    19801 atattccctg ataaaagacc atgttgccca gcagcagtca aaacttcccc aatcatagtc
    19861 gttgtggttg tcttaccgtt cgatcctgtg ataccaataa tcggtgcttc tgaaatcaaa
    19921 taagccaatt ccacctcagt caagactgga attcccttgg ccaaagcctt ttcaatcatg
    19981 ggattgttgt aggggatacc tggatttttc accataagag caaactcttc atccaagagt
    20041 tccaaaggat ggccacctgt aatgaccttg atcccttctt ccagcaaact ttgggcagct
    20101 ggattgtcct cgaaaggctt cccatcattt actgtcacaa tggcacctag cttgtccaac
    20161 aaacgagctg cagattcacc agacttggcc aaacctaaaa caaggacttt cttattttta
    20221 aattgatcta ttactttcat gtctcgaact ccatttctac tcctactatt ttaccatttt
    20281 tatggaaata aaaaagccac aaagtgtgtt tgtgactctt tcttctagct gaatcttgcc
    20341 atatcatcta tgtgataaat cggtaactcg aataacttgg tccacttgtt cccaaataag
    20401 aggattgtgg gtcgcaataa taatagttcg attcggattt tttaaagatt ctaggatgga
    20461 aagtaattcc tcagagtttt tggggtctaa ggaagcggtt ggttcatctg cgaggatcaa
    20521 aggtggatcc tttaaaatta tcttcgctaa tgcaacacgt tgtgcttctc ctcctgataa
    20581 ctcaaatata ggttgcttca aatccaaata agagaggttt acacggttta gagcttgttt
    20641 catcaaagag attttctctt tttccttcaa ctttttacca actaaaccca gattgagatt
    20701 ctctttgacg gtttggcttt caattaagcc aaaatcttga aataagtatc ctaagtaatc
    20761 tctaaagaaa acagaaggct tgatgtcctt aagagaagtg ccatcataga tgatttgccc
    20821 tttgtcatat ggctctaatc gtccaatcat attcaagagt gttgtcttac cacagccact
    20881 tgtaccgatt aaggcataaa ttttcccacc ttcaaaatga agattcgtat ctgaaaatag
    20941 ctgacggctt ccaaattttt tagatatatt ctttagttca atcatcctat tttcctttca
    21001 taattgtcat agaaacacga gattctttct gcgcttgacg gtaaagcgtc agaactgcac
    21061 tagctagaaa gactaataaa gtgagcaagc caatcaccaa gtctcgactg cttaaaataa
    21121 aaagactagc accaaataca aaactggcaa attgactaac catatactga gcatgtgttt
    21181 caaaaaatcg taaacctgaa attcgtttaa tcaagatatc tcggcggaat tgctcgaaat
    21241 atagaagatt gacagaataa aatagtaaca aggaactagc tatccccaca atagctccta
    21301 agattaaagt tgctgtttca gtttgaactt cattataacg agttagataa acacttcttc
    21361 cttctttaag ataggatact tgctcataaa ttccagcttt cttcaaaagt tctagcccac
    21421 tctcatatcc tttgataaag agttgttttc cagcattgat agaccaacta gatagggata
    21481 taaaactatc acctgtagaa gtcggcgtga ataccactaa aatcggatca gtcaaatact
    21541 gagtggatac gggattctca ccgttattat aaacaaaccg cttttctccc attgaaagat
    21601 aactaacgtg cgctttcatc tcataatcca aaggagcact tgcctcctca ccagattttc
    21661 cataataact caatctttct tcaaaaactt tcttaagttc tgcttctcga gagcgcaaat
    21721 gttctgggag caagaggata aactcacctt tttggagatg ggctaacttc tgtttggtct
    21781 cagcatctac cacgaccttt tccttgtcca aataactggg actaacatag agcgtattag
    21841 catctggact ataggtatcc agtgtctctc cctgttcatt ttttccttgt ggattggcaa
    21901 aatggagcag attatccttt acataaagag cttgttcttc ttcgattgct tccttggcaa
    21961 aggcatacca cttgctctga ttttctgtat cttttcctct atcacctaag ccaaaagaaa
    22021 tttgataata gtctgctcta tcctgccatg cttgttttga aatttcaagt tctttcaatc
    22081 gttggtaaga cgtcaaacct gtcttaacag cgtatcctac tgtaaagaca gcaaccaact
    22141 gacacaatag ggttaaaatc atcaggcgtt taaggggtaa tctcccctta ataacgggaa
    22201 ctaatgcttt gtaattcaaa ctcattagat aaagaagcat tagtaaaatt gaaatcgcca
    22261 ataaaaacaa cagatagaaa ctaatcccaa aaccataggt ggctaacaag ataggataaa
    22321 acaaaccttg actaaaaaga acgactcccc cacctaggaa ggaaaggagg gctgatagaa
    22381 ggagccattt gatatcagta gataaagaat gccccatgat ggataagaga gtctgaccag
    22441 aaaagagttt tatacctgct gctctcattt ccttaatccg agtgataatc actaaagcaa
    22501 agaaagataa gccaaatatt gctaaactaa ttaaaataag gggatttagt aatattcgaa
    22561 aagcaagaaa atagggcggt atctttcggt cagcacttgc tttataaccc aaatctccta
    22621 atttatcggc aagcttttct ttcgtcaagg agcctgacaa aaggagataa ctatttagcg
    22681 gatcactacg ttcacgactt tcttggctag cttcttggaa ttcttttggt aaagttccct
    22741 gaccataagt tgcataagta aagtgagtcg tcccatcctt actcggctct acaattcttc
    22801 tagctattaa actctgttct gagtttgcaa aattctccaa ttcctgttca aatacctcac
    22861 gcgtcggttc ctgagtatct tttttgacac gaagtaaaga aacggaatca tagcttgcat
    22921 ataaatattg tggcgcacgt aagacaataa tccaagcaag gaagaagctg agaaaaaaag
    22981 ttgataataa tatgaatagt ttcttcatag tagactcctt gtaaacaaaa ttccccctgt
    23041 aatttcttac aaggggaacg atttaaatca atgaacgatt agtcataatc acagtaaaat
    23101 gctacttgtt ctccccattt agtccaaatc catgcatagg aggtttttcc agcaggagct
    23161 tctcctttat cagaatgacc atcccatctg ctcacgatgg atgaataatg atatttttta
    23221 ccatgatagt aatttgaaaa agcctaacca cctcctgaac cttctccata tgtccatact
    23281 cctccatctg gatattgtac agcagctgat gcagctccca ataatgtaaa atttgaaata
    23341 agagctagag caagtaatct atgttttttc gttttcattt tattttttct ttcaaaaaaa
    23401 gcacaccttg agcaacaatg caacaaaata aatcctcctc tctcttttat tgaaaccgct
    23461 ttcttatgtg ataagaataa cttttttatt atttgttgtc aaggaaaaaa tcgaattttt
    23521 tagatatttt actatattac ctctgtgaat aatattatat agtagtttta tttcaaaata
    23581 atatgcaacc agtactaacc aaatataaaa tagatgccat taacgaattt tattcaagtt
    23641 tttcccattc atactataca agtaaaagag atggtgttaa ctaaaaagca attcaaacta
    23701 ttgtaaaatt cctagcaaaa agagagccga aactctcttt tttatcttct tttacttttt
    23761 ttgactggca tgagtgtgat gtctctaaca ctaaagtaag ctaggatcaa catggctatt
    23821 gctaggaata tttctgttgg taattgaaaa attttcagaa aagatagaac caataaaatc
    23881 aagagtgcca ctaaaataca taccatagcg acgatattga cagtcccttt aatgctttct
    23941 ggtgtcgcaa atacatagag taggagcagt aaaattccta ggactaaata gaccatcttt
    24001 ctctctttct agctcttatt cagctgattt tttcttcttg ttagctttct cacgctctgc
    24061 tttgttaagg atttgtttac gcaaacggat agactcaggc gttacttcca tgtactcatc
    24121 gtcgttcaag aactcaagag actcttcaag tgtcaagata cgaggcgtct tgataacagc
    24181 tgtttggtcc ttagtagctg aacgaacgtt ggtcatttgt tttgccttcg tgatgttaac
    24241 tgtcaagtca ttttcacgag agttttcacc gatgatcatt ccttcataaa cctcagtacc
    24301 tgggttgaca aagatcgtac cacgttcttc gatagacatg attgagtaag ttgtagcctt
    24361 accagcatcg atagaaacaa gggcaccacg gtgacgtcca ccaatttccc ctggaatcaa
    24421 tggcaagtat tggtcgaagg tatggttcat gataccgtaa ccacgagtca ttgataagaa
    24481 ctcagttgag tatccaatca aaccacgcgc tggaacaagg aagaccaaac gagtttgacc
    24541 attaccagtt gaaatcatat ccaacatttc acctttacgt tcagaaaggc tttggataac
    24601 agacccttgg tattcttctg gagtgtcgat ttgtacacgt tcaaatggtt cacatttaac
    24661 accgtcgatt tcttttacga taacttctgg acgagatact tgaagttcat agccctcacg
    24721 acgcattgtt tcgataagga ttgacaagtg caattctcca cgtcctgaaa cagtccattt
    24781 atctggtgaa tcagttgggt caacacgaag ggaaacgtct gtttgcaatt ctgcctgcaa
    24841 gcgttcttcc accttacgag aagttaccca tttaccttct ttaccagcaa atggtgagtt
    24901 gttgaccaag aaagtcattt gaagagttgg ctcatcgatg tgtaggattg gaagagcttc
    24961 tactgcatct gtcggagtga tggtttcacc gacaaagatg tcttccatac ctgaaacggc
    25021 aatcaagtca cccgctttgg cttcttggat ttcacgacgt tccaaaccaa agaaaccgaa
    25081 gagttttgta acacggaagt ttttagttgt accgtcaagt ttagaaaggg taacttggtc
    25141 cccaacctta actgtaccac ggaagacacg accgataccg atacgtccaa cgaagtcatt
    25201 gtagtccaaa agtgacactt ggaactgcaa aggctcatct gagttatcta ctggagctgg
    25261 gatatggtcg ataatcgtgt caaagattgg tgccatagtc gcttcttggt cagctggatc
    25321 atctgacaat gaagaagttc cgttgatcgc tgaagcataa accactggga aatcaagctg
    25381 gtcgtcatct gcaccaagct cgatgaaaag ttccaagact tcatccacta cttctgctgg
    25441 acgagctgat ggcttatcga ttttgttaac aaccacgatt gggacaaggt cttgttccaa
    25501 ggcttttttc aatacgaaac gagtttgtgg catggttcct tcataggcat ctacgaccaa
    25561 gacaacaccg tcaaccattt tcatgatacg ctcaacttct ccaccaaagt ccgcgtgtcc
    25621 tggtgtgtcc ataatgttga tacgagttcc gttgtaagca acggcagtat ttttagcaag
    25681 gatggtaatc ccacgctctt tttcgatatc gtttgagtcc atagcacgct ctgccaattc
    25741 agtacgtgca tcaagcgttt ctgattgttt caataattcg tcaaccaggg ttgttttacc
    25801 gtggtcaacg tgggcgataa tcgcaatgtt acggatatct tctcttaatt ttgtcatgat
    25861 ttcctctata atattcaaaa tttattttct aactgaacga ttataccata atttcaaata
    25921 aataacataa ctcaagcaag tgtaaatgtt ttcactccgc ttttcttttc acgtcaagcc
    25981 ttttcaaagc aagcgactta tgataagata ggcacagtat gcgtttagat aatttattag
    26041 cccaagaaaa agttagccga aaggccatga agcaagcact cctcagaggg gaaattctag
    26101 tcgatggttg cccagcccgc tccctagctc aaaatatcga tacaggacta caagaactcc
    26161 tttttcagga tcgaatcatt caaggctatg aacacaccta tcttatgctt cataaacctg
    26221 ctggtgtcgt tacagccaac aaagacaagg aacttccgac cgtcatggac ttgcttccat
    26281 ctgacatcca gtctgacaag ctctatgccg tcggccgact ggaccgagat acaacaggac
    26341 tccttctctt gaccgataac ggtcccttgg gcttccaact cctccatccc caatatcatg
    26401 tcgataagac ttatcaagtt gaggttaatg gacttctaac acctgaccat atccaagcct
    26461 ttcaaaaggg aattgtcttt ttagatggta ctgtctgtaa acccgcaaaa ctagagattc
    26521 tatctgcaag tccctccctc agtcaagcct ctatcaccat ttcagaagga aaatttcatc
    26581 aaatcaagaa aatgttcctc tcggttggtg ttaaggtgac tagcctcaaa agaatccaat
    26641 ttggggactt cacattgaac ccagatttag cagaaggtaa ctaccgccct ttgaaccaaa
    26701 aagagttaca aatcattaaa aactatttag agatgagtcg ataaaacaaa aaaagcttta
    26761 aaactaaagc ttttttcttt tatttaccga aaaattaagg cgattgctac aatccagtta
    26821 actacagaaa tcacaattcc taagatatta agaatctttt ctattttata ctctaattgt
    26881 gactcttttt ggtatgaaat agccaagacc aatcctatga tacccaaaat caggcctaca
    26941 attggaaata acaaaccaag aataatcgac aagataccca caaaaagtgg atttttcttc
    27001 ttttctttca tgttctaaga actctttaaa ttttatacaa attaattata ctataaaaca
    27061 atagcttcat cctatcattc gactaatttg gaaataaggt tagctagtct tcactttccc
    27121 tttccaagaa tccaagccat aagaaaggat ataaatctca gaaaaacctt gttttttcaa
    27181 gtaaagagct gcatttgtaa ctcgttgcgc acgttggttc tcgtagagaa ggacaggttt
    27241 atctttacga agggctgcaa gactagtttt caactgactt gaaggaatat tgcgtgcacg
    27301 aaggatatgt tttctgtgga attctgctgg gtcgcgcaaa tcaatcaatt gacccgtacg
    27361 aatcaaggct tcaaactcct cattgtccac aattttagcc gcacggcgaa tacgaagata
    27421 gttaaagccc atccacgcca acattgctag tataagtgcc cacaaaatcc aagtaaccat
    27481 tagttctttt ctccattttt ctcaatataa tccaattcta ccttgtgctc tctgcgaaga
    27541 actgcttctg cctctagata gtctaattta tccatcaacc ctgcatcgta aatccgagat
    27601 agttccaact tcatcagttc aatatcatat aagcgttttc ccatgtaaac aataatacca
    27661 aatcgtttga ggaattgctg cacatcatag aatgttttca taagactcat tctagcaaaa
    27721 ttttgtgttt ttttcaagaa gagactcaca caatgctcct tattttccta tcttctttgg
    27781 cgattctaag gcaagtgtgg tacaataaaa acatgagaat tcaacaatta cattatatta
    27841 tcaaaatcgt cgaaactggc tctatgaatg aggcagccaa gcaactcttt atcactcagc
    27901 ccagtctctc caatgcagtg cgagatttgg aaaatgaaat gggcattgaa atctttatcc
    27961 gcaatcccaa gggtattacc ttgacccgtg atgggatgga gtttctctct tatgcccgtc
    28021 aggttgtcga gcaaactcag cttctggagg aacgctataa aaatcctgtc gcccaccgcg
    28081 aactctttag cgtttcgtct caacactatg cctttgtggt caatgccttt gtctctttgc
    28141 tcaagaaaag cgatatggag aaatacgaac tcttccttcg tgaaactcgg acttgggaga
    28201 ttatcgacga cgtcaagaac ttccgcagtg aggtcggggt cctcttctta aacagttaca
    28261 accgtgatgt tttaaccaag atgctggatg acaatcacct gctatcccac catctcttca
    28321 cagcgcaacc gcatatcttt gtcagcaaga ccaaccctct ggcaaagaaa gacaaggtga
    28381 aactgtctga tttggagaat ttcccttacc tcagctatga ccaagggacg cacaactcct
    28441 tctacttttc agaagagatt ctttctcaag aacaccacaa gaaatccatt gtggtcagtg
    28501 accgtgccac cctctttaat ctcttgattg gtttggatgg ttataccatt gcgacaggga
    28561 ttttgaacag caacctaaac ggagacaata tcgtttctat cccactggat attgatgacc
    28621 cgattgagct ggtctatatc cagcatgaga aaaccagcct atctaagatg ggcgaacgct
    28681 ttatcgacta tctactagaa gaagttcagt ttgatagttg agaaatgata agaaccaata
    28741 tgtaggctag caacaacctg cacattggtt ctttttactt ataattaaaa gtttcccctg
    28801 ccaacttatc agctagcttg ggaaagagag tataaaactt atgggctagg ttcaacaaaa
    28861 tcgggagatt gagttctcgt ttattttttc ctataatctt gacaatcttt ttagccactg
    28921 catctgcctc taagaggaag cggtcaaccg atttaagata agttccatct gggtcagctt
    28981 ggtcaaaaaa tcctgttcgg attggacctg gattgactgt tgtcacatag actccatagg
    29041 gcataagttc gagtcgcaga gcatttgaaa aaccaatagc cgcaaacttg gtcgctgagt
    29101 aaagactaga cttgccagta gctattagac ctgccatgct gacgatgttg atgatatgcc
    29161 ctttgctgct ttccttcata cgagccgcaa ggtgacgaga cagattcatc agggcaaagg
    29221 tattgacctc aaacatctgg tgaatgtctt tatcagcaat ctggtcaaat ccctcaaaaa
    29281 tcccgtaacc agcgttgtta atcaagacat caatcttgcc atagcggaga taaagatcag
    29341 ttaccagagc ttctagggct gaatcgtcgg taatatcaat ttcaatcaat tctgcatggg
    29401 aataatttcc gtagagttgg gctaattttt ccttatttct accaagcaag atgagttggt
    29461 cattgggcag gagtttgacc atttcttgag ctagaccacc gctagctccg gtaatgagaa
    29521 tagtaggcat acttatcctt tctgtgactg ctagatttcc acttcttcca agtctttgac
    29581 cacatggaca ttttcaaaaa ttgtggcagc gtctttcttg agtttgctaa tatcttttga
    29641 gaggaaacgg gcactgatat ggttgagtag gaggcgtttg gcacctgctt ctaccgctac
    29701 ttgtgcagct tgcatattag ttgagtgacc atggttacga gcaatttttt catcaccctt
    29761 gccataagtg gactcatgaa ctaggacatc tgcattgaca gccagacgca cactagcatt
    29821 ggtttttcta gtgtctccta aaatagtgat aatcttacct ggacgtggcg ctgagatata
    29881 gtcagccgcc ttgatttcag ttccgtcttc caaaacaaga tcctggccgt ttttgatttt
    29941 accaaaaagc gggccgaacg gaacaccagc agccttgagt ttttcagcat ccagcgtccc
    30001 ttctagatcc ttttgcatga cacgatagcc aacacagaaa atagtatggt ccagctcctc
    30061 tgcatacaca gtgaatttat cggtctcaag gatttttcct agagaatctt ggtcaaactc
    30121 atggaaatga atgcggtagg gcagacgaga acctgacaca cgaaggctgg ttaagacaaa
    30181 tgacttgatt ccttgaggtc cgtagatttc caaatctgtc tgctcttcat tggcctgaaa
    30241 ggcacggcta gaaaggaaac ctggcaaacc aaaaatgtgg tctccatgca gatgggtaat
    30301 aaagattttg ctgatcttac gtggtcgaac tgtggtttcc agaatgcgat tttgcgtacc
    30361 ttctccacag tcaaagagcc aaacttcgtt aatctcatcc aaaagtttca gggcgagact
    30421 tgaaacgttg cgagctttag agggctgacc agcccccgtt cctaaaaatt gaatatccat
    30481 tcgatacttt ctaattaatc aatatataac atggctgtgc ggttttccga tcggaaatag
    30541 cgtttgccag aaaaagcagc agcttcttgc aataaatcct cttggctgta gcctttgaga
    30601 cgttttcgac catcagccaa tctttccaaa tcagtcaaag ctgtgagact ttctaggctg
    30661 acaacttcct cgtcctcgac aggcttcatg taaatcttac cagactcttc aaagactaat
    30721 tgatggggga aaatttgcgc aatttcaaag agcaagtcat ccgagatttt ctcctcattt
    30781 tcagagaaaa tccgaccaag gccgtcacta tcataacaaa aaccaaagga tttaccagac
    30841 agattaagcc gaataaaagg cttattttct agggtgaaac ttggctcagt attgtaaaga
    30901 ttcagttcct gactgagttc tgcaaaataa tccgtcgcag cctgaggact ctttttctga
    30961 tagagttctg caaagtaggc attaacaaca cttggcggag gtgtaataag tgttaactgc
    31021 tcctgctctg ttttaccagc tagaagctga accagataga ccttgtccag acttgtataa
    31081 cctccatact ttagagccaa agctttaata tcagtcataa aattcttcta acctccattt
    31141 atttttttcg gaaatgtagc ctgtaatcac ttcgctgtct tcctgataat cacgttcttc
    31201 cagaattgca acactctcta aatcatgaat cttgtaggac tttgaaaaag gcactcgcag
    31261 ggtaaatgct tcaaaaattt ccttaatctt atctagcaat aatgcttgca agttttcacg
    31321 actgtcctca gacttggcag aaatgagggt atatggcgtt tgggtaggcg tgaaatcctc
    31381 caccaaatcc gctttattat aaagcgtcaa gtgaggaata tcttccatgt ccaggtcttt
    31441 catgatggag agaaccgttt tttcatgctc ctcgtggtaa ggattgctag catcgataac
    31501 atgaaccaga aggtccacat gcttgctttc ttccaaggtt gacttgaaac tggacaccaa
    31561 ctctgtcggc aaatcttgga taaagccaac ggtatctgtc aaagttactt ggagattgcc
    31621 tcccagatga atactcttgg ttgtcgcatc cagagtcgca aagagctcat ctgcttcata
    31681 ctgggtctta ctggtcaaga tgttcatgat agttgatttc ccagcattgg tataaccaat
    31741 caaaccaatc ttaaaagtgc tagactccaa acgtttttct ctgacagtcg cacgattttt
    31801 ctcaaccacc ttgagctggc gctcgatatc cgtgatttga ttgcgaacgc tacgacggtt
    31861 cagctccagc tggctttcac caggaccacg ggaaccaatt ccccctgcct gacggctgag
    31921 cataatcccc tgaccaacca agcgaggcaa aaggtatttg agttgggcta ggtggacttg
    31981 gaacttccct tcatggcttc gagcccgcat ggcaaagata tccaaaatca actgcatacg
    32041 gtcaatgacc ttaacaccga gaacttcctc tagattgaca ttctgccttg gggtcagacg
    32101 gttgttgacg atgacagtag tgatttcttc tgcatccacc ataagcgcaa tctcttccaa
    32161 cttaccagag ccgacgaagg tcttggaatc atatttttca cgtttttgtc tgtagctatc
    32221 tacaacgact gcccctgccg ttttcgctaa actagccaat tcttccatgg agaggtcaaa
    32281 actgtccata ccctgcaatt ccacaccaat cagcaggact cgctcctctt ttttctccgt
    32341 ttcaatcatc taaaaactcc tctatctggc ttaaaatgcg gtcttgtaca ccagattctc
    32401 caatctgata aaaggtgacc tgcatgcgat tacggaacca ggtcagctga cgcttggcaa
    32461 aacgacgggt cgcctgttta agactctcac tagcttcctc aaaggtctgc tctccacgga
    32521 aataaggaaa gagttcctta tagccaattc ctttagcagc ctgtacatta ggggaatggt
    32581 caaacagcca cttggcctca tccaaaagcc cagcctcaaa catcaaatcc actcggtggt
    32641 tgatacgctc ataaagttga ctacgttcat catccaagca gataatcagc ggttcataca
    32701 aggtctcttg attttccaaa tcctgaccaa aatgggcaat ttctaaggca cgcatagcac
    32761 gacgacgatt aaactgggga atctcaaggc ctgcttgctc cacaaaatgg gctaattcct
    32821 catctgaata cggctccaaa ctagctcgat aagctaaaat ctcctcatga ggagtctccc
    32881 cacctaggtg gtaaccttct agcaagctct ggatataaag tccagtccca ccggcgataa
    32941 tggctagctt gccacggctg tgaatatcct caatagtcat cttagcttct gaaacaaaat
    33001 caaaagccga gtaagactcg gttatctctc taacatcgat taaatgatga agaacagctg
    33061 cctgctcttc tggactagcc ttagctgtcc caatatcaag tcctcgatag acttgttggc
    33121 tatctccact aaccacttcg ccattaaaac gctttgcaac ttcaatagct agagccgtct
    33181 ttccaacagc agtcggtcca acaatcacaa ttatttttgt tttcatcttt tttccttgaa
    33241 aaattcccat tttttcgtta ctattattat aacacaaaaa ggtcagtcag aaaaatgtga
    33301 cctcttgagg aggctggctg attgagaata taaaggagga agactcatgg ctaaaggatt
    33361 cgctaaaggt cttgtaacag gtgtcgcagg aactgtcgct gccgttgcag gtgcagtata
    33421 cgcatttaaa aagaaagtaa tcgaaccaga agagcaaaaa gcagctttca tcgaagaaaa
    33481 ccgtaaaaaa gcagctcgtc gccgagtatc acgttaagaa acaaaagaag ttgggattat
    33541 tctcaacttc ttttttctat tcttttaaat agctaggtca aacttcaact gtggcttaac
    33601 agggtcataa tccaccaact caaaatcttc tgctttgata tcaaagaaat tagtcccatc
    33661 aggaacattt aaaaccaagc gtggttggca gtttgacggc tcccgacgga gcaattcctg
    33721 agcttgttca aattgattat catagatatg gaggttgttg atgaagtaga agaacttccc
    33781 aaccttccag ccaaaatgtt tggcaatcat catctgcaaa gccacatact gcatagcgtt
    33841 gatgtggtgg gccaccagca tatcattcga gcgctgggtc aaggtcgcat ccagatagat
    33901 ttctccatct atacggcgga catcaaacat ggtctgaaag gcgcacggga gcagcccatc
    33961 tgtttcttcg aaagcttggt aatcccagag cgaaataata ttgcggcggt tccaaggatt
    34021 ggtttccaac tgtttgagaa gcttattgat aatgtcgtgt ttcttaacaa cggcaccata
    34081 gcgctcacca atggttcccg tgtctccaac ttcccagtca ttccagtagt gaacattgta
    34141 cttgtcatta agcacttcta agctatttga ctggtcttgg taaatccaga gaacttcttt
    34201 gatggcggat ttgattgcaa tgggacgcaa ggttgtgata ggaaattctc ctttagataa
    34261 gtcgtactcg gaaaaggcac cagttacata cttggaatta gcaacagtcc catccttgta
    34321 cttaggacga gcctgctctg agaaaacacc ttcctttaga atgcgttcaa tattctcttt
    34381 aaaaatcgta tctgcttttg tcatttcgtt tcacctcatt cattgtccta actagtatag
    34441 cataaaaaat aaaagaggaa cattactaac tctaggttag cattttcctc tctcattatc
    34501 ttattgcaat acaagtgatg ctgctccgat aactccagcg tcatttccta gagttgcaag
    34561 agctaattta gtagatgtgc gtacttgtgg gaaactattt tcatcgtaaa ctttttgaac
    34621 accttgtaga aggaattctc ccgcagctga cacaccacca ccgatgacga ttgttgatgg
    34681 gtttaggatt gaaccaatgt tagcacaagc gattcccaag taacgtgaga agttacggta
    34741 aacaatcaaa gcaaggtcgt ctccttcttt tgcgagatca aagacagtct tagcagttac
    34801 ttcttctccg ttatcaatca agcgtttcaa ggctgcatcg ccttcgtatt catcggcata
    34861 gcgacgagtc aagttgacaa tccctgttgc tgaagcaact gtctcaaggc agcctttttt
    34921 accacaagta catgagattg gttggtcaaa gtcaacagtg atatgaccaa gttcacctgc
    34981 tgcaccagca acaccatgaa gcaatttgcc ttctgcgaca ataccaccac caacaccagt
    35041 accgagtgtc ataaagacaa cgtctggttg gttatctcca gcacccatcc agcgctcacc
    35101 aagagctgct acgttggcat cattatcgat gaaaaatgga atgcccaaag ctttttcaat
    35161 cttttgtttg attggttgaa gggttttcca gttcaagttg taggcaccga taacagtccc
    35221 tttgtcacgg tcaaccacac ctggtgatcc cattccaatg ccttggaagt ccgctgctgc
    35281 caatccaagc aagtccaaac gatgttgaat agactcaatc atatcatcaa cgatatgact
    35341 tccctcatcc aaaatgttgg tcttgattga ccattttcct tggatttctc ctactgttgt
    35401 taagattgca aatttgatag aagttccacc aaggtcaatc ccaataatct tttgactcat
    35461 catattctcc tttttcattg tgtagtaatt gaaaatgctt acagtactag tatatcaaaa
    35521 tccattcact tatgcaaagg tttgcgtaaa tgaattataa ggaatttttt cgcctaccag
    35581 tatctgttaa tcatctaaat gatcaatggc atattgagct gcatcatttg aaaatttatc
    35641 aaaatcagaa gttaattgtc tatacatacg tttttttgac atgtggaata acgaattata
    35701 actttttgcc tttcctaaag cagcagaata ttcactattg ctatcattac tagaagaaac
    35761 tgtacttgct tgaccttcct tccaaactcc gtcagcgcca acataataac gtccaccatc
    35821 aacccattca ttgacagcca ttttaccatc cgattttaga tagtaatttc cttgccatgt
    35881 actgtaagca taagaaccat ctgatgtcaa ataataccaa gcttgatagg tggcatcata
    35941 aacccattca cctttagcca ttttaccatc tgatttcaaa tagtagtttc cttgccatgc
    36001 attgcgagca tatgaaccat ctgatttcaa gtaataccat gcttggtaag aagaatcata
    36061 aacccactca ccttgtgcca ttttaccgtt tgatttaagg taataagctc cttgccatgc
    36121 attttttgca taagaaccat ctgatgtcaa ataataccaa gcttgataag aagagtcata
    36181 aatccattca ctctgtgcca ttttaccatc agctttcagg taatagcttc cctgccatgc
    36241 atttttcact agatttccat ttccatcaaa gtagtaccaa gcgccgtcct gcttaaccca
    36301 accacttgtt gttgctgaac ttgtgttgat ttgaatagcc gttgactgtt ttgctttaaa
    36361 agcaccctta ggagcatttt tcaattcgca agccacacca tcatgatcac ggtctaactt
    36421 ggcagaataa ccaggttctc cctcgtgaat atccgaatag ccattcgccc aagcttcctt
    36481 acagctcgaa aaatggatgt tttcttccgc caaaactggt tgtgaaaaca aggctaaaat
    36541 tggcaacgtc accagactca tttttaaaaa tagacgttta ttcatttctt tctcccataa
    36601 ttatgatatc gatttcaata ttattttatc aaacttattt cagcaattca aggaaacttc
    36661 tggtcttttc tacaaactcc tttggttttg ccttattcaa gacatgaggg ccatcaggaa
    36721 tgatctgaaa ctgcgaatct gttaacagtc tatggagagc tttcatagaa ctaagattcg
    36781 gtttatcttt gctgccacaa attagtaagg ttggatagga gcaagtccct gctatatccg
    36841 ttaaatcaag tgtcttcaat tcctcagaaa ctccgaccat aagagtcttg tctgctccct
    36901 gtttttcaaa tactcttttg ggaagtagtt taaaaatcag caactgaaga taaaatagga
    36961 tattccctgc taatttaagc gggcatcctg acagaatcaa agctcgaaga tttggtaaat
    37021 cgtaactgga aagttctagt gtcagggcag cacctaagga caatccaatc aaaacaaaag
    37081 gttctgtctc ttgagctagg tgctgataaa ctcgctcttt agcttgttga tagttactaa
    37141 ctccagaagg aaataactcg atagcctcag aaggataatc tgtcagtaga ttccgaactt
    37201 ctttccaaga ctctgctgac tgccctaacc catgcaaaaa tatcaatttc atctagttct
    37261 cctcaaggct tagttcatac aagcctctca ctgcattaca gccgtaaata gcttctgctt
    37321 gggttaaatc tgccaaggtc aagactttct cttctacctg tcctgtttct agcaaatgct
    37381 gacggtaaat tcctggcaag attccaagtc ggataggcgg tgtgtagagt tttccagcga
    37441 ttttcagaac caaatttcct atagaggttt caagcagttc tcctgactta ttgtggtaaa
    37501 tcttctcttg ttctcctagg ctcaaatgcg gtcggtgagt ggttttaaag taggtaaagg
    37561 attgattcaa agcagcttcc tgaaggcaga cttgggcctg acaaaagctt gtactgagag
    37621 gggttaatac ttgacgattg acttctatct ctccagattt gctaaggctg attcgcaagc
    37681 ggtaatcttg attagcttca caatcctgac actcttcctc aatcttgtgt cccaagtctt
    37741 ctgcatcaaa aggaaaggca aaataacgac tagcttttct cagtctttcc agatgttgat
    37801 cttcaaacag caggttcttc tggctgattt cccctgtcgt aatcagttgg aagcgagctt
    37861 gtttacgata aagaactgct gccttttgat gaacctctcg gtattcagat tcccatgtgc
    37921 tatcccaagt aatccctccg ccaactccat aaatggcttg acctttgtga agttgaatgg
    37981 tacgaatggc cacattaaaa atccgtcgtc catttggaag caagagacca atcgttccac
    38041 agtagactcc acgcggttga ggctccaagt tcttgataat ctccattgtc gcaattttcg
    38101 gtgcacccgt tatggaacca caaggaaaga gtgagcggaa gatttcaaca aggtccacat
    38161 cctctcgcaa ctgactcttg atggtcgaag tcatctgcca aacagttgaa tactgctcta
    38221 cctggcacag acgctccacg tgctcgctcc caacttcaga aatacggttc atatcattgc
    38281 gcaagaggtc cacaatcatc atattttcag agcgattttt gggatcctgt tccaaccaac
    38341 tggcctgttc aagatcttct tggtcagtta ccccacgctg agtcgtcccc ttcattggtc
    38401 gtgttgtcaa ctcgcgatca ttttgctcaa aaaagagctc tgggctcatg gaaatcactg
    38461 ccatctcgtc atgttccaca taggcattgt agcccgcctc ctgctctacc accatacgat
    38521 tgtagatggc aaaaggattg gcacttaact tttgcttgag ttggacggtg tagttgacct
    38581 gataggtgtc tccctgcctc aagtgatggt gtatctgggc aatggccttt tcatagtctg
    38641 ctgcagacgt tacttcctgc caatttgagg gcaaatcaat atcctcataa gtcagaggaa
    38701 taggggaagt ttctacgcta tcatgaacag taaaataaag caggtactct cccagtaggg
    38761 gatccttgtg aactgctaat ttttcctcaa aagcaggtgc agcctcgtag ctgacatacc
    38821 ccaccacata ataaccttgc tcttggtagc tttccacttg tgccagcaaa tctgccactt
    38881 cttctacatt tctcgttttc aactctttaa taggctgggt aaaggtatat ctctccccta
    38941 aagtcctaaa atcaatcact gtttttctat gcatacctta agtatagcat aaaataagaa
    39001 aaccctcatc cgcaaagcag atgagagatt tcgattatct aaagatagaa gttttaaagc
    39061 tatctgtttg ttgaagaagt ttcttataaa cagcttcttt tagttttact gtattagtca
    39121 tagatactgt tttgtgaccg tttgcttctt gtttaagagt ttcagcatct tttttaacag
    39181 cttctttaaa tagtgtaagt aaatcatcgt atgatgaaac ggaagaacca tttacttcga
    39241 atgttgttaa tcctttcgtt gctttatctt taacttcttt gaaataagct tttttaaatt
    39301 cttcaatagt gttgaatgta ttattagata ttttcttgat aatatattca tcacttagaa
    39361 ctgactcgcc atcttttgta gattgttgtt tatatttatt cgaagtatag cctaggaatc
    39421 cgttaaggta tccgtagtaa ccccataatc taaaggcgtt atgtttgaat gaaacagctc
    39481 caggagcacc tttactagta ttacctccgt agataccggc tgtcatttca acccccacat
    39541 aaggtgattg atcgtattgg ctaacgactt caggtttata aacacggttt ccaatttgtc
    39601 tattagtcat taactgttga tctattaaac tatcaattga tgtaatattt aagttatctt
    39661 tttcttcagt tgttagattt cgaatttcgt cccactgatt taattggctg gcatctcgga
    39721 atttcttatc tattttcttg aaccatgctc catttaactc tttattattt tgattaataa
    39781 cagcatctgc ctctaaatga tcgacaagca ttaaagcatc attgtaacca cgcatatatt
    39841 tatcgatatc atcacgtgtt gtaagagatt taggatctgt atcgtaccat tgattaccat
    39901 cattaggttt tttgaatacg gtattcagac ctaatgaacc atattcgtta aatccacttc
    39961 ctgggactgg tagttgtaac ataccttgag caaatgcttc agcatcagta ccttcacgac
    40021 gtccaaaacc acccaaatag attttacgat cgtttatatg tgttgtttca tgagtatata
    40081 cagaaatacc ataatcccca atcatattta gagcaacata acttacatca gaacgaggat
    40141 ccattggatt atcataaagt gcagcatatg ctcctgttcc attataacca taatattttt
    40201 ctataggtcc aaagaattct ctaagaggag tatatacatt gtcagtatta tatcgaccgt
    40261 atttttcaac ccagccacct ggcgcattat aaccttccca gataggaatc acagtatctc
    40321 ttagtagata ttgtttaaca ttatctggaa ctagacgata ccaaaaatca tagtagtttc
    40381 tgtacccatc agcagcataa tcaacagatg ctttaatgtc ttctaatgat ttttttccta
    40441 atttctcagc actaccaatt gcaattgcgt tgtagttaga ggcaataaac atgtgtgatt
    40501 tagttatatt caataatggt aaaatcattt ttctgtgctg agctacgttt aagttagcat
    40561 atgctctata tttagcattt ttaatttctt cgacctcaga tgcgcgttct gcgatgtaga
    40621 catggtcttt tgtagcatca ataaaccaat cattcatatt atctatattt gtgaataatt
    40681 gtctattata atttaagaat acatctaaat tacctgattt agtatattta gctaatactt
    40741 caccgaatgc gtcgaatgta cgtgaacctt taatgttgtt ctctttagag ccgatttcaa
    40801 ttaatctgtc taatacgcta actttttcac catagaagtc tggtttgaat aacattaatt
    40861 ctttaatatt aacatcaccg aatttaacac cgtagtaacg gtttaagtat gttaaaccta
    40921 ataatagggc agctttgttt ttctcgactt tatcacgaag catttgacga gcagctggag
    40981 aatcatttaa ctggtgttct tcattttgaa ctaattttgt gattaggttt gttaagttct
    41041 ttttaacggc tgtgaagctt tcttctaaat ataaatcttt gattgcatta actctatagt
    41101 cacctaatcg atttaggtgt tgatacattg tttgagattg aagatctact ggttctaaaa
    41161 tagattttat gtcattaaca agagtagtgt tatctttttg cacgatattg ggtgtatatt
    41221 taattcctag gtcagttata gtatattctt ttacattact taaaccttca ctgctagaag
    41281 ataagttaaa gtaatctttt gtaccgtctg catagtgaac aataatttta ttagcttcat
    41341 ctaggtttgt gataaactca ttgttgttca tcgctgtaac agaaaggact tctttagtat
    41401 ttagagggtg ttctttattt aatttattac cttggtatac aatataatct ttattgtaga
    41461 atggtattaa tttttcaagg tttttatagg cttgattata ttcagcgttg taatcttgaa
    41521 tactagaata agctttttct tcattaagtt ttgcaagagg agatagctca ctttctaatt
    41581 tatcagcagt aatattgaaa gtagcaactt tagcatcagc ttgttcttta gttaattgtt
    41641 ttattttttg cagattggta aaattattag ctccactgct agcgccgttg actctataaa
    41701 tatcagataa gaattggcgt gcatctccgt cattaatttc gtttgaacca tatacttctt
    41761 cacctttaat tactttagca taggtaacaa tatcttttat aactccccaa ggccaagttt
    41821 tagctacaac accaccaaca aaacgagtat ttttaacatc taaagttcct ttagcaaccg
    41881 aattggtaac ttttgactta gttccatact gatagctatt taacatatat gtaaccaaag
    41941 gaactagcat acttgcgctt gcgttagcgg cagtaatgtt agcatcaaca taagctttat
    42001 taacaaatcc catgtagttc gaaccagcaa ttcctccgac tgtagaatta ttaccaacag
    42061 aattgatatt acctataaat gctacgtttt ctagagcagc attttctttg atattgttta
    42121 caaatccagc aacgttattt ctggctgtta tcgttccagt tgctttgatg ttttctatac
    42181 gtgtggttcc gttgatttca ttcgcaattg tcgcgatatt atcttgatta gacacattaa
    42241 tatcaatatt ttcaaaattt atatttttaa cagttccagc tttaatcttg tcaaataatg
    42301 gatgttccaa ttcagtaata gcaaattgtt ttccttcaga acttaaaagt tttcctgtga
    42361 attctttagt gatatatgat tttccattag gaacaacatt tctagcgctc attgattgtc
    42421 ccagacgata ttcttttgaa ggatcgtttt gaatagcttc cactaattct ttgaaattat
    42481 aatatacatt atcttcgtgg actttaggtt tttcaatata gtgaacgtat tcttcttcaa
    42541 atttattatc agcagttcta gagactaaat tgtctgcgat tgctgtaact ttatatacat
    42601 gtgttccgtt aaccgtagtt tcttctatat ttttaacagc tagtaatgta gttttctgat
    42661 tatttgaagt tatttttaaa taataattgc tcttatcatc aggaatagtt gttatcagtg
    42721 attcattagt ttcttttcca ttttcgtatt tgattaaatc tgtacgttta atatttttaa
    42781 gctcaacttt tttaagatct aattgaatat tttgattttc tagagtttca gtttcttcac
    42841 cgttacctct gtcgtaaatc atagttgtag atagggtgta ttctttgtag tactctaggt
    42901 tcttaaatgc agcgcttata gtttctgttg ttaccttgtc atctgtaaga actacagtat
    42961 taataacttc ttctcctttt ttcaactcag ctgtgattga tttgattttt gttttgtttt
    43021 gattttctag agtatactta gcaacagctt cacgttccaa tattttctta tcggtactag
    43081 tcaatgttaa tattggcttt tcagataatt caaccaattt ttcaatagtt gcagttaatt
    43141 tttcaacagc ttcgttaact tcactttgtt tagcatctgt attagctgca actttttcag
    43201 cctttgtaac ttcagtttgg aggttttgcc aacttctatc actgtaatgt tcttttacct
    43261 ttgtttttgc atctgcaatc gtattgttta attcagtttt atcaacgttt agagcgtcaa
    43321 tagccgtttt aagtttattt gtctcgctat ttacctcagg ctgttttaca ggctctgaag
    43381 catagacacc ttttgcagtt tctaaaacag gtccaagagc attgtaactt gctgtagaat
    43441 aatcagtagg agaaactgaa ctagctttat caatttgatt atttaactca cttttatcaa
    43501 ctggttcttt agtaccaata ccctttattt tatcttctgg tttcggtgtt tcctctacag
    43561 ccttctcttc ttcaggaact tctggttgct tttctggctc aactggtgcc gttggtgcct
    43621 gttcgtcttc tcttggcgcg actggttcac ctgcttgttc aacttttggt tcctctgttg
    43681 gttctgtttg tttttctaca gcaggcgttt caacttttgg ttgttcaata gattgattaa
    43741 cagtctcctc ttttggttct acagtttctt cagccttggt atctggagtt gactcttctt
    43801 gtttcggtgt ttcctctaca gccttctctt cttcaggagc ttctggttga ttttctggct
    43861 cgactggtgc ctgttcgtct tttcttggcg cgactggttc acctgcttgt tcaacttttg
    43921 attcctcagc tggtttgtct gatggttgac tttctggctt aactgctact ttttcctctg
    43981 gttttgactc aacttctcca cctacttctt caactggagc tggttctgct gaatcttctt
    44041 tcccctcttc tactttagga agggtgtcgt cagtaggttt tacctccgat tttggttctt
    44101 cctttggact ttcttctgtt ttaggtgctt cttcttttgg agcttcctct gtctctacta
    44161 cttggttttc tgtcctagct tgctcctgat ttgttgttga ttgaggagtc tcaacttcga
    44221 ctacagtcac ctctccaggt tttgctgagg tttcttctaa aacagtgtcc aagccaagcg
    44281 ttttgaggat gtcacctgat agataaccaa catagcgata gccctccatt tcaacaacac
    44341 cctctcgact agccagtgct agggtcgcaa ctgggtttac agcccctgca ctaggaagaa
    44401 ctaccaatcc catagttcca actagaaaga cgctagcaat tttctttctc ttgtagatta
    44461 aaagcaagct cccaacagtc agcaaaccaa aagctgtcaa aacagatgct tctgtccctg
    44521 tttgaggcaa ctgatctttt tgatacacca aaccatatac aacttcattc ctgtcaggct
    44581 ttcctgtctg aattaaatct ttagcttctt gtgaaataat ctctttattt acatagtgat
    44641 aggtggctgc gtccactaca gaaggagcca tcaaaaggct tccaagaaat acagagccta
    44701 caactccctt aatcttacga attgaaaaac ggtctttttt aaacactttt atctccttta
    44761 ttcattctca aaacttccta atagcatctt gcggatagtg cgcacgcgca cctccgatta
    44821 attttggacg actagtcagt gccgttacat gggcatgacc aatctctctc aaaatagggc
    44881 gaatcggaac ctgaacatgc ttgacatgca tgccaattgc agtgtctccg atatccaatc
    44941 cagcatgagc cttgataaat tcaacctcaa ctggatcctg cataaactta aaggctgcca
    45001 actgccccga acctcctgca tgaagagtag gatggacact gacaatttcc agaccaaact
    45061 gctctgccac ctgacgttca acaacgagag cccgattgac atgctcacaa ccttgaactg
    45121 ctaaatggat acctctacta cctagaatac ccaagatagt ctccactatc agctcaccaa
    45181 tctcttgact ggattctttc ccaatctgac cacctagcac ctcactagaa gatagaccta
    45241 aaacaaaaag ggccccctgt ttcaaattgg tcttttctaa aacatcttcc actacctgac
    45301 gtgtttctct ttgaatctgt gtctcgttca tctctgttac ctctgttgtc actcttctat
    45361 cataccgttt tttcttgttt ttagcaagat agacaaccta gaaagtttgc ccaattacgc
    45421 ataaaactcc cagaattgac tgggagttag ctagtttcta ttctatttat atatatttca
    45481 actttcgttc ctttttgggg tctagaatca atcttcatct ggtaattggc tccaaaatga
    45541 agtttgagcc gttgatcgac attttgaaga ccaactcccc cacgtttgag ttgactttga
    45601 ctactatcac cagcatcttg gaagccaacg ccatcatcct caatacggat gaccaatccc
    45661 gaatcctgtt tctggacaga aagtttaata tggccctgac cttccttttc cttaatgcca
    45721 tggtaaagag cattttctac aaggggttgt aggaccagct tgggtaagac taaattatca
    45781 aaggcaacat tttcattaat ttcgtattcc agcttatctc catagcgttg tttctggata
    45841 aagagatact ggcggacatg attgatttcg tcagagagac aaatcaagtc cttgccttga
    45901 ttgagcgcca agcggaaata ggttgccaag gacttggtca cctgcaccac tcgctgacta
    45961 tcatgaaatt cagccatcca gatgatggtg tccaaagtgt tatagaggaa atgtggatta
    46021 atctggctcg aaagggcttg aagttggtac tgacgggtcg tttcttcctg gctacgaata
    46081 gctaccatca actgatcaat ctgatccaac atggcattaa attggcgagt tacttctctc
    46141 agttcatagg caccaacttc cttggcacga agattttgag caccagaagc aatttccaac
    46201 atggtttctc tcaaatcctt caaaggagca atccagcgtt taagactgaa ccacactaag
    46261 cagagacaga caagaagaga tgtgacactg gccccaagca aggtccacaa gagctgactc
    46321 cgaacctggt ctaacttttc caatgatgac acgccaagta ccgtccaatc agttcctgca
    46381 atcttctctt gactgacgta ggatttgtga ccaggagtat aaccctgacc tgtctcgatg
    46441 tagggtttca tagcctccat tttgctagac gaactataaa ctgtgtgttg aggatggtag
    46501 acaaattcat ggttttcatt gataatgaag gcaaagccct gctgccccaa ctggagttga
    46561 ttgagatagg cttccagagt ttcataagaa atatccaaac gaagcacacc aagattggct
    46621 ccctttgcat caacaagttc ttgagtgaca gaaatgaccc actgactatc tgatttacga
    46681 gctggagtca aaacaggcat agctccctga tgaatagcct tttggtacca atcctcagcc
    46741 atcatatcag aggaagtttt catctgcaca ctgtcatctg tagaaatgac ctgaccagat
    46801 ttggtcacca gcacaacagt tttcaagtcc ttatctgact tcaagatggt caaaaacaaa
    46861 tctcggattc cctcgacctt gtcttgactg ggattctcag cataggccag aacatccgtc
    46921 tgctgggtca aaccagtcga ggtggtttct agttttttga tataagactg aataaagtgg
    46981 ctagtctggc tgatggtcgt ttggctgttg ccctcaatgg tggcctcaat ggctgaagaa
    47041 cttgattgat agtagaaagt tccaaccaga gctaggagaa tgagaaagac cagaaagatg
    47101 gaaataacca ttctaactaa aagagaagaa cgcttcatcg gtcttctccc ttcttaaact
    47161 gacgaggtgt cacacctgca atctgcttaa aacgttgggt aaaatagttc atatcttcaa
    47221 aaccaacctt ctctgcgatc tcataaatct tcagatctgt agttaaaagc aagagcttgg
    47281 cttgtttaac acgttctctc accagataat cctgaaaagg caagcccaac tctttcttaa
    47341 tcaaggaact cagataggtc ggactaaaac ctaagtcact ggctaaagac tttaaactaa
    47401 attggctatc agccagatga gactggattt tctgggccat gtttccttca aacctattag
    47461 tcaataaatc ttgtaactgc tcttctttct cttccttgtc tagtttttgt ttgattttcc
    47521 ccaacatttc ctcaatatcc tgacgagaaa agggtttgag caggtagtcg tccacaccta
    47581 gtttgacagc agacaaggca taatcaaaat catcgtaacc tgttaaaaag accaaatgaa
    47641 cctgaggata ggtttctcgt accagactgg ccaactggat gccatttaga tgaggcatgt
    47701 tgatatcggt taaaatgata tctggcacct gcttttggat caattcccaa gcctgccttc
    47761 cattttcagc ctgaccgatg atttccatat cgtaggctgc tacattgacc agtttagtca
    47821 aaccttgtct taccagatat tcatcttcta cgattaagat tgtgtaggtc atgctctgct
    47881 cctttaccac ttactagtat cagtatagca aaattctcct ctaactgctt aggaaagacc
    47941 tcttatactc aataaaaatc aaaaagtaaa ctaggaagat agccacaggt ttctcaaagt
    48001 atagctttga ggttgtaaat aaaactgacg aagtcagctc aaagtatagc tttgaggttg
    48061 tagataaaac tgacgaagtc agtaacccta catacggtaa ggcgacgctg acgtggtttg
    48121 aagagatttt cgaagagtat taatcaacat aatctagtaa ataagcgtag cctttttctt
    48181 ccatttggtc tttgggaata aagcggatag agaggctatt gatacagtaa cgtaagccgc
    48241 ccttgtcctg tggaccatcc gtaaagacat gcccaaggtg agaatctcct actcggctcc
    48301 gcacttccat acgcgtcata ttgtaggact tatcttcctt gtaggtgaca acatctggac
    48361 tgatgggttg ggtaaaacta ggccagccac aaccagactc aaatttgtct tttgatgaaa
    48421 agagaggttc cccagttgct atatccacat agataccgga ttcaaattta tcccagtaac
    48481 ggtttgagaa agctcgttct gtttgatttt cctgggtaac tgcatactcc tcaggtgaca
    48541 gggtcttttt caattcctca tcacttggtt ttggatattt gctggcatca atgacaggat
    48601 aggccgcctg attaacattg atatggcagt agccatttgg atttttcttg agatagtctt
    48661 gatggtaatc ctcagccacc acaaaattct tcaagttttc cttttcaact gctagaggtt
    48721 gatcgtattt cttagccacc tcatcaaaga cttggttaat cacttccaaa tccttgtcat
    48781 ctgtgtaata aacaccagta cggtactggg tccccacatc atttccttgt ttatttttgc
    48841 tggttggatt gataatgcgg aaatagtgaa gcaggatttc cttgagagaa atttgcttgg
    48901 catcataggt gacatggacg gtttctgcat gacctgtttg gttaatcaat tcgtacttgg
    48961 ttgtttctcc tctaccattt gcatagcctg aaacggcatc cgtcaccccg ggaacacgtg
    49021 agaaatattc ctccactccc cagaaacaac ctccagctag ataaatttcg tgcaagtctg
    49081 cgtctttact aatttctgtt tttttcactg cttttcctcc ttggctaact gccgcctttt
    49141 caatttgcga ggcatctgtc tgccctgcat ttcgtatcaa tagaacatag aaaccggtta
    49201 tggctagaaa aaatactcct agcaacaaga agatttttaa cttatcattc ataagacgcc
    49261 tcctaggcta attccttcaa agtttgcaaa attgcatctt tttccatgaa tcctggatgt
    49321 gttttgacca gcttgccttc tttgtctata aaggcttggg ttgggtaaga acggacacca
    49381 taagtttcca aaagtttgcc tgatgggtca actaggactg ggagattttt ataatccaat
    49441 cccttatacc aattcttaaa gtccgcttca gattgctctc ccttatgtcc tggtgacact
    49501 actgtcaaga ccacatagtc atcaccagct tctttagcaa tctcatccgt atctggaaga
    49561 ctagccagac agatggaaca ccaagaagcc cagaatttga gatagacttt cttgcccttg
    49621 taatcagata aacggtaggt cttgccatct actcccatca attcaaaatc agccacctct
    49681 ttccctttag ctgcgcttgt tttactagct gtctgctccg tcttcatttc atctttcgtt
    49741 tggtgttcac tagtcacgga cttgcctgaa caagccgtca aacaaaggag cgaacctgct
    49801 ccaagaacac atgtttgcca ttttttcata ttgatattcc tttccatttt attcaaataa
    49861 ttgacttaaa attgaagcat ttccaaacag aaccaagaat cccatcacaa taatgagaaa
    49921 accacccact tttttgagga ttccgagata gggatgaagt tttcggaaat gtttcaaaac
    49981 ataactagag gtcagagcta gaagcaagaa tggtagcgcc aagcccagcg tatacaccaa
    50041 catgagacca gctccctgcc aagctcctga accacctgaa gccgccaagg ccaaaacaga
    50101 ccccagaacc ggccccacgc aaggcgtcca agcaaaacta aaggtcaagc ccaataaaaa
    50161 tgcctgacta tagcccttac cattttgccc ctgtccttgc agttgtagcc tcttttcctt
    50221 ataaagcccc ttaaagtgta gaatctccat ttggtgcaaa ccaagaagga taataattgc
    50281 cccagtaaga tattggaacc aagaagcata aagcaaatcg cctaaaaaac cagctccata
    50341 gcccaacaaa ataaatataa aggaaattcc tgctataaag gccagagttc gtaataaact
    50401 agtaactgag attgaaaatt tgccgctaga agcctgagca ccatccttat catctagtaa
    50461 cactcctgta tagaccggta acaaaggtaa gatacaagga gaaaagaagg atagaatccc
    50521 tgccaaaaag acacttagaa aaaagaaaat atgacccata aagttcctcc tatcatttta
    50581 ttgatagatt tattatactc cttccatttt cgaaaaaaca gggacaatga taggggaaaa
    50641 taggaattta atcagatgat ttagaaatct tggacaaaaa ctatacaaaa aactgtcaaa
    50701 gcacaaaagc gcatagtatc aagattctat aaagccttga tactatgcgc ttttgtaatg
    50761 gataaatagt tagtcttttt taaagacctg atctttcaaa ctctgcatac tggcattgat
    50821 caccgcgcct aggataacaa ttttagcaat caagataaac caaaacatca taacaacaag
    50881 aagaacggaa cctaaaattc ggacatccac caaatgatgg acatagtaat tgagataact
    50941 agagaacaga gttagtacac ctaaaatcac caagagaaca aaggcactgc ctggtagggt
    51001 atagctaatt ttcctgttag atagattggg aagaaaataa taaagcatga ccaagatagc
    51061 aaagaggagg gcgtaaatca gaggacctgc caacccttgt aaagcctgat agataatgcc
    51121 atcttttgtc caataatgag caagtaaagc caaaatcatc tgaccaaata agatcaaaaa
    51181 caaggcaaac gcaaagagga actgcaagcc aaaactgact aggagactta gcatctgatg
    51241 ggaaataagt ccacgactct tttcgacgcc ataagccttg ttaaaagctt tttgcaagaa
    51301 atttatagat tttgaaaaac tccataacgc cgataaaaca gaaaaactca ataaacctgt
    51361 tgaaggttgc gtcaagactt ctctggctat tttttccaca ccttcataga ggcttggggg
    51421 caggacgtct ttcataaagc ccagaaattc tcccacagga atctgaaaat aggggaggat
    51481 attgaccacc accaaaagca gggggaaaat cgaaatcaac caatagtagg ctactgcgac
    51541 actggtcaac tcactatctg atgcttgata ataatgcaaa aaagctttta ataaaggctt
    51601 gtctatcagc tctttccacc actttttcat gtcatactcc ttcatttata atcttatact
    51661 caatgaaaat caaagagcaa actagaaagc tagccgcaag ctgctcaaaa cactgttttg
    51721 aggttgtaga taagactgac gaagtcagtc acatacatac ggtaaggcga cgctgacgtg
    51781 gtttgaagag attttcgaag agtattaact aatttcttct taccaattcc accatatcat
    51841 acggcagggt attggcagct tccttcaagg aatagttctc taagttattt acattttgtc
    51901 gtaatttctt ggcatactta gttgtaatta atcgtttttc ttcgtattcg aaaatcaact
    51961 tgcgctccag ataatagcct ctcagcattt cattgatatt gttgggtttg acacgattga
    52021 taacccgttc gacaaaggca ccactgctga taatagttgt ttctcgaaga cgagactcct
    52081 gcataaaact aatcaaagag cgtctgtaga ctcccttcag gttttccaaa ctttcaataa
    52141 tcatctccgt attggcaaga tagagctctg caatttggtc ataatcaaga gcacggagac
    52201 ggctttgctc cttgtccttc cagctacgga aggtctttcc aagagtaaaa acttcatgaa
    52261 ggagaaaacg taaaatcctc aaggaaacaa gaaaataata ggtcagtctt gaggcaagtt
    52321 tacgattgat tccttgttct atatttttca gataacgttg gtaaactcgg taagcacgat
    52381 tgctaatgtt cccctcttca taggcctgtt ccaaaccatc actttcaata ctaagaatca
    52441 agagtttcaa agcagcccag tcttcttgat catcctggtt ttcttggctt aaaatgagat
    52501 tttcaatacg tccatgataa ttgtcaatag ccgcatagag gggaagttta tttctggtgt
    52561 cttccaactc tttttccaac tctagcgtta cttcattcaa aatggcgata tgcatgagat
    52621 aatccttgct ttcttcctct tcatcagaaa gatgaggcaa gatcaagaga cctgttaaaa
    52681 agctgacaag cgtcacacct gcaacaagga aaagcaaaag aggatactct tgttctagat
    52741 tacttggtat caagagaatc gtagcaatcg acaccgttcc cttaacacct gaaaaggtca
    52801 agagaaacat gtccttcata tacttattta gctttttctt gaggcgtcgg gttctatagg
    52861 cataatagcc atagatcata ataaaacgaa tgacaaagag gacaaaggta agggcgatga
    52921 gagatagcaa taaaagtaga ggattataga ttggattggt caagataggt tctgctatca
    52981 tttccaactc catccctaaa atcacaaaga cagaaccgtt gagcataaag gtcactgtat
    53041 gccagaccgt ctcggtcacc gtatccactt gggcttcgag gagcgtgatt ttcttgaaac
    53101 gacttgcctt taaaattcca gcaactacga cggcaataat ccctgaaaca tgaacttctt
    53161 ctgccagaaa gaaggtcact agaggcaaac ttaattctaa taaaagttca ctggcaatat
    53221 ccgttgcgcg cacacttagc aagaaggtat ggaggaagcg gttggtcatg gctgttaaaa
    53281 atccaattaa aaaaccgcct aggattgaaa agatgagcga actgctagct tgccccagag
    53341 aaaaagctcc agttgtccaa gctgtcaaag ctacctgaaa agccaccaaa ccagaagcat
    53401 cattcaagag tccttcgccc ttaagaatat tggacacgcg cttaggaaag ctaaaacgct
    53461 ccgaaagaga ggcaaaggcc accaagtccg taggaccaag ggctgcccca acagccaagc
    53521 aagctgccaa gggaaggctg aaccaaagaa gatgggccaa gccacccaaa ctcagggtcg
    53581 agataaaaat cactggaaat atgagataaa caatgattcg ccagtgtttt aaaatagccg
    53641 taacatctgc ttcttcagcc tctcggaaaa gcaagggtcc gataaccagg gccaaaaaca
    53701 actccgtatt gaggtgaaag tcggtattgg gtaaaaagag accaatcaca attcccaaaa
    53761 gaatttgcac caaagggaga ggcaaaaagg gcaggagctt attggttgta cttgagacaa
    53821 tcaaaaccag taaaaatagg atgaggtaaa tcagtaattc cacgcacgtc ctccttaatc
    53881 ttttttacaa caggattcaa atatctcctt ctgctctttg attttttggt caatcttgga
    53941 acagtctttg tgctcaattt ttctctggca ccgttccatt tcaagagcaa ctaatttttt
    54001 cttgatttta agcatttttt tgctcatatg cgcttggtct agcacgccca ccgatcgttc
    54061 gtggtgggtt gattcaacaa aattctggcg catggcatcc agcttttcgt gtaggtattg
    54121 tttatccatg tctgtatctc tctaattttt caatcatcac taaaaacggc gggttgttga
    54181 cttggtttaa agttcggtaa atggcagctg tgtactcttg ttggttcaac tggattacaa
    54241 aatccaagac agcatctctc tcgaggtcgc ctccttcatg accatagtaa atcataatag
    54301 caattcgtcc acccttgaca agtaagccac atagcttttc taatgcctca atcgttgtct
    54361 gcggtcgggt gatgacagac ttatcagctg acggcaaata gcccaaatta aaaatccctg
    54421 ccttagcttt tgtcacaaac tggtccagtg tctcatggcc ttgcaagatt aactgggcat
    54481 ttgtcaagcc agcctgatgc aaacgctctt gggtcttttc caaggcttgc ttctgaatat
    54541 caaaggcata gacttgcttg gctagcttgg ctaaaaaaag cgtgtcatga ccatttccca
    54601 tagtcgcatc cactacgaca tcctcttttg tcacgacctc agccaaaaaa tcatgtgcca
    54661 tctcaagtgg tcttttcatt ttcaaactcc tgttttacag ccttgcatcc ttgaacactt
    54721 ccacgacgtc gcatctccat ctcaatgctg ttgagagctt cccatttatt gaggctccac
    54781 ataagcccaa tcagcatatc cctaggtgca tctcctgtga ttcgatggat gacgatatgt
    54841 ttgggaatga tttccagttg gtcacagatg accctgacat attcgtcctg actcatcaat
    54901 tgtaaacgtc cctcatggta atctcgttgc atacgagtat ttgtcataag atggagcaaa
    54961 tgcagtttaa tcccttgaat atcgttattc gtgacacaac ggcggacatt ttcaaccatc
    55021 atctcatggg tttcaccagg caaaccatta atcaaatggg aaacaatctc aatcttggga
    55081 tactttctca aacgcttgac cgtttccacc tacaattcat aagaatacgc acggttaatc
    55141 aggtcagaag ttgcttcata agtagtctac aagcccaatt caaccgtcac atgcatgcac
    55201 tccgataact cagccaaata ttcgatggtt tcgtctggta aacagtctgg gcgcattcca
    55261 atattgattc ctaccacacc tggctcattg atagcctgtt cataacgctc tcgaataact
    55321 tccacctttt catgggtgtt ggtaaaattt tgaaaataaa ccagatactt ctgaacatcc
    55381 ggccacttac ggtgcataaa gtcaatttcc ttataaaatt gctcacggat aggcgcatct
    55441 ggggctacaa tagtatctcc agaacctgaa accgtacaaa aagtacagcc tccatgagcc
    55501 acagttccat cacgattggg acagtcaaat tccgcatcaa tagggacttt aaaagtcttt
    55561 tctccaaaga gttttcgata ataatcattc aaggtattat aagattttat aactttcatt
    55621 ataacaaaaa tcacccacaa tctcaaaagc ctgactttcc tataaattcc tctgtttctc
    55681 gtttccatta gctttttttt atgatacaat atgggtatga ttttaatgaa attagcatct
    55741 attttattat tgatactgac cttagtcgtc tgcattatcc taaccaaact ttttagatta
    55801 aaaaaactag gacgaaactt tgcggatttg gcttttccgg tcttggtatt tgaatattac
    55861 ctgattacag ctaaaacctt tacccataat ttcctcccta gactggggct agccctctca
    55921 atcctagcca ttattctcgt ctttttcttc cttttgaaaa aactcagctt ttactatcct
    55981 aaattcatca aattcttctg gcgtgcagga ttcttattaa cccttatcat gtatatagaa
    56041 atgattgttg aattgttctt aatgaaatag tcgaatccct aagcattttc tagggatttt
    56101 tgctttctct acaaaatagt atagacaata acactataca attttataca aagaaaagag
    56161 tctgggacaa tagtctctta tctccaaaaa aagcaacgga tttgccgttg ctttttttgc
    56221 atggttacga tagtcttggt aaaatagaat tgcccaataa accatttaga aaggctatcc
    56281 catgcatatt cactataaca caaatcaaac aactttacca ctagaaatca gttccttctt
    56341 accacaagac catctcgtct ttactattga aaaagtggtg aataccttgg aggaacatca
    56401 cttctacgcc ttctatcatg cctttgatcg cccgtcttat caccttaaaa tgcttgtatc
    56461 tactcttcta tttgcctatt cacaagggat tttctctggt cgaaaaattg aaaaatggaa
    56521 gagttagtga ccttagattg tttgtttatt gacggaacta agattgaagc caatgccaac
    56581 aagtatagtt ttgtgtggaa gaaaacgaca gagaaattct ccgccaaact tcaagaacag
    56641 atacaggtct attttcaaga agaaatcctc cccttctgat taaatatgcc atgtttgata
    56701 agaaacaaaa gagaggacat aaacagtcag ctaaaaactt agcgaattgg cactataatg
    56761 acaaggagga tagctacaca catcctgatg gctggtatta tcgttttcac cataccaaac
    56821 atcagaaaac acagacagac tttcaacagg aaatcaaggt ttactacgct gatgaacctg
    56881 aatcagtccc tcaaaaggga ctgtatatga acgaacgcta tcaaaacttg aaagctaaag
    56941 aatgtcaggc gcttttatct cctgaaggta gacagatttc gctcaacgca agattgatgt
    57001 gaaacctgtc tttgggcaga taaaggcttg tttgggttac aagagatgta atctgagagg
    57061 gaagcgtcaa gtgagaattg acatgggatt ggtacttatg gccaataacc tcctaaaaca
    57121 tagtgaaatg aaataagacc aggacaaatc gataaggaca gtcaaattga tttctaacaa
    57181 tgttttagaa gtagaagtgt actattctag tttcaatcta ctatacaata agagaacgac
    57241 tcaaaattaa aaagctagag ttccgcaatt ggaaatatct agcttttttg tggttgagaa
    57301 ctattttgtt ccagactctt tatcttctat ttaggacaag agtttttctt tggtctttaa
    57361 tgataaagaa ggtatcaaaa tttctagtct tcttttttac ctttagtaac tactaatcct
    57421 gcactcaaac ctagaagagc taaacctgct gctactgctg cttggcttgc cgcactacct
    57481 gtatttggta actgggcttt attagtttga tcagcttcac ttgaatcaat tggttttgta
    57541 tctgcttttt ctgacacttg tggtttttta gcttcttgag ctactggttt ggttccaacc
    57601 aagacgatgc ggtctgtcgg aacttctacc acttcacgga gtttttcttc cttacttcca
    57661 tcaggattaa tcactgtaaa gatacgttct tttccaactt ttccttcttg ttctacacga
    57721 gtttcaccta gatacagtgt tgaatctttt ttctcaactg tcttgtaggc caaatctttt
    57781 tcaacaaatt cgagttttgg aagatcttct tgtacagcag aaactggttt ttccttagtc
    57841 aactgaatac ggtattcctt gacttgtttt ccactttctg aaacgaggcg aacaagtact
    57901 ggaaggctat cttctccact atctaccaca gttgaagcta cttgattgtt ttcttcaact
    57961 gagacttttg gccgttgacc tttataggta atttgatagt cttgacgatt ttcagcgaaa
    58021 tcagcaagtt cttttccatc tacaagaatc tttgattgcg tgctttcttg aggcaattca
    58081 cttggtgcaa ggaaggtcat ctcaatcatc gcaacaccgc tcttgtcagc tttacgctcc
    58141 atacgccatc tcatggcttt ggctttgaca gctttaaatg ttacgttgat ttcatcacca
    58201 gctgcgatgt ctttatccgc acgataaggc acagcttccc aattttctgg attgttaaat
    58261 ggatgtccag attcgtaggc ttggtagttt gaatagtagg taggtacttc aaagcctggg
    58321 ccgacatagc gttctaaaac gagtttagat ggtgcatccg taccactatc tgcaaagaag
    58381 tgaagtttgg cttgagcaac agtccgttct acaatcttac cattttcacg gaagatcaca
    58441 cccgctgata cttctggatt agaagatggt gttggtgacc agtttgtcca acgacgattt
    58501 tctgaatgat ctccgtcatt gagatagtca acgcggtcat gagagttttt gtcaatatca
    58561 ttggttgctg aagcaaaggc ctggttactg ttttcatcat agttagggtt atctgaaaga
    58621 gtctcaccaa gtttgtctgt cactcgtaca gtgacctcag caacaaggtt actaccaagg
    58681 acacggcctc gaacagtaaa ttgacctgct tttgtcagat tttccgctgg aacttcttcc
    58741 cattcaactg tcaggtcttt tgtttcgtag ccgtctttac ctgtgaagta aactggaacc
    58801 ttagtcggca attcaagtgc ttgacctact tgtagcaagc gagcttgttt aaccgcagca
    58861 actggtttat gagaaagtaa gttcttatcc ttagtgaagt gcagacggta ttctcctaag
    58921 atgtcgccat tttcagcttt cgcgatgaca cgaactggct caccttcacg aacgcttgga
    58981 acgacggtag cgagaccatt gttgctaaca tttgctgtga ctgccggaac ttttccatct
    59041 acagactcaa ggtagtagtc tgtcaaatca gggttgaagt ttgctaagtc tttgccgtca
    59101 acttggattc ttgtttgtcc ttgtttggct gccgcaactt gtttcgcaaa gatttgtacc
    59161 tctgtgatag acgttccacg cttgttatct gctttaacca tgcgaatacg aatagcatag
    59221 gtttcaactt tatcaaagct aaagtggttc atttctccag ccttgagttg agcaggggct
    59281 tttagattag taactggttt ccagttggca gaatcattaa agacatggtc ctcattacca
    59341 acaaaactag ggtttttagg agctgttggg acagtcttac caacataata ctcaatcaca
    59401 taagacttcg gtgcaccaac tccatggtct tcgtggaatc cgacacttag attatcaacg
    59461 gagcgtttgc tcaagatacc tgaatctcca aacagaacac cgactgaagc ttctggatta
    59521 ctacgattcc agtttgtcca acgattggct ggttggttat tgtaggaaat gagcttgtca
    59581 ttaacatttg aaactgggtc gcttggattt gaatctgaag caaaggcaag tggcaattct
    59641 gaaccggtcc attggtcaga aatgtttgca ccttgctcag tttgagcaga tacgcgaaca
    59701 tgaagtttag ttgttaattg agtaccttct aagcgaccat taactgtaaa gacaccttcc
    59761 ttagcgtatt gctctggacg aatcgcatcc catgcaacct tagctgatga aacgtgacca
    59821 tttgaatcat atgtccgaac actttctggt aattgtggtg cttctgcgat tggagttgtc
    59881 acactgactt cttcaactga aacgatacct tctacagaga cttttgcacg cgcttcaagg
    59941 tcaattcctt caactttacc tagtacttca aatgtttgat aggagtctag tttttctttc
    60001 ggaatagctt gccaagtgac tttatgagtt ttagggaaac ctttgtcata ctcaactgtt
    60061 actgttgctg gaagacttgg ttcctgatgc aaatctgtca ctacatttac aggacggatg
    60121 gattgcgcaa tcttcttctc agtattggct tggatagtga gttcaacttg gcctttagct
    60181 ccctcatatt cagcgttcag agtgactgct cctggcttat gcaactcaag cattccttta
    60241 cgaattgcga cttccccttc accacttgta gagaaggtta ctttatcagc tggtaataca
    60301 gcttgcgttc catcttgata gtgagctcga accgacaatt tgacagtttg gtcttctttg
    60361 agactgtcag ctttttccac ttgcaagctc aagtgagcaa tttttggcgc ttcttcaagg
    60421 aattgaattg cataggtttg aagagggcca ccatctttag gctgaataaa gatgctcgca
    60481 cgcatgccgt ttgctgcgct tgcttgaaga actgtaacag ctgcattttt agcacttgct
    60541 gtgacttctg gcaacttagc tccataagca agagtgcggt attgcattgg tttttgacta
    60601 gtaagacctg tgacagcttc accaccaacc gttacagttg gtactgcagg tgccgcagga
    60661 ttgccttctt ctaccacaag ggttgcatga attggttgac cttctaaata accggtcgct
    60721 tgaatacgag aacctggaat tgctaactta gctttatctt cttcggcaat ctcccacttg
    60781 tccacttcat actcttcaac acttccatca gtcaaaacat aggaaacaga tttgtctaca
    60841 gaattcaagt cagtatttgg agcaatacgt ttcacaactg gtagctctga tttaagagca
    60901 atcacttcta cacgagcttc tacttctcgt ccgtcagcca tacctttcac cgttacaata
    60961 ccaggcttgc tcacatctac tgaagaccag gttacaggac gttctgcacg gctaccatca
    61021 ctgtatacaa acggaacagt ggtaggcatt tcaggtgcct ctccaataat ggtctgtact
    61081 tttggcactt ctgtccccaa aacagtcttc tcttgtcctt cttttttacc agtaaagaca
    61141 gtgacttgac tagatttcaa gagatctgaa tgggctgtca gtgtgaattt ccctgcttgt
    61201 tcagttgatt tgacaatggc aacaccttta ccattaaatg ctttacgaat ccaagaacca
    61261 tctgcttgcg ccttatagcg ttcacggctg gcttgttctc cgttatctac accgaccagt
    61321 tgaccttggc catgcaattg gaagcgaacc agattattag cagttggaac cacattcccc
    61381 tggctgtcaa caatttcata gtagatgtaa gtcaagtctt ttccatctgc tgcaatcgca
    61441 tggtcttcct taataagacg aactgccgct ggcttaccag cagtcgtaat cttatctcga
    61501 gcaatttcct tgccagattc atcacgagca attgcttcca aggtacctgg ttgataggca
    61561 actttccatt caagataaag ttcattagca tttgcacctt cttggtaagt ccgcccatcg
    61621 ctggtttgtt ttttattgaa agtcttaaga ccaagagatt ttccattcaa gaacaattct
    61681 acactagaag cattcgaata agcacgaact ggaatcttac cttctgagtc agctactttg
    61741 gatgctaatt ctttgttttc ccagttccag tgaggaagaa ggtgtaccat cggtttcttc
    61801 ttaacagaaa cccattggct ttggtagagg tagaagtcat gttttggaat gccggctgta
    61861 tctacgatac caaagtaaga gctcttaaca ggagtttgat tttggttgtg ccatggtgta
    61921 ggttcaccaa tatagtccgt acctgtccag ataaactgtc cagcatagcc agcgttgtca
    61981 cggtcaaaag tccatgaagc ggttgctgtt ttcccccaac caacacgatc attcccatag
    62041 tcagactgtt cataattacg ctcaggtcca ttgctatgtt tcaattcacg ttcagggcga
    62101 tagtaacttc cacgtgtacg ggtagctgaa gatgtttctg atccataaat caaccatttt
    62161 ggatgcttag ctctaagggc tttgtaatta tcttcagaat agttaaatcc aacagcatcg
    62221 agttcatcag caattttctc atgccctccg ctaccattac cgaaacggaa tttatctgct
    62281 cccatggtaa catagcgagt cttatcaaca tccttgataa ccttgaccaa acgtttaaca
    62341 gttgctaaag agtgggcatc accattagct tcacctattt cattaccaat tgaccacatg
    62401 aagatagcag ggttattttt gcctctttcg accatggtac gtaggtcaaa atcagaccat
    62461 ttttcacctt ttcgagcttc tgggtgagtg gcatcttttt caaagaaacg tccatagtca
    62521 taaggtttct tgccaccata ccaagtatca aaggcctctt cctgaacgag taaacctagt
    62581 tctgctgcga tttgcaaggt ttgctcacta gcagggttgt gggttgtacg gatggagtta
    62641 actcccatct ccttcatttg tttgagacgg cgatattctg ctttatagtt ttcttctgct
    62701 ccaagcgccc catggtcgtg gtgcaaggat actccatgga atttaatacg ttcaccattc
    62761 aaagagaaac cttcatttgg agtccagtga tagtaacggt aaccaaacaa atccttctta
    62821 gcatcaacca attgaccgtc acggtaaaca cgcgtaatca attcgtacaa ggcaggtttg
    62881 tcatttaaaa cggtccagag ttttggtctt tcaacttcta aaatcgcatc taggcttgtt
    62941 gattcatgtg cttttaaggt acgactcgct gtacgaacta agcctgttac agcatgacca
    63001 cctcgttcaa cgatttgata ttcggctaca agttcatggt ctttgtcgtc cgtattgacg
    63061 attttgctgg tcacatgagt ttcaaccttg ccatgttgtt gttcttcaag ttttggtgtt
    63121 aaaatagttg tcccattttt ctcaacatgc accttatctg tcacttgtaa agtcacatca
    63181 cgatagatac cacttcctga ataccaacgg ctacttggct gtttgttgac tgcatggaca
    63241 gcaatcacat tctcacgacc atctttatga aggtatttgg tgatatcgta tgagaactgg
    63301 ttataaccat ttggataatg ccccactaac tgaccattga cataaacttg agaatccatg
    63361 tagacgccat caaaagtaag gcgaacattt ttcttgaggt ctttttcatc tagtttgaaa
    63421 gtcttgcgat accaagcttc cccaccgttg agctgtccac cttcattttg tgcaggagat
    63481 tcatgatcga aatcgttaaa gatactccag tcatacggta aatctaattt tttccacgta
    63541 gatacgtctg catcaggttt aatggcttcc ttagaatttg cattgagttt aaagtaccaa
    63601 ttttgattaa aatccacttt cctgtcttca atcatttgat tcacttcttc atttgttaca
    63661 gctttagcat cttccttgag cggtttttct tgacttgaag cttgtgattc tatccttgga
    63721 gctttttctt ccggtttagc agacactttt tcctcttttg gagttacggc ttcatcttct
    63781 ttcttctcag atgcaatagc ctcagttgaa ctaggttcac tttgttctgt cctttcaact
    63841 acatttttag tttccaaagc tttatcagcc ttttcttcta ctatcatttt ttcctcttta
    63901 ggtttctcag cagtatgagt aataagtgtt tcatccgcat aaactacaga ttctccagct
    63961 atatttcctc ctaatagaac tgcacaagtc ccaatcatta ctgagcaagc tcccacagca
    64021 aacttacgaa tgctataaac tcttttccga ttccaatggc ctttccccat aaaaccctcc
    64081 ttatattata tttagtgcag ttagctacta ccaaagccca agtggtatac atggtatgac
    64141 aacctagttt caacaattta cactctgcga aaatccaatt caaacttcgt cagtgtcgcc
    64201 ttgccgtaga tatgatt
//
LOCUS       DAVHKZ010000007        56680 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000007 DAVHKZ010000000
VERSION     DAVHKZ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56680
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.007"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..414
                     /locus_tag="VVO74_000575"
     CDS             <1..414
                     /locus_tag="VVO74_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HEU5694647.1"
                     /translation="ATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPS
                     NSGSGVTPMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLP
                     NTGETQTSMASIGFLGLALAGLLGGLGLKNKKEEN"
     gene            581..1279
                     /locus_tag="VVO74_000576"
     CDS             581..1279
                     /locus_tag="VVO74_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5694648.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            1276..2328
                     /locus_tag="VVO74_000577"
     CDS             1276..2328
                     /locus_tag="VVO74_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU5694649.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            2523..3134
                     /gene="rpsD"
                     /locus_tag="VVO74_000578"
     CDS             2523..3134
                     /gene="rpsD"
                     /locus_tag="VVO74_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU5694650.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            3319..3474
                     /locus_tag="VVO74_000579"
                     /pseudo
     CDS             3319..3474
                     /locus_tag="VVO74_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            3900..4250
                     /locus_tag="VVO74_000580"
     CDS             3900..4250
                     /locus_tag="VVO74_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694651.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALTDDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
     gene            4569..5498
                     /locus_tag="VVO74_000581"
     CDS             4569..5498
                     /locus_tag="VVO74_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU5694652.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            5512..6435
                     /locus_tag="VVO74_000582"
     CDS             5512..6435
                     /locus_tag="VVO74_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU5694653.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            6519..7994
                     /locus_tag="VVO74_000583"
     CDS             6519..7994
                     /locus_tag="VVO74_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU5694654.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            8266..9252
                     /locus_tag="VVO74_000584"
     CDS             8266..9252
                     /locus_tag="VVO74_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU5694655.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            9374..10234
                     /locus_tag="VVO74_000585"
     CDS             9374..10234
                     /locus_tag="VVO74_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEU5694656.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(10306..11370)
                     /locus_tag="VVO74_000586"
     CDS             complement(10306..11370)
                     /locus_tag="VVO74_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694657.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIANLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLKSPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(11433..12344)
                     /locus_tag="VVO74_000587"
     CDS             complement(11433..12344)
                     /locus_tag="VVO74_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEU5694658.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            complement(12337..12930)
                     /locus_tag="VVO74_000588"
     CDS             complement(12337..12930)
                     /locus_tag="VVO74_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU5694659.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYATRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            complement(12917..13243)
                     /locus_tag="VVO74_000589"
     CDS             complement(12917..13243)
                     /locus_tag="VVO74_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU5694660.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            complement(13382..14548)
                     /locus_tag="VVO74_000590"
     CDS             complement(13382..14548)
                     /locus_tag="VVO74_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEU5694661.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            14606..15763
                     /locus_tag="VVO74_000591"
     CDS             14606..15763
                     /locus_tag="VVO74_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU5694662.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKEDIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVINNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML"
     gene            15805..17655
                     /locus_tag="VVO74_000592"
     CDS             15805..17655
                     /locus_tag="VVO74_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU5694663.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(17741..17998)
                     /locus_tag="VVO74_000593"
     CDS             complement(17741..17998)
                     /locus_tag="VVO74_000593"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694664.1"
                     /translation="MKIKEQTRKLAAGCSKHCFKIVDGTDEVSSKHCFKVVDGTDEVS
                     SKHCFEVADRTDEVSSKHCFKVVDGTDEVSNHIRQGDVDVI"
     gene            complement(18048..18680)
                     /locus_tag="VVO74_000594"
     CDS             complement(18048..18680)
                     /locus_tag="VVO74_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU5694665.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(18702..19574)
                     /gene="sdaAA"
                     /locus_tag="VVO74_000595"
     CDS             complement(18702..19574)
                     /gene="sdaAA"
                     /locus_tag="VVO74_000595"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU5694666.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(19583..20254)
                     /gene="sdaAB"
                     /locus_tag="VVO74_000596"
     CDS             complement(19583..20254)
                     /gene="sdaAB"
                     /locus_tag="VVO74_000596"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU5694667.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            20496..21083
                     /locus_tag="VVO74_000597"
     CDS             20496..21083
                     /locus_tag="VVO74_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU5694668.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQKLVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(21135..21455)
                     /locus_tag="VVO74_000598"
     CDS             complement(21135..21455)
                     /locus_tag="VVO74_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU5694669.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVPIGICRDDAKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            21879..22166
                     /locus_tag="VVO74_000599"
     CDS             21879..22166
                     /locus_tag="VVO74_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU5694670.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            22218..24326
                     /locus_tag="VVO74_000600"
     CDS             22218..24326
                     /locus_tag="VVO74_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU5694671.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            24323..24964
                     /locus_tag="VVO74_000601"
     CDS             24323..24964
                     /locus_tag="VVO74_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694672.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            25171..25977
                     /locus_tag="VVO74_000602"
     CDS             25171..25977
                     /locus_tag="VVO74_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU5694673.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            25943..26413
                     /locus_tag="VVO74_000603"
     CDS             25943..26413
                     /locus_tag="VVO74_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEU5694674.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQIGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(26599..27462)
                     /locus_tag="VVO74_000604"
     CDS             complement(26599..27462)
                     /locus_tag="VVO74_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5694675.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            27928..28266
                     /locus_tag="VVO74_000605"
     CDS             27928..28266
                     /locus_tag="VVO74_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEU5694676.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            28244..28739
                     /locus_tag="VVO74_000606"
                     /pseudo
     CDS             28244..28739
                     /locus_tag="VVO74_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424410.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            28893..29105
                     /locus_tag="VVO74_000607"
     CDS             28893..29105
                     /locus_tag="VVO74_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694677.1"
                     /translation="MLIVLISVIVALLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQTK"
     gene            29585..29830
                     /locus_tag="VVO74_000608"
     CDS             29585..29830
                     /locus_tag="VVO74_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694678.1"
                     /translation="MGIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSASPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            29987..31045
                     /locus_tag="VVO74_000609"
     CDS             29987..31045
                     /locus_tag="VVO74_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694679.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPFSVFTFMFSYILLFVQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            31360..32337
                     /locus_tag="VVO74_000610"
     CDS             31360..32337
                     /locus_tag="VVO74_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694680.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLISFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKQFKKINNPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            32714..33088
                     /locus_tag="VVO74_000611"
     CDS             32714..33088
                     /locus_tag="VVO74_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEU5694681.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            33296..34198
                     /locus_tag="VVO74_000612"
     CDS             33296..34198
                     /locus_tag="VVO74_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694682.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHLLVSNLQLNLEIPLDFVVSTSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEMSISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            34254..34586
                     /locus_tag="VVO74_000613"
     CDS             34254..34586
                     /locus_tag="VVO74_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU5694683.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            34583..35311
                     /locus_tag="VVO74_000614"
     CDS             34583..35311
                     /locus_tag="VVO74_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694684.1"
                     /translation="MNNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSSWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            36444..36683
                     /locus_tag="VVO74_000615"
     CDS             36444..36683
                     /locus_tag="VVO74_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694685.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            36668..36946
                     /locus_tag="VVO74_000616"
     CDS             36668..36946
                     /locus_tag="VVO74_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694686.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVARDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKSVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            37235..39061
                     /gene="pspA"
                     /locus_tag="VVO74_000617"
     CDS             37235..39061
                     /gene="pspA"
                     /locus_tag="VVO74_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HEU5694687.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVAKQSQAER
                     DYDAAMKKSEAAKKEYEEAKKDLEEAKAAQKKYEDDQKKTEEKAKLVQKADEERQKAN
                     VAVQKAYLKLREAQEQLNKSPNNKKNAAQQKLKDALAHIDEVTLKQKEAEANFNKEQA
                     KVVPEADKLAETKKKAEQAEKKEPELAKKVAEAKAKAEEAEKKAVEAKQKVDAEKYAL
                     EAKIAELEYEVQGLEKELKEIDESDSEDYIKEGLRAPLQSKLDAKKAKLSKLEELSDK
                     IDELDAEIAKLEKDVEDFKNSDGEQAEQYLVAAKKDLDAKKAELENTEADLKKAVDEP
                     ETPAPAPKPAPAPAPTPEAPAPAPKPAPAPKPAPAPAPKPAPAPKPAPAPKPETPKTG
                     WKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGAMATGWAKVNGLWYYLNSNGAMA
                     TGWLQYNDSWYYLNTNGAMATGWLEYNGSWYYLNANGAMATGWLEYNGSWYYLNSNGA
                     MATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEAS
                     GAMKANQWFKVSDKWYYVNGLGALAVNTTVDGYTVNENGEWV"
     gene            39462..40583
                     /gene="mnmA"
                     /locus_tag="VVO74_000618"
     CDS             39462..40583
                     /gene="mnmA"
                     /locus_tag="VVO74_000618"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU5694688.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLKKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            40724..41179
                     /locus_tag="VVO74_000619"
     CDS             40724..41179
                     /locus_tag="VVO74_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU5694689.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYIIGGA
                     IQVNEKTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            41189..43102
                     /gene="mnmG"
                     /locus_tag="VVO74_000620"
     CDS             41189..43102
                     /gene="mnmG"
                     /locus_tag="VVO74_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU5694690.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWASFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(43297..44976)
                     /locus_tag="VVO74_000621"
     CDS             complement(43297..44976)
                     /locus_tag="VVO74_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU5694691.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(44978..45211)
                     /locus_tag="VVO74_000622"
     CDS             complement(44978..45211)
                     /locus_tag="VVO74_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU5694692.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            complement(46029..46181)
                     /gene="cibB"
                     /locus_tag="VVO74_000623"
     CDS             complement(46029..46181)
                     /gene="cibB"
                     /locus_tag="VVO74_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU5694693.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(46183..46368)
                     /gene="cibA"
                     /locus_tag="VVO74_000624"
     CDS             complement(46183..46368)
                     /gene="cibA"
                     /locus_tag="VVO74_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEU5694694.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            46546..47229
                     /gene="tsaB"
                     /locus_tag="VVO74_000625"
     CDS             46546..47229
                     /gene="tsaB"
                     /locus_tag="VVO74_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU5694695.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            47226..47663
                     /gene="rimI"
                     /locus_tag="VVO74_000626"
     CDS             47226..47663
                     /gene="rimI"
                     /locus_tag="VVO74_000626"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU5694696.1"
                     /translation="MIEIKRIQQQPALAQDIYAVMAAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLTVQETLFEAEVLQIAVKGACQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            47653..48663
                     /gene="tsaD"
                     /locus_tag="VVO74_000627"
     CDS             47653..48663
                     /gene="tsaD"
                     /locus_tag="VVO74_000627"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU5694697.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(48703..50009)
                     /locus_tag="VVO74_000628"
                     /pseudo
     CDS             complement(48703..50009)
                     /locus_tag="VVO74_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(50285..50636)
                     /locus_tag="VVO74_000629"
                     /pseudo
     CDS             complement(50285..50636)
                     /locus_tag="VVO74_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(50743..51036)
                     /locus_tag="VVO74_000630"
                     /pseudo
     CDS             complement(50743..51036)
                     /locus_tag="VVO74_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            51279..52485
                     /locus_tag="VVO74_000631"
                     /pseudo
     CDS             51279..52485
                     /locus_tag="VVO74_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            52478..53274
                     /locus_tag="VVO74_000632"
                     /pseudo
     CDS             52478..53274
                     /locus_tag="VVO74_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            53361..54977
                     /locus_tag="VVO74_000633"
     CDS             53361..54977
                     /locus_tag="VVO74_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694698.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRIATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            54997..55842
                     /locus_tag="VVO74_000634"
                     /pseudo
     CDS             54997..55842
                     /locus_tag="VVO74_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            55871..56197
                     /locus_tag="VVO74_000635"
     CDS             55871..56197
                     /locus_tag="VVO74_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694699.1"
                     /translation="MENTLLNITGSFDMETRNLISYSLTDIFETDKIRIELLGEIYYK
                     NIKLELHEFAGLYKIYGISLIKNITGMFLIIIFDTKTKELKIFQDITTSYFNLYYTVY
                     GGVFYI"
     gene            56217..>56680
                     /locus_tag="VVO74_000636"
     CDS             56217..>56680
                     /locus_tag="VVO74_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
                     /protein_id="HEU5694700.1"
                     /translation="MKLSHVPVTLNNKKIQEFMRNGFILDSNTLVTEINKLEYFSYIS
                     VNNTIRICGIDYNDSNNFTKEQVLKNWDSMLRESILRVYSEAGEANITLSSGFDSNYI
                     LYTLANYTNSSINAFCIGGEKGINEIPEVTKIAKFYGINLLVDTVMSQDLES"
BASE COUNT        17661 a         9562 c        11932 g        17525 t
ORIGIN      
        1 gctacagtca atgtctatgg taacaaagac ggtaaaccag acttggacaa catcgtagca
       61 actaaaaaag tcactattaa gataaatgtt aaagaaacat cagacacagc aaatggttca
      121 ttatcacctt ctaactctgg ttctggcgtg actccgatga atcacaatca tgctacaggt
      181 actacagata gcatgcctgc tgacaccatg acaagttcta ccaacacgat ggcaggtgaa
      241 aatatggctg cttctgctaa caagatgtct gatacgatga tgtcagagga taaagctatg
      301 ctaccaaata ctggtgagac tcaaacatca atggcaagta ttggtttcct tgggcttgcg
      361 cttgcaggtt tactcggtgg tctaggtttg aaaaacaaaa aagaagaaaa ctaatcagct
      421 aaggaaataa atgatggata gtgggctgac taagattagt ttaacaactc aatcagcaat
      481 caggactttc tttcaatagc agattaaaat catcgtaaaa caataaaaat agtgttatac
      541 ttaaagcagt atagcactgt ttttatcaaa ggagagacag atgggaaaga caattttact
      601 cgttgacgac gaggtagaaa tcacagatat tcatcagaga tacttaattc aggcaggtta
      661 tcaggtcttg gtagcccatg atggactgga agcgctagag ctgttcaaga aaaaaccgat
      721 tgatttgatt atcacagatg tcatgatgcc tcggatggat ggttatgatt taatcagtga
      781 ggttcaatac ttatcaccag agcagccttt cctatttatt actgctaaga ccagtgagca
      841 ggacaagatt tacggcctga gcttgggagc agatgatttt attgctaagc cttttagccc
      901 acgtgagcta gttttgcgtg tccacaatat tttgcgccgc cttcatcgtg ggggcgaaac
      961 agagctgatt tcccttggca atctaaaaat gaatcatagt agtcatgaag ttcaaatagg
     1021 agaagaaatg ctggatttaa ctgttaaatc atttgaattg ctgtggattt tagctagcaa
     1081 tccagagcga gttttctcca agacagacct ctatgaaaag atctggaaag aagactacgt
     1141 ggatgacacc aataccttga atgtgcatat ccatgctctt cgacaggagc tggcaaaata
     1201 tagtagtgac caaacgccca ctattaagac agtttggggg ttgggatata agatagagaa
     1261 accgagagga caaacatgaa actaaaaagt tatattttgg ttggatatat tatttcaacc
     1321 ctcttaacca ttttggttgt tttttgggct gttcaaaaaa tgctgattgc gaaaggcgag
     1381 atttactttt tgcttgggat gaccatcgtt gccagccttg tcggtgctgg gattagtctc
     1441 tttctcctat tgccagtctt tacgtcgttg ggcaaactca aggagcatgc caagcgggta
     1501 gcggccaagg attttccttc aaatttggag gttcaaggtc ctgtagaatt tcagcaatta
     1561 gggcaaactt ttaatgagat gtcccatgat ttgcaggtaa gctttgattc cttggaagaa
     1621 agcgaacgag aaaagggctt gatgattgct cagttgtcgc atgatattaa gactcctatc
     1681 acttcgatcc aagcgacggt agaagggatt ttggatggga ttatcaagga gtcggagcaa
     1741 gctcattatc tagcaaccat tggacgccag acggagaggc tcaataaact ggttgaggag
     1801 ttgaattttt tgaccctaaa cacagctaga aatcaggtgg aaactaccag taaagacagt
     1861 atttttctgg acaagctctt aattgagtgc atgagtgaat ttcagttttt gattgagcag
     1921 gagagaagag atgtccactt gcaggtaatc ccagagtctg cccggattga gggagattat
     1981 gctaagcttt ctcgtatctt ggtgaatctg gtcgataacg cttttaaata ttctgctcca
     2041 ggaaccaagc tggaagtggt ggctaagctg gagaagggcc agctttcaat cagtgtgacc
     2101 gatgaagggc agggcattgc cccagaggat ttggaaaata ttttcaaacg cctttatcgt
     2161 gtcgaaactt cgcgtaacat gaagacaggt ggtcatggat taggacttgc gattgcgcgt
     2221 gaattggccc atcaattggg tggggaaatc acagtcagca gccagtacgg tctaggaagt
     2281 acctttactc tcgttctcaa cctctctggt agtgaaaata aagcctaaaa cccctttaca
     2341 aatccagcta ttcatggtag aatgaatttt gtgtgaaata tcagcaggaa agcatgaagc
     2401 tcgtcaacag gtgtcttatg ataagtaacc ttggctgttt aggcgaaggg catctgcacg
     2461 aatcagggct ttctaagtga ctatttccac cgaaatatta tttatatcag gaggacattc
     2521 atatgtcacg ttatacagga ccatcttgga aacaagctcg tcgccttggc ctttcactta
     2581 caggtacagg taaagaattg gcacgtcgta actacgtacc aggacaacac ggaccaaaca
     2641 accgttctaa attgtcagaa tacggtttgc aattggctga aaaacaaaaa cttcgtttca
     2701 cttacggtgt aggtgaaaaa caattccgta acttgtttgt acaagctaca aaaatcaaag
     2761 gcggaatcct aggtttcaac tttatgcttc ttttggaacg tcgtttggat aacgttgttt
     2821 accgtcttgg tctcgcgact actcgtcgtc aagctcgtca atttgtaaac cacggtcaca
     2881 tccttgttga cgggaaacgc gttgatatcc catcataccg cgtaactcca ggtcaagtga
     2941 tctcagttcg tgaaaaatca ttgaaagttc cagcaatcct tgaagcagta gaagctactc
     3001 ttggacgtcc agcattcgta tcattcgacg ctgaaaaatt ggaaggttca ttgactcgct
     3061 tgccagaacg cgacgaaatc aacccagaaa tcaacgaagc acttgtcgtt gaattctaca
     3121 acaaaatgtt gtaatatttt attaaataag ataggctgta aagccttgaa actaagcact
     3181 ttgggacgtt ctcccttagt gcttttttga tttctcttag tatccagcta taatcgttta
     3241 gacataacta gaccgatata gtccaaagtg atatagtaaa atgaaccaaa aatagtacac
     3301 aatgtggtat aatcttttat ggaatattca atagattttc gtaaaaaagt tctctcttat
     3361 tgtgagcgaa caggtagtat aacagaagca tcacacgttt tccaaatctc acgtaatacc
     3421 atttatggct ggttaaagct aaaagagaaa acaggagagc taaaccacca agtatagtgt
     3481 attgaatcta taacagtaca ccttggctgc taaaatattt ctataaatta atttgacttt
     3541 cctgatagag ttgttcacat cttatttcaa atcactataa aagctctata atctctttat
     3601 aagatttgcc catcagacga aatataatgg attgaaacta gaatagtaca cctctacttc
     3661 taaaacattg ttagaaatcg atttgactgt cctgatcgat ttgtcctgtt cttgtttcat
     3721 tttactatag aacgatttga aggcgtttat gatatttagc tgtacgagag tcttttaaaa
     3781 gtgttttgat ggtttggatt tcttctttag ttgatttcat atcactgtta tgtaatgctt
     3841 tttgatttta gtctagtatt agtaagcaga ctcaaacctt agaaaatctt ttgagatcat
     3901 tgacaggtgt atcgaatcct accacagatt cagcacgtct ggttttggca gaggctaaga
     3961 aagctcttac agatgatagt ttgacagagc aaggtttacg tgatatcttg caaacagtca
     4021 aagatgccat tgcttcccta gagtccatta aggaaagcca gtcagcaact aaggatggag
     4081 gacaaacagc gggcaaagaa acagcagata aggatgtcct tgaaaactct caagaagaac
     4141 ttcaaaaagc agttttgttc ttggcagatg aaaaaggctc tgagcatact gaagcagagt
     4201 tgattgataa tcttaaagag gttattgcta agttgaaagc aaacgcctaa taacatatta
     4261 aaaatctcca gattaggaac tatcgctgag ttccctagtc tggagatttt tcagtatacc
     4321 ccgttgttgg atgcttataa cagagtgacg ccatcactgg gctaatagag ataaaataaa
     4381 caattgattt aggacatttg tttgatagtg gtgataaagt tttaaatctg ctacataatt
     4441 tgtggaattt tttctataat taggagttta acctaacctg caaataggag tatactaata
     4501 atgtaatcgt tatcaaaagt ctaaaaaaga atttttagat ggatatcaaa ataaaaaggg
     4561 aggaaattat gaaaaagttt tcaaaaacat tgagagacaa ctggatcttt ctcttgatgg
     4621 ttttgccagg ggcactctgg ttgattctat tcttttacat tccagtattt gggaacgtgg
     4681 ttgccttcaa agactaccac atgaccagta atggtttcat agatagtatc ataaatagta
     4741 aatgggtcgg actcgataat ttcagattct tatttagttc aagagacgcc tttattatca
     4801 cacgaaatac tgtcctctac aatcttggct ttatctttct aggtttagtt gtatctgtag
     4861 ggattgccat tatcctcagc gagctccgtt ctaagagaat ggtgaagatt ttccaaactt
     4921 ctatgttgtt cccttacttc ttgtcttggg ttatcatcag tttctttaca gatgccttcc
     4981 taaatattga taaaggggtg ttcaatcatc tattggaaag tcttggtctc aaagaagtca
     5041 atttctacgc tgacctgggc atctggccct atctcctact tttcctaggt atttggaaag
     5101 gttttggata tagcagtgtc atgtactatg cgacgatcat gggaattgat ccaacctact
     5161 acgaagcagc gacagtggac ggagctagca agtggcaacg tattcgcaac gtaaccattc
     5221 ctcagttgac tccgcttgta actgtattga ccatccttgc agtcggaaat atcttccgcg
     5281 cagacttcgg tctcttctat caaatcccac acaatgctgg tcagctttac aatgtaacca
     5341 acgttttgga cgtatatgtt tttaatggtt tgactcagac agcagatatc ggtatggctg
     5401 cagcagccgg tctttaccaa tccgttgttg gtttgattct ggttatccta tcaaacttgc
     5461 ttgcaagacg agtcgatcca aactcagctt tgttctagaa aggaggagaa tatggcaaaa
     5521 aagaaaatta aaaaagaaaa aattgataat gtcggcattc actccttcag taagaaagca
     5581 gatatcttct tcagtatcat ttcgggtttg attgccctct cttgtatcct accttttgta
     5641 ttcgttatca ttatttcagt gacagacgag aaaagcctcc tccaatacgg ctatagcttc
     5701 ttcccatccc aatttggctt agacggtttt gagtttttgg cacagtttaa ggataaaatc
     5761 ctacaagccc tcttcatctc tgtctttgta accgtagttg ggacattgac aaatgtcttt
     5821 atcacaacaa cctatgccta cgctatttca cggacaacct ttaagtatcg cagatttttt
     5881 accatcttcg tccttctcag tatgttgttc aacgctggtt tggtaccagg ttatatcatg
     5941 gtgacccgtg tacttcagct tggtgacact gtttgggcct tgattgttcc aatgcttctc
     6001 tcaccattca atatcatctt gatgcgttcc ttcttcaaga agaccattcc agaagccatt
     6061 ctcgaatcgg ctcgtatcga tggtgccagt gaggcccgga ttttcttcca aatctgtttg
     6121 ccattgtcac taccaggtat cgcaaccatc acgcttttga cagctcttgg tttctggaat
     6181 gactggttca acgcccttct ttacatcaag agtgacaact tgtatccatt gcaatatttg
     6241 ctcatgcaaa tccaacaaaa tatggactac attgccaaag cggtcggctt gactggtcaa
     6301 ctgggagttg ctctaccgaa agaaacaggt cgtatggcca tggttgtggt agcaaccctt
     6361 ccaatcgcaa ttttgtatcc attcttccaa cgctactttg taaaaggttt gactatcggt
     6421 ggtgtgaaag aatagcactt gtttccaaac ttcccttgcg tgaagttaag atcattacat
     6481 tgtttataag tttaaaaata aaaaaaggag tttttatcat gaaaaactgg aaaaaatatg
     6541 cttttgcatc tgctagtgta gtcgctttgg ctgcaggtct tgctgcttgt ggaaatttga
     6601 caggtaacag caaaaaagct gctgattcag gtgacaaacc tgttatcaaa atgtaccaaa
     6661 tcggtgacaa accagataac ttggatgaat tgttagcaaa tgccaacaaa atcatcgaag
     6721 aaaaagttgg tgccaaattg gatatccaat accttggctg gggtgactat ggtaagaaaa
     6781 tgtcagttat cacatcatct ggtgaaaact atgatatcgc ctttgcagat aactatattg
     6841 taaatgctca aaaaggtgct tatgctgact tgacagaatt gtacaaaaaa gaaggtaaag
     6901 acctttacaa ggcacttgat ccagcttata tcaagggtaa tactgtaaat ggtaagattt
     6961 acgctgtacc agttgcagcc aacgtagcat catctcaaaa ctttgccttc aacggaactc
     7021 tccttgccaa atatggtatc gatatttcag gtgttacttc ttacgaaact cttgagccag
     7081 tcttgaaaca aatcaaagaa aaagctccag acgtagtacc atttgctatt ggtaaagttt
     7141 tcatcccatc tgataacttt gactacccag tagcaaacgg gcttccattc gttattgacc
     7201 ttgaaggcga tactactaaa gttgtaaacc gttacgaagt gcctcgtttc aaagaacact
     7261 tgaagactct tcacaaattc tatgaagctg gctacattcc aaaagacgtc gcaacaagtg
     7321 acacttcatt tgaccttcaa caagatactt ggttcgttcg tgaagaaaca gtaggaccag
     7381 ctgactacgg taacagcttg ctttcacgtg ttgccaacaa agatatccaa atcaaaccaa
     7441 tcactaactt catcaagaaa aaccaaacaa cacaagttgc taactttgtc atctcaaaca
     7501 actctaagaa caaagaaaaa tcaatggaaa tcttgaacct cttgaatacg aacccagaac
     7561 ttttgaacgg tcttgtttac ggtccagaag gcaagaactg ggaaaaaatt gaaggtaaag
     7621 aaaaccgtgt tcgcgttctt gatggctaca aaggaaacac tcacatgggt ggatggaaca
     7681 ctggtaacaa ctggatcctt tacatcaacg aaaacgttac agaccaacaa atcgaaaatt
     7741 ctaagaaaga attggcagaa gctaaagaat ctccagcgct tggatttatc ttcaatactg
     7801 acaatgtgaa atctgaaatc tcagctattg ctaacacaat gcaacaattt gatacagcta
     7861 tcaacactgg tactgtagac ccagataaag cgattccaga attgatggaa aaattgaaat
     7921 ctgaaggtgc ctacgaaaaa gtattgaacg aaatgcaaaa acaatacgat gaattcttga
     7981 aaaacaaaaa ataatcagct aaattgattt cgtgtattca ttcctaactc ctaaaataag
     8041 aatcaccgct ttcctcaggt tggtctgggg agggcagtgg tttttttggc acaaggatat
     8101 agatatccat gttttctctt gtccttattt taaccattca ggaaatttcg agaaccctct
     8161 acaatttcca gtcaaataaa ttgcattcgt tttctcaagc aggtatacta gtgtagataa
     8221 ataaaaaatt tagaaaattt aagaatagaa aagagaacaa atcttatggc aaaagatatt
     8281 cgtgtcttac tttactacct ttatactcca attgaaaatg cagagcaatt tgctgcagac
     8341 cacttggctt tctgtaaatc aatcggcctt aaaggccgta tcctagtcgc tgacgaggga
     8401 attaacggaa cagtttcagg tgactatgaa acaactcaaa aatacatgga ctacgttcac
     8461 agccttccag gaatggaaga actctggttc aagattgacg aagaaaatga acaagccttc
     8521 aagaagatgt ttgttcgcta caagaaagaa attgtccacc ttggtttgga agacaacgac
     8581 tttgacaatg acatcaaccc acttgaaaca acaggtgctt acttgtctcc aaaagagttc
     8641 aaagaagcgc ttcttgataa agataccgtt gtccttgaca cacgtaacga ttatgagtac
     8701 gacctaggac atttccgtgg ggctattcgc ccagatattc gcaacttccg tgagttacca
     8761 caatgggtcc gtgataacaa ggaaaaattc atggacaagc gtgtcgtggt ttactgtaca
     8821 ggtggcgttc gctgtgagaa attctcaggc tggatggtcc gtgaaggcta caaagatgtc
     8881 ggccaattgc acggaggaat cgcaacttac ggtaaagacc cagaagttca aggtgagctt
     8941 tgggatggga aaatgtacgt ctttgacgag cgtattgccg ttgatgtcaa ccatgtcaac
     9001 ccaaccatcg tagggaaaga ctggtttgat ggaacaccat gtgaacgtta tgtcaactgt
     9061 ggaaatccct tctgtaaccg tcgtatcttg acatcagaag aaaatgaaga caagtacctt
     9121 cgtggatgct cacacgagtg ccgtgttcac ccacgtaacc gctatgtttc aaaaaatgaa
     9181 ttgacacaag ctgaagtgat tgagcgccta gccgctatcg gtgaaagctt ggatcaggca
     9241 gctactgtat aagatcaaac agtcctcagg ggctgttttt ctatgctttg tactcaaaaa
     9301 tctaaagttt gtttttgtat ctttcaggaa aataaggtat actgtatgta aacgatttca
     9361 aaggagtcca gttatggcaa aaacattttt tattccaaat aaacagagca ttttaggaga
     9421 acaagagatt ttgaatgcca agtcgatctt ggccttgcta gacggtttgg agtcacatag
     9481 ctatgatgta gtctatcttc gtcagcctct taatcgtctc gagtatattg agtgtgcgat
     9541 agtggggcaa tcacaatttc tctttaaggt cagttatgct gatggtcaaa aggcttaccg
     9601 tgtcgatctt cctgacctac taacaaagac agactggcag attatcaagt catttttaga
     9661 tgctttgctt gcttatacag ggactgatat tgaagggcta gatggttttg attttgaagc
     9721 ttatttccaa gcaagtattc aagcctatct agcagaccct gtagctcgtt ttacgatttg
     9781 ccaaggaatt tttaatccta ttttctttag tcgtgagaac ttgaaaagct ttttagaggc
     9841 agatggcttg gctcagtttg aagcgcgtgt gcgtgcggtt caagagacag atgcctactt
     9901 tgcaagagtt tccttctatc aggatggaga aggaaaagtg catggcgttt accatttagc
     9961 tcaaggagtc aagacagttt taccgagaga accgtttgtt cctgcagcct atattgagca
    10021 attggtggat aaggaagtcc agtgggagat tgacttggtt caaatcacag gagacggctc
    10081 taaaccagaa gactatgaat ccatagctcg cttggactat gcaaaattct tagaggtatt
    10141 acccccatct ttttaccacc aactagacgc caatcaaata gaagtgcaac ccatattaga
    10201 caaagatttt aaaacattag cacaagaaaa gtaaagcaga agcaggtcaa tcgacttgct
    10261 tttttgacat agaaaaaatc ctgccaagga tgacaggatt gaattttaaa gaaaggccaa
    10321 gatacgaaga taatctccaa tcagtgccac ttcagctaca aagaagagga ggataataac
    10381 tccgttcaca aggacagaca agaataattg atagaaggag tcggtttcac ttgcttgact
    10441 tggtcttgta atgatatgga gactggcaag cagaatgatt ccaatgctaa tcacacacaa
    10501 gagagctgta aatcgtaggc tatcaaagaa agcaaagaaa ctagcaatag cagtgaggaa
    10561 gattggaatt gccaagagtt gactatattg ttggagaacc ttgtctagcg tccagtcctt
    10621 ttcctggtgg ataaatcgtc tcacaacgaa actacccaag aggaatgaaa agaagaagag
    10681 tgttgtcgct actaggatag agatgataga aaaaagagtt aaaggagcta gctgctcagg
    10741 gaagcgactg ttaatgcttg ctatatgtcc atagtaagca tgtttgatgt gatagatact
    10801 aaagaaaaag gaagatgcag aaaacagaat gagcaagaga aaggctgtgt aactgtgtgt
    10861 gatacttgtt tccaacttac ttgtaggaga tttgatcgct tctactagcc aagaccaaaa
    10921 atcaagcact tgctctttcc atttatccct agattttgga gcttggtcgg ggatataagg
    10981 actttttaaa gatttactga taagaagtgg ctctttcgtg gttgcttttt gctgaggaag
    11041 agcttcttgg ctctcttcag ctatagtgac tttttctgtt tctttagaaa ggtctggctc
    11101 ttcttcagta gaattagatg ccttcttttc ttctatttct gttctcgctt caccgccttc
    11161 aggagtttca attttctctt cttgctggct ttccagttcg acttcagctt gagagacttc
    11221 ctcctctact tgagtatttt ttccaattgg tgtatcgaga ttggctatcg tttcttcagc
    11281 cttgtctgca acctcttgag cttgctcttc aggcttgttc ttgcttgttg tttttacaaa
    11341 atcattactt tcaaaccatt cttgtttcat ggtagaacct cctttttagt tagataaata
    11401 tgtttccata gtagcaaatg taagcgtttt tgtcaacgtc tgcttggtgt ggatattaga
    11461 tcaatattat catcagatct cgcaatgagt tgatccttga catcggtttt ttcagttttg
    11521 taagggttgc ttaattccgt acctcttgat tcaggctttt ctcttgtgaa ttggaagata
    11581 gaaccatagt tgcttgagat gtcccagtta attcgttggc tttctttctg gtctaggatg
    11641 attctgagat aatctttggc agtcagttca accttgccat ggacttggat attttcagcg
    11701 tggaagtgat tctctgttga ctctagctga ctatctgtaa gaactgtatc aaagatatta
    11761 acgatattgg gcgttgtgag tttactgttt ttgatacgac ttccttcaat tcggaggata
    11821 tagctgtttg tattgagggt cgcattttca aggctagcat ttatgatggt ggtttgtccg
    11881 cgattggctg agatgttgat cccttttaga gttctccctt ttggtagtcg gagaataact
    11941 tcttcaaaac gactagagta gctacttgcg atatgaagaa tcccaccaat tccagaagag
    12001 agaaacggag tttcagacag tttcttatca gtgagactca gagttctatc gttctgattg
    12061 gtgataagat catggtgagc agaaagagat ggatggtaag aaatgtggat ttgatcatcg
    12121 aaagagtctg tgatggtgag cgtgtgttgg tggagagtaa tttctaggtt ttcgacttcc
    12181 ttgccaaagg ttagcttttc cgtacggcta tcatagacag gttctttgga catggaaagt
    12241 aggctcttaa tcccgtcaga ttggatacct acaaaaagca ggataaagcc gataacggta
    12301 gtcaccacac caaagatgag aaatcctttt gtccatttac gcatgctgat tacctctctt
    12361 tcctttttta agaacaaatt gtaccagacg aacaatgagt agaccgaaga agcgagttgc
    12421 ataggaaatg ccaagtaaaa ctagcgaaga agcaccgata gccagtaaac cagaaccaaa
    12481 aatcaagata aaggctgatt tggcttgggc gaggacagtg aaactttcaa ctaaaaatag
    12541 gaatccgccg atgataccca gtatggaaac tgcaaagaaa gccagaatga cagtcaaagc
    12601 ggctacaaga attgcgaaca gggtcacgag gatggcgatt cccagaggaa tgccgatagg
    12661 tgctgcaagg agggctaaca aggcgatatg taaaatttgt cggttatttt tttgagcggg
    12721 tgcttcattg atttttttat cgagaagatt ggatagaact tcgtgggccg cttctttggg
    12781 agttcccaaa ctagcgatga gttcttcttc tccttcgact ccagcatcgt caaagagctc
    12841 tctgaaatag tccatggctt cgatacggtc agcttcaggt agtttcttga gatagagttc
    12901 tagctgagtc aggtattcag ttcttgtcat ggcggatact cccttctatg atgccattga
    12961 tggtgtctgt atagagtgcc cattcatctt ttagggtcaa gagctgctct ataccaccgt
    13021 ttgtcaagga gtagtatttg cgcatgcgac cttggaactc tctagaatag gttgtcagaa
    13081 agctattgcc ttccaatttt ttgagaatgg gatagagtgt ggattctttg atattagcga
    13141 tcagcttaat ggtttggcta atctcataac cataagaatc accctgctcc agtacagcca
    13201 agatgagaaa ttcaatcaag gcagaggatg ttggaaagta catgggaaac ctccttttct
    13261 aatgtgtaag atttttatat ataatttttc tacacataca ttgtacatct aaaagaaagc
    13321 cctgtcaaga gaaatgtgta aaatttttat atataaaaaa cttctagcta aaactagaag
    13381 tttaaaggat cttatccgct ctgtccactg taaagagggc cacagtcatc aggatatcga
    13441 tgagcaagag ggcagctaca gatggtaccc aagagtggaa caggtcaaaa ctgtaaccaa
    13501 agagggttgg cccaaaggct gctaggatat agcctcctgt ttgagatagg ccggacaatt
    13561 gggctgtctt ttcaggggcg cttgtcttga gtgaaaagtt gaccatgaga taagggaaga
    13621 gggcactggt tgcggttccg atgaggagat ggatggcaag ccagtaaatg aaattattga
    13681 ttgggaaaaa gagcatggaa atgccgacca caccagctag tgaaaccaga gtgagcatga
    13741 gctgacggtt gcgagtagat aaactggttg tcaggcttgg gatggtcatt gaaaaaggaa
    13801 tgctaatcag agataagata gaagtcagca agccagcttc gtgactggat agacctgcat
    13861 ggatagacat ggtaggtaac caggtcatga cggtgtaaaa gatcaaggat tgaaaacctg
    13921 aaaagataat aattgcccaa acctgtttat tacgcatgac ctttatttga cttttttgtt
    13981 tggtttgtgg agctagtcta tgattatagc ggtgatttgg gagccagacc aaaaaagttg
    14041 ctagacagag taacgtgagg agaaggataa gtcctttcca agaactggct tgtgtaatgg
    14101 gcacagctag ataggaagcc agagccgttg caatccccat agacgttaca tataaggtgg
    14161 tcagaaaacc aattttcttt ggttgattgg cttggataag actaggaagc aggacattga
    14221 tgactgcgac acttgcccca accatcaagg ttcctagata gagcaggggc agattgatta
    14281 gtcgaataag tgagccgatg gtcaagaaga agaggctgta ggtgaagaga tgctccaagc
    14341 cgattttctg agccagttgg gtagaaaatg gtgaaaagag ggtaaacata aggagaggca
    14401 ggctggtcaa gacaccaagc gaactaactt ctacctccag accttgcgaa atatttccca
    14461 aaataatggg taaaacagta aaaggagttc gcaaggaaac accaatcagg ataatacctg
    14521 gaacaaaaaa gagtgattgc tttttcatat aatacctctt ctagctgatt ttaataacag
    14581 cttattttaa ggctttttca ctataatgtc aagtaaggtt tctggctttc aagataaaaa
    14641 tgggaaagtc ttgaaaatta tgatagaatg gtggaaggaa aaattcagga gagtagtagt
    14701 gactcaaaat gttgaaagtc ttctcgtatc cattgtaatc agtgcataca atgaagaaaa
    14761 atatctgcct ggtctaattg aagacttaaa aaatcaaacc tatcctaaag aggatattga
    14821 aattctattt ataaatgcta tgtccacaga tgggaccaca gctatcattc agcaatttat
    14881 aaaggaagat acagagttta actcaattag attgtataac aatcctaaga aaaatcaagc
    14941 tagtggtttt aacctgggag ttaaacattc tgtaggggac cttattttaa aaattgatgc
    15001 tcattcaaaa gttactgaga gttttgtaat taacaatgtg gctattattc aacaaggtga
    15061 atttgtctgt ggggggccta gaccgacgat tgtcgaagga aaaggaaaat gggcagagac
    15121 cttgcatctt gttgaggaaa atatgtttgg cagtagcatt gccaattatc gaaatagttc
    15181 cgaggataga tatgtttctt ctatttttca tgggatgtat aaacgagagg ttttccagaa
    15241 ggttggttta gtaaatgagc aacttggccg aactgaagat aatgatattc attatagaat
    15301 tcgagaacat ggttataaaa tccgctatag cccaagtatt ctatcttatc agtatattcg
    15361 accaacattc aagaaaatgc tgcatcaaaa gtattcaaat ggtttgtgga ttggcttgac
    15421 aagtcatgtt cagtttaagt gtttatcatt atttcactat gttccttgtt tatttgtttt
    15481 gagtcttgtg tttagtctag cattgttacc gatcacattc gtattcataa ctttactatt
    15541 aggtgcctat tttctacttt tgtcattact cactttgctg actttattaa aacataaaaa
    15601 tggatttcta attgtgatgc cctttctttt attttccatt cactttgctt atggccttgg
    15661 gacgattgta ggtttaatta gaggatttaa atggaagaag gagtacaagg gaacaataat
    15721 ttatttggat aaaataagcc aaataaatca aaatatgcta taataacaat atagtaaaac
    15781 tcttttaagg aggagtagat ttctatgaat aaaaaactaa cagattatgt gattgatctg
    15841 gtggaaattt taaataaaca acaaaagcag gttttctggg gaatatttga tattttcagt
    15901 atggtggttt ccataattgt atcttatatt ttattttatg ggctgattaa tccagcacct
    15961 gttgactaca ttatctatac gagtttggcc ttcttgttct atcaattgat gattggtttt
    16021 tgggggttga acgcgagcat tagtcgttac agcaagatta cggatttcat gaaaatcttt
    16081 tttggtgtga ctgctagcag tgtcttgtca tatagtatct gttatgcctt cttgccactc
    16141 ttctccatcc gtttcatcat tctctttatc ttgttgagta ccttcttgat tttattgcca
    16201 cggattactt ggcagttaat ctactccaga cgcaaaaaag gtagtggtga tggagaacac
    16261 cgtcggacct tcttgattgg tgccggtgat ggtggggctc tctttatgga tagttaccaa
    16321 catccaacca gtgaattaga actggtcggt attttggata aggattctaa gaaaaagggt
    16381 caaaaacttg gtggtattcc tgttttgggc tcttatgaca atctgcctga attagccaaa
    16441 cgccatcaaa tcgagcgtgt catcgttgcg attccgtcgc tggatccgtc agaatatgag
    16501 cgtatcttgc agatgtgtaa taagctgggt gtcaaatgtt acaagatgcc taaggttgaa
    16561 actgttgttc agggccttca ccaagcaggt actggcttcc aaaaaattga tattacggac
    16621 cttttgggtc gtcaggaaat ccgtcttgac gaatcgcgtc tgggtgcaga actgacaggt
    16681 aagaccatct tagtcacagg agctggaggt tcaatcggtt ctgaaatctg tcgtcaagtt
    16741 agtcgcttca atcctgaacg cattgtcttg ctcggtcatg gggaaaactc aatctacctt
    16801 gtttatcatg aattgattcg taagttccaa gggattgatt atgtacctgt gattgcggac
    16861 attcaagact atgatcgttt gttgcaagtc tttgagcagt acaaacctgc tattgtttat
    16921 catgcggcag cccacaagca tgttcctatg atggagcgca atccaaaaga agccttcaaa
    16981 aacaatatcc gtggaactta caatgttgct agagccgttg atgaagccaa ggtgcctaag
    17041 atggttatga tttcgacaga taaggcagtt aatccaccaa atgttatggg agcaaccaag
    17101 cgcgtggcgg agttgattgt cactggcttt aaccaacgta gccaatcaac ctactgtgca
    17161 gttcgttttg ggaatgttct tggtagccgt ggtagtgtca ttccagtctt tgaacgtcag
    17221 attgctgaag gtgggcctgt aacggtgaca gacttccgca tgacccgtta ctttatgacc
    17281 attccagaag ctagtcgtct ggttatccat gctggtgctt atgccaaaga tggggaagtc
    17341 tttatccttg atatgggcaa accagtcaag atttatgact tggccaagaa gatggtgctt
    17401 ctaagtggcc acactgagag tgaaattcca atcgttgaag ttggaatccg cccaggtgaa
    17461 aaactctacg aagaactctt ggtatcaacc gaactcgttg acaatcaagt tatggataag
    17521 attttcgttg gtaaggttaa tgtcatgcct ttagaatcca tcaatcaaaa gattggagag
    17581 ttccgcactc tcagtggaga tgagttgaag caagctatta tcgcctttgc taatcaaaca
    17641 acccacattg aataaaaaag aaaaacgcat attatcaagt taaacaacct tggtaatatg
    17701 cgttttatta tgtagagact tatactcttc gaaaatctct tcaaatcacg tcaacgtcgc
    17761 cttgccgtat atggttactg acttcgtcag ttccatctac aaccttaaaa cagtgttttg
    17821 agctgacttc gtcagttcta tctgcaacct caaaacagtg ttttgagctg acttcgtcag
    17881 ttccatccac aaccttaaaa cagtgttttg agctgacttc gtcagttcca tctacaatct
    17941 taaaacagtg ttttgagcag cccgcagcta gtttcctagt ttgctctttg attttcattg
    18001 agtattactt cattttcttc tgaaatggag ttgttaccca gtctatgcta ttgaaaatac
    18061 gccaaaactt ctaagggttt gtgagcgata taatcaggtt gatagtttag tagatctgct
    18121 tgctctccaa atccccaagt gacggccaat ttctgaatac ctgtttctcg agctcccagc
    18181 atatcaaact tggtatctcc gatgatgatg gcttgttctg gtgctagttg atgtgtctgt
    18241 aaggcttggt gaatgacatc tgccttatgg ggtgcttcag ggctagaacc ataaatacca
    18301 tcaaagaaat gatggatttc caagtttttg gccatgtctt gagcagtaga tgtattcttt
    18361 gtcgtggtga tgtagagtgg ataactgctc gataactcct caagcaagtc tataatctga
    18421 ggaaagagtt gagcttcata gatgcctttt gccttatagt aagaacgata tatctgcatg
    18481 gcttcagaaa tttggtcttt ggacaggcag gtcgcaaaac tactttcgag aggtggtccc
    18541 ataaaaccac gaatagtttt ggcatcaggg ctaggcaccc ccagctcttt aaaggtatag
    18601 gtaaaggcat tgtgaatccc gatagaacta tcaacgaggg ttccatccaa atcgaaaaaa
    18661 atcgctgtga tagaggtcat ggtttctcct atttgataag cttattctcc gaaaatctct
    18721 ttttggaggc gacgaccagt aggggtggta gcgagtccac cttcagctgt ttcacgaaag
    18781 gcagttggca tgcttgctcc tacttggtac atggcatcga tcacttcatc cacagggatt
    18841 ttagattcga tacctgccaa ggccatgtct gctgcgatga aagcaaagct agctcccatg
    18901 gcattacgtt tgacacaggg aacttcgacc aaacctgcaa cagggtcaca gatgaggcct
    18961 agcatatttt taatgacaaa ggcaatagct tgactggcct gataaggtgt tccacctgca
    19021 gccagagtca aggcggcagc actcatagca gaggctgaac caacttcagc ttgacaccca
    19081 ccctcagcac ctgagatgga ggcattgttt gcgatgacta gtccaaaggc accagcagca
    19141 aagaggaaat ccaattgttg ctcgtggctg aggtctaatt tttcaatagc agcagtgaga
    19201 acggatggca gacagccagc acttccagcg gttggagtgg cacagaccaa gcccattttg
    19261 gcattgtgtt cattgactgc gatggcattt cgggcagccg agagaatcgt ataatctgac
    19321 agagtttttc cgttttcgat gtagtgatcc aatttggcag catctccacc tgtcaggcca
    19381 ctacgagatt tattttcatt gaggccaagt tggacagagg ctttcataac ttccagattg
    19441 cgttccatga gaaggaagac ttcttcacgt tcgcgaccgg tcaattcaaa ctctgttgta
    19501 atcatgagtt ctgcgacatt tccttgaaag tccagatctg cttgctcgac caattctttg
    19561 atagaataaa acatgcttcc tcctatttaa agaaattgac attgtggaga tgagggattt
    19621 ttcgaatttc ttcgatagcc tcatcacagt tgcgactgtc aacttcgata atcataatgg
    19681 ctttttcacc agctttttca cgagtgacat tcatctgggc gatattgata ccatagcggg
    19741 aaagcgcctc tgtaacaagg gcaatcatac ctggaatatc ttgatgaacg atgatgatag
    19801 tcggtgtatt catattgaga gagacggcaa aaccattgag ttcggttacc tgaatatttc
    19861 ctccaccgat agaaatacca gtcacgctga tggtcttgtg ggcattttta acagtaattt
    19921 tagtggtgtt agggtgaggg gcattgctgt ctttctgaat ggtccagaca atcttgatac
    19981 cacgcttgtg ggcaatttcc agactatttg gaatttcagg atcatctgta tccattccta
    20041 aaatacctgc aacaagggct aggtctgttc cgtgaccacg ataggtcttg gcaaatgagt
    20101 taaaaagttg gaattcaact tctgtcggag tatcatcaaa aatggaagag acaatcttcc
    20161 caatacgaac agcaccagcg gtatggctac tagatgggcc aatcataact ggtccgatga
    20221 tatcaaagac agattgaaaa cgaagtgatt tcatcagttt ccccttataa aaattcttat
    20281 ctctattata tcaaagaatg aggggcttgg ctttaattgt ggatgaaaac ctttctaata
    20341 cctcaaatag cataaaaata gtatctttta tgacaaaaaa caccttattt agggaaataa
    20401 aaaataattt tgtaatattt ctacataaaa gtgtcaagaa acggtaatat ttaaagggta
    20461 tgatagaact atagaaagaa ggagaatttt cgaatatgaa atcaataact aaaaagatta
    20521 aagcaactct tgcaggagta gctgccttgt ttgcagtatt tgctccatca tttgtatctg
    20581 ctcaagaatc atcaacttac actgttaaag aaggtgatac actttcagaa atcgctgaaa
    20641 ctcacaacac aacagttgaa aaattggcag aaaacaacca cattgataac attcatttga
    20701 tttatgttga tcaaaagttg gttatcgatg gccctgtagc gcctgttgca acaccagcgc
    20761 cagctactta tgcggcacca gccgctcaag atgaaactgt ttcagctcca gtggcagaaa
    20821 ctccagtagt aagtgaaaca gttgtttcaa ctgtaagcgg atctgaagca gaagccaaag
    20881 aatggatcgc tcaaaaagaa tcaggtggta gctatacagc tacaaatgga cgttatatcg
    20941 gacgttacca attaacagat tcatacctga acggtgacta ctcagctgaa aaccaagaac
    21001 gtgtagcaga tgcctacgtt gcaggacgtt acggttcatg gacagctgct aaaaacttct
    21061 ggcttaacaa tggctggtat taagaactaa cgaacaaata atatgtaaag agtcgaggaa
    21121 atccctcggc ttttttatct ttccttcgct tggtaataga tctctacttc ttttttgaga
    21181 tgagacagca tagaagtttc ctcggttagc tctaggagtg agaaaccttt ttggataagt
    21241 ttcgcatcat ccctacaaat cccaataggg acatagcaga tagccagcct atcgtagctt
    21301 ttcttattct tggcgtcctc cagtaaagtg tagcagattt gcttacacat gtttttatct
    21361 tgattgtata gatagagtgt ggaaaggttt agcaggattg ctattcgcaa gtcatataaa
    21421 tgttgatagt ttttatagac ttctaagcgt tgcaagattt tctcggatta ttgacaaata
    21481 aacggatatt ctgatagacg attgccctag cggcttagtg taaactttac aaatttggct
    21541 tgtaattttt ttataaaatt cacttcagtt acttgacagt tattatattt tcacttatta
    21601 tatagataaa aggatgggat aggagtttaa aaatttgaaa gcgctatcca tattgtttat
    21661 tggactgatt cttgagtaat agttagagtg tgcttaatac tactctggtt gttcaaggac
    21721 ctgatacaga agcgcaccat tctcccggtt aagagtaagt tcgttgttaa aaatgaaatg
    21781 agatagaagg aaggtgagtc caatggacta cgatacttgt tgataaatta ctatagctgt
    21841 ttttacggaa cagctctcga taataggaga aataaatcat gagaaaatta gttaaaattg
    21901 gtgttgcatc tttaatggta tgtggtatac ttgctactac aaatgcttta gcagtatggg
    21961 ttgagggtgg tcaatggaac tatggagtag gttggacagg aacttttgga tattctgatt
    22021 acttacattc tactcgatat catacagcaa ctgttagaca tgggggtaga acctctaagg
    22081 attatgcaaa acctgaggca tgggctagag cttccctcac caagattccg ccaacaggaa
    22141 tggaatattt ctatggattt gagtaaaatt cttccctctc ctatttggag agggaaaact
    22201 gtagtggagg cacttttatg aaaaaaatca gtaatttctg tatgttactc ctgcttctgt
    22261 gtaccacttt ttttgttttt aatgtaaact atacacgaga agtggttcgg attcaagaaa
    22321 tgggaaagac tgtagattct ttggatttgt atttgaaaga tattaacgaa cctgcagcgt
    22381 ctgttcttcg attttttgag gatgtatcaa aggagtataa agtctccatc atcaaaacag
    22441 acagtggtga tgaggtggtc aagtctggtg tttttgataa agataccttc ccctaccaag
    22501 agtttgggat ttcttctctt gattttacca cagatggtga aggagtctat agtaataaag
    22561 aaatttccaa taaacttggt acgattccga cctttctaaa agccaaacct attcagctta
    22621 tgacttttca aacctatatc aaggatacat ctcgtagttt aaatggtcgc tatacgataa
    22681 cttctacaca agagatggac aaggatagga ttgtacagaa atggagcgat tttttcaaga
    22741 tagaccaggc taccttgcta gagccgacct acaaaagtgc agtggaagtc ataaatcgag
    22801 atttgctttt atctgccatt gtttttgtct tggctatttt gcttcttgtg ttagtgacag
    22861 tgtatcaacc gatgatggag atgaaaagag ttggggtaca aaaattactt ggttttcaag
    22921 atagggctgt tttagctgat gttgtaaaag gcaaccttta cctcctccta ggtggggctc
    22981 ttgtgatcaa tctaggcgtg tttttcttgc ttgattataa gccaaaagat ttgtttccta
    23041 tgctgtggtt gtctcatttt ttgctgttgc agctttatct ctttatcagt tggttgactt
    23101 acctcttaat ccaaaaaatg acaatcagct ctctgctgaa aggtttttca tctttcaaat
    23161 ttggtcttat cttcaattat gtgatgaaaa tagggacaac tattttactg acggccttac
    23221 tgattggggt gggcagaagt ttagaacaag aaaacaaaga acttgcttat cagcaacagt
    23281 gggtaagtca aggtaattac ctgaccttag aaaccttcaa actcaatgat aatctgtggc
    23341 aagaagagct agcagggtca gggaaatcta cagattattt ctatcgattt tatcaggatt
    23401 tggtagaaaa aacgcaggcg ggctatgtgc agagtagcag tcttcctgta aaaaattttg
    23461 tccaatcaga acagattcag caatatcagt taacagatac ggtggatgtt tactatgcca
    23521 atcgcaattt tctaaagagc aagggattca agctaccaga taccggtatt aaaaaagtta
    23581 ttttgatgcc agcaagtacg aaaggtgaag aagataaaaa tcagctcttg gggaagttaa
    23641 ttgcctttca ttcgatgaag tatgaagagc agcaaaaacg aacgatagag gagatggatg
    23701 tcgagattgc ctattatgaa ggagattggt catttttccc atatagtgat aagcgaaagg
    23761 aaaatctctc caatccaatt attagcttgg tcaatgattc tgatatgatg tgggatgaga
    23821 aagcctccct gtcaacaact ggcttaaata atccgattaa aattgaaaat acggttcaac
    23881 atcaaaaaga gattacagag ttagttgaga aattgtcaga tggaaattat ttaaaatttt
    23941 catctattca agccattcaa caagagaaag tggattctta tagagatgct gttcggaatt
    24001 ttaacctact ctttgctttg tttggtctcc ttagcatgat gatttcctac ttcttactag
    24061 taacaacttt cttattgaag cgcagggata tcattaccaa gaagtttatg gggtggaaac
    24121 tggtcgatcg ctaccgtcct ctcctcgttc tgctcttgct gggctatagt ttccctcttc
    24181 tagtcttgat tttctttgcc catgcgttct taccacttct actgtttgca ggttttacat
    24241 gtctggatat actatttgtg ctaggcttag cttctaggat ggagaaaaga agtctagtag
    24301 agttattgaa agggggcatc ttatgattga gttgaaaaat attaccaaaa ccattggggg
    24361 aaaagtgatt ttggataact tatctctcag gattgatcag ggggatttgg tagctattgt
    24421 tggtaagagt ggtagtggga agtcgacctt gttaaattta ttgggtttga tagatggtga
    24481 ttatagcgga cggtatgaga tttttggtca gacaaatcta gcggttaatt ctgctaagtc
    24541 gcaaacaata atccgtgaac atatctctta tctgtttcaa aattttgccc tgattgatga
    24601 tgaaacggtc gagtacaatc tcatgctggc gctgaaatat gtgaaattgc ctaagaaaga
    24661 caagctcaaa aaggtggaag agattttaga gagagtaggt ttgtcagcta ctttgcatca
    24721 aagggtctcc gagttgtctg gtggcgaaca acaacgaatt gcagttgcta gagccatctt
    24781 aaaacccagc cagctgattt tagccgatga acctacaggt tcgctggatc ctgaaaatag
    24841 agatttggtc ttgaagtttc tcttagagat gaatcgagaa gggaaaacag tcattattgt
    24901 gacccacgat gcttatgtag cccaacaatg tcatcgtgtc attgaattgg gcgagggaaa
    24961 atgagttcat tcagctcctt ttgactggct gaatactcat gttttccaga gaaaaatagc
    25021 ataaatacgc ctaggaatga cattttatgt agtatttcta ggtttttttt gtttcaaatt
    25081 gaaaattttt tcaatttagg cttgacaaag gatgaatata gatgtattgt ttatacaaac
    25141 aaaaggaata aacataaagt aggctttatt atgaataaga tgaagaaggt gttgatgacg
    25201 atgtttggtt tagtgatgct ccccctacta tttgcttgta gcaacaatca atcggctgga
    25261 attgaagcca tcaagtccaa aggaaaattg gttgtagccc tcaatccgga ttttgctcca
    25321 tttgaatacc aaaaagtggt tgatgggaaa aatcagattg tgggttcaga tatcgaatta
    25381 gccaaggcta tcgcaacaga actaggtgtc gaattggaac tatctcccat gagttttgat
    25441 aatgtactgg ctagtgttca atcaggaaaa gccgaccttg ccatatcagg tgtttctaag
    25501 acagatgaac ggagcaaggt gtttgacttt tccattccct actatactgc aaaaaataaa
    25561 ctcattgtca aaaaatctga cttgactact tatcagtctg taaacgactt ggcgcagaaa
    25621 aaggttggag cgcagaaagg ttcgattcaa gagacgatgg cgaaagattt gctacaaaat
    25681 tcttccctcg tatctctgcc taaaaatggg aatttaatca cagatttaaa atcaggacaa
    25741 gtggatgccg ttatctttga agaacctgtt tccaagggat ttgtggaaaa taatcctgat
    25801 ttagcaatcg cagacctcaa ttttgaaaaa gagcaagatg attcctacgc ggtagccatg
    25861 aaaaaagata gcaaggaatt gaaagaggca gtcgataaaa ccattcaaaa gttgaaggag
    25921 tctggggaat tagacaaact cattgaggat gcctttaaag catccattga aaaatagaaa
    25981 gaaggaaaag aacatgagta aagaaaaagt aattttggcc tattctggcg gtttggacac
    26041 atcagttgct attacctggt taaagaaaga ctatgatgtt gtttcagttt gtatggatgt
    26101 gggtgaaggg aaagacttag atttcatcca tgataaggct cttaaggttg gggcagtaga
    26161 atcttatgtc attgatgtta aggacgaatt tgctacagat tatgtgctag tggctcttca
    26221 gtcacatgcc tattatgaac aaaagtatcc cttggtatct gccttgagcc gccctctgat
    26281 ttctaaaaaa ttggttgaaa tagcgcatca gataggagcg actacaattg ctcatggttg
    26341 taccggtaag gggaatgacc aagtcgaata ccagattgca gtcgctaaga aagcgaatga
    26401 agctaaaaag tgatggagtg atgggttcag aataagaggt tggtagatta tcagcctctt
    26461 tcttgtcgtt gaaaaagtga gatatattga cttttgaaaa aaatgtcata attgagttgg
    26521 gataaacgta aaagtcatac tttctcgtta aatcgttcgg cgattctatg aaaaggtcga
    26581 ggagctccct cggctttttt atctttcctt cgcttggtaa tagatctcta cttctttttt
    26641 gagatgagac agcatagaag tttcctcggt cagctctagg agtgagaaac ctttttggat
    26701 aagtttagaa tcgtctgtac aaatcccaat gcggacatag cagatagcca gcctatcgta
    26761 gcttttctta ttcttggcgt cctccagtaa agtgtagcag atttgcttac acatgttttt
    26821 atcttgattg tatagataga gtgtggaaag gttgagcagg attgctattc gcaagtcata
    26881 taaatgttga tagtttttat agacttctag gcgttgcaat atttttccag tgatgagatg
    26941 gaggtattca atgggaaaac tgaaaagaat ggtattgagg atttttagat cactctcata
    27001 ccatgtatct tgtttttcaa tttttctcca aagttttttg acaacctgtt ctgcgtgatc
    27061 tgatagttcc cctgccccgt gttgacggat ataaatgaca acttcaagca tatctctgat
    27121 ttcttctata gggagatcgt ggtgggtctt gaggtagtct tggcattttt gaaataaatt
    27181 gacaagatcg ctggtcccga taatggaacg catattgaga taggtttgca taatctctgt
    27241 gcgttgactt ggttgataaa gttgacagat atattcaaac tcttcaaaac tcatattgat
    27301 ttgacggaga agaaattcca tattttcata ttttggggtt gtcttgccac tttcgatttt
    27361 tgataagctg gttcttgaga gaacaccccc acagacctct tcttgggtca gcccctttga
    27421 ctcacgtatt tctttataga cctttccgaa atcataacgc atgattttct cctttctgtg
    27481 aaaaaagtta acaaataata aaatcttgtt aaaaatattg tatcatagca atgtaaaaag
    27541 taaaaaagaa agtcgaaata aatttgtgaa aaaagttaac gtaattttaa aatgagctta
    27601 ataagaggta tgatgtaggt agaaaataaa gataggagaa aaagtatgaa taaaaaaata
    27661 ttttgtattc tagtatgtat gatatcattg attagtctgg tcataatctt tccatggggc
    27721 tggtcgatat aatgtaaggg agcttgagtt gttaaaggag gctcagtcct tggacaaaaa
    27781 tctgctgtac tacaatgctt ggaaagatat caagaacaaa gaatgatacg attgaaaata
    27841 aactgattca agaactactg ggcagtgatt gaggtttggg tgacatcaaa gaaaagttag
    27901 attaattcta aagaattgag tatttctatg ttaaaaaaat atccttgtac gatgcaacat
    27961 gatcagtcag attgtgctgc ggcagttgtt tcaacagttc ttttatctta caaaaaggaa
    28021 ctatcaatca tgaagattcg ggaaattatt ggtacagaca tgtatggaac gactgtcagt
    28081 ggtattgttt caggtctgaa taagttgaat tttacagtaa aagctgttcg agtggcactg
    28141 gaagatttga ctccaaaatt aacatttcct gcgattcttc aagttaagaa tgatttaggt
    28201 caaaatcatt ttgtggtatt acatagtata aaggagaaaa taaatggaac tcgtattacc
    28261 aaataattat gttgctcttg agcaagagga gatgatgtat cttgatgggg ggggcttatt
    28321 taagcaagag tgcttgtcaa ggaatttgcg cagctttagc tatgagccca ggaactttta
    28381 tagcattgac tggagctgca gttttaacaa aaaaactaat aaactatatt aaggttggag
    28441 gccttggagg ttggcttatt ggtgcagcag caggtgtatt ggctcttatc tttttgataa
    28501 aaatttgtgt agatactacg ataaaggttc tattaaacag aatctttaag gcaagtaagg
    28561 taatgaaaag gaggatattt tctctttttg tactagattt gatggtctat atatttttag
    28621 gttatgtttt agtgatacaa aaagacgtat atctgttttc aattctgata attttttcta
    28681 atttttcagt tccctttatc agagaaaaag agtatgaatt atttaaaaat aagaaatgag
    28741 atagatatgg tagctttatt aaaactgaga ataaagtttg ggagatattt ttatttattt
    28801 taggtgtgtt gttaattgta atttcattac taagtccccc aaaaattaaa ttttggaaat
    28861 agagttagtg agaaggatag gataatagta ttatgttgat tgttttaatt tcagttattg
    28921 ttgcattact gtatcataaa attacagagt atgtcaacaa caggaaaatt gatattgtta
    28981 tttttctatc attgctgatt tctcatttta tttggaatta ctatttttta ccaattgaaa
    29041 tattgatagc aatcagtgga gcaaatttac tattaagttt tttaaaaaaa ttacagacta
    29101 aataatatta atctgtgtaa tacagtagct cggtcattag attctattga agatataaat
    29161 taaaaatgag gctgggaaaa aactcaattt gaaaatgaga ttgagtaaat ctttctatct
    29221 atataacgta tatcatcaat atttttgaac acctgataat atgcattttt cttattttaa
    29281 agattttttg cctttcttca tttcttgaat gaattggaga gatgacttta tttaggtgtt
    29341 tgacattact atagatagga tttagcagta ctaatatgaa ctcatattat aggtgtagac
    29401 ttaaattttg gaagcaagct aaaggatatc ttatctaggt aactaagtgc tataacaaga
    29461 tatattggtg gagttagtat ggcaactatt actaatgctc ttaatattgc ggctactgtt
    29521 gctgaagtct tctcattagg aggagccatt gcatatggtt tagatatcgt agacggtaaa
    29581 tttgatgggt atttatgggc gtaaaactat agctatgaaa catttttttg caggaattgg
    29641 tgaaattcat tttttgttat ttttattata tctaagcatg tctgctagtc caattattgg
    29701 actagtgatt ggatatacta aaataaatct aataaattct attattatag ctcttggtat
    29761 gatattggca ttaattttgg tattatcaag agtgtataga aaatattttt atagagacga
    29821 tgatgactaa agtttttatc aataatttgg gctccttgtc aactgtagtg ggttgaataa
    29881 aagctaacgt ctggggaagg gtttaaagct ttgctttatc aaatattgac ttacagagtt
    29941 gctctattgt attgatgcat tcttagtaaa taatatggtg ttttgaatga aagatgatca
    30001 gaaatattta ttagcgggac tttattcgct tctagttgca atattttatt ttccattgat
    30061 tgattccaag gggatttttg taagtatatt gatggcggtt ttacttttat atttaatata
    30121 cttcattgca acagtcattc atattgtgat aattaagttt ataagaaaaa aatcttttaa
    30181 gtatttggtt ctatatccat ttacttatga tgggagctgg agatttcaac ctataaactt
    30241 actctacttt ccagaaatgg tgagagatgt cattccgatt aatttagttc aagaatattg
    30301 ccaaggacaa ccttacggac tgttaaaaaa gatgctgaaa agaattcgat tgtcacgaga
    30361 gatatcttta ctcctggcta ccattatcgt ctattttttt acgcatagaa ttctaccttt
    30421 ttcagtattt acgttcatgt tttcttatat attgctattt gtacaatctt atttgggtgg
    30481 taataccgct tggattggaa atagaagatt aataatagat gatgaatttg aaaaaatctt
    30541 gctttcaaaa agttatataa aagaaatatc atctgcacga tactcagaat acttgacatg
    30601 tgaatacaaa aactttacac caatcatatt gttagctatt tttgaaaatt tgcttgactc
    30661 ctacttgctt cagaatcaga gtgaggttga cttagatatt ttttataaag ttttaccttt
    30721 gctttataaa gaaaaatata ctatgggatt caattacttt gtaagtttaa attatttact
    30781 atataaggtt ggatttttgg gaatcattta cgataatgaa gcattaagag atttgtcaaa
    30841 acaatattta aacaaaaata tttcggaatt acaagatggt tctttcgagg gcggtataca
    30901 agatgctgtt gcctctaaac aaatagtagt tataaatgaa tttatagctt gtttaaattc
    30961 cagatgcatg ccatcccaat atgatagatt tttttataaa gatagacctt atattttttc
    31021 cagaaagagt cctattaagg ggtgaaaatt tgttacattt ggattaacaa gtgtcctagg
    31081 gattagaaat aactctagta tagctagata tttttgagta actagaaata tcattagtct
    31141 acccatatga ttgccagaaa agatggctga tgaatcttat ttatactgtt gcagtaggcg
    31201 ttgtctagga taaataagct atcttgatgg gggagattgg aataatttta gtagaaacat
    31261 taaaggatta tggacaagta gcgtaggatt aggtgatgca atgtgctaag ttggcttggt
    31321 gttaacagta gtattattta acaatggaaa gtagactaaa tgaaaaataa gcgttatttt
    31381 tttgacacaa ttttaataat tttactgctt ataagcacga tattttgtgt cagcccagta
    31441 tttataaaat tggacatctt aggaactccc tctcatgcca tcttaacctt tgtattggcg
    31501 ataccgttat tctatatttt gtctcaatgc ttacatactt tgctattact agtttcctca
    31561 atcttttgta aattaagacc aatttatttt tattttatat ttgtgatcat tataggagct
    31621 aggaaatact atcgaattct ctttcaccaa ctaatgggat ttagtccagg aatagcagtg
    31681 ttttataagg agagtcaaac aactaagaat ctgtttaaat tttactactt cttgtacttt
    31741 acaacactaa tttcatacta ttttttcttt acttttgtgt atgacaaacc gttgcttttg
    31801 cctcttattt cattttctat tatcatagca ttagtacaaa aactttatag aattgagaat
    31861 caacaattat ttctgttaaa atcaaaggta ctaacaatac tggaatctaa gaagaattgt
    31921 gagtttaatc ttcaggatta tcatgaaatt tggaaattgc aatcaaaatc tgagttgcca
    31981 tgcgtggctt tatcttatat cagtttaatc aagccatatc tttcagagag tgtgcgtgaa
    32041 caaattgatt tattagaagt taagcaattt aaaaaaataa ataatccaat atcactttat
    32101 ggtatgttgg atgttataaa attaaatcta tatttacggc attataatga aaaaaataaa
    32161 tatgaatcaa tgttaaagaa aattttagag gtaagaccag actttgtttt aatcgagcag
    32221 aatattgatg atagtttaaa tagctcgcaa ccattatctt tatctttagc catttcagaa
    32281 atccaacttt tgcttgaagt gtatataggg atcaaacatg tttcaattag gagataaaac
    32341 tagaataata tttgccatta taggggcaag ttgcatatta gtcagtatgt atcttattcc
    32401 acttattaaa actgagaata aattttggga aatactttta tttatattag gtgtattgct
    32461 aattggaatt gcgttactaa gtcaaaaaaa ataaattttg aaatagtatt agtgagttcg
    32521 caatcattta ttgctagtgg tttagaactg ttaagtttca aacaataatt gattttaaac
    32581 cttaggtaac ctataaaaac aaataaggta gagaaaggat atcttatcta ggtagctaag
    32641 tgataaaaac acagtcgtct atcacttgtt aggaaacgat cctaactatg cttaataaaa
    32701 aaggagaaaa taaatggaac tcgtattacc aaataattat gttgctcttg agcaagaaga
    32761 gatgatgtat cttgatgggg gattttctat tctgagatgg cctgttgcaa cagccattaa
    32821 tatagctttt aatggtgttt taggtggagg agcaatcagt ctagttagaa attatattcg
    32881 taattatggt ttgcggcgag ttacaagcgc aattgctgga gcagctgcaa gatatgttgg
    32941 ggtacgagtt gcaaatagag tggcaggatt tgcactgtct gctattaatg gatttgcagc
    33001 ttggatgtca attggcgatg ctattacaac aatctgggcc aacaatgatg taaataggag
    33061 agacccaaat ttaaacgcct tgtggtaact agatatgggt attaaaatgg aaaaaatttt
    33121 tgttattatt ttttttgtat gtctatttat atcatccata acttttttag cctatgattt
    33181 tgttagcgaa gaaataaaaa agttgattat ttggatgaat gtcgtttttt tgattttaat
    33241 catagcaatg ataatttatc caaaattaag aaaatgataa ggacactgta aaattatgat
    33301 acgtaaacta atcatttttt tattaatgct ccctcttttt gtcttgtggc tagagttgca
    33361 tttgttagtg agtaacttgc aattgaatct agaaattccc cttgattttg tggttagtac
    33421 gagtcttgct ttctgtagtt tgattttatc aaaaatagtt ttagacatac tatacgcatt
    33481 gaaagatttg tacaagaaag aagctcttat tacgattttt ccttttattt ttataggcag
    33541 gaagaaagta aatgtgaggt tctcgcccta tttttcattc catcgtaaaa gtttgtcgcc
    33601 tgatgattta agatctagga ttatatggag ttttattctt gaaattgcta ttattctagt
    33661 atttatttta aaaattcctt ttgcaatcat catgcttact acaatatttt tctggactat
    33721 aatggatatc aatcatctcg tttttaataa gacggaattt ctttttaatc aaaataaatg
    33781 ggaaaaagaa gattcgtttg aaagcgattt gacgaaaacg ttaaaggata agatacaaaa
    33841 atcagagcta agttattctg acttaatgtc tcttcagctg tatgatgcga tgaaccaatc
    33901 caccttttta acggatagtg aactttttga ggatattttg aaaaaaatcg aagattctca
    33961 taacaccctt ctgtgtacag gtcttgtcga gttactgctg tatgaaatgt ctattagtaa
    34021 caataacaac tggtccaaca aggttgataa aattaggata cacctcatca gaatcaatca
    34081 attagatttt ttctattata caagttggtt aaggcaaaat tttgatttct gtatgaatag
    34141 agagtatcat aaaatgaaat ctcggaaatt attactgagt aataaaaaga tagtttaagt
    34201 tcgtcctatt tgtaaaacaa atgaaacaat ttcaactaag gaggagaaaa caaatggaac
    34261 ttgtattacc aaataattat gttgtgattg atgaagaaga aatgatgtat cttgatgggg
    34321 gagcttattt aagcaagcgt gcttgtcaag gaatttgcgt agctttagct atgagttcag
    34381 gaacttttat agcattagct ggagctgcag ttttaaccaa aaaactaata aactatatta
    34441 aggttggagg tcttggaggc tggcttattg gtgcagcagc aggaaaaata gcttactgta
    34501 ttggatatgg tgctcttaat agaggttgtg atattagcgg gaacccttat ccttgggatg
    34561 gatttatatc tgcgacagta agatgaataa tgtagataag attcgaaaaa tacatattat
    34621 cgtatgttgg gtgtatatat ttttatcatt cagggcgatt ataaatgaca cggagtattt
    34681 tttgcttatt tttttagctt ttatctactc aatagtatca ctacctctat attctgtgaa
    34741 aaataaaata gtatctatct gtctagccat aaattcgatt ctgttaatga gtttccccat
    34801 tttaatcaat aagtttttcc cagaaagttt tttgacttat accgtattaa taagtgtttt
    34861 tatcctagag ttagcaatct ttcatttaat tggggaagat tttgctacta aattgactaa
    34921 cgaatataag aaaattagtc agtttagaag caaggtgtct caatcttctt ggataaaata
    34981 tttagagatt tctagtttta tattaactat atttccatct attctttacg gtacagttga
    35041 taatcgtgta ttggctctta tctttttgat aaaaatttgt gtagatacta cgataaaatt
    35101 tttattcatc agattatttg acacaagtac tttaatgaag aggagaatat tttttctttt
    35161 cgcattggat gttatagctt acttattttt aggatatctt ttagtgattc aaaaagcagg
    35221 ctatttgttt tcggttttac ttcttttttc taatttttca gttccattta tcaaagcaaa
    35281 ggaatacgaa ttatttaaaa atagcaagta atagaaacat aggttaaatc ttagaacggc
    35341 ttaaaatcag atatgataaa gggaaatagt cttatctagg taactaagtg ctacaaacac
    35401 agtcgaggat cacttgttag gattacattt taatcatgct taataagaat ggagaattcc
    35461 tatggggatt gtattactct gaagtttcga ataccttagt tctcgtgatt ttgagctgtt
    35521 ctagctttag aatccttcag aatgtaaaat tttaagcagt caaagactta gaatagcctg
    35581 gaaacattta ttttatagca attctaggct tagaattgct catatatatg tatttgagct
    35641 gctcgatagt taggacagct ctattctgag aaatctgagc tatcaatgct tcagaatagt
    35701 atttcgcaaa tggtttttat tgaagaggtg attgtgttat gatagtctaa aataaaactg
    35761 atttaatgga gtaaatggag aatcgtcaca tgaaacattt ttttgcagga attggtgaga
    35821 taaaacttgt tggctactta ttgtatatat gtgtaggact agcccttctt tttcatatat
    35881 atgtcatagg ttcggaactg agttttgtga aaatagtgtt atctattttg ggagttatat
    35941 ttgtaagtat gttaactatt gctcgaattt atcggacttt tctataaaga atagtttgga
    36001 cttgaactgt atctaaaaac agaggttggt cgattatcag cctctttctt gtcgttgaaa
    36061 agagtgagat atattgactt ttgaaaaaaa tgtcataatt gagttgggat aaacctaaaa
    36121 gtaatatagt agattgaatc tggaatagtc cgttatgact gttaaaatat ttctagaaat
    36181 taatttgact ttcctaatcg atttgttcac atcttgtttc aatctactat actttctcgt
    36241 taaaccgttc ggcaattcat ggtgacatgg acacatagta gtaagcacac tatgtggctt
    36301 ggcagagcta aaaactgttc ccttgcgata agcctaataa gcacaacata gggagttaga
    36361 gaagccgact ctaatcaacc actttgggca gtagtgagaa ctgccccgtg cttttttatt
    36421 ttgagaaaat atggagtttg tcgttgaaat tacttgattg tattttggac tatcaagaaa
    36481 gattcaatgg aaaaacatgt caagtatcaa cgaattataa gtatttagag attttcaaag
    36541 tgaatttttg cttgactgat ttacatcatt tatttgactt atacaaaatc acacgagatt
    36601 atgctagtca aacaaaacct gctattcaag ctggtgtttt tattttagaa gattttagaa
    36661 atatcctatg tacaatgatg taatcgaaag gatatcttta tatgagttta tcggtgatat
    36721 tttctattct aaaataataa gttgttgcat cgtagctagg gatttatcta aaaatactat
    36781 gaaattggac gtcatatttt ttgaggataa aaataaaaga tccgcagttt taggtttacg
    36841 aagagacaaa agcggagtat ttaaatcagt tactctacat tttacaagcg ctaagaaata
    36901 tgctaaagtt cgtaaaacag atgtgaaaga aatgaaatgg ctataaagat tgtccgcagg
    36961 cttaagcttg cgttttttgt tgtttaacga aattaaaaaa caagctctct catcggaaat
    37021 gtttttatag gaatgaagga agatgatgct atgtttaaaa agagaatcga aaagggcaaa
    37081 agtagtatct ttatctattt tttggagtag aagcttatga tatagaaatt tgtaataaaa
    37141 atgtaatata aaacatttga caaatattta cggggggagt atacttaata taagtatagc
    37201 ctaaaaatga ctatcagaaa agaggtaaat ttagatgaat aagaaaaaaa tgattttaac
    37261 aagtctagcc agcgtcgcta tcttaggggc tggttttgtt gcgtctcagc ctactgttgt
    37321 aagagcagaa gaagctcccg tagctaagca gtctcaagct gagagagact atgatgcagc
    37381 aatgaaaaaa tctgaagctg ctaagaaaga atacgaagaa gctaagaaag atttagaaga
    37441 agcaaaagct gctcagaaaa aatatgaaga cgatcaaaag aaaactgaag agaaagcaaa
    37501 gcttgttcaa aaagcggatg aagagcgtca aaaagcgaat gtggcagttc aaaaggcgta
    37561 tttaaaactc cgagaagcac aagaacaatt gaacaaaagt ccaaacaata agaaaaatgc
    37621 cgctcaacag aaattaaaag atgcattagc tcatattgat gaggtaacat taaaacaaaa
    37681 agaggcggaa gcgaatttta ataaggaaca agcaaaagta gttcctgaag cagataagtt
    37741 agctgagact aagaaaaaag cagaacaggc tgaaaaaaaa gaaccagaac ttgctaaaaa
    37801 agtagcagaa gctaaagcaa aagcagaaga agctgagaaa aaagctgttg aagccaaaca
    37861 aaaagtggat gctgaaaaat atgctcttga agctaaaatc gctgagttgg aatatgaagt
    37921 tcagggacta gaaaaagagc tcaaagagat tgatgagtct gactcagaag attatattaa
    37981 agaaggtctc cgtgctcctc ttcaatctaa attggatgcc aaaaaagcta aactatcaaa
    38041 acttgaagag ttgagtgata agattgatga gttagacgct gaaattgcaa aacttgaaaa
    38101 agatgtagaa gatttcaaaa actcagacgg tgagcaagct gaacaatatc ttgttgcagc
    38161 taaaaaagac ttagatgcta aaaaagctga attagaaaat actgaagctg accttaagaa
    38221 agcagttgat gagccagaaa ctccagctcc ggctcctaaa ccagccccag ctccagctcc
    38281 aactccagaa gccccagctc cagctcctaa accagctccg gctcctaaac cagccccagc
    38341 tccagctcct aaaccagctc cggctcctaa accagctcca gctcctaaac cagaaactcc
    38401 aaaaacaggc tggaaacaag aaaatggtat gtggtacttc tacaatacgg atggttcaat
    38461 ggcaacaggc tggctacaaa ataatggctc atggtactac ctcaacgcta atggtgctat
    38521 ggcaacaggt tgggctaaag tcaacggctt atggtattac ctcaacagca atggcgctat
    38581 ggcgacagga tggctccaat acaatgattc atggtactac ctcaatacta atggtgctat
    38641 ggcgacaggt tggctagaat acaatggttc atggtactac ctcaacgcta atggtgctat
    38701 ggcgacaggt tggctagaat acaatggctc atggtactac ctcaacagca atggcgctat
    38761 ggcgacaggt tggctccaat acaatggttc atggtactat ctaaacgcta acggcgctat
    38821 ggcaacaggt tgggctaaag tcaacggttc atggtactac ctcaacgcta acggttcaat
    38881 ggcaacaggt tgggtgaaag atggagatac ctggtactat cttgaagcat caggtgctat
    38941 gaaagcaaac caatggttca aagtatcaga taaatggtac tatgtcaatg gcttaggtgc
    39001 ccttgcagtc aacacaactg tagacggata tactgtcaat gaaaacggtg aatgggttta
    39061 agccgattaa attaaatcat gttaagaaca tttgacattt taattttgaa acaaagataa
    39121 ggttcgattg aatagattta tgttcgtatt ctttaggtac ctatcttatg atttcaggaa
    39181 atgtcattaa aaaaacgact ccttttctct aacttgaaaa atagattaga gaaaatgggt
    39241 tgttttattt attatagtta tttgaatgaa gataagaaga aggtatactc acatcattca
    39301 cataatctgt atattgacta taagttttaa aaaacaattt ttaagctctt ccttgtcttc
    39361 tctaaccaag cgtgttataa tgaatactgc tcaagcgacc ttcaatcgtg aagcacacac
    39421 gaccttcaat cgtgaataaa cgaatagatg ggagacttac catgagtgat aactctaaaa
    39481 cacgtgttgt cgtggggatg agtggtggtg ttgattcgtc ggtgacggct cttttgctca
    39541 aggagcaggg ctacgatgtg atcggtatct tcatgaagaa ctgggatgac acagatgaaa
    39601 acggcgtctg tacggcgacc gaagattaca aggatgtggt tgcggtggca gaccagattg
    39661 gcattcccta ctactctgtc aattttgaaa aagagtactg ggaccgcgtt tttgagtatt
    39721 tcctagcgga ataccgtgca gggcgcacgc caaatccgga cgttatgtgc aacaaggaaa
    39781 tcaagttcaa ggcctttttg gactatgcca taaccttggg ggcagactat gtagcgactg
    39841 ggcattatgc tcgagtggcg cgtgatgagg atggcactgt tcacatgctt cgtggcgtgg
    39901 acaatggcaa ggaccagacc tatttcctca gccaactttc gcaagaacaa cttcaaaaaa
    39961 ccatgttccc actaggacat ttgaaaaagc ctgaagttcg aaaactagca gaagaagcag
    40021 gtctttcgac tgctaagaag aaagactcga cagggatttg ctttatcgga gaaaagaact
    40081 ttaaaaactt tctcagcaac tacctgccag ctcagcctgg tcgtatgatg actgtggatg
    40141 gtcgtgatat gggcgagcat gctggtctta tgtactatac aatcggtcag cgtggcggac
    40201 tcggtatcgg tgggcaacac ggtggtgaca atgccccttg gttcgttgtc ggaaaagatc
    40261 taagcaagaa tattctctat gtaggccaag gtttctacca tgattcgctc atgtcaacca
    40321 gcctagaggc tagccaagtc cactttactc gtgaaatgcc agaagagttt acgctagaat
    40381 gtacggctaa attccgttac cgtcagcctg actctaaggt gaccgtccat gtcaaaggag
    40441 acaaggcaga agttatcttt gcggaaccac aacgcgcgat tacaccagga caggcagttg
    40501 tcttttacga tggcgaagag tgtctaggtg gcggtttgat tgacaatgct taccgcgatg
    40561 gacaagtttg tcagtacatt tagattgaca aattttctca atttgctaca ataataacag
    40621 caatagaaat gatggtcaaa gctcatggat gttgcaggct tttttgtcct gcacttcttt
    40681 ggagttttga ctgtttttgt gtcgtttaag ggaaaggaca agaatgactc aacaagactt
    40741 tcggacaaaa gtagacaata cggtttttgg tgttcgggcg acagccttga ttgtccaaaa
    40801 tcacaagctt ctagtcacca aagacaaggg caagtattac attatcggcg gtgcgattca
    40861 agttaacgaa aaaacggaag acgcggtagt ccgtgaagtg aaggaagaac tgggtgttaa
    40921 agctcaagct gggcagctag cttttgtggt tgaaaatcgt tttgaagtgg acggcgtttc
    40981 ctatcacaat atcgagtttc attatctggt ggatttgctt gaagatgccc cgttgaccat
    41041 gcaggaagat gagaaaaggc agccctgtga gtggattgac ttggataagc ttgaggatat
    41101 ccagctagtt ccagcctttt taaaaacagc cctaccagat tgggaaggcc aactaagaca
    41161 cattcatctt gaggaatagg agagaaacat gacttatcat tttactgaag aatacgatat
    41221 tattgtaatt ggtgcgggac acgctggggt tgaggcttcc ttggccgcta gccgtatggg
    41281 ctgtaaggtc ctgcttgcga ccatcaatat tgaaatgctg gctttcatgc cttgtaatcc
    41341 ctctatcggt ggttctgcca aggggattgt cgtgcgtgaa gtcgatgccc tcggtggcga
    41401 gatggccaag actattgaca agacttacat ccagatgaag atgctcaaca cagggaaggg
    41461 gccagctgtt cgtgctcttc gtgcgcaggc tgacaaggaa ctttactcta aggaaatgcg
    41521 caagacagtt gaaaatcaag aaaatctgac ccttcgtcaa accatgattg atgagatttt
    41581 ggtggaagat ggtaaggttg tcggtgtgcg tacagccacc catcaagaat atgctgctaa
    41641 ggctgttatt gtgacgacag ggactgctct ccgtggggaa attatcatcg gagacctcaa
    41701 gtactcatca ggtcctaacc acagcttggc ttctattaac ctagctgaca atctcaagga
    41761 actgggtctc gaaatcggtc gtttcaagac aggaacccct ccacgtgtca aggcctcttc
    41821 tatcaactac gacgtgacag aaatccaacc aggagatgaa gcacctaatc acttctcata
    41881 cacttcacgt gatgaggatt atgtcaagga ccaagtacca tgctggttga cctacaccaa
    41941 tggtaccagt catgagatta tccaaaacaa cctccaccgt gcgcctatgt ttacaggtgt
    42001 ggtcaaggga gtggggcctc gttactgtcc gtcgattgaa gacaagattg tgcgctttgc
    42061 ggacaaggaa cgtcaccaac tcttccttga gccagaaggg cgcaatactg aggaagtcta
    42121 tgttcaagga ctttcaacca gtctgcctga ggatgtccag cgtgacttgg ttcattccat
    42181 caaaggtttg gaaaatgcag agatgatgcg gacaggttat gctattgagt atgatatggt
    42241 cttgcctcat cagttgcgtg cgactttgga aaccaagaaa atctcaggtc tcttcactgc
    42301 tggtcagaca aatggaacat caggttatga agaagctgct ggccaaggga ttatcgcggg
    42361 tatcaatgcg gctctgaaaa tccaaggcaa gcctgagttg attttgaagc gcagtgacgg
    42421 ttatatcggg gtgatgatcg acgacttggt gaccaaggga accattgaac cctaccgtct
    42481 cttgacaagt cgtgctgaat accgtctcat tcttcgtcat gacaatgctg atatgcgctt
    42541 gactgagatg ggacgcgaga ttggccttgt ggatgatgaa cgctgggcta gttttgaaat
    42601 caagaaaaat caatttgata atgagatgaa acgcctagac agtatcaaac tcaagccagt
    42661 caaggaaacc aatgctaagg ttgaggaaat gggcttcaag ccgttgacag atgcggtgac
    42721 agccaaggaa ttccttcgcc gtccagaagt ttcttaccaa gatgtggtgg ccttcatcgg
    42781 accagctgca gaagacttgg atgacaagat tatcgaattg attgaaacag aaatcaagta
    42841 cgaaggctat atttccaaag ccatggatca ggttgccaag atgaaacgta tggaagaaaa
    42901 acgcattcca gccaatatcg actgggatga catcgattct attgcgacgg aagctcgtca
    42961 gaagttcaaa ctcatcaatc cagaaaccat cggccaagcc agccgtattt cgggagtaaa
    43021 cccagcagat atttctattt tgatggtgta tctggaaggt aaaaatcgta gtatttctaa
    43081 aactcttcaa aaatcaaaat gatacgtcgt cggcttctta cgaatgagtt caaagcttgg
    43141 ctttgattca tctccaacct cccatagttc cccgaactat gggagctaac tcaagttatg
    43201 cattttccta gccttctggt ctgattttca ttgagtttta atctcaaaag aaagcataga
    43261 gaaaaacagc tccgaagacg gggctgtttt cttgctttat tcttcatctg gtgtgaggat
    43321 catcgggatg atgatcggtt cacgttcggt attttcatag aggaaggggc gaatagcgtt
    43381 gacaatggca ccattgacag attgcacgct agcatcctta tttttcagtg cgatacgaat
    43441 ggcattgaag aggatacgct ggctttggcg aatcaagtcg ccagactctc tcatgtagac
    43501 aaagcctcgg ctgaggatgt ctggaccaga tagaatcatc tgcgatttga agtcaacagt
    43561 tgcgactgcc agaacgacac cgtcttcaga tagatcgcga cgatctttga ggacagctgc
    43621 gccaatttca ccgatacgat ttccatcgac atagatatct tgggcgttga aatgacctgc
    43681 gatacgagct gagtcagcag taagggcaag cacatcgcca ttgctcatga taaagatatt
    43741 gtccttctca acaccagtat ccactgctag tccagcgtgg actttttgca tgcggtattc
    43801 accgtggaca ggcatgaagt attttggctt aatcaagcag agcatgagtt tttgctcttg
    43861 ctgaccaccg tgtccagatg tatggatatt gttcacttta ccgtggataa cttcgacacc
    43921 agcttcagaa atgatgttaa tcagcttgtt gacgctagta gtgtttccag ggatgggact
    43981 agaagagaag ataacggtat cacctggttg taattgtact tgacggtggg ttccgttggc
    44041 gatacgagag agggctgcca taggctcacc ctgactacct gtacagagga taagaacttc
    44101 tcctgcagga taatctttga tttcatttgg ctcgataaag gttcccttag gagctttgat
    44161 gtagccaaga tcgattccgt tgacaatggc cttttccata gaacgaccaa agaccgcaat
    44221 cttgcgtcca gtcttaacag cagcttctgt tgcctgctgg agacggaaga tatttgaggc
    44281 aaaggatgca aagatgatac gtccttcaat accttggata atcttcataa tggactgacc
    44341 aacgactttt tcagagttgg taaaggttgg tacttccgca tttgtcgagt cagacaggag
    44401 acagagcacg ccttcttcac caagcgcagc catacgatgc aagtccgcag gttctccaac
    44461 tggagtaaag tcgaacttaa agtcacccgt acagacgatt ttcccttgag gagtatgaat
    44521 gacaatcccc aaaggctctg gaatagagtg agtcgttcta aagaaagttg ccttgagatt
    44581 tttaaaggtc aactcggtgt tgtggttgat ttcgtaaagt ttggcgttgc gcaagaggcc
    44641 gtgttcttcg agtttcccac ggatcaaagc caaggcaagc ggtccagcat aaatagggac
    44701 atttgcttgc ttgagtagga acggaatccc accaatgtgg tcctcgtgtc cgtgtgtgat
    44761 taaaacagcc ttgacgcggt cgatattgtc tacgatgtaa gagtagtcag gaatgacata
    44821 gtcgatacca agcaagtcat cttctgggaa tttaatccca gcatcgacga tgataatctc
    44881 gtcttggtat tcaattccgt aagtgttttt cccgatttct cctagaccac cgatggcaaa
    44941 aacgccgact tcttcaggtt taagagtgta ggccatatta gaactccgtg atttcgaagg
    45001 cgccagtttc tttttcgtaa tcgagcaatt tgtcagacaa gagttcgata tattcgatat
    45061 tgtactctgg gcgattttct tcgacaagtt ggcgagcagt gatgcgaccc tcaagttctg
    45121 agctggcatc gatgtctagg taaagcgcgc gtgttgtttc acggcgtggg ctacgttctt
    45181 ttgtttcttg ataaaaaact ttgtaaatca tatagttcct ttctatttac aggtcagctt
    45241 attccaaact tttagcagat atttgcttga tttcattcca ttttgtgtct agattgacct
    45301 tgattcgtta caattatttc aattatacca caaaatgaaa aattagtaaa agacggaaac
    45361 gagaaagtta gggggcgatt tctttggtaa gcgtttgcaa aaataaagaa aatgtgttat
    45421 gttgataacg gaagtgaagt ttattacttg tcataattcc atatagattt taagtcaagg
    45481 aggttgccct atgtataact tatttgcttt tgctatcgga gttcgtttgc tagcttttat
    45541 cgtttttgtt gcttgcgttt atggaggaaa tcttctattt gccaaactgg aacgatgaca
    45601 aaccaagttc ttgtggaaaa ttacctttgt gactctctac tcgctttttc tcctcctcgt
    45661 gacctatgtc gtttggtttg tattttactt tggattaaat gcttagatgc cctgcttatg
    45721 ctggtttttt ttgtttggga atgtagagat agtagattta cgacacgaaa attccacccc
    45781 atctatcaag atgaggtggt ctttgcattt ttctaacatg acatgacaat ggaattttca
    45841 aagcttatta tttttatggg agtcattgtt ctactcaaaa atagagttga agcataaaaa
    45901 taaaacaata caaacagata aatcgaatgg taaagggatg gtagtaatgt tcaaatcatt
    45961 gagaatgctg agcaaactgt aagagatgaa gacaataaaa tttatccttc taaaaatgtg
    46021 tttcttatct agcatgactt accaaacttt ttacgaaggt cttttccaat ggtataacct
    46081 gccataaata aagcgatacc aacaccgaca ccaaagccac ccttgatttc ttgcaattcc
    46141 ttattagaaa tttcacgata attgttcaaa tctttcatca tattaatctc ctcctaaaaa
    46201 ataaccagct gccaaaccag aacctataag tgctgttcca cctgcaatag ccttccaaga
    46261 tactgctact ccaaagataa ccaagggagc gagaccgcca tcaatatctg ataattcatt
    46321 ttcagataag gataaaaatt gattgtcaag aatgtcaaaa tttgtcattg aactttcctc
    46381 cttttttctt gttcactttt atattcggaa aagaaaagga aaagtgagca tttttttaaa
    46441 ttatttttag ttaagtgagg gcactcttgt ctgggggcaa agaaaattcc catgtgccag
    46501 cttttgtagt ataatagtaa gcagacaaaa agataggaat gtgttatgaa agtattagct
    46561 tttgatacgt ccagcaaggc tctttctctg gctattttag aggataagca ggttcttgcc
    46621 gagacgacga ttaatattaa gaaaaatcac agtattactc ttatgcctgc catcgatttt
    46681 ttgatggcaa gtttggattg gacacccaag gatttggacc gaatcgtggt agctgaaggg
    46741 ccgggtagct atacaggctt gcgaattgcg gtagcaactg ctaagacctt agcttacacc
    46801 ctgaacattg agttggttgg tatgtctagt ctcttggctc tagtgccata tcaacaagaa
    46861 ggtttgtttg ttcctttgat ggatgcgcgt cgcaataatg tttatgcagg attttatgaa
    46921 aatgccaaac ctgtcatggc agaagcacat ctgccttttg agcgagtcat tgagctaatc
    46981 aagggcgcta gtcaggtaac ctttgtcgga gaagttggcc cctttgttga gcagattcaa
    47041 aaacacttgc caaggactga ttacaaagaa acattgccca atgcagctaa tctagctctt
    47101 ttggcctggg acaaggaagc agactccttg catgattttg tgccaaatta cctcaaacgt
    47161 gttgaggcag aggaaaactg gctcaagaac cataccgagt ctggtgagtc ttacattaaa
    47221 cgcctatgat agaaatcaaa cgtatccaac agcaacctgc cttggctcaa gatatctacg
    47281 ctgtcatggc agctgtttac ccagtcagtc cttggacact agaacaaatc caagcagatc
    47341 tgtcccaaga ccagacttgg tatgctctgg cctatgatgg ggcagaagtg attggctttc
    47401 taactgttca ggagactctc tttgaagcag aagtcctgca aatcgctgtc aaaggagcct
    47461 gtcagggtca gggaattgcg tcagccttgt ttgctcaatt gccgacagac aaggaaattt
    47521 tcctcgaagt tagacagtca aatcaacgag cgcaagcatt ttacaagaaa gaaaaaatgg
    47581 cggtcatcgc tgagcgaaaa gcctactacc atgacccagt cgaggacgcc attatcatga
    47641 agagagaaat agatgaagga tagatatatt ttagcatttg agacatcctg tgatgagacc
    47701 agtgttgccg tcttgaaaaa cgacgatgag ctcttgtcca atgtcattgc tagtcaaatt
    47761 gagagtcaca aacgttttgg gggcgtagtg ccagaagtag ccagtcgtca ccatgtcgag
    47821 gtcattacag cctgtatcga ggaggcgcta gcagaagcag ggattacaga agaggacgtg
    47881 acagctgtgg cggttaccta tggaccgggc ttggtcggag ccttactagt tggtttgtca
    47941 gctgccaagg cctttgcttg ggcacatgga cttccgctga ttcccgttaa ccacatggct
    48001 ggccatctca tggcggctca aagtgtggaa cctttggagt ttcccttgct agccctcttg
    48061 gttagcggtg ggcacacaga gttggtttat gtttcggagg caggagatta taagattgtt
    48121 ggggaaaccc gtgatgatgc ggttggtgag gcttatgata aggtcggccg tgtcatgggc
    48181 ttgacctatc ctgcaggtcg tgagattgac gagctggctc atcaggggca ggatatttat
    48241 gatttccccc gtgccatgat taaggaagat aatctggagt tctccttctc aggtttgaaa
    48301 tctgccttta tcaatcttta tcacaatgcc gagcaaaagg gagaaagcct gtctacagaa
    48361 gatttgtgtg cttccttcca agcagcagtt atggacattc tcatggcaaa aaccaagaag
    48421 gctttggaga aatatcctgt taaaaccctg gttgtggcag gtggtgtggc agccaataaa
    48481 ggtctcagag aacgcctagc agccgaaatc acagatgtca aggttatcat cccccctctg
    48541 cgactctgcg gagacaatgc aggtatgatt gcctatgcca gcgtcagcga gtggaacaaa
    48601 gaaaacttcg caggctggga cctcaatgcc aaaccaagtc ttgcctttga taccatggaa
    48661 taaagagtgg ctctttgtca agtgtagtgg gtaggcgaaa agctacaatc tggagagtac
    48721 gaaattcgta ctctcttttt tgatgttcaa agtcatcaaa atccgttttt taaaattgtt
    48781 aaagttccgg aaaccaaagg ctttgcgctt gataatctta atcaaattat tggtcgcttc
    48841 aagtttagcg ttggaataag gcagcttaag tgcgttgata atcttatctc tatcccttaa
    48901 aaaagtccaa aagaccgttt gaaaaagcgg atgaaccgtt ggcagttctt gctcaatcaa
    48961 tccaaagaaa tggtcggcat tcttctcttg aaaatgaaag agcaggagtt gatagagttc
    49021 gtagtgaacc tgtaatccct cagagtaaga aagcagctta tctcgtactt cccgatgggt
    49081 taagtgcatt cgaaacgtgg gctgatagaa tcgtttctga cagagcttga agctatactg
    49141 gtgtagtaaa tcagtccagt ggactgattt agcccgagcc tagaaacgaa aaagcgaggg
    49201 ttccaaaagc gcttgagcgc ccgatactcc aaggattttc ggtcaaattg gttcatgatt
    49261 tggattcgta ctcggttcat agctcggctc agatgttgga caatgtggaa gcggtcaaga
    49321 acaatcttcg cctttggaaa gagttgctta gcgagccgat aataagggct gtacatgtcc
    49381 atggtgatga cctcgaccag ctcccgaacc tctctctgat agcgttggaa atggtttcga
    49441 atcaccgcat gagttcgccc gtctaaaatt gcgaggatgg atttggactc aaaatcttgg
    49501 gcaatgaagc tcattttgct ctttttgaag ctatactcat cccaactcat aacttttggc
    49561 aacttggtcc aatcggtttc aaacttaaat tccctcagtt ttcggatgac ggtggaagtt
    49621 gagaccgcca atctgtgggc aatctcagtc atagactgct tttcaaggag gagctgagcg
    49681 attttttgtc tcaccatgtt ggaaatctgg caatttttct tgacaatgga tgtttgagaa
    49741 acgaccacct taaggcaatt cttgcactga aagcggcgct ttttgagatg cagtaccgtg
    49801 ggtaaaccct gacagtcgag aagcggaatt ttagaggctt tctggaagtc gtatttgatc
    49861 atcttccctt gacaatgagg acaaggagga gcgggggaat ccaactttgc ctgaacgact
    49921 agatgggttt ggtatttcag aacagacaag attttgatat ttttgtcttc caatccgagc
    49981 aaatctgtgg tattcttaag ttgttccata tgaacccttt ctaatgagtt ggttagacgc
    50041 ttttcattat aggtcatatg gggctttttt tctacaagaa acgaccctat aattcctggg
    50101 gtgggattac ccactacaga aattatagag ccaaagcatt ccaaagtctt gtctgactct
    50161 ggaatgtttt ctgttcacag ttgttttgta actgcctaat aagtaaccgc gctataacga
    50221 ggtatctacc gagattgtca attctccagt atactgttat aaaaaacaaa actggaggat
    50281 ttttttatgt ccccccatcg tcccatcgac tgttccgtag ctgcccaata acggagtata
    50341 gtcggctgaa acaagaatag gacaaaagtg cctcaagaaa agcatcgtaa tttgacaata
    50401 ttattctgag atgtttttga tgtaagccca tattttctca atgggattat actcgggtga
    50461 ataggtagga agtggtaaca gtctatgccc tgctccttac acatgttcat tctgtgaaac
    50521 cttgcatggt ccataatgat aagggatggt gtatctaaag taggtagtaa gaatttttgg
    50581 aagcaagctt cgaaaaagtc actcgtcatc gtatctttat aggtcatcgg agccatagta
    50641 tattgaaaca aaaaagggca ttagtacttc tataacagta tcgcaatctc tggtgtgcgt
    50701 tgtctcgatc ttaattcaaa taattatatc ttcttccaga gagactaact gcctgctcaa
    50761 ggctcgatca tattcgagat aaaaataggt ctcaacccct gtctcataaa tataaatagg
    50821 agtcaggtag cttaagtgat tcaattcttt aaggaaccga tttacttttt ctgggtcttg
    50881 ttcgcagtag gtacggctct tttttagact atatcccata gcctttagag cgtaatgaat
    50941 agttgttgga ggacagttga attcagcagc tatttcagtc aaataagcat cgggatgagt
    51001 ttcaatatag atttttaatt tatctctatc aattttttca attaatagtg gaagttttct
    51061 tgaagttagt gtattgaaac gtttttatac agtgctaaaa tttgaagtgt agtgcagatg
    51121 gatttgtaat agtattatag caattctttg gagaaggtcg agacaagata aaataggtat
    51181 ctttgagata taagcatgat ttactataaa attattgagt tattcataaa aatttctcta
    51241 tcaaatatca taatgcgtcg tttaaggaga tggttacaat gcaatatagt tgtggaaaaa
    51301 taaatattaa tatccctgat ggatatggag acattaagga tatagtgttt tcggctcata
    51361 ttatagttag gtataataat ggacattgtg gaggtataga tccgcatata attggacttt
    51421 gtaaaaagca gatcagaagg atgtctctat atcctatttt gataatcgta tctagagatt
    51481 caaaggttat tgatgattat aaaaatttag atattgccta tgttgattgt actcaatgtt
    51541 caaataattt tgaaactgcc ttacacgtta aaaatatttt aaaattatta aaaatccaac
    51601 ttatacactg tcatggctac tcaactaatt attttttata tatgttaaaa aaacttgaca
    51661 agaatggatt tggaaaggtt aagacagtga taacatgcca tggatgggtt gaatataact
    51721 taaaaaagaa attcttgact tattttgatt tttggacata ttctatggga gatgctttta
    51781 tttgtgtatc tgaaactatg aaaaaaagat tggagagtat aataaaaaaa taagaagata
    51841 gttgcaataa ataacggaat taatgtatca aatagcgatt tagatgtagt aggtgttcaa
    51901 gactttaaaa aagaattttg tattccaaat aacaaaaaaa tcatttgtta tgttggaagg
    51961 ttggatccag aaaaaaggcc ggatagattc cttgaatttg cagaaaaatt atttttagtc
    52021 agagaagatg tgatttttat tatggctgga aatggtagta tgtgggctgc tttgaaagaa
    52081 aaaatttgcc atttgaaatg tagagataat ttcaggttac ttggtgaaat ctatccagct
    52141 actatagttt accaaatatc ggatttattg tatatttctt ctgatacaga aggaatacct
    52201 atgtgtgttt tagagtcaat gtcacaagga acttcggttt tagctagtaa tgttggcggg
    52261 ttaagtgaaa ttattgaaca tagggttgat ggatttttat ttgagaagga agatgttgag
    52321 ggagtgtgtg cttgtgctaa ttttttactc aatgattctg agtatttgaa atatataggt
    52381 gagaatagta aatcaaaaat aagaaaacat ttttctgtgc aaaaaatgtt tgtagaaacc
    52441 atgagagtat atgatgaatt attagagaag agtagtcatg gataggaata tagatcaaga
    52501 attagtaagt attataatac caacacataa taggtatgaa tctctgatta gagctgtgaa
    52561 aacttgttta catcaaagtt ataaaaatat cgaagttata attattgatg ataattatag
    52621 taatgtaaat ttaagaaata aaattatcca tcaatttggc tataccaatc atagaattaa
    52681 gttaatttta agtaatgaag atttaggtgc aactaatgcc agaaacatag gtatcaaaaa
    52741 ttctagaggt aagtatatat catttttaga cgatgatgat gaatatatgc cagatcgaat
    52801 tttaaagttg atggcttgtt ttaaaaagag tagaatgaag aatttagctt tagtttatag
    52861 ttatggaata ataatttatc caaatggtac acgagaagag gagaagaccg attttgttgg
    52921 aaatcccttg tttgttcaaa tggttcacat caggacggtg ttgttttatt aaaactactt
    52981 gctcaaggat accaaattga tatagtgcga gaattcttgg tgaattacta cgctcacagt
    53041 aaagaaaacg gtatcactgg agtgacacaa aaaacaatta atgcagatga agaatattat
    53101 aattactgta ggaaatattt taatttattg agtttcaacg agagaatatt ggttacaaag
    53161 aaatattatt ctttaaacat aaagcggtta ctattaatag gagacaaatg caaggcttta
    53221 aaagtaatca agaaggcaag agaagaaaaa atttttaacg aatttctttt ttgaaatata
    53281 tgttattata tcattttggt tttttctatt gtatatatga caactatgtt caattaaaat
    53341 ttagaaagtg agaaactatt gtgtatacta ttataaaatc aaatataaaa aaatttagtt
    53401 tattaacgat atttattgtt gctggtcaat tattgctaat ttatgcagca actattaatg
    53461 ctctggtgtt gaatgaatta attgcgatga atttagagcg gtttttgaaa ttgtcaatct
    53521 accaaatgat tgtctggtgt gggataatat tccttgactg ggtagtgaaa aattatcagg
    53581 ttgaagtgat ccaagagttt aatctagaga ttcgaaatag aattgccaca gacatctcta
    53641 actctaccta tcaagaattt catagtaaat catcaggaac atatctttcg tggctaaata
    53701 atgatgttca gactttaaat gatcaggctt ttaaacaact ttttttagta ataaaaggaa
    53761 tttctggtac tatatttgca gttgtgactc ttaatcacta tcattggtca ttgactgtag
    53821 ccaccttgtt ttcattaatg attatgctac ttgtaccaaa aatctttgca tcgaaaatgc
    53881 gagaagttag tctaaattta actaaccaaa atgaagcttt tttaaaatct agtgagacta
    53941 tattgaatgg atttgatgtg ttagcgtcct tgaatctttt atatgtattg cctaagaaaa
    54001 ttaaagaagc aggaatttta ttaaagatgg ttatacaaag aaagacaact gtagaaacgt
    54061 tagcaggcgc tattagcttc tttctcaata ttttttttca gatatctctc gtttttttaa
    54121 caggctatct tgcaataaaa ggaatagtga aaattggtac tattgaagca ataggagcac
    54181 taacaggtgt tatttttaca gcgctaggtg aattaggagg tcaattatcc tctattattg
    54241 gtacgaagcc tattttttta aaattgtatt caattaatcc aattgagtca aataaaatga
    54301 atgatatcga accaaatgag gtgaatagag attttccgtt atatgaagca aaaaatattt
    54361 gctataagta tggagataaa gaaatattaa aaaacttaaa tttttgtttt caacgtaatg
    54421 aaaagtattt aattttaggt gaaagtggaa gcgggaaatc tacattatta aaattattga
    54481 atggcttttt gagagattat agtggagaat tgcgattctg cggggatgat ataaaaaaaa
    54541 cctcctattt aaatatggtt tcgaatgttc tatatgtaga tcaaaaagct tatttgtttg
    54601 aaggtacgat tagagataat attttattgg aagaaaatta tactgatgaa gaaatactac
    54661 agtctttaga gcaagttggt ttgagtgtaa aagattttcc taataacatt ttagattatt
    54721 atgttggtga tgatgggaga ttactgtcag gagggcagaa acaaaaaatt actttagcta
    54781 gagggctaat tagaaataag aaaatagtat taattgacga gggaacttct gctatcgata
    54841 ggagaacttc gttagcgatt gaacgtaaga tattagatag agaggatttg actgtcatta
    54901 ttgttaccca tgctccgcat ccggaactta aacaatattt tactaagata tatcaatttc
    54961 caaaggattt tatttaagaa tataggggag ggaaacatga gattctattg tgaagcttat
    55021 gaggtaatta ctgaagagaa aaaagtatac tttaatgata ttgagttaga agttaagtat
    55081 tcctctgtcg aagaattgtt tataatatgt gagaaattat tagataagaa aaaagtatca
    55141 tttttttatg tagatgagaa acccttaagg tatctgttat ttgactatat atttccacta
    55201 gttctagcta aaaaaaaata tcccaatctt agatggagtt tccaataagc aagttgctcc
    55261 aacgttgctg catcactttt ctttggaaat tgaaaagaat tttatcgatt tttgctataa
    55321 aaatatggat ctcatcctaa aaactcaaag tatatctttg tgtcatagag aagagcttat
    55381 tattgtagat gtttcagatg actctaaatt tggtgttttt tacaagcgtt ttagaacact
    55441 ggttgataaa aataacggaa aatatgtttg tgtttataat ttcagtcgtg tttcagatat
    55501 actgcaaaac tggaaaaatt attgcaatcg aaaattttcg gttacgttta ctgaaagcca
    55561 atttgaatta tttaagcttt tatataatca aaaaaatttt aaaacaattt cgttgctatt
    55621 tggaaaaaaa ttgttgctgg aggaattatc tattatagcg atcttactaa tatagaatac
    55681 ttttgtattt tttggtggga tagtatgttt gggaaagatt ctattggaaa atacgtatat
    55741 gtagaagaga ttagtagatg tcatttttta gatagaaatt attctttttg ttatggttta
    55801 caagattata aaagtaaact tattaaatat tttttagaat agttaatcta ttcgagagag
    55861 ataaagaaat atggaaaata ctttattgaa tatcacagga agcttcgata tggaaactag
    55921 gaatctaatt agttattctt taactgatat ctttgaaaca gataaaataa gaattgaact
    55981 tcttggagaa atttattata aaaatataaa gttggaattg catgaattcg ctggattgta
    56041 taagatttat ggaattagct taataaagaa tattaccgga atgtttttaa ttataatttt
    56101 tgatacgaag acaaaagaat taaaaatttt tcaagatata acgacttcat actttaattt
    56161 atactatact gtttatggag gtgtgttcta tatatagtac atctttaaag aaagtgatga
    56221 agttatctca tgttcccgtt accttaaata acaaaaaaat acaagaattt atgagaaatg
    56281 gatttatttt agattcaaat actttagtaa ccgaaattaa taaattagaa tatttctctt
    56341 acatttctgt aaataatact attcgtatat gtggtattga ttataatgat tcaaacaatt
    56401 ttactaaaga acaagtatta aagaattggg actctatgct acgtgaatct atattaagag
    56461 tgtatagtga agcaggagag gctaatatta cactatcatc tggttttgat tcaaattata
    56521 tattatatac attagcgaat tatacgaatt cttcaattaa tgcattttgc ataggaggag
    56581 aaaaaggaat taatgagatt cctgaagtaa ctaaaattgc aaaattttat ggtataaatt
    56641 tattagttga tactgtaatg agccaagatt tagaatccca
//
LOCUS       DAVHKZ010000008        54511 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000008 DAVHKZ010000000
VERSION     DAVHKZ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54511
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.008"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(16..657)
                     /gene="plsY"
                     /locus_tag="VVO74_000637"
     CDS             complement(16..657)
                     /gene="plsY"
                     /locus_tag="VVO74_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU5694701.1"
                     /translation="MITIILLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            793..2736
                     /gene="parE"
                     /locus_tag="VVO74_000638"
     CDS             793..2736
                     /gene="parE"
                     /locus_tag="VVO74_000638"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU5694702.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KVGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3156..5627
                     /gene="parC"
                     /locus_tag="VVO74_000639"
     CDS             3156..5627
                     /gene="parC"
                     /locus_tag="VVO74_000639"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU5694703.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLRIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKNFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            5757..6779
                     /locus_tag="VVO74_000640"
     CDS             5757..6779
                     /locus_tag="VVO74_000640"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU5694704.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            6835..7539
                     /locus_tag="VVO74_000641"
     CDS             6835..7539
                     /locus_tag="VVO74_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5694705.1"
                     /translation="MVLSTLAILVACGKTDKEADAPTTFSYVYAVDPASLGYSITTRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPIVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            7604..8293
                     /locus_tag="VVO74_000642"
     CDS             7604..8293
                     /locus_tag="VVO74_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU5694706.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8290..9213
                     /locus_tag="VVO74_000643"
     CDS             8290..9213
                     /locus_tag="VVO74_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU5694707.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9228..9872
                     /gene="pcp"
                     /locus_tag="VVO74_000644"
     CDS             9228..9872
                     /gene="pcp"
                     /locus_tag="VVO74_000644"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU5694708.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10040..10270
                     /locus_tag="VVO74_000645"
     CDS             10040..10270
                     /locus_tag="VVO74_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU5694709.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10320..10400
                     /locus_tag="VVO74_000646"
     tRNA            10320..10400
                     /locus_tag="VVO74_000646"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10354..10356,aa:Tyr,seq:gta)
     gene            10410..10481
                     /locus_tag="VVO74_000647"
     tRNA            10410..10481
                     /locus_tag="VVO74_000647"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10442..10444,aa:Gln,seq:ttg)
     gene            10643..11845
                     /gene="rpsA"
                     /locus_tag="VVO74_000648"
     CDS             10643..11845
                     /gene="rpsA"
                     /locus_tag="VVO74_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU5694710.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRVARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(11931..12299)
                     /locus_tag="VVO74_000649"
                     /pseudo
     CDS             complement(11931..12299)
                     /locus_tag="VVO74_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            12547..13044
                     /locus_tag="VVO74_000650"
     CDS             12547..13044
                     /locus_tag="VVO74_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU5694711.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            13044..14699
                     /gene="dnaX"
                     /locus_tag="VVO74_000651"
     CDS             13044..14699
                     /gene="dnaX"
                     /locus_tag="VVO74_000651"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU5694712.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            14727..14921
                     /locus_tag="VVO74_000652"
     CDS             14727..14921
                     /locus_tag="VVO74_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU5694713.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            15071..15841
                     /gene="sufC"
                     /locus_tag="VVO74_000653"
     CDS             15071..15841
                     /gene="sufC"
                     /locus_tag="VVO74_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU5694714.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            15869..17131
                     /gene="sufD"
                     /locus_tag="VVO74_000654"
     CDS             15869..17131
                     /gene="sufD"
                     /locus_tag="VVO74_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU5694715.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            17142..18368
                     /locus_tag="VVO74_000655"
     CDS             17142..18368
                     /locus_tag="VVO74_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU5694716.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVINPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            18355..18795
                     /locus_tag="VVO74_000656"
     CDS             18355..18795
                     /locus_tag="VVO74_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU5694717.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            18849..20261
                     /gene="sufB"
                     /locus_tag="VVO74_000657"
     CDS             18849..20261
                     /gene="sufB"
                     /locus_tag="VVO74_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU5694718.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(20492..21733)
                     /locus_tag="VVO74_000658"
     CDS             complement(20492..21733)
                     /locus_tag="VVO74_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU5694719.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKTPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            21836..22945
                     /locus_tag="VVO74_000659"
     CDS             21836..22945
                     /locus_tag="VVO74_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU5694720.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            23479..23826
                     /gene="ssrA"
                     /locus_tag="VVO74_000660"
     tmRNA           23479..23826
                     /gene="ssrA"
                     /locus_tag="VVO74_000660"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(23999..24086)
                     /locus_tag="VVO74_000661"
     tRNA            complement(23999..24086)
                     /locus_tag="VVO74_000661"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24050..24052),aa:Ser,seq:gga)
     gene            24249..24989
                     /locus_tag="VVO74_000662"
     CDS             24249..24989
                     /locus_tag="VVO74_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU5694721.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            24986..25897
                     /gene="pfkB"
                     /locus_tag="VVO74_000663"
     CDS             24986..25897
                     /gene="pfkB"
                     /locus_tag="VVO74_000663"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU5694722.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTVEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            25894..27846
                     /locus_tag="VVO74_000664"
     CDS             25894..27846
                     /locus_tag="VVO74_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU5694723.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSAGQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            28010..30235
                     /locus_tag="VVO74_000665"
     CDS             28010..30235
                     /locus_tag="VVO74_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU5694724.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKTLLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(30280..30708)
                     /locus_tag="VVO74_000666"
     CDS             complement(30280..30708)
                     /locus_tag="VVO74_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694725.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITAGITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            30846..31988
                     /locus_tag="VVO74_000667"
     CDS             30846..31988
                     /locus_tag="VVO74_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU5694726.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            31997..33211
                     /gene="thiI"
                     /locus_tag="VVO74_000668"
     CDS             31997..33211
                     /gene="thiI"
                     /locus_tag="VVO74_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU5694727.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGRAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            33346..34169
                     /locus_tag="VVO74_000669"
                     /pseudo
     CDS             33346..34169
                     /locus_tag="VVO74_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            34191..34930
                     /locus_tag="VVO74_000670"
                     /pseudo
     CDS             34191..34930
                     /locus_tag="VVO74_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            34943..36109
                     /locus_tag="VVO74_000671"
     CDS             34943..36109
                     /locus_tag="VVO74_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU5694728.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     ATTFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            36617..38110
                     /locus_tag="VVO74_000672"
     CDS             36617..38110
                     /locus_tag="VVO74_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU5694729.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            38123..39188
                     /locus_tag="VVO74_000673"
                     /pseudo
     CDS             38123..39188
                     /locus_tag="VVO74_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            39248..39484
                     /locus_tag="VVO74_000674"
     CDS             39248..39484
                     /locus_tag="VVO74_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEU5694730.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            39481..39894
                     /locus_tag="VVO74_000675"
     CDS             39481..39894
                     /locus_tag="VVO74_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEU5694731.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            40012..40977
                     /locus_tag="VVO74_000676"
     CDS             40012..40977
                     /locus_tag="VVO74_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU5694732.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            41000..41581
                     /locus_tag="VVO74_000677"
     CDS             41000..41581
                     /locus_tag="VVO74_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU5694733.1"
                     /translation="MFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTK
                     NVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRI
                     NSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQ
                     NEFADFVVQVDKSQFACEIAIKVWRNSLKFSII"
     gene            41611..44961
                     /locus_tag="VVO74_000678"
     CDS             41611..44961
                     /locus_tag="VVO74_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU5694734.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYKKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEQY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            45232..45432
                     /locus_tag="VVO74_000679"
     CDS             45232..45432
                     /locus_tag="VVO74_000679"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694735.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHIYGKATLTRIEEIFEEYKSS"
     gene            complement(45549..46019)
                     /locus_tag="VVO74_000680"
     CDS             complement(45549..46019)
                     /locus_tag="VVO74_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU5694736.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(46036..48309)
                     /locus_tag="VVO74_000681"
     CDS             complement(46036..48309)
                     /locus_tag="VVO74_000681"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU5694737.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQIFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQNKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            48656..51757
                     /locus_tag="VVO74_000682"
     CDS             48656..51757
                     /locus_tag="VVO74_000682"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU5694738.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVSYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRVSFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            51840..52847
                     /gene="pfkA"
                     /locus_tag="VVO74_000683"
     CDS             51840..52847
                     /gene="pfkA"
                     /locus_tag="VVO74_000683"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU5694739.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSADEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            52906..54411
                     /gene="pyk"
                     /locus_tag="VVO74_000684"
     CDS             52906..54411
                     /gene="pyk"
                     /locus_tag="VVO74_000684"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU5694740.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT        16748 a         9647 c        11981 g        16135 t
ORIGIN      
        1 cacagaactg gcattttatt ttttaggatc ttgatgggtt aggttcaatc cccaagggac
       61 caaattttca gttttatttt tgatacgagc tatattgtcc ttatgacgaa tgataatcaa
      121 actagcaagt gctaagataa tagcgatgaa gagagagtca tagttactca ggataaaacc
      181 aaaaagtgga aagagcagaa ccccgataac agccgcgatc gatgctgtga cactagacag
      241 tgaaatcata ctgccaagat agagagctcc aaagaagata atcgcaaggt agagacagaa
      301 gataggcgca aatccgaaaa tcactccagc actggttgcg acagccttac cacctttaaa
      361 tcctgcaaag atagggaagg tatggccgat aacagccaaa agtccaaaga tgagaggaga
      421 aacgccttgt agatgaaaaa taatcggaag cagcgttgct agggttcctt tgaaaaagtc
      481 aatcacaaag gttgccatac cagctttctt acctaaaatg cggaaggtat tggtcgttcc
      541 agtgttacca gaaccatgct cgcgtagatt gatttgaaag aatacttgtc caatccagag
      601 accagatgga atcgaaccca gcagataggc taggattaat aaaattattg taatcatact
      661 cctattatat catgaattgg gaaagaaaag cagagaatct ctgctgaaat tgtcacatcg
      721 gagaaagaaa aattttgcaa aatccttgga aaacctgtag aatagtaaag atgaacgaat
      781 aggaggttcc ttgtgtcaaa aaaggaaatc aatattaaca attataatga tgatgctatt
      841 caggtgctag aagggttgga tgcggtccga aaacgtccag ggatgtatat tggatcgacc
      901 gatggcgctg gtcttcatca cctagtttgg gaaatcgttg ataatgcagt cgatgaagcc
      961 ttgtctgggt ttggtgatcg tattgatgta actatcaata aagacggtag tctaacggtt
     1021 caagaccatg gacgtgggat gccgacaggt atgcacgcta tgggaattcc aactgttgag
     1081 gttatcttta ccattcttca tgccggaggg aaattcggtc aaggtggcta taagacatca
     1141 ggtggacttc acggagtggg ttcttccgtt gttaacgccc tttctagctg gttagaagtt
     1201 gaaattaccc gtgatggcgc agtttacaag caacgttttg aaaatggtgg aaaacctgtc
     1261 acgactttga agaaagtcgg tacagcaccc aagtctaaaa caggcaccaa agttactttt
     1321 atgcctgacg cgactatctt ttctacgaca gatttcaagt acaataccat ttcagagcgc
     1381 cttaatgaat cagcctttct cttgaaaaat gtgaccttgt ctttaacgga caagcgaaca
     1441 gatgaagcga ttgagttcca ctatgagaat ggagtacaag attttgtttc ttatctcaac
     1501 gaagataagg aaatcttgac gccagttctt tactttgaag gggaagacaa tggttttcaa
     1561 gtggaagtag ccctccagta caatgacgga ttctcagata acattctatc ctttgtcaat
     1621 aacgttcgca ccaaggacgg tggaacgcac gagacaggac tcaagtctgc cattaccaag
     1681 gtcatgaatg actatgcacg taaaacaggt cttctcaagg aaaaagataa aaaccttgaa
     1741 ggttcagact atcgtgaggg actagcggcc gttctttcta tcttagttcc tgaagaacac
     1801 ttgcagtttg aaggacagac caaggataaa ctaggaagcc ccctagctcg cccagttgtg
     1861 gatggaatag tggctgataa gttgaccttt ttccttatgg aaaatgggga attagcttct
     1921 aacctcatcc gcaaggctat caaggcccgt gatgctcgtg aagcagcacg taaggcgcgt
     1981 gatgagagcc gaaatgggaa gaaaaacaag aaagataagg gcttgttgtc tgggaaattg
     2041 accccagccc aatctaagaa tcctgctaag aatgaactct atctagttga gggggactct
     2101 gccggtggtt ctgccaaaca aggtcgtgac cgcaagttcc aggctattct acctcttcgt
     2161 ggtaaggtta tcaatacagc caaggccaag atggcggata tcctcaaaaa tgaagagatc
     2221 aataccatga tttataccat tggtgcgggt gttggagcag acttctctat tgaagatgcc
     2281 aactatgata agatcattat catgaccgat gcggataccg acggtgccca tatccagacc
     2341 ttgctcttga catttttcta ccgttacatg cgtccgctag tcgaggcagg tcatgtctat
     2401 attgccctcc cacctcttta caagatgtcc aaaggtaaag gcaagaaaga agaagtggcc
     2461 tacgcttgga cggacggaga actagaagaa ctccgtaaac agttcggtaa aggcgctacc
     2521 ctccaacgat acaaaggact tggtgagatg aatgcggacc agctctggga aacaaccatg
     2581 aacccagaaa cacgtaccct catccgtgtc acaattgaag atttagcgcg cgccgaacgc
     2641 cgcgtcaatg ttctcatggg agataaggta gaaccacgcc gtaaatggat tgaagataat
     2701 gtcaagttta cgctagaaga agcgacagtg ttttaatgaa agaaaataat atgttagtaa
     2761 actggaaatt agagtcggat gtgaatgact atgtgaaaaa gcagtttgaa aatcttggtt
     2821 tgaaaaaatt gcaggattat taatgaagaa tctgctatga gtgcttatct taaagaggcg
     2881 cttaagggag cggttaagac acaaactaag actaattttg gaaaaccaga ttttcatatt
     2941 gaaaaataca aacaggatag tttggttact tatcgtaact gaacacggga cgaattcccg
     3001 taaaatatct tttactgcat aaaaacctac tctacattct ttgaaaggag ttgaacacgc
     3061 cctagatact gtgtgaaaaa gataaattct cttgtgagtt tgcttacttc aagaattttc
     3121 tattttcact tggtatttta tgggctttgt atcttatgtc taacattcaa aacatgtccc
     3181 tggaggacat catgggagag cgctttggtc gctactccaa gtacattatt caagaccggg
     3241 ctttgccaga tattcgtgat gggttgaagc cggttcaacg ccgtattctt tattctatga
     3301 ataaggatag caatactttt gacaagagct accgtaagtc ggccaagtca gtcgggaaca
     3361 tcatggggaa tttccaccca cacggggatt cttctatcta tgatgccatg gttcgtatgt
     3421 cacagaactg gaaaaatcgt gagattctag ttgaaatgca cggtaataac ggttctatgg
     3481 acggagatcc tcctgcggct atgcgttata ctgaggcacg tttgtctgaa attgcaggct
     3541 accttcttca ggatatcgag aaaaagacag ttccttttgc atggaacttt gacgatacgg
     3601 agaaagaacc aacggtcttg ccagcagcct ttccaaacct cttggtcaat ggttcgactg
     3661 ggatttcggc tggttatgcc acagacattc ctccccataa tttagctgag gtcatagatg
     3721 ctgcagttta catgattgac cacccaactg caaagattga taaactcatg gaattcttac
     3781 ctggaccaga cttccctaca ggggctatta ttcagggtcg tgatgaaatc aagaaagcct
     3841 atgagactgg gaaagggcgc gtggttgttc gttccaagac tgaaattgaa aagctaaaag
     3901 gtggtaagga acaaatcgtt attactgaga ttccttatga aatcaataag gccaatctag
     3961 tcaagaaaat cgatgatgtt cgtgttaata acaaggtagc tgggattgct gaggttcgtg
     4021 atgagtctga ccgtgatggt cttcgtatcg ctattgaact taagaaagac gctaatactg
     4081 agcttgttct caactactta tttaagtaca ccgacctaca aatcaactac aactttaata
     4141 tggtggcgat tgacaatttc acacctcgtc aggttgggat tgttccaatc ctgtctagct
     4201 acatcgctca ccgtcgagaa gtgattttgg cgcgttcacg ctttgacaaa gaaaaggctg
     4261 agaaacgtct ccgtatcgtc gaaggtttga ttcgtgtgat ttcgattttg gatgaagtca
     4321 ttgctcttat ccgtgcttct gagaataagg cggacgccaa ggaaaacctc aaagttagct
     4381 atgattttac ggaagaacag gctgaggcta tcgtaacttt gcaactgtac cgtttgacca
     4441 ataccgatgt ggttgtcttg caggaagaag aagcagagct tcgtgagaag attgctatgc
     4501 tggcggctat tatcggtgat gaaaggacta tgtacaatct catgaagaaa gaacttcgtg
     4561 aggtcaagaa gaactttgca actcctcgtt tgagttcttt agaagacact gcgaaagcaa
     4621 ttgagattga tacagctagt cttatcgctg aggaagatac ctacgtcagc gtgaccaagg
     4681 caggttacat caagcgtacc agtccacgtt cctttgcggc ttccaccttg gaagaaattg
     4741 gcaagcgtga tgatgaccgt ttgatttttg ttcaatctgc caagacaacc cagcacctct
     4801 tgatgttcac aagtcttgga aatgtcatct acagaccaat ccatgagttg gcagatattc
     4861 gttggaagga catcggagag catctgagcc aaaccatcac aaactttgaa acgaatgaag
     4921 caatccttta tgtggaagta ctggatcagt ttgacgatgc gacaacctac tttgcagcga
     4981 ctcgccttgg tcaaatcaaa cgggtagagc gaaaagaatt cactccatgg cggacctata
     5041 gatctaagtc tgtcaagtat gctaagctca aagacgatac agatcagatt gtagcagtgg
     5101 ctccgattaa actagatgat gttgtcttgg ttagtcaaaa tggttatgcc ctgcgtttca
     5161 atatcgaaga ggttccggtt gtcggtgcta aggcagcagg tgtcaaggct atgaatttga
     5221 aagaagatga tgtcctccaa tctggcttta tctgtaatac ttcgtccttc tacctcttga
     5281 cccagcgtgg aagcttgaaa cgtgtttcca ttgaggaaat tctagcaacc agccgtgcca
     5341 aacgaggatt acaagtcttg cgtgagttga aaaacaaacc gcatcgtgtc ttcttggcag
     5401 gagcagttgc agagcaagga tttgttggcg atttcttcag tacggaagtg gatgtgaacg
     5461 accaaactct gcttgtccaa tccaataaag gaacaatcta tgaaagccga ttgcaagact
     5521 tgaacttgtc agaacgcact agcaatggaa gcttcatttc tgacacgatt tcagatgaag
     5581 aagtttttga cgcttatctt caggaagtag ttactgaaga taaataagtg aaatgaagaa
     5641 tcagttctaa gatggttttt attggaggaa ttttctgaaa attacaaaat atacttgcta
     5701 ttttagaaaa atagtgtaga atataagaaa taggttttta gaataaggag tggaatatga
     5761 cagtaacgat tgattgggaa aacctcggtt tttcctatat gaaattacct tatcgctatc
     5821 ttgctcattt caaaaatgga caatgggatc aaggagagct tacagaggat gcaactttgc
     5881 atatttcaga gtcttctcca agtcttcact atggacaaca agcatttgaa ggtttgaaag
     5941 cttatcgtac taaggatggc agtgttcaac tgttccgtcc tgatgaaaat gctaaacgcc
     6001 tgcaacgtac atgtgaccgt ctcttgatgc cacaagttcc gacagacatg tttgtagaag
     6061 cttgtaaagc agttgtccgt gcgaatgaag aatacgtacc accatacgga ataggtggaa
     6121 ccttatatct tcgccctctt ttgattggtg tcggagatat tatcggggta aaaccggcag
     6181 aagagtacat tttcaccatc tttgctatgc cagttggaaa ttactttaaa ggtggtttgg
     6241 tcccaaccaa cttcttgatt caggatgagt acgaccgtgc agcaccaaat ggtacaggtg
     6301 cggctaaggt tggtggaaac tatgctgcaa gtctcttacc aggaaaaatg gccaagtcac
     6361 gccatttctc agatgttatc tatctggacc catcaactca tacaaagatt gaagaagtcg
     6421 gatcagctaa tttctttgga attacagctg ataatgaatt tgtaacacca ttgagtccat
     6481 ctatcttgcc atctattacc aagtattcct tgctttattt ggcagaacat cgcttgggat
     6541 taactcctat tgagggtgat gttccaattg ataatcttga ccgttttgta gaggcaggtg
     6601 cctgtggtac agcagcggtt atttctccaa ttggaggtat tcaacatggt gatgatttcc
     6661 atgtattcta tagtgaaaca gaagtaggtc ctgtgacgcg taaattatat aatgaattga
     6721 cgggtattca gtttggcgat attgaagcgc cagaaggttg gattgtaaaa gtagattaaa
     6781 ataaaccaaa ggagattttt tatgaaatag aaaaagtggc tcttaacagc aggagtggtc
     6841 ctgagcacgt tagctatttt agtggcttgt ggaaaaactg ataaagaagc agatgcaccg
     6901 acaacatttt cttatgtcta tgcagtagat ccagcatcat tgggctacag tataacgact
     6961 cgaacatcga cgacagacgt tattggaaat gttattgatg gtttgatgga aaatgataaa
     7021 tacggcaatg ttgctccttc tcaaaaagac tatgatttga atagtacagg atgggctcca
     7081 agctatcaag atccagcgtc ttacttgaat attatggatc caaaatctgg ttctgccatg
     7141 aaacaccttg gtattacgaa aggaaaagat aaggatgttg tagctaaacc tggtttggat
     7201 aaatataaga aattgttaga agatgctgtt tctgagacca ctgacctaga gaagagatat
     7261 gaaaaatatg ccaaagctca agcttggtcg acagatagtt cattattgat gccaacagct
     7321 tcatctggtg gttctccaat tgtaagtaac gtagtaccat tctcaaaacc atactcacaa
     7381 gttggtatta agggggaacc atatatcttt aaaggaatga aattgcaaaa agatattgtt
     7441 acaacaaaag aatataacga ggtttttaaa aaatggcaaa aagaaaaatt ggaatccaat
     7501 agcaaatacc aaaaagaact agaaaaacac attaaataag gaatggtatt gatcttgata
     7561 aaatttttaa aatactgtca ttttgaatat aaaggagttt gatatggagt ggattagatt
     7621 aataggaata gcaatcattg ttgtgggttt tattttaaaa tttgatacaa ttgcaacagt
     7681 agtcttagct ggtttggtta cagctttagt ttcaggtgtt tctctcgttg aatttttgga
     7741 gattttggga aaagaattta gcaatcagcg agtgctcacg atttttatgg ttaccttgcc
     7801 tcttgtgggg ctgtcagaaa cctttggact caagcaacga tcaatcgatt tgattcgaaa
     7861 gattaaaggt ctgacagttg gaaacttcta tacagtttat ttctttattc gagagttagc
     7921 tggtttcttt tcaattcgtc taggaggaca ccctcagttt gtcagacctt tggttcaacc
     7981 tatgggagaa gcagctgcag agtctcaatt aggtagaaag ttaacagagg ttgaagatga
     8041 gacaataaaa gcgcgtgcgg ctgcgaatga aaattttgga aatttctttg ctcaaaatac
     8101 gtttgtaggt gctgggggag tcctcttgat agggggaaca ttagatcagt taggctatga
     8161 aagcaattat gcagggattg cttctacatc tattattgtt gctgttataa cacttattgt
     8221 agtggggatt tacaattatt tatttgataa aaaattgata tcaaaaaaga ctaggggagg
     8281 agaacaaaaa tgacagagtt ggcaaagcaa ctattagagt tgacctatat tgtgattggt
     8341 tgtcaatttc tccatacagc ctattgtagt tataaagata aaacaaaccc agttcgactt
     8401 gggacatctg cattttggac tctattgtct attacgttta taggtggttc ctatatgcca
     8461 aatatgagta ttggtattat tgtaatccta ttatcgctgt taacattgtt taagcaagtc
     8521 cgtatcggaa ccttgccatc cttagatgaa atgaaagcca atattgaatc taacaggttg
     8581 aaaaataaaa tttttattcc agttatgctg atggcaatac ttgcgttggt cttagcgcaa
     8641 atgattccag aatttagcaa gatttcgatt agccttgccg ccttgtttgc tacaatttct
     8701 gttcttgtga ttaccaatag tcaccctaag agtctgttat cagaaaataa tcgaatgact
     8761 cagcaagttt caacaagtgg gattgttcct caattattag gggctttggg ggctattttt
     8821 actgtagcag gtgttggtga tgttatctct catctgatta gcggtattgt tccttcagat
     8881 agtcgcttta taggagtttt ggcctatgtt cttggaatgg ttctattcac aatgattatg
     8941 ggaaatgctt ttgcagcatt caccgttatt acagcaggtg ttggagttcc cttcgtattt
     9001 gctctgggag ctaatccaat tgtggctggt gctcttgcca tgacagcagg ttattgtggg
     9061 accttattga ccccaatggc tgctaatttt aacgctctac cagcagcatt gatggatatg
     9121 aaagatcaga atggcgttat aaaggctcaa gcaggtgttg ctctagtaat gattgttatt
     9181 cacatattct taatgtactt tctcgcattt tagtaaagga aaataaaatg aaaatattgg
     9241 ttacaggttt taatcctttt ggaggtgaaa agattaatcc agctttggag gctgtaaaat
     9301 tattaccatc tgagattaat ggggctgaag ttcgctgggt agaaattcca acggtttttt
     9361 ataagtcgtc agaagtttta gaggcagaaa tattacgata tcaaccagat gctgtacttt
     9421 gtattggaca agcaggcggc aggaccggct taacacctga acgagtggct attaatcaag
     9481 atgatgctcg catacctgat aacgaaggca atcaaccaat tgatacaccg attcgtattg
     9541 atggagcatc ggcctatttt agtagtttac ctatcaaagc gatggtacaa gctatcaaaa
     9601 aacagggact tccggcagtt gtatccaata gtgcaggaac ctttgtttgc aatcatttga
     9661 tgtaccaagc tctttattta gtggataaaa aattccctaa tatgagagca ggtttcatgc
     9721 atattccata tatgatggaa caagtagtaa ataagccgaa tactgcagga atgagtctat
     9781 gtgatattgt aagaggcata gaggtagcta ttgaagctat tgtagactac aaagataagg
     9841 atttgcagtt agtaggcggt gagactcact gataacctaa aaaggatagt caattatgct
     9901 tgtttactaa ctattaacta tgctaaatcg attgaggttg tttacataaa actctatatc
     9961 agagaagcct gatatagagt tttttcttgc tagttttagg attttcttgt aaaatagaaa
    10021 aagtgaagag aggtatgaaa tgagcaagaa agataaaaaa atcgaaattc aagtagcgga
    10081 tgccaaagtt aatgttggta aagacagttt tgaaggttat acattgacta tcggtaaaaa
    10141 agttatcgga gaaattgccg aattagacgg acaatttgcc attataaaga atgggaatgt
    10201 cgatagtttt tataaaaaat tggaaaaagc tgtggaaatt ttgattgaaa attataattt
    10261 agcaaaataa gtcttgtttt tttgaaattt tcatgatata atagtccatg ttgattgtag
    10321 gagagatagc gaagaggcta aacgcggcgg actgtaaatc cgctccttcg ggttcggggg
    10381 ttcgaatccc tctctctcca tttcattaat ggggtatagc caagcggtaa ggcaagggac
    10441 tttgactccc tcatgcgttg gttcgaatcc agctacccca gttcttaggt aataatcaag
    10501 ataaaaagca aaatatctta gggtatttta tttttataat tgaaagacgt gaatgatatg
    10561 aacatgtcct tgcgggtgct taggaaaaaa attataagta tgtcaagttt aagaaaaact
    10621 tgattgttgg aggatttttt agatgaatga atttgaagat ttgctaaata gcgttagtca
    10681 agttgagact ggtgatgttg ttagtgctga agtattgaca gttgatgcga ctcaagctaa
    10741 cgttgcaatc tctggaactg gtgttgaagg tgtcttgact cttcgcgaat tgacaaacga
    10801 tcgtgatgca gatatcaatg actttgttaa agtaggagaa gtattggatg ttcttgtact
    10861 tcgtcaagta gttggtaaag atactgatac agttacatac cttgtatcta aaaaacgcct
    10921 tgaagctcgc aaagcatggg acaaacttgt tggtcgcgaa gaagaagttg ttactgttaa
    10981 aggaacgcgt gccgttaaag gtggactttc agtagaattt gaaggtgttc gtggatttat
    11041 cccagcttca atgttggata ctcgtttcgt acgtaacgct gagcgttttg taggtcaaga
    11101 atttgatact aaaatcaaag aagttaacgc taaagaaaac cgcttcatcc tttcacgtcg
    11161 tgaagttgtt gaagcagcta ctgcagcagc tcgcgctgaa gtattcggta aattggctgt
    11221 tggtgatgtt gtaactggta aagttgctcg tatcacaagc ttcggcgctt tcgtcgatct
    11281 tggtggtgtt gacggattgg ttcacttgac tgaattgtca catgaacgta atgtatcacc
    11341 aaaatcagtt gtaactgttg gtgaagaaat tgaagtgaaa atccttgatc ttaacgaaga
    11401 agaaggacgt gtatcacttt cacttaaagc aacagtacca ggaccatggg atggcgttga
    11461 gcaaaaattg gctaaaggtg atgtagtaga aggaacagtt aaacgtttga ctgacttcgg
    11521 tgcatttgtt gaagtattgc caggtatcga tggacttgtt cacgtatcac aaatttcaca
    11581 caaacggatt gaaaacccaa aagaagctct taaagttggt caagaagttc aagttaaagt
    11641 tcttgaagtt aacgcagatg cagaacgcgt gtcactttct attaaagctc ttgaagaacg
    11701 tccagcccaa gaagaaggac aaaaagaaga aaaacgtgtt gctcgtccac gtcgtccaag
    11761 acgtcaagaa aagcgtgatt tcgaacttcc agaaacacaa acaggatttt caatggctga
    11821 tttgtttggt gatatcgaac tttaatcaaa ttgaaaattc acaaaatcct ttgtttacta
    11881 aacaaaggat ttttctggct ctttgtcaac tgtagtgggt tgaaaaaaag ctaagctcga
    11941 gaaaggacaa atttcgtcct ttcttttttg atattcagag cgatgaaaat ccgttttttg
    12001 aagttttcaa agttccgaaa accaaaggca ttgcgcttga taagtttgat gagattattg
    12061 gtcgcttcca gtttggcatt agaatagtgt agttgaaggg cgttgacaat cttttcttta
    12121 tctttgagga aggttttaaa gacagtctga aaaataggat gaacctgctt tagattgtcc
    12181 tcaatgagtc cgaaaaattt ctccggtttc ttattctgaa agtgaaacag caagagttga
    12241 tagagctgat agtggtgttt caagtcttct gaatagctca aaagcttgtc taaaatctgg
    12301 atattagggt ctttaatgtc tagtaatttt gtgataaaat gtaattgttc catatgaatc
    12361 tttctaatga gttgtttggt cgcttttcat tatagatctt atgggacttt ttttctacaa
    12421 taaaataggc tccataatat ctataggggg gttacccact acaaatatta tagagcccaa
    12481 aatcctttgt ttactaaaca agggattttt cttttgtctc tgctcctttt ttgatataat
    12541 agttctatgt taaaatcaga aaaacaatca cgttatcaaa tgttaaatga agaattgtcc
    12601 ttcctattgg aaggcgaaac caatgttttg gctaatcttt ccaacgccag tgctctcata
    12661 aaatcacgtt ttcctaatac cgtatttgca ggcttttatt tgttcgatgg aaaggaattg
    12721 gttttaggcc ccttccaagg aggtgtttcc tgcatccgta ttgcactagg caagggtgtt
    12781 tgtggtgagg cagctcactt tcaggaaact gttattgttg gagatgtgac gacctatctc
    12841 aactatattt cttgtgatag tctagctaaa agtgaaattg tggtgccgat gatgaagaat
    12901 ggtcagttac ttggagttct ggatctggat tcttcagaga ttgaggatta cgatgctatg
    12961 gatcgagatt atttggaaca atttgtcgct attttgcttg aaaagacaac atgggacttt
    13021 acgatgtttg aggaaaaatc ttaatgtatc aagcacttta tcgaaaatat agaagtcaaa
    13081 acttctccca gttagttggt caagaagttg tggctaagac tcttaaacaa gcggtggagc
    13141 aagagaaaat aagtcacgct tatctttttt ctggtcctcg tggaacggga aaaaccagtg
    13201 ttgctaaaat ctttgccaag gctatgaact gtcccaatca agtgggtggc gaaccttgca
    13261 ataactgcta tatttgtcaa gcagtgacgg acggtagttt agaagatgtc attgaaatgg
    13321 atgcagcttc taataatggg gtagatgaaa ttcgcgaaat tcgtgataaa tctacctatg
    13381 cgcctagcct tgctcgttat aaggtttata tcatagatga ggttcacatg ctgtctacag
    13441 gggcttttaa tgccctccta aagacgctgg aagaaccaac acagaatgta gtctttattt
    13501 tggccactac tgaattgcac aagattcctg ctactattct atcccgtgtg caacgttttg
    13561 agtttaaatc aattaagaca caggatatta aggaacatat tcactatatc ttagaaaaag
    13621 aaaatatcag ttctgaacca gaggctgtgg aaatcattgc cagacgggcg gaaggtggaa
    13681 tgcgggacgc cttgtctatt ttggatcaag ccctgagttt gacacaggga aatgagctga
    13741 cgactgctat ctctgaagaa attactggca ccattagcct atcagccttg gatgattatg
    13801 tggcggcctt gtctcaacag gatgttccca aagctttgtc ttgcttgaat cttctttttg
    13861 acaatggtaa gagcatgact cgttttgtga ccgatctttt gcactattta agagacttgt
    13921 taattgttca aacaggggga gaaaatactc atcatagttc agtctttgta gaaaatttgg
    13981 cacttcctca aaaaaatctg tttgaaatga ttcgcttagc aacagtgagt ttagcagata
    14041 ttaagtctag tttgcagccc aagatttatg ctgaaatgat gaccgtccgt ttggcggaaa
    14101 tcaagcccga accagctcta tcaggagcgg ttgaaaatga aattgctacg ctgagacagg
    14161 aagttgcccg tctcaaacaa gagctttcta atgtaggtgc ggttcctaaa caagttgcac
    14221 cagctcctag tcgaccagct acgggcaaaa cagtctatcg tgtcgatcgc aataaagtgc
    14281 aatctatctt acaagaggcc gtcgaaaatc ctgatttagc acgtcaaaat ctaattcgtt
    14341 tgcagaatgc ctggggagag gtaattgaaa gtctaggtgg gccggacaag gctctgctag
    14401 ttggttctca accggttgct gccaatgaac accatgctat tcttgctttt gagtctaact
    14461 tcaatgctgg tcaaactatg aaacgagaca atctcaatac catgtttggt aatatcctca
    14521 gtcaggcggc aggtttttca cctgagattt tagctatttc catggaggaa tggaaagaag
    14581 ttcgcgcagc cttttcagcc aaagccaaat cttctcaaac tgaaaaagaa gtagaagaaa
    14641 gcctgattcc agaaggattt gaatttttgg ctgataaagt gaaggtagag gaagactaaa
    14701 gaaagatttc atgatacaat aagtttatga ataaacaaca atttattatt atggcgctgt
    14761 ttacagctgc tgagacctat tttttcaatg aagcctggat gactggccgc tatattatgg
    14821 cagccttttg ggcaatttta ctctttagaa atttccgagt cagttatgtg atgggcaaaa
    14881 tcgttgatgt catcgatcag cattttaata ggaaagacta gccctcagct tccagacaaa
    14941 atcaaagcct tttaggcttt tttttgttat actagaaaag tatatttata gaatttttgc
    15001 tctatttctg gggaaatcag acgtttttct agtaagtact gtaaaagttt tgaaaaagaa
    15061 aggaactatc atgtcagtat tagagattaa agatcttcac gttgagattg aaggaaaaga
    15121 aattttaaaa ggggttaacc tgaccctgaa aacaggagaa attgccgcta tcatgggacc
    15181 aaatggtaca ggtaaatcga ctctttctgc cgctatcatg ggaaatccaa actatgaagt
    15241 aactaaaggt gaagttttgt ttgatggcgt aaacatcctt gagttggaag tggatgagcg
    15301 tgcgcgtatg ggacttttcc ttgctatgca atacccatca gaaatccctg gaattaccaa
    15361 tgctgagttt cttcgtgccg ctatgaatgc gggtaaagaa gatgatgaga agatttcagt
    15421 tcgtgagttt attactaagc tagatgaaaa aatggaattg ctcaacatga aagaagaaat
    15481 ggcagagcgt tacctcaacg aaggcttctc tggtggtgag aaaaaacgca atgaaattct
    15541 tcaacttttg atgttggagc caacatttgc tcttttggac gagattgact caggtcttga
    15601 tattgacgct cttaaagttg tgtctaaagg tgtcaatgcc atgcgtggtg aaggttttgg
    15661 tgctatgatc atcactcact accaacgtct tttgaactat atcacacctg atgtggtaca
    15721 cgtgatgatg gaaggtcgtg ttgtcctttc tggtggtcca gaattggctg cgcgtttgga
    15781 acgtgaagga tacgcaaaat tagctgaaga acttggctac gactacaagg aagaattgta
    15841 atttcctcgt atcttttagg agaagtaaat gactagagaa aatattaaac ttttttcaga
    15901 aatgcacgct gaaccaagct ggttggctga tctccgtcaa aaagcttttg acaagattga
    15961 gactttggaa ttaccagtta ttgagcgtgt caaattccac cgttggaatc tgggtgatgg
    16021 aacgattaca gaaaatgagc catcagcaaa tgttccagat ttcacagctt tagatcatca
    16081 cttgaagttg gtgcaagtag gaactcaaac tgttttcgaa caaactccag ttgagttagc
    16141 tgaacagggt gttgtcttca cagactttca ctcagcttta gaagaaattc cagagctgat
    16201 cgaagaattc ttcatgtcat ctgttaagta tgatgatgac aagttggcgg cttaccacac
    16261 agcttacttt aacagtggtg ctgtactcta tattccagat aacgtagaaa tcacagagcc
    16321 aattgaagga attttctacc aagatagcga tagcaatgtg ccgtttaaca agcatattat
    16381 gattatcgct ggtaaaaatt ctaagattag ttatctggag cgtttagagt cacgcggtga
    16441 aggaagtgac aaagtaactg ccaatatcac agtggaagtg attgcacgtt ctggtgcgca
    16501 agtcaagttt gctgctatcg accgtctagg tgaaaacgtc actgcctaca ttagccgtcg
    16561 tggtaaatta ggcaacgatg caagtattga ctgggctatc ggtgtcatga acgaaggaaa
    16621 tgtcgttgct gattttgata gtgacttgat tggtaatggt agccatgctg acctcaaggt
    16681 tgtagctctt tcaagtggtc gtcaggtaca agggattgat actcgtgtaa ctaactatgg
    16741 ctgcaactct atcggaaata tcctacaaca tggggttatc cttgaaaaag caactttgac
    16801 tttcaatggt atcggccaca tcatcaaggg tgctaaggga gcagatgcgc aacaagagag
    16861 ccgtgttctc atgctttcag accaagcgcg ttcagatgct aacccaattc ttttgattga
    16921 tgaaaatgat gtcactgcag gacacgcagc gtctatcgga caagttgatc cagaagacat
    16981 gtattacctc atgagtcgtg gattggataa ggcaactgca gagcgtttgg ttgttcgtgg
    17041 tttccttgga tctgttatcg tggagattcc agtcaaggaa gttcgtgatg aaatgattgc
    17101 aactatcgaa gagaaattgt caaaacgcta aggggaagcc tatgttagat gtagaagcga
    17161 ttcgcaagga ttttccaatt ttagatcaga ttgtcaatga tgaacctctg gtctatctgg
    17221 acaatgctgc gacgacacaa aaacccctag tagttctgaa agctattaac agttactatg
    17281 agcaggacaa tgccaatgtt caccgtggtg tccatacctt agcggaacga gcgacagctt
    17341 cttatgaagc tgctcgtgaa accattcgta agtttattaa tgcaggctct acaaaggaag
    17401 ttctctttac cagaggaacg acaaccagcc ttaactgggt ggcacgcttt gctgaggaaa
    17461 ttctcactga gggagaccag gtcttgattt cagtaatgga acaccattct aatatcattc
    17521 catggcagga agcttgtcga aagactggag cagagcttgt ctatgtctat cttaaagacg
    17581 gtgccttgga tatggaggat ttgcgagcta aattgactga taaggttaaa tttgtttccc
    17641 tagctcatgc ctccaatgtt cttggtgtga tcaatccgat caaggaaatc actcaattag
    17701 cccaccaagt tggggcaatc atggtagtgg atggtgctca atctacacct catatgaaga
    17761 ttgatgtcca ggacttggat ctggactttt tcgccttttc gggtcacaag atggctggtc
    17821 cgactggtat cggtgtcctt tacggcaaag aaaagtatct tgagcaaatg tctccagtag
    17881 aatttggcgg cgagatgatt gattttgtct acgagcaatt tgctagttgg aaggaattgc
    17941 cttggaaatt tgaggctgga acgccaaata tggcaggagc tattggactt gcgactgcag
    18001 ttgattattt ggaaaagatt ggtatggatg ccgttgaagc tcatgaacag gaattgattg
    18061 cgtacgtcta tccaaaactg caggcaattg agggattgac catttacggt tctcaggatt
    18121 tggctcaacg ttcgggtgtt attgccttta acctaggtga tctccatcct cacgatcttg
    18181 cgacggctct ggattatgaa ggagtggctg ttcgtgctgg tcaccattgt gcgcaaccct
    18241 tgcttcagta tttggaagtc ccagcaacag ctcgtgcaag tttttatatc tacaatacca
    18301 aggcagattg cgacaaacta gtcgatgccc tacaaaagac aaaggagttt ttcaatggca
    18361 ctttctaaac tagatagcct ttatatggca gtggtagcag accattcgaa aaatccacat
    18421 caccaaggga agttagaaga tgctgagcaa atcagtctca acaatccgac ttgtggggat
    18481 gtcatcaacc tctctgtcaa gtttgatgca gaggaccgtt tggaagatat tgcttttcta
    18541 aattcaggat gcacgatttc aactgcttct gctagtatga tgacagatgc cgttttagga
    18601 aaaaccaaac aagaaatttt agaactggcg actatttttt ctgaaatggt tcaagggcaa
    18661 aaagatgagc gtcaaggcca acttggagac gcggcattct tgtcaggtgt tgccaaattc
    18721 cctcaaagaa tcaagtgtgc aaccctagct tggaatgccc ttaagaaaac aattgaaaat
    18781 caagaaaaac agtaagacaa gtttcttttg tcttatgaat tattagaaat gaagaaagaa
    18841 aggatactat ggctgaagaa agagtagaac caaaaccaat tgaccttggt gaatataaat
    18901 ttggtttcca tgacgatgta gagcctgtct tatcgacagg aaaaggactc aacgaaggtg
    18961 ttattcgtga attatctgct gctaagggtg agcctgagtg gatgttggag ttccgtttga
    19021 agtcttatga aaccttcaaa aaaatgccca tgcaaacttg gggagcagac ttgtcagaga
    19081 ttgactttga tgacttaatc tactaccaaa aaccatctga caaaccagcc cgttcttggg
    19141 atgatgtacc tgaaaagatt aaagaaacct ttgaacgtat cgggattcca gaagctgaac
    19201 gtgcttattt agcaggggct tctgcccagt acgagtcaga agtggtttac cacaacatga
    19261 aggaagagtt ccaaaaatta ggtattatct ttacagatac agattccgca ctcaaggaat
    19321 acccagactt atttaaacaa tactttgcga agttggtacc gccgacagat aacaagttgg
    19381 cagccctcaa ctcagcagta tggtcgggtg gaacttttat ctacgtgcca aaaggtgtca
    19441 aggtagatat tccacttcaa acttatttcc gtatcaataa cgaaaatata ggtcagttcg
    19501 aacgtacctt gattatcgtt gatgagggag caagcgtcca ctacgtagaa ggatgtacag
    19561 caccaacata ttcaagcaat agcttacacg ctgccattgt agaaattttt gctttggacg
    19621 gagcttatat gcgttataca actatccaaa actggtctga taacgtctat aacttggtaa
    19681 caaagcgtgc taaggctcaa aaggatgcca ctgttgagtg gattgatgga aacttgggtg
    19741 ccaaaacgac tatgaaatat ccatctgttt accttgatgg agaaggagcg cgtggtacca
    19801 tgctctctat cgcctttgct aatgcagggc aacaccaaga cacgggtgct aagatgattc
    19861 acaatgctcc acataccagc tcgtctattg tgtctaaatc catcgctaaa ggtggaggaa
    19921 aggttgacta ccgtggacaa gtcaccttta acaagaactc taagaaatct gtttcccaca
    19981 ttgaatgtga taccattatc atggatgact tgtcagcatc agatactatt ccatttaatg
    20041 aaattcacaa ctcgcaagtg gctttggaac acgaagccaa agtatctaag atttcagaag
    20101 agcaattgta ttatctcatg agccgtggat tgtcagaatc tgaggcaact gaaatgattg
    20161 tcatgggatt tgtagaaccc tttacaaaag aacttccaat ggaatacgca gttgagctga
    20221 accgcttgat tagctatgaa atggagggat cagttggata aaatttgatt ttatactctt
    20281 cgaaaatctc ttcaaaccac gtcagcatcg ccttaccgta tgtatggtta ctgacttcgt
    20341 cagtttcatc tacaacctca aaacagtgtt ttgagcaagc tgcggctagc ttcctagttt
    20401 gttctttgat tttgagtatt agatttactc aaaatcaagg attttgaaga tgaacttgta
    20461 tcaaaaaatc gcggtttaaa atcgcgattt tttataattt ctcgttaaca aagcggacaa
    20521 actgattcca ccaaactttt aagaagaagg ctttttcaat tttcttgtct gctaccattt
    20581 cgaaactagg gcgctctgtg gtgatgtaac cttgaccaat caagtccttg tcttcataag
    20641 tcaaatggcc aaccactgtt ccagcttcaa gtggtgctgg gattgctttg gaatcaggtg
    20701 tgaattgaac agattgggaa gattgattcc caacacgttc gattagatag atatcctctg
    20761 gagccactgc agttactgta tcttcttttc catcttgtac aggggttttg ctatcttgat
    20821 aggcatcgcc ttgttgaacg attttgcgaa gtgtaaatgt agaagaaata taatccatta
    20881 gggaagatgt agctgtaaat cgagcgtaag gattattgtc ttgatgatct gcatttaaaa
    20941 caactgtgat gactctcatg cctttttcga cagtagtacc aacaaaagac tctccagcct
    21001 tatctgttgt tcctgttttt agcccatcaa aaccaccacg gtaagcaggc ataccttcta
    21061 acatgtagtt ggttgaagtg attgtcatcc cagcaaaagt agaagaaggt tttttggtga
    21121 tttctaagac ttgtgggtat tttttgatga ggttgcgagc aacgatagcg acatcataag
    21181 cactaagctt attttcctca tcttttttag aacctgggta aatgttatcc cctagagttt
    21241 cattgttaag acctgtcgta ttgacaacag tggcatcctg aattccccat tccaagagtt
    21301 ttgcccgcat catatcgacg aaatcttttt ctgagccagc aattttctca gctagggcaa
    21361 tagcggcgct gttggcacta gataccagag ttgcttcaag caactcttcg acagtataat
    21421 tacgggcctc cataggaata ttactggctt cagaatttgt cgtcaattga taaggataat
    21481 cagaaatatc tacaggagtg gagagggtaa tacttccgtt ttccaaagct tcatagacca
    21541 gataaacagt aatcaatttt gttatggaag caatttcgac aggttgcgtt gcatccttct
    21601 catagagaat tttaccagta tttgcctcaa cagcaatcgc atgtttagcg gcaatggtaa
    21661 aatcttgagc aacagcagta gaagcacccc ctaaaagaga gacagttaac aaagttaaaa
    21721 atattttttt catagtagtc ttattctatc ataaagaaaa aaaatattct tgctttaata
    21781 attcatctgt taagcttttt gaaaatatgg taaaataaag tgagggaggt aactcatgtt
    21841 tcgtagaaat aaattatttt tttggaccac agaaatttta ctcttaacca tcatctttta
    21901 cctatggaga cagatgggat ctttgattaa cccttttgtt agcgtgctta atacaattat
    21961 gattccattt ttattagggg gctttcttta ttatttgaca aaccctattg ttactttctt
    22021 aaataaagtc tgtaaactca atcgtttgct tggtatttta attaccttgt gtactttggt
    22081 ctggggaatg gtcataggtg ttgtctatct cttacctatt ttgattaatc agttatctag
    22141 tttgattata tctagtcaaa ctatttatag tcgagtacaa gacttaatca tagacttatc
    22201 taattatcct gcgctccaga atttggatgt agaagctaca attcagcagt taaacttatc
    22261 ctatgttgat attcttcaaa atatcctaaa tagcgtatca aatagtgtgg ggagcgtctt
    22321 gtcagctctt atcagtactg ttttgatttt gattatgact ccagtttttt tggtttattt
    22381 cttattagat ggacataaat tcttgcccat gcttgaaaga acgattctaa agagggatcg
    22441 cttgcatatt gcaggcttat taaagaattt aaatgcgacg attgctcgct atattagtgg
    22501 agtttcgatt gacgcaatca ttataggttg tttggcttat attggctata gtattattgg
    22561 tttaaaatat gctttagttt ttgccatttt ttctggtgta gccaatttaa ttccttatgt
    22621 ggggccaagt attggtttga ttcctatgat catcgcaaat atattcactg atccccatag
    22681 actgctgatt gcagtgattt atatgcttgt tgttcagcag gtagatggca atatcttata
    22741 tcctcgaatc gtaggaagtg ttatgaaggt tcatccaatc acgattttag ttttactttt
    22801 gttgtcaagc aatatctatg gtgtagttgg aatgattgtc gcagtgccaa cctattctat
    22861 cttgaaagaa atttctaagt tcttatcccg tttgtatgaa aatcataaaa taatgaaaga
    22921 acgagaaaga gaattagcta agtaaaagtc aggagaaccc tgatttttct ttactggaag
    22981 tggcctttag attagaagac tgaaaataag ttaaagtctt aaactaattt tcacagctaa
    23041 gaatagtaga agttaatctg ataaaaatcg aaaaaaccag tggaattctg tgtcagggta
    23101 agttccactg gttttcatag tctattaaag ttcgaatgaa acctatttat agtagattga
    23161 aactagaata gtacacctct aattctaaaa cattgttaga aatcgatttg actgtcctga
    23221 tctattcgtc ctattcttat ttcattttac tatattttgg tgcaataagt gaaaagtaga
    23281 ccgaataata taaggattga ttttatagtt tttaaactca aatgaattga aataaagaga
    23341 gtacgaaaat tctcatctga aagtatttta gaataattct cttcgtgaat ttcttcaaaa
    23401 cagatagctt catcttaggt atgtgatttc tttttgcatt tttgagttag ataaggtata
    23461 atggttttat tgtcttttgg ggtcgttacg gattcgacag gcattatgag gcatattttg
    23521 cgactcgtgt ggcgacgtaa acgctcagtt aaatataact gcaaaaaata acacttctta
    23581 cgctctagct gcctaaaaac cagcaggcgt gacccgattt ggattgctcg tgttcaatga
    23641 caggtcttat tattagcgag atacgattaa gccttgtcta gcggtttgat aagagattga
    23701 tagactcgca gtttctagac ttgagttatg tgtcgagggg ctgttaaaat aatacataac
    23761 ctatggttgt agacaaatat gttggcaggt gtttggacgt gggttcgact cccaccggct
    23821 ccattattcc tttgcattcc ttggtaaaac gttgttaaat caacgttttt tatttttatc
    23881 tttggtattc ctttgcattc ttttgctaaa aagggagtca caaacagacc ctattttaaa
    23941 aaaaggatag aaaaaaggat acaacatttg tcgcatccta aaaataatct tttttcgacg
    24001 gaagacatgg gattcgaacc cacgcacgct attacacgcc taccgcgttt ccaacacggc
    24061 ctcttaagcc tcttgagtaa tcttccaata cttactcaaa tagtctacca taaaggctct
    24121 tatcttgcaa taaaaattct agaaataaga aaaaatgata gattttgaaa gaaaatgata
    24181 aaaaatgctt gacttcgaaa gaaagtatga tagaatgaat agtgtaaacg ataacaggag
    24241 gtgattcagt gttaaaaaca gaacgtaaac aactaatttt agaggagtta aatcagcatc
    24301 atgtagtttc tctagaaaaa ttagttagtt tgctagaaac gtcagaatca acggttcgaa
    24361 gagacttgga tgagttggaa gcggaaaaca agcttcgtcg tgtgcatggt ggagcagaac
    24421 tcccccactc cttacaggaa gaagaaacca ttcaagaaaa atctgtcaaa aaccttcaag
    24481 aaaagaagtt gctggctcag aaagcagcct ctctcattaa agaaaaagat gtcatcttta
    24541 tcgatgctgg aacaacaact gcttttttga ttcatgaatt ggtcaataag aatgttacag
    24601 ttgtgaccaa ctccattcac catgccgctc agttggttga aaagcagatt ccaactgtca
    24661 tggttggagg aaacgtcaag acggcgacag atgctagtat cgggggcgtt gctcttaacc
    24721 agattaacca attgcacttt gaccgtgcct ttatcggaat gaatggtgtt gacgatggct
    24781 attatacgac tcctgatatg gaggagggag ctgtgaaaag agctattttg gagaatgcca
    24841 agcagaccta cgtcttggtg gattcgtcaa aaattggaca aacttgcttt gccaaggtag
    24901 caccactcaa acgcgctatc gttatcacta gtcaagggca tgagctcttg caggttatta
    24961 aggagaaaac ggaggtaata gaagtatgat ttatacagtc acactcaatc catccattga
    25021 ctatatcgtt cgtttggacc aagtcaaagt tggtagtgtc aatcgtatgg acagtgatga
    25081 taagtttgct ggtgggaaag gaatcaatgt cagccgtgtc ttgaaacgtt tgaatatacc
    25141 aaatacagcg acgggattta tcggtggctt tactggtaaa tttatcacag atactctagc
    25201 agaggaagaa atcgagacac gttttgtcca agtggcagaa gatactcgta tcaatgttaa
    25261 aatcaaagca gaccaagaaa cagaaatcaa cggaacgggt ccaactgttg aaccggttca
    25321 gctagaagaa ttgaaagcta ttttatctag tctgacagta gaagatacag ttgtctttgc
    25381 aggttcaagt gctaaaaatc taggcaatgt tatctataag gatttgattt ccttgacgcg
    25441 ccagactggt gcgcaagtgg tctgtgactt tgaaggacag accttaattg atagtttgga
    25501 ctaccagcct cttcttgtaa aaccaaacaa tcatgaactt ggagcgattt ttggggttaa
    25561 actcgaaagt ttagatgaaa ttgagaaata cgctcgtgag ttactggcta agggtgctca
    25621 aaatgttatt atctctatgg ctggtgatgg cgcccttctt gtcacatctg agggagctta
    25681 cttcgctaaa ccaatcaaag gaacagtcaa aaattcagtt ggagctggtg attctatggt
    25741 tgctggattc acaggtgaat ttgtcaaatc aaaagacgca gtagaagcct tcaaatgggg
    25801 agtggcttgc ggaacggcaa ctaccttctc agatgacttg gcaacggcgg aatttattaa
    25861 agaaacatat ggaaaagttg aggtagaaaa aagatgaaaa ttcaagacct attgagaaaa
    25921 gatgtcatgt tgctagattt gcaggcaact gaaaaaacag ctgtcatcga cgagatgatt
    25981 aaaaatttga cagagcacgg ttatgtaaca gattttgaaa catttaaaga aggaattttg
    26041 gcgcgtgaag ctttgacttc tactggtttg ggtgatggaa tcgcaatgcc tcacagcaaa
    26101 aacgctgctg tcaaagaagc gacagttcta tttgctaagt caaacaaggg tgttgactac
    26161 gagagcttgg atggacaagc aactgacctc ttcttcatga ttgcagctcc agaaggtgcc
    26221 aatgatactc acttggcagc cttggcagaa ttgtctcaat acttgatgaa agacggtttt
    26281 gcagacaaac ttcgtcaagc aacatctgca ggccaagtta tcgaactttt tgaccaagct
    26341 tcagaaaaaa ctgaggaact tgttcaagca cctgctaatg actctggtga ctttatcgta
    26401 gctgttacag cttgtacaac aggtattgcc cacacttaca tggcccaaga agcccttcaa
    26461 aaagtagctg ctgaaatggg ggttggtatc aaggtcgaaa ccaacggtgc tagcggtgtt
    26521 ggaaatcaac taactgcaga agatatccgt aaggctaaag ctattatcat tgcagcagac
    26581 aaggccgttg aaatggatcg atttgatgga aaaccattga tcaatcgtcc agttgctgac
    26641 ggtatccgta agacagaaga gctaattaac ttggctcttt caggagatac tgaagtctac
    26701 cgtgccgcta atggtgccaa agctgcaaca gcctctaacg aaaaacaaag ccttggtggt
    26761 gccttgtaca aacacttgat gagtggtgta tctcaaatgt taccattcgt tatcggtggt
    26821 ggtatcatga ttgcccttgc cttcttgatt gacggtgctt tgggtgttcc aaatgaaaac
    26881 cttggcaatc ttggttctta ccatgagtta gcttctatgt ttatgaaaat tggtggagct
    26941 gcctttggtt tgatgcttcc agtctttgcg ggttatgttg cctactctat tgctgaaaaa
    27001 ccgggtttgg tagcaggttt cgtggctggt gctattgcca aagaaggttt tgcctttggt
    27061 aaaattcctt atgccgcagg tggtgaagca acttcaactc ttgcaggtgt ctcatctggt
    27121 ttcctaggtg cccttgttgg tggatttatc gcaggtgcct tggttcttgc catcaagaaa
    27181 tacgttaaag ttcctcgttc actcgaaggt gctaaatcaa tccttctatt gccacttctt
    27241 ggaacaatct tgacaggatt tgttatgcta gctgtgaata tcccaatggc tgcaatcaac
    27301 actgctatga atgacttcct aggcggtctt ggaggaggtt cagctgtcct tcttggtatc
    27361 gtccttggtg gaatgatggc tgttgacatg ggtggaccag ttaataaagc agcttatgtc
    27421 tttggtacag gtacgcttgc agcaactgtt tcttcaggtg gttctgtagc catggcagca
    27481 gttatggctg gaggaatggt gccaccactt gcaatctttg tcgcaactct tcttttcaaa
    27541 gataaattta ctaaggaaga acgtaactct ggtttgacaa acatcatcat gggcttgtca
    27601 tttatcactg agggagcgat tccatttggt gccgctgacc cagctcgtgc gattccaagc
    27661 ttcatccttg gttcagcagt agcaggtgga ctcgttggtc ttactggtat caaactcatg
    27721 gcgccacacg gaggaatctt cgttatcgcc cttacttcaa atgctctcct ttacctcgtt
    27781 tctgtcttgg taggagcaat cgtaagtggt gtggtttatg gttacctacg caaaccacaa
    27841 gcataaaaaa tagaaaaatg aaaagattgg accgtttggt gcagtctttt tctcttcccg
    27901 aaatgcctgt gaaatatggt ataatagaag aatggcaaac aagaatacaa gtacaacaag
    27961 acggagaccg tctaaagcag aactggaaag aaaagaagcg attcaacgaa tgttgatttc
    28021 gttaggaatt gcgattttat tgattttcgc agccttcaaa ttaggggctg caggtataac
    28081 cctttataat ttaattcgct tgctagtggg tagcctagct tatctggcga tattcggcct
    28141 attaatctat ctcttctttt tcaagtggat acgaaaacag gaaggactct tatctggctt
    28201 tttcaccata tttgctggct tactcttgat ttttgaggcc tacttggttt ggaaatatgg
    28261 tttggacaag tccgttctaa aagggaccat ggctcaggtt gtgacagatc tgactggttt
    28321 tcgaacgact agctttgctg gagggggctt gatcggggtc gctctttata ttccaacagc
    28381 ctttctcttt tcaaatatcg gaacttactt tattggttct atcttgattt tagtgggttc
    28441 tctcctagtc agcccttggt ctgtttacga tattgctgaa tttttcagta gaggctttgc
    28501 caaatggtgg gaagggcacg agcgtcgaaa agaggaacgc tttgtcaaac aagaagaaaa
    28561 agctcgccaa aaggctgaga aagaggctag attagaacaa gaagagactg aaaaaacctt
    28621 actcgatttg cctcctgttg atatggaaac gggtgaaatt ctgacagagg aagctgttca
    28681 aaatcttcca cctattccag aagaaaagtg ggtggaacca gaaatcatcc tgcctcaagc
    28741 tgaacttaaa ttccctgaac aggaagatga ctcagatgac gaagatgttc aggtcgattt
    28801 ttcagccaaa gaagcccttg aatacaaact tccaagctta caactctttg caccagataa
    28861 accaaaagat caatctaaag agaagaaaat tgtcagagaa aatatcaaaa tcttagaagc
    28921 aacctttgct agctttggta ttaaggtaac agttgaacgg gccgaaattg ggccatcagt
    28981 gaccaagtat gaagtcaagc cggctgttgg tgtaagggtc aaccgcattt ccaatctatc
    29041 agatgacctc gctctagcct tggctgccaa agatgtccgg attgaagcac caatccctgg
    29101 gaaatcccta atcggaattg aagtgcccaa ctccgatatt gccactgtat ctttccgaga
    29161 actatgggaa caatcgcaaa cgaaagcaga aaatttcttg gaaattcctt tagggaaggc
    29221 tgttaatgga accgcaagag cttttgacct ttctaaaatg ccccacttgc tagttgcagg
    29281 ttcaacgggt tcagggaagt cagtagcagt taacggcatt attgctagca ttctcatgaa
    29341 ggcgagacca gatcaagtta aatttatgat ggtcgatccc aagatggttg agttatctgt
    29401 ttacaatgat attccccacc tcttgattcc agtcgtgacc aatccacgta aagccagcaa
    29461 ggctctgcaa aaggttgtgg atgaaatgga aaaccgttat gaactctttg ccaaggtggg
    29521 agttcggaat attgcaggtt ttaatgccaa ggtagaagag ttcaattccc agtctgagta
    29581 caagcaaatt ccgctaccat tcattgtcgt gattgtggat gagttggctg acctcatgat
    29641 ggtggccagc aaggaagtgg aagatgctat catccgtctt gggcagaagg cgcgtgctgc
    29701 aggtatccac atgattcttg caactcagcg tccatctgtt gatgtcatct ctggtttgat
    29761 taaggccaat gttccatctc gtgtagcatt tgcggtttca tcaggaacag actcccgtac
    29821 gattttggat gaaaatggag cagaaaaact tcttggtcga ggagacatgc tctttaaacc
    29881 gattgatgaa aatcatccag ttcgtctcca aggctccttt atctcggatg acgatgttga
    29941 gcgcattgtg aacttcatca aggctcaggc agatgcagac tacgatgaga gttttgatcc
    30001 aggtgaggtt tctgaaaatg aaggagaatt ttcggatgga gatgctggtg gtgatccgct
    30061 ttttgaagaa gctaagtctt tggttatcga aacacagaaa gccagtgcgt ctatgattca
    30121 gcgtcgttta tcagttggat ttaaccgtgc gacccgtctc atggaagaac tggagatagc
    30181 aggtgtcatc ggtccagctg aaggtaccaa acctcgaaaa gtgttacaac aataaaaaaa
    30241 tagcttcttt ccgagtttgg agggaagcta ttttagtggc tattgattgc ttttattttc
    30301 tgaagttggc gcattggact gtttttcgtt ttcagtagca ggtttacttg aagcaggagt
    30361 agaagagtcc tgagttgctg ttttctgatc ttcttttttc tcttccttga cgctagattt
    30421 tggtgtttcc tcttgctgtg ttttttcttg actagtgtta gtctctttag ttggactggt
    30481 gttttcctta ggggattcct tttggatttc tttgacaatg gttgtcgtct ggcttgtcgt
    30541 aggttctttt ttaatatttt tgttattatc caaggcgttc atgatcgtga tacccgcggt
    30601 aatcaagcca aggatactag cgattgtagc aacggttttt tgaaagactg taaagccttt
    30661 tttgatgtgt tctgtttttg gttttgaagt tctacgatag ttagacatac attctctcct
    30721 ttgattatga tttattatac tctgtttctt taaaaaaatc ttaaaaaaag agaaattgcc
    30781 ctttcttgtc gcaggctccg tttcatgata caatagaagg agtgatttta gaaagcgtga
    30841 gaaacatgat ttactttgat aattcggcga cgaccaggcc ctatccagaa gcccttgaaa
    30901 cctatatgca ggtggcttca aaaattttag gaaatccatc tagtctccat cgtttgggag
    30961 accaggcaac acgaatttta gatgcttccc gtcaacagat tgcagattta atcggtaaga
    31021 aaagtgatga aatcttcttt acatctggtg ggacagaagg ggataactgg atcatcaagg
    31081 gagtagcatt tgaaaaagcc cagtttggca agcacatcat cgtatcagcc attgaacatc
    31141 cagcagttaa ggaatcagcc ctctggttga aagctcaagg ttttgaagtg gattttgctc
    31201 cagttgataa caaaggattt gtggatgttg aggcgctaga agatttgata agacctgata
    31261 cgaccctcgt ttccatcatg gcagttaaca atgaaattgg ctctgttcag cccattgagg
    31321 ctatttcaaa actattggca gacaagccaa ctatttcctt ccacgttgat gcggttcagg
    31381 cgcttgccaa gattccgact gaaaagtatc tgacagaacg agtggatttc gcgactttct
    31441 ctggtcacaa gttccacgga atccgtggtg ttggttttat ctatatcaag tctggcaaga
    31501 agattacgcc tcttttaaca ggtggtggtc aggaacgtga ttaccgttcg acaactgaaa
    31561 atgtggcagg aattgcagcg accgctaagg ctctccgttt atctatggaa aagctagata
    31621 tctttaggag caagactggg cagatgaagg cagtgattcg tcaagcactt ctggactatc
    31681 cggatatatt tgtcttttca gatgaggaag acttcgcccc tcatattctg acttttggaa
    31741 tcaagggtgt tcgtggtgag gtcattgttc acgcctttga agactatgat attttcatct
    31801 caacgacctc ggcttgttcg tccaaggctg ggaaaccagc cggaaccctg attgctatgg
    31861 gagtggacaa ggataaggct cagtcagctg tgcgtcttag tctagacctt gaaaatgata
    31921 tgagtcaggt cgagcagttc ttgaccaagc taaaattaat ttacaatcaa actagaaaag
    31981 taagatagga gcattcatgc agtattcaga aattatgatt cgctacggtg agctgtcaac
    32041 caagggcaaa aatcgtatgc gtttcatcaa taaacttcgc aataatattt cagacgtttt
    32101 gtctatctat ccccaagtta aggtaacagc agatcgcgac cgtgcccacg cttacctcaa
    32161 tggagcagat tacacagcag tagcagaatc actcaaacaa gtatttggaa ttcaaaactt
    32221 ttcccctgtt tataaggttg aaaaatctgt agaagttctg aagtctgctg tccaagagat
    32281 tatgcaggac atctacaagg aaggcatgac ctttaaaatc tctagcaagc gtagcgacca
    32341 cacctttgaa ttggacagtc gtgaactcaa ccaaacgctt ggaagggctg tattcgaagc
    32401 cattccaaac gtacaagctc aaatgaaaag tcctgacatc aatcttcagg tggagatacg
    32461 tgaagaagca gcctatcttt cttatgaaac cgttcgaggg gcaggtggat taccagtggg
    32521 aacttctggt aagggcatgc tcatgttgtc agggggaatc gattcccctg tagctggcta
    32581 tctagcgctt aaacgagggg tagatataga ggcagttcac tttgccagcc caccttacac
    32641 gagtcctggt gctcttaaaa aagcccaaga tttgacccgt aaattaacca aatttggggg
    32701 aaatatccag tttatcgaag ttccttttac agagattcaa gaggaaatca aagccaaagc
    32761 gccagaagcc taccttatga ccttgacgcg tcgttttatg atgcgtatta ctgaccgtat
    32821 tcgtgaggta cgaaatggtt tagttatcat caatggggaa agtctaggtc aagtagccag
    32881 ccaaaccctt gaaagtatga aggctatcaa tgctgttacc aacactccca tcattcgtcc
    32941 tgtggttacc atggacaagt tggaaatcat tgacatcgcc caggaaatcg atacctttga
    33001 catttcaatc caaccgtttg aagactgttg taccattttt gcaccagatc gtccaaaaac
    33061 aaatcctaaa attaagaatg cggagcagta cgaagcgcgt atggatgttg aaggcttggt
    33121 tgagcgagca gtggctggaa tcatgattac tgaaatcaca cctcaagccg aaaaagatga
    33181 agttgatgac ttgattgaca atctgctcta attcagaaaa tccaaaagaa tagcgaaaat
    33241 cagtaaaaaa agttagtttt ttctctaaaa acaggtaaaa aactaacttt ttttattttt
    33301 atgatataat gatataaaat tttgaatata gagagttttc tggcaatgaa tcaatcctac
    33361 ttttatctaa aaatgaaaga acacaaactc aaggttcctt atacaggtaa ggagcgccgt
    33421 gtacgtattc ttcttcctaa agattatgag aaagatacag accgttccta tcctgttgta
    33481 tactttcatg acgggcaaaa tgtttttaat agcaaagagt ctttcattgg acattcatgg
    33541 aagattatcc cagctatcaa acgaaatccg gatatcagtc gcatgattgt cgttgctatt
    33601 gacaatgatg gtatggggcg gatgaatgag tatgcggctt ggaagttcca agaatctcct
    33661 atcccagagc agcagtttgg tggtaagggt gtggagtatg ctgagtttgt catggaggtg
    33721 gtcaagcctt ttatcgatga gacctatcgt acaaaagcag actgccagca tacggctatg
    33781 attggttcct cactaggagg caatataccc agtttatcgg tttggaatac caagaccaaa
    33841 ttggttgctt gggcgttttt tcatctgcaa actggctcca ccaagaagcc tttaaccgct
    33901 atatcgagtg ccagaaacta tcgcctgacc agcgcatctt catctatgta ggaacagaag
    33961 aagcagatga tacagacaag accttgatgg atggcaatat caaacaagcc tatatcgact
    34021 cgtcgctttg ctattaccat gatttgatag cagggggagt acatctggat aatcttgtgc
    34081 taaaagttca gtctggtgcc atccatagtg aaatcccttg gtcagaaaat ctaccagatt
    34141 gtctgagatt ttttgcagaa aaatggtaag ttaagaaagg aaaaaacgaa atgcatattg
    34201 aacatcttag ccactggagt ggtcatctta accgtgaaat gtaccttaac cgttatggac
    34261 atggtgggat tccagttgtg gtctttgctt catcaggtgg tagtcacaac gaatactatg
    34321 attttggcat gattgatgcc tgtgcttcct ttatcgagga aggccttgtc cagttcttta
    34381 ccctatctag tttggatagt gagagctggt tggttacttg gaaaaatgct catgaccaag
    34441 cggaaatgca ccgtgcctac gaatgttatg tgattgagga ggccattctt ttatcaagca
    34501 caagacaggt tggtttgatg gcatgatgac gacaggttgc tctatgggag cctatcatgc
    34561 actcaatttc ttcctccagc atccagatgt ctttaccaaa gtgattgctc tcagtggtgt
    34621 ttacgacgca cgtttctttg tcggtgatta ctacaacgat gatgctattt accaaaactc
    34681 gccagtagat tatatttgga accaaaacga cggctggttt attgaccgtt accgtcaggc
    34741 agagattgtg ctgtgtacgg ggcttggagc ctgggaacaa gatggtttgc catcctttta
    34801 caagctcaaa gaagcctttg acaagaaaca aattccagcc tggtttgctg aatggggaca
    34861 tgatgtcgcc catgactggg aatggtggcg taaacaaatg ccttatttcc tcggtaatct
    34921 ctatttataa aaggagttac ctatgaatta ccttgttatt tctccctact atccacaaaa
    34981 ctttcaacag tttaccatcg aactagctaa taaaggcatc acagtcttgg gaattggtca
    35041 agagtcttac gagcaattgg atgagccctt gcgcaatagc ttgaccgagt attttcgtgt
    35101 tgataatctt gagaacatag atgaagtcaa acgtgcagtt gcttttctct tttataaaca
    35161 tggtccaatt gaccgcatcg agtctcacaa tgaatactgg cttgagctag acgcaacact
    35221 cagagaacaa ttcaatgttt ttggtgccaa accagaggat ctcaaaaaga cgaaatataa
    35281 gtctgaaatg aagaaacttt tcaaaaaagc aggtgttcct gtggtacctg gagctgttat
    35341 caagacggaa gcagatgttg atcaagcagt gaaagaaatc ggtcttccaa tgattgccaa
    35401 acctgataat ggagtgggag cagccacaac ctttaaactt gagacagaag acgatatcaa
    35461 tcacttcaag caagaatggg accattcaac cctttatttc tttgaaaaat ttgtcacttc
    35521 cagcgaaatc tgtacctttg acgggctcgt ggacaaggat ggaaagattg tcttctcaac
    35581 aacctttgac tacgcctata caccgcttga cctcatgatt tataagatgg acaattctta
    35641 ttatgtgctc aaggatatgg atcctaaact gcgcaagtat ggggaagcaa ttgtcaaaga
    35701 atttggtatg aaagaacggt ttttccatat tgagttcttc cgtgaggggg acgattatat
    35761 taccatcgag tacaataacc gccctgcagg tggttttacc attgatgttt ataactttgc
    35821 tcattccttg gacctctatc gtggctatgc agctattgtc gcaggagagg agttcccggc
    35881 gtcagacttt gaaactcagt attgtttggc tacttctcgc cgtgcaaatg ctcactatgt
    35941 ttattcagaa gaggatttgc ttgccaaata tagccagcag ttcaaagtta aaaaagtcat
    36001 gccagctgcc ttcgcggaac ttcaaggaga ttacctgtat atgctgacca ctccgagtcg
    36061 acaagaaatg gagcagatga ttgcagattt cggacaacgt caagaataag aactatcgga
    36121 ttaaggaaat taactccctt aatccttttg ttttgtctga taaaaaataa gagcatccca
    36181 acaaggtagc tatcataaaa cttgttcgat aactatttga agcaggatta ggtggtcaga
    36241 aattgaattt taatatttca attgagtcat agtattgtgt ttgcgtatcc ttaaatcagc
    36301 taaaaggatc catgacgaca cctatacgat atagttttca agataccaaa caagtctatt
    36361 aatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggtttc tcaaaacact
    36421 gttttgaggt tgtggataga actgacagag tcagtatcat atacctacgg caaggtgaag
    36481 ctgacgtggt ttgaagagat tttcgaagag tataaaatat tcaggtgacg catagatata
    36541 gttaattgaa gctttgtttg aaatctgata aaataatgat attactaagt tttaaaaact
    36601 aaagaaaagg gaagatatga ttacaggcga attaaaaaat aaaatcgatc agctgtggga
    36661 aattctttgg acagaaggaa acgcaaatcc tttaacaaat attgaacagt tgacttatct
    36721 cttatttatg aaagatttgg atagtgtcga gcttggacgt gaaagtgatg ctgaatttct
    36781 agggattcct tatgagggag tttttccaaa agataaacct gaataccgtt ggtcaacttt
    36841 taaaaatata ggagatgctc aggaagttta tcgtttaatg actcaggaga tttttccgtt
    36901 tattaaaaat ctcaaggggg atacagatga tacagccttt tcacgatata tgcgagaagc
    36961 tatttttcaa ataaataaac ctgctacgct tcaaaaggca atttctatct tagatgtttt
    37021 tccaactagg ggattagatg tagattttga taatgacaaa caaagtatta ctgatatcgg
    37081 agatatctat gaatatctgt tatcaaaatt gtcgaccgca ggtaaaaatg gacagttccg
    37141 tacacctcgt cacatcatcg atatgatggt tgagttgatg caaccgacta tcaaagatat
    37201 catctcagat cccgctatgg gttctgctgg cttcttagta tctgctagcc gttacttaaa
    37261 gcgtaagaaa gatgaatggg aaaccaatac agataatatc aatcattttc ataatcagat
    37321 gtttcatgga aatgatacgg atacgactat gttgagactt ggggcgatga acatgatgct
    37381 acatggagta gaaaatccac aaatcagtta ccttgactcg ctgtctcaag ataatgaaga
    37441 agccgataaa tatactttgg ttttagcaaa tcctcctttt aagggctcac ttgactacaa
    37501 ttcaacctct aatgaccttc ttgcaaccgt aaaaaccaaa aaaacagaat tactctttct
    37561 ttctcttttc ttgcgaactt taaaaccagg tggacgagca gcagttatcg tacctgatgg
    37621 tgtccttttt ggttcgtcta aagctcataa aggaattcgt caggaaattg tagagaatca
    37681 taagcttgat gctgtaatct caatgcctag tggtgtgttc aagccttatg ctggagtttc
    37741 aactgctatt ctcatcttta caaaaactgg taatggtggt actgacaaag tctggtttta
    37801 cgatatgaaa gcggatggtt taagtttgga tgataagcga caaccgatta gcgacaatga
    37861 tattccagat attatcgaac gctttcatca tcttgaaaaa gaagcagaac gtcagagaac
    37921 ggatcaatct ttctttgttc cagttgctga gataaaggaa aatgattatg atttgtctat
    37981 caataaatat aaagagattg agtatgaaaa agttgagtat gaaccaacag aggtcatctt
    38041 aaagaaaatc aatgatttag aaaaagaaat tcaagctggc ttggctgaat tagaaaaatt
    38101 actcaagtag ggaggtggct gtatgaaaaa agtgaagttg ggggaagtct tatctctaaa
    38161 aaaaggaaag aaagccactg tacttgctga acaaacaact ctaagccaac gttatattca
    38221 aatagatgat ttaagaaata ataataattt aaaattcact gaaagtttaa atatgactga
    38281 agcactccca gatgatattc taatagcatg ggatggtgct aatgcaggaa cagttggcta
    38341 tgggttatcg ggagctgttg gtagtacaat tacggtctta aaaaagaatg agcgatacaa
    38401 agaaaaaatt atatcagatt acttgggagt ctttttggaa agtaaatcgc agtatttacg
    38461 agatcattca acaggtgcaa ctattcctca tttaaacaag aatatattac ttgatttaca
    38521 attagaattg ctaggtatcg aagaacaaga gaacattatc tgtattctta atacgattaa
    38581 aaggcttatt actaaaagaa aatttcagtt agatgaacta aacttgctcg tcaaattccc
    38641 gatttaacga gatgtttggg gatcctttaa ataataacaa gaaatttgca gtaaaaacgg
    38701 gacaacagtg ttttaaattt tcaagtggaa aatttcttga taaacatgat agagtttttg
    38761 aaggttatcc tgcctatggt ggaaatggca ttgcttggaa aagtcgaaaa tatttaattg
    38821 ataatcctac tatcatcatt ggtcgtgtag gtgcatattg tggtaatgta agaactaccc
    38881 acggtaaggt atggataagt gacaatgcta tatatataaa agaatttaag aattccgatt
    38941 tcaatcttgt atttttatta gaattaataa aagtaattga ttttagtaaa tttgctgatt
    39001 tctcaggtca accaaagata actcaaaaac cattagaaaa tcagaaatat atcctccccc
    39061 ctctagccct caaaaatgag ttcgcagact ttgtagccct ggtcgacaaa tcacaattgg
    39121 caatccaaaa atctctggaa gaacttgaaa ctttgaagaa atctctgatg caggagtatt
    39181 ttggctgata ttctgccatt gtaattacgg taatgatttg ttataatact tcaaaggagg
    39241 aaatcagatg gtagtaaaaa caagaaaaca aggaaattca atcaccatta cgattccaag
    39301 tgaatttaat attccaagtg gtgttaaata cgaagcgaaa ttgttaccaa gtggtgagat
    39361 tatctttact cctgaagaat tggggcagca ggtttcttat gtatctgatg atgcctttga
    39421 cttaaattta gataaaatat ttgacgaata cgacgatgtt ttcaaagctt tggtggaaaa
    39481 atgacaatct atctgacaga aaagcaaatt gaaaaaataa atgctttagc aattcaacgg
    39541 tattctccaa atgagaaaat tcaaacagtt agttcttctg ccttaaatat gattgtgaac
    39601 ttaccagaac aatttgtctt tgggaagtct ctttatccaa caatttttga taaagcaacg
    39661 atactatttg tccaattgat aaagaagcat gtttttgcta atgctaataa aagaactgct
    39721 ttcttcgttt tggtcaaatt tttacaatta aacggctatc gtttttctgt aacggtagaa
    39781 gaagcagtaa aaatgtgtgt aaccatcgca gtagaagctt taactgatga aaaaatgaca
    39841 agctactcca aatgggtttc tgaacattct gttagagaaa aggtcaaaaa gtaacctagt
    39901 atgctggatt tgaatgagca caagaaaata aatgaacaga caatattaga attctgtaat
    39961 gcagaaactg atattgtctc tttttattga tgaataagaa agtgagaaat tatggaatca
    40021 aaagttacaa ttatcatgca agaaatgtta cctcttttaa ataatgaaca attactagcg
    40081 ttgagagaga gtttagaaca tcatctagta gacggaaaaa agcagcagaa gtattcgaat
    40141 aataacctgt tgcaactatt tattaccgcc aagcaggtag agggctgtag ctcaaaaaca
    40201 attcgttatt accagaggac gattgaaaac ttgtttaatg ctattaaaga gtctgtgaca
    40261 caactcacaa cagatgattt aaggagttat ttagcaaatt accagtctga aaaggattgt
    40321 agtaaggcaa atttagacaa tattaggcgt atattgtctt ctttttttgc ttggcttgag
    40381 caagaggaat atatcattaa aaatcccatt cgacggataa agaaaattaa gactgagcaa
    40441 aatgtgaagg aaacttatac tgatgaacat ttggaaatta tgcgtgataa ctgtgaaaat
    40501 ttgagagatt tggcaataat agacctacta gcatcgacag gtatgcgtgt aggggagctt
    40561 gtacagttga atcgttcaga tattgatttt gaaaacagag agtgtgttgt ctttggtaaa
    40621 ggaaagaagg agagaccagt atattttgac gctcggacga aaattcattt aagaaattat
    40681 cttaacgaca gaaaagatag tcaccctgct ctttttgtaa cgctagttgg aaaagcccag
    40741 agacttggaa ttgctggtgt agagattcgc ttaagaaagt taggagacaa actcggcata
    40801 caaaaggttc acccacataa gttcagaaga actttagcga ctaaggcaat tgataaaggt
    40861 atgcctatcg aacaagtcca aaaactgcta ggtcatagca agattgacac aaccttggcc
    40921 tatgccatgg tcaatcaaaa taatgtcaag cattcacacc aaaaattcat ctcttaaaag
    40981 caaatcccga tttaacgaga tgtttgggga aaataaaata tttgaaagca ttgataactt
    41041 atttgatatt atagatggtg ataggggcaa aaattatcct aaatcagatg agttgtttag
    41101 tgaggagtac tgtttatttt taaatacaaa gaatgttact aaaaacggat tttcattcga
    41161 tacaaagcaa tttatcacta aaacaaagga taaattactt cgaaaaggca aacttgagcg
    41221 ttatgatata gtcttgacaa caagaggtac tgttggaaat gtagcgtact acgatgaatt
    41281 aataaaatat aaacatttac gtataaattc aggtatggta atattacgtc ccaagacacc
    41341 aaatctaaat cagaaattta ttatccatgt tttaaggaat aataattata gtcgagtgat
    41401 atcaggaagt gctcagcctc agttaccaat tacaaaatta aaaaaaatac ttctccccct
    41461 ccccccacta gccctccaaa atgagttcgc agactttgta gtccaggtcg acaaatcaca
    41521 atttgcttgt gagatagcta taaaagtgtg gagaaatagc ttgaaattta gtataatata
    41581 gctaaactat ttgtttaaag tgagaaaaaa atgggaaatt ttagctttct tttaaaaaat
    41641 gacgaatatg aatctttttc aaaaccttgc attgaagctg agaatatgat tgctacatca
    41701 actgtggcta ctgcctttat ggcgcgtcgt gctttagagc aggctgtcca ttggatatat
    41761 agtcacgatt catatttaga agctccctat cgtgctactc tatcttcttt agtatgggat
    41821 gatgatttta gggatatcgt agattctgaa ctccacaagc agatagttct gttgattcgg
    41881 tggggaaacc atgctgctca tggtggtgaa attaaggaac gagaagcgat tttagctttg
    41941 catcatttgt atcagtttgt taattttatc gattattgtt acagcaatga gtttgtggag
    42001 cgttattttg atgagaagtg cttaccactt tcagcaaaca tcaaataccg agaaactcca
    42061 caatctatga taaagttaca agacagttta ccagaactgc ctgattttca tgaacagatg
    42121 gctgctcagt ccgtagaagt tcaagagact tatactgaaa aacgtgagac tgcagcgcaa
    42181 cggcaagatg tgcctttcca tattgatcaa ttatctgagg cagagacaag aaagctcttt
    42241 attgatatcg atctccgttt agcaggatgg atatttgaag aaaactgtcg tgttgagata
    42301 gccgttgatg gtctcaagca cggttcagga attggttact gtgactatgt actttatggt
    42361 aaaaatggga aaattttagc gattgtggag gctaaaaaag cctctgtcaa tccagaagta
    42421 ggggaagtac aggtcaaaga atatgctgaa gctttggaga aacatatcgg ctatcagcca
    42481 atttgcttta ttacaaatgg gttgaagcac tatatacttg atggtccgaa ccgccgccag
    42541 attgcaggct tttactctca agaagaattg caattagtga tggatagacg tcatcttcaa
    42601 aaaccgcttg aggatatttc tagtaaaatt agggacgata tttccgggcg tcactaccaa
    42661 aaacatgcca ttgcaagcgt ttgtgaagct ttctctaatc atcgtagaca ggcacttttg
    42721 gttatggcaa ctggggcggg gaaaactcgt acagcagttt ctctagttga tatcttatca
    42781 cgtcataact gggtaaaaaa cgttctcttc ttagccgata gaacttcctt ggttaagcaa
    42841 gcctatgatt cgtttagaaa attactccca gatctttccg tttgtaactt cttagaagat
    42901 aaagaaggag ctcaatcaag tcgtatggtc ttttcaactt atccgaccat gattggagcg
    42961 attagtggtc aagaagaagt aaatcaacgc ccttttactg ttgggcattt tgaccttatc
    43021 ataattgacg aatctcaccg ttctatttat cagaaataca agtccatttt tgattatttt
    43081 gatgcaagaa ttgtaggctt aacagctact ccgcgtcaag atttagataa aaacacctat
    43141 ggattcttta atttggagaa tggggttcca acatatgcat atgatttgga agaggctgtt
    43201 aaagacggat atttagtagc ctatcattct atcgaaacca aactgaaact acctacggat
    43261 ggtctacatt atgatgattt gtccgaagaa gaaaaggaac attttgatag caaatttgaa
    43321 gacgatagct gtgaaaaaga tattgatggg agtgtattta attcctttat tttcaataaa
    43381 agtacagtag aaattgtttt aaatgaactc atgacaagag gaattcagac agcctcgggt
    43441 gatgaaattg gtaaaactat tatttttgct aaaaatcatg atcatgcgga atatatcaga
    43501 ggtattttta acaaccgcta tcctgaaaaa gggagcgact atgctcaggt gattgattat
    43561 agtattaagc attatcagac cttgattgat gattttaaaa ttaaggagaa gtatcctcaa
    43621 attgcgattt ctgtcgatat gttagataca ggtattgatg taccagaggt tgttaattta
    43681 gtcttcttca agaaagtacg ctctaaaact aagttttggc agatgattgg tcgaggaacc
    43741 cgtctatgta aagatttatt tggacctgag caggataagg aaaacttctt ggtatttgat
    43801 tatggggaca attttgatta ttttcgtgca gatccaagag atggagaggg tcgtcacatt
    43861 gtttcgctga ctcagcgttt atttaatatc aaagtggact tgattcgaga acttcaggga
    43921 ctccaatacc aagaagatca gtttgcgaga gcataccgtc agcagcttgt ctcggaactt
    43981 caaggtcgta tagagagctt aaatgagttg gacttcaggg ttcgtatggt tttagataca
    44041 gtttatagct ataagaaatt ggaaagttgg cagaatctaa ctgctgttac aagtgaaacc
    44101 attcaaaaaa atctctctcc gcttttattt gatgaagata aagaagatga gatggcgagg
    44161 agatttgatt tgtggttgct tcatattcag ttggggcaac tgacagctaa atcttccact
    44221 gttcatattt cccaagtgat gaagacggct agagctcttt ctgctattgg caatatcccg
    44281 caggtttttg agcaggctga aattatcagg aaagtacagg agcctgaatt ttggaaagaa
    44341 gttaacttgt ctgatttgga aaaaattcgt cttgctattc gagatttatt acagtttttg
    44401 gataaaacag accgtaaacc ctactatgtt aactttgaag atcgtatact ctccactgtt
    44461 cacgagacca cagcattttt gcaggtcaac gatcttcggt cttacaatga aaaagttgag
    44521 caatatttga aaactcatct ggatgaggag tccatttcta agctatacca taataaaaag
    44581 ttgacatctg atgatatgct tgcacttgaa aaattgcttt gggaaaaatt aggtagtaaa
    44641 gcagactacc aaagtcatta tgaaaataag gcaattccga gattggttcg tgagattatt
    44701 ggcttagata gagagtctgc caatcgtatt ttttctaaat ttttgtcgga tgagaatctt
    44761 aatgccaggc agatttcatt tgtaaaattg attgtagact acattgtaga aaatggtttt
    44821 ttagagacga aagtgttaac gcaagagccg tttaaatctt atggttctgt tcaactactc
    44881 ttccaacacc aactaccagt acttcgtaat attgttcaaa tcattgaact tatcaataat
    44941 cgagctggag aagcggctta aattctaaag tgattgccat gctgagactc atttaaaatt
    45001 aaaaagagta gaaatttatg ctatatatga gaagttttat taggaagaat gtcatcgttt
    45061 tcctagaata cagtatcagt tgttaagtgg ttgataaatt tcaaagtaga tacttgtacc
    45121 acgatgtttg ttgatcgagt tattaacaaa agagctactt tgattttaaa gaaatagaaa
    45181 acaaaaagct gagcaagaat tcaattgcag gagaaaatga aataatactc aatgaaaatc
    45241 aaagagcaaa ctaggaaact agctgcaggc tgctcaaaac actgttttga ggttgtagat
    45301 aagactgacg aagtcagctc aaaacatggt tttgaggttg tagatgaaac tgacgaagtc
    45361 agtaaccata tatacggcaa ggcgacgttg acgcggattg aagagatttt cgaagagtat
    45421 aaatcttctt aggataaagc aaaacgcata gtatcaaggg ttttcaacac ttgatactat
    45481 gcgttttctg atgttaaaga ctttctacca ggttttttaa aagcataatt gttagttgta
    45541 gtcatttatt attcttcaaa gaaaaatggt ggggcgaatt ttttcagttc ttcaaagcac
    45601 ttttgagcag tatctgcatc ttcacagatg ataagacaga catcattacc acaaagggta
    45661 gcgatagcgt cagggaagct caaagtatca atgatagaac caaaggattg agccagtcca
    45721 ggaagggttt ttagtaggac ttggtgttga actgggcgca tccagacaag ggcgtcttcc
    45781 atgtagagtt cgagacgttt ttcccatttt gagatggaac cattgttaag aacataataa
    45841 gcgctatctt cttcgcggac ttttgatagg ttcatatttt tgatgtcgcg tgagagggtt
    45901 gcctgggtta cttgaatgtc gttctcagca agaagggctt gcaactcagc ctgtgtatga
    45961 atcttgtttt ttgtgataag agcgcgtata agttggtggc ggtgttctga tttattcata
    46021 ataatgtaac tccttttagc aaggtaaggt aagcatggac tgagcgaggt cgacagtcaa
    46081 gtggtagtct gtattgtcac ggatggtgat ttcaaagtca gtagtataga ggactaaacg
    46141 gagagtgtct ccttctttta gcttgtaaat agttggctgc agttcaaatt gaacgtccat
    46201 ccattcatct gcagtaatat cctctactaa cagtaaatca tttctatttt gtaaattaag
    46261 gtaacctttt gtcacgactc gttgtgcctc tggtctaaat ggcaattcac agagattttc
    46321 caacatgtga tagcgaccgt tgtcaatggt tctagcactt aaaatagctg gataaggttg
    46381 taggtattta ttttgcccaa attctagcag ttgggcagat aagagcccct tgtttgtact
    46441 ggatttgata cgaagattga gctgagcgcg accgtttagg tggagatctt tagtcacagg
    46501 aaggttaata gtaatctgat tagctttccc ttgatagagc tctgtattga agatttggta
    46561 tgtcttacca tagcgctcaa aatccttatc tgggtactgg ttttgaatag cttgctcttc
    46621 ttgaccaagt gagaaggttt cacagttttc ttgcccaccg aagttatcaa gtgataacca
    46681 agtctgtgga gctgtattgt cctgccagat aacagtagga agttgaaagt ctgtttcctg
    46741 tcctagtaat ttcttggtca ataaggcatt tatggactca cggaagtcaa ttgattgcca
    46801 attgttcatg taaacatggg caccattatg gaaaaagaga tgcttgtgta tatgagtagg
    46861 aagagcatgg aacatctggt aaacatgaag tggtttgaca ttccaatcct gagaaccatg
    46921 agtaaagaca acctctgcct ttactttatg ggcattgagc agataattgc ggtcatgcca
    46981 aaactgattg tagtccccag tttttcggtc tagctgagct ttcacttttt ctaagtcagc
    47041 ttggtgagct tcattgccac ggatatagtc gccagctaag agattacgag aataggttaa
    47101 ctcagcaagg gagtcaaagt cctcacctgg ataaccacct gggctagtca ccagaccgtt
    47161 ttcacggtag tagttgtacc atgatgaaat tcctgcctcg gcaatgataa cttctaaacc
    47221 atcgactcct gtagtcgcaa gaccattgga catggtacct agataggaaa gtcctgttgt
    47281 agcaactttt ccgtttgacc aatcagcctt gacttgacgc tggcgcgtgt gatcagtaaa
    47341 ggcacggcaa cggccgttaa gccaatcgat gacattttta taagcctcga tttgctggta
    47401 gtctccatta gtcatgaaac ctgtcgagtc tttggtacca acacctgaga catagagatt
    47461 ggcaaagcct ctcggaagga agtagtcgtt tagtgtatag ctagagttga tgtgagttag
    47521 cttttcctca gcctctgcta taagctcagc tttaccttgg ggttggacga gatttagttg
    47581 aggtttctct agctcaatct tgtgaggaag tttaacctca agctcgccct ccatcttgta
    47641 gagagccttg tcactagcct tgtcattggt tccctgatga taagggctgg ctgtcatgat
    47701 ggcagggatt tttccatcaa aacgagggcg aataatgcta acctttacta ggtctgatag
    47761 ccctttttgg tcagtatcga cacgagactc aacgtaaacg acttcacgaa tgacatcctg
    47821 gttagaaaaa gtagccaaac tcttgccgtt aaagtagtgg tagtcattat cctccggaat
    47881 aagaccatca ctaacaagtt ggtcgataag agtatttcct tttttggtgc gagtattgag
    47941 taactgatag agattttcaa tcaagtcacc atatataatg ggaaatccag tttctttacg
    48001 aaaaacgtca ctatcttcga agtcaaccaa ataagaaaag cctaaaagtt gaaaagcaac
    48061 agtataaaaa atatctgctg tcagttcatc ttctgattga aaaaatgtca gcaggtctgt
    48121 ttttttatca gctgctagga tagaaagtgg gtagttggtg tcttgataag tgaaaaagaa
    48181 acgacgtaaa aaggtttcaa gtgagtcttt gtgattggct gtattttgta aatcaaagcc
    48241 acattttttt agttcagata agacattttc ttttggaaaa ttgatataac tatattgatt
    48301 aaaacgcata gaacctccat atagaatgac agttaaggtt attatatcaa aaaaaaagca
    48361 gaaagggaat tgttaacttc aaaaggaaat aatccaataa aaatgaataa agtactaaat
    48421 tcaatataga gaacagagta acaataagaa taaatagata gggtataaaa gttctaggag
    48481 atttatatta tatgctttct atttttatat acaatatagt ataaatataa aaatgatgac
    48541 aaaaatacaa atgaatagaa aataaattag taagctgatg aaatttttct caagagaagc
    48601 catttatagg tgaaaatggt ataatatagt gagaaggata gaggagaagt gtaaattgat
    48661 cgcacaacta gatacaaaaa cagtctatag ttttatggaa agcgtcattt cgatcgaaaa
    48721 gtatgtgaga gcagctaaag aatacggcta cactcatttg gctatgatgg atattgacaa
    48781 tctttatggc gctttcgact ttctagagat tacaaaaaaa tacggcattc atcctttgct
    48841 agggcttgaa atgacagtgt ttgtagatga tcaggaagtg aatttgcgct ttttagctct
    48901 atctagtgtg ggctatcagc agttgatgaa gctttcgaca gccaagatgc agggggagaa
    48961 aacttggtca gtcctgtccc agtacctgga ggatatcgcg gtcattgtgt cttattttga
    49021 tagagttgag tcgttagaac taggctgtga ttactatata ggggtttatc cagaaacact
    49081 agcaagcgaa tttcatcatc ctatcttacc tctttatcgg gtcaacgctt ttgaaagcag
    49141 ggatagagaa gttcttcaag ttttaacagc gattaaagaa aatctaccgc tcagagaagt
    49201 tcccttgcgt tcgagacaag atgtctttat atcagcaagt tctttagaga aactattcca
    49261 agagcgtttt ccgcaagctt tggacaattt agaaaagctt atttcaggca tttcttacga
    49321 cttggatact agtctgaaac tgcctcgttt taatccagct agaccagcag tagaggagtt
    49381 gagagagcgt gctgaactgg ggcttgttca gaaggggttg actagtaaag aatatcaaga
    49441 tagactagac caagaattgt ctgttattca tgatatgggc tttgatgatt atttcttggt
    49501 tgtttgggat ttgttgcgtt ttggacgatc gaatggctat tatatgggaa tgggaagggg
    49561 ttctgcagta ggcagtttgg tttcttatgc cttagacatc acggggattg acccagtaga
    49621 gaaaaatctg atttttgaac gctttcttaa tcgtgaacgc tataccatgc ctgatattga
    49681 tattgatatc ccagatattt atcgtccaga ttttatcaga tatgttggta ataaatatgg
    49741 tagtaaacat gcggcacaaa tcgttacttt ttcaaccttt ggagccaagc aagctcttcg
    49801 agatgtcttg aaacgctttg gtgtgccaga gtatgaatta tctgcaatta ctaagaaaat
    49861 cagttttcgt gacaatctta agtcggccta tgagggcaat ctccagtttc gtcagcaaat
    49921 caatagtaag ttagaatacc aaaaagcttt tgagattgct tgcaagatag agggctatcc
    49981 aagacaaacc tctgtccatg cggctggtgt tgtaattagt gaccaagatt taaccaacta
    50041 tattcctcta aagtatggtg atgaaattcc actgactcag tatgatgctc atggagttga
    50101 ggctagcgga cttttgaaga tggactttct gggactacga aatttgacct ttgtccagaa
    50161 gatgcaagag ttgcttgctg aaatagaagg tattcacctt aaaattgaag aaatagattt
    50221 ggaagacaaa gaaacgttag atttatttgc ctctggaaat acaaaaggta tctttcaatt
    50281 tgagcaacca ggtgccattc gtctgcttaa gcgtgtgcaa ccagtctgtt ttgaagatgt
    50341 cgtcgcgact acttctctaa atcgaccggg tgctagtgac tatatcaata attttgtggc
    50401 aagaaagcat gggcaggaag aagtgactgt tctggatcca gtactggagg atattttggc
    50461 tccaacctac ggcataatgc tctatcagga gcaggttatg caggttgccc agcgatttgc
    50521 cggatttagt cttgggaaag ccgatatttt gcgtcgggct atggggaaaa aggatgcctc
    50581 tgccatgcat gagatgaggg tttcctttat tcaaggttca ttagaagctg gtcatactgt
    50641 ggaaaaagca gagcaggtct ttgatgttat ggagaagttt gcaggttatg gttttaacag
    50701 gtcacacgcc tatgcctact cagccttggc cttccagttg gcttatttta aaacacatta
    50761 tccagccatt ttttatcagg tcatgttaaa ttcttccaac agtgattact taatagatgc
    50821 acttgaagca ggttttgaag tagcctctct atccatcaac accattccct atcacgataa
    50881 aattgccaac aaggccatct atctaggttt gaaatccatt aaaggagtca gtaatgattt
    50941 agctctctgg attattgaaa atagacctta ttctaacatt gaagatttta tagctaaatt
    51001 acctgagaat tatctgaaac ttcctctgct agaacctttg gtaaaagttg gtcttttcga
    51061 ttcatttgaa aaaaatcgtc aaaaagtatt taataattta gctaatctat ttgaatttgt
    51121 gaaagagttg ggaagtttgt ttggagatgc tatttatagt tggcaggaat cggaagattg
    51181 gacggaacaa gaaaaatttt atatggaaca agagctttta gggataggtg tcagcaaaca
    51241 tccactacaa gctattgcaa gtaaggctat ttacccgatt accccaatcg gaaatttgtc
    51301 agaaaatagc tatgctatta tcttggttga agttcagaaa ataaaagtga ttcgtaccaa
    51361 aaagggtgaa aatatggcct tcttacaggc agatgatagt aagaaaaaat tggatgtcac
    51421 tctcttttca gacttatatc gtcaggttgg acaggaaata aaagagggag ccttctacta
    51481 tgtaaaagga aaaatacaat cacgtgatgg ccgtctgcaa atgattgcac aagaaataag
    51541 agaagcagtt gctgaacgct tttggataca ggtgaaaaat catgaatcgg atcaagaaat
    51601 ttcacgcatt ttagaacaat ttaaaggccc aatcccagtc atcatccggt atgaagagga
    51661 acagaaaacc atcgtttctc cccatcattt tgtagctaaa tccaatgaat tagaggagaa
    51721 attgaatgaa atcgttatga aaacgattta tcgctaaaaa tacggaaaat agaagaattt
    51781 taaaatcaaa tgtgatataa tcaagaagaa tgttaaaaga aaaaggagca taaaccaata
    51841 tgaaacgtat tgctgttttg actagtggcg gagacgcacc tggtatgaac gctgccatcc
    51901 gtgcagttgt tcgtcaagca atttcagaag gaatggaagt gtttggtatc tatgacggat
    51961 atgctggtat ggttgccggt gaaattcatc ccctagatgc agcttcagta ggggacatca
    52021 tttctcgtgg tggtactttt cttcactcag ctcgttaccc agagttcgct caacttgaag
    52081 ggcaacttaa agggattgag caattgaaaa aacacggaat tgaaggtgta gttgttatcg
    52141 gtggtgacgg atcttaccac ggcgctatgc gtttgactga acatggcttc ccagctattg
    52201 gtcttccagg tacaatcgat aacgatatcg ttggtactga ctttacaatc ggttttgaca
    52261 cagcggttac tactgccatg gacgctatcg ataagattcg tgatacatca tcaagtcacc
    52321 gtcgtacttt tgtaatcgaa gttatgggac gtaacgctgg tgatatcgct ctttgggctg
    52381 gtattgcaac tggtgctgat gaaatcatca tccctgaagc aggcttcaag atggaagata
    52441 tcgtagcaag catcaaagct ggttatgaat gtggtaaaaa acacaatatc atcgtcttag
    52501 ctgaaggtgt gatgtcagcg gatgaatttg gtcaaaaact taaagaagct ggagatacaa
    52561 gcgaccttcg tgtaacagaa cttggacata ttcaacgtgg tggttctcca actgcgcgtg
    52621 accgtgtttt ggcgtcacgt atgggtgcac atgctgttaa acttcttaaa gaaggtatcg
    52681 gtggtgttgc ggttggtatt cgtaacgaaa aaatggttga aaatccaatt cttggtactg
    52741 cagaagaagg ggcattgttt agccttactg cagaaggtaa gattgtggtt aacaacccac
    52801 acaaagccga tattgagcta tctagcttga ataagagctt gtcataattt acaatttagt
    52861 taataagacc aaaaaggtca tatatataaa ggagtcacaa aaatcatgaa caaacgtgta
    52921 aaaatcgttg caactttggg tcctgcggta gaaatccgtg gtggtaaaaa attcggtgag
    52981 gacggatact ggggtgaaaa acttgatgtt gaagcttcag ctaaaaacat tgctaaattg
    53041 attgaagctg gtgctaacac attccgattc aacttctcac acggcgacca ccaagaacaa
    53101 ggtgagcgta tggcaactgt taaacttgcg gaaaaaattg caggtaaaaa agttggtttc
    53161 cttcttgata caaaaggacc tgaaatccgt acagaattgt tcgaaggtga agctaaagaa
    53221 tattcataca aaactggtga aaaaattcgt gttgcaacta aacaaggaat caaatcaact
    53281 cgtgaagtga ttgcgttgaa cgttgctggt gctcttgata tctatgatga tgttgaagtt
    53341 ggtcgtcaag ttttggttga cgatggtaaa cttggtcttc gtgtggttgc taaagatgat
    53401 gcaactcgtg aatttgaagt tgaagttgaa aacgatggta tcatcgctaa acaaaaaggt
    53461 gtgaacatcc ctaacactaa aattcctttc ccagctcttg ctgaacgcga taacgacgat
    53521 atccgtttcg gtcttgaaca aggtatcaac ttcatcgcaa tttcattcgt acgtactgca
    53581 aaagatgtga acgaagttcg tgcaatctgt gaagaaactg gaaacggaca tgttcaattg
    53641 ttcgctaaaa tcgaaaacca acaaggtatc gataacttag acgaaatcat cgaagcagct
    53701 gatggtatta tgattgctcg tggtgatatg ggtatcgaag taccgttcga aatggttcca
    53761 gtttatcaaa aaatgattat caagaaagtc aatgctgcag gtaaagttgt tatcactgca
    53821 acaaacatgc ttgaaacaat gactgaaaaa ccacgtgcaa ctcgttcaga agtatcagac
    53881 gtattcaacg ctgttatcga cggaactgac gctacaatgc tgtcaggcga gtctgcaaac
    53941 ggtaaatacc cactcgagtc agtaactaca atggctacaa tcgacaagaa cgctcaagct
    54001 cttcttaatg aatacggacg tcttgattca gattcatttg agcgtaactc taagacagaa
    54061 gtaatggctt ctgctgttaa agatgctact aactcaatgg atatcaaatt ggttgtaact
    54121 cttactaaga caggtcatac tgcacgtttg atttctaaat accgtccaaa tgctgacatc
    54181 ttagcattga catttgacga attgacagaa cgtggcttga tgttgaactg gggtgttatc
    54241 ccaatgttga cagatgctcc atcttcaact gacgatatgt tcgaaatcgc tgaacgtaaa
    54301 gcggtagaag caggtctcgt tgagtcaggc gatgatatcg ttatcgttgc tggtgtgcca
    54361 gtaggagaag ctgttcgcac aaacacaatg cgtatccgca cagtacgtta agaaaaatat
    54421 aaaaacctat catatccagc tttatagcct gtatgatggg ctcttttttt gtccaggggg
    54481 caaaaagggg gcaaaacttt cataatggat t
//
LOCUS       DAVHKZ010000009        50424 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000009 DAVHKZ010000000
VERSION     DAVHKZ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50424
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.009"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            78..167
                     /locus_tag="VVO74_000685"
     tRNA            78..167
                     /locus_tag="VVO74_000685"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:114..116,aa:Ser,seq:tga)
     gene            178..251
                     /locus_tag="VVO74_000686"
     tRNA            178..251
                     /locus_tag="VVO74_000686"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:212..214,aa:Met,seq:cat)
     gene            255..327
                     /locus_tag="VVO74_000687"
     tRNA            255..327
                     /locus_tag="VVO74_000687"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:288..290,aa:Phe,seq:gaa)
     gene            340..420
                     /locus_tag="VVO74_000688"
     tRNA            340..420
                     /locus_tag="VVO74_000688"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:374..376,aa:Tyr,seq:gta)
     gene            425..495
                     /locus_tag="VVO74_000689"
     tRNA            425..495
                     /locus_tag="VVO74_000689"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:457..459,aa:Trp,seq:cca)
     gene            510..582
                     /locus_tag="VVO74_000690"
     tRNA            510..582
                     /locus_tag="VVO74_000690"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:543..545,aa:His,seq:gtg)
     gene            593..664
                     /locus_tag="VVO74_000691"
     tRNA            593..664
                     /locus_tag="VVO74_000691"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:625..627,aa:Gln,seq:ttg)
     gene            674..757
                     /locus_tag="VVO74_000692"
     tRNA            674..757
                     /locus_tag="VVO74_000692"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:708..710,aa:Leu,seq:caa)
     gene            complement(868..1599)
                     /locus_tag="VVO74_000693"
     CDS             complement(868..1599)
                     /locus_tag="VVO74_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU5694741.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYLI
                     DGDVTNSKTIPVLYYDTITQKYHFL"
     gene            complement(1592..1828)
                     /locus_tag="VVO74_000694"
     CDS             complement(1592..1828)
                     /locus_tag="VVO74_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HEU5694742.1"
                     /translation="MNNVVTTQISIQLSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWVECGKKATSHEEMMRRYG"
     gene            complement(2044..2481)
                     /locus_tag="VVO74_000695"
     CDS             complement(2044..2481)
                     /locus_tag="VVO74_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU5694743.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVATDEE
                     KAVAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
     gene            complement(2522..3655)
                     /locus_tag="VVO74_000696"
     CDS             complement(2522..3655)
                     /locus_tag="VVO74_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU5694744.1"
                     /translation="MAIRKGKDGNWVVDISNGFDPITLKQRRLVRKGYKTKKEAIEAE
                     HYLRSVELKERFYGAKITIPILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     DNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYSSN
                     PAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAETRRIVINKKLSQELQDWKKRQKHL
                     LEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            complement(3659..3862)
                     /locus_tag="VVO74_000697"
     CDS             complement(3659..3862)
                     /locus_tag="VVO74_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HEU5694745.1"
                     /translation="MIATVTKNDLIALGFFEGTSKRIIRQGKELLITRGFTVYQNKRI
                     GTIPATIATELLVFDVQNSTLKE"
     gene            complement(3876..4658)
                     /locus_tag="VVO74_000698"
     CDS             complement(3876..4658)
                     /locus_tag="VVO74_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HEU5694746.1"
                     /translation="MTSYNKKIVRTSSYIEIWEYEKPIFSKGKSILDTNTENKEKAKR
                     RTFDELTPLEQEQRLERMKKTRLEAKWNLLRLVDCNFDDTTSFLTLTTKENISDRNHF
                     KDSLKTFIKRFNYHIFNTKKSKLKYIAVLERQKRKAWHSHILLFSVPYIPHKQLLELW
                     GHGAVWINKVDVDSKENRGRYVTKYFEKGIGQELLENFGKQAYFSSRNLKKPDEDKFY
                     TYEDFNYDSSVVLYETEYTSKVYKYGQYFDNHVKYKKIRLDE"
     gene            complement(4842..5615)
                     /locus_tag="VVO74_000699"
     CDS             complement(4842..5615)
                     /locus_tag="VVO74_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU5694747.1"
                     /translation="MKTLLIGDLHLKSQLILPIVDKIIQTHNIKRIIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYSWKIDKEQNGIDVINLIGNHDAYYLLGEQAPFSIQNLEVFFAV
                     KELLQDLKLQIAYQLDDYLVSHAGFNLIFDPKEWHFNLYTKEYEEELDILAYTIGPMR
                     GGKALGGSPLWAHFRELELLPNQDFPKQIVGHTPKESIDISKNVIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYDQGHLEIISTNWATDETLKQLSKPQI"
     gene            complement(5659..6429)
                     /locus_tag="VVO74_000700"
     CDS             complement(5659..6429)
                     /locus_tag="VVO74_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU5694748.1"
                     /translation="MAIYYSVSDIHGHYNEFIKSLNKIDLSDKQSKLILLGDYIDYGS
                     QSFQVISKIIELEKIYPKQIITLFGNHEEWFYDWLILDNPTASAFPETIKSFFSTEEL
                     NYILKTNPNNFETGVRNEIRNNDKYIPFINWFQKRYEDSRYFETENQIFVHAGIDEEA
                     NNLWKDLTSPEIFTNKFPITTGRFYKDIISGHFASWEVAKDKSYLGKIYHDSKSHYFI
                     DGDVKNSKTIPVICYDTVKKSYQYSKNTSLLPKKFDRA"
     gene            complement(6448..6837)
                     /locus_tag="VVO74_000701"
     CDS             complement(6448..6837)
                     /locus_tag="VVO74_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694749.1"
                     /translation="MQIFTYNDFLKDKEIVTFEQAEIILDELIKSSNIYDPEFQAYWK
                     ELIEYSAKYAEMRGKWRILTKEEQDTLDDTRTNIHNRIRDNLISIRGLAQINNKDTSW
                     FDKFHNDRKRMGDFANYINYIYAVNSR"
     gene            complement(6875..7189)
                     /locus_tag="VVO74_000702"
     CDS             complement(6875..7189)
                     /locus_tag="VVO74_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694750.1"
                     /translation="MKLNDFLKPELLGNKFIAVKGYTEVLDRETNKPVALRLNVSIQD
                     EDSDFFMEMIQVKVNTLSPTASVQEMANNKTCPVTLKDLNVGQYNGNLWFSCSNVILI
                     TK"
     gene            complement(7279..8601)
                     /locus_tag="VVO74_000703"
     CDS             complement(7279..8601)
                     /locus_tag="VVO74_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEU5694751.1"
                     /translation="MFKLRQSADLTRNNIISCYKLKIMHWLILSISACILFSTIVNIR
                     APTFVQILFIFLGGFIIYKIHLKIKIFRYDLEHYLIIRESLLYVLHTNRLYTTSKDGS
                     GYEKIVRSAVLEYEIDRQKGHVLIKALITGDEFSKKVQSLDDVLSDVLELELEEKIIR
                     PSFIEYHFYYIKPKRLVLQSHSQRQEIDSLDIDLGYGVNYNPVKCSHILVSGGTGSGK
                     SVLISVLILEFLKRQSTVYIADPKNSDLGSLSHYFGNKYVATTPNNIARIVRVVVEEM
                     QERYQVMRDNFQYGSNFTNHGFKPVWLIFDEMGAFQATGSDKKSREIITEVMDGIKQI
                     ILLGRQSGIFILVSAQQVNASTTLSTELRDNLGLRIALGANSSEGYHMVFGSATPDKL
                     KPIEEKGSGYLYIQGSGKESAQYWESPYLDTTQFDFIKELQLYVTKSK"
     gene            complement(8607..8825)
                     /locus_tag="VVO74_000704"
     CDS             complement(8607..8825)
                     /locus_tag="VVO74_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694752.1"
                     /translation="MSDNLKAYLFLLGFVILAGIAIFIFPQGHFFSNSILILGCIPLL
                     ISTYYFAKIKLLGFYELLKELLDKIKGI"
     gene            complement(8865..9620)
                     /locus_tag="VVO74_000705"
     CDS             complement(8865..9620)
                     /locus_tag="VVO74_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU5694753.1"
                     /translation="MIQLTASTWNINLRSRKGKQIPEMIAQELAQQNSDIICLTEYVK
                     TDNHSQFCSSLQTNGYTIFEDVRTIDFGNEILIAIKSDLVNDCQVITIDNDDNNPNFL
                     HVRVTIEGQELNIIGVRIKIGGENVFEDFKHRKTQLDKLIFNLPIHENTIILGDFNNG
                     FFKQNDDTHSYQGKPREFYSYPLLKSEMNKAGLTVHTPSEENSWKYCKLDHIIGNIPI
                     SNVCYSWRFLENPDYQNKVGFPDHAILSATISL"
     gene            complement(10049..10552)
                     /locus_tag="VVO74_000706"
     CDS             complement(10049..10552)
                     /locus_tag="VVO74_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694754.1"
                     /translation="MTQFQVRISGEAAYYLRMLKEKYETSEGINITKATILTRAFQNS
                     KTVTNWTKVVQDNSISLKNIYPVEEKELKLNVALSDEVAEGIKKYKEILPSATNTQSV
                     TLGVCVKFLLKAELMTQLNHDISEPEKDFDKKFSILEKQLLEIVAPVNHKLLSDTIWN
                     FKNNFIK"
     gene            10981..12258
                     /locus_tag="VVO74_000707"
     CDS             10981..12258
                     /locus_tag="VVO74_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEU5694755.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKIDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFSLNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            12334..13818
                     /locus_tag="VVO74_000708"
     CDS             12334..13818
                     /locus_tag="VVO74_000708"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU5694756.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGETVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNMQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQVAVEAYLGL"
     gene            13879..15159
                     /locus_tag="VVO74_000709"
     CDS             13879..15159
                     /locus_tag="VVO74_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU5694757.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            15163..15783
                     /locus_tag="VVO74_000710"
     CDS             15163..15783
                     /locus_tag="VVO74_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU5694758.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLDPEKTY
                     YIGDRTLDVEFAKNSGIQSINFLESSFEGNHRIQALADISRIFETK"
     gene            15949..17127
                     /locus_tag="VVO74_000711"
     CDS             15949..17127
                     /locus_tag="VVO74_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU5694759.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVAPSTGTSVPEEQTAETTRPVEEVAPQATTLAEKQETQVSSQTESAVEATTMP
                     VEEKATETTATSSEAKEVASSNGATAAVSTYQPEETKTISTTYEAPAAPDYAGLAVAK
                     SENAGLQPQTAAFKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIA
                     EYAIQNMASRGISYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG
                     "
     gene            17640..17978
                     /locus_tag="VVO74_000712"
     CDS             17640..17978
                     /locus_tag="VVO74_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU5694760.1"
                     /translation="MTRYQILLFLLEHSLCNQMAVQERLKIDQAALTRNFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            17989..18357
                     /locus_tag="VVO74_000713"
     CDS             17989..18357
                     /locus_tag="VVO74_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEU5694761.1"
                     /translation="MSIITIILTTIVAWEHFYIFYLESIATQSDATSRVFNMEREELA
                     HPSVSLLFKNQGIYKALLGVCLLYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            18486..19082
                     /locus_tag="VVO74_000714"
     CDS             18486..19082
                     /locus_tag="VVO74_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU5694762.1"
                     /translation="MSPFEAIKGLPAEIHGAEVRWLEVPTVFHKSAQVLEEEMNRYQP
                     DFVLCIGQAGGRTSLTPERVAINQDDARTSDNEDNQPIDRPIRPDGASAYFSSLPIKA
                     MVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVKAGFMHIPYMMEQVVNR
                     PTTPAMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(19110..19967)
                     /locus_tag="VVO74_000715"
     CDS             complement(19110..19967)
                     /locus_tag="VVO74_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU5694763.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            20097..21239
                     /gene="tgt"
                     /locus_tag="VVO74_000716"
     CDS             20097..21239
                     /gene="tgt"
                     /locus_tag="VVO74_000716"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU5694764.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            21340..23157
                     /locus_tag="VVO74_000717"
     CDS             21340..23157
                     /locus_tag="VVO74_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU5694765.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            23310..24461
                     /gene="nagA"
                     /locus_tag="VVO74_000718"
     CDS             23310..24461
                     /gene="nagA"
                     /locus_tag="VVO74_000718"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU5694766.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            24624..25682
                     /locus_tag="VVO74_000719"
     CDS             24624..25682
                     /locus_tag="VVO74_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU5694767.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            25833..26198
                     /locus_tag="VVO74_000720"
     CDS             25833..26198
                     /locus_tag="VVO74_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU5694768.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            26274..27215
                     /locus_tag="VVO74_000721"
     CDS             26274..27215
                     /locus_tag="VVO74_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU5694769.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            27163..28179
                     /locus_tag="VVO74_000722"
     CDS             27163..28179
                     /locus_tag="VVO74_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU5694770.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            28181..28507
                     /gene="comGC"
                     /locus_tag="VVO74_000723"
     CDS             28181..28507
                     /gene="comGC"
                     /locus_tag="VVO74_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEU5694771.1"
                     /translation="MKKMMTFLKKAKVKAFTLIEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQADGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            28500..28904
                     /locus_tag="VVO74_000724"
     CDS             28500..28904
                     /locus_tag="VVO74_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU5694772.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            28909..29169
                     /locus_tag="VVO74_000725"
     CDS             28909..29169
                     /locus_tag="VVO74_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694773.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVNINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            29132..29593
                     /locus_tag="VVO74_000726"
     CDS             29132..29593
                     /locus_tag="VVO74_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU5694774.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            29571..30017
                     /locus_tag="VVO74_000727"
     CDS             29571..30017
                     /locus_tag="VVO74_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU5694775.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKNQKRSLKRKRIPSQFNYNALNPE"
     gene            30120..30714
                     /locus_tag="VVO74_000728"
                     /pseudo
     CDS             30120..30714
                     /locus_tag="VVO74_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            30775..31728
                     /locus_tag="VVO74_000729"
     CDS             30775..31728
                     /locus_tag="VVO74_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU5694776.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            31779..32969
                     /locus_tag="VVO74_000730"
     CDS             31779..32969
                     /locus_tag="VVO74_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU5694777.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADVIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            33118..33489
                     /gene="rnpA"
                     /locus_tag="VVO74_000731"
     CDS             33118..33489
                     /gene="rnpA"
                     /locus_tag="VVO74_000731"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU5694778.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            33464..34288
                     /locus_tag="VVO74_000732"
     CDS             33464..34288
                     /locus_tag="VVO74_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU5694779.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            34307..35293
                     /locus_tag="VVO74_000733"
     CDS             34307..35293
                     /locus_tag="VVO74_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU5694780.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            35344..35967
                     /locus_tag="VVO74_000734"
     CDS             35344..35967
                     /locus_tag="VVO74_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU5694781.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            36098..37555
                     /locus_tag="VVO74_000735"
     CDS             36098..37555
                     /locus_tag="VVO74_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU5694782.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            37578..37859
                     /locus_tag="VVO74_000736"
     CDS             37578..37859
                     /locus_tag="VVO74_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU5694783.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            37936..38421
                     /locus_tag="VVO74_000737"
     CDS             37936..38421
                     /locus_tag="VVO74_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU5694784.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            38438..39103
                     /locus_tag="VVO74_000738"
     CDS             38438..39103
                     /locus_tag="VVO74_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU5694785.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDIFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            39107..39970
                     /locus_tag="VVO74_000739"
     CDS             39107..39970
                     /locus_tag="VVO74_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEU5694786.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            39972..40676
                     /locus_tag="VVO74_000740"
     CDS             39972..40676
                     /locus_tag="VVO74_000740"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU5694787.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            40855..42528
                     /locus_tag="VVO74_000741"
     CDS             40855..42528
                     /locus_tag="VVO74_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU5694788.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            42640..43731
                     /gene="ulaG"
                     /locus_tag="VVO74_000742"
     CDS             42640..43731
                     /gene="ulaG"
                     /locus_tag="VVO74_000742"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU5694789.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            43845..45821
                     /gene="tkt"
                     /locus_tag="VVO74_000743"
     CDS             43845..45821
                     /gene="tkt"
                     /locus_tag="VVO74_000743"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU5694790.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGINTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            45938..46237
                     /gene="yajC"
                     /locus_tag="VVO74_000744"
     CDS             45938..46237
                     /gene="yajC"
                     /locus_tag="VVO74_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU5694791.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            46284..46712
                     /locus_tag="VVO74_000745"
     CDS             46284..46712
                     /locus_tag="VVO74_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU5694792.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            46714..47124
                     /locus_tag="VVO74_000746"
     CDS             46714..47124
                     /locus_tag="VVO74_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694793.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            47424..50075
                     /gene="adhE"
                     /locus_tag="VVO74_000747"
                     /gene_synonym="adhC"
     CDS             47424..50075
                     /gene="adhE"
                     /locus_tag="VVO74_000747"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU5694794.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSVHA
                     ARIVRDAAIAAGAPENCVQWITEPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFRPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        15396 a         8840 c        10616 g        15572 t
ORIGIN      
        1 ttagtccatt actaggggat tggaatatta tctgttcact aagaggacac gggcttgttc
       61 ccgtataaaa ctattttgga ggattaccca agtccggctg aagggaacgg tcttgaaaac
      121 cgtcaggcgt gtaaaagcgt gcgtgggttc gaatcccaca tcctcctttt atattaacgc
      181 gggatggagc agctaggtag ctcgtcgggc tcataacccg aaggtcgtag gttcaaatcc
      241 tgctcccgca ataaggctcg gtagctcagt tggtagagca atggattgaa gctccatgtg
      301 tcggcggttc gattccgtct cgcgccattt atatattttg gaagggtagc gaagaggcta
      361 aacgcggcgg actgtaaatc cgctccttcg ggttcggggg ttcgaatccc tccccttcca
      421 ttttacgggc atagtttaaa ggtagaacta aggtctccaa aaccttcagt gtgggttcaa
      481 ttcctactgc ccgtgttaat agaattatgg cgggtgtggt gaagtggtta acacaccaga
      541 ttgtggctct ggcatgcgtg ggttcgatcc ccatcactcg cctattttat attggggtat
      601 agccaagcgg taaggcaagg gactttgact ccctcatgcg ttggttcgaa tccagctacc
      661 ccagttacta tttgccggcg tggcggaatt ggcagacgcg ctggactcaa aatccagtgt
      721 ccgcaaggac gtgccggttc gaccccggcc gccggtatag tattaaagac aaggttttag
      781 gaccttgtct ttttgttatg tcataagaaa tttcttggaa ttgttactaa taattactaa
      841 tttcatataa aagcacatga ttaaaagtta tagaaagtga tatttttggg taattgtatc
      901 atagtaaaga acaggtattg ttttgctatt cgttacatct ccatcaatta agtaatgact
      961 tttactatca tagtaaatct tacctaggta tcttctatct ttagctactt cccaagaagc
     1021 aatatggccc gaaataatag ctttatgaaa tctaccagtg gtaattggaa atttgtttgt
     1081 aaatatcttt gaactcgtta gttctttcca aagcattcct gcttcttcat caatgcctgc
     1141 atgaacaaaa atttgggtat cagtttcata atagcgttta tccctatatc gctttttaaa
     1201 ccagtttata aatgggttga atttgatatt atttttaatt tcatttctaa cacctgtttc
     1261 aaagttgtta gcattcgatt taaaaatata gttcaattcc tctggagaga agaagctttt
     1321 tattgtttct ggaaatgctg aagcagtagg tttatctaaa atcaaccaat cataaaacca
     1381 ttcttcatga ttccctagaa gagtaataat ttgattagga taaacctcct caagttcgat
     1441 tattttggaa atgacttgaa aagattgaag tccattatca agataatctc ctagtaaaaa
     1501 taggcgatta tctttatcgt ttaaatttac tttattgaga gcgtctctga attcatccaa
     1561 gtatccatgt atatcagata ttgcgtataa tttagccata gcgtctcatc atttcttcat
     1621 gtgaggtagc ttttttgcca cattcaaccc attttttata agcttcatca gcgaccttaa
     1681 tatcatacat atcttcaatt ttctctataa cagcttgtct aataaagtca gtctttgttg
     1741 tattattttc ttcaacaata gcatttaata aagaatttaa ctcttgacta agttgaatag
     1801 aaatttgtgt agtaacaaca ttattcatat aacagccacc taatagttat tttagataca
     1861 ttatactcct agtctaaaag tttctcaata aaaaatttca ctttttatag ttatttattt
     1921 taataaaatt gtagtatctg caaggatgtg ccagttcgag accgaccgcc agtatagtaa
     1981 taaagacaaa gtttataagc cttgtctttt gttttctctt tataaaattt tatagtttag
     2041 ttactaactt tttttctttg ctcttaaaaa tctaatagca gaactgtatt tcttatttct
     2101 ctctaagtct ttttcagtaa ttaatggtag tcttgttaaa tctgaattat gccgtaaatc
     2161 cgccaacttt acaactctag cgagttcatt tttctttact agattgagat aagattgata
     2221 atcttgtcct tttttctttg tgagtatatc gacggcttct ataatgtttt ttgaaaaacc
     2281 ttcctttttt aggtctagta gggttagtga agtatcttca attacatcat gtagataggc
     2341 gacagctttc tcttcatcag ttgcgacaaa actagctact gtttcagggt gtttaatgta
     2401 gtcaattcct gctctatcaa tttgtccaaa gtgtgctttt ttagctactt catgtgcttt
     2461 tattacttgt gatgtatcca tgatttaatt ataaactttc catttataaa actcaattac
     2521 tttatagtaa atcatctagt ttatcagcta aatccttttg cttacttggg tacaagtgag
     2581 agtaggtatc aatcgtggtt gttatagaag catgtcctag tcgctctttt acaactagat
     2641 aatcttcccc ttggttaatc agcagggaag cgtgtgagtg cctaaaatcg tgtatgcgta
     2701 tcttttttag tgtgctatca cgttcaatga ttttcttgta ctgcttttca atagcatttt
     2761 ttgtaattgt gataggacta ttttgaaaca cttgtaatgt taggctattg ttggtaaatt
     2821 gctctaatag atgtttttgt cgctttttcc aatcttgtaa ttcttggctt aattttttat
     2881 tgataacaat tcttcttgtt tctgctttag tttttgttgt gctgatatga gttactcctt
     2941 tattaacata gacagacttc gtgatatgaa ttgtattact tgaaaagtcg atgtcttgcc
     3001 atgttagggc aagagcttcc ccaagtctta atcctgtaaa gaatagaaca gtaaagagta
     3061 gtttgatatt gtattcttcg ggttcaaata gtgtcaaaaa cttctgaaat tctttgactg
     3121 tccaaaattg catttttgtt ttttcaattg gcaacttttt tattaatttt gctggattgg
     3181 aggagtaata gccttttcgc aaaccaacat caaaaatttt tttgagtaaa atcatgattt
     3241 tgttaatagt atttgtgctt aacggtttat cagaattttt agctactttt tgcctaagat
     3301 gttctctaaa ttggtagatg tcttcatagg ttagttttcc gacattatcg accatagaaa
     3361 aataatcttt gatgtgtttg ttgtaattat tatcttgtgt attgatatag cttgcttttc
     3421 gatgatttat actatcttcc tccttaagta gttcatatag tatggggata gttattttag
     3481 ctccataaaa gcgttctttt aactctacac ttcgtaagta gtgttctgct tcaatagctt
     3541 cttttttcgt cttatagccc tttctgacaa gtctacgttg ctttagtgtt attgggtcaa
     3601 aaccgttgct aatatcaact acccaattac cgtctttacc ttttctaatt gccatatttt
     3661 actccttgag ggtactgttt tgaacatcaa aaacgagtaa ttcggtagca atagtagcag
     3721 gtatagtacc aattcgcttg ttctgataga ctgtaaagcc tcgggttatc agtagctctt
     3781 tcccttggcg gataatacgt ttagatgttc cctcaaagaa accgagggca attaggtcat
     3841 tcttagtaac agttgctatc atgtgactta ctcctttatt catctagtct tattttcttg
     3901 tactttacat gattatcgaa atactgaccg tatttataga ccttactagt gtattccgtt
     3961 tcatatagca cgactgaact atcatagtta aaatcttcat aagtgtaaaa tttatcttca
     4021 tcaggctttt tcaagttgcg tgatgaaaaa taggcttgct ttccgaagtt ttccaacaat
     4081 tcttgtccaa tacctttttc aaaatacttt gtgacatatc gaccgcgatt ttctttgctg
     4141 tcgacgtcaa ctttatttat ccatactgca ccatgccccc aaagttctaa taattgctta
     4201 tgtggaatat agggaacact gaatagcaaa atatgactat gccatgcttt acgtttttgc
     4261 ctctctaata ctgctatata ttttaattta cttttcttgg tattaaaaat gtggtagtta
     4321 aagcgtttaa taaatgtttt gagtgagtct ttgaagtggt ttctatcgct gatattttcc
     4381 ttagtggtca gtgtaagaaa agaagttgta tcatcaaaat tacaatcaac tagacggagt
     4441 aagttccact tggcttctaa gcgagtcttc ttcatacgtt caagacgttg ttcttgttct
     4501 aggggtgtta gttcatcaaa tgttctgcgt tttgcttttt ccttgttttc agtattagta
     4561 tctaaaatag attttccttt tgaaaatatt ggcttttcat attcccaaat ttcaatatag
     4621 gaagaagtgc ggactatttt tttattatat gaggtcataa aaaatagttc cttttaggtt
     4681 ggctttcgcc aaaagattgt ctatataata aataaactag gaggagcaaa gctcctccac
     4741 acttctatca tgtgtttcta agcatcgctc cgctaaacac gcttccagct tgctgacctc
     4801 cagtcagcag tttcgcttag tcacatgatg agaagtagta gttaaatttg tggtttagat
     4861 aattgtttta atgtttcgtc tgtagcccag ttggttgaaa tgatttcaag atggccttgg
     4921 tcatagacta gcaaatctcc gttaccaata aattgatatt tattatcttt gtcaatatat
     4981 aatgaaaaag tatctatacc aataacattt ttagaaatat caatagattc tttaggggta
     5041 tgtccaacaa tttgtttagg aaagtcttgg ttgggaagca attctaattc tctaaaatgt
     5101 gcccataaag gagaaccccc aagagctttc ccaccacgca ttggtcctat tgtataagct
     5161 aggatatcta attcttcttc atactctttg gtataaaggt taaaatgcca ttcttttggg
     5221 tcaaatatca gattgaaacc agcgtgactg actaaataat catctagttg ataagctatt
     5281 tgtaatttca aatcctgcaa caattctttt actgcgaaaa acacttctaa attttgaatt
     5341 gagaaaggag cttgttctcc cagtaaataa taagcatcat gattacctat aagattaatt
     5401 acatctattc cgttttgctc tttatctatt ttccaagagt ataaaaaagt gaggtctttg
     5461 gcataaagtt ggatattgtt agtttgacca tgtaaatcaa cataatcacc aagaaaaatg
     5521 attctcttaa tgttatgtgt ttggataatt ttgtcaacaa tgggtaaaat tagttgagat
     5581 tttaaatgta agtcaccaat taataatgtc ttcatatata ttcccctctt tatttttgat
     5641 attagtctaa gaatagaatt aagctctatc aaatttttta ggcaatagag aagtgttttt
     5701 tgaatattga taggattttt taactgtatc atagcagata acaggtattg ttttgctatt
     5761 ttttacatct ccatcaataa agtaatgact tttactatca tggtaaatct tacctaggta
     5821 acttttatct ttagctactt cccaagaagc aaaatgccca gagataatat ctttataaaa
     5881 tctaccagtt gtaataggaa atttgttggt aaatatctct ggactcgtta ggtctttcca
     5941 aagattatta gcttcttcat caatgccagc atggacaaaa atttgatttt ctgtttcaaa
     6001 ataacgacta tcttcatatc gtttttggaa ccagtttata aatggaatat acttatcatt
     6061 atttctaatt tcgtttctaa cacctgtttc aaagttgtta ggatttgttt ttaaaatata
     6121 gttcaattcc tctgtagaga agaaactctt tattgtttct ggaaacgcag aagcagtagg
     6181 attatctaaa atcaaccaat cataaaacca ttcttcatga tttccaaaaa gtgtaataat
     6241 ttgttttgga taaatctttt caagttcaat tattttagaa atgacttgaa aagattgaga
     6301 accgtaatca atatagtctc caagtaagat aagtttactt tgtttatcag ataaatctat
     6361 tttattgaga gatttaataa actcattgta gtgcccatgt atatcagata cggaataata
     6421 aattgccata taagattctt tctataatca acgtgaattt acagcgtata tgtaatttat
     6481 ataattagca aaatcaccca tacgttttct atcgttatga aacttatcga accaagaggt
     6541 atctttgtta ttgatttgag ccaagcctct aatagatata aggttatctc taattctatt
     6601 atgaatatta gttcttgtat catcaagtgt atcttgctct tcttttgtaa gtattcgcca
     6661 ttttcctctc atttcagcat acttcgcact gtactcgata agttctttcc agtatgcttg
     6721 aaattcaggg tcataaatgt ttgatgattt tataagttca tctaaaatta tttcagcttg
     6781 ttcaaaagtt acgatttctt tgtcttttag aaaatcgtta taagtaaaaa tttgcatagt
     6841 aagctccttt aatttttgaa ataattataa cacattattt agtaattaga attacattag
     6901 aacaagaaaa ccataaattt ccattgtatt gacctacgtt taaatctttt agagtaacag
     6961 gacaggtttt attatttgcc atttcttgaa cagaagcagt aggggataat gtatttactt
     7021 tgacttgtat catctccata aagaaatcag aatcctcatc ttgaattgac acgttaagtc
     7081 gtaaagctac gggcttatta gtctctctgt ctaatacttc tgtatagcct tttactgcta
     7141 taaatttgtt gccaagcagt tctggcttta aaaaatcatt tagcttcatg tgtacctctt
     7201 ttctatcatc gcagagcgat gaggaacaga tatttttgct gaaaatctat taaatttaag
     7261 caaaaatatc tgttgaaatt attttgactt tgttacgtat aattgtagtt cttttataaa
     7321 atcgaattga gttgtatcaa gataagggct ttcccagtat tgggcagatt ctttaccaga
     7381 gccttgtata taaagatagc ctgaaccttt ttcttcaata ggttttaact tatcaggagt
     7441 agccgaacca aagaccatgt gatagccttc actagaatta gcaccaagag caattctcaa
     7501 tcctaaatta tctctgagtt cagtacttaa agtagtacta gcatttactt gttgggcaga
     7561 cactaggata aaaatgcctg actgtcttcc aagtagaatg atttgtttaa tcccatccat
     7621 aacttcagtg ataatctctc ttgatttttt atctgaacct gtagcttgaa atgctcccat
     7681 ttcatcaaat ataagccata ctggcttaaa tccatggtta gtaaaatttg aaccatactg
     7741 aaagttatca cgcatgactt gatatcgttc ctgcatttcc tcaactacga ctctcacaat
     7801 gcgagctata ttatttgggg tggttgctac gtatttattt ccaaagtaat gagacaagct
     7861 acctaggtca gagttcttag ggtcagctat ataaactgtt gattgacgtt ttagaaattc
     7921 taaaatcaaa acagatataa gcacggattt cccacttcca gttccacccg atactaaaat
     7981 atgtgagcat ttgacaggat tataatttac accatatcct aaatctatat caaggctatc
     8041 tatctcttgt ctttggctgt gagattgtag aactaacctt tttggtttta tgtaatagaa
     8101 atgatattct ataaaactag gtcgaataat cttttcctca agctctagtt caagcacgtc
     8161 agaaagtaca tcatcaagag attgaacttt tttactaaat tcatcgcccg ttataagagc
     8221 tttgataaga acatgacctt tttgtctatc tatctcgtat tctaatactg cacttctaac
     8281 gattttttca tagcctgaac catctttaga tgtggtataa agtctgtttg tgtggagtac
     8341 ataaagtaag ctctcacgta taataaggta atgctctaag tcatatcgaa aaatttttat
     8401 tttcagatga attttataga taataaatcc acctaaaaat atgaagagaa tttgaacaaa
     8461 agttggagcc ctaatattaa caatagtgga aaatagaatg caggcagaga tacttagtat
     8521 cagccagtgc attattttta acttataaca ggaaattata ttgtttcttg ttaaatcagc
     8581 actttgtctt aatttaaaca tattagttag atacctttta ttttatctaa aagctctttt
     8641 aaaagttcgt aaaaccctaa gagcttgatt tttgcgaaat aatatgttga gataagtagt
     8701 ggaatacacc caaggataag gatagaattc gaaaagaaat gtccttgagg gaatataaaa
     8761 attgctatgc cagctaatat cacaaatcct aaaagaaata gatatgcttt taaattatca
     8821 ctcatttcat tacctcctct aataagcaat tattttaagg aaaactataa agatatagtc
     8881 gccgataaaa tagcgtggtc ggggaaaccg actttatttt gataatcagg attttctaag
     8941 aatctccaag aataacacac attagaaata ggaatgtttc ctataatatg gtctaattta
     9001 caatatttcc aagagttctc ctcagacgga gtatgtacag ttaaacctgc tttattcatt
     9061 tctgatttta gtaatggata ggagtaaaat tctctaggtt taccttgata ggaatgagta
     9121 tcatcattct gcttgaaaaa gccattatta aagtcaccta gaataattgt gttttcatga
     9181 attggtaaat tgaagattag cttgtctagt tgtgtttttc tgtgtttgaa atcttcaaaa
     9241 acattttccc ctcctatctt gatacgaact ccaataatgt ttaattcttg tccttcaatt
     9301 gtcactctaa cgtgtaaaaa gtttggatta ttatcatcat tatcgatagt aatgacttgg
     9361 caatcattaa ctaaatcact ctttattgca ataagaattt catttccaaa atctatagta
     9421 cgcacatctt caaagattgt ataaccatta gtttgaaggc tagaacagaa ttgagaatga
     9481 ttatctgttt ttacatactc tgtcagacag ataatatctg aattttgctg agctagttcc
     9541 tgcgcaatca tttcaggaat ttgttttcct tttcttgaac gtagatttat attccaagtg
     9601 gatgctgtaa gttgtatcat aaaatttcct cctaaaagtt agtccgcagg aggaggcacc
     9661 tcctcctgct atccttcgaa tccatcaaag atttctccta gttcgtcttc atcatagtag
     9721 ctttccaatt cctcatagaa gtaatctaag gcttcttggt caaaaaagtt cattgctatt
     9781 cctcctttca gtattttttt gtacatttta attgtacaaa attaaaagaa gaaagtcaac
     9841 aaaaaagtat actttaattt ccaaaatgta caaatttaat aaaaaaaaga atgagtctgg
     9901 gacaaaaaga ttttgatttt aggaattctt tattataaat tttaaaaatc gatagattat
     9961 acaaaaaagc gaacaagaca gaattctgag tatcagataa ctcgttttgt tcgcttttta
    10021 tatttaagat tagacttttg ttccagactc attttataaa attatttttg aaattccata
    10081 tggtatcaga aagtaatttg tggttgactg gtgcaacgat ttcaagaagc tgtttttcta
    10141 gaatagagaa tttcttgtca aaatcttttt caggttctga aatatcgtga tttaattggg
    10201 tcatcaattc tgctttaaga agaaatttaa cacatacacc taaagttaca ctttgagtat
    10261 ttgtggcact aggcaatatt tctttatatt ttttaattcc ttctgctact tcatcggaca
    10321 gtgcaacgtt caattttaat tccttttctt ccactggata aatatttttt aaagagatag
    10381 agttatcttg tacaactttt gtccagtttg ttacagtctt tgaattttga aacgcacgcg
    10441 ttaaaatggt agctttagtt atattgatac cttctgaagt ttcatatttc tcttttagca
    10501 ttcttaaata gtaagctgct tcaccagata ttcggacttg aaattgtgtc attattagta
    10561 cctccgtatt gtattatacc atttgtacat taaaaggaca atgtataaac gaataatcta
    10621 ccttctcgtt caagcatttt tacaagttta gtaatcttgt tgaagatgca ttccatgtgt
    10681 tacgtttaaa aaagggaatt aaagtaatct agttcctaaa aggttactaa aaataaaaaa
    10741 actatcgttt ttgtgataga ggtaactttt tgaaaaggct atttgactgg ctttatatac
    10801 ttatgaaatg ttaagagccc aactcaaaat ccagtgtccg caaggacgtg ccggttcgac
    10861 cccggccgcc ggtatagtat agtgttagga acgttgttat tcttcgttcc ttttttatat
    10921 tatttttggt ataattatag ttattcaaat tttatttaga ttaagaaagt gtaggggagt
    10981 atgtcttgtt ctatcgattt attaaaacat cggtatttga aaaatattaa agaaaatcct
    11041 gaattgtttg tcggaattga gttggagtat cctgttgcaa gtttagaagg ggatgctaca
    11101 gatgttgaag ttataaagga tctatttcat tatttagttt ctactttgga tctcaccgta
    11161 gcaaagatag atgattttgg caatctgatc cagttagtag atccgataag tcaggatgct
    11221 attttatttg aagtttccta tacaacgatt gagtttgcat ttggtaaggc tgaaacgatt
    11281 caagaggtcg aaaatcgttt caataattat atgaatgtaa ttcagagaaa gttagctgaa
    11341 tcaaatcatg ctattgttgg ctgtggtatc catcccaact gggataaaaa tgagaattgt
    11401 ccagtggctt atccacgcta tcagatgttg atggattatt tgaatttgag tagaaatatt
    11461 attaaatcag atttacatca tttccctgaa tatggtactt ttatctgtgg gagccaggtt
    11521 cagctggata tttcaaaaac caactactta cgggtgatta atgcttttac tcaaattgaa
    11581 gcggctaagg cttatttatt tgcaaactct gagttttcgg gtgcggattg ggatacgaaa
    11641 atttcaaggg atattttctg ggaagaatct atgcatggta tctatccaga gaatgttggg
    11701 gtcaatgcta gactccttaa tgatgaagct gatttttttg actatctaaa tcattctgcg
    11761 atttttactg cggaacgtga tgggcagacc tattattttt atcctattca ggctggggac
    11821 tatttggcta cgcctgaaat ccaagcattt tctctgaatg gggatgaggt tattatttac
    11881 ccccaagaga aggattttga aactcatcgt agttaccagt accaagactt aacgactcga
    11941 ggaacagttg agtttcgtag tgtgtgtaca cagccacttg atagaacttt tgcttctgca
    12001 gcttttcact tgggattatt ggttaattta gacaagttag aagcttactt agaaacagca
    12061 cctttcttta aagtatttgg ttatgattac aagtctttaa ggagacaatt ttctaagaaa
    12121 aatcttacag atgaggaaga aactacgatt attgaatttt ccaaagactt actcctacta
    12181 gctgaggagg gactagtggt gagaaataag gaagaaatga cctatttaca gcctttgaga
    12241 gaagaattga gcctataatt tctcttataa agggagaatt ttctgaaaaa tcatgatata
    12301 atggacgaga ctatagataa aggatagaga gtaatgacat tagtttatca atcaacgcgt
    12361 gatgccaaca atacagtaac tgccagtcaa gcaattttgc aaggtttggc gacggacggc
    12421 ggtttgttta caccggttac ttatccaaag gtagatttgg actttgacaa attgaaagat
    12481 gcttcttacc aggaagttgc taagctagtt ttgtcagcat ttttagatga ctttacagct
    12541 gaggagttgg actactgtat caacaatgcc tacgatagca aatttgatac tccagctatt
    12601 gcaccattag tgaaattaga tgggcaatac aatttggaac ttttccatgg ttcaacgatt
    12661 gcctttaagg atatggcctt gtctattttg ccatacttta tgacgactgc tgctaagaaa
    12721 catggtttgg agaacaagat tgttatcttg acagcgacat ctggtgacac ggggaaagct
    12781 gctatggcgg ggtttgcgga tgtgcctggt actgagatta tcgtctttta tccaaaggat
    12841 ggtgtcagca agattcaaga gttacaaatg accactcaga ctggcgacaa tactcatgtt
    12901 attgctattg atggtaactt tgacgatgcg caaacaaatg tgaagcacat gtttaacgat
    12961 gtggctcttc gtgaaaaatt gactaccaac aagttgcaat tttcatcagc taactctatg
    13021 aacattggtc gtctggtgcc acaaattgtt tattatgttt atgcttacgc tcaattggtt
    13081 aagactggtg aaactgtagc tggtgaaaag gttaacttca cagtaccaac aggaaacttt
    13141 ggaaatatct tggctgcctt ttatgccaaa caaattggtt tgccagttgg taaattgatc
    13201 tgtgcttcaa atgacaacaa tgttttgaca gacttcttta aaacacgtgt ctatgacaaa
    13261 aaacgtgagt ttaaggtaac aaccagccca tctatggata tcttggtatc ttcaaacttg
    13321 gagcgcttga ttttccatct tttgggaaat aatgctgaaa agacagctga actcatgaat
    13381 gctttgaaca tgcaaggaca atataagttg acagactttg atgcagagat tttggacctc
    13441 tttgcagctg aatatgcgac tgaggaagaa acagcggcag aaatcaagcg tgtttatgag
    13501 ttagattctt atattgagga tccacatacg gcggttgcct cagcagttta tagaaaatac
    13561 caagcggtta ctgatgatgc gactaagaca gtgattgctt caacagctag tccctacaag
    13621 ttcccagtag ttgcagtaga agctgtaact ggaaaagcag gtttaacaga ctttgaagct
    13681 ttggctcaat tacatgaaat ctcaggcgtt gcagtgccac cagcagttga tgggcttgag
    13741 acagctcctg ttcgtcacaa gacaacagtg gcagctgctg acatgcaagt agcggttgag
    13801 gcttatttag gactttaaga tagagggagt aaactcggtt gggaaaccaa ctgagtttct
    13861 tttcatcagg aggagagatt gtttaagaaa aataaagaca ttcttaatat tgcattgcca
    13921 gctatgggtg aaaacttttt gcagatgcta atgggaatgg tggacagtta tttggttgct
    13981 catttaggat tgatagctat ttcaggggtt tcggtagctg gtaatattat caccatttat
    14041 caggcgattt tcatcgctct gggagctgct atttccagtg ttatttcaaa aagcataggg
    14101 cagaaagacc agtcgaagtt ggcctatcat gtgactgagg cgttgaagat taccttacta
    14161 ttaagtttcc ttttaggatt tttgtccatc ttcgctggga aagagatgat aggacttttg
    14221 gggacggaga gggatgtagc tgagagtggt ggactgtatc tatctttggt aggcggatcg
    14281 attgttctct taggtttaat gactagtctg ggagccttga ttcgtgcaac gcataatcca
    14341 cgtctgcctc tctatgttag ttttttatcc aatgccttga atattctttt ttcaagtcta
    14401 gctatttttg ttctggatat ggggatagct ggtgttgctt gggggacaat tctgtctcgt
    14461 ttggttggtc ttgtgatttt gtggtcacaa ttaaaactgc cttatgggaa gccaactttt
    14521 ggtttagata aggaactgtt gaccttggct ttaccagcag ctggagagcg acttatgatg
    14581 agggctggag atgtagtgat cattgccttg gtcgtttctt ttgggacgga ggcagttgct
    14641 gggaatgcaa tcggagaagt cttgacccag tttaactata tgcctgcctt tggtgtcgct
    14701 acggcaacgg tcatgctgtt ggcccgagca gttggagagg atgattggaa aagagttgct
    14761 agtttgagta aacaaacctt ttggctttct ctgttcctca tgttgcccct gtcctttagt
    14821 atatatgtct tgggtgtacc attaactcat ctctatacga ctgattctct agcggtggag
    14881 gctagtgttc tagtgacact gttttcacta cttgggaccc ctatgacgac aggaacagtc
    14941 atctatacgg cagtctggca gggattagga aatgcacgcc tcccttttta tgcgacaagt
    15001 ataggcatgt ggtgtatccg cattgggaca ggatatctga tggggattgt gcttggttgg
    15061 ggcttgcctg gtatttgggc agggtctctc ttggataatg gttttcgctg gttatttcta
    15121 cgctatcgtt accagcgcta tatgagcttg aaaggatagg aaatgcaaaa aacagctttt
    15181 atttgggatt tagacgggac tttattggac tcttacgaag cgattttatc agggattgag
    15241 gagacttttg ctcagttttc tattccttat gataaggaga aggtgagaga gtttatcttc
    15301 aagtattcgg tgcaaaattt gcttgtgcgg gtggcagaag atagaaatct ggatgttgag
    15361 gtgctaaatc aggtgcgtgc ccagagtctg gctgagaaga atgctcaggt agttttgatg
    15421 ccaggtgcgc gtgaggtgct agcttgggca gacgaatcag gaattcagca gtttatatat
    15481 actcataagg ggaacaacgc ttttaccatt ctcaaggact tgggggtgga atcctatttt
    15541 acagagattt taaccagtca gagtggcttt gtgcggaagc caagtccaga agcggctacc
    15601 tatctgctag ataagtatca gctggatcct gagaagacct attatatagg ggaccggact
    15661 ttagatgtgg aatttgccaa gaatagcggt attcaaagca tcaacttttt agaatcttct
    15721 tttgaaggca atcacaggat tcaagcacta gcagatattt cccgtatttt tgagactaag
    15781 tgataaaaag attgtgtcag ttttgtgaca gagacctaac aaactatttc aagtaatcta
    15841 gtttgttaca aggaatagac agttctgtta aataggcccg agagggcttt ttttctacat
    15901 tttttgtgtt atgatagaca ggtactcatt tgaaaggaat ttgaaagaat gaagaaaaga
    15961 atgttattag cgtcaacagt agccttgtca tttgccccag tattggcaac tcaagcagaa
    16021 gaagttcttt ggactgcacg tagtgttgag caaatccaaa acgatttgac taaaacggac
    16081 aacaaaacaa gttataccgt acagtatggt gatactttga gcaccattgc agaagccttg
    16141 ggtgtagatg tcacagtgct tgcgaatctg aacaaaatca ctaatatgga cttgattttc
    16201 ccagaaactg ttttgacaac gactgtcaat gaagcagaag aagtaacaga agttgaaatc
    16261 caaacacctc aagcagactc tagtgaagaa gtgacaactg cgacagcaga tttgacaacc
    16321 aatcaagtga ccgttgatga tcaaactgtt caagttgcag atctttctca accaattgca
    16381 gaagctccaa aagaagtagc atcaaattca gaagttgcag agacagtgac tgctgcagaa
    16441 gaagtggcac catctacggg cacttctgtc ccagaggagc aaacggccga aacaactcgc
    16501 ccagttgaag aagtagctcc tcaggcaacg actctagctg agaagcagga aacacaagtg
    16561 agctctcaaa ccgagtcagc agtggaagca actacaatgc cagtagaaga aaaagcaacc
    16621 gaaacaactg caacaagttc agaagcaaaa gaagtagcat catcaaatgg agctacagca
    16681 gcagtttcta cttatcaacc agaagagacg aaaacaattt caacaactta cgaggctcca
    16741 gctgcgcccg attatgctgg actggcagta gcgaaatctg aaaatgcagg tcttcaacca
    16801 caaacagctg cctttaaaga agaaattgct aacttgtttg gcattacatc ctttagtggt
    16861 tatcgtccag gagacagtgg agatcacgga aaaggtttgg ctatcgactt tatggtacca
    16921 gaaagttcag aattagggga taagattgcg gaatatgcta ttcaaaacat ggccagccgt
    16981 ggcattagtt acatcatctg gaaacaacgt ttctatgctc cattcgatag caaatatggg
    17041 ccagctaaca cttggaaccc aatgccagac cgtggtagtg tgacagaaaa tcactatgac
    17101 cacgttcacg tttcaatgaa tggataaacc cgacttggta acatcatttt gacgaatgag
    17161 atctagcttt cgtgatagga agcgattctc gttcgttttt tctttgtcat actcttcgaa
    17221 aatctcttca aacaacgtca gttttatctg aaacctcaaa gctgtgcttt gagcaacctg
    17281 cgactagctt cctagtttgc tttttgattt tcattgagta tcaatttgaa tggaaaatgg
    17341 aaagttatca tcttgtaatg agttaagcaa cattcttgca atctatttta tagtagattg
    17401 aaactagaat agtacacaac tgcttctaaa acattgttag aaatcgattt gactgtcctg
    17461 atcgatttgt cctgctctta tttcatttca ctatacttta tattataatt gactggtcaa
    17521 atattgataa atcaataaaa agagagggga agaaatgcta gagattcaag atttactgta
    17581 tcaactccgc ttgtctgagc aagtgagtac gcaattgttt gaaaaagctt gggattagtt
    17641 tgacacggta tcagatttta ctgtttttgc tggagcattc tctttgtaac caaatggcgg
    17701 ttcaggagcg tttgaaaatt gatcaggctg ctttgacacg gaatttcaag attttggaaa
    17761 cggaaggttt ggtggagcgt catcgtaatc ctgaaaatca gcgggaagta ttggtagagg
    17821 ctgcgaagta tgccaaggag cagttagtgg tgaatccccc tctgcaacat atcaaggtta
    17881 aggaagagat ggaaagtatc ttaacagagt ttgagagaac agaactcagc cgtttattaa
    17941 ataaattggt tttgggtatt gaaaatatag aaatttaagg agaaatagat gtcaattatt
    18001 acaattattt taacaacgat cgttgcttgg gagcattttt acatttttta tttagaaagt
    18061 attgccacgc aatcagatgc gactagtcgt gtatttaata tggaaaggga agaattggct
    18121 catccgtcag taagtttatt gttcaaaaat caagggattt ataaggctct gctaggagtc
    18181 tgtctcttgt atggcattta tttctcacag aatttagaaa ttgtgactat ttttgtctta
    18241 tttgtgattg gtgctgcgac ttacggctct ttaacagcgg ataaaaaaat tattttgaaa
    18301 caaggtggat cagctatttt ggccttgatt agtattttac tctttaaata cacttgaagg
    18361 tcgattctaa tctcgctaat cctttttaat ccagaataag ggaaatatgt tatacttgtt
    18421 tttaagaaaa aagtttcatt gaattggttt tgaggagtta gaaatgaaag tattagtgac
    18481 aggttttgag cccttttgag gccattaaag gtttaccagc tgaaatccat ggtgctgagg
    18541 tccgttggct agaggtgccg acagtttttc acaaatctgc tcaagtattg gaagaagaga
    18601 tgaatcgtta tcaacctgac tttgtccttt gtattgggca agctggtgga agaactagtt
    18661 tgacacctga acgagtggcc attaatcaag acgatgcacg tacttctgat aacgaagata
    18721 atcaaccgat tgaccgtccc attcgcccag atggtgcttc ggcctacttt agtagtttgc
    18781 cgattaaagc gatggttcaa gctataaaaa aagagggctt accggcctct gtttccaata
    18841 cggcagggac ttttgtctgc agccatttga tgtatcaggc tctctatttg gtagaaaaga
    18901 aatttccata tgttaaggca ggttttatgc atattcctta tatgatggaa caggtggtga
    18961 acagaccgac tactccagct atgagtttag tggatattcg gcgagggata gaagcagcaa
    19021 tcggcgctat gatagaacat ggagatcagg aactcaagtt ggtaggcgga gaaactcatt
    19081 gatagaaaaa agcttgaggg gaaaaacctt caagcttttg gacgttttcg agccaatact
    19141 gctcggtaaa acataatttt agtgcattgg atataaggta ggagtgaaaa actagcaatg
    19201 ccaaaggtaa tccaattgag gaagtaccaa ggaagaagct gtaaatctag gacaaagcgc
    19261 tggaacttgt agcccttcat aaaggaacgg ctagttttta ggattcgtct tggtgggacc
    19321 tgtcctaggt ctagactata acagagaaga aattccacct gtgaataggc ataatactgt
    19381 ggaatataga ggatatttcc tacaatgatc aagatgagac ttgcaagaaa gtagagtcca
    19441 aagaccatga ggaaacgctc ggtttcaact gatgagagat ctagatttgg aaactcagga
    19501 tgtagggtga cgaatttttt ggctaaaaag ctactataaa agaggaggta aatcccaagt
    19561 aaattaggga tactccataa aaagagatag aaacgtttga gaagtagggt caaaaaggtt
    19621 tgagaaaagc gctcctcatc aaagagagct aggctgtttt ttacagatgg ctccgtttta
    19681 gaatctttca tgagtgtcag tgttgcatag acggaactgg tcaaaagaat agtcccgata
    19741 aaggagacta gtagaggaaa gaggtaggtt tgaagtattt ggccaagtat gctgaaaaat
    19801 ggctgttcta aaacagtccc gtggatccga gataagggat taagaaaact agataagatg
    19861 accagcatac tgggaaggat atagaggaga aagagacggg gggtgtcagc ctgaaaatgt
    19921 tttgactcct gacgaattgt ttttaaatca atttttggat agttcattct cttattatac
    19981 catagttctt atacatagtt cgtgacagtt cctacttttt ttgataaaat catacagtgt
    20041 gtccttgggc acactgtatg aactgggact gtctttccca gcttcggagg taaaaaatgt
    20101 cagattcacc aatcaaatat cgtttgatta agaaagaaaa acacacagga gctcgtctag
    20161 gagaaatcat cactccccac ggtacctttc cgacacctat gtttatgcca gttgggacac
    20221 aagccactgt caaaactcag tcacctgaag aattgaagga gatgggttcg ggaattatcc
    20281 tatcaaacac ctatcatctc tggcttcgcc ctggagatga actcattgca cgcgctggtg
    20341 gtctccacaa gttcatgaat tgggaccagc ctatcttgac agatagtggt ggttttcagg
    20401 tttattcttt agcagatagc cgtaatatca cagaagaagg agtaaccttt aaaaatcatc
    20461 taaatggttc taagatgctc ctatccccag aaaaagccat ctctattcag aataatctgg
    20521 gttcagacat catgatgtcc tttgatgaat gtcctcagtt ttatcaacct tatgactacg
    20581 ttaagaaatc gatcgagcgt accagccgtt gggctgagcg tggtttgaag gctcaccgtc
    20641 gtccacatga ccaaggtttg tttggaattg tgcaaggtgc aggatttgaa gaccttcgcc
    20701 gccaatcagc tcatgatctt gtcagcatgg atttctcagg ctactctatc ggtggtttgg
    20761 cagtgggaga aacccatgaa gagatgaatg cggtcttgga ctttacaact caactgctgc
    20821 ctgaaaataa acctcgttat ctgatgggtg tgggagcgcc agatagcttg atcgatgggg
    20881 tcattcgtgg ggtggatatg tttgactgtg tcttaccgac tcgaattgct cgtaacggga
    20941 cttgtatgac cagtcaagga cgtttggttg tgaaaaatgc ccagtttgct gaggacttta
    21001 cgccactgga tcctgagtgt gattgctaca catgtaataa ctatacacgc gcttaccttc
    21061 gtcacctgct caaggctgat gaaacctttg gtatccgctt gactagctac cacaatcttt
    21121 acttcttgct taacctgatg aagcaagtgc gacaagccat catggatgac aatctcttgg
    21181 aattccgtaa gtattttgtg gaaaaatatg gctataataa gtcaggacgt aatttctaaa
    21241 atggaattga tataagctaa aaatcctaag ttttctctta ggatttttct tctttttttg
    21301 atagaataaa gtgtacaatg aaaggaagaa taaactcgta tgcgcattaa atggttttcc
    21361 ttggttagga ttacaggttt acttttggta ctcttgtatc acttctttca gacgatcttt
    21421 cctggaggat ttttcggggt agatgtcttt ttcacatttt caggtttcct gattacagct
    21481 ctactcattg aagaattttc taaaaaccat gagattgatt tgataggatt ttttagaaga
    21541 cgcttttatc ggattgtgcc acctgtggtt ttgatggtct tggtgaccat gccttttact
    21601 ttcttggttc gccaagacta tgttgctgga attggtggcc agattgcgag cgtcttaggc
    21661 tttatgacca acttctatga actcctaaca ggtgggagtt atgaatctca gttcattcct
    21721 catttgtttg ttcataattg gagtttggca gttgaggttc actactatat tctttgggga
    21781 ttggcagttt ggttcttatc caaacaagct aaatcaaatg gtcagttgaa ggggatggtc
    21841 tttctcttat ctgctgttgc cttcttgatc agtttcttct ccatgtttat tggtagtttt
    21901 ctagtgacct cttattcctc tgtttatttc tccagtttaa ctcatgtcta tccattcttt
    21961 ttgggaagta tgttagcaac tattgtaggc gttcgtcaga cgacttccct cgtcaagcag
    22021 ttggataaaa tctgggattt acgaaagact ttggtagttt ttggaggagg ctttggtttc
    22081 ctagttcttt tgactttctt tgtcaaattc acttatcttt ttgcctatct tatcggcttc
    22141 ttacttgcca gtcttgcagc tcttgccatg attctggcgg cgcgtgtctt acatgaaaag
    22201 acacatcata tacaggagcc gaagattatc agctttttag cggatactag ctatgcggtt
    22261 tatcttttcc attggccttt ctatatcatt ttctcacagt tgacatcaaa tcttcttgct
    22321 gtattactga ctctgatttg ttcttatggc tttgccagtc tgtcattcta tgtattggaa
    22381 ccttggattg caggcaagaa cacacctatt gtccaaaccc ttcgtcccct gccttatatt
    22441 cacgcaattc ttgcagcagg tacaggaatc ttgaccatca ttgtctgcac ggtgaccttg
    22501 ttggcaccac aagtgggagc gtttgagaca gacttgactg tcaatggctt gaagcaagct
    22561 gcaacaaata ttggccagac caaggtgatg gcagaacggg cagatgcaaa cagtttggga
    22621 attgctgatg gcactatgtt aattggtgac tcagtggctt taagggcaaa tacagcacta
    22681 cagacagctc ttcctggagc acagattaac gcgcaggtca gcgtaacaac caagaccgca
    22741 aatgaaatca tgctaaataa tagccagaat aaatttttac ctaagacggt ggtcattgcg
    22801 actggggtaa ataatcctga gaattacaag gatgactggg acagtatcgt gaaaaatctt
    22861 cctaagggac accatatgat tttggtgact ccttatgagg gagataagac aaaagagacc
    22921 tatgccatcg ttgagaaggc tgctgcctat atgagagaat tggcagagaa gacaccttac
    22981 attacgatag cagattggaa tcaagttgcg aaagagcatc cagaaatttg ggcaggaaca
    23041 gaccaggttc atttcgggag tgagagtagc actatcgaag caggagcaaa attgtatgca
    23101 gatacgattg ccacagcttt gcagacagct caagacaagc cggttaaatc aaaataactt
    23161 gtattaaaaa agagaagagt tggagaaatc cagctctttt aaaatatctc caaaaaatag
    23221 gtctatacca tttacaaata aaaaagaaag gtttataatg taattgacat aataaattgt
    23281 agaatcaatc ttttaaggag gttaacatta tgcctaacta tattaaagcg gatcagtttt
    23341 tctacccaca cggagttcgt cgaggtggtt acttggaact tgtggacggc aagtttggga
    23401 aacatgtaga gcagattcct gaaggggctg aggtgattga ctatacaggt tatagcattg
    23461 ccccaggtct tgtggatact catattcatg gatatgcagg tgtagatgtg atggacaaca
    23521 acattgaagg tacattgcat actatgagtg aaggacttct tagtaccggt gttaccagtt
    23581 tcttacccac aactttaaca gccacttatg agcaattgct tgcagtcact gaaaatcttg
    23641 gaaaccatta taaagaagca acaggtgcta agattcgtgg gatttattat gaaggtccat
    23701 atttcacaga aacttttaag ggggcacaaa atccaactta tatgagagac ccgggtgttg
    23761 aggagtttca ttcttggcaa aaagcggcaa atggcttgct taataaaatt gcccttgcac
    23821 cagaacgtga tggggtggag gactttgttc gtacagttac gggcgaaggt gtgacggttg
    23881 ctcttggaca ttcaaacgcg acttttgatg aagccaaaaa agcagtcgat gctggagcga
    23941 gtgtttgggt gcatgcctac aatggaatgc gtgggttgac tcaccgtgaa ttgggtatgg
    24001 ttggagccat gtaccaattg ccacatacct atgcagagtt gatctgtgat ggccaccacg
    24061 tagatccaaa ggcttgcgaa attcttatca aacaaaaagg aacagaaaac atcgctctta
    24121 tcacagactg tatgacagct gggggattgg aagacggaga ttatatgttg ggagaattcc
    24181 cagttgtcgt tgcaaatgga actgcacgcc tcaaatcgac aggtaacttg gcaggttcta
    24241 tcctcaaact caaagatggt ttgaagaatg tggtcgaatg gggaattgcg aatccgcatg
    24301 aagcagtcat gatggccagc ttcaacccag ctaaatccgt tcacatcgat gatgtctgtg
    24361 gccaaatccg tgaaggctac gacgctgact tcatcgtatt agataaagat ttggaattgg
    24421 tagcaaccta cctagatggc gtaaaacgtt atcaagcata agagagaaag cagaagttag
    24481 agactaactt ctgctttttt atgcagggta ctttactggt aaataaaaag ttaaaaaaat
    24541 cacaaaaaaa gcttgaagaa acaaagaaaa aggcttacaa ttgaactata aatattacaa
    24601 ataaaaaaac ggaggagtgc tttatgaaag cctatactta tgttaaacca ggacttgctt
    24661 cttttgttga tgtagacaaa ccagttattc gcaagccaac agatgctatt gtgcgtattg
    24721 taaaaaccac tatttgtgga acagacctcc atattatcaa aggggatgtt cctacttgcc
    24781 aaagtggtac cattcttggc cacgaaggga ttgggattgt tgaagaagtt ggggaaggag
    24841 tttccaactt caaaaaaggt gacaaggtct tgatttcttg cgtctgtgcc tgtggtaaat
    24901 gctactactg taaaaaagga atttatgctc actgtgaaga cgaagggggc tggattttcg
    24961 gtcacttgat tgatggtatg caggctgaat atctacgtgt ccctcatgca gataatactc
    25021 tttaccatac tccagaagac ttgtcagatg aagctttggt tatgctgtca gacattctgc
    25081 ctactggata tgaaattggt gtcttaaaag ggaaagtaga acctggttgc agcgtagcca
    25141 ttattggttc aggtccagtt ggattggctg ctcttttaac agcccaattc tattcaccag
    25201 ctaaattgat tatggtagac ctagacgata accgcttgga aactgcccta tcattcggtg
    25261 cgactcataa ggttaattct tcagaccctg aaaaagccat taaagaaatt tatgatttga
    25321 cagatggtcg tggtgtggat gtcgctatcg aagctgttgg tattcctgca acatttgatt
    25381 tctgtcaaaa gattatcggt gtagacggaa cggttgccaa ctgtggtgtg catggtaaac
    25441 cagttgaatt cgatttagat aaactttgga ttcgcaacat caatgtaaca actggtttgg
    25501 tatctacaaa tacgactcca caattgttga aagcacttga aagtcataag attgaaccag
    25561 aaaaattggt aactcactat ttcaaactca gtgaaattga aaaagcctat gaagtcttca
    25621 gtaaggcagc agaccaccat gccattaagg tcattatcga aaacgatatc tcagaagcct
    25681 aagtagtaaa aatatttttg tacataagta aatagaaatt cagtcatcca tcagatggct
    25741 ggatttttta tcaaaaaatt aagaaatgag catatttctt tccttgtctg gcggaattgg
    25801 ttataatata cggtacaaag gaatgaatga atatgtatcg tgttatagaa atgtacggag
    25861 attttgaacc gtggtggttc ttagaaggtt gggaagaaga tattgtagca agtagaaaat
    25921 ttgaccagta ttatgatgct ctcaaatact acaaaacttg ctggtttaga ttggaacaag
    25981 aatcccctct ttataaaagt agaagcgact tgatgaccat tttttgggac ccggaagacc
    26041 aacgctggtg tgatgaatgt gatgagtatt tacaacaata ccattctttg gctcttttgc
    26101 aggatgagca ggttatccca gacgaaaaac tacgctcagg ctatgaaaaa caaaccagtc
    26161 aggaaaggaa tcgttcttgc cgtatgaaat taaaatagag aaaagtaact tttttggagt
    26221 tgcttttttt atttttctaa cgctttgcga atagtatagg tgaggaggta agtatggttc
    26281 aagaaattgc acaagaaatc attcgttcag ctcggaaaaa agggacgcag gatatttatt
    26341 ttgtccctaa gttagacgcc tatgagcttc atatgagggt aggagacgag cgctgtaaaa
    26401 ttggtagcta tgattttgaa aagtttgcag ccgttatcag tcactttaag tttgtggcgg
    26461 gtatgaatgt gggagaaaaa agacgtagtc aactgggttc ctgtgattat gcctatgacc
    26521 agaagatggc gtctctacgt ttatctactg taggcgatta tcggggacat gagagtttgg
    26581 ttatccgttt gttgcacgat gaggagcagg acttgcattt ttggtttcag gatattgaag
    26641 aattaggcaa gcagtacagg caacggggac tctatctttt tgctggcccg gttgggagtg
    26701 gtaagacgac cttgatgcat gaattgtcca agtcactctt taaaggacag caagttatgt
    26761 ccatcgaaga tcctgtcgaa atcaagcagg acgacatgct tcagttgcag ttgaacgaag
    26821 caatcggcct aacctatgaa aatctaatca aactttcctt gcgtcatcga ccagatctct
    26881 tgattatcgg agaaattcgt gacatcgaga cggcgcgtgc agtggtcaga gctagtttga
    26941 caggtgcgac agtcttttca accattcacg ccaagagtat ccgaggtgtt tatgagcgtc
    27001 tgctggagtt gggtgtgagt gaagaagaat tggcagttgt tctgcaagga gtctgctacc
    27061 agagattaat cgggggagga ggaatcgttg actttgcaaa cagagattat caagaacacc
    27121 aagcagccaa gtggaatgag caaattgacc agcttcttaa agatggacat atcacaagtc
    27181 ttcaggctga gacggaaaaa attagctaca gctaagcaaa aaaatatcat caccctattt
    27241 aacaatctct tttctagcgg ttttcatctg gtggagacta tctccttttt agataggagt
    27301 tccttgttgg acaagcagtg tgtgacccag atgcgtacag gcttgtctca ggggaaatca
    27361 ttctcagaaa tgatggaaag tttgggatgt tcaagtacca ttgtcactca gttatctcta
    27421 gctgaagttc atggcaatct tcacctgagt ttgggaaaga tagaagaata tctagacaat
    27481 ctggccaagg tcaagaaaaa gttaattgaa gtagcgacct atcctttgat tttgctgggt
    27541 tttcttctct taattatgct ggggctacgg aattacctgc tcccacaact ggatagtagc
    27601 aatattgcca cccgaattat cggtaatctg ccacaaattt ttctaggcat ggtagggctt
    27661 gtttccgtgc ttgccctttt agcactaact ttttataaaa gaagttctaa gatgagtgtc
    27721 ttttctatct tagcacgcct tccctttatt ggaatctttg tgcagaccta cttgacagcc
    27781 tattatgcac gtgaatgggg gaatatgatt tcacagggaa tggagctgac gcagattttt
    27841 caaatgatgc aggaacaagg ttcccagctc tttaaagaaa tcggtcaaga tctggctcaa
    27901 accctgaaaa atggccgtga attttctcag acgataggaa cctatccttt ctttaggaag
    27961 gaattgagtc tcatcataga gtatggggaa gttaagtcca agctgggtag tgagttggaa
    28021 atctatgctg aaaaaacttg ggaagccttt tttacccgag tcaaccgtac catgaatttg
    28081 gtgcagccac tggtttttat ctttgtggca ctgattatcg ttttacttta tgcggcaatg
    28141 ctcatgccca tgtatcaaaa tatggaggta aatttttaaa atgaaaaaaa tgatgacatt
    28201 cttgaaaaaa gctaaggtta aagcttttac attgattgag atgttggtgg tcttgctgat
    28261 tatcagcgtg cttttcttgc tctttgtacc taatctgacc aagcaaaaag aagcagtcaa
    28321 tgacaaagga aaagcagctg ttgttaaggt ggtggaaagc caggcagaac tttatagctt
    28381 agaaaagaat gaagatgcta gcctaagaaa gttacaagca gatgggcgca tcacggaaga
    28441 acaggttaaa gcttataatg aatactatac taaaaatgga ggggcaaatc gtaaagtcaa
    28501 tgattaaggc ctttaccatg ctggaaagtc tcttggtttt gggacttgtg agtatccttg
    28561 ccttgggctt atccggctct gtccagtcca cttttgcagc agtagaggag cagattttct
    28621 ttatggagtt tgaagaactc tatcgggaaa cccaaaaacg cagtgtagcc agtcagcaaa
    28681 agactagtct aaatttagat gggcagacgc ttagcaatgg cagtcaaaag ttgacagttc
    28741 ctaaaggaat tcaggcacca tcaggccaaa gtattacatt tgaccgagct gggggcaatt
    28801 cgtccctggc taaggttgaa tttcagacca gtaaaggagc gattcgctat caattatatc
    28861 taggaaatgg aaaaattaaa cgcattaagg aaacaaaaaa ttagggcagt gattttactg
    28921 gaagcagtag tcgctctagc tatctttgcc agcattgcga ccctcctttt gggacaaatt
    28981 caaaaaaata ggcaagagga agcaaaaatc ttgcaaaagg aagaagtctt gagggtagct
    29041 aagatggcct tgcagacagg tcaaaatcag gtaaacataa acggagttga gattcaggtg
    29101 ttttctagcg aaaagggatt ggaggtctac catggttcag aacagttgtt ggcaatcaaa
    29161 gagccataag gtcaaggctt ttaccttgtt agaatccctg cttgccctga ttgtcatcag
    29221 tgggggctta ctcctttttc aagctatgag tcagctcctc atttcagaag ttcgctacca
    29281 gcaacaaagc gagcaaaagg agtggctctt gtttgtggac caacttgagg cagaattaga
    29341 ccgttcgcag ttcgaaaaag tagaaggcaa tcgcctatac atgaagcaag atggcaagga
    29401 catcgccatc ggtaagtcaa agtcagacga ttttcgtaaa accgatgcta gtggacgggg
    29461 gtatcagcct atggtttatg gcctcaaatc agctcagatt acagaggaca atcaactggt
    29521 tcattttcgt ttccagtttc aaaaaggctt agaaagggag ttcatctatc gtgtggaaaa
    29581 agaagaaagt taaggcaggt gttctcctct acgcagtcac catagcagcc atctttagtc
    29641 ttttgttgca attttatttg aaccgacaaa tcgcccacta tcaagactat gctttaaata
    29701 aagaaaaatt ggttgctttt gccatggcta aacgaaccaa ggataaagcc gagcaagaaa
    29761 gtggggaaca ggtttttaat ctaggtcagg taagctatca aaacaagaaa acaagcttgg
    29821 tgacgactgt tcgtacgtct aagagccaat atgagtttct gtttccttca gtcaaaatca
    29881 aagaagagaa aagagataaa aaggaagagg tagcgaccga ttcaagcgaa aaagcggaga
    29941 aaaaaaatca gaagagaagc ctgaaaagaa agagaattcc tagtcaattc aactataatg
    30001 cgttgaatcc agaatagtcc actgtagttt ctagaaaatt gctggaaatg gatgttaagc
    30061 tccaattcat ttgtttatat cttatttcag tttactatac tttgtgctaa attaaagata
    30121 tgaaacatga ttttaaccac aaagcagaaa ctttcgattc ccctaaaaat atcttcctcg
    30181 caaacttggt atgtcaagca gccgagaaac agattgatct tctatcagac aaagaaattt
    30241 tagatttcgg tggtgacacg ggtctattag ccttgcccct agcccctagc caagcaggct
    30301 aagtcagtca ctcttgtaga catttctgag aaaatgttgg agtaagctcg tttgaaagcg
    30361 gagcagcaag caatcaagaa tatccagttt ttggagcaag atttaccgaa aaatcccttg
    30421 gagaaagagt ttgattgcct tgctgttagt cggcttcttc atcatatgcc tgatttggat
    30481 gcggatctct cactgtttca tcaacatttg aaggaagata ggaaactcat cattgctgat
    30541 tttaccaaga cagaagctaa tcatcatgga tttgatttag ctgaactgga aaacaagcta
    30601 attgagcatg gtttttcatc tgtgcatagt cagattctct atagcgctga agacctgttt
    30661 caagggaatc actcagaatt ctttttaaca gtatcccaaa aatcactcgc ctagtcaggg
    30721 agtgattttt ctataaggat ggaaaaaaga agggaaattt gataagatag gaatatggat
    30781 tttgaaaaaa ttgaacaagc ttatatctat ttactagaga atgtccaagt catccaaagt
    30841 gatttggcga ccaactttta tgacgccttg gtggagcaaa atagcatcta tctggatggt
    30901 gaaactgagc taaaccaggt caaagacaac aatcaggccc ttaagcgttt agcactacgc
    30961 aaagaagaat ggctcaagac ctaccagttt ctcttgatga aggctgggca aacagaaccc
    31021 ttgcaggcca atcaccagtt tacgccagat gctattgcct tacttttggt atttattgtg
    31081 gaagagttgt ttacagagga ggaaattact atcctcgaaa tgggttctgg gatgggaatt
    31141 ctaggcgcta ctttcttgac ctcgcttgat aaaaaggtgg attacttggg aatggaagtg
    31201 gatgatttgc tgattgatct ggcagctagc atggcagatg taattggttt gcaggctggc
    31261 tttgtccaag gagatgccgt tcgcccacaa atgctcaaag aaagcgatgt ggtcatcagt
    31321 gacttgcctg tcggctatta tcctgatgat gccgttgcgt cgcgtcatca agttgcttct
    31381 agccaagaac atacttacgc ccatcacttg ctcatggaac aagggtttaa gtaccttaag
    31441 tcagatggat atgctatttt tctagctccg agtgatttgt tgaccagtcc tcaaagtgat
    31501 ttgttgaaag tctggttgaa agaggaggca agtctggttg ctatgattag tttacctgaa
    31561 aatctctttg ctaatgctaa acaatctaag actattttta tcctacagaa gaaaagtgaa
    31621 atagcagtgg agccttttgt ttatccactt gctagcttgc aagatgcaag tgttttaatg
    31681 aaatttaaag aaaattttca aaaatggact caaggtactg aaatataaaa tagattttgt
    31741 tataatagtt gaaaacgctt aaaaaggggt atcatgttat gacaaaaaca attgcaatca
    31801 atgcaggaag ttcaagtttg aaatggcaat tatacttaat gccagaggaa aaagtgttag
    31861 ccaaaggttt gattgaacgt atcggtttga aagattcaat ttcaactgta aaatttgacg
    31921 gccgttctga acaacaaatt ttggatattg aaaatcatac acaagccgtt aaaattttat
    31981 tggatgactt gattcgtttc gatattatca aggcttatga cgagattaca ggtgttggac
    32041 atcgtgttgt tgctggtgga gaatatttca aagaatcaac agttgttgag ggagatgttt
    32101 tagaaaaagt tgaagagttg agtttgttgg ctcctctaca caacccggcc aatgcagcag
    32161 gtgttcgtgc cttcaaggaa ttgttgccag acattaccag tgtagttgtt tttgatactt
    32221 ccttccacac aagtatgcca gagaaagctt atcgctaccc tctaccaaca aaatattaca
    32281 cagaaaacaa ggttcgtaaa tacggtgctc atggtacaag tcaccagttt gtagcaggag
    32341 aagctgcaaa actcttggga cgtccattag aagacttgaa gttaattacc tgtcatattg
    32401 gtaacggagg ctcaattaca gctgtgaaag ccggcaaatc tgtagacact tctatggggt
    32461 tcactcctct tggtggtatt atgatgggaa cgcgtacagg ggatattgat ccagctatca
    32521 ttccttattt aatgcaatat acagaggatt ttaacacacc agaagatatc agtcgtgttc
    32581 ttaaccgtga atcaggtctt ttgggagttt ctgctaattc tagcgatatg cgcgatatag
    32641 aagcagctgt agcagaaggg aatcacgagg ctagcttggc ttatgaaatg tatgttgacc
    32701 gtatccaaaa acatatcggt cagtaccttg cagtgctaaa tggagcagat gtcattgttt
    32761 tcacagcagg tgtcggtgaa aatgcagaga gtttccgtcg tgatgtaatc tcagggattt
    32821 cgtggtttgg ttgtgatgtt gatgatgaaa agaatgtctt tggcgttaca ggagacatct
    32881 caacagaggc agctaaaatc cgtgtcttgg ttattccaac agatgaagaa ttagtcattg
    32941 cccgtgacgt tgaacgcttg aaaaaataag tgaaactaaa aaaatattca atacaaggag
    33001 ttgggaaagt tatttttcca gcttcttttt ctgatgaaat tgtccaaaac cttgctatga
    33061 ttggcttttt tgaaaaatat ggtataatag tagtaattta atagatggag ttgagttttg
    33121 aagaaaaact ttcgtgtaaa aagagagaaa gattttaagg cgattttcaa ggaggggaca
    33181 agttttgcta atcgcaaatt tgtggtctac caattagaaa accagaaaaa ccattttcga
    33241 gtaggtctat cagttagcaa aaaactgggg aatgccgtca ctagaaatca aattaagcga
    33301 cggattcggc atattatcca gaatgcaaaa gggagtctgg tagaagatgt cgactttgtt
    33361 gtcattgctc gaaaaggagt cgaaaccttg ggatacgcag agatggagaa aaatctactc
    33421 catgtattaa aattatcaaa gatttaccgg gaaggaaatg ggagtgaaaa agaaactaaa
    33481 gttgactagt ttgctaggac tgtctctgtt aatcatgaca gcctgtgcga ctaatggggt
    33541 aactagcgat attacagccg aatcggctga tttttggagt aaattggttt acttctttgc
    33601 ggaaatcatt cgctttttat cgtttgatat tagtatcgga gtggggatta ttctctttac
    33661 ggtcttgatt cgtacagtcc tcttgccagt ctttcaggtg caaatggtgg cttctaggaa
    33721 aatgcaggaa gctcagccac gcattaaggc gcttcgagaa caatatccag gtcgagatat
    33781 ggaaagcaga accaaactag agcaggaaat gcgtaaagta tttaaagaaa tgggtgtcag
    33841 acagtcagac tctctttggc cgattttgat tcagatgccg gttattttgg ccctgttcca
    33901 agccctatca agagttgact ttttaaagac aggtcatttc ttatggatta accttggtag
    33961 tgtggataca acccttgttc ttccgatttt agcagcagta ttcacctttt taagtacttg
    34021 gttgtccaac aaagctttgt ctgagcgaaa tggcgctacg actgcgatga tgtatgggat
    34081 tccagtcttg atttttatct ttgcagttta tgcgccaggt ggagtcgccc tatactggac
    34141 agtgtctaat gcttatcaag tcttgcaaac ctatttcttg aataatccat tcaagattat
    34201 cgcagagcgc gaggccgtag tacaggcaca aaaagatttg gaaaatagaa aaagaaaagc
    34261 caagaaaaag gctcagaaaa cgaaataaat aaggaggaat ctggtaatgg tagtatttac
    34321 aggttcaact gttgaagaag caatccagaa aggattgaaa gaattagata ttccaagaat
    34381 gaaggctcat atcaaagtca tttctaggga gaaaaaaggc tttcttggtc tatttggtaa
    34441 aaaaccagcc caagtggata ttgaagcgat tagtgaaacg actgttgtca aagcaaatca
    34501 acaggtagta aaaggcgttc cgaaaaaaat caatgatttg aacgagcctg tgaagacggt
    34561 tagtgaagaa accgttgacc ttggtcatgt agttgatgct attaaaaaaa tagaggaaga
    34621 aggtcaaggt atttctgatg aagtcaaggc tgaaatctta aaacatgaaa gacatgccag
    34681 cactatctta gaagaaactg gtcacattga gattttaaat gaacttcaaa tcgaggaagc
    34741 gatgagggaa gaagcaggcg ctgatgacct tgaaactgag caagaccaag ctgaaagtca
    34801 agaactagaa gacttgggct tgaaagttga aacgaacttt gatattgaac aagtagctac
    34861 ggaagtaatg gcttatgttc aaacgattat tgatgacatg gatgttgagg ctacactttc
    34921 aaatgattat aaccgtcgta gcatcaattt gcaaattgat actaacgaac caggtcgtat
    34981 tatcggctac catggtaaag tcttgaaggc cttgcaactg ttggctcaaa attatcttta
    35041 caactgctat tcaagaacct tctatatcac tattaatgtc aatgattatg ttgaacaccg
    35101 tgcagaagtc ttgcagacct atgcgcaaaa attggcgatt cgtgttttag aagaaggacg
    35161 tagtcatcaa acagatccaa tgtcgaatag tgaacgcaag attatccacc gtattatttc
    35221 acgtatggat ggcgtgacca gttactctga aggtgatgag ccaaatcgct atgtcgttgt
    35281 agatacagaa taagtaaaat cagggttgac ctgatttttt gctagctaga ggaggttaaa
    35341 ctgatgttga ataagataag agactattta gactttgctg gtttgcagta ccgtaatcct
    35401 gataaagcgg gagcagagcg agagaagatg ctggcattcc gccacaaagg acaagaggcc
    35461 cgaaaggctt ttacagaact ggccaaagcc tttcaagcaa gccatccaga atggcaactc
    35521 caacagacta gtcagtggat gaatcaggcc cagcgtttga gaccacattt ttgggtttat
    35581 ctacagagag acggacaagt gacagaacct atgatggcct tacgtttgta tgggacatct
    35641 actgactttg gaatttcttt ggaagtcagt ttcatcgaac gtaagaagga tgagcaaaca
    35701 ctgggcaagc aggccaaagt tttagacatt ccaaccgtta aagggattta ttatctaacc
    35761 tactctaatg gtcaaagtca acggtgggag gcgaatgaag aaaagcgtcg tactttacgc
    35821 gagaaggtga gaagtcaaga agttcgaaaa gttttagtga aggtagatgt tcctatgaca
    35881 gaaaattcgt ctgaagaaga aatcgtagaa ggcttattga agtcttattc taaaattctt
    35941 ccctattatc tagctacgag aaaataagat aatttgtaaa acatcataaa tcatacagtc
    36001 caagagtgaa cagtccgctg tgtaattctt ggtctttttg tttgcgcttt cgcattatat
    36061 aataaactta caaaaacaat tcaaaaggag aacaattatg gaagtcgttt caagtgttct
    36121 aaattggttt tctagcaata ttttgcagaa tcccgcattt ttcgtaggtt tattggtgtt
    36181 gataggatat gcacttttga aaaaacctgc ccatgacgtt ttttcagggt ttgttaaagc
    36241 aacagtaggg tatatgttgc ttaacgtggg tgctggtggt ttggttacaa cctttcgtcc
    36301 aatcttagca gctcttaact acaaattcca aattggtgca gcggttatcg acccttactt
    36361 tggacttgct gcagcaaaca acaaaattgc agcagagttt ccagattttg ttggaactgc
    36421 aactacagct ctattgattg gttttggaat aaatatcttg ctcgtagctc ttcgaaagat
    36481 tacgaaggta agaaccctct ttattactgg tcacatcatg gtacaacaag ctgcaacagt
    36541 atctcttatg gttctattct tagtaccaca attgcgcaat gcttacggta cagcagcgat
    36601 tggtatcatc tgtggacttt actgggcagt tagttcaaat atgactgttg aggcaactca
    36661 acgcttgact ggtggtggcg gatttgcgat tggtcaccaa cagcaatttg caatctggtt
    36721 tgtagataaa gtagcaggac gctttggtaa gaaagaagaa agtttagaca atcttaaatt
    36781 acctaagttc ctctcaatct tccacgatac agttgttgca tctgctacct tgatgctcgt
    36841 attcttcgga gccattcttt taatcttggg tccagacatt atgtctaata aagaagtcat
    36901 cacttcagga actctattca atcctgctaa acaagatttc tttatgtaca ttatccaaac
    36961 agcctttacc ttctcagttt acttgttcgt tttgatgcaa ggtgtccgaa tgttcgtatc
    37021 tgagttgaca aacgccttcc aaggtatttc aaacaaattg ttgccaggtt cattcccagc
    37081 ggttgacgtt gcagcttctt atggatttgg ttctccaaat gctgtcttgt caggatttac
    37141 ctttggtttg attggtcaat tgattacaat tgtcttgctc atcgtcttta aaaatccgat
    37201 tcttattatt acaggatttg taccagtgtt ctttgacaat gcagccattg cggtctacgc
    37261 tgataaacgc ggcggatgga aagcggctgt tatcctttcc tttatatcag gtgtccttca
    37321 agttgctcta ggagctcttt gtgtggccct tctcgatttg gcatcttatg gtggctacca
    37381 tggaaatatc gactttgaat tcccatggct tggatttgga tatatcttca aataccttgg
    37441 tattgttggt tatgtacttg tgtgtctctt cttgcttgtt attcctcaac ttcaatttgc
    37501 caaagcaaaa gataaagaga aatattacaa cggtgaagtt caagaagaag cttagtatct
    37561 agaaaaggag aaataaaatg gttaaagtat tagcagcgtg cggaaatgga atgggttcat
    37621 caatggttat caagatgaag gttgaaaatg ctctccgtaa gcttaatcaa acagatttta
    37681 cagtcaattc atgcagtgtc ggtgaagcta aaggtttagc agtaggatat gacatcgtaa
    37741 tcgcttctct tcatttgatt caagaattgg aagggcgaac taatgggaag ttaattgggc
    37801 ttgataactt gatggatgat aaagaaatca ccgaaaaact cagtcaagca ctacagtaaa
    37861 aggttggagg gggctggaca gaaactgaga gttatcgttt ctgtccttct ccctctttaa
    37921 ataaaggagg cagatatgaa tttaaaacaa gctttaattg acaatgactc gatccgacta
    37981 ggtttagagg ctaacaattg gaaagaagca gtcaaggtag cagtagatcc cttaattgaa
    38041 agtggggcaa ttttgccaga gtattacgat gctatcattg aatcgactga agagtatggg
    38101 ccttactata tcttgatgcc aggtatggct atgccccacg ctagacctga agctggtgtg
    38161 caaagtgatg ccttttcatt gattacctta caaaatcctg ttgtattttc agatgggaaa
    38221 gaggtatctg ttttgttggc actagcagca acaagttcaa aaattcacac aagtgtagcc
    38281 attccacaaa ttattgccct gtttgaatta gaagattcta ttgcacgttt acaggcttgc
    38341 cagactaaag aagatgtctt ggctatgatt gaagaatcta aggatagccc ttatctcgaa
    38401 ggattggatt tggaaagtta gaaagaggaa taaagaaatg acaaaaagaa tacctaattt
    38461 acaagttgca ttagaccatt cagacttgca aggagcgatt aaagcagctg tttctgttgg
    38521 tcaggaagta gatattatcg aagctggaac tgtttgcttg cttcaagttg gaagtgaact
    38581 ggctgaagtc ttgcgtagcc ttttcccaga taagattatt gtggcagaca caaaatgtgc
    38641 tgatgctggt ggaacagttg ctaaaaataa tgcggttcgt ggagcagact ggatgacttg
    38701 tatctgttgt gcaaccatcc ctactatgga agcagctcta aaggctatca agactgaacg
    38761 aggagaacga ggcgaaatcc agatcgagct ttatggcgat tggacttttg aacaagctca
    38821 gctttggcta gatgcaggta tctcacaagc tatttatcac caatctcgtg atgctcttct
    38881 tgctggtgaa acttggggtg aaaaagacct taataaggtt aaaaaactca ttgatatggg
    38941 cttccgtgta tctgtaacag gtggtctaga tgtagatact ctcaaactct ttgaaggtgt
    39001 tgatatcttt acctttatcg caggtcgtgg aattacagag gctgcggatc cagcaggagc
    39061 agcgcgtgcc ttcaaggatg aaatcaaacg aatttggggg taaatcatgg tacgtccaat
    39121 tggaatttat gaaaaggcaa ccccaacaca ctttacttgg ctagaacgtt taaattttgc
    39181 caaggagtta ggctttgatt ttatcgagat gtctattgac gaacgtgacg agcgtttagc
    39241 aagacttgac tggagtaagg aagaacgctt ggaagttgtc aaagaaatct atgaaactgg
    39301 tgttcgtatt ccttctatct gtttttcagg ccatcgtcgc tacccattgg gatcaaaaga
    39361 ttcagttcta gaggaaaaat ctctagaact catgaaaaaa tgtatcgaat tagctcaaga
    39421 cttgggagtt cgtacgattc aattagctgg ttacgatgtt tactatgagg aaaagtcacc
    39481 ccagacacgc caacgtttta tcaaaaattt gagaaaagcc tgtgactggg ctgaagaagc
    39541 tcaggtggta cttgctattg aaattatgga tgatcctttc atcagtagca tcgaaaaata
    39601 tttggctata gaaaaagaga ttgactctcc cttcctcttt gtatatccag atattggtaa
    39661 tgtgtctgca tggcataatg atatctatag tgagttttat cttggtcatc atgccatcgc
    39721 agctctccat ctcaaggata cttatgcagt gacagaaagt tcaaagggcc agttccgaga
    39781 tgtacctttc gggcaaggtt gtgtcaaatg ggaagaagct ttcgatattt taaaggaaac
    39841 caattataat ggacctttcc taatcgaaat gtggtctgaa aattgtgaaa cagtagaaga
    39901 aacacgcgca gccattcaag aggcgcaagc ttttctctat ccactcatta agaaagcagg
    39961 tttgatgtaa gatgaatcaa gtaatcaatg ctatgcgtaa acgagtctgt gatgccaatc
    40021 aatcattgcc aaaacatgga cttgtcaaat ttacctgggg gaatgtatct gaagtcaatc
    40081 gcgaactcgg tgtcattgtt atcaaaccat caggcgtgga ttatgacgaa ttgacacctg
    40141 aaaacatggt agtgactgat ctagatggta agatcctaga aggggattta agaccatctt
    40201 ccgacctccc aactcatgtg caattatata aggcttggtc agaaattggt agtgtggttc
    40261 acacccattc gacagaagct gttgcttggg ctcaggcagg tcgtgatatt cctttctacg
    40321 gaacaaccca tgcagattat ttctacggtt caattccttg cgcccgtagt ttgaccaagg
    40381 acgaagtaga agtggcctat gaaaaagata ctggcctggt tatcgtagaa gagtttgaac
    40441 atcgcggact taacccggtt gaagtaccag gaattgttgt acgcaatcac ggtccattca
    40501 cctggggcaa aaatccagag aatgctgttt atcactctgt cgtactagag gaagtatcaa
    40561 agatgaatcg ctttacagaa caaatcaatc caagagttgg acctgctccc cagtacatac
    40621 tagaaaaaca ctaccaacgt aaacatggac caaatgctta ttatggtcaa aagtaagaac
    40681 gatgaaggag gagaaaaaga taaatttagc tcctcttttt acatttgatt tttattgaga
    40741 gtaaagttgg agttgaagta attttaaaag attttttaga aatagcgctt gatatatata
    40801 tggtaaaata aaaagaattg ctgtgatatc aatagatttg ggggattttt taatatggta
    40861 ctggataagg caagttgtga tttgcttcaa tatttgatgg atcaagaaac gtccaaaacg
    40921 attatggcga tttcgaaaga tttgaaagag tcaagaagga aaatttatta tcacattgac
    40981 aaaatcaatg ctgctctggg tgacgaggcg cttcacatca ttagtattcc acgaattggt
    41041 attcacttaa cggaagagca gagagatgct tgttgtaaac tattatcgga agtagattcg
    41101 tacgattata tcatgagtgc gcatgaacgt atgatgataa tgttactatg gataggtatt
    41161 tctaaagaac gtattacgat tgaaaaattg atagagttaa cagaggtatc taggaatact
    41221 gttctcaatg atttgaatag tattcgttat caactaactt tggaacaata tcaggtgatc
    41281 ttgcaagtga gcaagtcaca gggataccac cttcatgccc accctcttaa taaaattcag
    41341 tatcttcaat cgcttctata tcatattttt atggaagaaa atgccacttt tgtatctatt
    41401 ttagaagata agatgaaaga gaggttagat gatgagtgtt tgctttctgt tgaaatgaac
    41461 caatttttta aggaacaggt tcctttagtt gaacaagatt tagggaagaa aataaatcat
    41521 catgaaataa cttttatgtt gcaggttcta ccttatttgc tgttaagctg tcataatgtt
    41581 gaacagtatc aagaaagaca tcaggatata gagaaagaat tttctttgat aagaaaaaga
    41641 atagagtatc aggtgtctaa gaaattagga gaacggttgt ttcaaaagtt tgaaatttct
    41701 ttgtcaggac ttgaagtttc tcttgtagct gttctcctcc tctcctatcg taaagatttg
    41761 gatattcatg cagaaagtga tgattttcgg caattaaaac ttgctttaga agaatttatc
    41821 tggtattttg aatcacaaat ccgaatggag attgagaaca aggatgattt gttacgaaat
    41881 ttgatgatcc actgtaaagc cttgttattt agaaagactt acggtatttt ttctaaaaat
    41941 cctctaacaa aacaaattcg atccaagtat ggagaattat ttttagtcac tagaaaatct
    42001 gcggaaattt tagaaggagc atggtttatt cggctaacag acgatgatat tgcctatttg
    42061 acgattcata ttggaggatt tttaaagtat acaccatcgt ctcaaaaaaa tatgaaaaaa
    42121 gtttatctcg tttgtgatga aggtgttgcg gtttcgagac ttttgctgaa acaatgcaaa
    42181 ctttattttc caaatgagca aattgacact gtatttacaa cagaacaatt taagagtgtg
    42241 gaagatattg cacaagttga tgtagtgatt actactaatg atgatttgga tagcagattt
    42301 ccgattttaa gggttaatcc tatccttgaa gcagaagata ttttgaaaat gctagactat
    42361 cttaaacaca atatatttcg taataagagc aaaagtttca gtgaaaatct ttctagtctt
    42421 atttcgtctt atattgtaga cagcaagttg gctagtaagt tccaagaaga ggttcaaaca
    42481 cttataaatc aagaaatagt agttcaagct tttttggaag atatttgaag gacagtccaa
    42541 tgatgaacac aaacctgtgt ttttcttggt cttttttagt gttttgaagg gtggtatact
    42601 aatctcaaag ataacaatta tatccaaagg aggcaacata tgccaaacgt caaagaaatt
    42661 acaagagagt catggatttt agccactttc ccagagtggg gaacatggtt gaacgaagaa
    42721 atcgaagaag aagtcgtacc tgaaggcaac tttgccatgt ggtggctagg caactgtggt
    42781 acttggatta agacaccagc tggtgctaac gttgtcatgg acctttggtc aaaccgtgga
    42841 aaatcaacca aaaaagtgaa agatatggtt cgtgggcacc aaatggcaaa tatggcaggt
    42901 gttcgtaaat tgcaaccaaa cttgcgtgtt cagccaatgg ttatcgatcc atttgctatc
    42961 aacgaactag actattactt agtttcacac ttccacagtg atcatatcga cccatacaca
    43021 gctgcagcaa ttctcaacaa tcctaagtta gagcatgtta agtttatcgg tccttaccac
    43081 tgtggacgaa tctgggaagg atggggggtt ccaaaagaac gtatcatcgt tgttaaacca
    43141 ggtgacacta tcgaattaaa agatatgaag attcatgcag tagaatcatt tgaccgtact
    43201 tgcttggtaa ctctcccagt gaacggtgct gatgagacag gcggtgaact tgctggcttg
    43261 gctgttacag atgaagaaat ggctcaaaag gctgttaact atatctttga aacaccaggt
    43321 ggaaccatct atcatggtgc agattctcac ttctcaaact attttgcaaa acatggtaaa
    43381 gactttaaaa ttgatgttgc tttgaataac tatggtgaaa atccggtagg tatccaagac
    43441 aaaatgacat ctatcgacct tcttcgtatg gcagaaaatc tgcgtaccaa agtcattatc
    43501 ccagttcact atgatatctg gtctaacttc atggcttcta ctaatgagat tctagaactt
    43561 tggaaaatgc gaaaagatcg cttgcaatac gatttccatc catttatctg ggaagttggc
    43621 ggtaagtaca cttatcctca agatcaacac ttagtagaat accatcatcc acgtggtttt
    43681 gatgattgtt ttgaacaaga ctctaacatt caatttaaag ctttgctata atataaaaat
    43741 attctttgga ggttatccgt atgttgcatg atacggataa ttttcatata atagtaaaat
    43801 agaatgtgtg attcaataat cacctcaaat agaaaggaaa ttctatgtca aatctatctg
    43861 ttaatgcaat tcgttttcta ggtattgacg ccattaataa agccaactca ggtcatccag
    43921 gtgtggttat gggagcggct ccgatggctt acagcctctt tacaaaacaa cttcatatca
    43981 atccagctca accaaactgg attaaccgcg accgctttat tctttcagca ggtcatggtt
    44041 caatgctcct ttatgctctt cttcaccttt ctggttttga agatgtcagc atggatgaga
    44101 ttaagagttt ccgtcaatgg ggttcaaaaa caccaggtca cccagaattt ggtcatacgg
    44161 cagggattga tgctacgaca ggtcctctag ggcaagggat ttcaactgct actggttttg
    44221 cccaagcaga acgtttcttg gcagccaaat ataaccgtga aggctacaat atctttgacc
    44281 actatactta cgttatctgt ggagacggag acttgatgga aggtgtctca agcgaggcag
    44341 cttcatacgc aggtttgcaa aaacttgata agttggttgt tctttatgat tcaaatgata
    44401 tcaacttgga tggtgagaca aaggattcct ttacagaaag tgttcgtgac cgttacaatg
    44461 cctacggttg gcatactgcc ttggttgaaa atggaacaga cttggaagcc atccatgctg
    44521 ctatcgaaac agcaaaagct tcaggcaagc catctttgat tgaagtgaag acggttattg
    44581 gatacggttc tccaaacaaa caaggaacta atgctgtaca cggcgcccct cttggagcag
    44641 atgaaactgc atcaactcgt caagccctcg gttgggacta cgaaccattt gaaattccag
    44701 aacaagtata tgctgatttc aaagaacatg ttgcagaccg tggcgcatca gcttatcaag
    44761 cttggactaa attagttgca gattataaag aagctcatcc agaactggct gcagaagtag
    44821 aagccatcat cgacggacgt gatccagtcg aagtgactcc agcagacttc ccagctttag
    44881 aaaatggttt ttctcaagca actcgtaatt caagtcaaga tgccttgaat gttgtggcag
    44941 ctaaattacc aaccttccta ggtggatcag ctgaccttgc tcactcaaac atgacttata
    45001 tcaagacgga tggacttcaa gacgatacca atcgcttgaa tcgtaacatt cagtttggtg
    45061 ttcgtgaatt tgcaatggga acaatcttga acgggatggc ccttcatggt ggacttcgtg
    45121 tatacggtgg aactttcttc gtcttctctg actatgtgaa ggcagctgtc cgcttgtcag
    45181 ccttacaagg acttcctgtg acttatgtct ttacccatga ttcaatcgca gttggggaag
    45241 atggtccgac tcacgaaccg gttgagcatt tagcaggtct tcgtgctatg ccaaatctaa
    45301 atgttttccg tccagcagat gcgcgtgaaa cgcaagcagc ttggtacctt gcagtgacaa
    45361 gtgagaaaac accaactgcc cttgtcttga cacgtcaaaa cttgactgtt gaagatggaa
    45421 cagacttcga caaggttgct aaaggtgctt atgttgtata tgaaaatgca gccgactttg
    45481 ataccatctt gattgcgaca ggttcagagg ttaatcttgc tgtctcagct gctaaagaat
    45541 tggctagtca aggcgaaaaa atccgcgtag tcagcatgcc atctacagat gtctttgata
    45601 aacaagatgc agcttacaag gaagagattc ttccaaatgc agtccgccgt cgtgttgcag
    45661 tcgaaatggg tgcaagtcaa aactggtaca aatatgttgg tctcgatggt gccgttctag
    45721 gtattaatac cttcggagcc tctgccccag caccaaaagt attggcagaa tatggcttta
    45781 ctgtagaaaa tcttgtaaaa attgttcgaa acttgaaata atcctaaaaa tcagggcgta
    45841 agctctggtt tttcttacca gaaaagtaag gtacaatctt gtaaaagtag ctgaaatttg
    45901 atatagtagt cctatgtaaa agacaaagga gaaagcaatg aatccaaata ttactttttt
    45961 aatcatgctt gtaggtatga tggccttgat gttctttatg caacgttctc aaaagaaaca
    46021 agctcaaaag cgtatggaaa gcttaaataa actacaaaaa ggctatgaag tgattacaat
    46081 cggtggactt tatggaacag tcgatgaagt agatacggag aagggaacaa tagttcttga
    46141 cgtagatgga gtttacttga cttttgaact agctgctatc aagacagtat taccgctgaa
    46201 agaaacagct tcactagaag gcgcaattga aaaataagac gggatcacga actcccgttt
    46261 ttctataaaa gaaaggaaat gggatgaaaa aattagtctt tgtctgtctg ggaaatattt
    46321 gccgtagccc tatggccgag tttgttatga aatcaatgac agataactac gaaatccaaa
    46381 gtcgagcaac ttcctcttgg gaacatggca atccgattca taaggggact cagggaattt
    46441 ttcaagagta tgagattcct tatgacaaga acaagacatc gcttcagatt agtaaggaag
    46501 attttgaagc ctttgattat attatcggaa tggacgcttc aaatatttct gacttacgtc
    46561 agatgtgtcc agtagactgt caagataaga tttactcatt ttcatctgaa agtgttccag
    46621 acccttggta tacaggagat tttgaagaaa cctatcgacg tgttcaagag ggctgtcaag
    46681 cttggttaga acgtttagaa aaggagagtt aaggtggaaa atcttacgaa tttttacgaa
    46741 aagtatcgtg tctatctgac tcgtccacga ttagagcttt tggcagtagt taccattgtt
    46801 ttctgtgctg tactcgtctt ttttctaaat attccaggaa aaggtgtctt aaaactcgat
    46861 aatggaacga ttgtttatga tggcagtctt gtccgtggta aaatgaatgg tcaaggtacc
    46921 attaccttcc aaaatggaga ccaatataca ggtggcttca acaatggagc cttcaacgga
    46981 aaaggtacct ttcaatctaa agaaggctgg acctacgaag gtgattttgt aaatggtcag
    47041 gctgaaggaa aagggaaact aacaacagaa caagaagtcg tttatgaagg aacttttaaa
    47101 caaggcgttt ttcaacaaaa ataaagcctc cttatcaaag gaggtattat tagaatcgca
    47161 aggtaagcgc ttacctgcaa atccctttct ttccaaatcc ctcttccaac caagtttgtg
    47221 aaataaaaaa tatttgaaat aaatttcaca aacttcaaag ataaaacctg ataagaaaag
    47281 aaaatgagaa aagtttcaca agagtttaaa aattctttgt gaaatgttta tgaaactgtt
    47341 tacaaagttg aaataatgcg ttataataaa cttgtgaaaa aattaacaaa ggatatcgtt
    47401 ccttgaaagc tatggaggaa aatatggctg ataaaaaaac tgtgacacca gaggaaaaga
    47461 aactcgttgc tgaaaaacac gtagatgagt tggttcaaaa agctctagtt gcccttgaag
    47521 aaatgcgtaa attggatcaa gaacaagttg actacatcgt tgccaaagca tcagtagcag
    47581 ctttggatgc ccacggagaa ttggctttac atgcctttga agaaacagga cgtggtgtat
    47641 ttgaagataa agcaactaag aacttgtttg cttgtgaaca cgtggtaaac aacatgcgtc
    47701 acactaaaac agttggcgtt atcgaagaag atgatgtaac aggattgacc ctgattgctg
    47761 aaccagttgg tgttgtttgt ggtatcactc caacaacaaa cccaacatca acagcgatct
    47821 tcaaatcatt gatttcattg aagacacgta atccaatcgt ctttgccttc catccatcag
    47881 ctcaagaatc atcagttcat gcagctcgta tcgtccgcga tgcagctatc gcagctggtg
    47941 ctcctgaaaa ctgtgtacag tggatcactg aaccatctat ggaagcaact agtgccctta
    48001 tgaaccacga aggtattgca acaatccttg caacaggtgg taatgccatg gttaaagccg
    48061 catactcatg tggtaaacca gctcttgggg taggtgccgg aaacgttcca gcttatgttg
    48121 aaaaatcagc aaacattcgt caagcagcac acgatatcgt catgtctaaa tcatttgata
    48181 acggtatggt ctgtgcatct gaacaagcag ttatcattga taaagaaatt tacgatgaat
    48241 ttgtagcaga gttcaaatct taccacactt actttgtaaa caaaaaagaa aaagctcttc
    48301 ttgaagagtt ctgcttcgga gtcaaagcaa acagcaaaaa ctgtgctggt gcaaaattga
    48361 acgctgacat cgttggtaaa ccagcaactt ggattgcaga acaagcagga tttacagttc
    48421 cagaaggaac aaacattctt gctgcagaat gtaaagaagt tggcgaaaat gagccattga
    48481 ctcgtgaaaa attgtcacca gttattgcag ttttgaaatc tgaaagccgt gaagatggta
    48541 ttactaaggc tcgtcaaatg gttgaattta acggtcttgg acactcagca gctatccaca
    48601 cagctgacga agaattgact aaagaatttg gtaaagctgt taaagctatt cgtgttatct
    48661 gtaactcacc ttctactttt ggtggtatcg gggacgttta caatgccttc ttgccatcat
    48721 tgacacttgg atgtggttct tacggacgca actcagttgg ggataacgtt agtgccatta
    48781 acctcttgaa tatcaaaaaa gtcggaagac ggagaaataa catgcaatgg atgaaacttc
    48841 cttcaaaaac atactttgaa cgtgattcaa ttcaatacct tcaaaaatgt cgtgacgttg
    48901 aacgtgtcat gatcgttact gaccatgcca tggtagagct tggtttcctt gatcgtatca
    48961 tcgaacaact ggaccttcgt cgcaataagg ttgtttacca aatctttgcg gatgtagaac
    49021 cggatccaga tatcacaact gtaaaccgtg gtactgagat tatgcgtgcc ttcagaccag
    49081 ataccatcat cgcactcggt ggtgggtctc caatggatgc tgccaaagta atgtggctct
    49141 tctacgagca accagaagtg gacttccgtg accttgtcca aaaattcatg gatatccgta
    49201 aacgtgcctt caagttccca ttgcttggta agaagactaa attcatcgcg attccaacta
    49261 catctggtac aggatctgaa gtaacaccat ttgccgttat ctctgataaa gcaaacaacc
    49321 gtaaataccc aatcgctgac tactcattga caccaactgt ggcaattgta gaccctgctt
    49381 tggtattgac agttccagga tttgttgctg ctgatactgg tatggacgta ttgactcacg
    49441 cgacagaagc atacgtatca caaatggcta gtgactacac tgatggttta gcacttcaag
    49501 ctattaaatt ggtctttgaa aatctcgaaa gctcagttaa gaatgcagac ttccactcac
    49561 gtgagaaaat gcataacgct tcaacaatcg ctggtatggc ctttgccaat gccttcctag
    49621 gtatttctca ctcaatggcc cataagattg gtgcgcaatt ccacacaata cacggtcgta
    49681 caaatgctat cttgcttcca tacgttatcc gttacaacgg tacacgtcca gctaagacag
    49741 caacatggcc taagtacaac tactaccgtg cagatgaaaa ataccaagat atcgcacgca
    49801 tgcttggact tccagcttct actccagaag aaggggttga atcttacgca aaagctgtct
    49861 acgaactcgg tgaacgtatt gggatccaaa tgaattttag agaccaagga attgacgaaa
    49921 aagaatggaa agaacattct cgtgaattag ccttcctggc ttatgaagac caatgttcac
    49981 cagctaaccc acgtcttcca atggtagacc atatgcaaga aatcatcgaa gatgcatact
    50041 atggctacaa agaaagacca ggacgccgta aataattgtt tatcagtcta gaagcaagac
    50101 aaaaactcaa tttgagggaa agatccagta atttttctat gataaaaggc atcctatcaa
    50161 ggtttttgaa cacctgatag gatgcctttt tatgatattg aggccttttt gccctttttg
    50221 aaaaactaga atagaaacaa aatatataat agattgaaac tggaatagta cacttctgct
    50281 tctaaaaaat tgttagaatt cgatttgact gtcctgatcg atttgtccta ttcctatttc
    50341 attttattat ataaaaaata tagtatagta gactgaatct aaaatagtac gaaacaattg
    50401 ctaaaacatt tatagaaatt aatt
//
LOCUS       DAVHKZ010000010        48570 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000010 DAVHKZ010000000
VERSION     DAVHKZ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48570
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.010"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(175..1161)
                     /locus_tag="VVO74_000748"
     CDS             complement(175..1161)
                     /locus_tag="VVO74_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU5694795.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1171..1971)
                     /locus_tag="VVO74_000749"
     CDS             complement(1171..1971)
                     /locus_tag="VVO74_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU5694796.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2224..3066)
                     /locus_tag="VVO74_000750"
     CDS             complement(2224..3066)
                     /locus_tag="VVO74_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU5694797.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(3068..4360)
                     /locus_tag="VVO74_000751"
     CDS             complement(3068..4360)
                     /locus_tag="VVO74_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU5694798.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4471..5742)
                     /locus_tag="VVO74_000752"
     CDS             complement(4471..5742)
                     /locus_tag="VVO74_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU5694799.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6291..7808
                     /gene="malQ"
                     /locus_tag="VVO74_000753"
     CDS             6291..7808
                     /gene="malQ"
                     /locus_tag="VVO74_000753"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU5694800.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            7834..10092
                     /gene="glgP"
                     /locus_tag="VVO74_000754"
     CDS             7834..10092
                     /gene="glgP"
                     /locus_tag="VVO74_000754"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEU5694801.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYKVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11137..11709)
                     /locus_tag="VVO74_000755"
     CDS             complement(11137..11709)
                     /locus_tag="VVO74_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694802.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLTQLWDKNDAIPNNGRINF"
     gene            complement(12334..13182)
                     /locus_tag="VVO74_000756"
     CDS             complement(12334..13182)
                     /locus_tag="VVO74_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU5694803.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            13334..13612
                     /locus_tag="VVO74_000757"
     CDS             13334..13612
                     /locus_tag="VVO74_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694804.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            13614..15677
                     /locus_tag="VVO74_000758"
     CDS             13614..15677
                     /locus_tag="VVO74_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU5694805.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(15755..17011)
                     /locus_tag="VVO74_000759"
     CDS             complement(15755..17011)
                     /locus_tag="VVO74_000759"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU5694806.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            17153..19618
                     /locus_tag="VVO74_000760"
     CDS             17153..19618
                     /locus_tag="VVO74_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU5694807.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLCFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLATADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            19683..20594
                     /locus_tag="VVO74_000761"
     CDS             19683..20594
                     /locus_tag="VVO74_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU5694808.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            20824..21522
                     /gene="dapD"
                     /locus_tag="VVO74_000762"
     CDS             20824..21522
                     /gene="dapD"
                     /locus_tag="VVO74_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU5694809.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            21590..22720
                     /locus_tag="VVO74_000763"
     CDS             21590..22720
                     /locus_tag="VVO74_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU5694810.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDDAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            22732..23271
                     /locus_tag="VVO74_000764"
     CDS             22732..23271
                     /locus_tag="VVO74_000764"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU5694811.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVAYDPQQLVKTSFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            23255..23932
                     /locus_tag="VVO74_000765"
     CDS             23255..23932
                     /locus_tag="VVO74_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU5694812.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(23999..24898)
                     /gene="galU"
                     /locus_tag="VVO74_000766"
     CDS             complement(23999..24898)
                     /gene="galU"
                     /locus_tag="VVO74_000766"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU5694813.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(24920..25936)
                     /locus_tag="VVO74_000767"
     CDS             complement(24920..25936)
                     /locus_tag="VVO74_000767"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU5694814.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            26148..26588
                     /locus_tag="VVO74_000768"
     CDS             26148..26588
                     /locus_tag="VVO74_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU5694815.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDK
                     IFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW"
     gene            complement(26711..27127)
                     /locus_tag="VVO74_000769"
     CDS             complement(26711..27127)
                     /locus_tag="VVO74_000769"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5694816.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTA"
     gene            complement(27195..27845)
                     /gene="phoU"
                     /locus_tag="VVO74_000770"
     CDS             complement(27195..27845)
                     /gene="phoU"
                     /locus_tag="VVO74_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU5694817.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(27860..28612)
                     /gene="pstB"
                     /locus_tag="VVO74_000771"
     CDS             complement(27860..28612)
                     /gene="pstB"
                     /locus_tag="VVO74_000771"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU5694818.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(28614..29429)
                     /gene="pstA"
                     /locus_tag="VVO74_000772"
     CDS             complement(28614..29429)
                     /gene="pstA"
                     /locus_tag="VVO74_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU5694819.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDIMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(29422..30285)
                     /gene="pstC"
                     /locus_tag="VVO74_000773"
     CDS             complement(29422..30285)
                     /gene="pstC"
                     /locus_tag="VVO74_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU5694820.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(30403..31278)
                     /locus_tag="VVO74_000774"
     CDS             complement(30403..31278)
                     /locus_tag="VVO74_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEU5694821.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(31445..32776)
                     /locus_tag="VVO74_000775"
     CDS             complement(31445..32776)
                     /locus_tag="VVO74_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU5694822.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(32777..33484)
                     /locus_tag="VVO74_000776"
     CDS             complement(32777..33484)
                     /locus_tag="VVO74_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5694823.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(33568..34053)
                     /locus_tag="VVO74_000777"
     CDS             complement(33568..34053)
                     /locus_tag="VVO74_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU5694824.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            34039..34578
                     /locus_tag="VVO74_000778"
                     /pseudo
     CDS             34039..34578
                     /locus_tag="VVO74_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(34893..36584)
                     /locus_tag="VVO74_000779"
     CDS             complement(34893..36584)
                     /locus_tag="VVO74_000779"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU5694825.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            36720..37166
                     /gene="argR"
                     /locus_tag="VVO74_000780"
     CDS             36720..37166
                     /gene="argR"
                     /locus_tag="VVO74_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU5694826.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            37217..39751
                     /gene="mutS"
                     /locus_tag="VVO74_000781"
     CDS             37217..39751
                     /gene="mutS"
                     /locus_tag="VVO74_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU5694827.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            39898..41592
                     /gene="patA"
                     /locus_tag="VVO74_000782"
     CDS             39898..41592
                     /gene="patA"
                     /locus_tag="VVO74_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEU5694828.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEVIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(41922..42185)
                     /locus_tag="VVO74_000783"
                     /pseudo
     CDS             complement(41922..42185)
                     /locus_tag="VVO74_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            42379..44145
                     /gene="patB"
                     /locus_tag="VVO74_000784"
     CDS             42379..44145
                     /gene="patB"
                     /locus_tag="VVO74_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU5694829.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTENKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            44284..44973
                     /locus_tag="VVO74_000785"
     CDS             44284..44973
                     /locus_tag="VVO74_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU5694830.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQIGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            44977..45156
                     /locus_tag="VVO74_000786"
     CDS             44977..45156
                     /locus_tag="VVO74_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694831.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            45143..46492
                     /locus_tag="VVO74_000787"
     CDS             45143..46492
                     /locus_tag="VVO74_000787"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU5694832.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            46616..48076
                     /locus_tag="VVO74_000788"
     CDS             46616..48076
                     /locus_tag="VVO74_000788"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU5694833.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYSRHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            48090..48524
                     /locus_tag="VVO74_000789"
     CDS             48090..48524
                     /locus_tag="VVO74_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU5694834.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT        14307 a         9231 c        10550 g        14482 t
ORIGIN      
        1 ggctagcttc ctagtttgca ctttgatttt cattgagtat aaaaagatct tgggtaacaa
       61 ctcaatttca gtagaaaagg aagtaaatct tcccacaata aaacgcatag tatcaagttt
      121 tttcaatacc tgatactatg cgtttttgct tttaacgact ttttgcccag tctcttattt
      181 ttcgataatt ttgtgggcga tcaattgacg gtaacaaatt tgtttattgt ttttattatc
      241 attaataatc tggagaatag tttcaaggga aacacgacca agctctaaac tattgatatc
      301 gacataggct gccaagttga gcttgggatt aaccgagtca aagctgagaa cagggacatc
      361 cagctggtgt ttggcaatat agttacaaac accttcagct aggaggctat cggttgtgat
      421 gatagcatca atttgtggat cgtgcttgaa taatcgcttg ctaaatttat agcccttttc
      481 ttccagaaac tcgtcggcaa agtagatgcg attgttgtca gtggtaagtt tgtaatgttt
      541 aagcgcctgt tcatagcctg ttaaacggtc tttggtcacg aagagctttt tacttcctcc
      601 gataaaggca atgcgtttgc agcctttttt gatgaaatat tcagtcgcat caaaaccagc
      661 ttgaacattg tcgttgtcga caagtgggat gaaaggagat agagatttac ctaagataag
      721 gaaggggaac tgttcttctg cgacgagttt tacgagaggg tcttcttctt gggcatagag
      781 aaagattagc ccatctacac gcttgccgta gaccatttgt gaaatagcgt tgagacgctc
      841 cttctcatct ttccctgttg ctatctgaat ggcatagtgg ttttcagatg cgacttgaga
      901 gatgccacgt agaaccgatg gaaagaaagg attctggtag aaggcgtctg agtcatcagg
      961 aagaactaat ccgataacct gagtatagct gcttaccaag ctacgagcgt tgaggtttgg
     1021 gtggtagttg agttccttca tagctttgcg aacgcgtttt tttgtttcgt cgctaatggt
     1081 tgatttattt tgaataacac gggttacggt tgaaggcgaa acaccagcag ccttggccac
     1141 gtctttaatc gtaacgggca taaaaatctc ctatttatgg taatttggat cacggaaatg
     1201 tgttttataa aagatagtga ccagatacag aacaaaaaga atattttgta cagtaatcag
     1261 ggttgtcata ttttggccaa ataatcccaa aataagtgta atcagagtcg gcaatcctaa
     1321 acagttcaag ataaagtgat agcactcttt aaaggttcta aatgaaaaga ggcgtgattt
     1381 cttagtgata taaaggagaa gactagctcc tagagagacg ataaagaaat tcaaaccaaa
     1441 gaggaagctc gcaccgagaa ctaggaagag gctgatatag acacgatttt gttggtacca
     1501 gtctttagaa attgcttggg tcaagctgtc tttgcttttg aaactctcag tctgaatggc
     1561 tcggtaagag atgcgggtca gttccttgct ttccttgctg atgactagct catttgtatc
     1621 gaaatgcagt tgcaagtcct taggtaattc cttgatttga cttggaccaa tcacaacaga
     1681 aggggcttga ctagctgttc cagtataagt taatgtgcca tcgacaattg tagcatgttc
     1741 agagagatcc tggacaacct catttgtcag aggttcatag acattatcga taaaagtttc
     1801 tagcggatag gtctcctggg agctgttttg gatagcaatg ggtaccatag acaagctgat
     1861 aaggaagata ctggtaaaga gaagttgaaa ccagttgagc tcgaaacgtt tggacagggg
     1921 cttacgaaac ccccaaatac ttgaaaaata ggaaaatgga tatggaagca taggtatctt
     1981 tctaaaaggt gttttctata tgagtattat tatatagaga aatgctcttt atttcaagtc
     2041 taggagaaaa attgcttgct acaaggatat tatttacagt gacaattgct aataatcaat
     2101 gaaaatcaaa gtgcaaacta gccacaggtt gctcaaagca caactttgag gttggagata
     2161 aagctgacgt ggtttgaaga gattttcgaa gagtataaaa tgaaaaaggg tggcggggat
     2221 aaattatccc ttgtcgccac cacttgtaag tcctgaaaca aagttctttt gtaggaagaa
     2281 gaagagaata cagattggaa gggcgatgag gatagcacct gctgagaagt aggcaatctt
     2341 caagtttttc gcattgttaa cgaaggtttg gagacctacg gcaacagtaa agtattcttt
     2401 ctcacgaagc aagaaactag agaggatgta gtccccgaaa ggtcccatga aggcccagag
     2461 agcttgtacg gcaaccattg ggcgaacaag tggtagaaca atttgccaga agcggcggaa
     2521 gtgtcctgca ccgtctagtt ttgcagattc gtctaaagac attggcactg tatcgaagta
     2581 gcctttcatg agccaagcat tcatcgggat accaccacca acgtagagga agatgaggaa
     2641 ccagttgtgg ttaagggcgt tcaacataag cgccataacg aagaaggctg tcaaagcggc
     2701 catagttggc accatttgga tgatcaagaa gaagaccaaa ctttgtttac gagccaagaa
     2761 gttgtaacgg ctgtaggcat aaccagcaag tacgatgata cttgtttgaa cagccatggt
     2821 aattaaggcg ataatcaaag tgttgaggta ccaagtaccg tacaaggttt cagtgaagag
     2881 gcctttaaag ttatcaaaat tgaggtcgat attagtatct agtttaaagg ctgagacgtt
     2941 acctgcttta aaggctgaca taatggtaat caacagtgga tagataatta caattgatag
     3001 accaatcagg taaaggtaag taaggctttg agtcagtcta cgtttgagtt taattgagtt
     3061 attcatctta gacgtcctcc atatcaaatg cgtgtagttt cttgaatgcg atcatagaga
     3121 ttgagatgac aatgatagag ataatcaagg taacagctgc cgccattgag tattgaggag
     3181 atgtacctgt tgtcaaacgg tagatccatg agatcaagat atcggttgaa ccagctccac
     3241 ctccgacact accaggtcct ccaccattga agaggtacat gatagagaag ttgttaaagt
     3301 tgaaggtgta ttggctaatc aaagtaggtg ccgcaacagc caaaatcatt gggaaagtga
     3361 tgttgcggaa tttttgccaa gcgttggcac cgtcaatata agctgcttcg taaaggtcgt
     3421 taggaataga ttgcaagata cccaaagtca aaacgtagat gtatgggaat ccgagccaac
     3481 cttgcatcat aatcaaggca atcttagtcc aagttgggtc tgttttccaa ggaataagag
     3541 ctccatcaag gaaaggaagg aatttagcca agattggcaa tacttgagtg ttgatagcac
     3601 cgacactatc gttaaacatg tttgagaatg tcaagatagt gatgaaggct gggacagccc
     3661 aaggaagaag gaaaataaca ccaaagatac gttttccttt gataaatggt tggttggcaa
     3721 tgatagctgt gaagatacca attacgattt gtaaagtaga agctgccaaa gcccaaatga
     3781 tagtccaaga aagaacagaa ccaaaggcag aacggaaggt actcaagctc caaatgtttg
     3841 taaagttggt caaaccaacc cagtccaaca acttgtttgg tggcaagtgt tggaagtcgt
     3901 agttggtaaa ggcgatcatc aaggttacga taactgggaa gataatcgcg aaggtcatgg
     3961 caacataaga tggaatgatc aagaggtaag ggaagccatt ttcataaatc cctttgatca
     4021 tgtctttgag tgtgcgtgga actggaattc cattgttaat gcgttttgca atcgtatgtg
     4081 catctttgat atttgagaaa taaaagagta cataaacgat tacaaagatt agatggaagg
     4141 caccacgaat cagcataaag agggaattat cacgacctgg tttgtcacca agagtgatga
     4201 ggttgctcaa ttcaggggtt gcaagtgcta ggaagtaaag gacaaatacg atggttacac
     4261 caaggaagat aaaacctttg gctttttgtt tattgtaaat ctgtcctaac ccaggaatga
     4321 tagacagcag ggctgcttta ctaggttgtt gcttttccat attaactcct ttcataggat
     4381 actacttttt tataagaaag ctaaattatt tgtgtctcta ttgataaatt caaaggggga
     4441 tttgatttcc accccccttg aacaaatttt ttattcacca aatttttgtt tgattgtttc
     4501 tttgatcaat gttacagcat cgttagcagc tgttttagca tctttttgac cacttacagc
     4561 atcaaagagc atatttttcg ctggatccca aactgcagac atttgagaga tgtttggcag
     4621 tggttgagtg ttcttgaact gtttgataac agctgttgtc aactcatcgt ttttaccttc
     4681 agcgtatgaa cgagcctcag tattagctgg gatttcgtta gtcttatcat ataatacttt
     4741 ttgttgttca gttgcaacaa ggaagtctac aaatttttga gaagcttcaa ggttcttaac
     4801 ggcttgagga atgacccaag ctttaccacc accgaatgca gcatattctt ttccatttgg
     4861 aagagttggg atagttgcaa ctccgtagtt tactttagca tctttaaagg cttgagcttt
     4921 ccaaggtccg tcgatgatag cagctgtttt accttcttgg aattgagttt ggattaagtt
     4981 tccagcacct tctgtatctt gcataccttt aggccatttt tcgtaccaag atttagcgta
     5041 gttgatacct gcgatagaac cgtcgtttgc aagaccgatg tctttagcgt ctttaccgtt
     5101 ttggccaaag acgtaagcac cgttaccggc aagaagtcca tatgtatagt agaagtttgt
     5161 ccagtcagct aggaaggcag tagttttacc atcttcacca gcgaatgcgt atttgctatc
     5221 tttagcaagg ttttccaagt cagcaaatgt ttttggagca tctttcacca agtctttgtt
     5281 gtagtacata acaagtgact cgataacggc aggagcaccg taaactttac cattagcagc
     5341 tgttacaaga gatttagttg tgtcgtctgt tttagcacca tcgctcaatt tcacttctga
     5401 aagttgtccg tcagaaccaa ggctacctac acggtcgtat ggagccatca taacatcagg
     5461 gacattacca gattggttgt caagagaaag tttatcaaga cctcctagag catcaccagt
     5521 tttaagagtg acttttactc cagcttcttt ttcataagct ttagcaacct cttcaatata
     5581 gctcttatat ccctcgtcta catatacagt gagttctttg acttcagatg aaccagaatc
     5641 agcaggctta tcagcagttt tgcttccgca agctaccaaa agcaagctag caagtgtagc
     5701 agttccaagc accgcagtgc tcttcataaa tttagatgac atagtgtatt cctcctaaag
     5761 aatagcaagt tttattgata aggaaacgca aacgttttcc tttatgagct tagtatagca
     5821 caaatagaaa acggttgcaa gtattttttg taaaaatttt aaaaaatttt taagcttgat
     5881 ttgatagtat aattttgcat tttaatagaa gaaaagtatg aaatagataa gaatacagta
     5941 tttttaataa aaatatatgg aatctgtcta aagagggaaa tcaggagggg tacctccctg
     6001 tttctaatct atatctattt tctatagacg tttgtgcttt gttgcatata aattcaagct
     6061 ccctaaggag gttttgtact ttgtatactg tctcgtgaga gtcaaacttt aggattagat
     6121 agttttaagt tatctttgct aaaatgagtt agtctcctta aaaataatca aaaaagtttt
     6181 ttaaaaacgc ttgcaattat gcttgaaaag gagtatactt ataagtaacg caaacgtttg
     6241 cgtctgaaaa atacgcaacg ttccattatt ttaacacacg aggtgctatt atgaaaaaac
     6301 gtcaaagtgg tgtgttgatg cacatctctt ctcttccagg agcttacgga atcggatcat
     6361 ttggtcaaag tgcttacgac ttcgttgatt tcttggtccg tacaaaacaa cgttactggc
     6421 aaatccttcc attaggagca actagttacg gggattctcc ttaccaatct ttctcagcct
     6481 tcgcaggaaa cactcatttt atcgatttag atatcttggt ggagcaaggt ttgttggaag
     6541 caagtgacct tgaaggagtt gactttggta gcgatgcgtc tgaagttgac tatgctaaaa
     6601 tctactatgc acgtcgtcct cttttagaaa aagcggtgaa acgtttcttt gaagtcggag
     6661 atgttaaaga ttttgagaaa tttgctcaag acaaccaatc atggcttgag ctctttgctg
     6721 agtatatggc tatcaaagag tattttgaca atcttgcttg gactgaatgg ccagatgcag
     6781 atgctcgtgc tcgtaaagct tcagcacttg aaagctatcg tgagcaattg gcagacaagt
     6841 tggtttacca ccgtgtgact caatacttct tcttccaaca atggttgaaa ttgaaagctt
     6901 acgctaacga caaccacatc gaaatcgttg gggacatgcc aatctacgta gcggaagatt
     6961 caagtgatat gtgggcaaat ccacatctct tcaaaacaga tgtcaatggt aaggctactt
     7021 gtatcgcagg atgcccacca gatgagtttt ctgtaactgg tcagctttgg ggtaatccaa
     7081 tctatgactg ggaagcaatg gacaaagacg gctacaaatg gtggattgaa cgcttgcgtg
     7141 aaagcttcaa aatctacgat atcgttcgta tcgaccactt ccgtggcttc gaatcttact
     7201 gggaaatccc tgctggttcc gatacagcag cacctggtga gtgggtgaaa ggtccaggct
     7261 acaagctttt tgcagccgtt aaggaagaac ttggtgagct aaacatcatc gcagaagacc
     7321 ttggcttcat gacagatgaa gtgatcgaat tgcgtgaacg tactggcttc ccaggaatga
     7381 agattcttca atttgccttc aacccagaag acgaaagcat tgatagccca cacttggcac
     7441 ctgctaactc agttatgtac acaggaacac acgataacaa tacggttctt ggttggtacc
     7501 gtaatgagat tgatgatgcg actcgtgagt acatggctcg ttacacgaac cgtaaagaat
     7561 acgaaacagt ggtacacgct atgcttcgta cagtattttc atcagttagc tttatggcaa
     7621 ttgcaactat gcaagattta ctagaattgg atgaggcagc tcgtatgaac ttcccatcta
     7681 cccttggtgg aaactggtct tggcgtatga ctgaagatca attgacacca gctgtcgagg
     7741 aaggtttgct tgacttgaca acaatttatc gccgaattaa tgaaaatttg gtagatttaa
     7801 agaaataaga caataatcag gagacaacta aacatgttat cactacaaga atttgtacaa
     7861 aatcgttaca ataaaaccat tgcagaatgt agcaatgaag agctttacct tgctcttctt
     7921 aactacagca agcttgcaag cagccaaaaa ccagtcaaca ctggtaagaa aaaagtttac
     7981 tacatctcag ctgagttctt gattggtaaa ctcttgtcaa acaacttgat taaccttggt
     8041 ctttacgacg atgttaaaaa agaacttgca gctgcaggta aagacttgat cgaagttgaa
     8101 gaagttgaat tggaaccatc tcttggtaat ggtggtttgg gacgtttggc tgcctgcttt
     8161 atcgactcaa ttgctactct tggtttgaat ggtgacggtg ttggtcttaa ctaccacttt
     8221 ggtcttttcc aacaagttct taaaaacaac caacaagaaa caattccaaa tgcatggttg
     8281 acagagcaaa actggttggt tcgctcaagc cgtagctaca aagtaccatt tgcagacttt
     8341 actttgacat caactcttta cgatattgat gttactggtt atgaaacagc gactaaaaac
     8401 cgcttgcgtt tgtttgactt ggattcagtt gattcttcta ttattaaaga tggtatcaac
     8461 tttgacaaga cagatatcgc tcgcaacttg actctcttcc tttacccaga tgatagtgac
     8521 cgtcaaggtg aattgctccg tatcttccaa caatacttca tggtttcaaa cggtgcgcaa
     8581 ttgatcatcg acgaagcaat cgaaaaagga agcaacttgc atgaccttgc tgactacgca
     8641 gttgtccaaa tcaacgatac tcacccatca atggtgattc ctgaattgat tcgtcttttg
     8701 actgcacgtg gtatcgatct tgacgaagca atttcaattg ttcgtagcat gactgcctac
     8761 actaaccaca caatccttgc tgaagcgctt gaaaaatggc ctcttgaatt cttgcaagaa
     8821 gtggttcctc acttggtacc aatcatcgaa gaattggacc gtcgtgtgaa ggcagagtac
     8881 aaagatccag ctgttcaaat catcgatgag agcggacgtg ttcacatggc tcacatggat
     8941 atccactacg gatacagtgt taacggggtt gcagcactcc atactgaaat cttgaaaaat
     9001 tctgagttga aagccttcta cgacctttac ccagaaaagt tcaacaacaa aacaaacggt
     9061 atcactttcc gtcgttggct tatgcatgct aacccaagat tgtctcacta cttggatgag
     9121 attcttggag atggttggca ccatgaagca gatgagcttg aaaaactttt gtcttatgaa
     9181 gacaaagcag ctgtcaaaga aaaattggaa agcatcaagg ctcacaacaa acgtaaattg
     9241 gctcgtcact tgaaagaaca ccaaggtgtg gaaatcaatt caaattctat ctttgatatc
     9301 caaatcaaac gtcttcacga gtacaaacgc caacaaatga acgctttgta cgtaatccac
     9361 aaataccttg acatcaaagc tggtaacatc cctgctcgcc caattacaat cttctttggt
     9421 ggtaaagcag ctccagccta cacaatcgct caagatatca ttcacttgat cctttgcatg
     9481 tcagaagtta ttgctaacga tccagcagta gctccacact tgcaagtagt tatggttgaa
     9541 aactacaacg ttactgcagc aagcttcctt atcccagcat gtgatatctc agaacaaatc
     9601 tcacttgctt ctaaagaagc ttcaggtact ggtaacatga aattcatgtt gaacggagct
     9661 ttgacacttg gtactatgga cggtgctaac gtggaaatcg ctgagttggt tggagaagaa
     9721 aacatctaca tcttcggtga agattcagaa actgttatcg acctttacgc aaaagcagct
     9781 tacaaatcaa gcgaattcta cgctcgtgaa gctatcaaac cattggttga cttcatcgtt
     9841 agtgatgcag ttcttgcagc tggaaacaaa gagcgcttgg aacgtcttta caatgaattg
     9901 atcaacaaag actggttcat gactcttctt gacttggaag actacatcaa agtcaaagag
     9961 caaatgcttg ctgactacga agaccgtgac gcatggttgg ataaagtcat cgttaacatt
    10021 tctaaagcag gattcttctc atctgaccgt acaatcgctc agtataatga agacatctgg
    10081 cacttgaact aatactcttc gaaaatctct tcaaaccacg tcagctttat ctgcaacctc
    10141 aaagcggtgc tttgagcaac ctgcggctag cttcctagtt tgctctttga ttttcattga
    10201 gtataagatg caaatttata ctaatacatt ttgtaaaaaa gcgagtttcg attgaaattc
    10261 gcttttttaa atgctgtgga tttgggtcaa tcttgtctaa aaatagggaa atcctagata
    10321 cagtgaaggc tttaaatgct ggtttttact gtcttcagcc ttatattttt tcgtagttgg
    10381 ttacctcata tctcttgtat tcgcttacat aaagtattat aatataattg taggaaagaa
    10441 ggtgttttta tgatatacac acttaaattg gtgttgttta ttacctttct tgtaataagc
    10501 ttgttacctg ataagatttt tggaaaaaat aaaaaaattt ggaaaatagt ttttgcaata
    10561 ttgacggcag tggcagcatt tatatttatg tactaagtta ttttaagaat gtagggaaat
    10621 aaaccctaca ttctttttag ttttttctgt tttctaaatt ctatttatcc aagcgcttca
    10681 acatttcttg cttcttcgct tcaagttctg cacgcttttc ttcgatttcg gcatgttttt
    10741 tctcgagttc agaacaactt gcaccattgc taaattcttt tcgccatcag gagatagggt
    10801 gagtcgacat gtctattact cacccaaagc agtcctacaa agcaggaatt ttctgttact
    10861 tttttggaaa tagtaacgtt tatacagctt tgacacttcg tatcaaagcg ccaaacacac
    10921 tccgagggat ttacagaaag cagaaaagga atgatctggt ataagatcat tccttttctc
    10981 tctttttctt taagtaatta tatacaatgt acgacgaagt cgtcattgca atgctgatcc
    11041 accacctaaa gggaacttta aacaacattg ataagataaa gaatataaac aacgaaaata
    11101 cgttataccc aattaatttt attgtatatc tcatgattaa aagttaatcc ttccgttgtt
    11161 aggaatggca tcatttttat cccataattg tgttaaataa gtccccggtg ataataaatt
    11221 catagcggat tctaaagcaa catcatttac aaaccaacta cctagatatc tagaaattgc
    11281 tgaacgaata gcactttttg ctgcatgttt tccttttact ttaattagat ttgcaaggcc
    11341 tgcagtagtt cctcctaatg ctaaagctat tgcagtatct aatagagcac ccatttgatt
    11401 aactgtaata ccttgccaag ctgctctaaa tggagagtat gtaggtggga ttgtataatc
    11461 gccttgtaat tgtcggttaa ttacttcttt gatccattgt tgtgagacgt ctggatgaaa
    11521 agattggatt tcgtttgcaa gtgtattgat ttgttcttct gttagagaag tgacaggttg
    11581 aagttccata tttgtttcaa tttgtgatac ttgttcagaa gcgtatacag ctgaaacact
    11641 tggaatcgct gatacaatta acacaattga cgtcaaaaaa accgaaataa atttcattaa
    11701 tttgttcatg agcttttctc ctttttattt gtatttgctt acattttatt atatactgtt
    11761 attatagtca agaaaaatat gctattatgt taaaaaaata tttttcaaaa tataaatgga
    11821 cggatttatt ttggattctt tttgtaattg gggcatgcct cttgacgggt aatagtagtc
    11881 ttttccccct tacccatcaa gaattctctt ttcgtggtag cgtttggggt ctggtactgg
    11941 ccttatatca cttattgttc attgataagt ttgtaatttc gaatcgaaaa taaaaattag
    12001 aactatgatt gactggctac ttttaatatt gattttggag gaagattttg tctctattat
    12061 ttattatttt aaatttatct attttgtaca agatttattc tttgagacgg gagaagtcga
    12121 aatacttgat ttatacggcc tatatcatat ttggggtaaa tgtagtatat ggtattcaat
    12181 ggttattaaa agaactgatt tcaactattt ccacttaata tgtatgaaaa ctataacaaa
    12241 acgcataaga ttaaggtttt taagcacctg ttcttatacg tttttgtaat attgaagatt
    12301 ttcggtaagt tttctacttt tgcgaagtct agtttagaat gctttcccaa ccaaaatctc
    12361 tgcttcgatg gtaatctctg tcagttggct ccagtcaatc ttgctctggt caacgtgaaa
    12421 gaggagagga gtcatactga gtagggcttg gagttgttct gctgtgatag tcttagtcag
    12481 agaggcagtt tgactagata ggatggtaaa gtgttcctgg aaatgctcct tgatatcttg
    12541 gttagaatac tccttgtttg tcagctggtc ctgtactctt tgacggattt ctttgaggtg
    12601 attttcagtt gggataacct ttatcaagat accgtctttg gataaaacgc gacgaaattc
    12661 tccatagttg gcaggtgaga agatatcaag cagaatatcc atgttagcgt cttttatagg
    12721 aagtcgtgcc aagtcgccaa cgaaccaatt gactgcccag ttgggttcac ttttagcagc
    12781 gatttggact gaatctttgg agatgtcaaa ggcatagaaa gttttttcag agtgactttc
    12841 ttgtagtttg cgagaataga atccttcacc acaaccgata tccaaaattg ttgtggtagt
    12901 ttttgagctt gcaagcaagt cagatacagc atctaagata gcttggtaaa agccggcttc
    12961 taggatttgt tgacggtttt gaaaattttc cttgtcatag ttagcagatt gcttgatttg
    13021 aggtgctaga ttgacatagc caaatttcgc caagtcaaaa gaatgacggt tgcagcactt
    13081 gaaattagtc tctaacagag tcagattttc ttgacagata ggacaggcaa aggcagtcgc
    13141 agaagcaaaa cgctgaagtt tgggcttgag atttgtattc atagtttaag tgtatcaaaa
    13201 gaggcaaatg aaagcaactt taggaataag tagatgggag attcagtaga aataaaacta
    13261 attctccaat ttatagaatg aaattgcttt tatatctaaa ttgctatata ataatgataa
    13321 ggaggaaata agtatgttaa aagaagtatt aaccgttgca aaagttgcga aaaaatcttc
    13381 attatttttg ggtggtgtcg catttggtac ccttggtttg aaaatcttag caagtaagga
    13441 agctaaaaaa ggttattcta aagctttggc taaggcttac aagttgaaag acgagctaga
    13501 tgcatctgtt tctgttgtga agcaacatgg agacgatgtc ttgcaagatg ccaaatattt
    13561 gtacgagcaa gagaaaaaag aagagcaatt agatagcctt ataggtgaat aatatgtctt
    13621 ttaaagtgct acatagagga taccaacata tccgactatc atcttctttt tcacttacct
    13681 tggatattca agactatctt cgttccttgg cgagagatga aaaggggatt gagtctatcc
    13741 agttttacat ggatcaacag cactttactc tacgcataaa agaaggcttt tctgtattag
    13801 ataatgcaga agccttttta aaaagaattg ataaagggaa agtttctgag ttgatgactc
    13861 ttcccattcg tagagaagag agtgcttatt ctattgtttc aggtgcagcg gttaagcgtg
    13921 tactttttcg tagttttgtg ccgtatccta ttcgctatat atggacttgt tatcaggctt
    13981 tgggttatat tagagaagcc tatcaaacac tagcgcgtaa ggaactaacg atggaagtct
    14041 tggactgttc ggctatttta ttgtccttgt ttatgaacca atccaagaca gctagcaata
    14101 tcatgtttat gcttgatttg gggaatcatt tagatcagtg gtccttgaaa aaaactgcaa
    14161 cagatttaga acagagtctt cttgcaaaag agagcgatgt attcctagta cagggcgata
    14221 cggttgttag tataaagagt tccgatgttc aaataggaga tgtcttgatc ttatctcaag
    14281 gaaatgaaat tctgtttgat gggcaagtag tttcaggttt aggtatggtc aacgaaagtt
    14341 ccttgacagg agagagtttt ccagttgaaa aaagagagtc tgatttggtt tgtgcaaata
    14401 cagtattaga aactggagag ttacgcattc gtgtaacaga taatcagatg aacagccgta
    14461 ttttacagct gattgagttg atgaagaaat ctgaagaaaa caagaaaacg aaacaacgct
    14521 atttcatcaa gatggcggat aaagtcgtca aatataattt cttgggggct gggctgactt
    14581 acctattgac aggttctttt tctaaggcta tttctttcct attggtcgat ttctcctgcg
    14641 ctttgaaaat ctctactcct gtagcttatt tgacagttat caaggagggg ttgaaccgtg
    14701 aaatggtgat taaggatgga gatgttctgg agaaatatct ggaagttgat actttcttgt
    14761 ttgataagac aggaacaatc acaactagtt atcctatagt tgaaaaggtg ttaccttttg
    14821 gagactatag tgaggaagat attctcagaa tcagtgcctg tcttgaggaa cacatttatc
    14881 atcctattgc taatgccatc gtcaagcaag ctgagataga gggaattgaa catgaggaaa
    14941 tgcatgggaa actccaatat atcgcaagca aggggatcaa atctcatata gatggccaac
    15001 cagttcttat tgggaattat gtcttgatgc aggatgagca gattcatatc agttcagaac
    15061 aaaatgcttt aattgaagag tacaagagtc actacaatct cttattcttg gcttatcaaa
    15121 atgaattgat tggaatgttc tgcattcata ctcctttgag aaaagaagca aaaacagcct
    15181 tggataaact taaggcacag gggaaaaaat tgattctggc aacaggagac accttgatta
    15241 ggacagagga attagtcaaa gatttgccct ttgatcaggt ctatacagac ttgaaacctg
    15301 atgggaaatt tgagttagta gagaaactgc agaaagcagg tcacactatt ttgatggttg
    15361 gagatggctt gaatgactca gcggctttaa ctctatcaga tatcggtgtg gtgatgaatg
    15421 agagtgcaga tatttctaag cagatgagtg atatcttatt gttagataat cgtttggatt
    15481 tcttccaaga gttggattcg ttatcatcat ctttgcaaac actcatcaag aaaaatattc
    15541 aggataccgt tgtcgtaaat agtagtttga ttggctttgg cttatttaat tggttcagtc
    15601 cttcaaatct ctctatctta cataatctaa caaccttgcg cattgtcctg cgtagcctgt
    15661 ctattaaaaa tagatagatg agagttatta acagcaaaaa ggagttacct ttctcgaggt
    15721 taactccttt gtttatagat aaatgttgaa tagtttagta agtcaataca aagtattttt
    15781 tcttcccacg acggataaca gtcagttcat tttctaactt atcagcgtca ctcaagacat
    15841 agtcaaggtc ttggatgcgg tcgccgttta cgtagatggc tccgttttgg acgtcttcac
    15901 gggcttggcg ttttgagtta actataccag atgagacgag cagttccacg atattgttgt
    15961 tttcgtctgc ctgtacttgg tagtttggca caccacgaag tccttgtttg agctctttga
    16021 cagaaaggtt tttgatgttt cctgcaaaga gttgctcagt gatgttaagt gcttctttgt
    16081 aggcttcttc tccgtgaaca agtgtaacaa cttcacgagc caagactttt tgagccaagc
    16141 gttcgtgtgg cgctgcttca aattgtttac gaatatcttc aatctcatca agtgacaaga
    16201 aagtaaagat tttcaagaag cgaacagcgt cagcgtccat cacgttcatc cagaattggt
    16261 acatttcgta tggagaagtc ttttcgggat tgagccagac ggcatttcct tctgatttac
    16321 caaatttctt accagttgca tctgtgatta gtggaacagt gataacgtga ccagtcttgt
    16381 ccgccttacg acgaagcaat tcggtaccag ctgtcatatt tccccactgg tcagaaccac
    16441 cgatttgaag agtgacatta tggtcttggt taaggacgaa gaagtcgtac ccttgcatga
    16501 tttggtaagc gaactcagtg taagaaattc ctgtttcgat ccgtttttta acagattcct
    16561 tactcatcat gtagttgacc gtgaagtatt ttccaatatc acggaggaag tcaatgaagc
    16621 tgatgctgcc aaaccagtcg tagttgttga ccatgacagc cttgttttcg ccattttcaa
    16681 agtcaagaaa acgagaaagt tgtccttgga tagacttgac ccagccatct actgtgtctt
    16741 ttgtttggag actacgttca gcatctttga aggacggatc tccgatgaga cctgtagcac
    16801 cgccaacgag cgcataaggt ttgtgacctg ctagttgcaa gcgacgactt gtcaagattg
    16861 cgacaaggtg gcctaggtga aggctgtcag cagttggatc gtagccagta tagtaagaaa
    16921 cttgaccttc ttctagggct ttacgcaaag cttcttcatc agtcgtttga aatatcaaac
    16981 cacgctcttt tagctcatca aaaatgtgca tgtgtctttt ctccttttta aaattattgt
    17041 ttctacctat tgtatcacaa acttgggcaa tagcctagca gaatagggaa gaaagtggct
    17101 attttattga aaatttccct tttgtggtat aatagataaa gtgaggaaat ccatgcaaaa
    17161 tcaattaaat gaattaaaac gaaaaatgct ggaatttttc cagcaaaaac aaaaaaataa
    17221 aaaatcagct agacctggca agaaaggttc aagtaccaaa aaatctaaaa ccttagataa
    17281 gtcagccatt ttcccagcta ttttactgag tataaaagcc ttatttaact tactctttgt
    17341 actctgtttt ctaggaggaa tgttgggagt tgggattgct ttggggtacg gagtggcctt
    17401 atttgacaag gttcgggtgc ctcagacaga agaattggtg aatcaggtca aggacatctc
    17461 ttctatttca gagattacct attcggacgg gacggtgatt gcttccatag agagtgattt
    17521 gttgcgcact tctatctcat ctgagcaaat ttcggaaaat ctgaagaagg ctatcattgc
    17581 gacagaagat gaacacttta aagaacataa gggtgtagta cccaaggcgg tgattcgtgc
    17641 gaccttgggg aaatttgtag gtttgggttc ctctagtggg ggttcaacct tgacccagca
    17701 actaattaaa cagcaggtgg ttggggatgc gccgaccttg gctcgtaagg cggcagagat
    17761 tgtggatgct cttgccttgg aacgcgccat gaataaagat gagattttaa cgacctatct
    17821 caatgtggct ccctttggcc gaaataataa gggacagaat attgcagggg ctcggcaagc
    17881 agctgaggga attttcggtg tagatgccag tcagttgact gttcctcaag cagcattttt
    17941 agcaggactt ccacagagtc ccattactta ctctccttat gaaaatactg gggagttgaa
    18001 gagtgatgaa gacctagaaa ttggcttaag acgggctaag gcagttcttt acagtatgta
    18061 tcgtacaggt gcattaagca aagacgagta ttctcagtac aaggattatg accttaaaca
    18121 ggacttttta ccatcgggca cggttacagg aatttcacga gactatttat actttacaac
    18181 tttggcagaa gctcaagaac gtatgtatga ctatctagct cagagagaca atgtctccgc
    18241 taaggagttg aaaaatgagg caactcagaa gttttatcga gatttggcag ccaaggaaat
    18301 tgaaaatggt ggttataaga ttactactac catagatcag aaaattcatt ctgccatgca
    18361 aagtgcggtt gctgattatg gctatctttt agacgatgga acaggtcgtg tagaagtagg
    18421 gaatgtcttg atggacaacc aaacaggtgc tattctaggc tttgtaggtg gtcgtaatta
    18481 tcaagaaaat caaaataatc atgcctttga taccaaacgt tcgccagctt ctactaccaa
    18541 gcccttgctg gcctacggta ttgctattga ccagggcttg atgggaagtg aaacgattct
    18601 atctaactat ccaacaaact ttgctaatgg caatccgatt atgtatgcta atagcaaggg
    18661 aacaggaatg atgaccttgg gagaagctct gaactattca tggaatatcc ctgcttactg
    18721 gacctatcgt atgctccgtg aaaagggtgt tgatgtcaag ggttatatgg aaaagatggg
    18781 ttacgagatt cctgagtacg gtattgagag cttgccaatg ggtggtggta ttgaagtcac
    18841 agttgcccag cataccaatg gctatcagac cttagctaat aatggagttt atcatcagaa
    18901 gcatgtgatt tcaaagattg aagcagcaga tggtagagtg gtgtatgagt atcaggataa
    18961 accggttcaa gtctattcaa aagctactgc gacgattatg cagggattgc tacgagaagt
    19021 tctatcttct cgtgtgacaa caaccttcaa gtctaacctg acttctttaa atcctactct
    19081 ggctactgca gattggattg ggaagactgg tacaaccaac caagacgaaa atatgtggct
    19141 catgctttcg acacctagat taaccctagg tggctggatt gggcatgatg ataatcattc
    19201 attgtcacgt agagcaggtt attctaataa ctctaattac atggctcatc tggtaaatgc
    19261 gattcagcaa gcttccccaa gcatttgggg gaacgagcgc tttgctttag atcctagtgt
    19321 agtgaaatcg gaagtcttga aatcaacagg tcaaaaacca gggaaggttt ctgttgaagg
    19381 aaaagaagta gaggtcacag gttcgactgt taccagctat tgggctaata agtcaggagc
    19441 gccagcgaca agttatcgct ttgctattgg cggaagtgat gcggattatc agaatgcttg
    19501 gtctagtatt gtggggagtc taccaactcc atccagctcc agcagttcaa gtagtagttc
    19561 tagcgatagc agtaactcaa gtactacacg accttcttct tcaagggcga gacgataatt
    19621 ctctaaatga agtggccaat caatggattg ccactttttt cttttcgtgt tacaataagg
    19681 gtatgaatca gtatcagaaa aagattgtta acggaaaaat ttattcgctc ctatccggct
    19741 taatatgggg aatctgtgga attttaggag agtacttctt tactcattat caggtgtctt
    19801 cgggctggat tacctctatg cgtttgacac tggcagggag tcttgtactc atttggtctg
    19861 caatacaatt aaaatcgcaa gtgctagata tttggcgaga caagaaaaat tacctgccct
    19921 ttttagccta tgctattttg gggatttttt cagttcagta ttttttctat ctctgtgtag
    19981 aatactcaaa tgctacgaca gcaactattt tacagtttat tagccctgtc tttatcctct
    20041 tttacaatcg cttggtttat caaaaacgag cgtcaaaaag cgctgttttc tatgttttgg
    20101 ttgccatgct gggtgtttgc ttgatggcga caaagggaga cctctctcag ttatccatga
    20161 cgccgctagc tcttataaca ggtttgctga gtgccatggg tgttatgttt aatgttatct
    20221 tgccccaacc ttttgctaag cgttatggtt ttgttcctac ggttgggtgg gggatgattt
    20281 tggcaggttt gtttagcaat gtcctctcgc cggtttatca gctttccttt actcttgata
    20341 tttggagtat cttgatttgc ctcattatcg ctttctttgg aacggctttt gcttttttca
    20401 tttccatgaa ggctgtgtcc ttggtttctc ctttggtggt tgccgttatc agtgccagtg
    20461 aacctctctc ttctgctctc ttgagtgttt tgttcttagg attagtagtg gattggtccc
    20521 tccttctagc tatagccttg attattttac ccatgatatt tttgtctata gaagaagcga
    20581 aagaaagtag ataaaaagtc ttttcttaat tctaaaagtg tgctatactg gaatagtcaa
    20641 taaaacacgg ggagatagtt gtgaagagtg tttttaggtt gtatcggtag gggcttgctt
    20701 ttaccgacag cacgttttat ctcacatccc taaaaaatca tacctaaaaa cagacaaaaa
    20761 ggtttcaaat ttgaggcctt ttttggtaga ataggtatca ttataacgaa ccaggaggca
    20821 cctatgactg ctacaaaaat gaacgctcaa gaaattatcc aatttatcgc caatgctgaa
    20881 aagaaaacca gtgtcaaagt aacctttgag gggcaactcg caactgctgt gcctagctct
    20941 gttgtcaaac taggaaatgt cctattcgga gactggaagg acgtggctcc gcttcttgaa
    21001 ggtttggtag aaaatcaaga ttatgttgtc gagcaagatg ctcgtaattc tgcagttcct
    21061 ttgctagata agcgtgctat caacgctcgt atcgagccag gtgctattat ccgtgaccag
    21121 gtggaaattg gtgacaatgc tgttatcatg atgggagctg ttatcaatat cggtgctgaa
    21181 atcggtgctg gaaccatgat tgacatgggt gccatccttg gtggccgtgc cattgttgga
    21241 aaaaatagcc acgttggtgc aggtgcagtt ttggcaggtg tgattgagcc agctagtgct
    21301 gaaccagtcc gtgtcggaga caatgttctc atcggggcta atgcagtggt tatcgaagga
    21361 gtccaaatcg gtagtggttc agttgtcgca gcaggagcta ttgttaccca agatgtccca
    21421 gaaaacgtgg tagtagcagg tgttccagct cgtattatca aagaaattga tgcccaaact
    21481 caacaaaaaa cagcgctaga ggatgcgctt cgtaccttgt aattgtaaaa gtaaaaaaga
    21541 ggcggaaccc tttttccagc ctctttctgc tatatcggag gacagataga tgttagattt
    21601 gattcagact agacgagatt tacaccagat tccagagatt ggcttggagg agttcaagac
    21661 tcaggcttat ttgctggatg tgattgagaa attgactacg ggcaaggatt ttgttcaaat
    21721 tcgtacttgg cggacaggga ttttggtcta cctgcaggga agtcagccgg agcgaaccat
    21781 tggttggcgg acagatattg atggcctgcc tatcgtcgaa caaacaggtc taccttttgc
    21841 ttctcaacac caaggtcgca tgcatgcctg tggtcatgat tttcatatga ccattgcctt
    21901 aggctgtctt gagcgcgccc ttgaggagca acccaagaat aatctgctct ttctatttca
    21961 gcctgctgaa gaaaatgaag ctggtggtat gctcatgtat gaggacgatg cttttggaga
    22021 ttggttgcca gatcaattct atggtctcca tgttcgtcca gatttgaaag tcggccagat
    22081 tgcgactaat actcatacac tctttgcagg aacttgcgag gtgaagatcc gtttcaaagg
    22141 caaaggtggc cacgcagctt ttcctcatga agccaatgac gccttggtgg cggctagtta
    22201 ctttgtgacc caagtgcagt cagttgttag ccgcaatgtc aacccaatcg agggagcagt
    22261 ggtgaccttc ggcgtttttc aagctggaac caccaacaat gtcatcacag acacagcttt
    22321 tttacatgga actattcgtg ccttgacaca ggacatgagt ctcttggtgc aaaagagggt
    22381 aaaaacagtt gcagaagggg ttgcagctgc ctttgatatg gaagtcgaag tggaactcaa
    22441 acaaggtgga tacctacctg ttgagaacaa tccagccttg gcgcgtgaac tgatggactt
    22501 ctttgacgag aaagacggaa tcgagttgat tgatatcgaa cctgctatga caggcgagga
    22561 ctttggttat ctcctttcaa aggttgatgg cgtgatgttt tggctaggta tcgatagtcc
    22621 ctacgctctt catcaccctc aaatgagtcc taaggaagaa gtcttagcta ttggggtggc
    22681 tgcggtgtct agtttcctga aaaagaaggc agcagaatag agggcttgtc tatgaaatcg
    22741 gaattacgca agcaagtctt gcatgaaatg aaggctatat ctcaagagca aaaacaggct
    22801 atagaccaag ctttaaccga gcggctttta caccatccct tctaccaaga agccaaggtc
    22861 atcgcaacct acctctcttt ttctcatgag tttcaaacgc gggaactgat tgagcaggcg
    22921 ctgaaggacg gcaagaaggt tttaataccc aaaacttatc ccaaggggcg catggagttt
    22981 gtggcctatg atccgcaaca gttggtaaaa acttcctttg ccttactgga gccacaggga
    23041 gatgtggaag tggtggatgc atctcagatt gatttgattc atgttcctgg tctggctttt
    23101 acgacgaaag gatatcggat aggatacggt ggaggctatt atgaccgcta tctggaacat
    23161 ttttctggtc gtactttgag tacgatatat ccttgtcaaa ttcaggactt tatacctgaa
    23221 aaccatgata ttcctgttca ggaggtatta attgatgaag gaaatctttg atagacgtta
    23281 ccctgtgacg agtttcttcc tcttagtgac ggccttggta tttttactaa tgttggtcac
    23341 tgcaggcgga aactttgaca gggcagatac attatttcga tttggagcca tgtatgggcc
    23401 agctattcgc ctctttcccg agcaggtttg gcgtctcttg tctgccattt ttgttcatat
    23461 tgggtgggaa catttcattg ttaatatgct ttcactttat tatcttggaa ggcaggtaga
    23521 ggagattttc ggttctaagc agtttttctt tctctatctt ttatcaggaa tgatgggcaa
    23581 tctctttgtt tttgtattta gtcctaaatc cttagcagca ggcgcctcta cctctcttta
    23641 tgggctattt gccgcgatta ttgttcttcg ctatgcaact cgcaatcctt atatccaaca
    23701 gctagggcaa tcctatctga cactttttgt ggttaacatt attggaagtg ttctgattcc
    23761 aggaatcagc ctagcaggcc atatcggtgg tgcagttggt ggcgcatttc tagcagttat
    23821 ctttccagtt agaggagaaa aacggatgta taacaccagc cagagattag gagcggtagt
    23881 cttgttcgta ggactcgcca ttttgctttt ctacaaggga atgggaatgt gacgaagttg
    23941 aaagaaaatt tgtgtaatga aaaaagataa ggcatttttt gaaccttatc tttttatttt
    24001 attccttctc agtcaattct tttccaagtt ggatgaggta attcttcaaa tcatctttga
    24061 cttgtggatg tttgagggcg tagtcaatag atgttttcat aaagccaaac ttatccccaa
    24121 cgtcgtaacg agctcctgta aattcacggg caaaaacacg ctgtgtttta ttaagagtat
    24181 cgattgcatc agtaagttgg atttcatttc cagcaccagg agcttggttt tcgaggattt
    24241 ggaaaatttc aggcgtgagg aggtagcgtc cgataatagc aaggtcgcta ggagcgtcct
    24301 ctggagctgg tttttcaaca aaggtttcaa cactgtaaag accatctttt ccttcgcctt
    24361 gcggagcaat aaccccgtaa gcagatactt cgtcatgagg gactggcatg acagcgatag
    24421 tagacgcgtg ggtacgcttg tagtcatcca tgagttgttt ggtaagtgga acagcctttt
    24481 cgtctgtgat atccatcaag tcatcaccaa gcataacgac aaaaggttca tttccgacga
    24541 aagccttggc ttgcaaaaca gcatctccga gaccgcgtgg atgagtttgg cggataaaat
    24601 gcagacgcat gccagttgtt tcatcaacta gcttcaaaag atctgttttc cctttttctt
    24661 tgaggttata ttccaattcg aagtttgaat cgaagtggtc ctcaatagaa cgttttgatt
    24721 taccagtgac aactagaata tcttcaatac ctgatttgag agcctcttcc acgataaact
    24781 ggatagttgg tttgtctacg attggcaaca tttctttggc aagggccttg gttgctggta
    24841 aaaatcgagt tcctagtcca gcagcaggga taactgcctt tctaactttt gatgtcataa
    24901 aaatcctttc tatagagggt taagaccact cattttctgc tttaaattca ttgttcatga
    24961 tgtcataaat ggcatctttg atattggttc cgtgataaat aacttggtaa atagcctgtg
    25021 taatgggcat atagactcca agttcttggg ctagttcata ggctgctcga gtcgttgaaa
    25081 ttccttcgat taccatgccc atattagctt ctatatcagc tagggattct cctcgtccga
    25141 gagcatctcc agctctccag ttacgagagt ggatggaagt tcccgttacg atcaaatctc
    25201 ccacaccaga taagccgcta taggtcaatg gactggcccc gagtgctacc cctaggcggg
    25261 tgatttctgc taaacctcga gcgatgatgg ctgccttagc attatcacca aatccaagac
    25321 catgtaaagc tccagcaccg acagcaataa tatttttaag agcaccagca gtttcaaccc
    25381 cgataacatc cgtattggta taaagtcgga agtagtgatt actaaatagc tcctgaacgt
    25441 attgagctgt ttgtaaatct ttagaagcag cagttattaa agttaggtca cgcacaatgg
    25501 tctcttctgc atgactaggc cctgaaacaa cgacgatatc actacggaga tgttcaggaa
    25561 tttcttcttc aagaatggtt gataatcgtt tatggctatc aggttctaat ccctttgatg
    25621 cgtgcatgat gataacctta tggtccaagg tttgtgcaac ttgctgggca acaagtcgtg
    25681 tcacttttgt tgggacaaca aacaaaatcg catccacatt tttcaatgtt tctgctaagt
    25741 cggtgtaggc aatgatattt tcgtctagaa cgacatcttt aaagtagtgc ttattagtat
    25801 ggtgtgtatt aatttcattg atttgctcgg gaagatttcc ccaaatacgt acctcgtgtc
    25861 cattgtcatt taagacttgt gaaagggcgg ttccccaaga accaggcccc aagacggcga
    25921 cggtttgttt ttccatgatt tcctccttga tagatttctt tctcttattc tatcatattc
    25981 taggggattt tgcacttgca ttactggggt atggtggaaa aatacacaaa gaccgagatg
    26041 aagggataaa ctcttagtct ttagttaaag tgagaagaaa tctgatagat agtttgattc
    26101 agtatatgct tataatagag gtaaacaact caggaagttc ttgtaggttg cgagagtttg
    26161 gcgaaaaaat taaaagatta cgtttggcta aaaaaatcag tcgttcagaa ttttgtggtg
    26221 atgagtctga attaagtatc cgtcaattaa ttagaattga aaatggagaa tccagaccaa
    26281 cactaacaaa gttaaaatat attgctgaac gtttggaggt tgaagattac aagttgatgc
    26341 caagttatat agagttggat aaggaatacc tagaattgaa gtatttcttg atgaggactc
    26401 ctacatacga agatgaaact atcgcccaaa agaaagagag tgtttttgat aagatttttg
    26461 aagagtatta tgataggcta cctgaggaag aaagatttat catcccaaat tattcatatc
    26521 tagcactagc gaactacaca gttcaaaaat taccagaaaa gctagttgaa atactgtcct
    26581 tctggtgatt ttgcttaatt tctgatgttc gagacatgat tgaggagatt tgtcttgatt
    26641 ttttcctaaa aaagggcaga ctcctccctt ggtttgatgc tcgattttta aaataaggtg
    26701 acttattctg ttaggcagtt ttcccctgcc ctctagctct atatggaaca gggagtatca
    26761 gatttatctg gcagattgta tcaaataagg cttgaaactg ttttgaatag gcgtatagac
    26821 ttgagaattt gagaatatgt cgtctagcag tagagacata ttttccggca atatgaagga
    26881 agagacgtcg aaaacgcttg atagtcaagg cctttacttc atcaccagct agctgcttta
    26941 aaaagaggta gagattataa gccagacagc ccatcatcat acgtacttca ttcttaatca
    27001 tggtcgaact atctgtctta tccccaaaga atcctgcttt cctttctttg ataaagtttt
    27061 cagcattccc tcgttcacga tagaattgaa acagctcctc actatctaca ctgcttaaat
    27121 tggtcaaatg aactttttta caaccataaa aaagagcact taatcgtact cttctctttt
    27181 aaggattagt tgaattaatt caaatccact agttctcctg tttctaggta gactaggcgt
    27241 tcacaaatgt tagcaatgta atcagcgaag cgttccagat gccctatgat ataaaggtat
    27301 tgagttccat tgggaattga ggtttcttgg tctttcataa gtccaatgat ttcctttgat
    27361 aaggcataat aatattggtc aatctgttca tctttttgag caatactaat agcttttgag
    27421 gcttggtgca aaggaaaggc aaccaataaa tcggctagca tgctgaggga taatttaccc
    27481 atttggtgta actgttcttc gtcaggggct agttgatttt cttttagttg caaaacagct
    27541 ttggcaatgc ctgccatatg gtctcccata cgttcaaggt ctgaacaaga agacatgatg
    27601 ctaatcacaa atcgaaggtc agacacttgt ggctgctgca aggccaacaa acgggcacag
    27661 gtcaattcga tagcgctttg accttggttg atagcatgat ccttattgat aattagctct
    27721 gccatctcct tgtctttgga ggctaaggcc agtaaggctt ttgaagctgt ttcaaggaca
    27781 agttgcccta gtcctaaaaa ggattgttct aattcatgca attctaagtc aaattgattt
    27841 ctcataggtt tttccttcct tatccgaacc gtcctgaaat atagtcttct gtgcgctgat
    27901 cttttggatt ggtaaacacg tcaacggtat ctccaaattc gcaaatttct cctgttaaga
    27961 aaaaagcagt tttatctgaa atacgtgaag cttgttgcat gttatgggta acaatgataa
    28021 tcgtataatc cttttttagt tgctgaatga ggtcttcaat ttttaaagtg gagatagggt
    28081 ctaaggctga agtcggctca tccattaaca gaatatcagg ttctactgct aaagctcgcg
    28141 caatgcaaag gcgttgctgc tgaccgccag ataaggacat agcactcttt ttaagatcat
    28201 ctttgacttc ttcccaaatg gctgcccctt ttaaagattt ctccactaag gcatctaatt
    28261 gttttttgtc tcgaatacca tgtgtccttg ggccataagc cacgttatca tagatagaca
    28321 tggcaaaggg attaggctgt tgaaaaacca tccctacacg cttacgtagc tgattaaggt
    28381 tgaatttgct actataaata tcttgctcat ctaagaggac ttggccttca atatggcaag
    28441 aaggaaccaa atcgttcatc cggttaaggg tttttagaaa agttgatttg ccacaaccag
    28501 atgggcctat caaggcagta atctgtcttt ctggtaattg aatcgaaata ttttttaagg
    28561 cttgaaaatc cccgtaaaat aagtctaggt gtctgactga aaatgttccc atactaggaa
    28621 gctcctttca caagttttcg agataataag cttgatagag tatttatcat taaaacagta
    28681 ataatcaaaa tcacaccggt agcataggct tcattgacat gtagcccctc acttgacagc
    28741 atatacatat gcagggctag agaacgacct gaagacatga gactacttgg cgtattggta
    28801 gaggtaccta atgtatacat gagggcagct gtctcaccaa cgatacggcc aatagctagt
    28861 atcactccag ctaaaatacc tggcatggca actggtagaa caattctaaa aacagtccgt
    28921 aacttacctg ccccaagtcc ataacttgct tgacgcatga tatcactaac agataaaagg
    28981 gcttcttctg ttgagcgaat aatgactggc aacaccatga tgactgaggt taagattcct
    29041 gataacagag agtattgaaa acctaagaag actacaaaga agagcatgcc aaacagacca
    29101 aaaacaatgg aaggaatccc agacaaggta tctgaggcca atcgcatgat tttaacacaa
    29161 agggaatctt tttttgtata ttccacaaga taaaaaccag caaaaatccc tatgggcaag
    29221 gctaaaagaa gagcaccaaa gaccagaata acggtggaaa taatcgctgg cataagggaa
    29281 atgttctcag aagtataagt ccaagaaaag agggatagac ttagatgagg taagcctttg
    29341 atgaggataa aaccaatgat taaaaagaga gagccaaagg ttaaagctga aaaacaataa
    29401 acgagaagtt ttagcaggta tttactcata agatgatttt cctttcaagt aggcaaagta
    29461 ggcattaatc aagagaataa ggaaaaagag aactgctgag gttgcaataa gggcttccct
    29521 atgctgacct gatgcgtaag ccatttccag aacaatattg gttgttaagg ttctggttcc
    29581 tgaaaagagt ccacttggaa taatcggctg gttgcctgcc accaaaataa ctgccatggt
    29641 ttcacctact gcgcgaccga ttcctaaaat aactgctgat aaaataccag atctcgcagc
    29701 tggcaagatg acactaaaaa tactccgttc atgactagct cctagagcca agctaccaga
    29761 ataatacgtt ttgggaactg ttcggatagc agattctgac aaactgataa tggttggcaa
    29821 aatcattatt cctaatagta acgaagcggt taggacactc atgccatttc ctaaaaagct
    29881 tctaatccaa ggcaccaata attgtaggcc gaaaaaacca taaacaatag atggaatggc
    29941 cgccatcaag ttgatagctg attttaagaa gccatagacg ggctttggac aataataaac
    30001 cataaacacc gatgtcaaga tgcctgttgg caccccaatc acaatcgctc ctaaggtaat
    30061 taataaggaa ccaacgatca ttggtaaaat accatagctt gccggaatgt tcgttggcga
    30121 ccaatcactg cctaataaaa aacgggcaaa gccgtagtta gccatgaaag gtaagccatt
    30181 actaaaaata aagaaacaga ttagcaaaat agctacaaca gctactgttg cactcatgaa
    30241 aaaaattgcc ctaaaaactg cttctttgaa ggcttgtttt atcacatctt gtcctttcta
    30301 gtgaagaaag taagggagat acgacacctc cctacttgcc ttctttatct tattgtacga
    30361 tgaaacgtct gcatctcttt agagatttat ggagcaaaca ttttatttaa tcttgtccca
    30421 ggtggttaat ttgccactaa aaacgtctgc aagttcagcc atactgactt ggcttgcctt
    30481 attgtcatta ttgaccacaa cagcaatacc gtctaaagca atagcatcat gggtgagact
    30541 cttaccttct tcaggagtta attccctaga aaccatacca atatcagcgg ttttctcctt
    30601 aacagcggta atacctgctg aagacccatt agaggtaata tcaatcgtaa cttctggatt
    30661 ttctttttta taagcttctg ctaatttttc cattaaagaa gatactgaag tggaacctac
    30721 aacagacaac ttgcctgata agtgttggct tgtatattct gtggtttcag ttttagcttc
    30781 aataaattta ttatctgtga ccacttgttg accttgtttg gagtggataa agctgataaa
    30841 atcttgacct agcttggaaa gattagaaga ccaaacaatg ttgaagggac gttgaagagg
    30901 gtattcacca tctaaaactg tgtctcgact agccttgaca ccatcaatct ctaaagcctt
    30961 gacagatttc gttaaagatc ccaaggagat gtagccgata gcattagcat tcccttgaac
    31021 tgctgagaga acaccttctg tactattttg aatcacagct gttttggcag tgttgtcaat
    31081 ttttttatca ccgtcttttt tgagaatccc tgtgatttct gtgaaggcac cccgtgttcc
    31141 agagccattt tctcgtgaaa tcacctcaat cgttcctgaa gctgactgtt tggaagcagc
    31201 tgactgattg ccacaggcaa caagcccaaa tcctgataag ccaatggctg caagagtaag
    31261 catttttttg aatttcataa taatcacctt tatctctatg tatttttctt gtgtaggctt
    31321 actacattta tagtctaaca agtctttgta aaggtttatc cctgattcat gtaaagattg
    31381 tgtaaagaat caaaaaaagc cacttttgaa aaatggctgc tcctaaaaat agctttaaaa
    31441 attattagtc ctgtgcgaaa gattggttag gaagaaaaat cgtgaagcaa ctgcctctgc
    31501 caagctgact tgtcaccgtg acttggccac ctaataattg actgagttct ttgacaatgg
    31561 caaggccaag accagtgcca ccagtttgtc tgcttcgacc tttattaact cggtaaaaac
    31621 gttcaaaaat acgatcctgc tctaattgac taataccaat ccctgtatct gatacagaaa
    31681 tcttaatgcc ttcgttcacc ttttgggtct tgacctcaat ttttccccct tgttcagtgt
    31741 aacggatggc attggataaa agattgagta agatttggga aagtaattga ctatctgata
    31801 cgagggtgac atcatctggc acctgcacct ttagctgtaa atccttcttc ttgagctgag
    31861 gttgcaagct ttgagtcaaa tcctgtacaa attctgccaa agaaagggtc gtccattgta
    31921 taggcatttg ttgagcctta gataaggtaa gaagatgctc aacaatatgc tcaagacgca
    31981 agctttcttt gtaaataatg tctagaaagt catccttgag cgcttcttct tcagcagaca
    32041 tccccttaat ggtttcagca aagcccttaa tcgaagtaac tggtgtcctc aattcatggg
    32101 aggcatttga gacaaaggct aaatttaact tttcataagt tctaatcgtt gttaaatcat
    32161 atagcaagac gagcacagct tccacagatt gggtggggct aaaaacggga actgctgtca
    32221 cttctaaaat caagtcaccc tcatgaaacc cacttacttc ttgttttaac cttgtttttt
    32281 gatcaaaggc ttggtgaact aaatttcgaa tatccatccg tttgaggtca tcaagtgaac
    32341 ttatgtcgcc gtccacatcg ggaaaataat gaggcagaga gcgactggat aataacatct
    32401 gaccttgagc ggaaactaaa aacgtcccca tggttaggtg cgacagaaga acctccattg
    32461 tttcggctag gtccttgtat tgctgatcct gttgggagac tttggttttt aggccagaca
    32521 catactgagc caaagacttt aagtcttctt gccctttttc taaaaagtat tcactactgg
    32581 tcaagagagg ttggtgcaag gtctcaaaag caacttccca tttccaaagg caaaagagcc
    32641 agtagccacc ttgtcccaaa gaaagggcta gaagaaagag accgatgcct ttactgatcc
    32701 aagttaatgc catccctgca atcagaatga ggctaacact tagattgact agccaaaatt
    32761 gaaggtagcg tttcatctat aactccttga acttataacc ataaccccga atggttcgaa
    32821 taaattgagg ggctttagga ttgtcttcaa ttttttccct caacttacca atatgaacgt
    32881 ccaccaaacg tgtttcctgc ccaaagtcat acccccagat acgttccaaa agacgctctc
    32941 tagtcagtgt catgttggga tgtttcataa gatagagcaa gagttcaaat tcttttgggg
    33001 tcaaactcag taacttattc gccttgtaga cttcatgacg ctcagggtat actttcaagg
    33061 tcccaaatag ccaagaatcg tcagcgatat tatctgaatc atctccttct tgttctcctt
    33121 tagttcgcct gaggacagcc ttgacacgcg ccagcaattc tctagggcta aaaggcttgg
    33181 tcaggtagtc atcagcccct aattccaagg ccaaaacctt atcaaattca tcacttttcg
    33241 cagaaaccat cataattgga gttttgacgc ctttggctct cagccgctta caaacttcca
    33301 tgccatctaa ttgtggtaac atgatatcaa gcaagataaa atcaaagggt tctgtttctg
    33361 ccaaagctaa ggccttccgt ccatttgtta ccaattgagt agaaaagcct tccttactta
    33421 aatggtagtc aagcaatttc agaatgtgtt cttcatcatc cactaataag acttgttttg
    33481 tcatctatta tctcctattg gtaacattat aacacaatta tcagaaatcc taacattgct
    33541 aaatcagatt aaatttgcct atcaagacta gtatctggtc aaacgctcaa tcatctcctt
    33601 gtgctctgga taggtcgcca gtagatctac cctttcaaat aattcaaaat cctcaaattc
    33661 aaaaccagga gcaacaagac aagaaaccag agcatcatcc ttatcaactg ttgatcccca
    33721 aatagtgccc ttaggaacac agtagtgaag ttgttgccct ttggatatgt ccaggcctaa
    33781 agtgactgct tcgtagtgac catctgctgt aatcatgtga acagtaagtg gggatcctgc
    33841 atgaaaatac cagatttcat ctgctgtcaa tcggtgaaaa tgtgaaggat tcgtttcttc
    33901 taataagaaa taaatactgg tataaagcgc ccttccctta ccagcaaggt ttatagtgtc
    33961 tgaagctttt tttgtttgtc taaaatagcc accttcaaca tggggagcta actctagagt
    34021 tcttatcaag tcttctttat ccgtcggagc caatgggttg aagtaactct tgttcaaagt
    34081 ggttttacga tttcaagaac tcctctcagt tctgaggaca cggtaatgat tgatgcgacg
    34141 gaagtaaaaa tcaatcgccc taaaaaaaga attagcgaat gattctggta aaaagaaatt
    34201 tcacgctatg aaggctcaag cgattgtcac aagtcaaggg agaattgttt ctattgccat
    34261 gatatgaagt tgttcaaaat gagttgcaga aatatcggac aagctggtaa aatcttggct
    34321 gacagtgatt atcaagggct catgaagata tatcctcaag cacaaactcc acgtaaatcc
    34381 agcaaactca agccgctaac agctgaagat aaagcctgta accatgcgct atccaaggag
    34441 agaagcaagg ttgagaacat ctttgccaaa gtaaaaacgt ttaaaatgtt ttcaacaacc
    34501 tatcgaaatc atcgtaaacg cttcggatta cgaatgaatt tgattgctgg tattatcaat
    34561 catgaactag gattctagtt ttgcaggaag tctattattt ggttaggtga attagtgaag
    34621 tgtttaggca agtgtctctg gttacgacgt catggcctct aaatcgatta tatttagggg
    34681 tcatgactag tgaagcagtt agctagttcg catataagcg gctagcgtct aacaattagg
    34741 aactttagtt ccaataactt taagattacg acgttttagg acataaatcg atcatattta
    34801 tgtcctaaaa ctagtgaagc gcctagccaa agtccgaata ggatttggcg ttagttactt
    34861 agattgcttt gcaatcaagt aactttggcg atttacatct tctctggcgc ttctactcca
    34921 agcaagcgaa gggcttcttt gagaacgact gcggttgcgt agctgagggc tagacggctg
    34981 tcgcgttctg ggctttcatc caagatacgt gtatgtgcat agtatttgtt aaaggattga
    35041 gccaggctaa ttgcaaattt agcaatgata gaaggttcaa agttatctgc cgcacggttg
    35101 ataatacgtg ggaagtcttg aatgagttta atgatttccc agctttcagt atcattcaag
    35161 ctatagttgc cagctgtttc tggtttgaaa tcggctttgc gtaagataga ttggatacga
    35221 gcgtaggcat attgaacgta aggtccagtt tcaccctcga aggataccat agcttctagg
    35281 tcgaagtcgt atccatttgt acggtcagtt ttgaggtcat agaatttaat ggctccaacc
    35341 ccaacagcat gtgctacttg gtctttgttt tctagttcag gatttttagc ctcgatttgg
    35401 accttggcac ggctaacagc ctctgcaaca gtaggctcta gcaagatgac attcccttta
    35461 cgagtagaga gcttcttccc ttcttttgta accagaccaa aaggaacgtg ggtaatgtcg
    35521 tcactccaat cgtagcccat ctcttgcaag acagctttga gttgtttaaa gtgggcagat
    35581 tgctcttgac caacgacgta gatagattta gcaaattggt attcattttt acggtagagg
    35641 gctgcagcca agtcacgtgt gatatagaga gttgcaccat cagacttctt gatgagggct
    35701 ggatgttcaa ttccatattt ctcaagattc acaacttggg caccttctga ttcaagaagt
    35761 agtccttttt cagaaagaat gtctacaact gcatccatct tatcattgta gaaggcttct
    35821 ccgttatagc tgtcaaattc aaccttcaat tcattgtaaa ggcggttaaa ttccactaaa
    35881 ctttcatcgc ggaaccattg ccaaagagcg agagcttcct catctccatt ttcaagttta
    35941 cggaaccatt cgcgcgcttc ttcatccaag ctagggtcat tttcagcttc agcgttgatg
    36001 cggacataga gtttaaggag ttcatcgatt ggatgagctt ttacagcttc ttcgtcgccc
    36061 cattttttgt aggcaacaat caacatccca aattgtttac cccagtctcc caaatggttg
    36121 accttgaccg tttgataacc gattttttgg aaaatatgtg acaagctatc tccgataaca
    36181 gttgaacgca ggtggccaat agaaaatggt ttagcgatat tcggactaga catgtcgata
    36241 acaacatttt cttgtttgcc aatattttgg tcagcatagt gttctttttc agtggtaaca
    36301 gcttgcaata cttgagcaga aatggcagat ttatcaagga aaaagttaac gtaaggtcct
    36361 gttgcgacaa ctttttcaaa ggcttggctg ttcatttttt cagccagttc agccgcaatc
    36421 atttgtggtg ctttacgttc gacttttgca agagaaaaag cagggaaagc aatgtctccc
    36481 atttctgagt ttttaggggt ttccagtaac tttaaaatag cctcttggtc caggctatca
    36541 atgatgctag ataattcgct agcaatcaat tcttttgtat tcattaagag ctcctttttg
    36601 gacttttcta ctattttatc acaattttaa agaaagaaga aaaaattttt gaaatctcct
    36661 gtttttttgg tataatatgg ttataaatat agttataaat atgcacgcaa gaggatttta
    36721 tgagaaaaag agatcgtcat cagttaataa aaaaaatgat tactgaggag aaattaagta
    36781 cacaaaaaga aattcaagat cggttggagg cgcacaatgt ttgtgtgacg cagacaacct
    36841 tgtctcgtga tttgcgcgaa atcggcttga ccaaggtcaa gaaaaatgat atggtgtatt
    36901 atgtactagt aaatgagaca gaaaagattg atttggtgga atttttgtct catcatttag
    36961 aaggtgttgc aagagcagag tttaccttgg tgcttcatac caaattggga gaagcctctg
    37021 ttttggcaaa tattgtagat gtaaacaagg atgaatggat tttaggaaca gttgctggtg
    37081 ccaatacctt attggttatt tgtcgagatc agcacgttgc caaactcatg gaagatcgtt
    37141 tgctagattt gatgaaagat aagtaaggtc ttgggagttg ctctcaagac ttatttttga
    37201 aaaggagaga cagaaaatgg cgatagaaaa gttatcaccc ggcatgcaac agtatgtgga
    37261 tattaaaaag caatatccag atgctttttt gctctttcgg atgggtgatt tttatgaatt
    37321 attttatgag gatgcggtca atgctgcgca gattctggaa atttccttaa cgagtcgcaa
    37381 caagaatgcc gacaatccga tccctatggc gggtgttccc tatcattctg cccaacagta
    37441 tatcgatgtc ttgattgagc agggttataa ggtggctatc gcagagcaga tggaagatcc
    37501 taaacaagca gttggggttg ttaaacgaga ggttgttcag gtcattacgc cagggacagt
    37561 ggtcgatagc agtaagccgg acagtcagaa taattttttg gtttccatag accgcgaagg
    37621 caatcaattt ggcctagctt atatggattt ggtgacgggt gacttttatg tgacaggtct
    37681 tttggatttc acgctggttt gtggggaaat ccgtaacctc aaggctcgag aagtggtgtt
    37741 gggttatgac ttgtctgagg aagaagaaca aatcctcagc cgccagatga atctggtact
    37801 ctcttatgaa aaagaaagct ttgaagacct tcatttattg gatttgcgat tggcaacggt
    37861 ggagcaaacg gcatctagta agctgctcca gtatgttcat cggactcaga tgagggaatt
    37921 gaaccacctc aaacctgtta tccgctacga aattaaggat ttcttgcaga tggattatgc
    37981 gaccaaggct agtctggatt tggttgagaa tgctcgctca ggtaagaaac aaggcagtct
    38041 tttctggctt ttggatgaaa ccaaaacggc tatggggatg cgtctcttgc gttcttggat
    38101 tcatcgcccc ttgattgata aggaacgaat cgtccaacgt caagaagtag tgcaggtctt
    38161 tctcgaccat ttctttgagc gtagtgactt gacagacagt ctcaagggtg tttatgacat
    38221 tgagcgcttg gctagtcgtg tttcttttgg caaaaccaat ccaaaggatc tcttgcagtt
    38281 ggcgactacc ttgtctagtg tgccacggat tcgtgcgatt ttagaaggga tggagcaacc
    38341 tactctagcc tatctcatcg cacaactgga tgcaatccct gagttggaga gtttgattag
    38401 cgcagcgatt gctcctgaag ctcctcatgt gattacagat gggggaatta tccggactgg
    38461 atttgatgag actttagaca agtatcgttg cgttctcaga gaagggacta gctggattgc
    38521 tgagattgag gctaaggagc gagaaaactc tggtatcagc acgctcaaga ttgactacaa
    38581 taaaaaggat ggctactatt ttcatgtgac caattcgcaa ctgggaaatg tgccagccca
    38641 ctttttccgc aaggcgacgc tgaaaaactc agaacgcttt ggaaccgaag aattagcccg
    38701 tatcgaggga gatatgcttg aggcgcgtga gaagtcagcc aacctcgaat acgaaatatt
    38761 tatgcgcatt cgtgaagagg tcggcaagta catccagcgt ttacaagctc tagcccaagg
    38821 aattgcgacg gttgatgtct tacagagtct ggcggttgtg gctgaaaccc agcatttgat
    38881 tcgacctgag tttggtgacg attcacaaat tgatatccgg aaagggcgcc atgctgtcgt
    38941 tgaaaaggtt atgggggctc agacctatat tccaaatacg attcagatgg cagaagatac
    39001 cagtattcaa ctggttacag ggccaaacat gagtgggaag tctacctata tgcgtcagtt
    39061 agccatgacg gcggttatgg cccagctggg ttcctatgtt cctgctgaaa gcgcccattt
    39121 accgattttt gatgcgattt ttacccgtat cggagcagca gatgacttgg tttcgggtca
    39181 gtcaaccttt atggtggaga tgatggaggc caataatgcc atttcgcatg cgaccaagaa
    39241 ctctctcatt ctctttgatg aattgggacg tggaactgca acttatgacg ggatggctct
    39301 tgctcagtcc atcatcgaat atatccatga gcacatcgga gctaagaccc tctttgcgac
    39361 ccactaccat gagttgacta gtctggagtc tagtttacaa cacttggtca atgtccacgt
    39421 ggcaactttg gagcaggatg ggcaggtcac cttccttcac aagattgaac cgggaccagc
    39481 tgataaatcc tacggtatcc atgttgccaa gattgctggc ttgccagcag accttttagc
    39541 aagggcggat aagattttga ctcagctaga gaatcaagga acagagagtc ctcctcccat
    39601 gagacaaact agtgctgtca ctgaacagat ttcactcttt gatagggcag aagagcatcc
    39661 tatcctagca gaattagcta aactggatgt gtataatatg acacctatgc aggttatgaa
    39721 tgtcttagta gagttaaaac agaaactata aaaccaagac tcactagtta atctagctgt
    39781 atcaaggaga cttctttgac aattctccac ttttttgcta gaataacatc acacaaacag
    39841 aatgaaaagg agctgacgca ttgtcgctcc cttttgtcta ttttttaagg agaaagtatg
    39901 ctgattcaga aaataaaaac ctacaagtgg caggccctgg cttcgctcct gatgacaggc
    39961 ttgatggttg ctagttcact tctgcaaccg cgttatctgc aggaagtctt aggcgccctc
    40021 cttactggga aatatgaagt tatttatagt atcggggctt ggttgattgg tgtggccgta
    40081 gtcggtctag ttgctggtgg actcaatgtt gtcctcgcag cctatattgc ccaaggagtt
    40141 tcatccgacc ttcgggagga tgccttccgt aaaattcaaa ccttttctta tgctgatatt
    40201 gaacaattta atgcgggaaa tctagtcgtt cgaatgacaa atgatatcaa ccagattcag
    40261 aacgttgtca tgatgacctt ccaaattctt ttcagacttc ccctcttgtt catcggttcg
    40321 tttatcctag cggttcaaac cttaccttct ctgtggtggg tgattgttct catggtagtc
    40381 ttgatttttg gtttgactgc tgtcatgatg ggaatgatgg ggcctcgttt tgctaaattt
    40441 caaacccttc ttgagcgcat caatgccatt gccaaggaaa atttacgtgg cgttcgtgtg
    40501 gtcaagtcct ttgtccaaga aaaagagcaa tttgctaagt ttacagaggt ctcagacgag
    40561 cttcttggtc aaaaccttta cattggttat gccttttcag tagtggaacc ctttatgatg
    40621 ttggttggtt acggggcggt cttcctctct atttggctgg tcgcgggaat ggttcagtcg
    40681 gatccgtctg ttgttggttc catcgcttct tttgttaatt acctaagcca gattatcttt
    40741 accattgtta tggttggatt tttgggaaat tctgtcagcc gtgccatgat ttccatgcgt
    40801 cgtattcgag aaattcttga cgcagagcca gctatgacct tcaaggatat cccagatgaa
    40861 gagttggttg gaagtcttag ctttgaaaat gtgaccttta cctatccaat ggacaaggaa
    40921 ccgatgctga aagatgtgag ctttactatt gaacctggtc aaatggttgg tgtagttgga
    40981 gcgactggtg caggaaagtc aaccttggct caattgattc cacgtctctt tgatccacag
    41041 gacggggcca ttaaaatcgg tggcaaggat attcgagaag tgagtgaagg aaccctgcgt
    41101 aaaacagttt ccatcgttct ccaacgtgcc attcttttta gtggaacgat tgcagataac
    41161 ttgagacagg ggaaggggaa tgctactcta tttgaaatgg agcgcgcagc caatattgcc
    41221 caggctagtg aattcattca tcgtatggag aaaacctttg aaagtccagt tgaagaacgg
    41281 ggaaccaatt tctctggtgg acaaaaacaa aggatgtcga ttgcgcgtgg gattgtcagc
    41341 aatccacgta ttctgatttt tgacgattcg acctcagcct tggatgccaa atcagagcgc
    41401 ttggtgcaag aagctttgaa taaggacttg aaggggacga caaccattat tattgctcaa
    41461 aaaattagct cggttgtcca tgcagacaag atcttggttc taaatcaagg acgattgatt
    41521 ggtcaaggca cgcatgcaga cttggttgcc aacaatgccg tttaccgtga aatctatgaa
    41581 acacagaaat gaaagacaaa ctataagaaa agtcaatagt tttatctaaa ctatttctta
    41641 tttcaatttg atgatttggc gatgatttta gagcacggca aaaagccctt gaaaaagtcc
    41701 attttttcaa aggtaatcct gtgttgattt cagaaattac atcacttttt gttcgtcaaa
    41761 tggcagctct tttttaggat ataaaacagg gttcggataa gtttttttgc aaggtggatg
    41821 atggctacat tgtaatgttt tccttattct aacttagtct taagataggc cttaaaagca
    41881 ggtgaaaagc gagcgcatgc tttggcagct tgtatgagtg cctaccgcag atgaggggaa
    41941 ccccgtttga tcattcttcc agctaaatca atctgacctg actgataaat agaagaatcc
    42001 agtccagcga aagcttgtaa ttgagcagga ttatcaaagg catgaatatt ttgaatctcg
    42061 gctaaaatga ccgcccctaa acgattccca atcccagtaa ccgtcgtgat gaccgaattt
    42121 aactcagcca tcaagtcatt gacacatttt tccgccttgt caatgagcct cttgtaatgt
    42181 ttgatgtttt cattacacga gataaaacgt ctatgcgtta tcaaactcat taccaattaa
    42241 aacaaatgtg gttagatcct ttcggaaatt gtcaagcgat tggaggaaat gaactaatcc
    42301 acagcggctt attccaagta taccacttgg gctttggcag tagctaactg cgctaaatat
    42361 aatataagga ggagtaaaat gaagacagtt caattttttt ggcattattt taaggtctac
    42421 aagttctcat ttgtagttgt catcctgatg attgttctgg cgacttttgc ccaagccctc
    42481 tttccagtct tttctggaca agcggtgacg cagctagcca atttagttca agcttatcaa
    42541 aatggcaatc cagaacttgt atggcaaagc ctatcaggaa tcatggtcaa tcttggcctg
    42601 ctggttttgg ttctatttat ctctagtgta atatacatgt gtctcatgac gcgcgtgatt
    42661 gcagaatcga ccaacgagat gcgcaaaggt ctctttggta agcttgctca gttgacggtt
    42721 tctttctttg accgtcgaca agatggcgat atcctgtctc attttaccag tgatttggat
    42781 aatatcctcc aagcctttaa cgaaagcttg attcaggtca tgagcaatat tgttttatac
    42841 attggtctga ttcttgtcat gttttcgaga aatgtgacgc tggctctcat caccattgcc
    42901 agcaccccat tggctttcct tatgctgatt ttcatcgtga aaatggcacg caaatacacc
    42961 aacctccagc agaaagaggt agggaagctc aacgcctata tggatgagag catctcaggc
    43021 caaaaagccg tgattgtgca aggaattcaa gaggatatga tggcaggatt tcttgaacaa
    43081 aatgagcgcg tgcgcaaggc aacctttaaa ggaagaatgt tctcaggaat tcttttccct
    43141 gtcatgaatg ggatgagcct gattaataca gccatcgtca tctttgctgg ttcggctgta
    43201 cttttgaatg ataagtctat tgaaacaagt acagccctag gtttgattgt tatgtttgca
    43261 caattttcac agcagtacta ccagcctatt atccaagttg cagcgagttg gggaagcctt
    43321 cagttggcct ttactggagc tgaacgaatt caggaaatgt ttgatgcaga ggaggaaatc
    43381 cgacctgaaa aggctccaac cttcactaag ttgcaagaaa gtgttgaaat cagtcatatc
    43441 gatttttcat acttgcctga taaacctatt ttgaaagatg tcagcatttc tgcccctaaa
    43501 ggccagatga cagcagttgt tgggccgaca ggttcaggaa aaacgactat tatgaacctc
    43561 atcaatcgct tttatgatgt tgatgctggt ggtatttatt ttgatggtaa agacattcgt
    43621 ggctatgact tagatagtct tagaagcaag gtgggaattg tattgcaaga ttcggtcttg
    43681 tttagcggaa cgattcgaga caatatccga tttggtgtgc cagatgctag tcaggaaatg
    43741 gttgaggtag cagcaaaagc aacccacatt cacgactata tcgaaagttt gcctgataag
    43801 tacgatactc ttattgatga tgaccagagc atcttttcaa cagggcagaa gcaattgatt
    43861 tcaatcgctc gaaccctgat gacagatcca gaagttctca ttctcgatga agcaacttca
    43921 aacgtagata cggtgacaga aaacaagatt cagcatgcca tggaggtggt tgtagcaggt
    43981 agaactagtt tcgtcattgc ccaccgcttg aaaaccattc tcaatgcaga tcagattatt
    44041 gtccttaaag atggagaagt cattgaacgt ggtaaccacc atgaactttt gaagctaggt
    44101 ggcttttatt cagaactcta tcacaatcaa tttgttttcg aataagaaag aagttgtcct
    44161 atgtgggcag ctttttcttg tccataaaaa atgtttatca cagccttaaa aaaaacatat
    44221 tagacgaaag tcattttgag tgatatgata ggactatcgt tagcattcga aaggagaggc
    44281 atcatggcta gaacggttgt aggagttgct gcaaatctat gtcccgtaga cgcagaaggc
    44341 aaaatcattc attcatctgt atcttgtaga ttcgcagaga tcattcgtca aatcggtggt
    44401 ctccctttag tcattcctgt tggtgatgag tcagttgtac gtgattatgt ggaaatgatt
    44461 gacaaactca ttttgacagg aggccaaaat gttcatcctc agttttatgg agagaaaaag
    44521 accgtcgaga gcgatgatta caatctggtc cgtgacgaat ttgaattggc actcttgaag
    44581 gaagcgcttc gtcagaataa accaattatg gcaatctgtc gcggtgtcca acttgtcaat
    44641 gttgcctttg gtggaaccct caatcaagaa atcgaaggtc actggcaagg actacctttc
    44701 gggacatctc actctattga gacagtagaa ggaagcgtgg tggctaagct atttgggaaa
    44761 gaaagtcagg tcaactcagt ccatcgtcaa agcattaaag atttggcacc taatttccgt
    44821 gtaactgcta ttgattcaag agaccaaact attgaagcga ttgagtctat cgacgagcac
    44881 cgcattatcg gtttacagtg gcatccagag tttctggtta atgaagaaga tggcaattta
    44941 gaattatttg agtatttatt gaatgaactg taacgattgg aacatctggt cgttctttct
    45001 tttatttttt caaaattttt agaatgtggc attttacgca aacgtttgaa ttctgataaa
    45061 aattggagaa attcgacaaa aaaacttgaa aaaaacgaag gtaagcgtta tgatagaaaa
    45121 gaagaaatat tggaggaaga acatgtcaca tattaaattt gattattcaa aagttttaga
    45181 caaatttgtt gcaccacatg aagtggaata catgcaatca caagtaacag cagcagatga
    45241 attgatccgt aaaggaactg gtgctggtag cgacttcttg ggatggttgg accttcctga
    45301 aaaatacgat cgcgaagaat ttgaccgcat cttgaaagct gctgagcaaa tcaagtcaga
    45361 cagcgatgtt ttggttgtga tcggtattgg tggatcttac cttggtgcaa aagcagcaat
    45421 cgacttcttg aatcaccatt ttgctaactt gcaaacaaaa gaagaacgca aagctccaca
    45481 aatcctttac gcaggaaact caatctcatc tacttacctt gctgacttgg tagagtatgt
    45541 tgcagacaaa gacttctcag taaacgtaat ttctaaatca ggtacaacaa ctgaaccagc
    45601 gattgctttc cgtgtcttta aagaactctt ggttaagaaa tacggtcaag aagaagctaa
    45661 caaacgtatc tatgcaacaa ctgaccgcca aaagggtgct gttaaggttg aagcagacgc
    45721 taacggttgg ggaacatttg ttgttccaga tgatatcggt ggacgcttct cagtattgac
    45781 agccgttggt ttgcttccaa tcgcagcatc aggagctgac atcaaagctc ttatggaagg
    45841 tgcgaatgca gctcgcaaag actacacttc agacaaaatc tctgaaaacg aagcttacca
    45901 atacgcagct gttcggaaca tcctttatcg taaaggctat gcaactgaga tcttggtaaa
    45961 ctatgagcca tcacttcaat acttctcaga atggtggaaa caattggctg gtgaatcaga
    46021 aggaaaagac caaaaaggta tctacccaac ttcagccaac ttctcaactg acttgcactc
    46081 acttggtcaa tttatccaag aaggaactcg tatcatgttt gaaacagttg tccgtgttga
    46141 caaacctcgt aaaaacgtgc ttattcctac tttggaagaa gaccttgacg gacttggtta
    46201 ccttcaagga aaagacgttg actttgtaaa caaaaaagca actgacggtg ttcttcttgc
    46261 ccacacagat ggtgatgtac caaacatgta tgtgactctt ccagagcaag acgctttcac
    46321 tcttggttac actatctact tcttcgaatt ggcaattgcc ctttcaggtt acttgaatgc
    46381 tatcaaccca tttgaccaac caggtgttga agcttataaa cgtaacatgt ttgcccttct
    46441 tggaaaacca ggatttgaag aattgagcaa agaacttaac gcacgtctat aatagaagaa
    46501 aagagtggtt tgcccactct ttttactctc tttatccata gaaattggac tcagccaaga
    46561 cttgtgatat aatatagaaa gcaaaaaggc agacgcctag ataataggag aaactatgtc
    46621 aaaagatatc cgcgtacgtt acgcaccaag tccaacagga ctactacaca tcggaaatgc
    46681 tcgtacagca ttgtttaatt acttgtattc gcgccatcat ggtggaacat ttctcatccg
    46741 tatcgaagat actgaccgta aacgccatgt cgaggatggt gaacgttcac aacttgaaaa
    46801 ccttcgctgg ttaggcatgg attgggatga aagtccagaa tcacatgaga attatcgcca
    46861 gtctgagcgt ttggacttgt atcaaaaata cattgaccaa ctattagctg aaggaaaagc
    46921 ctataaatct tacgttacag aagaagagtt ggcagctgaa cgcgaacgcc aagaagtagc
    46981 tggcgaaaca ccacgctaca tcaatgaata ccttggtatg agtgaagaag aaaaagcagc
    47041 ttacatcgca gaacgtgaag cagcagggat catcccaact gttcgtttgg ctgtcaatga
    47101 gtcaggtatc tacaagtggc atgatatggt caaaggcgat atcgaatttg aaggtggcaa
    47161 tatcggtggt gactggatta tccaaaagaa agacggttac ccaacttaca actttgccgt
    47221 tgccatcgat gaccatgata tgcaaatctc tcatgttatc cgtggagacg accatattgc
    47281 taacacacca aaacagctca tggtttatga agcacttggt tgggaagctc cagagtttgg
    47341 tcacatgacc ttgattatca actctgagac tggtaagaag ttatctaaac gtgatactaa
    47401 tacacttcaa tttatcgaag attaccgaaa gaaaggttac cttccagaag cagtctttaa
    47461 ctttattgct cttcttggtt ggaacccagg tggtgaagat gagattttct ctcgtgaaga
    47521 actcattaaa ctttttgatg aaaaccgcct cagcaagtca ccagcagcct ttgatcagaa
    47581 aaaactagac tggatgagca atgattatat caagaatgca gaccttgaaa ccatctttga
    47641 aatggcaaaa ccattcttag aggaagcagg ccgtttgact gacaaggctg aaaaattagt
    47701 tgagctctat aaaccacaaa tgaaatcagt agatgagatt atcccattga cagatctttt
    47761 cttctcagat ttcccagaat tgacagaagc agagcgcgaa gtcatgacgg gtgaaacagt
    47821 tccaacagtt cttgaagcat tcaaagcaaa acttgaagcg atgacagatg ataaatttgt
    47881 gacagaaaat atcttcccac aaattaaagc agttcaaaaa gaaacaggta ttaaagggaa
    47941 aaatcttttc atgcctattc gtatcgcagt ttcaggcgaa atgcatgggc cagaattacc
    48001 agatacaatt ttcttgcttg gacgtgaaaa atcaattcag catatcgaaa acatgctaaa
    48061 agaaatctct aaataaagag gatacaataa tggacatctg ggaaaagatg tacgaagaag
    48121 cacagaaact atacaatcca catgaagtat cagactttgt ttatgccaat catgttgtag
    48181 ctgcagtaga agcagaagat ggacaaatat ttacaggatt ctgtatggag ggaacctgtg
    48241 gtgttttcca tctctgcgca gaacgggcgg ccctcttcaa tatgtaccaa ttttcaggac
    48301 aaactaaggt taagaaagta ttagcctttc gagacaaacc accttatggt ggaagttcag
    48361 ccatgccttg cggtgcttgt agagaattcc ttttagagct taatgctgaa aataaagatg
    48421 cagaattcat gatggactat aatataagaa aaacagttaa agtcgcagaa ctaatccctt
    48481 attggtgggg agaagaacgt gcttctaagt ttaatgagcg atagaagagt cagtataatt
    48541 ctggcttttt ttactataag ttgaaaaaat
//
LOCUS       DAVHKZ010000011        48008 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000011 DAVHKZ010000000
VERSION     DAVHKZ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48008
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.011"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            108..764
                     /locus_tag="VVO74_000790"
     CDS             108..764
                     /locus_tag="VVO74_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEU5694835.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSIWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            754..1077
                     /locus_tag="VVO74_000791"
     CDS             754..1077
                     /locus_tag="VVO74_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEU5694836.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1181..2011
                     /locus_tag="VVO74_000792"
     CDS             1181..2011
                     /locus_tag="VVO74_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5694837.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2165..3019
                     /locus_tag="VVO74_000793"
     CDS             2165..3019
                     /locus_tag="VVO74_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU5694838.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEETS
                     DGLDQPVW"
     gene            3119..4492
                     /locus_tag="VVO74_000794"
     CDS             3119..4492
                     /locus_tag="VVO74_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU5694839.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESCTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEDRMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4485..5546
                     /locus_tag="VVO74_000795"
     CDS             4485..5546
                     /locus_tag="VVO74_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU5694840.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            5548..6240
                     /locus_tag="VVO74_000796"
     CDS             5548..6240
                     /locus_tag="VVO74_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5694841.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6270..6839)
                     /locus_tag="VVO74_000797"
     CDS             complement(6270..6839)
                     /locus_tag="VVO74_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU5694842.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            6974..7588
                     /locus_tag="VVO74_000798"
     CDS             6974..7588
                     /locus_tag="VVO74_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU5694843.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7590..9236
                     /locus_tag="VVO74_000799"
     CDS             7590..9236
                     /locus_tag="VVO74_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU5694844.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQASYSDQRQ
                     SIGIINVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9248..10534
                     /locus_tag="VVO74_000800"
     CDS             9248..10534
                     /locus_tag="VVO74_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5694845.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATVSHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFAIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10595..11128
                     /locus_tag="VVO74_000801"
     CDS             10595..11128
                     /locus_tag="VVO74_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5694846.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRTAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11206..11676
                     /gene="nrdI"
                     /locus_tag="VVO74_000802"
     CDS             11206..11676
                     /gene="nrdI"
                     /locus_tag="VVO74_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU5694847.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(11969..13231)
                     /locus_tag="VVO74_000803"
     CDS             complement(11969..13231)
                     /locus_tag="VVO74_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU5694848.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13541..13999)
                     /locus_tag="VVO74_000804"
     CDS             complement(13541..13999)
                     /locus_tag="VVO74_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU5694849.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(13996..14436)
                     /locus_tag="VVO74_000805"
     CDS             complement(13996..14436)
                     /locus_tag="VVO74_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5694850.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14869..15735
                     /locus_tag="VVO74_000806"
     CDS             14869..15735
                     /locus_tag="VVO74_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5694851.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLNALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            16072..16629
                     /locus_tag="VVO74_000807"
     CDS             16072..16629
                     /locus_tag="VVO74_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HEU5694852.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            16850..17956
                     /locus_tag="VVO74_000808"
     CDS             16850..17956
                     /locus_tag="VVO74_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HEU5694853.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGSA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            17932..19323
                     /locus_tag="VVO74_000809"
     CDS             17932..19323
                     /locus_tag="VVO74_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694854.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            19320..20498
                     /locus_tag="VVO74_000810"
     CDS             19320..20498
                     /locus_tag="VVO74_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU5694855.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            20923..21156
                     /locus_tag="VVO74_000811"
     CDS             20923..21156
                     /locus_tag="VVO74_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU5694856.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            21439..23388
                     /gene="mutL"
                     /locus_tag="VVO74_000812"
     CDS             21439..23388
                     /gene="mutL"
                     /locus_tag="VVO74_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU5694857.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(23713..24180)
                     /locus_tag="VVO74_000813"
     CDS             complement(23713..24180)
                     /locus_tag="VVO74_000813"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU5694858.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(24181..25386)
                     /locus_tag="VVO74_000814"
     CDS             complement(24181..25386)
                     /locus_tag="VVO74_000814"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU5694859.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(25406..26041)
                     /gene="ribE"
                     /locus_tag="VVO74_000815"
     CDS             complement(25406..26041)
                     /gene="ribE"
                     /locus_tag="VVO74_000815"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU5694860.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(26026..27126)
                     /gene="ribD"
                     /locus_tag="VVO74_000816"
     CDS             complement(26026..27126)
                     /gene="ribD"
                     /locus_tag="VVO74_000816"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU5694861.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(27260..27374)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            27531..28124
                     /gene="ruvA"
                     /locus_tag="VVO74_000817"
     CDS             27531..28124
                     /gene="ruvA"
                     /locus_tag="VVO74_000817"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU5694862.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            28134..28697
                     /locus_tag="VVO74_000818"
     CDS             28134..28697
                     /locus_tag="VVO74_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU5694863.1"
                     /translation="MTKRCSWVKMTNPLYITYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            28694..29371
                     /locus_tag="VVO74_000819"
     CDS             28694..29371
                     /locus_tag="VVO74_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5694864.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALIHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(29508..30538)
                     /locus_tag="VVO74_000820"
                     /pseudo
     CDS             complement(29508..30538)
                     /locus_tag="VVO74_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
     gene            complement(30793..31476)
                     /locus_tag="VVO74_000821"
     CDS             complement(30793..31476)
                     /locus_tag="VVO74_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU5694865.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(31488..32432)
                     /locus_tag="VVO74_000822"
     CDS             complement(31488..32432)
                     /locus_tag="VVO74_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU5694866.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            32564..35395
                     /gene="uvrA"
                     /locus_tag="VVO74_000823"
     CDS             32564..35395
                     /gene="uvrA"
                     /locus_tag="VVO74_000823"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU5694867.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILASVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            35388..36449
                     /locus_tag="VVO74_000824"
     CDS             35388..36449
                     /locus_tag="VVO74_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU5694868.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASSLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            36581..36979
                     /gene="spx"
                     /locus_tag="VVO74_000825"
     CDS             36581..36979
                     /gene="spx"
                     /locus_tag="VVO74_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU5694869.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            37045..37614
                     /locus_tag="VVO74_000826"
     CDS             37045..37614
                     /locus_tag="VVO74_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU5694870.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGTATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            37701..37967
                     /locus_tag="VVO74_000827"
     CDS             37701..37967
                     /locus_tag="VVO74_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU5694871.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            37971..38390
                     /gene="ruvX"
                     /locus_tag="VVO74_000828"
     CDS             37971..38390
                     /gene="ruvX"
                     /locus_tag="VVO74_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU5694872.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            38406..38711
                     /locus_tag="VVO74_000829"
     CDS             38406..38711
                     /locus_tag="VVO74_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU5694873.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            38970..40220
                     /locus_tag="VVO74_000830"
     CDS             38970..40220
                     /locus_tag="VVO74_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU5694874.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKDGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMREGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            40217..40759
                     /locus_tag="VVO74_000831"
     CDS             40217..40759
                     /locus_tag="VVO74_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU5694875.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            40905..42437
                     /gene="cls"
                     /locus_tag="VVO74_000832"
     CDS             40905..42437
                     /gene="cls"
                     /locus_tag="VVO74_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU5694876.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIMEIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            42515..42658
                     /locus_tag="VVO74_000833"
     CDS             42515..42658
                     /locus_tag="VVO74_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694877.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            42695..44233
                     /locus_tag="VVO74_000834"
     CDS             42695..44233
                     /locus_tag="VVO74_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU5694878.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     YFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILY
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            44353..46560
                     /gene="nrdD"
                     /locus_tag="VVO74_000835"
     CDS             44353..46560
                     /gene="nrdD"
                     /locus_tag="VVO74_000835"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU5694879.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTD"
     gene            46572..46712
                     /locus_tag="VVO74_000836"
     CDS             46572..46712
                     /locus_tag="VVO74_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694880.1"
                     /translation="MGKYQLDDKGCAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            46756..47262
                     /locus_tag="VVO74_000837"
     CDS             46756..47262
                     /locus_tag="VVO74_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5694881.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            47255..47845
                     /gene="nrdG"
                     /locus_tag="VVO74_000838"
     CDS             47255..47845
                     /gene="nrdG"
                     /locus_tag="VVO74_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU5694882.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            47853..>48008
                     /locus_tag="VVO74_000839"
     CDS             47853..>48008
                     /locus_tag="VVO74_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside-triphosphate reductase"
                     /protein_id="HEU5694883.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNPNY"
BASE COUNT        14469 a         8631 c        10401 g        14507 t
ORIGIN      
        1 ttttgagctg actacgtcag ttctatctgc ttttcattga gtactattaa gacaatatga
       61 ggagaaagat gaaagaaaaa ggattttagg agggggcgca ggcagccatg ccaacggctc
      121 ttggctatgt cagtatcggc ctggcctgtg ggactatcgg tgcgccctat gtgacacctg
      181 ttgagatggg cttgatgagt ctctttgttt atgctgggag tgcccagttt gccatgttgg
      241 cactgattgt ggttcaagct cctgtggcag ctattgctat gacggttttt ctaatcaact
      301 tgcgtctctt tttgttgagt ttacacgcat cgacttattt ccgtcatacc agtatttggt
      361 acaatatcgg tatgtctagt atcttgacag atgagaccta tggcgttttg atgggtgaat
      421 tggcccatac agacaaggta aatcctatgt ggatgcacgg aaacaatctt aacagctatg
      481 tggcttggtt tgtggggaca gtagtcggaa cggctctggg tggcctgcta ccaaatccag
      541 aaatctttgg cttggatttt gccctggttg ggatgtttat tggtattttt gcttcgcaat
      601 ttcagattat gcaaagacgg attcctgtcc gcaatctgct cattatccta gcagttgttg
      661 cggtgtcctt ctttttgctc ttgacagtgg tgtctcagtc actagctgtt ctgtttgcga
      721 cgctacttgg ttgtagcatg ggggtggttt tagatggtca gtaagtatct tttattagca
      781 gttattttct ctggcttggt gacttggatt ctccgtatga ttcccttcat cttagtcaag
      841 tataagggct tgcctgcaat cgttgagcgt tttttgaagt tcttgcccgt ttccattatc
      901 tttgccttga ttctttcaag cgtagtgaca ggtaaggttg ggagccttcc tcaaattaaa
      961 tggctagact tcttagccgt ctttccaaca gcttgggtag cctttcgcta ccgcaatcta
     1021 gtcggaacag ttctctttgg agtggtcttg attgccatct tgcgtttggt cttttaaatt
     1081 acccataaaa aaaacttatc acagagatag atatcatata atggcgtaaa tgctcttttt
     1141 ctgttaagat tataaggtat tctattttgg aggaaatgac atgaaaaaaa tcgttaaata
     1201 ctcatctctt gctgccctag gacttgttgc tgcaggtgtg cttgcggctt gctcaggggg
     1261 tgctaagaaa gaaggagaag cagctagcaa gaaagaaatc atcgttgcaa ccaatggatc
     1321 accaaggcca tttatctatg aagaaaatgg cgaattgact ggttacgaga ttgaagtcgt
     1381 tcgcgctatc tttaaagatt ctgacaaata tgatgtcaag tttgaaaaga cagaatggtc
     1441 aggtgtcttt gctggtcttg acgctgaccg ttacaatatg gctgtcaaca atcttagcta
     1501 cactaaagaa cgtgcggaga aatacctcta tgccgcacca attgcccaaa atcctaatgt
     1561 ccttgtcgtg aagaaagatg actctagtat caagtctctc gatgatatcg gtggaaaatc
     1621 gacggaagtc gttcaagcca ctacatcagc taagcagtta gaagcataca atgctgaaca
     1681 cacggacaac ccaactatcc ttaactatac taaggcagac ttccaacaaa tcatggtacg
     1741 tttgagcgat ggacaatttg actacaagat ttttgataaa atcggtgttg aaacagtgat
     1801 caagaaccaa ggtttggaca acttgaaagt tatcgaactt ccaagcgacc aacaaccgta
     1861 cgtttaccca cttcttgctc aaggtcaaga tgagttgaaa tcatttgtag acaaacgcat
     1921 caaagaactt tataaagatg gaactcttga aaaattgtct aaacaattct tcggagacac
     1981 ttatctaccg gcagaagctg atattaaata atttcttgaa atcatccatt ctgagtaagg
     2041 tgggtggttt ctcagttttt agggatatag ttttaaacta tatatctgac tatctaataa
     2101 caatttgtga aatcaaacaa attgtgagat actagtacgg tattattttt aaggagaaag
     2161 aatcatgaaa atcaaaaaat ggcttggcct agcagccctt gctacagtcg caggtttggc
     2221 tcttgcagct tgcggaaact cagaaaagaa agcagacaat gcaacaacta tcaaaatcgc
     2281 aactgttaac cgtagcggtt ctgaagaaaa acgttgggac aaaatccaag aattggttaa
     2341 aaaagacgga attaccttgg aatttacaga gttcacagac tattcacaac caaacaaagc
     2401 aactgctgat ggcgaagtag atttgaacgc tttccaacac tataacttct tgaacaactg
     2461 gaacaaagaa aacggaaaag accttgtagc gattggagat acttacatct ctccaatccg
     2521 cctttactca ggtttgaatg gaagtgccaa caagtacact aaagtagaag acatcccagc
     2581 aaacggagaa atcgctgtac cgaatgacgc tacaaacgaa agccgtgcgc tttacttgct
     2641 tcaatcagct ggcttgatta aattggatgt ttctggaact gctcttgcaa cagttgccaa
     2701 catcaaagaa aatccaaaga acttgaaaat cactgaattg gacgctagcc aaacagctcg
     2761 ttcattgtca tcagttgacg ctgccgttgt aaacaatacc ttcgttacag aagcaaaatt
     2821 ggactacaag aaagcacttt tcaaagaaca agctgatgaa aactcaaaac aatggtacaa
     2881 catcattgtt gcgaaaaaag attgggaaac atcacctaag gctgatgcta tcaagaaagt
     2941 aatcgcagct taccacacag atgacgtgaa aaaagttatc gaagaaacat cagacggttt
     3001 ggatcaacca gtttggtaat aagaaacagg gaggtgggag agaaaattcc acctcttgct
     3061 tttgtataga gtatagattg taaagaagac tattcgttca tagaaaggta gagagaatat
     3121 ggtttttcct agcgaacaag aacagattga aaaatttgaa aaggatcatg tagtccaaca
     3181 ttattttgag gttttgcgta ccttgatttc taagaaatca gtctttgccc agcaggttgg
     3241 actcaaggaa gtcgcaaatt atctgggtga gattttcaag cgtgttggag ctgaagtgga
     3301 gattgatgag agctgtacag cgccctttgt catggcacat ttcaagagtt cgcgtccaga
     3361 tgccaagacc ttgattttct ataaccacta tgacactgtg ccagcggatg gggatcaggt
     3421 ctggacagag gatcctttta cgctttcggt ccgcaatggc ttcatgtatg ggcgtggggt
     3481 tgatgacgac aagggtcata tcacagctcg cttgagtgct ttgagaaaat atatgcagca
     3541 ccatgatgat ttacctgtca atatcagctt tatcatggag ggagcggagg aatcggcttc
     3601 aacagaccta gataagtatt tggaaaagca tgcagacaaa ctccgtgggg cggatttgtt
     3661 ggtctgggaa caagggacca aaaatgcctt ggaacagctg gaaatttctg gtggcaataa
     3721 ggggattgtg acctttgatg ccaaggtaaa aagcgctgat gtggatatcc actcgagtta
     3781 tggtggtgtt gtggaatcag ctccttggta tctcctccaa gccttacagt ctcttcgtgc
     3841 tgcggatggc cgtatcttgg ttgaaggctt gtacgaagaa gtacaagagc ccaatgaacg
     3901 agaaatggcc ttgctagaaa cttatggtca acgaaaccca gaggaagtta gtcggattta
     3961 tggattggag ttgcctctct tacaggagga tcggatggcc tttctaaaac gtttcttttt
     4021 cgagccagcg cttaatatcg aaggaatcca gtctggttat caaggtcagg gtgttaagac
     4081 tattttacct gcagaagcca gtgccaagct agaggttcgt ctggttccgg gcctagaacc
     4141 gcatgatgtt ctggaaaaaa ttcggaaaca gctagacaaa aatggctttg ataaggtaga
     4201 attatactat accttgggag agatgagcta tcgaagcgat atgagcgcac cagccattct
     4261 caatgtgatc gagttggcca agaaattcta tccacagggc gtttcagtct tgccgacgac
     4321 agcggggaca ggacctatgc atacggtctt tgatgcccta gaggtaccaa tggttgcatt
     4381 cggtctagga aatgccaata gccgagacca cggtggagat gaaaatgtgc gaatcgctga
     4441 ttattacacc catatcgaat tagtagagga gctgattaga agctatgagt agagatatta
     4501 tcaagttaga tcagatcgat gtgacttttc accaaaagaa gagaaccatc acagcggtta
     4561 aggatgtgac cattcacatc caagaagggg atatctacgg aatcgttgga tattctggag
     4621 cagggaaatc aacccttgta cgggtgatta atctcttgca aaaaccatct gcagggaaaa
     4681 ttaccattga cgacgatgtg atttttgatg gtaaggtcac cttgacggca gagcagttgc
     4741 gtcgtaaacg tcaagatatc ggaatgattt tccagcattt taacctgatg agccaaaaga
     4801 cagcagagga gaatgtagcc tttgccctta aacactctga actcagcaag gaagaaaaga
     4861 aggctaaagt agctaagttg ttggacttgg ttggtttggc agatcgtgct gaaaactacc
     4921 cttcacaact atctggaggg caaaaacagc gtgtggcaat tgcgcgtgcc ttggccaatg
     4981 atccaaaaat cttgatttca gacgagtcaa cttctgccct tgatccgaag acaaccaagc
     5041 agattttggc cttgttgcaa gatttgaacc aaaaattagg cttgactgtt gtcttgatta
     5101 cgcatgaaat gcagattgtc aaagacattg ccaaccgtgt ggcggttatg caggatgggc
     5161 atttgattga agagggtagt gtgcttgaaa tcttctcaga ccctaaacaa cctttgactc
     5221 aagactttat ctcaacagct acaggtattg acgaagccat ggtcaaaatc gagaagcaag
     5281 aaatcgtgga acacttgtct gaaaacagtc tcttggtgca actcaagtac gctggagctt
     5341 caacagacga gccacttttg aatgaattgt acaagcatta ccaagtaatg gctaatattc
     5401 tctatgggaa tatcgaaatt ctcgatggta ctcctgttgg agaattggtg gtggtcttgt
     5461 caggtgaaaa agcagcgttg gcaggtgccc aagaagctat tcgtcaagca ggcgtacagt
     5521 taaaagtatt gaagggagga cagtaagatg gaatcattga ttcaaaccta tttgccaaat
     5581 gtctataaga tgggttggtc tggtcaggca ggctggggaa cagctatcta cctaaccctc
     5641 tatatgacag ttctttcctt tatcatcgga ggcttcttgg ggctagtggc aggtcttttc
     5701 cttgtcttga cagcgccagg tggtgtcttg gagaataaag tcgtattctg gattttagac
     5761 aaaattacct caatttttcg tgcggttccc tttatcatcc tcttggcaat cttgtcacca
     5821 ctttctcact tgattgttaa aacaagtatc gggccaaatg cagcccttgt cccactttct
     5881 tttgcagtct ttgccttctt tgcccgtcag gtgcaggttg tcttggctga attggatggc
     5941 ggtgttattg aggcggctca agcgagcgga gcgactttct gggacatcgt gggtgtttac
     6001 ctatcagaag gtcttccaga tttgatccgt gtgacgactg tgaccttgat ttcccttgtt
     6061 ggggaaacag ctatggccgg tgcggttgga gctggtggta tcggtaacgt agccatcgct
     6121 tatggattta accgctacaa tcacgatgtg accatcttgg caaccattat tatcattttg
     6181 attatctttg caatccaatt cttgggagat ttcttgacta agaaattgag ccataaataa
     6241 aaaagagccg cgtggctctt tttaactgat cagattttct gtgcaaattt tttactcaag
     6301 gcttgtccaa tcaaagcacc cactagggct ccgatgacaa tacttgcgat aaatagaagg
     6361 acagtcccag ggtttggagc gaccatgata cggtcgatat attcttggga ttttcctctt
     6421 gccagaagag tagccatata ggctttgggc gcaatccaca taagcaagat tggtcctgtt
     6481 gtactaaagg cgaaaataat gaaagaaagg aagttctttg ttttgtcctt gtattttcct
     6541 aaatgagcta cttcatctgc taggaggcca cagataattc caggaaggaa ggaaccagca
     6601 ccgtgtttag ttcccaagaa aaagaaggca atgacaaggc cgatagtggt aatggctcca
     6661 aagcgcggaa cttttgcgac taggatcata tagacgctac cgccgacaag ggcagtaaag
     6721 gcaggcgcat aaaacatgtt tccagtttgg tcaaagagat tgcccaaaag gacaccaatc
     6781 cccatgcaga ggaagtaaag aactgcaaaa agcagtgtag ttaagataga tttcttcatg
     6841 aattgtctcc tgataatttt ttcacaattc tcattttacc atggtttggt gggattgtaa
     6901 atggatacta gaagtttttg aaaacgcttg aaatatgata taatggtttc atagttattt
     6961 ttaggggaat atcatgggta gatttttaga ctttgtcttt aatcgtttct ttttagggat
     7021 gattgcgaca gccttctttt ggctattaac tttagcagga gggattatcc ttggtctagc
     7081 gccggctagt gccaccttga tgagcttata tgcagaacat ggttatagct ttcgggaata
     7141 cagtttgaag gaggcttggt ctctttacaa gcaaaatttt gtctcaagca acctgatttt
     7201 ctatagcttt ttaggtgtgg gtctagtttt gacctatggt ttgtatctct tggtgcaatt
     7261 gcctcatcag accattgttc atttgattgc gacccttttg aatgtcctag tagttgccct
     7321 gatctttttg gcttatacag tatctttaaa attacaagtt tattttgcct tgtcctatcg
     7381 aaatagtctc aaattatcct tgattggcat ctttatgagt ctagcagctg tggccaaggt
     7441 tctccttggg actgtgctac ttgtagcaat tggttactat atgcctgccc tgctattttt
     7501 tgtaggaatt gggatgtggc atttctttat cagtgatatg ttggaacctg tctatgaaat
     7561 catccatgaa aaattggcga caaaatagaa tgaagcagtt ttggctacat acgcttctaa
     7621 gaacctatag ttcagtgatg atcattatca ttgcgagttt tgcaatctta ctctcttacg
     7681 ctgactggga ttcacgtgaa aaggaagccc agagagtagc ccagcgtgta actgctagaa
     7741 cagtgagtga aattgaatat taccatagag agtcaaccca gatagctcag gctttagttg
     7801 aaaatcaagc tcgtatcgag ggaatctata aatactttag ccttagcatg ccagactatt
     7861 tttactggca attagagcgg aaagcttcgc cttatatatc agtctctctg tatgaaaatg
     7921 ttgatgacct ctatgttcga aatgattttg taactggggt ggccattgct tttcaagatt
     7981 acaaggaagt ctatgtttct actaaagaca aacgtagtgg agaaaaaatc agggctgagg
     8041 atttcaaacc agcaggaaat agttttgcca ttccagtgtc agatccagtg tcagatcaag
     8101 acttaggagt gatttacatc tccttggatc ctgctgttct ataccatgcc attgataata
     8161 ctagaggtca tactccgatg gcagtaacag tgacctcacc ttttgatacg gagatttttc
     8221 atattggtga gacagttgat aaggagagtg aaaattggct agttggctta acttctcatg
     8281 gttatcaggt tcaggtggca gttcccaaaa actttgtttt acaaggaacg gtgaccagct
     8341 ctgctttgat tgtgggcttg agccttctct ttattgtcat tctttatctg actttgaggc
     8401 agacctttgc taattatcaa aagcaggtag tggatttggt ggattccatc caagctattg
     8461 cccaaggaca agaaggtctt cgcattgata cgcttgaaaa ggatcaggaa ttgctcctaa
     8521 tcgcggagac gaccaatgat atgttggatc gattggaaaa gaatatccat gatatttacc
     8581 agttagagct tagtcaaaaa gatgccaata tgcgagcctt gcaggcgcaa atcaatcctc
     8641 attttatgta taatacgctg gagttcttgc gcatgtatgc agttatgcag agtcaagatg
     8701 agttggcaga tatcatttat gaattcagta gtctcttgcg taacaatatt tccgacgaaa
     8761 gagagaccct cctcaaacag gaattagaat tttgccgtaa atacagctat ctctgcatgg
     8821 ttcgctatcc caagtccatt gcctatggtt tcaagataga tccagagtta gagaatatga
     8881 agattcccaa gtttaccttg caaccgctgg tagaaaacta tttcgcgcat ggtgttgacc
     8941 acaggcggac agataatgtg attagcatca aggctcttaa acaggatggt tttgtggaaa
     9001 ttttggtggt cgataatggt agaggaatgt cggctgaaaa gttggcaaat atccgagaaa
     9061 aattaagtca gaaatatttt gaacaccaag ccagctacag tgatcaaagg cagtctatcg
     9121 gaattatcaa tgtacacgag cgttttgtgc tctattttgg agaccgctat gccattacga
     9181 tagagtctgc agagcaagcc ggtgttcagt atcgtattac aattcaagat gagtagaaag
     9241 ggagaaaatg tataaagtat tattagtaga tgatgagtac atggtgacag aaggtctgaa
     9301 gcgtttgatt ccctttgata agtgggatat ggaggtcgtc gcaacagtca gtcatgccga
     9361 tgaagctcta gaatatgttc aggaaaatcc tgtcgatgtc atcatttccg atgtcaatat
     9421 gccagacaaa acagggcttg atatgattcg ggagatgaaa gagatcttac cagatgctgc
     9481 ctatatcctg ctctcaggtt atcaggagtt tgattatgta aaaagagcaa tgaaccttag
     9541 tgtggtggac tatttggtca agcctgttga taaggtagag ctgggaaatc tgctggagaa
     9601 gattgcaggt cagctcggcg agagagggaa gaaaagtcag actcttagtc aagaattaga
     9661 cgaggctgga tttgttagtt atttagggga taaggagaat tggtggatag gtctatccaa
     9721 ggaaaaacaa ggttccttcg ccattcccta ctatgtcttg ggccaagact ggcagatttt
     9781 catttctgac caacccctag atggtttagt cgttacacct tttgaagctc cttatcaaga
     9841 acactttgaa cgctggaagc tgaatgctga gaaaaccctc ttttacggtt ctgtaaatct
     9901 gcagcagtct gagagtctct ttgcctatta cgaaccgatt tatagggtta tcattcaggg
     9961 aaatctcaat caaatcgtag aagagttaaa tctcttggag aaggtagttc ttgaaaatac
    10021 gccgcgtgtt ccgattacta aacagctttt tattcagttt gtcatggatg ttttccattt
    10081 atttgaacat ctcaaagctg atgacctgac agacatcgtc aaaaccattc atgctattca
    10141 atccttcgat gaattggttc cttatatcaa ggaaactctg agcagctttt tcggtcaata
    10201 ccgtatgaat gaaaatgtgg tcagtgtgct ggaagtcatt ggtcgtgatt accaaaaaga
    10261 gctttccctc aaggatatca gtaaggctct ctttatcaat cctgtctatc tagggcagtt
    10321 gattaagcgt gaaaccgatt cgacttttgc agagttacta aacaaacaac gtattaaggc
    10381 tgcccaacaa cttttgcttt caactagtga cagcatcgaa gatatttgtt atgctgttgg
    10441 ttacagtaac cttggatatt tctataaagt tttccgaaaa ttgtgcggaa aatcgccaaa
    10501 agcctaccga aaacaggtag aaactatact ataagatttg tattccttta caaaatgtgc
    10561 tataatataa atattattat taggaggttc tatcatgaaa aagaaaccaa tttatctatg
    10621 ggtcttgcta atcttgtctg cccttatttc agttccgtct ctgtttggaa ttgtgagtcc
    10681 cttgcctagt aaagaagccc ttcgtactgc tcagaaacaa gttgcagggg tcaatgctca
    10741 gcaattagaa gaccagctta attataccta tagagtagca gaagcatctc attctatttt
    10801 taatgttgct ttgattgtgc tatctactat tttagtggtc gtagcgattg tcttccttgt
    10861 tcgtaaaaat ttgcaatatg caaactatac ttacgttggc tatgttttgt tagctattat
    10921 tggttcgatt tatggctatg ttggtttaca agacgctgtg cagttggttc aagatgagag
    10981 catgcgtttg acagtgagta ttggttcaaa agctgttagc attttctata tcgtcatcaa
    11041 tgttctcttc ctagcccttg tcttctataa gatgtggcga caacagaaag ccttggcaga
    11101 agaagaggaa acagaagagc ttgcctaagt attgacaaaa aagaactatc aagatacaat
    11161 cttggtagtt gttttttgat tatagataaa atcatggagg tacatatgaa gacaatttct
    11221 ttagtttata ttagtttgag tggcaacact gaaagttttg tgacgcgctt gaaagactat
    11281 ctcttgtccc agtacaaagg gattgaggtt caaaagattc atatcaagga tttggtcaag
    11341 gaaggcaaaa atttctatga aatggaccat ccctatgtcg cttttttgcc gacctatctc
    11401 gaaggtggga atggcgtgga taacggagat gttgagattt tgacgacacc ggtgggagat
    11461 tttattgcct atggtaacaa tgctagtaag tgttttggtg tggttgggtc aggaaatcgt
    11521 aactttaata accaatactg cctaacagcc aagcaataca gtcaacgctt tggcttccct
    11581 gtattggctg actttgaaat gcgaggcatg ctggaagata tcaaacatgt cgcagctatt
    11641 atcgcagatt tgtatgagtt ggaaaaggag aattaatact caatgaaaat caaagagcaa
    11701 actaggaagc tagtcgcagg ttgctcaaag cacagctttg aggttgcaga tagagctgac
    11761 gtggtttgaa gagattctcg aatagtataa agttcttata agaggtggtt gaagttgttc
    11821 aactgttttt tgagtataaa cagtttttaa gaacgtaaaa aagcataagt tcaggtcttc
    11881 aaaaccttgt tcttatgctt tttatcatag aaatatttgc tgaattttct cttgaaatga
    11941 aaccttatct tcatctcgcg cttgtccctt accctgcttt tccgattgcg agtgcgtaga
    12001 taaagaagat ggcgaagcca aagaggaaaa tcaatcccgc aatggcaagg tgtttgagcc
    12061 aagaaggaag atttttgttt tcacgcgtta ccaaggcgta attcaaaaga gcaaagaaag
    12121 gtgttgtcag gaaagaacca atcatggcaa agcggagcat ggttgaaacc tgaccagcga
    12181 agaacttgat aatgacgata ccgatgatag cagtgatggt catccagatg ttcaaagatt
    12241 tacgattgtc ctctttttga ctgattagca gtcggagaga ttcctgatta acgcgagaat
    12301 agccatcgat aacagttata actgttccaa agatacagag gaaggcaata aaggtaatca
    12361 agtaacggga ccattcgcca agaacagagg catacatgcc cacgaattga gagatgtatt
    12421 tggctgaagc agcttcaacc gcctgccctg taggatactg aatcagtgct cccagtgcca
    12481 caaagaagac ggctaggata gctgttccaa tataaccagt gttaaagtca aacagagcgt
    12541 cttctgtgtt aaagttgacg gtctttctct tttcagctga ccaaagtgaa ttgatggctg
    12601 aaatttcaat aggagccggc atccatccta ggagggagac gatgaagggc agagctgcca
    12661 tttgccaagg tgtcttctcg acaaaatcag aactgtattc tggatgcttg accgccgcaa
    12721 tgataactgc aagaacagtc gcaatggtta aggcagacat aatccatttg accatgccgt
    12781 ctaaaagttt gtagcctcca aagagtagca tagcccaaat gattgcaacg agaatgaggg
    12841 accactgagt aatgctaagt ccaatcattg ggaaggcact ggcgatgata gctgagcaca
    12901 gaatggcaac accagccgtg ttgaccatag ccgaaaagac attgaggata aagaaaatcc
    12961 agagatagag ttttcctttt tcggcataac cttcaaccaa agtctttcca gtatcagctg
    13021 tgtattcagc accaaaacgg aaaaatggat atttaaagac attggctaag atgaccaaga
    13081 gaagtagaga ccaaccgtaa gaaccgccag cttgagttga ggatacaatg tgggaacctc
    13141 caacagcggc agttgccatt aggattccag gtcccattgc ttttagcttg cttgcccagg
    13201 ttgattgatt taaggaaata gcttgcgaca tgataaatac tcctttttga attttcagaa
    13261 taatctgtat atgtaatcta tattctacaa aaaattttgg aaaaatgcaa gagtattttg
    13321 aaaaaagata gaaaatttac aaagaaaatc tgaaataact gttatgatat agaggattga
    13381 aactagaata gtacacctct gcttctaaaa cattgttaga aatcgatttg actgtcctga
    13441 tcgatttatc ctgttcttat ttcatttcac tatagtaagg tgcagcagga taaagaaaat
    13501 ccgagaagtt tctttctcgg atttgcttat tatgaggttc ctattttcta tgctccaaga
    13561 gttgattgat gtgatctact tttttagcct ctcttttata gagaatagcc cagatgatga
    13621 gatagacaat cgcaaactcg ataatgagct ggaggtagaa aatccagtgg aaagggaacc
    13681 aaccagcaag agttgctagt gggacaaagc cagccagcat aaggaagaaa tgagtcagag
    13741 tggcacgaag catgctccag tcacggctaa ataagcggtt gccaaagttg aagagcatac
    13801 cgatggttgc ccatataagt gtgcagtaga gcaagaccag ggcaccgtga acctgatgct
    13861 gatccatcac ttggccgatg agagagtagg gatttagtgg tgcgtaggta tttggtgcat
    13921 aaatgagtga aaagaggata gagaggatga ggccgataag aacaccggta gctgcatcgt
    13981 gaaatacttg ttttttcata gttctaattt ctccttgatg gtttttagat aacggcgtga
    14041 agagtaggtg aagctttcgt ttttcaagaa aatttctacc agaccgtttg gcgtgagctt
    14101 gaggtgagag atggaatcga tattgatgat ttctgattgg gaaatttgga taaaattggt
    14161 tggcaagagt ttaagaacct gatagagtcg caaatcaatg ctgtaggtct gactcgcggt
    14221 ttctgctaga accttccgat tctcgatata gaagcgctga atcttgccaa tctcaactag
    14281 atagacctga tcatcgattt ttcctttgat tttttctctt tggtccagat tttctgcgaa
    14341 ctcgatgact ttctggactt tttcggtttc ttgaggtgct tggacaatca gcttttcctc
    14401 ctcgtaagtc tcactaatct gtagttctac tttcatagtt ttctctcctt ttcagttata
    14461 caaggttgtg atcacttcct gtatatcctt attaaacact attttatagc ccatggcaag
    14521 gaaccttgtc tatgtggagg gattgggctc ctatgtggtg gagcttttct gttctttctg
    14581 aaatatggta taatagcact aatcaatttc taggaaaata gatacggaaa ggggctgaaa
    14641 gaactagggg aacagttgga attagaaagt gataggtatg aaaagtggcg ttgaagctga
    14701 ataagtttat aaagcgtttg aatgaagaaa tggaaagtaa ataagttgac gatgaattac
    14761 aaaatagatt ttatctacaa tttgtatctt tcaaatcatt gatttgaatt ttagatttaa
    14821 tcatgttaca attaaaactg aaatcaaata gaagaggaaa atgcaaacgt gggcacacta
    14881 ttagcaacaa gattaaaaaa tagacggaaa gaattaaaaa tgtctcagcg agaactagct
    14941 gaaggtatct gtaaacaggg gcaaatcagt cgattagaga gcggagagtt tacccctgga
    15001 gcggatttcc tgaatgccct tgctaagaag ttaaaagtca gtatggatta tttttttgat
    15061 gagcaggttg tagagaaagt tgaggagtta tcagaattta agaaattagc acagacattt
    15121 attacaaatc gcaattatga gtctttgaaa tatatatatg aattggagaa tgtaaaagct
    15181 caccgcctat ctttagcaga taaaatctac atggaatgga taaaatctct gatagatttt
    15241 tatttttacg gacagaaaga agatgcgatt gtacgattag agggggtatt atcacagtta
    15301 agtgtatctg atttgaacta tctccaagtt tcaaacaccc tattcaattt ttattatgat
    15361 attggagatt taggtcgttt caataaaatt cgtgaaaaac tagagtatca agtaaatcac
    15421 ctcaatttga gtacaatcga agagttagaa ctatctatta agtttaacta caacgtttgt
    15481 cgttatctat ggttacagaa aaatattgaa gaagctatta ctaaaattac agctactata
    15541 aaacaatgta aggcttacag aacgaattat cttttggctg atttgtactt attgatggga
    15601 aatgtaagtg aaaatttttc ttctaaaagt tcggtgaaag aatattttga gacggcatat
    15661 tttctataca aacttgagga gaacatgtca atgactctga aagttgagca ttacattgca
    15721 gatataacag aataatgaat acggtgttca agtgagcatc gtttttcaaa cctagttcag
    15781 atacaaaaaa gtatcaaaca aaaaaaaata aaaaaacatt ataaaaacaa ttgacaagct
    15841 aattttgaag tgataaatta aatgcaagaa aacaaaagga gaggtatatg agaagtttgt
    15901 ttaagaaaat agttgctgta ttagttattg gcttaattct gttaggaatt gcgagaacac
    15961 ctcaagttca taagatggct agagggattg atcctggtcc tgcgaatttt atttagaaat
    16021 caatttctac taattgagta ctaattgagt attaatgggt aaaaagattg tatggataag
    16081 aaaaatttac ttgtattggt tactggttcg gtaggtgcca gtaatgtaga tacatactta
    16141 tattatataa aaaaattcta taatgttaaa gtgatacttt ctgaaaattc taaaaaattt
    16201 ataagtaagg aattaattag ttatttttgt gataaagttt atgatgaaat atttgttgaa
    16261 gaggtagttc cgcacgtttt tctgccatat gaatctgact tacttcttat tttaccagct
    16321 acggcaaatg tgattggcaa aattgctaat ggtattgctg atgatttagt tacagcaact
    16381 gttttaaact ttaataaaaa aataattttt tgtcccaata tgaactctac tatgtgggac
    16441 aatcacatag ttcaaagaaa tgtatcaatt ctaaaggagt tgggacatat atttttattt
    16501 gagtctaaaa aaacatatga ggtaggattg cgtaaagcaa tagattcaac atgttcaatg
    16561 ttacaaccac agtcgttagt aaaagaactt atcaaattag aaaatattgt ccttgaagag
    16621 ggacattaaa aactactgag aatattaagg aggggaaaaa atggaaaatt catcaatcga
    16681 tgtagatatg ctgttggaag aattgacaca agaagcaatg gtcgttgttg ctgttgataa
    16741 ggactgttaa tttaaactta tggcaatata tgaaaggtta ctggatgttt taaattatgc
    16801 aggcagtagc cttttattat atacaaatgg ataaagtaag gataatacaa tgattaataa
    16861 aaaaatacaa caagttgttt tggaatcatt acagaatttt ttgaatggga acttcatttc
    16921 gccttgtgta gtctatgatt ttggcttgct ggaaactgta cttgatgaat ttaaaaatca
    16981 aattcctgta acattcaatt accaactttt ttatgccgtt aaagcaaatt caaatgagaa
    17041 gatacttgaa ttcttagtag ataaaattga tggagttgat gtggcgtcat tatctgaatt
    17101 agatgtggct aaaaaatttt tcccaccaac tcaaatttct gttaatggtt ccgcattttc
    17161 ttatgaaact ttatataatc tgattaaaaa acaatataaa gttgatatta actttttgga
    17221 acatcttcaa caattttccc caaaagaatc tgttggaata agagtaacgg agccagatga
    17281 acttaataat cgtatgagtc gatttggaat aaatatttgc agtgataatt ggactagtaa
    17341 tttacaaaat cctttaatta cacgactgca ttttcatttt ggagaaaaag atgataaatt
    17401 tattgttaag ttagataaaa tattatttaa gttacaagaa attaataaac ttagagaggt
    17461 tagagaaata aatcttggag gcggttttat gaaattattt atggaaaatc gtttgaaaga
    17521 attttttcta tcacttatgg aaatctataa aaagtacgat attgatagta ctgtgactac
    17581 aataatagaa ccaggtagtg caattacttc attttctgcc tatatgatta ctagcccagt
    17641 taatgttagt gaggtgaatg agcagcaggt tatcacgtta gacacatcaa tatacaccaa
    17701 tacattatgg tttgttccgc atattattac aacgttaaat tcaagtagta aagagcgtta
    17761 tagtactatt ctctatggta atacctgtta tgaacatgac aagtataaaa tgaaagtttc
    17821 gcttccaagg ttaactcaaa atagcagtat agtgtttttt cctgtaggag cttatataaa
    17881 aagcaatcat tcaaatttac atcgtaatga ttttatgcgg gaggtatatt tgtggacaaa
    17941 aaacttgaca tattagataa agttaaggaa tatttaggaa ataaaactac tcaaattctg
    18001 gataatcaat ataaagaatt tttgaaactt aatgatataa ggcgagcgtt tggtatttca
    18061 gaaaaagtat taaacaattc ttttaatttt acgagtaaag aatttaatga tttaattaat
    18121 aacgaaaatt atttattcga atatgcatgt agaattagag aggaatggag aaaaaaatgc
    18181 tttaatcatt cttatcgttt tctatgctca cctataatta cagatgattt tcttaacacg
    18241 aagacattga gaagtagcca aattgaatat aaatatgagc gatatttatc gaaaagttcg
    18301 ataggcgata gagcggttga tggctttgtt tccttcaata ctttaacagc taatggtatg
    18361 tctgctatta aactatgtct tgagatatta aactctattt tcttcaagaa gaagattgat
    18421 ttattatatt caaccggata ttatgaaaca agatttttat taaataatct tgctaaatca
    18481 ggtattagtt gctatgaggt aagtaattgt gaattggata aagataaatt ttataatgta
    18541 ttcatgatgg aacccaatcg agccgattta acattacaaa aaactgattt caagatagta
    18601 gaatattttg ttaagtataa aaataattca ataaaagtcg ttattttaga tatttcatat
    18661 caaggttcta attttaaatt agtagaattt ttagagaaat ttaaatttgc gaatgtaatt
    18721 atttttgtgg tacgatcttt gataaaatta gatcaaatgg gattagaatt gacaaatggg
    18781 ggaataatag aagtgtttat tcctaatcat ttgagaaagt tgaaaaattt tattgaagag
    18841 gaattcaata aatttagaaa ttctcacgga gctaatctaa gcctctatga atactgtttg
    18901 cttgataatt ctttaacttt aaaaaatgat tggaactatt ctgatttagt tatgaaattt
    18961 acgagtaatt tttatgctga tataaaagac ttgttcatgg aaaattctga tattgaaatc
    19021 atccatgaag agggagtacc ttttgtattt ttagatttaa taggtgaagg taaaaaagaa
    19081 tatgaaatgt tttttcaatg gttaaacttc ttttacaaac agcttggaat cacattgtat
    19141 gctagaaata gttttgggtt tcggaatcta acagtagagt attttggaat tattgggaca
    19201 gaaagatata tatttaagat ttgtccaggt gtttataaag ggttaagtta ttatttgatg
    19261 aaatttttat taaaatcttt ttcaaatgaa tatttaaaaa ctactgatga ggttaataga
    19321 tgaaaaattt gataaagttg ctaataatta gattgattgt taacttagca gacagtgtat
    19381 tttatatagt agcattgtgg cacgttagca ataattattc ttcgagcatg ttcttaggaa
    19441 tatttattgc agtaaattat ctaccggatt tgttactaat cttttttgga ccagttattg
    19501 acagagtaaa tccgcaaaaa attcttataa tatcaatttt ggttcaatta gcagtggctg
    19561 taatattttt attattatta aaccaaatat cattttgggt gataatgagt ctagtgttta
    19621 tttcagtaat ggctagctcc ataagttacg tgatagaaga tgtgttgatt cctcaagtgg
    19681 tagaatatga taagattgta tttgcaaatt ctctttttag tatttcgtat aaagtattag
    19741 attctatttt taattcattc gcatcatttt tacaggtggc agtaggattt attttattgg
    19801 ttaagataga tataggcata tttttacttg ctctatttat attgttgttg ttaaaattta
    19861 gaactagcaa tgcgaatata gaaaacttct ctttcaaata ttacaagaga gaagtgttgc
    19921 aaggtacaaa gtttatttta aataataaat tattatttaa aaccagtatt tctttaacgc
    19981 ttataaactt tttttattca tttcagacag tagttgtacc gattttttct attcgatatt
    20041 ttgatggtcc gattttttat ggtatttttt taactattgc tggtttgggt ggtatattgg
    20101 gaaatatgct agcgccaatc gtaataaaat atttaaaatc gaatcaaatt gttggtgtat
    20161 ttcttttttt gaacggctca agttggttag tagcaattgt tataaaagac tatactttat
    20221 cacttatttt atttttcgtt tgttttatgt ctaaaggagt cttcaatatt atttttaatt
    20281 cgttgtacca acaaatacct ccacatcaac ttcttggtag ggtaaatact accattgatt
    20341 ctattatttc ttttggaatg ccaattggta gtttagttgc aggaacgctt attgatttga
    20401 atattgaatt agtgttaatt gctattagca taccttattt tttgttttct tatatttttt
    20461 atacggataa tggattgaaa gaatttagta tatattagaa atgtttatgt tcattcaaaa
    20521 gcataatgac tataactgaa aaagaaaagt gatatcttta aggttgttct tcttggtggt
    20581 gagattcgtg agacaaccca agcttttgtc ggaaagatta ccaatgcttt gatggatagg
    20641 atgtacttta gcaagatgtt tttagtggta acggtatcgt ggatggacgt gtaataacct
    20701 cttctttcga ggagtatttt actaaaaaac tagccttgga gcgttcccca gaaacggact
    20761 tactcattga ctcttcaaag atttggggag aagattttgc ttcatctgtt ccttgaaaaa
    20821 agtcacagca gtcatcacag acgatagtac tgaacaaaac tatgaagagt tagaaattta
    20881 tacgcaggtg attgtataaa ggatctggaa atagataaga agttgattag tattgaccta
    20941 ggtggtacaa atattaagat tactgttctt tcaaatgacg gtgagattga aactttgtgg
    21001 agtattacaa cagatacaag tgagaaaggt tctcaaatta tatcggacat catcagttct
    21061 attaaaaata aattgaccga acggaatatt cctgatagcg accttcttgg aatcggtatg
    21121 ggaagttgct catcatactt tccttgtaaa tcataggggc tataaactct ccgtctactt
    21181 gtcctgcaac aattgaagtc tgctcaaaac gccgtccgct aatcttttca tagactttct
    21241 cccttttagg agcctagctt tctagtttgt tctttgattt ttattgagta taccactatt
    21301 ttactccctc tggcaaggga ctttgtctat gtggagggat tgggctccta tgtggtggag
    21361 cttttctgtt ctttctgaaa tatggtataa tagcactaat caatttctag gaaaatagat
    21421 acagaaaggg gctgaaagat gtctcatatt attgaattgc cagagatgct ggcaaaccaa
    21481 atcgcggctg gagaggtcat tgaacgtcct gccagtgtgg tcaaagagtt ggtagaaaat
    21541 gccattgacg cgggctctag tcagattatc attgagattg aggaagctgg tctcaagaag
    21601 gttcaaatca cggataacgg tcatggaatt gcccacgatg aggtggagtt ggccctgcgt
    21661 cgccatgcga ccagtaagat aaaaaatcaa gcagatctct ttcggattcg gacgcttggt
    21721 tttcgtggtg aagccttgcc ttctattgcg tctgttagtg tcttgactct gttaacggcg
    21781 gtggatggtg ctagtcatgg aaccaagtta gtcgcgcgtg ggggtgaagt tgaggaagtc
    21841 atcccagcga ctagtcctgt gggaaccaag gtttgtgtgg aggatctctt tttcaacacg
    21901 cctgcccgtc tcaagtatat gaagagccag caagcggagt tgtctcatat cattgatatt
    21961 gtcaaccgtc tgggcttggc ccatcctgag atttctttta gcttgattag tgatggcaag
    22021 gaaatgacgc ggacagcagg gactggtcaa ttgcgccaag caatcgcagg gatttacggt
    22081 ttggtcagtg ccaagaagat gattgaaatt gagaactctg acctagattt cgaaatttca
    22141 ggttttgtgt ccttgcctga gttgactcgg gctaaccgca attatatcag cctcttcatc
    22201 aatggccgtt atattaagaa cttcctgctc aatcgtgcta ttttggatgg ttttggaagc
    22261 aagcttatgg ttggacgttt tccactggct gtcattcaca tccatatcga cccttatcta
    22321 gcggatgtca atgtgcatcc aactaagcaa gaggtgcgga tttccaagga aaaagaactg
    22381 atgactctgg tttcagaagc tattgcaaat agtctcaagg aacaaacctt gattccagat
    22441 gccttggaaa atcttgccaa atcgaccgtg cgcaatcgtg agaaggtgga gcaaactatt
    22501 ctcccactca aagaaaatac gctctactat gagaaaactg agccgtcaag acctagtcaa
    22561 actgaagtag ctgattatca ggtagaattg actgatgaag ggcaggattt gaccctgttt
    22621 gccaaggaaa ccttggaccg attgaccaag ccagcaaaac tgcattttgc agagagaaag
    22681 cctgctaact acgaccagct agaccatcca gagttagatc ttgctagcat cgataaggct
    22741 tatgacaaac tggagcgaga agaagcatcc agcttcccag agttggagtt tttcggacaa
    22801 atgcacggga cttatctctt tgcccaaggg cgagatggac tttacatcat agatcagcac
    22861 gctgctcagg aacgggtcaa gtacgaggag taccgtgaaa gcattggcaa tgttgaccag
    22921 agccagcagc aactcctagt gccctatatc tttgaatttc ctgcggatga tgccctgcgt
    22981 ctcaaggaaa gaatgcctct cttagaggaa gtgggcgtct ttctagcaga gtacggagaa
    23041 aatcaattta ttctacgtga acatcctatt tggatggcag aagaagagat tgaatcaggc
    23101 atctatgaga tgtgcgacat gctccttttg accaaggaag tttctatcaa gaaataccga
    23161 gcagagctgg ctatcatgat gtcttgcaag cgatctatca aggccaatca tcgtattgat
    23221 gatcattcag ctagacaact cctctatcag ctttctcaat gtgacaatcc ctataactgt
    23281 cctcacggac gtcctgtttt ggtgcatttt accaagtcgg atatggaaaa gatgttccga
    23341 cgtattcagg aaaatcacac cagtctccgt gagttgggga aatattaaaa gtataaaaaa
    23401 gtctgggaaa aattttcaaa atcagaaaaa cgcataaaat caggtgttca aaaaccttga
    23461 ttttatgcgt tttatcatag aaatatttac ttcatttttt cctaattctt ttcgaaactc
    23521 tttttaaacc acgtcagttt tatcagtaat ctcaaaacag tgttttgagc taattttgcc
    23581 agttttgtct gtaacatcga agttgtgttt taccactctg cgactggttt cctagtttgc
    23641 tctatgattt tcacagagta ttaaattgcg attttgccaa gtttctttat tcgtctaaaa
    23701 gtagagtctg ttctatgcgt ctaatgtacg aattaggttg accatttcaa tagctccttg
    23761 tgcacactca gaacccttat ttcctgcttt agtaccagct cgttctatgg cttgttcaat
    23821 tgtatctgtc gttaacacac caaacataac aggaatttcg ctatttaaac tgatttgggc
    23881 gattccctta gatacctcgc tacatacata atcataatga cttgtattcc ctctaatgac
    23941 agctcccaag cagataattg catcatattt tttacttttt gccatttttg atgcaatcag
    24001 tggtatttca aaagctcctg gaacccaggc tacctcgata tctttctcgt ttacattctc
    24061 tcttttgaga ttatctagtg ctccagataa taattttgaa gttataaatt cattaaatct
    24121 cgctacaaca atacctattt taatattgtt tgctactaaa ttaccttcat aagtgttcat
    24181 ttatttttcc tccatattta aaatgtgacc cattcgattt ttctttgttt ctaaataaaa
    24241 actatcgtaa ggattggctt ctatttcgat tgatattcta ctggaaatgg taattccata
    24301 tttttctaac tgttcaacct tgtcaggatt atttgtcagt aaatgaagtg actgaagtcc
    24361 cagatcttta agcatttgtg ctccaatatg atattctctt aaatcacctt caaagcctaa
    24421 tgcaagattg gcatcaagcg tatccatgcc ttgatcttgt aaatgatagg cttttaattt
    24481 attgataagt ccaattcctc gtccctcctg tcgcaagtaa agtaagacac ccgaaccatt
    24541 ctcaacaatc attttcatag ctttatcgaa ttgctgtcca caatcgcaac gtaaagagcc
    24601 taaaacatct cctgttaaac attcggagtg gacccgacat aatacattgg cttcatcctc
    24661 tatgtttccc ataataagag caagatgatg ttccccattt agtttatcta tatagctaat
    24721 tgctttgaaa ttaccgtatc tagtaggcat attgacagtt gaaactcgtt ctaccagctg
    24781 atcatatact tttctatatt cttgtaattc tttgatggta attagtggaa tgttgtgttt
    24841 cttcgagaac tgaattaaat catctgttct catcattttg ccatcatgat tcattatttc
    24901 acaacatagg ccacactctt ttagtccagc taattttaat aaatcaacag ttgcttctgt
    24961 gtgtccattt ctttctagaa caccaccttt ttttgcaatt aaaggaaaca tgtgtcctgg
    25021 cctgcgaaaa tcagagggtg ttatatcttc agctacacac atacgtgcgg tcagtcctct
    25081 ttcctcggca gaaatacctg tggtcgtttc tttataatca attgaaactg taaaagcagt
    25141 cttatgatta tctgtattgt tttcaaccat aggtgaaagc attaattgat tagctaaact
    25201 ttcgctcata ggcatacaaa ttaatccttt ggcataagta gccataaaat taacattttc
    25261 tgttgtagct gcttgtgcag aacaaattaa gtctccttca ttttctctat ccttgtcgtc
    25321 tataacaaga acaagtcgtc ccttctgcaa tgcttctaat gcttcttgta tttttcgata
    25381 ttccattgac tgattatcct ttctgctaaa atccattttg atataatagt tccttagata
    25441 tttctgattt tggagagtta tccatcagtt tttgcacata tttacctaag atatcatttt
    25501 caagatttac tgtactcccg acttgtttac tcttaagaat ggtttgttcc aaggtatgag
    25561 ggataacaga tactgaaaag tttactttgg agactttagc gacagtcaga ctaatgccgt
    25621 caattgtaat agatcctttt tcaactatta aatctaaaat ttctttttgt gtgttgattt
    25681 gataccatac agcattatca tcttttttta ttgacgagat ttttcctgta ccatcaatgt
    25741 gtcctgtaac gacgtgaccc ccaagtcgac cgttgacaga taaggctctt tctagattca
    25801 cctcacttcc atgttttaat agagtaagag ctgttcgact ccatgtttca ttcattacat
    25861 caactgtaaa ggattgatga ttgaaatgag taactgtaag acagatacca tttactgcta
    25921 tactatcgcc taaatggata tccgttaata tttttgaggc tttaattgat agtttacaat
    25981 tacgagagtc tttctgtatt ctttcaactt ttccgatttc ttcaattatt cctgtgaaca
    26041 tggataaatc acttcacttt ctatgagata gtcatttcct atttgagaaa aagcataagg
    26101 tttcaatcta atagcgtcat ttggcaaaga aatgccttca cctccgacag gaaacttggc
    26161 actgcctcca aaaatttttg gtgcaatata tattttcagc tcatcaacaa tttgttgttc
    26221 caaagcactc caattcatta gactgccccc ttctagaact aggctatcaa tctgcatgtt
    26281 tcctagatgt tgcattaaac tcgataagtc tatatgattg ccttttttct ttatggaaag
    26341 tatttcacag ccatgatttt gatatagctt cattttattt ttgtcttcag aggaagtggc
    26401 aatgtaagtt ttaatatcat ttgctgtttt tacgatttta gaggtaagag gagttcgtaa
    26461 atgtgtatcg catatgatac ggataggatt tttcccttcc tccaatctac atgtcagcaa
    26521 aggatcgtct tgaataacag tattgactcc caccataatt gcactaacat agtgtcgtaa
    26581 ctgatgcaca tgctttcttg cttcttcttc agtaatccat ttggattgat ttgttttagt
    26641 ggctattttt ccatccattg acattgcata tttcataaaa acatagggta catgctgggt
    26701 aatatacttt ctaaaacttt ttattaagtt aagacactca ttttctaaaa ttccaacagt
    26761 aacttgaaga ttattttcct caagtatctt tactcctttt ccagatacaa taggattaca
    26821 gtctaggctt ccaatgacta ctcttgtaat accactatcg attatagcat ctatacaggg
    26881 aggtgttttc ccgaagtgac aacagggttc aagtgttaca taaagcgtcg ctccgacagg
    26941 ggattttcta cagtttttaa gagcatttct ctcagcatgt gggccaccaa aaaactcatg
    27001 ataaccttgt ccgataatgt gattatcttt tacaataact gcgccgacca taggattggg
    27061 attgacgtaa ccagcccctt tttgtgccag ttttattgct aatttcatat attttgaatc
    27121 gctcatctca ctacctccaa aaaaatatac cttgaatagg ggactactca aggcatacaa
    27181 aagaaaactt atgcgattaa caaaaatgct ctgaaatgac aagtaatcat ttcagagcac
    27241 gcaaaaagca caaatatact tttatcttct ttcatccaga ctatactgtc ggctttggaa
    27301 tttcaccaaa tcatgccttt cggctcgtgg gctataccac cggtagggaa ttgcaccctg
    27361 ccctgaagat agttattcaa ttacagatga ttatagtact taattttgaa tatgtcaaca
    27421 gataaatacc gattgttttt gatatactgt atttgtgata atcgattctc gctcctcgga
    27481 taaagaaaat atgatatact agataaacga aataagagag aaggaacact atgtacgcat
    27541 atttaaaagg aatcattacc aaaattactg ccaaatacat tgttcttgaa accaatggta
    27601 ttggttatat cctgcatgtg gccaatcctt atgcctattc aggtcaggtt aatcaggagg
    27661 ctcagattta tgtgcatcag gttgtgcgtg aggacgccca tttgctttat ggatttcgct
    27721 cagaggatga gaaaaagctc tttcttagtc tgatttcggt ctctgggatt ggtcctgtat
    27781 cagctcttgc tattatcgct gctgatgaca atgctggctt ggttcaagcc attgaaacca
    27841 agaacatcac ctacttgacc aagttcccta aaattggcaa gaaaacagcc cagcagatgg
    27901 tgctggactt ggaaggcaag gtagtagttg caggagatga ccttcctgcc aaggtcgcag
    27961 tgcaagcaag tgctgaaaac caagaattgg aagaagctat ggaagccatg ttggctctgg
    28021 gctacaaggc aacagagctc aagaaaatca agaaattctt tgaaggaacg acagatacag
    28081 ctgagaacta tatcaagtcg gcccttaaaa tgttggtcaa ataggagcag agaatgacaa
    28141 aacgttgttc gtgggtcaag atgaccaacc cgctctacat cacctatcat gatgaggagt
    28201 ggggccagcc cctccatgat gaccaagcat tgtttgagtt gttgtgtatg gaaacctatc
    28261 aggcaggcct gtcttgggaa acggtactca acaaacgcca agctttccga gaagcctttc
    28321 atagctatca aattcactca gtcgcagaga tgactgacac tgaattggaa gccatgctgg
    28381 agaatccagc tatcattcga aatagagcca agatttttgc tacacgcgct aacgcccaag
    28441 cctttctaca gttacaggca gagtacggct cttttgatgc ctatctttgg tcttttgttg
    28501 aggggaaaac tgtcgttaac gatgttcctg attatcgcca agccccagct aaaacaccct
    28561 tatctgagaa attagccaaa gatctcaaaa aacgaggctt caagttcaca ggcccagtcg
    28621 ccgtattgtc ttttctacag gctgcagggc tagttgatga ccacgagaat gattgtgagt
    28681 ggaaaggtct taaatgatgt ctaacaaaaa taagggaatt ctgatttttg cgattctcta
    28741 tacagtcctc tttgtgtttg atggcgttaa attgctggct tctttaatgc catctgccat
    28801 tgcaaattat cttgtttatg tagttttagc tttatatggc tccttcttgt tcaaggatag
    28861 attgatccaa caatggaagg agattagaaa gactaaaaga aaattcttct ttggagtctt
    28921 aacaggatgg ctctttctca ttctgatgac tgttgtcttt gaatttgtat cagagatgtt
    28981 gaagcagttt gtgggactag atggacaagg tctaaatcag tctaatattc aaagtacctt
    29041 tcaagaacaa ccactactga tagctgtttt tgcttgtgtc attggacctc tggtagaaga
    29101 attatttttc cgtcaggtct tattgcatta cttgcaggaa cggttgtcag gtttactaag
    29161 cattattctg gtaggacttg tttttgctct gattcatatg cacagtttgg ctctatcaga
    29221 gtggattggt gcagttggtt acttaggtgg aggccttgcc ttttctatta tttatgtgaa
    29281 agaaaaagag aatatctact atcccctact tgttcacatg ttaagcaaca gcctctcctt
    29341 aatcatttta gctatcagta tagtaaaatg aaatgagaac aggacaaatc gatttctaac
    29401 aatgttttag aagtagaggt gtactattct agtttcaata tactgtaata tgtgatgaaa
    29461 atgccagtaa tgataccgag aaaaaagctg agaaactttt cccagcttta tttgttatag
    29521 tcaaagagaa tgacttgttc ctgtgcatct acatgagcat ggaccccaaa gggtacaatt
    29581 gctcttggag ttgcgtggcc gacattcaga ttatagacaa tcgggatatt gctgtcaatg
    29641 atatccaata gtgcctcttt atagtcgtca tggaaagttt catccatagg ttttccgacc
    29701 aagagtccat tgatgaccgc gaatatgcca gtgtccttta aagttagcaa catctttttg
    29761 aagtcttctg gcttaggctt ttcttcgctt gtttcgagca agaggatttt cccttcccag
    29821 tctgacaagt cagggaaaag tttgtatttt tggcagagtt ccgtgctatc tgcgtatcga
    29881 gagttgtcaa agatatcgta gagggattcg aggcaaccac cgaggatttt cccctcgaac
    29941 tgggcacttc cttgcaacaa gtcaaaacct gtatttgtat gactgacacg aggtgttccc
    30001 agggccgtgg gactaaaatc agttcgttcc tcataccaaa cgtcactagg gcggatttct
    30061 gaaattcttc ccgtctcaat caattcttta aagtagtgaa ggctataggc tagcatttct
    30121 ttgtctaatt cacaaatgtc tgctaaaaag gattgaccat aaaaagtctt gattcctaat
    30181 ttatgcaaca tgaggtggtt catggttgta tccgagaagc caagaaaaat tttttgtttg
    30241 ataccctttt ggagttggtc attttcaaaa agataaggta gcaagcgata ggcatcgtct
    30301 ccaccgatgg cacataggat catgtcgatc tatcatcaga aaaggcatga atcaaatcct
    30361 ctgcacgagc ttcaggatgg tccttgataa agtctaatcc ttttaacgaa tggggcaaaa
    30421 agatgggatt gagtcccaga tccttgagac gttggatacc caagtccact tcgtgtttga
    30481 caaaatcctc tccgataatg ccactagata aactaacaat accaatagta gaaaccatat
    30541 ctcatcctcc tagaaataga ttgagcctat tttatcacaa aatataagag aaagctatgt
    30601 gggatttcag aagaatactt ttaatactct tcgaaaatct cttcaaacca cgtcagtttt
    30661 atttgcaacc tcaaagctgt gctttgagca acctgcagct agcttcctag tttgctcttt
    30721 gattttcatt gagtataact caaaaaagta agtgaaaaag caaccgcacc tgcagttgct
    30781 tttatcgttt tcttattctt gatagcgtgt tggtcctgca cttgcactac ggatattcaa
    30841 gcgtttcttg agatagaagc gaagggctag gagggctgct ccaataatag ctagtggcaa
    30901 tggatccagt actgggttaa ggctagctgg taggaagctt gttgcaaaga agacaagcaa
    30961 ccaaaggaac atagaagcta ggataactag tacagatttc cagaaaggtg gacgttgact
    31021 gcgatccata tctggtccat agtattggta aacaaagtag tacatcaagt agaaggcaaa
    31081 tccaccaacc agtccaacta atagaagagt aatcaatcca tagccgaaag cttgatctgc
    31141 cgcaaagaag gttgtgaggg cgctgacaag ggcaaagagg ctagtgatga aaagagctga
    31201 gtccataatc atcagttttg gatcatcatt ttcttttgga tgctcttttt cgtactgctc
    31261 tttgacagtg aagctatgag cccaatgagt tggtgcgccg tatagggaac gggcagttgt
    31321 acctttagat tgctcctcaa ggatttgggg aatgacttcc tcaaaaatag tctggatttc
    31381 agcgtctgtt ttcccatctt tgatgaattg ttgggtagca atgtggacaa actcttggtt
    31441 tttcttagtt aatttttgta gatcaatttg agacatagga actcctctta gaaccatttt
    31501 ttatggatga gatagagagt gagcgagaca ctcatagcaa aggcgataaa gacgattaac
    31561 cagaaggcat ttggctctcc gtttaggggg atttcattat ccttaaagtt catcccgtag
    31621 gcagaaaaga ccatggttgg gatggacatg acgatggtca caagggccaa ggttttcatg
    31681 atgttgttct ggttgttaga aatgatagag gcaaaggtct ctgtcataga atgcaagacg
    31741 tttccataaa tatctgccat ctcgatggcc tgttgggttt caatcagggt gtcttcaagc
    31801 aggtcttcgt cttcaaggta tttcttgata ttgctggttg aactggtcaa tttcttaatc
    31861 acgcgctcat ttgttttgag ggaggccttg aaatagacga tagttttttc caattccatg
    31921 agctcaatca attcttcatt acgagttgat tgatgcagtt gactttcgat ttgttcactc
    31981 ttgcggtcga ttgaacgaag ggctgttagg taaagctctg cattgcgata aagaatttga
    32041 aagataaaac gtgaacgcat gaaggtatag aaattacgca atcgacggtt gataaagaca
    32101 tcaaggacag gtagtggttc caaacacgta gtgataatgg tttcctcagt gatgataata
    32161 ccaagcggga tggttacgta gtaggtgcgg ttatttcttt cctccgtgac cggcacgtct
    32221 acgataatca gggtatactc gtcttcaatg gtaatacgag acatttcttc cgcatcgagc
    32281 ggtgctcgaa ggtcggcaat atcaatatcg aaggtgttgg cgatttcgag tgattcattt
    32341 tgagtcggat tgacgagatt gatccaagta cccggttcaa gcgtatcgat ctctttaaat
    32401 tcagttgttg tagagagaaa aacttgtttc atatccctta tcctttctca tttttcagat
    32461 tttttcacac tgtactatta tactacaaaa tcggcctttt gggtaataga atctcacttt
    32521 ttttggtata atggtaagca ataatggact agaaagaaca aagatgcaag ataaaattgt
    32581 cattcatggg gcgcgtgccc ataatttaaa aaatattgat gtggagattc cgcgagacaa
    32641 gttggttgtc gtgactggct tgtcaggttc agggaagtcc agtctggctt ttgataccct
    32701 ctatgcggag ggacaacgtc gctatgtaga gagtttgtcc gcctacgctc gtcagttctt
    32761 gggaaatatg gaaaaaccag atgtagatgc cattgatggt ctcagtccag ctatttctat
    32821 cgaccagaaa acgactagca aaaaccctcg ctcgacggtg ggaacaacga ctgaaatcaa
    32881 tgactatctg cgtctcctct acgcacgtgt ggggacgcct tactgtatca acggacatgg
    32941 agctatcaat gcttcttctg tggagcaaat cgttgataag gttttggagt tacctgaacg
    33001 ccagcgcttg cagatcttgg cctctgtcat ccgcaagaaa aaaggccaac ataagagtgt
    33061 tatcgagaag gttcagaaag acgggtatgt tcgtgtccgt gtggatgggg aagtctatga
    33121 tgtgaccgaa gtgccagagt tgtctaagag caagcaacac aatatcgatg tcgtggttga
    33181 ccgtattgtt atcaaggagg gcattcgtag tcgtctcttt gattccattg aggctgccct
    33241 tcgtattgca gaaggttatg tcattatcga caccatggac gactctgagt tgttgttctc
    33301 tgagcattat gcctgtccag tttgtggttt tactgtccca gagttagagc ctcgtctctt
    33361 ctctttcaat gctccttttg gctcttgtag tgagtgtgac ggcttgggca tcaagctgga
    33421 ggtggatact gatttggtag tgccagatgc cagcaaaacc ttacgtgagg gagcgttagc
    33481 accttggaat cctatctcat ccaactacta tccaaacatg ttagagcagg ccatgaaagt
    33541 atttggagtg gctatggata agccttttga ggacctgtca gaagaagata agaacttgat
    33601 tctctatggg tcagatggta aggaattcca tttccactat gagaatgaat ttggtggcgt
    33661 gcgcgatatc gacattccgt ttgagggagt tatcaataat atcaaacgtc gttaccatga
    33721 aaccaatagc gattacactc gcactcagat gcgtctctac atgaatgagc tgacctgcgg
    33781 aacctgtcaa ggctatcgtc tcaatgacca ggccttgtct gtccgtgtgg gcggccagca
    33841 agggccacat attggagaaa tctcagacct gtctatcgct gaccacttgg acttggtgag
    33901 ccagttaact ttgtctgaaa atgaagccat cattgctcgt cccattctca aggaaatcaa
    33961 ggatcgtttg accttcctta ataatgtggg tcttaactat ctaaccctgt cacgttcagc
    34021 aggaaccctt tcaggtgggg aaagtcagcg cattcgtttg gcaacccaga ttggttccaa
    34081 cctatcaggc gtcctctata tcctagacga gccgtcaatc ggtcttcacc agagagacaa
    34141 tgaccgcctg attgccagtc tgaaaaagat gcgtgacttg ggcaatactc ttatcgtggt
    34201 ggaacacgac gaagatacca tgcgtgaagc tgattatctg attgacgttg gtcctggtgc
    34261 cggtgttttt ggtggtgaga ttgttgcagc aggtacacct aagcaagtgg ctcgcaacag
    34321 caagtctatc acaggtcagt acttgtcagg caaacgtgtc atcccagtac cagaagagcg
    34381 ccgtgtcgga aatggtcgtt ttattgaagt gataggagcg cgtgagaaca acttgcaaaa
    34441 tgtcacggct cgctttccac taggaaaatt tatcgcagtg acaggtgtgt cgggttcagg
    34501 gaaatcgact ctaatcaaca gcattctcaa aaaagccatt gcccagaagc tcaaccgtaa
    34561 ttcagacaaa cctggtaagt ttaagactat tacagggatt gagcatgtcg accgtttgat
    34621 tgatattgac cagagcccta tcggacggac gccgaggtct aacccagcta cctatacagg
    34681 agtttttgac gatatacgtg acctttttgc tcagacaaat gaagccaaga ttcgaggcta
    34741 caagaagggg cgcttcagtt tcaacgtcaa gggaggtcgc tgtgaagctt gctcaggtga
    34801 cgggattatc aagattgaga tgcacttctt gccagatgtt tatgtggctt gtgaagtttg
    34861 ccacggaacc cgctataaca gtgaaaccct agaagttcac tacaaggaaa agaatatttc
    34921 gcaggtcttg gatatgacgg tcaacgatgc ggtagaattt ttccaacaca ttccgaaaat
    34981 tcaacgcaaa ctccagacca tcaaggatgt agggctaggc tatgtgacct tgggacagcc
    35041 agctaccacc ctttctgggg gagaagccca acgtatgaag ttagctagcg aactccacaa
    35101 acgctcgaca ggaaaatctt tctacattct ggatgagccg acgacagggc ttcatacaga
    35161 ggacattgct cgcctgctca aggttttagc tcgctttgta gacgatggca atacagtcct
    35221 cgtcatcgag cacaatctgg atgttatcaa gacggcagac catatcattg acttgggacc
    35281 tgagggcggt gtcggtggtg gaaccatcat cgtaacagga actccagaag aagtagctgc
    35341 caatgaagcc agctatacag gacactattt gaaaggaaag ttacatcatg aataaacgcg
    35401 tacaagcatt tctagctaaa atgcaagaaa aagaactaga tggtatcatc atcaacaatc
    35461 ttaaaaacgt ctattatttg actggttttt ggggctcaaa cggaacagtc tttatcagcc
    35521 gtgaccgtca ggtcttagtg acagactctc gctatatcat cgcagctaag caagaaacca
    35581 gtggttttga gattgtggct gatcgtgatg aattggctgt cattgcagga attgttaagg
    35641 acatgggctt gactcgtatc ggttttgaag atgagatttc agtatcttat taccaccgta
    35701 tgcaggcagc ttttgcaggt ttggacttgc ttccacaaac tcaatttgtg gaaggtcttc
    35761 gtatgattaa ggatgaggca gagattgcag cgattcgcaa ggcttgttct atctcagacc
    35821 aagctttccg cgatgcgctt gactttatca aaccaggaaa aactgaaatt gaaattgcca
    35881 acttccttga tttccgcatg cgtgagttgg gagcatctag cttatctttt gatacgatcc
    35941 tagctagcgg tatcaattct tctaaacccc atgcccatcc aatgcacaaa ccagtggagt
    36001 tgggagaagc cattaccatg gacttcggct gtctctatga ccactatgtc agtgatatga
    36061 cccggactat ctatctaggg catgttagcg atgagcaggc agagatttac aatacggttc
    36121 taaaagctaa ccaagccttg attgaccaag ctaaggcagg cttaggtttc cgtgactttg
    36181 acaaaatccc tcgtgatatt atcattgagg caggttatgg cgactacttt actcacggca
    36241 ttggccacgg tattggtctg gatatccatg aggaacccta ctttagccag acttctacag
    36301 aaactattaa gacaggtatg gccttgaccg atgaaccagg tatctatatc gaaggcaaat
    36361 atggcgttcg tatcgaggat gatatcctga ttacagagac aggttgtgaa ttattgaccc
    36421 tagctccaaa agagttgata gtcatttagt tgtttgtcaa gaaaaaagta cgaaaatgac
    36481 gaaaaaagtc aaaaaaaatt aaaaataggt cgcaagtcgg atgtttttta tggtataata
    36541 gactaaactg atagtaacat gtagcgaaag gggtaggtac atgattaaaa tttatacagt
    36601 ctcaagttgt actagctgta aaaaagcaaa aacctggctc aatgcccacc agttaagtta
    36661 taaagaacaa aaccttggta aagaaggaat tacgagagaa gaattactgg atattctaac
    36721 caaaacagat aacggaatag ccagcatcgt ttcgtctaaa aatcgctatg ccaaagccct
    36781 tggagtggat attgaagatt tgagtgtcaa tgaagttctc aatctgatta tggaaacacc
    36841 gagaatttta aagagcccaa tccttgtaga tgaaaaacgc ctgcaagttg gctacaagga
    36901 agacgatatt cgtgccttcc taccacgctc tgtccgtaat gtagaaaatg cagaagcacg
    36961 tttacgtgca gctctataaa catcaaggct gggagcactt cccagtctta ttctatttta
    37021 atttcaaaaa gaaagaagag agaaatgaaa aaaatagttc ttgttagtct agctttcctt
    37081 tttgtcctgg ttggttgcgg acagaaaaaa gaaactggaa cagctacaaa aacagaaaag
    37141 gatacgcttc agtcggcatt gccagttatt gaaaatgccg agaagaatac agttgtaacc
    37201 aagactttgg tcttgcccaa gtcagatgat ggtagccagc aaactcaaac cattacatac
    37261 aaggacaaga cttttttgag cttaacgatt caacaaaaac gtccagtttc tgatgagttg
    37321 aagacttata tcgaccaaca tggagtggaa gaaactcaaa aagctcttct tgaagcggag
    37381 gagaaggata agtctatcat tgaagctcgt aaattggcag gtttcaaact tgaaacaaaa
    37441 ctattgagcg caacggaact tcaaacaacg actagttttg attttcaagt tctggatgtc
    37501 aagaaggctt cccagttgga acatctgaag aatattggtt tggaaaatct tttgaaaaat
    37561 gaaccaagca aatatatttc agatagattg gcaaatggcg cgacagaaca atagaaaatc
    37621 caaataaata gactgcctga attgtagaag gtaaggaatt atgctataat ggtactattc
    37681 taaggaaaga gggtgttaga atgggattta ctgaagaaac agtacgtttt aaattggacg
    37741 attccaataa aaaagaaatt agcgaaactt tgacagatgt ttatgcttcg ttgaacgata
    37801 agggttacaa cccaattaac caaatcgtag gttacgtatt gagtggagac cctgcctacg
    37861 ttcctcgtta taataatgca cgaaatcaaa tccgtaagta tgagcgtgat gaaatcgttg
    37921 aggaattggt tcgttactac ctcaaaggac aaggagtcga tctataacct atgagaatta
    37981 tgggattgga cgtcggttca aaaacggtag gggtggcgat tagcgatccg cttggtttta
    38041 cagctcaagg gcttgaaatc atccagataa atgaagaaca aggccaattt ggttttgacc
    38101 gcgttaagga attggttgat acttacaagg tagaacgatt tgtagtgggc ttgcctaaaa
    38161 acatgaacaa tacaagtgga ccgcgcgtag aagctagtca agcctacgga gcaaagctag
    38221 aagagttttt tggtttacca gtagactatc aggatgaacg cttgacaaca gtggctgctg
    38281 agcgcatgtt gattgaacaa gcagatatca gtcgcaataa gcgcaagaaa gtcattgata
    38341 agttagcagc tcagctgatt ttacaaaatt atttagatag aaaattttaa tataaaggag
    38401 aggctatgtc acacgatcat aaccacgacc acgaagaacg tgaactaatc acactagtag
    38461 atgagcaagg aaatgaaacc ttgtttgaaa tccttttgac aattgatgga aaagaagaat
    38521 ttggtaaaaa ctatgttctt ctagtaccag ttaacgcaga agaagacgaa gacggacaag
    38581 ttgaaatcca agcttactca ttcattgaaa atgaagatgg aacagaaggc gaattgcaac
    38641 caatcccaga agactcagaa gacgaatgga acatgattga agaagtcttc aacagcttta
    38701 tggaggagtg atacagtctg ggagactgta tcagcccaac tcccagaaat ggggaagagt
    38761 tggaacgtcc agtgaacatt tttaccccaa ctcttagaac ttgagaagag ttggaacatc
    38821 tagtggatgt ttttagccca tattcacatt catagtagct agttattagc taaccaggta
    38881 agaggtcggg acgaaaatcc tggccttgtt tttattagta accatacttt aatgcgataa
    38941 ttgattggac ttttgtcaag gagatgtgta tgtttgaagt agaagaatgg ctccatagtc
    39001 ggattggttt gaattttcga tcaggtttgg gccgaatgca gcaagcggtg gatttgttag
    39061 gaaatcctga gcagtcttac cctattatcc acgtaacagg gactaatggg aaaggatcta
    39121 ccattgcttt tatgagggaa ttatttatgg ggcatggcaa aaaagttgcg acctttacct
    39181 cccctcatat cgtctctatc aatgaccgaa tctgcattaa tgggcaacct atagcagacg
    39241 cagactttat ccgtttgact gatcaggtca aagagatgga gaaaacgctt ctgcaaactc
    39301 ctgcccagtt gtcctttttt gaattgctga ccttagttgc ttttctttat tttagggagc
    39361 aggaggtgga tttggtttta ttagaagtgg gaattggtgg cttacttgac acgaccaatg
    39421 tggtaactgg agagcttgct gtcatcacct ccattgggct tgaccatcaa gaaaccttgg
    39481 gtgatagtct agaagcaatt gcagagcaga aagctggtat tttcaaggat ggtaagaagg
    39541 cagtgattgc gaaattgcct ccagaagcta ggcttgtctg tcagaaaaaa gccgaatctt
    39601 tagctgttaa cctttatcag gcaggtcaag attttttaat gctgaatggt gatttttcaa
    39661 gctctttact aaatctttca cagctgaaca taggcttaga aggagtctat cagcaggaga
    39721 atgcagcctt ggcgttgcaa acttttcttc tttttatgag agaaggaaag gaagctgttg
    39781 atgaacaggc tgtaagaaag gccttggaac agacccattg ggctggtcgc ttggagcgta
    39841 ttcgcccaca gatttacttg gatggtgctc ataacctccc tgccttgact cgcttggttg
    39901 agtttatcaa agaaaaagag caggaaggct atcgacctca aatcctcttt ggatccttga
    39961 aacggaagga ttatcaaggg atgttgggtt atctgactga aaatttacct caagtggaac
    40021 tcaaaatgac cggctttgac tatcaagggt ctttggacga gacagatgtc acaggttacc
    40081 atgtaattcc ctcttaccga gaatttatca gcagtttcga agaaagggca gacgctcaag
    40141 acttgctgtt cgttacaggg tctctctatt ttatctcaga agtacggggc tacctgctgg
    40201 accgtgagca gataaattga cccccttgtt tgaacttgtt atactagggg aattgctggt
    40261 tagagaaaat ttctctaaat tggtagcaga aaggaaattc atcatgaaat taaaaagatt
    40321 cacactttct cttgcttctc tagcaagttt tagtctctta gtagcttgtt cacaaagagc
    40381 tcaacaggtt caacagcctg ttgctcagca ggtccaacag cctgctcaac agaataccaa
    40441 tactgcaaat gcaggaggta accaaaatca agcggctcca gtacaaaacc aacctgttgc
    40501 tcaaccgacc gatattgatg ggacttatac tggtcaggat gacggagacc gtatcacttt
    40561 agtggtaact ggaacgactg gtacatggac tgagctcgaa tctgacgggg atcagaaagt
    40621 caaacaggtt acatttgatt cagcaaatca acgcatgatt attggcgatg atgtcaaaat
    40681 ttacactgta aacggtaatc aaatcgtcgt agatgatatg gatagagacc catcggacca
    40741 aatcgtttta actaaataag actatgcaag tagaaagggc tggatttttc agccttttta
    40801 cttttaccta gaaaataatc ataaatactt gccttctacc gaatacctgc gttatactag
    40861 tatcaattac ttgtttttag cattcaaact atcaaggagg ggatatgaaa tataggaaat
    40921 ttcaattatt gatgtccaag tatggcttta gtctttcgat tatgctactt gaactttgtc
    40981 ttgtttttgg tctctttctt tatttaggac gcatggctcc cattttatgg attactgtcc
    41041 tcattctact gagtatcatc acaatcattt cgatagtcaa ccgtaatacg actcctgaga
    41101 ataaggtaac ctggttgtta gtagcctttg tgccagtatt tggtcccttg ctctatctga
    41161 tgtttggtga aaggcgattg tccaaaaaag aaatcaaaca actgaagaag ctaggctcta
    41221 tgcatttcca agaagcaaat agccagctac taaaagagaa attaaaagaa agtgacaagg
    41281 cagcttatgg agtcatcaag tccttattga gtatggatac caatgctgac atctatgatc
    41341 aaactgcctc tacatttttt cctaacggag aagctatgtg gaaaaagatg gtagaagatc
    41401 ttaaaaaggc tgagaaattt attttcttgg aatattacat tatagaagaa ggtttgatgt
    41461 ggaatcgcat actagatata ctagagcaaa aggtagctca gggtgtagag gttaagatgc
    41521 tctatgatga tatcggctgt atggctactt taacaggaga ttatgcacat cgacttcgtc
    41581 agctgggcat cgaggcccat aaattcaata aagttattcc tcgtttgaca gtggcttata
    41641 ataacagaga tcatagaaaa atattgattg ttgatggtca gatagcctat actggtgggg
    41701 tcaatctggc agatgagtac attaaccacg tcgagagatt tggttattgg aaggatagtg
    41761 gaattcgctt agacggacta gcagtaaaag ccctgacacg cttatttttg accacttggt
    41821 acattaatcg aggagaaatt agtgattttg atcaatatca tttagaaaat cattctatcc
    41881 cgagtgacgg tttaaccatt ccatacggaa gtggacccaa gccaattttt cgagcgcagg
    41941 tagggaaaaa agtttatcag agtttaatca atcaagcaac ggaatcggtc tatattacga
    42001 caccttattt gattatagat tatgatttaa cagagacaat caaaaatgca gctatgagag
    42061 gggtcgatgt tcgaattatc accccttaca taccagataa gaagttcatt cagttagtca
    42121 cgagaggggc ttatcccgac cttctttctg ctggtgttcg gatttatgag tatagtccag
    42181 gttttattca tagtaagcag atgttggtag acgaagattt tgcggtggtg gggacaatca
    42241 atctcgacta ccggagcttg gtacaccatt atgaaaatgc agtcttactc tataaaactc
    42301 cttctataat ggaaatcgcc cgagattttc gaaatatatt tgcagattct caggaagtct
    42361 atcctcattc tatcaaaacg agctggtatc aaaagcttgt aaaagaaatc gcccagctat
    42421 tcgcccctat cttataagaa atctagaact taggatacaa accagaccta tttttcttgt
    42481 cttttacgaa tagaaagaaa gaggagggga attcatgcta actaaggaag aagtgaatga
    42541 tatgattgag ttcaaacaga cacatttaca ccgctttcgg gaaattgaaa cctttgtgaa
    42601 actatgcaaa aaatcactca aacagccatc gcaagctgac aatcctagga ctttttgata
    42661 tactaagaca gataaattga acaggagaaa cgatatgagt gtgtatggta gagtagaaga
    42721 agttcataag gagaatcgtg aacctctaga ataccaaatc gaacaagaat cgcatcatcg
    42781 tgaatcaagt cgtcttcctt tggtgaaaat tttactatgg agtacgcttg taacggggat
    42841 aactctagga gtaccgctat tactcgactt aatgagtgca caagaagtgc aggattttta
    42901 tgcaggttgg gcgcttcatc agacagggaa gatttacagc gactattatg gaagtcaagg
    42961 tttgctttat tatttgctga cttacgtgag tcagggcgga tatttctttg ccatctttga
    43021 gtggttagcc ttggtagcag gaggattttt cctttttaga tcagcggaca ccttgacaga
    43081 gcaaggagac caagctggac atctggtgac tattttttac atgctagtta caggtcttgc
    43141 ttttggtgga ggctatgcga ctcttttagc gcttcctttc ttattcgcag cctttagttt
    43201 agttgcggct tacctaagca atccaagcca tgataaggga tttgtacgga ttgggctagc
    43261 tttggcaggc ggatttttct ttgctccctt atcatcgctc ctgtttattg ctgtagtgag
    43321 tttaggcttg ttggtcttta accttgggca tagacgtttt gtgcatgggt tttatcagtt
    43381 tcttgcagtg gctttaggtt tttcacttgt cttttatcca actgcctact atagtgctgc
    43441 aacaggaagt tttggggatg cgattagtgg tattcgttat cctattgaca gtattcgctt
    43501 tgattttact tctaaaattt tagagaatat gtttttttat ggcttgttgt cccttggttt
    43561 gggatttgtg gtttgtatct ttttaggtct ctttcaatcc aaacccttta aactatacgt
    43621 catttcggtt cctgcaagtc ttgtggtaat tttaggtttg attttacttt tcttttcaca
    43681 agagcctctg cacgcttctt atttgatggt cgtcttccct gttttcctac ttttattggt
    43741 aaccaatatt aagagtcaac agagggggcg tagtgctaga agaagccgaa gagaaacgcc
    43801 agttagccta tggagtcgtt tcttcaaagg aaatctatat ctgctagttt ttgggtttgt
    43861 ctatcttttg tctgttcctt ttttgatgaa gtttgtcctt tatccagtac cttatcaaga
    43921 acgtaatcgt cttgctgatt tggtaaaaga ggagacaaat acggaagatg ctatctatgc
    43981 atgggatgat actgcgactc tttatcgtaa gagtgagcgc ttgtcgccat cggcgatttt
    44041 gtacccgttg cactatacag caactgaaga aaatcgtaat aagttactta atgacttgaa
    44101 agaaaaacaa cctaaggtga ttgtggtaaa tgacaaggtg gtagtctggt ctgaagtgga
    44161 aacactctta aaagaaaatt accaacaagt aaagactgat tactcagagt ttaaagtcta
    44221 taaaattaaa taaccaaatc aatatcttgt gtatttttaa aaattttagg atttttaaca
    44281 caagatattg atttttcttt ttagagtggt ataatacttt ttagaaagaa cattttagaa
    44341 aagagcatgc atatgattgc actagaagaa aaaattacaa ttttgccaac tctcttcgtc
    44401 gagaaacgag atgggagacg tgttgtattt gatgtggaca agattgacaa ggctctccac
    44461 aaggcggctg acaaggttat ggatgtgaca cccctggttg aaaaacgcct caatgatctg
    44521 actgagcgaa ttattacaga aattcatagt cgctttccac agggaattaa gatttacgaa
    44581 attcaaaata tcgtagaaca tgaactcctt gaagccaaag aatatgcact ggctgaggag
    44641 tatattactt atcggacaca gagggatttt gagcgctcaa aagcgacgga tatcaacttt
    44701 agtattcata aacttctcaa caaagaccag acagttgtca atgaaaatgc taataaagac
    44761 agtgatgtct ttaacactca gcgtgatttg acagcaggga ttgttgggaa atcaatcgga
    44821 ctgcaaatgc ttcctaagca cgtagccaat gcccaccaaa agggggatat ccactatcac
    44881 gatttggact acagtcccta tacccctatg accaactgct gtttgattga ttttaagggt
    44941 atgttggaaa atggttttaa gattggaaat gcagaggtag agagtcccaa gtctatccag
    45001 actgcgacag cacagatttc tcaaatcatt gccaacgttg cttctagcca gtacggtggc
    45061 tgttcagctg accgtatcga tgaaattttg gcgccttatg cagagaagaa ctatcaaaaa
    45121 catctcaaag atgcagaaga gtgggtattg cctgaaaaac gggaagatta cgcttggaag
    45181 aaaacgcaaa aggacatcta cgatgccatg caatctcttg agtatgaaat caatactctc
    45241 ttcacttcaa atggacaaac accttttact tcgctaggtt ttggtctggg aaccagtcgt
    45301 tttgaacgag aaattcaaaa agctatttta aacattcgca tcaagggtct tggttcagaa
    45361 caccgtacgg ctatctttcc taaacttatt ttcactctga aaagaggcct taatttagag
    45421 gaaggaactc ccaactacga catcaagcag ttggctcttg agtgtgcaac caaacggatg
    45481 tatccagatg ttttatctta cgataagatt gttgacttga caggatcctt caaggtgcct
    45541 atgggttgcc gttctttcct ccaaggatgg aaggatgaaa atggtgtaga agtcaattca
    45601 ggtcgcatga atctgggtgt tgtgacggtt aatctgcctc gtattgctct tgagtctgaa
    45661 ggtgatatga ataagttctg ggaaatcttc aacgagcgaa tgaatatcgc agaagatgct
    45721 cttgtttacc gtgtcgaacg cactaaagag gcgacaccag cgaatgctcc tatcctttat
    45781 cagtacggtg cttttggcca tcgtctaggt aaagaagaaa gtgttgacca gctctttaag
    45841 aatcgtcgtg cgaccgtttc gctgggctat atcggcttgt atgaagtagc gacagttttc
    45901 tttggtaaca gctgggaaag taatccagat gctaaggaat tcacgctaga catcattcac
    45961 gatatgaaac gccgtgtaga agagtggtca gaccaatatg gctaccattt ctctatctac
    46021 tcaacaccat ccgaaagtct gacagaccgt ttctgtcgac tagatataga caagtttggc
    46081 tctattcctg atatcacaga caaggaatac tacaccaact ctttccacta cgatgttcgt
    46141 aaaaatccaa caccgtttga aaaattggac tttgagaaag tctatccaga agcaggtgcg
    46201 tcaggtggtt tcatccatta ttgtgagtat ccagtccttc agcaaaatcc aaaggccttg
    46261 gaagctgtct gggattatgc ttatgaccgt gtaggctatc taggcaccaa tactccgatt
    46321 gaccgttgct acaagtgtga ctttgaaggg gattttgaac caactgagag agggtttgct
    46381 tgtccaaact gtggcaatag cgaccctaaa acagtagatg tggtgaagcg aacttgtggc
    46441 tacctaggta atcctcaagc aagaccgatg gtcaacgggc gtcacaagga aatcgctgcg
    46501 cgtgtcaaac atatgaatgg ttcaacgatt aaaatagctg ggcatcaagt aacagattag
    46561 aaagaaatga aatgggaaaa tatcaactag acgataaggg gtgcgcacaa gtgacccgtt
    46621 atcacgagaa acactctaaa ggtggagctg gtaagaaaga acgcttgctt agcttcagag
    46681 aacaattttt aaacaagaac aagaaaaaat aaaagtgaga gccagctctc gcttttctca
    46741 tagtgggagg taaggatgga attacgcaga ccaagattag cggataagaa agctgtttta
    46801 gatatgatga cagagtttga aaaatttcag tcgcctcacg acggcggttt ctgggataca
    46861 gagaactttg tgtatgaaga ctggttagaa agcaatcagg aacaggaaat ggggattaat
    46921 ctgcctgaag gatgggttcc tgcaattcag ttagtggctt tttctgagaa aggtcaagca
    46981 gttggatttc ttaatctccg gttgcgcctc agtaactttc tactagaaga aggtggccac
    47041 attggctact ccattcgtcc atctgaaaga ggcaagggtt atgcaaaaga gactctccgt
    47101 cagggcttgc aagttgctaa ggaaaagaac atcaagaaag ctctggtgac ctgtagcgtg
    47161 aataatcctg ctagcagagc agtcattcta gcaaatggtg gaatatttga ggatgctcgc
    47221 aatggagtcg agcgttattg gatagaggta gcgaatgaat aatccaaaac cacaagaatg
    47281 gaaaagcgag gaacttagtc aaggtcgtat cattgactac aaggccttta actttgtgga
    47341 cggcgaaggc gtgcgtaact ctctctatgt atcaggctgt atgtttcact gcgagggatg
    47401 ttataatgtt gcgacttggt cttttaatgc tggcattccc tatacagcag aattagaaga
    47461 gcagatcatg gcagatcttg ctcagcccta tgttcaaggt ttgactttgt tgggagggga
    47521 gccttttctt aatactggga ttctcttgcc acttgttaag cggattcgga aggaattgcc
    47581 agacaaggac atctggtcct ggaccggcta cacttgggaa gaaatgatgt tggaaactcc
    47641 agataaactg gaattcttgt cactgattga cattcttgtc gatggaagat atgatcgaac
    47701 taagagaaat cttatgctcc agtttcgagg ttcatctaac caacgaatta tcgatgtgca
    47761 aaaatcgctc aaaagtgggc aagtagtgat ttgggacaag ctcaatgacg gaaaagaaag
    47821 ctatgaacag gtgaagagag aatgaagaaa aaatgaagaa aaaagactta gtagaccaac
    47881 tagtctcaga gatcgagacg gggaaagtca ggacactggg aatatacggt catggagctt
    47941 caggtaaatc aacctttgca caggaattgt accaagcttt agattctact acagtaaacc
    48001 ccaattat
//
LOCUS       DAVHKZ010000012        46589 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000012 DAVHKZ010000000
VERSION     DAVHKZ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46589
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.012"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(612..1025)
                     /gene="ndk"
                     /locus_tag="VVO74_000840"
     CDS             complement(612..1025)
                     /gene="ndk"
                     /locus_tag="VVO74_000840"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU5694884.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(1136..4813)
                     /gene="rpoC"
                     /locus_tag="VVO74_000841"
     CDS             complement(1136..4813)
                     /gene="rpoC"
                     /locus_tag="VVO74_000841"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU5694885.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(4846..8457)
                     /gene="rpoB"
                     /locus_tag="VVO74_000842"
     CDS             complement(4846..8457)
                     /gene="rpoB"
                     /locus_tag="VVO74_000842"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU5694886.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            8873..8943
                     /locus_tag="VVO74_000843"
     tRNA            8873..8943
                     /locus_tag="VVO74_000843"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8905..8907,aa:Cys,seq:gca)
     gene            complement(9141..10472)
                     /locus_tag="VVO74_000844"
     CDS             complement(9141..10472)
                     /locus_tag="VVO74_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU5694887.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(10763..11587)
                     /gene="endA"
                     /locus_tag="VVO74_000845"
     CDS             complement(10763..11587)
                     /gene="endA"
                     /locus_tag="VVO74_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU5694888.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(11626..11814)
                     /locus_tag="VVO74_000846"
     CDS             complement(11626..11814)
                     /locus_tag="VVO74_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU5694889.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(11807..13090)
                     /gene="murA"
                     /locus_tag="VVO74_000847"
     CDS             complement(11807..13090)
                     /gene="murA"
                     /locus_tag="VVO74_000847"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU5694890.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(13114..13344)
                     /locus_tag="VVO74_000848"
     CDS             complement(13114..13344)
                     /locus_tag="VVO74_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU5694891.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(13402..14439)
                     /locus_tag="VVO74_000849"
     CDS             complement(13402..14439)
                     /locus_tag="VVO74_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU5694892.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     INDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(14423..14911)
                     /gene="coaD"
                     /locus_tag="VVO74_000850"
     CDS             complement(14423..14911)
                     /gene="coaD"
                     /locus_tag="VVO74_000850"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU5694893.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPIENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(14901..15440)
                     /gene="rsmD"
                     /locus_tag="VVO74_000851"
     CDS             complement(14901..15440)
                     /gene="rsmD"
                     /locus_tag="VVO74_000851"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU5694894.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQITKEIGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYTKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(15505..16497)
                     /locus_tag="VVO74_000852"
     CDS             complement(15505..16497)
                     /locus_tag="VVO74_000852"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU5694895.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(16608..17291)
                     /locus_tag="VVO74_000853"
     CDS             complement(16608..17291)
                     /locus_tag="VVO74_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU5694896.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(17347..18087)
                     /locus_tag="VVO74_000854"
     CDS             complement(17347..18087)
                     /locus_tag="VVO74_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU5694897.1"
                     /translation="MTIITSKANSVVKNTKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFTLENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQREEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            18121..18399
                     /locus_tag="VVO74_000855"
     CDS             18121..18399
                     /locus_tag="VVO74_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU5694898.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            18477..19403
                     /gene="yidC"
                     /locus_tag="VVO74_000856"
     CDS             18477..19403
                     /gene="yidC"
                     /locus_tag="VVO74_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU5694899.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(19478..20272)
                     /gene="pflA"
                     /locus_tag="VVO74_000857"
     CDS             complement(19478..20272)
                     /gene="pflA"
                     /locus_tag="VVO74_000857"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU5694900.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(20398..21648)
                     /locus_tag="VVO74_000858"
     CDS             complement(20398..21648)
                     /locus_tag="VVO74_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU5694901.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(21715..22542)
                     /gene="purR"
                     /locus_tag="VVO74_000859"
     CDS             complement(21715..22542)
                     /gene="purR"
                     /locus_tag="VVO74_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU5694902.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(22809..23750)
                     /locus_tag="VVO74_000860"
     CDS             complement(22809..23750)
                     /locus_tag="VVO74_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU5694903.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(23740..24996)
                     /locus_tag="VVO74_000861"
     CDS             complement(23740..24996)
                     /locus_tag="VVO74_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU5694904.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(24998..25660)
                     /locus_tag="VVO74_000862"
     CDS             complement(24998..25660)
                     /locus_tag="VVO74_000862"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU5694905.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLLLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(25623..26279)
                     /locus_tag="VVO74_000863"
     CDS             complement(25623..26279)
                     /locus_tag="VVO74_000863"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU5694906.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(26290..27168)
                     /gene="rsgA"
                     /locus_tag="VVO74_000864"
     CDS             complement(26290..27168)
                     /gene="rsgA"
                     /locus_tag="VVO74_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU5694907.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(27170..28042)
                     /gene="rsmA"
                     /locus_tag="VVO74_000865"
     CDS             complement(27170..28042)
                     /gene="rsmA"
                     /locus_tag="VVO74_000865"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU5694908.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(28428..28574)
                     /locus_tag="VVO74_000866"
     CDS             complement(28428..28574)
                     /locus_tag="VVO74_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694909.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDKNMTNHLLLVQILVHGYLLDFA
                     SIEG"
     gene            complement(28567..29208)
                     /locus_tag="VVO74_000867"
     CDS             complement(28567..29208)
                     /locus_tag="VVO74_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694910.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(29210..31240)
                     /locus_tag="VVO74_000868"
     CDS             complement(29210..31240)
                     /locus_tag="VVO74_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU5694911.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(31317..31613)
                     /locus_tag="VVO74_000869"
     CDS             complement(31317..31613)
                     /locus_tag="VVO74_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU5694912.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(31933..32832)
                     /locus_tag="VVO74_000870"
     CDS             complement(31933..32832)
                     /locus_tag="VVO74_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5694913.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(32904..33464)
                     /gene="rnmV"
                     /locus_tag="VVO74_000871"
     CDS             complement(32904..33464)
                     /gene="rnmV"
                     /locus_tag="VVO74_000871"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU5694914.1"
                     /translation="MKERISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(33464..34237)
                     /locus_tag="VVO74_000872"
     CDS             complement(33464..34237)
                     /locus_tag="VVO74_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU5694915.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPMIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIRLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(34542..35435)
                     /locus_tag="VVO74_000873"
     CDS             complement(34542..35435)
                     /locus_tag="VVO74_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU5694916.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEVTPEY
                     KLETTPGGDKGGNIGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRLVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(35719..35853)
                     /gene="rpmH"
                     /locus_tag="VVO74_000874"
     CDS             complement(35719..35853)
                     /gene="rpmH"
                     /locus_tag="VVO74_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU5694917.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(35998..37212)
                     /locus_tag="VVO74_000875"
     CDS             complement(35998..37212)
                     /locus_tag="VVO74_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU5694918.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQMKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(37368..37661)
                     /locus_tag="VVO74_000876"
     CDS             complement(37368..37661)
                     /locus_tag="VVO74_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694919.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVKVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            37810..38262
                     /locus_tag="VVO74_000877"
     CDS             37810..38262
                     /locus_tag="VVO74_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU5694920.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(38297..39685)
                     /locus_tag="VVO74_000878"
     CDS             complement(38297..39685)
                     /locus_tag="VVO74_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU5694921.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELHRQL
                     KAYERHKERNKS"
     gene            39751..40713
                     /locus_tag="VVO74_000879"
     CDS             39751..40713
                     /locus_tag="VVO74_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU5694922.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLTMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(40710..40901)
                     /locus_tag="VVO74_000880"
     CDS             complement(40710..40901)
                     /locus_tag="VVO74_000880"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694923.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHVFEVVDRTDEVS
                     NHTYGKATLTWFAEIFEEY"
     gene            complement(40965..41975)
                     /gene="ccpA"
                     /locus_tag="VVO74_000881"
     CDS             complement(40965..41975)
                     /gene="ccpA"
                     /locus_tag="VVO74_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU5694924.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(42400..42999)
                     /locus_tag="VVO74_000882"
     CDS             complement(42400..42999)
                     /locus_tag="VVO74_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5694925.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVAVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(43001..44098)
                     /locus_tag="VVO74_000883"
     CDS             complement(43001..44098)
                     /locus_tag="VVO74_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU5694926.1"
                     /translation="MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMCEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     DSMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(44098..44835)
                     /locus_tag="VVO74_000884"
     CDS             complement(44098..44835)
                     /locus_tag="VVO74_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5694927.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGDINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(44837..45721)
                     /locus_tag="VVO74_000885"
     CDS             complement(44837..45721)
                     /locus_tag="VVO74_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5694928.1"
                     /translation="MDMIKVQGLHKNIKGKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLSVTSSQLDYIRGYLPQENVIVQKLKVKELVAFFQSIY
                     PNPLSNQEIDQLLQFDKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVQDLKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(45708..45902)
                     /locus_tag="VVO74_000886"
     CDS             complement(45708..45902)
                     /locus_tag="VVO74_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694929.1"
                     /translation="MKKAFLYLFIGLSLVVWLVEMFTGWFDQALLRQFIRGAWGLGFM
                     IFIAFPMGMEWLKGEYHGHD"
     gene            complement(45899..46090)
                     /locus_tag="VVO74_000887"
     CDS             complement(45899..46090)
                     /locus_tag="VVO74_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694930.1"
                     /translation="MKNKMIVAMSLVAAGVMTYLMFSGLDEDFYHFPWELFAGFGMMS
                     WLIREGLKLVSDVKKEFEK"
BASE COUNT        13334 a        10802 c         8834 g        13619 t
ORIGIN      
        1 tattccatgt tattttgagg aagatattgt gaaagtcaaa gatgatgata aagttgagtg
       61 gaatttgtta gaatttcaaa aatttagagc atttttgact tagtaatctg tgttgaaggc
      121 tcaaaaccta tggtaaaaaa gtaactttga aaacgtattg cctccaaaga tttagttaaa
      181 taatgattta acacaaaaag aaattattga agttctggaa agatgttgtt tcagtattga
      241 gaaaaggtgg gaaaaacttg cgattttcac agagaaagga agaaaaagta tagaaatata
      301 gtcaattgaa acaagaacag gataaaagaa ccttttgtgc catatttttc tcctttcgct
      361 ttacaattgg attgaacacc tttattgtat cgcgtttgga gtttttttgg tataaccttc
      421 gacgcgcacc cgcatagcgg gtgttttttt gtctcgcacc taacggagcg agacgaacta
      481 atagtcactt aatcaaaaaa cgcaccatat caaaaactaa aaagtttgat atcatgcgtc
      541 atgtcttaaa ctaattgact atactttcta ttcaaatgag cttttaacca attgattgag
      601 ccaatccact cttaaaacca aagagcaatt tctcgcttag ctgactcttc tgaatctgaa
      661 ccatgtacaa cattttggat aacctcattt tctccagcag cttttgcaaa gtcacctcga
      721 atagtgcctg gtaaagcttc ttctggacga gttgcaccca tcatggtccg ccaagtttcg
      781 attactttgg gaccagaaat gacacccaca agaactggac ctgaagtcat gaattcacga
      841 atcggtgggt aaaaactctg accaaccaag tcctgatagt gctggtcaat caactcttct
      901 gaaacctgtg aacgaaactc caatttttcg attgtaaatc cacgttgttc gatgcgcttt
      961 aacacttcac ccactagccc tctttttaca ccatctggtt tgatgataaa gaatgtttgt
     1021 tccatacccg tctcctttgt cagcttcttt cttttatttt accacatttc gtggaaaaat
     1081 ggagaaagtt ttcagaagag agaatgagag aacccgaggg ttctctcatt ctctcttatt
     1141 ctactgtttc ttccacagtt tcaacggcag tatccacaac tacttctgtt gtttcttcat
     1201 ttccttcttc ctctactgga ggattaaggt attcttcttc gttgacagca tgtggttcaa
     1261 ggttacggta acgggccata ccagtaccag ctgggatgat cttaccgatg ataacatttt
     1321 ctttaagtcc aaggagatgg tctttcttac cacggatagc tgcgtcagta aggacacgag
     1381 ttgtttcctg gaaggaagcc gctgacaaga aactgtttgt ttcaagtgag gctttggtaa
     1441 ttcccataag gactgggcga cctgtcgctg gaactccacc tgcgataagg acatctttgt
     1501 tggcatctgt aaagtcattg atatccatga gggtacccat gagaagatct gtatcacctg
     1561 gatccatgac acggacttta cggatcattt gacgaaccat tacctcgatg tgtttgtcac
     1621 cgatttctac cccttggcta cggtaaactt tttgtacttc accgagaagg tacgtttcaa
     1681 ctgacaagac atcacgaact gcaaggagac gttttggttg gatagaacct tctgtcagag
     1741 cagcaccacg cgctacttgg cccccaactt cgacacgcat acgagctgta aatggaacga
     1801 catattcacc ttcgccagtt tcacccttaa caaagacttt cttggtacga gttgatgcat
     1861 cctcttcgat agcagtaact tgtcctttaa cctctgtgat aaccgcttcc cctttaggat
     1921 tgcgggcttc aaagatttct tggacacgag gaagaccctg agtgatatcg gtatttgagg
     1981 caaccccacc tgtgtggaag gtacgcattg taagctgtgt accaggttcc ccgatagatt
     2041 gggcagcgat tgtaccaact gcttcaccaa cttcaaccgc atcaccagtc gccaagttga
     2101 taccgtaaca gtgacggcag acaccgtgac gagtgttaca tgtaaataca gaacggatag
     2161 tcacttcttc cacaccagca ttgacaattt cacgcgcctt gtcttctgta atcaattcat
     2221 ttggaccaat aatcactgca ccagtttctg gatgtttaac agttttctta gtgtaacgac
     2281 cgttgagacg ctcttcgaga gactcgatca tctcttttcc ttctgcgata gaacggatca
     2341 agagaccacg gtcagttcca cagtcgtcct cacggatgat aacgtcttgg gcaacgtcga
     2401 ccaaacgacg agtcaagtaa cctgagtcgg ctgtcttaag ggccgtatcg gtcatacctt
     2461 tacgagcacc gtgagttgag aagaacattt ccaataccga caaaccttcg cggaagtttg
     2521 aaaggattgg caattccatg atacgtccat tcggagcagc catcagacca cgcataccgg
     2581 caagctgtga gaagtttgag atgttaccac gggctccaga gtccatcatc ataacgattg
     2641 ggttcttagg atcttgatta gcaatcaagc gtttctcaag tttttcacgg gcagcacgcc
     2701 attcagctgt aacagcattg taacgctcgt cgtctgtgat cataccacga cggaattgtt
     2761 tggtgatttg ttcgacacgt ttgtgtgatt cttcaatgat ttcagccttg tcatcaacga
     2821 ctgggatatc ggcaataccc actgtcaatc ctgcaagagt tgagtggtgg taaccgaggt
     2881 tcttcatgcg gtcaagtagg gcagaagttt ctgtcgtacg gaaacgtttg aagatttcag
     2941 cgatgatatt tccgaggttt ttcttcttga atggagggtt gagctcaaga ttgctgatag
     3001 cttccttgat atctccacca agtggcaaga agtatttagc tggaacacct tctgtcaagt
     3061 tggcattgtt tggttcttgc aagtatggta gcccctctgg catgatatcg ttgaagagaa
     3121 ttttaccaac tgttgtaagc aagaccttat gtctttgctc ttctgtccaa ggcttgttga
     3181 ggctgtctgt tgcgatacca acacgtgagt ggaggtgaac ataaccattg cggtaagcca
     3241 taaccgcttc gtcacggtct ttgaagacca ttccttcacc ttcgcgacca gcttcttcca
     3301 tggtcaagta gtagttaccc aaaaccatgt cctgagatgg agtaactacc ggtttcccat
     3361 ctttcgggtt caagatgtgc tcagcagcta gcatgaggat acgagcttct gcttgtgctt
     3421 cttctgaaag tggtacgtgg atggccattt ggtccccgtc aaagtcagca ttgtaggctt
     3481 cacagacaag tgggtgcaag cgaagagcct taccatcaat caagactggc tcgaaggctt
     3541 ggatacccaa acggtgaagg gtcggtgcgc ggttcaaaag cactgggtgt tctttaatca
     3601 cttcttcaag gatatcccag atacgctcat ctccgcgttc caccaagcgt ttagctgctt
     3661 tgacgttttg cacgatatca cgggcaacga tttcacgcat gacaaatggt ttaaagagtt
     3721 caatcgccat ttcacgtgga acaccacatt ggtacatctt aagagttgga ccaacggcga
     3781 taacggaacg tcctgagaag tcaacacgtt taccgagcaa gttttgacgg aagcgtccct
     3841 gtttaccttt aagcatgtgg ctcaatgatt tcaatggacg gctacctggt cctgtgattg
     3901 gacgaccacg acgaccattg tcaatcaaag cgtcaactgc ttcttgaagc atacgcttct
     3961 cattttgaac gatgatacct ggtgcattta actcaagcaa acgagccaaa cggttgttac
     4021 ggttgataac acggcggtaa aggtcattca agtcagatga ggcaaaacgg ccaccatcca
     4081 actgcaacat tggacgaaga tctggtggga taaccggaag gatgttaaga atcatccatt
     4141 caggtttgtt tccagacttg taaaaggcat ccaaaacatc caaacgacgg atggctttga
     4201 cacgtttttg tccagtagct gttttcaatt cttctttgag ttcagcaatt tctttttcaa
     4261 gatctacttg cttcaaaagg tcttggatgg cttccgcacc catcttggca acaaatgaac
     4321 cataaccata ttcacgcaag cgctctcggt attcgcgctc tgtcatgata gacttgtgct
     4381 caagtggtgt atccttagga tcaatcacca cataagccgc aaagtagata acttcctcga
     4441 gggcacgagg gctcatatca agggtcaagc ccatacggct tggaatcccc ttgaagtacc
     4501 agatgtgaga tacaggagct ttcaattcga tatgtcccat acgctcacga cgaactttcg
     4561 tacgcgttac ttcaacccca cagcggtcac aaacaattcc tctgtaacga atgcgtttgt
     4621 acttaccaca agcacattcc cagtcttttg taggaccaaa gatcacttca tcaaagagtc
     4681 cttcacgttc tggtttcaag gtccgataat tgattgtttc aggttttttg acttctccat
     4741 aagaccatga acggacttta cttggagaag ctagggtgat ttgcatactt ttaaaacgat
     4801 ttacatcaac cactatttct tccctttcta ttctaagtga actgcttatt cttgttcagc
     4861 agcttcttct gttgcttccg cttttgttgc tttctcagct tcttcagctt caaaggctgc
     4921 tttagcctct tgggctgctt tttcgcgggc tttttcaagg tcatctacgt ggatgacatc
     4981 ttcgtccatt ccttcatcca agtcgcgaag ttccacttct tggtcatctt cgtctaggac
     5041 acgcatgtca agaccaagag attgcaattc tttgacaaga actcggaagg attctggaac
     5101 acctggtttt ggaattggtt tgccttttgt aatagcttca taggctttca aacgtccgtt
     5161 gatatcgtcc gacttgtaag tcaagatttc ttgaaggaca tttgacgcac cgtaggcttc
     5221 aagagcccaa acctccatct caccgaaacg ttgtccacca aactgagctt tacctccgag
     5281 tggttgttgg gtaacagttg agtaaggtcc gactgaacgc gcatgcaatt tatcgtcaac
     5341 catgtggtgg agtttaatca tgtacatgac tccaacagaa acacggttat caaatggttc
     5401 acctgtacgt ccatcgtaaa ggattgtctt ggcatcgcta tccatacctg cttctttaac
     5461 agttgaccaa agatcttcag agcttgctcc atcaaagact ggtgtcgcaa tgtgaatacc
     5521 aagagtacga gctgccatac caaggtgaag ctccataacc tgaccgatat tcatacgtga
     5581 tggcacccca agtgggttca acatgatgtc gactggagtt ccgtctggaa ggtaaggcat
     5641 gtcttctaca ggaacgatac gagagacaac ccctttgttt ccgtgacgtc cggccatttt
     5701 atctccgacc ttaatcttac gtttttgagc gatgtaaaca cgaaccaaca tgttaacacc
     5761 tgattgcaac tcatctccat ttacacgtgt aaagatctta acatcacgaa cgacaccatc
     5821 ggcaccgtgt ggtacacgaa gagaagtatc acgcacttca cgagacttgt ctccaaagat
     5881 agcgtgcaag agacgttctt cagctgaaag atctttctca cccttaggtg ttactttacc
     5941 tacaagaata tcaccttctt taacctcagc accaatacgg ataatcccca tttcgtcaag
     6001 gtctttgagg gcatcttcac caacgtttgg aatttcgcga gtgatttctt caggcccaag
     6061 ctttgtatcg cgcgtttctg attcgtattc ttcaaggtga acagatgtgt agacatcgtc
     6121 cttcaccaag cgttcgctca tgataacggc atcctcgaag ttgtaacctt cccaagtcat
     6181 gtaggcaacg attgggtttt gtccaagcgc catttctcca ttttccatag aaggtccgtc
     6241 agcgatgaaa tcgccttttt caacgacatc accaactttt acgagagtgc gttggttgta
     6301 agcagtacct gagtttgaac gacggaattt ttggatgtgg taaacatcca atgaaccatc
     6361 ttcacgacga acttctacct tgtcagcatc tgcgtaagta actttaccat catactgagc
     6421 aatcacagcc gcaccagaat cgtgggctgc ttggtattcc ataccagtac caacgtaagg
     6481 tgcctgagga ttaatcaatg gcacagcctg acgttgcata ttggctccca tgagggcacg
     6541 gttggagtca tcgttttcca agaaaggaat acatgctgtc gcaacggcaa ctacctgttt
     6601 tggtgaaacg tccatgtagt caacaatatt agctggatac tcttggttga ccccttggtg
     6661 acgtcccatg acaatcttct cagcaaaggt tccatcttca ttcagacgag agttagcctg
     6721 agctacagta tattcatctt cttcatcagc tgtcaaccaa acaatttcgt tcgtgacaac
     6781 acctgtttca cggtcaacct tacggtatgg tgtttgaaca aaaccatatt tgttcaagtg
     6841 tccgtaagat gacaagttat tgatcaaacc gatgttaggt ccttcaggtg tctcgattgg
     6901 acacatacga ccatagtgag tgtagtgcac gtcacgtact tcatatccgg cacggtcacg
     6961 agtcaaacca ccaggtccta aggctgacaa acggcgtttg tgagacaact cagaaagcgg
     7021 gttgtgttgg tccatgaact gtgacaactg tgatgaacca aagaattctt taactgcagc
     7081 tgttacagga cggatattga taatttgttg tggtgtcaag acttcattgt cctgaacaga
     7141 catacgttca cggacattac gttccatacg agaaagtccc aaacgtactt ggttggcaag
     7201 caattcacca accgcacgga tacgacgatt tccaaggtgg tcgatatcat ctacacggcc
     7261 aagtccttca gccaagttga ggaagtagct catctcagca aggatatctg caggagtcac
     7321 cgtacgaacc ttgtcatctg ggttagcatt accaatgatc gttacgacgc gatctggatc
     7381 agttggagca ataaccttga atttttgaag aacaacaggc tcagtcacaa cggctgcatc
     7441 gtttgggatg tagacaatct tgttcaagtc gccatccaaa tggctttcaa tgctttcaat
     7501 cacgctacga gtcataatcg taccagcttc taccaagatt tctccagttt cagggtctac
     7561 caatggctct gcaatggttt ggttgagcaa acgtgtttta acattgagtt ttttattgat
     7621 tttgtaacga ccaactgctg ccaagtcata acgacgtggg tcaaagaagc gagctacaag
     7681 caagctacgt gagctttcag ccgtcttagg ctcacctgga cgaaggcgtt cgtaaatttc
     7741 tttcaaggct tcgtctgtac gagagtccat tggattcttg tggatatctt tttcaacagt
     7801 gttgcgaacc aattcgctgt ctccaaagat atcaaagatt tcatcatcac ctgagaaacc
     7861 aagagcacga accaaggttg taaatggaat cttacgagta cggtcaatac gagtgtaggt
     7921 gatatctttt gagtcgcttt caagttccaa ccaagctcca cggttaggga taacagttga
     7981 accatagccc accttaccat ttttgtctac tttgtcgtta aagtaaacac ctggtgagcg
     8041 gaccaactga gaaacgataa tacgttcacc accattgatg atgaaagtac ccatttctgt
     8101 catgattggg aaatcaccaa agaaaacttc ttgggtcttg atttcgcctg tttctttatt
     8161 gatcaaacgg aaggttacaa aaattggtgc tgagtagcta gcatcgtgga tacgagcttc
     8221 ttctagcgtg tattttggtt ccttgatttc atatccaaca aattccaact ccattgtgtc
     8281 tgtgaagttt gaaattggca atacatcttc aaacacttcc ttaagaccgt ggtctaggaa
     8341 agctttgaat gagtcagttt gaatttcaat caaatttggt aagtcaagaa cttctttgat
     8401 tcttgaaaaa ctacgacggg tacgatgttt cccgtattga acgtcatgtc ctgccaagat
     8461 gattctcctt tgtaaataag ttccaagcct tgtcaatcag gcttttctaa tcgtcatatg
     8521 gttgtaaacc ccttatcacc gtgtcctctt gacgaatttt cagaatcttt aagcctctgt
     8581 tacaaatgct cataatcttg aaaaaaagca caaaaagagc agctaaatct gactttttca
     8641 gaagatttaa ctgctgtgag ccttgtctgg acaatatttc agacaaaacc tacgacaaat
     8701 gattacccat attataccct atttagctag atttttcaag gggtttcagt aggtttttgg
     8761 taaatttttt cccatagaaa acttggcatc acattcgaat cacgctatgg tacaaaaaac
     8821 tgaaaaaact attgactgaa aatcattttc aaggtataat aataaacgtt aaggcggtat
     8881 agccaagtgg taaggcacgg ctctgcaaaa gcttgatcgt cggttcaaat ccgtctaccg
     8941 ccttctataa cttgatttat caggtttcaa atgaacagaa agcccaattt gaagggcttt
     9001 ttttattttc cctcgaataa atacgtataa ctttaaaaac ttttggagcg agtttgtggc
     9061 agagttcttt ccatggcata attccctttt gaaatcaatt gaaaaaagct tcgtcacgcc
     9121 tggtgacaaa agcctctagt ttattctgtt tcttcttcta tttcgacttc tgtgatttgg
     9181 acttttacct tggtaacacg tccattcttc actttatcat tggttaagat aaactgtttg
     9241 ttttggctga ccaattcata gctgagtttc tcagtcgttg gaatggttcc cactcctgtc
     9301 aaataataac cagcgatggt atcaacgtca tcactttcca gctcaacatc aaagtaatta
     9361 ttgaaatcat tgagggtcat agttccttga acaatgtagg tatcctcgcc aatctgatga
     9421 acatctattg ctgctttgtc cgtttcatca tcaatttcac caacaatttc ctctaagagg
     9481 tcttccaaag tcactaaacc agccatacca ccgtattcat ccagcaagat tgccatttgt
     9541 ctttgggtat ttcgcagttc ttttagcaag tcatccacaa aaatagtttc aggtacaaaa
     9601 agtggatctt gtaaaattct cttccaaaca atattgtcaa aaccgtccac aaagcctgcc
     9661 ttaaggagac tcttggtgtg aatgattcca attacattgt ccttatcccc atcataaacc
     9721 gggatacgag aataattttg ttttaaaata ctttggataa tggcttgact atcatcctga
     9781 atatccacca taaaggcatc cgttcgagga accataacct ctcgtgccat cagttcatcg
     9841 agcgaaaaga caccttgtag catctcaatc tcatcagcat ccaatgtttc ttcactattt
     9901 gtcagcatat aggcaatttc atcacgggtc attttttcat ccgcatcatc gaatgacata
     9961 ggagtcaaat ggctcaagaa attggtcgaa gcagctaaaa gccaaacaaa aggactgact
    10021 agttttccga tcccaatgat aaccggcgct gtacgaattg ccaaggcatc ctttagatta
    10081 agagcgattc tcttaggata taattcccca aaaacgatgg aaatataggt caaaaatgcc
    10141 aaggatagaa aagttgccac ggcttgtgct gtttcgccat tcccaagcca agaggcaatc
    10201 acacgtccta gagtatcagt taaactcgcc cctgataaga ttgtaatcag ggtgattcct
    10261 acctgaatgg ttgataaaaa gtggttagga ttttctagta ccttcagcag gcggatgtag
    10321 cgtctgtctc cttcttccgc cttttgttca actcgggcac gattaagaga aaccatggcc
    10381 atttctgtgg ctgagaaaaa ggcatttaat accgtcaaga taaacaataa aacaaattgt
    10441 agcaacaaat tctgactact tgggtcttcc atagttcttc tcctaaaata gtatcttatc
    10501 ctttattata tcacaaaatt taatccaata catattattt ttttcttagc gtaacttcca
    10561 tctctctccc aaaactggaa gttagtctaa gacggatttc cactgatttc acgcgttttt
    10621 ctcatactaa aagctaggtt gtgggaaact ggaagttagt tttagaagtt actatttttt
    10681 cttagtacct attctagccc tgcttaaact agtaaaaaga actcctacat ccataagtga
    10741 cataggagtt taggcttatc ttttactgag ttacagttac ttctccagtt cggtaatcca
    10801 gttgaagtcc cttttgaaca ttgggaacta gaacattgaa ttccaattct ccatccgaag
    10861 acttggcttc aatctgtgaa gctgagggaa ctaaatcctc gtttgaagcg tagtaaaggg
    10921 ttacacggta acggacacgc ttgttttggt ccaaggcttt acgcaccttg ctttcatagt
    10981 agttttgacc agtcgaatac tcggcttgtg cctgatttgc ccaggctgtc tgaacagcaa
    11041 tgtttttagg attgcttgtt gaggcatcaa aaccatccaa accaccgatt aaggcatagc
    11101 ctaacaaatg acctctatcg actgcatggg tataagagcc ctttagattc ttgacctgat
    11161 gccaacctgg aggagtccaa gaagttgaac cattcccagt ttctttacga ttcttgtact
    11221 gacgagtggc cttagacaag agggcattag ctacggttgg aacagtttcc ttgcccactg
    11281 tctttgtttt attgtcagcg tagggcttac ttgaaacctt ggcatctaga tttgttttat
    11341 taccattgac gataaaagca cctgagccat tccactccag actccccttt atttgactct
    11401 tgactgcgtc tgttaagaca ctctctgcca atgcttgact aggagcttca gacgcttgtt
    11461 ttttctgact aagattggtt ttgggactat taggtgccga ctgcatctgc ttgatataat
    11521 agctccctgt agacaaaagc aataacacta gcagtccgat tagtgtctgt cttgtttttt
    11581 tgttcatatt tctccttatc tttagaaaaa ggctggttct ccagcctaat ttcctgtaaa
    11641 tttatgaatc aattcctgcc attttgctgg agacaggata gcccatggat cttgaccctt
    11701 gcccaagatt ccataaccta ccattagacc gattcctaga gccagagtac ctaaaatcag
    11761 tactatgatg actaaaagta aacgattgat tacgtagctt gatttcttat tcatcttcat
    11821 cgcttgcctc aatccgctga atcttagcac ctagctgcgc caacttctca tggaaaccgt
    11881 agtaacctct atccaagtga accaatttac cgaccacagt ttctccctgt gctaccaaac
    11941 ctgtcaaaat caaggctgca ctggcacgaa ggtcagttga aagaacttct gctccctgca
    12001 aaggctgtcc accaacaata cgagctgtat cacggataat ctcagaatgc aagcccatgc
    12061 ggcgcatctc ttctaggtgt tggaaacgat tttcgaaaac tgtctccacc atggttgatt
    12121 cgccttttgc aactgtcatc aaggctgtaa attgagcctg catatctgtt ggaaatcctg
    12181 ggtggggcaa ggttttcaca tgaacagctt ttagattttc tagttgagaa cgaacacgaa
    12241 ttccttcgtc ttcttcaatt acttcaacac ccatttcaag taacttggca atcaagggac
    12301 ggttgtgctc ccagacagcg tctcgaatca agacatcacc accagtcatg gcagcagcta
    12361 ccataaaggt tcctgcttcg atacggtctt ggactacatt gtgagtcgta ccatgaagtt
    12421 tctcaacacc agtaatggtt atagtctctg taccagcacc tttgaccttg gctcccattt
    12481 cattaaggag aatggctaag tcaacaatct caggctcacg cgcagcattc tcaatcactg
    12541 tcaccccatc agccagagtc gctgccatca tcaagttctg cgttgcacca acacttggaa
    12601 agtccatata gatatgagca ccatgcaagc gttctgcctt ggcttcgatg taaccagctg
    12661 tctgactaat cttaaccccc atagcttcca gacctttcaa atgaagatca ataggacggc
    12721 taccaatcgt acaaccacct ggcatggata ccttggcatg acccacacgg gcaaggattg
    12781 gccctaatac aacgatggag gcgcgcatct tgctgacata cttgtaaggg gcttcctcag
    12841 tgatgtcgcc agtagcatcc accttgacaa gatgagcttc ctcatcaaag tcaaccttgg
    12901 cattcaaacc accaactacc tgattcataa taaagacatc cgacaaaatc ggaacattct
    12961 gcaagacggt ctttccttca cttgctagaa tagtcgctgc caacaagggt aagactgcat
    13021 tttttgctcc ctcgatcgtc acgcttccta ccagacgatt atcgccacct tgaaccacaa
    13081 ttttatccat actcgtttcc tttactcttg atttcataat aatcctctaa gcgcttcttg
    13141 ccacaaatga tacaggctaa taaagaaaga actcaggatg tagcctatga caatgctaaa
    13201 aaaggctact aataaacgaa cttttcttgt attctcatct gtcactttta aaaccttctc
    13261 ccatctaaca agatccttta aaaggtaaaa actcacataa ataaagagca tatgactact
    13321 tagagtgaat aataattgaa ccatttgact attataccat cttctctgtt tgtgcgctag
    13381 tttggaaact tcactcaaaa attagggatt gtttttcaag taatcaatcg catcttgtag
    13441 ggttttaacg ggcacgattt tcatatccgt cttgattgtt ttagccgctt ctagggctgt
    13501 ttggtagttg tttttcgcgt ccggatgcgc cttttgttct tcttcgctaa cagggttatc
    13561 aggagcaaag aaaatagcag cacctgccct agccgaagct acaaccttct tatcaatacc
    13621 tccaatgtct cccacattac catcgcggtc aatggtacct gtaccggcaa caatacgacc
    13681 attacgaaga tctgggtgag ctatttgagt atagatagct agactaaaca tgagaccagc
    13741 acttggaccg ccaataccag ctgttgaaaa gctaattggg acattgctga ttacctctgt
    13801 acggtcaatc aagccgattc caattccatt tttgccattt tccaaggtga taatctttcc
    13861 ttctgcagac ttggtttgcc catcctcttc ataggtgacc ttgacggaat cccctaattt
    13921 ttgagaactg acgtaatcaa tcaagtcttt ggaactatca aaggtctgat cattgactgc
    13981 tgtgactgta tcagagatat tgagaatccc tttaaaggtt gaattatccg tcacattcaa
    14041 aacataaact ccaaagtact tgagttcgat atccttacca gctgttttta gtccttgata
    14101 cttggccata ttttgcgatg tttgcatgta gaattgattg attcgcataa attcaacatc
    14161 ggaagaacca cctgtagtct cctgagcact acgaatatct gtaaaaggtg tcaaccaagc
    14221 ataaatcata tgagctaaag tggcatgttg aacaccaacc gtaacgaatt gataggcacc
    14281 agcttcctta tcttctgtgt catttatttt aaggacttgg cgaatatctt ccgaaccacc
    14341 tggaacctct atataataag gcaagggcac tacaaatgcc aagaaagtca caatcaaggc
    14401 cgcaatgacg tataagggcc atctaatctt ttttttcatt tcttatttcc tccaaaatac
    14461 tctcgggaac atagcaggca atatcctgac caaacttcaa aagctctcta acgcctgatg
    14521 aactgatata gagatgttca ggtcgactat gtaaataaat agtctctata tcagaagaca
    14581 gctgatgatt gtagtaatca aaactggctt catattgcaa atccgacgca ttcctcaaac
    14641 cacgcactag acaagtagca cccaatcttt ttgcaacatc gaccaccaat tcatcatgag
    14701 aagccacgac ttcaacattt tccagatgtc ccaaagcctt ttctagcccc cgtttacgat
    14761 tttcgatagg aagaaatcct tgtttgtggg gattaaaaaa aataccgaca tagagcttat
    14821 caaagagtct gctcgcccgt tcaatgatat ccagatgccc atttgtcatc ggatcaaatg
    14881 agcctgtgaa taagccaatc ttatctgaca tagactgtca ccttactaat tccataaatc
    14941 ttttccttcc agatacccag acaggcaatt tcttctggaa gttcaacggc cttatccgtc
    15001 tcgcacacaa ccataacatc ttcagaaaaa agctctctct cagccatttt ttcaatatct
    15061 gctacgattt gttccttggt atagggaggg tctaagaaaa cgaggtcaaa ttccccagat
    15121 acctgttcca atgccctttc tgcatccatc ttgaggagtt gaaattttcc aatttccttg
    15181 gttatctgga tattttcagc cacgatggtc tgagccttac ggtctcgctc caccaaaaca
    15241 gcactggaca tgccacgcga tactgcttcg atagataaac caccactacc tgcataaagg
    15301 tccaagactc gtcccccttc aaagtaggga ccaatcatgt taaaaatggc tcccctaacc
    15361 ttatccgaag taggtcttgt cgtcttgcct tctagtgtct tgaggggacg tcccccatag
    15421 attcctgata cgattttcat actgtttatt ataccaaatt atagacaaaa agagaaagaa
    15481 aaccgaacct tgcggttcga ttctctacaa aatattttcg taagtatcgc ggacttcttg
    15541 aggccaaaca cttgtttgca cttctccgat gtgtctcttg cgaagtagga acatggccat
    15601 acgagattgt ccaattcctc caccgattgt caatgggaat agaccattca acaaagactt
    15661 gtgccattcc aattccaagc ggtcttcatc acctgtaatt tccacctgac gtctaagagt
    15721 ttcttcatct acacgaattc ccatagaaga caactcaaag gctccaccta aagactcatt
    15781 ccagacaaga atatcaccat ttagaccctt gtagccattc tcagactcgc ttgtccagtc
    15841 atcatagtct ggtgcacgtc catcgtgcgg tttaccatct ggcaactcgc caccgatacc
    15901 aatcaaaaag acggctccaa attctttaca aatcgcattt tcacgttctt tcggtgtcaa
    15961 gtctgggtag cgttctacca attcttctgt atggataaag gtgatttgtt ttggcaagat
    16021 agactcgatg tcatagcggg cttcaacagc tagctcagtc aggcgaatag ccttataaat
    16081 cttctcaact gtttctttta gataaacgat gttacgctta ccatttggga taaccttctc
    16141 ccagtcccac tggtcaacat aaacagagtg ggttgcatcc aaggaatcct catctggacg
    16201 aagggctttc atgtggacaa agagaccctc tccttcacca aagccaaaac gagccaaggt
    16261 gtggcgtttc catttagcaa gtgagtgcac cacttcataa gtagcatcag ggatttggag
    16321 aaccttgacc gatactggat tttccacacc agacaggttg tcctgcattc cgtcaccgac
    16381 cttactcaag ataggacctt gaacttcgac aacttctagc ttatctttca aatactgggt
    16441 aaaagtgttt ttgacaaagg aaatttcttc ttgttgatgg ataaaacttt tcttcataga
    16501 caactcctca aaaatttaat aaacgtatta tacacctatt tccaagaaaa gaaaagagaa
    16561 aatttaaaaa aatcagtgtc actcaaaaca ctgatttcat agacctttta gtcattgcga
    16621 ccaaagatac gtagaatact taggaaaaga ttgataaaat caagatagat gctgagagcc
    16681 attgacacca cccaacctgt cgctacacga ccttgtgatt gttcataggc gaggcgaatc
    16741 ttttggttat cccaagcaat caaccctgaa aaaaccaaaa ccatggctac gctaatcata
    16801 taatcaaaga agccactagc caagaaaata ttgactacca tagcaatcag taaaccaatg
    16861 agagctgcca tcattgctcg accaatccca ctcaagtctt tcttggtaaa gataccaact
    16921 gccgccatga caaagaagag aagggcgctc gatacaaagg cagataaaac tgtacccgga
    16981 gtatagaaag ccaccacaaa actaagggta aagccgttta aaacggagta aagtaaaaat
    17041 actggaagag cagctggact atttcttgaa gccatgctac tggcaacgaa aaccaaagcc
    17101 aactccgcaa aagtagcaat ggtcaaccag agacgcccct gcatcaaaaa gtaaaccaac
    17161 tgagactgaa agaccgtcaa cataaggcct gataccaaag cagatagtcc gattcccaga
    17221 ccaacaaagg cataaacctt agcgtaaaat tgattgagac ctgcacggtc atgtataata
    17281 gtgtgattca tccatttctc cttttctgtg aacatctttc cttgattata acaaaaaaag
    17341 ttaaaattag cttaaatgga agattaaaat accggctgca accgcaacat tcaaactctc
    17401 ggcctgcccc ttcatgctaa tatggaccaa ctggtctgca ctttcagcca taaggggact
    17461 aattccttga ccctcatttc ccataactag tacaaaattt tctatagaag gcagttctct
    17521 gtaatcaaca gaatctttag atagggttgt tgctagcact gggatagcta cctttttagt
    17581 ttcgtcaaga agcgcttgac tagtcatccg gtaaatgggc agatggaaat gactaccttg
    17641 catggaacgt agggttttga gactgtagat gtctgccgac ttatctgaaa caatcactcc
    17701 tgtaaaacct gctgcatccg cagttcgaat gatagttcct acattaccag gatcttgcac
    17761 atcttccaaa aacaagaact tgccctgact caaatcagct tgtcctactt cttctctttg
    17821 aaccacggca acaattccct gtggagtctg agaatccgcc aaatctagca aaatatcctc
    17881 tgacacccag acagtttgcg aaaaagtagc taactgatct cgataatttt ctagggtaaa
    17941 gattttctca atcgtcactc cagcttgaac agcttcttca aacaagtgcc agccttcaat
    18001 caaataggct gacttgcggt attttttttg gtgtaatttc ttggtatttt ttaccacaga
    18061 attggctttt gaggttataa tagtcataga aatattataa cacaatcaaa ggggtttggt
    18121 atgcaaaagg ttagaatgat tgcccaaggt agggtacagg gagtcggctt tcgttggggt
    18181 gtttacagct tggcccttga aatcggtggc atcacaggtc gggtatggaa taacgacgat
    18241 ggcacagtgg aaatcttagc ccaagcagac tcatctgcta tcatggcaaa atttatccaa
    18301 gaaatccgaa aaggaccgac acctttttca aaagtaagct acttagatgt caaactaagc
    18361 aactttcctc cctactctga ctttaaaatc gcaaattagg tctccagaac tattgtatat
    18421 tttgtaaaaa aacagtagaa tagaaaggta taatttttaa agaaggaata aaaacagtga
    18481 aatctattaa acgttttgca ttctcggcta tgggagtggc tatgttgctt gtcttgactg
    18541 gctgtgtcaa tgtcgataaa accacaggtc agccaacagg atttatttgg aatacgatcg
    18601 gagcgcctat ggctgaagcc atcaagtact tcgctactga taaaggtcta ggctttggtg
    18661 tcgctatcat tatcgtaacc attatcgtac gcttgattat cttaccactt ggtatctacc
    18721 aatcatggaa ggcaacgctt cactctgaaa agatgaacgc tctcaagcat gtccttgagc
    18781 cacaccaaac acgtctcaaa gaagcaacta ctcaagaaga aaaactcgaa gcccaacaag
    18841 ccctctttgc cgctcaaaaa gagcacggca tcagcatgtt tggtggtgta ggatgtttcc
    18901 ctatcctcct tcaaatgcct ttcttctctg ctatctactt tgctgcccaa catactgaag
    18961 gggttgctca agcaagctac ctaggcattc ctctaggttc tccaagtatg attttggttg
    19021 cctgtgctgg tgtcctttac tatcttcaat cgctcctttc acttcacggg gtagaagatg
    19081 aaatgcaaag agaacaaatc aagaaaatga tttacatgag cccactcatg atcgtcgtct
    19141 tctccctctt ctcaccagcc agtgttacac tttactgggt tgtcggtggt ttcatgatga
    19201 ttctccaaca gtttatcgtc aactatatcg ttcgtccaaa acttcgcaaa aaagtccgtg
    19261 aagaactagc caagaaccca ccaaaagcaa gtgctttctc taaaccaagt ggacgaaaag
    19321 acgttacccc tgaacaacca actgctatca caagcaagaa aaaacacaaa aatcgcaacg
    19381 ctggaaaaca acgttcgaga taagaagaaa aaggcttagc tgatttgcta agtctttttg
    19441 caaatcaaaa gcccgatgtt tccatcaggc ttcttttcta tccatgtaca cgtttcatat
    19501 aatcttgata actttcggta tccatgagtt ttttagcgtt cttgacgcga tctgctgttg
    19561 gtggtttgac tccttcgagg gaatatggaa ttccaagttc acgccacttg aactcaccca
    19621 tggtgtgata aggtagaatt tcaaacttat caacattttt gagggtcttg acgaacttac
    19681 caagttcaat caagtcatca tctctgtctg tcaatcctgg aactagcacg tggcgaatcc
    19741 agacaggttt tccaatatct gatagatact gggcacaagc caagatattt ttattagttt
    19801 gtctagtgac aatcttgtgc tgttcttcgt tgatttcctt gatatccaaa agaaccaagt
    19861 cagtgacagc catgagtttg tcaaacttct caaggtaacg tggtttatta cggaaaggaa
    19921 gagcacaggt atccaaggta cagtggattc cttgttcctt agccttggtg aagagagcaa
    19981 tcaggaaatc aatctgcaag agagcttctc ctccactgac tgtaatccca cccttatttc
    20041 cccagaaacc acggtagcgc aaggcctctg tcaagacatc atctaccgtc cgttcacgtg
    20101 acttattgga ctccatagcc caagtgtctg ggttgtggca atactggcaa cgcatgtgac
    20161 agccctgcaa aaagacaata aagcgaatac caggcccatc tactgaccca aagctttctg
    20221 tcgaatgcac cattcctgtc acttgtccat aatcaattgt ttcttcagac atatcgttac
    20281 cttccttgaa aacgttttat agttttatta tatcatgact tgaaggaaaa acaagatttt
    20341 tgcctatttt ttagaaagca atctgttttt caatttcatt ttcaatctat tatcagatta
    20401 ttcttcaaaa tcgaagccat ataaggttgc aaaatagtcc tcagggcgct ctgcacggcg
    20461 gatttgacgg gctttacctt cttcggtata gaggatttcc gcagaacgta atttggcatt
    20521 atactggtag cccattgaaa atccgtgggc acctgtatca tgaatgacca gcaaatcacc
    20581 gatttctgta tgaggcagtt cgcgattgac tgcaaattta tcattgtttt cacagagtga
    20641 accaaccaca tctaccgctt cagctggtcc atctggatgg gtcacgttgc taatatgatg
    20701 gtaagctccg tacatagctg gacgcatgag gttgactgct gaggcatcca cacctagata
    20761 ggtacggtag gtttccttct tatgagtcac tcttgtgact agagcaccgt gaggtgccag
    20821 cataaaacga cccaattcgg tgaaaatctt gacctgacca agacctgctg acgtaagaac
    20881 ttcttcatac accttacgaa ctccctcacc aatcaaggcg atatcgttcg gctcctggtc
    20941 tggacgataa ttaacaccaa taccgccaga aagattgata aagtctagcg aaatgcccaa
    21001 cttttccttg atttcaacag ccagttcaaa gagctgacga gccaactctg gataatagag
    21061 atgggtcacg gtattggacg ctaggaagga gtgaatccca aaagtcttgg ctcctttttc
    21121 cttcaagata gcaaaggctt caaagagctg gtccttggtc atgccaaact tagcctcccc
    21181 aggattgtcc ataatgtctg tccccagttc aaaaacgcct ccaggattat aacgacaaga
    21241 gatgatttct ggaatgcctg ctactctctc cagatgttca atatcttcaa aggcatccaa
    21301 gttaatggtc gcacccaatt cacgtgcata ggcgtattcc ttgtctggcg tgttgttgga
    21361 agagaacata atctcagaac ccagaaagtc cagtttatgg ctcatcaaaa gctctacata
    21421 actagagcag tccacaccac aaccttcttc ttggagaatt ttcaaaatag ctggagttgg
    21481 agtagcctta actgcaaaat attccttaaa gcccttgttc cacgaaaaag cttggttgac
    21541 ggctcttgcc ttctcacgaa tccccttctc atcatacaag tgaaagggag tcgggaactc
    21601 ggcaacaatc gcttctaact cttctctatt gataaatggt gttttcataa gcttccttct
    21661 attctgtttg caaagaaagg ctgggacaat cgttccaacc tttagttcta tctcttattt
    21721 atcttcgtca aagatattgc caacctcaac atcgatggct tggttcttga catcaatatt
    21781 agttaccttc aagagtgact tgtagtcaaa ctgcttttca cgttcttctt gggcattgtc
    21841 cgcaaagacc gctacacctg ccagttctga gtcgaactcg cgcaagagac taatcatacc
    21901 gttgaccgtt ccgccacctt tcaagaagtc atccacaatc aagacacggc tgcctgcctt
    21961 aagactacgt tttgaaagga acattttctc gatacggtca ccacttgaac ctgaaacata
    22021 gttgacgcta acagttgaac cttcggtaat tttcaggtca cggcgcacaa tgacaaaaga
    22081 gacattgagg acattggcaa ctgcatttgc aagtggcaca cccttagttg ctacggtcat
    22141 aaccgcgtca attttttggt ccataaagct tttggcaata atacgaccaa tatttttcaa
    22201 gatggctggt gtgctaagca aatcagacag atagatataa ccacctggca agatacggtc
    22261 actttctgac aacttggtac gcaagtcttc aaccatttcc ttagcatcct gactcgaaat
    22321 agacggtgtg aagatgacac ctccgccagc cccagtcact gtctggatat gaccgatttc
    22381 aatttcctca aaggcgcgtt tgataatgac gatatcttct gagatggatg atttagcaga
    22441 ctcatacttt tcagcaaaag tattgagact agttagttta taaggattat taatcaaata
    22501 gttggaaatg acaaccatcc gatcacttct tcttaatttc atttctattt cctattccat
    22561 ttttattcaa aaaatcaaaa agcaaactag aaagctggtc gctggtggtt caaaacactg
    22621 ttttgagatt gtcgatagaa ctgacaaacc ctgtaatata cctgcatata tacatacgac
    22681 aaagcgatac taccctagtt tgaagatatt ttcgaagagt attcattttt gtcttttact
    22741 tattatacca tattcacata aaaaaacgaa cattcttatc ctaaaaaatg ctcatttttc
    22801 ttaaattatc aatctaaatc tggtttatag aaggaacgat tatccatagc gaagatttta
    22861 ttggtcatct ctcctttatc caccaaagcc agagctgttg acatcatcat catgcttgca
    22921 tccagattgt caatcatatg gataatctct gcctccataa tacgtggacg gactggactt
    22981 ccatattcaa gcaagccgtg gtgactgagg atgacatgac gaagcaaaac gacttcttcc
    23041 ttggtatcat cgatgccgag ttccataact gtcttggtaa tttcgctatc aatgagagcg
    23101 atatgtccaa gaagattacc tcgcactgtg tactctgtct ggtctggccc cgtcaactcg
    23161 atgaccttag ccaagtcgtg caacataatc cccgcataga gcagactctt attgagctga
    23221 ggataaactt cgctaatagc gtctgccaaa cgtaccatgg tcgccgtatg ataagccaac
    23281 cccgtttcaa aggcatggtg gttggtcttg gcagctggat aggagtagaa ttccttatca
    23341 tacttggtgt agagatttcg gacaatccgt tgccagacag gattttcaat tttgaaaatc
    23401 atttgcgaca tgtagtcacg aatttccttg acatcaactg gtgacttgac cttgaaatcg
    23461 gctgggtcat tgggttcacc agcttgaggc aggcggagag taatttgatt gacttgaggg
    23521 gtattgttat aaacttctcg gcgtcctttc atgtggacaa ccttacctgc ggtaaaggcc
    23581 tcaatgttat gaggttgggc atcccagagc ttcccatcaa tctcgccact atcatcttgg
    23641 aaggtaaagg ctaggtagtt tttcccagct cgagtttgcc tcaggtcagc tgatttgatt
    23701 aggtaaaagc cttcaaatag ctcatctttt ttcatgtgac taatcttcat attcttcctc
    23761 attttcttga aaatggagta gatcaagcgc aggctcgcct tctgacaact caatgtgacg
    23821 gagcgtccgc tcgatagcta tggtacgacg gtttaataat tcatcaatat tgccagaggc
    23881 atgttggaga tgtttttgtg ccttgaccag aataccacca aacttgccaa actcggtctt
    23941 gacactggca agagtcttgc tgatatggtc ggcactcttt tggatattaa gggtcttgaa
    24001 accaactgat agggagttaa gaagggctga tagggtactt ggtcctgcaa caataatctg
    24061 ttcttcccgt ctcaaatcat caaagaagac cggattgcgg acgatttctg agtagagacc
    24121 ttctgtcgga acaaacaaaa ctccaaaatt ggtcgtccga ggtggtgcta tgtacttgtt
    24181 cctaatatcc ctagcaaaac gcttgacact tgctaggagt gacttacgac agcgttcgat
    24241 ttcatccttg tcacctactt cataggcttc ttctaagcgg taataatctg ccagtggaaa
    24301 cttagagtca attggtaggt agacgtattc ttggtcgcct tgtccgggta acttgatggc
    24361 atactccact cgttcactag agttttcaac cgttgcgtat tctcgttcgt actgggcagg
    24421 tgtcatgatg tcttcaataa tttgccccag ttgcaattct cccagaatcc ctcgcgtctt
    24481 ggttccagag agaaccttgt taagagctcc gacatcacgg gcaactgtct gcatttctcc
    24541 aagaccacga ttgacagact ccagttgttt agaaactgtc tcaaaggaag cctgtaagcg
    24601 tgtctgcaag gtcttttcta gtttttcctc gaccgtctgg cgcatttgtt ccaaacgttg
    24661 ctcatttgat tcctgcaagg cttggagacg ttggtctgtc ttgtctctag tttggaggag
    24721 attatctgtc atttcttgac ggacttgggt caggccttgg tgcaattcaa tccgcacttc
    24781 ttgcaaacgg tcgctgacag ccacttccaa atctttttgg tctaactggc tggcttgtct
    24841 ggcttggtca aagcggtaat ccaactggtc tgacaaatga tctgcctgat cctccaagct
    24901 cttacttaag tgtttctcct gcctatcctg tctttgccaa atcagaaaga gaccagctag
    24961 gttggcaatt aataatagaa taagtaaact ttccatccta cctcctgtcc ttgctatgca
    25021 gtacgaccac ataaccatct gggcaagtca ccgacacttc cctatctata tattcgttag
    25081 aagcgtacac ttttttaaag aaaaaattct cctctgtcaa ctcatactta gctccaagaa
    25141 tagtcagctg gctatcccga actggcataa aggctagata gtcgtagtct gaacgaggtt
    25201 ctagctgact ggtcccttct gaacaatagg caatcaaatt ttgcccatcc tcaatttcta
    25261 tttgacgcat atagggtgcc aacttaggat tgctaggtag aaagacattg gccaacatat
    25321 ggtcaatacg gccacccaag gcaccgaaaa tagtgacctc agcctgagga ttttgttcaa
    25381 agatggttaa gagagccaat tccagatctg tatcatcctt ttctggtcgg gcttggacaa
    25441 aatgctgggc acgtttttga atcacctgtc gctcttcttc cgtcacagaa tcaaaatccc
    25501 caactgctag agcaagaagc aagtcttctt ccaagaccca gagcgagcct cgatccaccc
    25561 caacaaaagc atcaaaatct gtccgataat gaccgcggtc tccgcctgca aaaacggcaa
    25621 ccctagtcca gttgttttct gagagtttgt actcgctcat tgacatctcc cttaaagaca
    25681 taggaacctg ctacaaaaac ggtcgcacca gcttctttag cttgggcaat agtttggtca
    25741 tcaatcccac catccacttc gatttcaaag ttcaaacctt tttcctcacg aagagcaacc
    25801 aactcacgaa ccttatccat ggtttctggc agaaaggctt gcccaccaaa acctggatta
    25861 accgtcatga ctaaaacttg gtcaactaga tgaaggacgt gcttgatggc ttcaactgat
    25921 gtgccaggat tgataacgac tgaaggctta actccgagtg aacgaatttt ttggagggcg
    25981 ccatgaatat gaggcgttgc ttctacatgg atactgatga tgtctgcacc tgcacgcgca
    26041 aaatcttcca gatgatgctc agggtttgac accatcaagt ggcaatcgaa aaccatctta
    26101 ctatgaggac gaaggctctc gaccacacct gcaccaaaac tgatttgcgg tacaaaatga
    26161 ctgtccatga tatcgatatg ggcatattct gccccagttg cttctagacg tttgatttca
    26221 cgttcaaagt tggcataatc tgctgccaga attgacggag caatcttgta ttgagacata
    26281 ggtttctcct tattttggaa tttttttgct gactttttta taggtttctc tacgattttc
    26341 aatttcacta aggaattgca ggtaattgtc aaaacggaag gttgcaataa caccctcttc
    26401 aacagctggt ttgacggcac aagacggctc atgggtatgg gtacaagtac ggaacttaca
    26461 atctcggcta acagtagcaa tctctgggaa agcctgattg aggtcttcag cccttgatac
    26521 ttcatagtcc aaggatgaaa atcctggtgt atctgcgatt ttacccccgt tgagattgta
    26581 aaaactaaca gctcgagtgg tatggcgacc gcgacctaga ctgtctgaaa tttctcccgt
    26641 ttcaagattg aggtctggtg cgattttatt gagaagagtt gacttcccaa cacctgtctg
    26701 ccccataaag accgtaacct tgcctgttaa caaagacagg agttcctctt tactggtcac
    26761 aaagtcatag ccgatgtcac cataggtctg ctggtaaaaa tccagttctc ccctatcttc
    26821 caacaaatcc attttggaaa tatagacaat gggatggatg cccttgtgct ccaaaagaac
    26881 caagaaacga tccagcaaat tgctgttaaa atcaggttcc ttgacggaca tgattactac
    26941 agcttgatcg atattgacaa taggcggacg aaccagactg tttttccgtt cgtgaatttt
    27001 gaggatatag ccttctgaat tttcctcggc agagaaatct acccagtccc caacataagg
    27061 ggtatggcct tttttacgga aattcccacg cgcgcgtgtt tgataaacct ggccatcact
    27121 ctccacatag tagaaacctg ccaaggcttt aatgatttgt ccctgcatct tagagtcctt
    27181 gccctttaag tgcgtctgct agaccggcaa attctgccaa gctgagagct tccccacgca
    27241 cacttggtga caagcctgcc tggtccaaag ccttggtcag cttgtccttg acctcttcag
    27301 tcttaccaaa gtaacctgtc aagttattcc acaaggtctt gcggcgatgg gtaaaactag
    27361 ccttggaaac cttaaagaaa aagttctcat cttctactgc tacggctggc tctggacgac
    27421 gcaccatttt caagatggct gaatccacat ttggcgctgg cacaaagacc gtacgaggca
    27481 cgataaaggc aaccttggct gtcatgtaat actgcacggc gatagacaag ctaccgtaag
    27541 ccttggtgtt aggctgggct gaaatgcggt ccgctacttc tttctgcatc atgaccacaa
    27601 actcactaaa aggaatgcca ctctcaatca agtgcatgag aataggcgtc gtgatgtagt
    27661 aaggcaaatt agccactacc ttgattggca ggttaggatt tttaaaattt tggatatgtt
    27721 gcgccaaatc aaccttgaga atatcttcgt taactacagt cacattatca aaatcacgca
    27781 gggtatctac caaaattggc accaaacggt ggtcaatctc aaaagccatg acttgggctg
    27841 cacgctcagc cagaaactcc gtcaaggcac caatacctgg cccgatttcg atgacattga
    27901 cctggtcatc aatttcagcc gtatccacaa ttttttgaag gatattggta tccgtcagga
    27961 aattttgccc gaaggacttt ttaaaggtaa aaccgtgacg ctccagcact gccttggtca
    28021 cgctataatc tgcaattctc atctattctc ttttctatta tctgttacta ctattgtaac
    28081 acattcccct tgtattttgg gaatgaaaat cataccaaaa aactatcttt cctcatgaag
    28141 aaagatagtc ttggaaatct ttaaaagtgg ccttaacagt tctctcgaaa catgcgttca
    28201 tactcttcga aaatctcttc aaaccacgtc agcttcacct tgtcgtactc aagtacagcc
    28261 tgcggctagc ttcctagttt gctctttgat tttcattgag tatcaaaaaa atcagcttct
    28321 tgataacttc tattttcggg tagggtcaaa tccacatcct cctccacatc atccactgtc
    28381 agttcaaccg tttgaggtaa atttttcaaa cgataatgct tttgccttta cccttcaata
    28441 ctagcaaaat caagcaaata gccatgcact aggatttgaa ccaaaaggag atgattggtc
    28501 atatttttat cttctaaacc acctctggca ctaggataat cagataccct gcgaatacgg
    28561 attttttcac acatgagcaa gtttcctcat atcaatgatt tcatcagcct tattccagac
    28621 taggggatta tgggtcgcaa tgatgataat tcgattttca tctttcaaat ccaccaagag
    28681 attcataacc tcctctgaat tttcaggatc aagagctgct gttggttcat ctgccaaaat
    28741 caagggtgga tttttcaaaa tagtttttgc aagggcaact cgttgggcct ctcccccaga
    28801 taaagtatag attttttgtt ctaaatccaa ataccctaga ttaacttttt ctaaagcccc
    28861 cacttgcctt tccaaacgtt ctacttttga gattttctga ccaacaaaac ccaaatccaa
    28921 attttctttg attgattggt tttctaagag gccgaaattt tgaaagagat agcccatctg
    28981 gtctcgaaaa tactcacgag taggaatggt ttttaaatct ttcccctgat agagaaccct
    29041 tccaccatct atcttttcta gctttcccaa gatattcagc agcgtcgtct ttccgcttcc
    29101 actctttccg attaaggcat aaaccttgcc cttctccagc ttgagattca aaccagagaa
    29161 aatcgcgcgg tcattaaatt tcttttccaa tccttgaata tcaatcatct tattttcctt
    29221 tcaatactgc catgctacca gcttcttctt ttttgtcctg ccttactaaa atcaagaggg
    29281 cgttaagcgt aaacaaagct acaactagag cgctaatcaa accatctctt gtcaaaatac
    29341 tagataggac taggccaagc aagagaactc ctccttgcgc cagtaaatac ttgccatgaa
    29401 gttcatagat tgtcatacca gcaagacgtt taatcataag ctcccgtctg aactgctcaa
    29461 aatagagaag attcatggaa tcaaataaca agatagccgt agacagggtc aaaatcgtcc
    29521 caataaggag agagtaaaac tccacccgtt tgtcatttag taccttggca aaaaatagct
    29581 ggctttttac caagtaagaa accttgtgat acagaccttg ctcttttaga gctgtgatgc
    29641 tgtctccata tcgatctagt ttcaaggcac tattagccgt agttccccac aacatccctg
    29701 caacaggtct tgttccagtc gcttgcggcg ttagaactac aataatcgga tcttttaggt
    29761 actggcgtgt tgtcttgtac ccatcattat agaggaaacg ttcctgtcct gtttctgtaa
    29821 aagctagcct tacctgtggg aggtagtgtt tctgactcgt cacttctaca ctttcagatg
    29881 aaaagttttg caggtaatct gtaaacaatc cttggtagta gacagactgc tctcgcaagc
    29941 tctcaggcaa gatcagccca aactctccct cagacaagtt ttgcatcttg tccataaact
    30001 ctgaagaaac ggtaatcttt tcttctatca gatagcgtgg tgagacatag ataacattcc
    30061 ctgacggtgt gtagtcactg agacgattgc catctaggtc cacttctgct ccatctgaga
    30121 aattgtcaac attgctcata atataaaaag agtctgtatt ggctaaccgt tcttcagtaa
    30181 atgtctgcca ctcacgatta tccttacgcg ttccttcttc atcggcaaat gcactagacc
    30241 aaccaaagga tagacggtaa cggtctgagg actggctcca tttattgcta gctctctcca
    30301 tttcctgcat ttcacggtag tggggtagga gagctgtcgc actcgatccg accaccaata
    30361 cagctaagag ttgccccacc atcatcaatg tcatcatacg tttgagaggg agtttccctt
    30421 tcaatagatc caccagacta ttttcctgta aaccaagtag atagacgaca cttagtaagg
    30481 tagaaatccc tgccaaggtc aatccataaa gtagaagagc aatgatgacc agttgcaccg
    30541 ttgccataaa caaggcacct tgataccaga gaatccccaa tcccaaaaga ctggatacca
    30601 gcactgagca gataagctgt ctcacatctt ctaacactgg tctgagagca actccaaaca
    30661 agctctcacc agctattaag cgaatccctg cctgacgaag ggatttgatc cgataaatca
    30721 gggtcagact cataaaggtc agcagaaaaa tagctaaact cagtagcacc ataggggtgg
    30781 ccgtcaatag taagactatc gaaaatggat cttctccatt cgaaacaaag ccttgataac
    30841 caagctcttt caaggtggtc tgtaagctca ctccatccaa acttcctgac acaatcaagt
    30901 aagaccctaa taaatcactc gtttctgcac tctccttgga ggaaatggtc agaccttctg
    30961 gaagctttcc ctcaccataa gtggcatagg taaagcgtgt ttctccagct tcatttggct
    31021 caacgattcg acgagcaatg agactattgt gctctaccgc caagtgactc aaagcctctg
    31081 tcacctcttc ccgactagct actggttgat ttatcatcat tcctgtcaca tcaacagaag
    31141 gatagttacc aaataaaatc tcttctcgat ggtcaacgga agttatcacc atataaagcg
    31201 ataccaatac cattgaaatc aaaataaata aacgtttcat catttcctcc aaaaagttac
    31261 ttggtcactt agtgagaagg tgaccaagta aagctaaaca atagggctat accattctaa
    31321 acattatagt agaatgcaac tttctctccc caagaagtac gaatccatgc acgagaagtc
    31381 cctccagcac cagcatatcc cttgtcagat gaaccagttt ttctgctaac aactgttgaa
    31441 ctatggtatt ttgaagggtg atagtagttt gagtaagcac caccgttacc tgaaccataa
    31501 gtccaaacac caccttctgg gtattgaacg gctgcagagg caactgctac acttccacct
    31561 aatgttgctg caatgctcgc tacaagagct aattttttaa ctgtttgttt catattgata
    31621 ctcctctatt tttgattaca agattgttga gttacttgct cctctttcca ttatcaacgt
    31681 tgatactatt atattaccaa atgatattct aaaattattt gtttttctct aaattgtcaa
    31741 aatagcaccc tgaaatgaac ttttatagtc attatactcc atctttatca cactatcaag
    31801 gacatcaatg tccttaaaat ctaactattt catattattt ttagcttata tctaaaaaaa
    31861 cagttctaaa gacgaacttt agaactgttt tgatacgagg acaaggacat ttttgtcact
    31921 gattcactat gtttataaat attttttgac atcctcttgc cattcctctg tcaatttctt
    31981 tactagaaat ccatctccaa ttagcttcgc aaatgtttta gaagactgat aaaatgattc
    32041 agctaaacta aaatctcttt ctactcttaa tgcttgcttc cacaaaaaca taaatacaag
    32101 aggtttcttt tgataatctt gagttttatc cataatttct tgtaaacacg atagataatc
    32161 attaaaacaa tcagttactc ctaccttttc aagacaacac attcctgaaa taagagtatc
    32221 tctaattata aagtaattct ctatttgagt taccttcttc tgttccaaaa gaaagagcat
    32281 tagcttttcg atttgattta taaatttggc aagatctttt ctaatgagca tttgataaaa
    32341 aaacaaacga atcaacaaca tatcatttat tgaataagct tctttttcta taatctgagg
    32401 catatgttcc tcaagtatta actctgcata ttcaggcctt ctagttctag aagtatccaa
    32461 acacgcctgc aatacttcac atgctaattg ttcttcttta ggaagattat caaagtatgt
    32521 tttataaatc tcttccaaac acgcttcctt cttatcgtac tcctcttctt taccatagat
    32581 tggttcacgt aaaatctggt atttcaattc taaataagca gaaggaagag ctgaaaaatc
    32641 cggcataagg ctataaactg gaactcctag ccggcgagca atataggcta acttgggcaa
    32701 actcggttgc gaagctccac tttcaattcg cgacagttga cgaactgtca gttcttgctc
    32761 atctccacaa aaatctggac gactaattcc tttttctatc cgaatctctt taattttttg
    32821 accaattaac atcagacgcc tcctcttcta cctgcttcga aaaatactgt gaaacttaaa
    32881 aaattgtaac ggctacatct ttcctactca taagatttca tagcttcttc cacttctgcc
    32941 aaagtaaccc caaacaactc taggcgtttg aggagttgct tgccgttaga atagccgatt
    33001 cggagagtct ctccgagata ttctctacgc ttacggctgt ctgcccctgc tagaaaacca
    33061 aggcgaatca aatcgctacg actaatgtca aactgactct catgttcaaa ttgttctgtc
    33121 acctgagcta gagccgtttt caggtcttca tagctggcat gctcaattcc cagagaacgc
    33181 cccttggtct tggacttggg aacagcttca tctcgcttga gaaaggcatg ctgaactgtt
    33241 ggaatggccg tcataatcat gcgccgaatc cgctccccat taaaatctgg gtctgtaaag
    33301 acaatgactc catgacgttg gtgtagacgc tgaatccgct ctatgtcctg gtcattgatg
    33361 gcagaacctc gagtctcata ggtctccaca tcgaaataac gcttgagatt gaccgtatca
    33421 tcacgacctt caaccacgat aacttgggaa attctctctt tcattacttg ctgtccaatc
    33481 caaaaatgcg ttctgcattt gcagtcgttg ctaccgccag ctcttctgtc gtcataccac
    33541 gcaagtcagc gataaagtcg accacatagc gagtataggc tgttttattt tcacgaccac
    33601 gcttgggtac aggtgctaag taaggcgcat ctgtttctac caacatcttg tccaaaggta
    33661 actctttagc tgcttcttgg aggtcagttg ccttcttgaa ggtcaccact cctgagaagg
    33721 aaatggtcat accaagatcc acaaacttct ctgcccactc aagcgtccct gaaaatgaat
    33781 gcatgatacc accacgagga ccaacgccct cactcttgat aatctcatag gtatcttcca
    33841 gcgcatcacg ggtatggaca acaaaaggca aatccaagtc cttagatagc cgaatctgac
    33901 ggcgaaaaac ctgctcctgc acctctttgg gcgctgtcat ccaatggtaa tctaagccaa
    33961 tttcacctaa agccacaacc ttgggatgtt ttaacttatc caacaagtaa gcctcaactt
    34021 cctctgtata agtaccagct tctgtaggat gccaaccaat agtcgcatag agctgctcat
    34081 actcatctac caactccaag gcacgctcaa tcatcggttt atcaaaacca acaatattca
    34141 tctgtatcac acccatctca gcagccaagg caatttcttc tgcctcacga cctgcaaatt
    34201 cttctacatt caagtgtgta tgtgtatcaa aaatcatctc ttctaacctc gttttctatc
    34261 ttctattata ccaaaaaaga ggaggggcac ctaatttttc ggtttcccct cctctcttca
    34321 atagagagct attctgctat cttttctatc cgatattgcc catctcctat tccacagtta
    34381 gagacagaag agattggcta cattgataga atattcctat tcagctaaag tatgtgatta
    34441 tcttgggttc tcacttttct cacccatcac taggattgat gacttctcaa aatccccctt
    34501 ataatctaac tttaagtaga gaatagaatt ttctagctgt tctattttct acgtctagtc
    34561 tttcttccta gcaaagcaaa accacttgtt gccaccacta gaccaagact agcaagtgct
    34621 gcacttgatg ctgaacctgt gttaggtaat tgtttgccag caggtgactg gtaggtaaca
    34681 tcttgcattg ttcctgcagt tgcttgcggt gcacttgttg tcttaggagc agcattagga
    34741 gccactagtc tcttaggaac tgtaaccatg gcaatggctt gcactccaat cgtttctgct
    34801 tccttcacat cttccatagt tttcgcattt tcaatctctt tgagagctgc ttgtttttct
    34861 gcttccactc ttgctaaaag ttctgctttt tctttatcag aaagcggtgc gcctttgatt
    34921 tcatcctgct tgtccttggc tgctttttca atggcatttt tagctgattc tttttcagta
    34981 gctaattgct tagaagcttg tgattgagct gagttttgtg aacctgtgtg agctgatcca
    35041 cccgcctggc taccaccgcc ttcattcgca ttagcatctg agcttccaat attgcctccc
    35101 ttatctccac ctggtgtagt ttctagctta tactctggtg taacttcttg agttacagat
    35161 tcacctttcg cagattgttg aactgtatct tttcctagaa tcgtcactac tgaaccatct
    35221 gggaatgtga ttgttgctgt accatctcca gctacattga ttgtcgctcc gtctaatgct
    35281 gaaccatttg cttgtaaaat agcaacctta actttttctt catctgttaa atgagttata
    35341 tcttttacat ctactctttg agcaggtgct ttaacagttg atttttcagc agtcggttta
    35401 gtgctatctt gtgcttttgg atcttgtgct accaattgat ttcctggaat tgtaatagct
    35461 gaaccatctt taaagacgat tgttgctgta ccatctccac ctacttcaac tttatagtaa
    35521 aataaaataa taacaggaca aatcgatcag gacagtcaaa tcgatttcta acaatgtttt
    35581 agaaacagag gtgtactatt ctagtttcaa tctactataa catcgcttcc gaatccattt
    35641 gcatctactg aactttttta caaaaataaa aatcagtaga ctcgagttcc tactgatttt
    35701 tgatagaatt cgtttggatt atgcagccaa aactttgcgt cctttacgac gacgagctgc
    35761 caatacgcga cgaccatttt tagttgacat acggttacgg aatccgtgtt tgcgcgcacg
    35821 acgaagttta cttggttgat aagtacgttt cacgatgaat acctcctcat agattttgta
    35881 ttcgtttagc cggctataaa gtgatcagtt actaaacata ctttactatt ctatctgatt
    35941 ctttcacttt tgtcaatagc tctaggcaaa tgtttccagc tttttcgaat gcaagcccta
    36001 tctacgatac tgtttcaaga aacgagtcat cttttcttgg atttgggcta actcatcaac
    36061 acgaggaagg taaacgatac ggaagtggtc tggttcctgc cagttaaagc ctcgaccatg
    36121 aaccaagaga accttttcct gcttcaagaa atcaaggaca aactgctcat catcatcgat
    36181 acggtacata ttgcggtcga tttttgggaa gatatagagc cccgccttgg gtttaacggc
    36241 agacaaacct ggaatatctt gaatggcatt atagatgaaa tttctttgct cgtagattcg
    36301 tccaccagga agaagtaatt catcgactga ttggtgaccc cccaaggaag tttgtacgac
    36361 ttgttgggcc aaaacgttag agcaaaggcg catattggac agcatattga gcccttcgat
    36421 atagccctta acatgagtct tagggccaga caagaccatc caacccacac ggaaacctgc
    36481 tatgcggtgg gattttgaca gaccattcat gctgacacag aagacatctg gtgccaagct
    36541 cgccacaggc gtatgcacat gtccgtccat taccatgcgg tcatagattt catccgcaaa
    36601 gataatcaaa tcgttttgac gggcaatctc aataatctcc agcaagagtt ccttaggata
    36661 aagggctcca gttgggttat ttggattgat aaggacgatt gccttggtat tggaagtgat
    36721 ttttgacttg atatcgtcaa tatctgggta ccattcaaca gcttcatcac agatatagtg
    36781 aacggcattt cctccagcta ggctgacagc cgccgtccat agaggatagt ctggcattgg
    36841 cactaagacc tcatccccat tgtccaaaag cccctgcatg gacatgacaa tcaactcact
    36901 gacaccattt ccaaggtaaa tatcatcaat atctacgttt gggaatttct tcatctggca
    36961 atactgcatg atggccttac gggctgagaa aatccctttg gagtcagaat agccttcact
    37021 atcacgcgca ttcataatca agtcatgaat gacctcgtct ggcgctgtaa agccaaattc
    37081 tgctggattt cctgtattca gacgtaaaat cttttctcca ttcgctcgca tccgcatggc
    37141 ttcttccaat acaggaccac ggatatcata agcaacatgc tctaacttac tagacttgtt
    37201 atattctttc atcttgtttc ctcaattcat caggatagta acattatacc actagaaaga
    37261 gaatgcgaca agtttactga aatgtgttac tagtttcgta tagaagaaaa accttgctaa
    37321 aggcgaggtt aagaacgtag agatagcagg tattttgcaa agacacatca cataccaaaa
    37381 gataaaccta gaaaaagcaa gcctagaaag gagtcataaa gaagattaaa catgaggaaa
    37441 agcccccata tcatcaagta atcccaacgc ccacttcgtt ttgcaactag aaataagatt
    37501 agatggtaga gtacatgaaa gactaaaaat ccaataaaac ttggataaag aagcggtacc
    37561 agactctcta attgacagat catgatcact tttaccaaga ctgaaactag gataattcca
    37621 taataaagga aatttgattt ttgaaaagag tttttcatca ttctcctttc ctcctatcct
    37681 ttcttttatt ttatcatata tttatataga gtttaagccc taatattctt ttgaaaaata
    37741 ctttttttgc tttacttcta tagtgaaaag gtttacaatt atagtaagaa aatttcagga
    37801 ggtttcatta tggcacaacg ttaccaaaat atcatggtcg caatcgatgg ttctaaggaa
    37861 gcggacttgg cttttgtcaa gggagttcat tctgctctac gaaacgacgc taaactcacc
    37921 atcgcacatg tcattgacac acgcgctctc caaagcgtat ccacctttga tgctgaagtt
    37981 tacgaagaac tccaagtcga cgctgaaagt ctgatgaaag agtacgaaaa acgtgctaaa
    38041 gatgctgggg tagcagatgt tcatatcgtc attgaaatgg gaaatccaaa gaccctgcta
    38101 gcacgtacta ttccagatgc cgaggaagtg gacctcatcc tcgtgggcgc aactggtctc
    38161 aacgcctttg aacgcctctt ggtcggctct tcatctgaat acatactccg ccatgctaag
    38221 gtcgatttgc tggttgtgag agaacaagaa aaaaccttat aatcacaaag aaaaggagcc
    38281 cctagctcct ttttgtttac gatttatttc tctctttatg gcgttcgtaa gccttgagct
    38341 ggcgatgcag ttccttttta atagcaggtt ctggagcata tttttcttcc caattatctg
    38401 gttttaagat tttatgggtc actggatcaa aatgagcctt gccatctgga aaaattttcc
    38461 ccatattggc ctgatggaca atatcaaaaa tacgttctgg gtccaccccc atcaagacaa
    38521 aactgccgta ggtgaagtaa agcgtgtcaa tcaaggcatc cacttgccct atcaaatctt
    38581 gctgagcagg tgtcttcttg gctactttac ctgctgcctt atcaagggcc tgatgaagtt
    38641 gcgatacagc ttgaccaaaa tcttcttcag aaggactggc tgctcgaaca aactccacca
    38701 attcttctat tttaaaacca gccctatggg ttgcaccctc taaatcccaa gctcgaggtt
    38761 cttcttgggt tcgttcatcc atcatgtggt ggaaggtctt gaccttattg aaatgatagt
    38821 cacggctgac aaagactttt tctgaagaca aaacaccaaa atgttccaag gccttgtgga
    38881 tcccatcttg ttgattgcta gtggtaatgt gcttggcagc ttccttgaca ctgctactac
    38941 catttcccat agcgaccgac ataccgacgc cagccagcat ttcaaggtca ttatctgagt
    39001 caccaaaagc catgacttgg ttgaggtcaa agccatattc tttcccaact cggcgaatgc
    39061 cttctaattt agaatttccc tgattgatga catccgatgc aaaaggattg ctacgtgtca
    39121 atttcaagtc ttcaaaatca gctgccgcct tctcagattc ttctggtgtc atcagcatca
    39181 aaacttggta gataggctga ttcatcaggt gaagcaggtc ctcttccttt tggggaacaa
    39241 ccttgctgac catgcgatta aaagactgac tcaccgtccg agttaaaaca gagggaacga
    39301 agcgactaat tcgttgggaa aaagaaccca gaccaaagga catgatttta gaacccaaca
    39361 tggcatcctt ggtccctaga gcaatctccg tgccctcttt tttagcatag ctaattagat
    39421 ggcgcaaatg taacttggaa atagggctcg tgaacaagac tctgtcttta ctaaagatat
    39481 actggccatt ataggttacc gcaaaatcca gatccaaatc gtccatcaat tccttaacaa
    39541 aaaaaggtcc tcgccctgtc gctacgccaa ctagtacccc ttgttctttg acaatcttaa
    39601 tcgcgtcctt agtggatttc aaaacactct tgcgattgtt gaccaaggtt ccatcgatat
    39661 caaaaaaaac agctttgact tccatcctat tccaatctcc ccttttgtga tacaatgatt
    39721 ataccacatt tcagaaagag tgagtaaatc atgcctaaga aaatccttgt tttacatacg
    39781 ggtggaacta tttccatgca ggccgatgct tctggcgctg ttgtgacgag ttcagataat
    39841 cccatgaacc atgtgtccaa cccacttgaa ggaatccaag tccacgcctt ggactttttt
    39901 aaccttccaa gtccccatat caaacccaaa catatgctgg tcctctacca gaaaattaaa
    39961 gaggaagcag ataactacga tggagtggtg atcacacacg gaaccgatac tttagaggaa
    40021 acagcctatt tccttgatac catggaagtt ccccatatgc ctatcgttct aacaggagcc
    40081 atgcgtagct ccaatgagct cggtagtgat ggtgtttata attacctaag tgctttacga
    40141 gtggccagcg atgacagggc tgctgacaaa ggagttttgg tcgttatgaa cgatgaaatc
    40201 cacgctgcca agtatgtcac caaaacacat acgactaatg tcagcacctt ccagactcca
    40261 acacatggcc ccctcggtct caccatgaaa caggaaatcc tctacttcaa aacagctgaa
    40321 cctcgtgttc gctttgacct tgatcacata caaggtttag tccctatcat ctcggcttat
    40381 gctggtatga cagatgagct gattgatatg ctggatttag aacacttgga cggtttgatt
    40441 atccaagcct tcggagctgg taatattccc aaagaaacgg ctcaaaaatt agaaagcctt
    40501 ctgcaaaaag gaattccagt cgctctggta tcacgatgct ttaacggtat tgccgagcct
    40561 gtttatgcct accagggtgg gggcgtacag ttgcaaaaag caggcgtttt ctttgttaaa
    40621 gaactcaacg cccaaaaagc tcgcttgaaa ctcctcatcg ccctcaatgc cggactaaca
    40681 ggacaggctt tgaaagacta tatggaaggc taatactctt cgaaaatctc tgcaaaccac
    40741 gtcagcgtcg ccttaccgta tgtatggtta ctgacttcgt cagttctatc tacaacctca
    40801 aaaacatgtt ttgagctgac ttcgtcagtt ctatctacaa cctcaaaaca gtgtgttgcg
    40861 cagcctttaa ccagccgcct agtccgctct atggtattca ttaagtcaac atctcttgtt
    40921 taagagcaca aaatcaggaa atcttctcga ttccctgatt ttttctattt acgttttcgt
    40981 gttgagctac gttctgtcaa accatgaggt aagagaactt cacgttcttc caactcttcc
    41041 ttatgcataa tcttggtcaa catacgcata ctaatggcac caaggtcata aagaggttgg
    41101 gcaatcgttg tcaagtttgg acgggtaaag cgtgagattt gtgaatcatc actagtaata
    41161 atttcaaaat cttctggcac agaaacaccc ttatcagcca aaccgttcaa gactcctgct
    41221 gccaactcat cacctgtcac aactgctgca gttgcatttg atgaaatcaa acgctctgct
    41281 aaggcgtaac catcatcata gctatattta gattcaaata ccaaaccctc actataagtg
    41341 attcctgctt ttttcaaggt ttccttgtag ccaactaaac gaaccttacc attgatgtca
    41401 tccactagcg gaccgctaac gaaagcaata cgctcatttt ctttagcaag gtaactcact
    41461 gcatcaattg ttgcttgctt atagtcaata ttgacacttg gcaactggtg ctcaacatcg
    41521 acagttcctg cgagaacaat cggagtacgt gaacgcgaaa attctgagcg aattttatct
    41581 gtcaagtgat aacccatata gataatgcca tctacctgct ttgaaaagag ggtattgaca
    41641 acagaaactt ctttctcgtt atcttcatcg ctattagcta ggacaatatt gtacttgtac
    41701 atttctgcaa tatcatcaat ccccttagcc aaactcgaaa aataaccatt ggtaatattt
    41761 ggaatcacga caccgacagt ggttgtcttt ttacttgcaa gaccacgcgc aactgcattt
    41821 ggacgataat ccaaacgatc aattacctct agcacttttt tacgggtatt ctcttttaca
    41881 tttttattgc cattgaccac acggctgacc gtcgccatgg aaacacctgc ttcacgagcg
    41941 acatcataaa tggttactgt atcatctgca ttcattcctt ttcctgtcct ttctatctca
    42001 cacattcttt tacaagtaga ggtactgatt gaagctctat atctacttac aaaagtgaag
    42061 atgtgaaaat ttcgttttca tatttctact tattccattc tatcactaat tgtaaacact
    42121 ttcaagtgtt ttttgaagat tgattgaaaa aatttcatag aaaacctagg tttagctcct
    42181 tgctaccacc ttagactaaa caaaaaggag gaaactaagc cctcctaaag ttatagtaaa
    42241 atgaaataag aacaggataa atcgatcagg acagtcaaat cgatttctaa caatgtttta
    42301 gaagtagagg tgtactattc tagtttccat ctactatagg tattgttcca ttcactaccg
    42361 tcaattttag cacatagtct tcatgaaaat attatatcat cataaccaac cagattcttt
    42421 tgcgatatta gctgcctctg ttcgattacc agcatccagt tttgaaagaa tattggtgac
    42481 atagtttcga atagttccgt ttgagaggta aagctgatct gcgatttctt ggttggataa
    42541 gccccgggcg attcccttta agacagcaat ctcttgttct gtcaacggat tgggacgggt
    42601 catcaccact tccatcaatt caggcgaata ctccttgcgt ccttcgagga cggtgtgcaa
    42661 ggtttgcatg aggtctgcaa tgcttcgttc ctttaataca taagcatcca ctccagcctt
    42721 gaccgcacgt tcaaaatacc cagcacgctt gaaggtcgtc accacagcca cctttgtttc
    42781 aagcctttct gatcgtatcc actccaagac ttcaagacct gtcttaacag gcatttctac
    42841 gtcaaggatg gcgatatcta cagactcctt ttctaatagt tggattgctt cttgcccatt
    42901 cttggcttga aggacagact ccacatctgg ttgaagcgtg agcaattgac acatggcatc
    42961 tcgcaacata ctttgatctt ctgcgactaa tactttcatc ttagtttctc tccttataag
    43021 gtagtcgaac ttgcacttcc gttggatgtt tctgactgat tacacttact tctcctgaaa
    43081 atggaaaaac acgatctcgg actgtatgga gctcatctcc ttttagaaaa gcaaagccgc
    43141 agccatcatc acttactgtt aaaatgagtt ccttctctgt ccgttctaat tttaagtaag
    43201 ctttagacgc tttggcatgt ttgatgatat tggtcaccaa ctcaagcaaa atcatagaag
    43261 ccattgaatc caattcttga gtaaggctag cagtatctag ttggttatct gtttccacct
    43321 caattccagc aatttctaac atctttttca cagtctctag ttcggatgtc aaagttctag
    43381 acttaagatt ttccacaatg gttcgaactt cacacattga ttctttgcta atttgctgta
    43441 tttctcttaa ttccttttcc acttgtggat aagcctgcat ttgaaatagc tgcaaggcta
    43501 gatctgtctt gacactaagc atagcaaagg tatgtcccag actatcatgc aaatcctgac
    43561 cgatacgatt gcgctcattt tctgctagca atagatttat ctgggtattt tgcttgacct
    43621 gagcttcttt caaatcctcg acaaggcgaa ttcgaaccga gcccaaagtc atcaaatcga
    43681 caaaagtaag aattacaagc atatagacta gaaactcaac ttcgattctc tgaaaaatca
    43741 aaagtcgccc cacaacaagg acttgagcaa ggagaaatgt ccatacatgt aaagacttta
    43801 aactacgtac gccaaaatga taaattaaga gattggaaag gaaaaagaaa aaccagatat
    43861 aattcccagc aacaaaggcg gtattcccag ctacatagac cagcatgagc ccccagaaaa
    43921 gccaagatag gcgctggttc ttagttatta aaacacccaa atacgtcact acaaatagaa
    43981 tatcaaccaa taaatgccaa gcaggaagct ccccaatcac tacaggtagg atgggaaaaa
    44041 gcataaaaat caaactggtc caaaacatat agtgtatgct tttcagtctt tcaagcatta
    44101 agcattctcc ttatgacctt gaaggtaaat agtcaaacca aataaaactg ctgaaaaaac
    44161 aagtaaataa actgtggctg atagattgat gtcaccctcg tttaagaagg tcttgagcaa
    44221 ctccatcaat tgataggtcg ggagacactt accaactgct tgcatccagt ctggaaataa
    44281 agaaatgggc atccagagtc cgcctaaaac agccaatcct agataaagaa gattgcccac
    44341 aacagacatc agctgactag ttggtaagag agtcaaggtc aagccaagtg ctacaaaagc
    44401 aatactcccc acaatcagca aaatcgcagc tccaacccat tttactagag gcatgtctac
    44461 acctcttaca aaatgtccaa ctgtaaaaac aaccagaatt gagaccaaat aatcaaccag
    44521 catacttgtt atctttgata gataatattc taccatattt acagggctat gacgcaatgt
    44581 tttctgccag ttgttcatct tatcggtatg taaaacagct ggaaatgaga ggatagttgt
    44641 cgacatcatg gaaaaggcag tcatggagat gaggtaatca cgcataaaat tcgcgagttc
    44701 acctggtgtg tcctgataga taccagaaaa aaataaatag aaagccgtcg gcatccctac
    44761 cgacaataga taatagatta attgtcgttt ggtcaataaa aattctatct tactaagtgc
    44821 tatccatcgt ttcatcttag ttatctccct tctgcgtctc ttcaaagatt gtattcaaca
    44881 aactacgatt attaacttcg atttcttgca tcctacatcc tgcttgggct aatagttccc
    44941 agaaagcatc tgcttctcga gtgactactt gtaaagaatc ttgctttagg gtccagtttt
    45001 caaccaaatt tgactgctct acgacttcct tgtaagctat aggaaggata aagtgctttt
    45061 ctatttcctc gctacgcata gctagaggcg tcgtatctcg aatcaactct cccttattta
    45121 agagcaaaat gcggtctgca gtgtgttcca cttcctcaat ataatgggac gaatagagaa
    45181 tggtaactcc ctgcgctttt agatcctgaa caatttccca aaaacgttgg cgggttgagg
    45241 tatccatggc cgcagttggc tcatctaaaa agacaagttt tggtcggcca atcaaggtca
    45301 agacaaaaga gaaaagacgc ttttgcccac ctgacaattt ttctgccaat tgctctttct
    45361 gttgcttgtc aaactgcaac agttgatcga tttcctggtt gctcaaggga tttggataaa
    45421 tgctttgaaa gaaagcaacc aactctttga cctttaattt ctgaacgatg acattttctt
    45481 gaggcagata acctctaata tagtctaact gagaactcgt cactgacaag ccttggatgg
    45541 atacttgacc gcttgtgacc agtttatctc caagcagaca gtccaagagt gtggtcttcc
    45601 cagcaccatt tggcccaatc aaggcgacgc attcaccttc agctacctca aaggaaatat
    45661 ccttcaaaat agcctttccc ttgatgtttt tatgtaatcc ttgaacctta atcatgtcca
    45721 tgatattctc ctttcaacca ctccattccc ataggaaagg cgataaaaat cataaatcct
    45781 agtccccagg caccacggat gaattggcga agcaaggctt gatcaaacca acctgtaaac
    45841 atttctacca accataccac tagtgatagt ccaataaaaa gatagagaaa cgcttttttc
    45901 atttttcaaa ctcctttttc acatctgaga ctaatttcaa accttctcgg ataagccagg
    45961 acatcattcc aaatcctgca aatagctccc aaggaaaatg atagaaatct tcatccaatc
    46021 ctgagaacat gagataagtc atgactcctg ctgctactaa actcattgcg acaatcattt
    46081 tatttttcat ctcttcttcc tccgtttcat acttcaatta tagacttttg aagttggcgg
    46141 agctagatgc ttctgtcact agaaaatatg acaaatgtca taaaaattct gtacaaaaca
    46201 agcaagatac actatataat aaaacacaag tagaaaaaat ctaaggcagc tttcaaaaga
    46261 gatatcaaac ccaattcaca ccataatgta aactaatact tatttaaaat caaaaagagc
    46321 ggaaattttt atcgcacaaa cacatatatt ataagcagag cgaaaaactc ttcaattact
    46381 ttcttaaaag tttgtaagaa ttatacaatc tgttaaattt taatttatgt acctaaacta
    46441 cagtattcat tgaacaaatt aggaaacaaa aaagtatacg ctgctaaaat gaattactga
    46501 aattcaaaaa agagagaagc aaactgattc tctcttaatg tatataatat ctagttaaaa
    46561 caaaaagata cgcttacgta tctctgaaa
//
LOCUS       DAVHKZ010000013        44577 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000013 DAVHKZ010000000
VERSION     DAVHKZ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44577
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.013"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(115..330)
                     /locus_tag="VVO74_000888"
     CDS             complement(115..330)
                     /locus_tag="VVO74_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694931.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(1201..2451)
                     /gene="ilvA"
                     /locus_tag="VVO74_000889"
     CDS             complement(1201..2451)
                     /gene="ilvA"
                     /locus_tag="VVO74_000889"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU5694932.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(2501..2857)
                     /locus_tag="VVO74_000890"
     CDS             complement(2501..2857)
                     /locus_tag="VVO74_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU5694933.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(3095..3331)
                     /locus_tag="VVO74_000891"
     CDS             complement(3095..3331)
                     /locus_tag="VVO74_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694934.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(3438..4460)
                     /gene="ilvC"
                     /locus_tag="VVO74_000892"
     CDS             complement(3438..4460)
                     /gene="ilvC"
                     /locus_tag="VVO74_000892"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU5694935.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGSRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(4526..5002)
                     /gene="ilvN"
                     /locus_tag="VVO74_000893"
     CDS             complement(4526..5002)
                     /gene="ilvN"
                     /locus_tag="VVO74_000893"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU5694936.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(4995..6695)
                     /locus_tag="VVO74_000894"
     CDS             complement(4995..6695)
                     /locus_tag="VVO74_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU5694937.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(6896..8563)
                     /locus_tag="VVO74_000895"
     CDS             complement(6896..8563)
                     /locus_tag="VVO74_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU5694938.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(8566..8931)
                     /locus_tag="VVO74_000896"
     CDS             complement(8566..8931)
                     /locus_tag="VVO74_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU5694939.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(9088..9276)
                     /locus_tag="VVO74_000897"
     CDS             complement(9088..9276)
                     /locus_tag="VVO74_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU5694940.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(9392..9568)
                     /locus_tag="VVO74_000898"
     CDS             complement(9392..9568)
                     /locus_tag="VVO74_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEU5694941.1"
                     /translation="MDLDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     NGMWRAENVTQDLI"
     gene            complement(9679..9877)
                     /locus_tag="VVO74_000899"
                     /pseudo
     CDS             complement(9679..9877)
                     /locus_tag="VVO74_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
     gene            complement(10305..11849)
                     /locus_tag="VVO74_000900"
     CDS             complement(10305..11849)
                     /locus_tag="VVO74_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU5694942.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNKRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            12062..12364
                     /gene="gatC"
                     /locus_tag="VVO74_000901"
     CDS             12062..12364
                     /gene="gatC"
                     /locus_tag="VVO74_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU5694943.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            12364..13830
                     /gene="gatA"
                     /locus_tag="VVO74_000902"
     CDS             12364..13830
                     /gene="gatA"
                     /locus_tag="VVO74_000902"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU5694944.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQTTLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLSAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            13830..15272
                     /gene="gatB"
                     /locus_tag="VVO74_000903"
     CDS             13830..15272
                     /gene="gatB"
                     /locus_tag="VVO74_000903"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU5694945.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNTEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            15401..15961
                     /gene="efp"
                     /locus_tag="VVO74_000904"
     CDS             15401..15961
                     /gene="efp"
                     /locus_tag="VVO74_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU5694946.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            15983..16372
                     /locus_tag="VVO74_000905"
     CDS             15983..16372
                     /locus_tag="VVO74_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU5694947.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            16365..16787
                     /gene="nusB"
                     /locus_tag="VVO74_000906"
     CDS             16365..16787
                     /gene="nusB"
                     /locus_tag="VVO74_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU5694948.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQMVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(16837..17073)
                     /locus_tag="VVO74_000907"
     CDS             complement(16837..17073)
                     /locus_tag="VVO74_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5694949.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(17086..17559)
                     /locus_tag="VVO74_000908"
     CDS             complement(17086..17559)
                     /locus_tag="VVO74_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694950.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(17577..17762)
                     /gene="briC"
                     /locus_tag="VVO74_000909"
     CDS             complement(17577..17762)
                     /gene="briC"
                     /locus_tag="VVO74_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEU5694951.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(17921..18688)
                     /locus_tag="VVO74_000910"
     CDS             complement(17921..18688)
                     /locus_tag="VVO74_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU5694952.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(18685..19551)
                     /locus_tag="VVO74_000911"
     CDS             complement(18685..19551)
                     /locus_tag="VVO74_000911"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU5694953.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(19588..20955)
                     /gene="accC"
                     /locus_tag="VVO74_000912"
     CDS             complement(19588..20955)
                     /gene="accC"
                     /locus_tag="VVO74_000912"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU5694954.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVKKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(20967..21389)
                     /gene="fabZ"
                     /locus_tag="VVO74_000913"
     CDS             complement(20967..21389)
                     /gene="fabZ"
                     /locus_tag="VVO74_000913"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU5694955.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(21386..21871)
                     /locus_tag="VVO74_000914"
     CDS             complement(21386..21871)
                     /locus_tag="VVO74_000914"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU5694956.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(21874..23109)
                     /gene="fabF"
                     /locus_tag="VVO74_000915"
     CDS             complement(21874..23109)
                     /gene="fabF"
                     /locus_tag="VVO74_000915"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU5694957.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(23131..23862)
                     /gene="fabG"
                     /locus_tag="VVO74_000916"
     CDS             complement(23131..23862)
                     /gene="fabG"
                     /locus_tag="VVO74_000916"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU5694958.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(23896..24816)
                     /gene="fabD"
                     /locus_tag="VVO74_000917"
     CDS             complement(23896..24816)
                     /gene="fabD"
                     /locus_tag="VVO74_000917"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU5694959.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(24809..25783)
                     /gene="fabK"
                     /locus_tag="VVO74_000918"
     CDS             complement(24809..25783)
                     /gene="fabK"
                     /locus_tag="VVO74_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU5694960.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(25903..26127)
                     /locus_tag="VVO74_000919"
     CDS             complement(25903..26127)
                     /locus_tag="VVO74_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU5694961.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(26187..27161)
                     /locus_tag="VVO74_000920"
     CDS             complement(26187..27161)
                     /locus_tag="VVO74_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU5694962.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(27161..27595)
                     /locus_tag="VVO74_000921"
     CDS             complement(27161..27595)
                     /locus_tag="VVO74_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU5694963.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(27689..28474)
                     /locus_tag="VVO74_000922"
     CDS             complement(27689..28474)
                     /locus_tag="VVO74_000922"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU5694964.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            28844..30208
                     /locus_tag="VVO74_000923"
     CDS             28844..30208
                     /locus_tag="VVO74_000923"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU5694965.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREIGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYYAFFGE
                     SKED"
     gene            30211..30582
                     /locus_tag="VVO74_000924"
     CDS             30211..30582
                     /locus_tag="VVO74_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU5694966.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKVSRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            30796..32070
                     /gene="serS"
                     /locus_tag="VVO74_000925"
     CDS             30796..32070
                     /gene="serS"
                     /locus_tag="VVO74_000925"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU5694967.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(32095..32994)
                     /locus_tag="VVO74_000926"
     CDS             complement(32095..32994)
                     /locus_tag="VVO74_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU5694968.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(33104..33652)
                     /locus_tag="VVO74_000927"
     CDS             complement(33104..33652)
                     /locus_tag="VVO74_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU5694969.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(33870..35186)
                     /locus_tag="VVO74_000928"
     CDS             complement(33870..35186)
                     /locus_tag="VVO74_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU5694970.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAKTNEPVEQGLISMTGTFIDTLIICTLTDLTILVTGVWSGDLNGVALTQS
                     AFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLMVL
                     LGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFNK"
     regulatory      complement(35277..35365)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(35529..37865)
                     /locus_tag="VVO74_000929"
     CDS             complement(35529..37865)
                     /locus_tag="VVO74_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU5694971.1"
                     /translation="MNKKILETLELDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLTSREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKVKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(37969..38517)
                     /locus_tag="VVO74_000930"
     CDS             complement(37969..38517)
                     /locus_tag="VVO74_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU5694972.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(38514..38816)
                     /gene="zapA"
                     /locus_tag="VVO74_000931"
     CDS             complement(38514..38816)
                     /gene="zapA"
                     /locus_tag="VVO74_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU5694973.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            38903..39784
                     /locus_tag="VVO74_000932"
     CDS             38903..39784
                     /locus_tag="VVO74_000932"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU5694974.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKKRLER"
     gene            39788..40402
                     /gene="lepB"
                     /locus_tag="VVO74_000933"
     CDS             39788..40402
                     /gene="lepB"
                     /locus_tag="VVO74_000933"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU5694975.1"
                     /translation="MNSLKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKLLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            40482..40604
                     /locus_tag="VVO74_000934"
     CDS             40482..40604
                     /locus_tag="VVO74_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chlorohydrolase"
                     /protein_id="HEU5694976.1"
                     /translation="MKIKEQTRKLAVGCLKQWFEVVDRTDEVSSKYCFEVADGS"
     gene            40681..43047
                     /locus_tag="VVO74_000935"
     CDS             40681..43047
                     /locus_tag="VVO74_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU5694977.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGEQKRQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLTNQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGVALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(43095..44378)
                     /locus_tag="VVO74_000936"
     CDS             complement(43095..44378)
                     /locus_tag="VVO74_000936"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU5694978.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT        13006 a        10181 c         8418 g        12972 t
ORIGIN      
        1 aaataaaaag aaaaggctgc atcaaccgtg cagtcttttt gctgtcctca aaatgaaaag
       61 gcagattctc tatctctact acttgaaggt caagaatcca ccgttatcca aagattaatc
      121 ttcaaatttt tcatgatttt tttcatagaa atcaattaag cctagggctg tttcaaatga
      181 aatatttttt acttttgcac gaccctgcgc cagagcaatg atagacattt cacgcgcatt
      241 cgtttcttta gagatacggt agcctgtgat tttcttatca cgaacccagc caacaactga
      301 ttctactttt tcaaagtttg acttagccat gtttttctcc tattttcttc tttataatat
      361 ttaattgtat acgtttttac tacttttgtc aataaaaaaa acatatattc aacgaaaata
      421 attagttcag aattttctta cttccttttt aaatccgata atatataggt tttgctagcc
      481 tctacaccat aaatatttgc taataaaaat actgtattat taccctctta aggtgcgaaa
      541 ttattcaagt tcttaaaaaa tgcttctcta tttccgtaag atagcttatt tcttcgattt
      601 aagaactgaa gatgatagtt ctaaccttta gaaatccaag ccttctctag ctcaaaaact
      661 cctatctttc ttcctcaata aatcatctga gagataggta ttccttatat ccttcaaatt
      721 catcactcct ttggatattg aggtgctagc ctagaagcag acacccgatt atctaaacca
      781 tccttaatag agatgacaag acagataagc tcagttaatt acttatatat ctttttaata
      841 tggtatattt gtcaacaaaa agaaatcaaa tcatacctta tactcaatga aaatcaaaga
      901 gcaaactagg aagctagccg caaattgctc aaaacactgt tttgaggttt cagatagagc
      961 taacgtggtt tgaagagatt ttcgaagagt attaaagaca gtatgactat gcttgtcaat
     1021 agataggaaa tcaaaatgaa ggatggaaat ctgagccaaa catcataagt gctataatga
     1081 acagaagtaa gaattgcacg ataagttttc taaaaccata ggaatcgtcc cctttcttca
     1141 tcttcattat agcacatata catcagttgt acaaataata tgatattttt ttattagtcc
     1201 tcagacaagc atattataaa gcgtttcatt accatttaag ttaatataag ctggatcaaa
     1261 accttccatt ctacggatca aacctgcata atcatgctta tctgccaaag cgatcccaat
     1321 caatactggg cctgttccct tgctagctcg tttgatatac tcaaaacgtg tgatatcatc
     1381 atttggcccc aggatatcat ttacaaactc acgcaaagct cctggacgct gtgggaaatt
     1441 gaccacaaag taatgtttga taccatcata aatcaaggca cgctcttcca tttctggcat
     1501 acggttgata tcattatttc ctccagaaat gatacaacaa atggttttcc ccttaatata
     1561 ttcagctaaa acctctaaag aggcgatact agccgctcca gcaggttctg cgactatccc
     1621 ttgcttagag taaaggtcaa tcaaggtttc agaaatcaat ccctcatcga cacctaccaa
     1681 agtttgaata tgttgacgag ttgcttcata ggtcaactga cctacctttt gcacagcaat
     1741 cccatccgca aatttatcaa tttccttgag tttgactgga cctccagcct caaaggcagc
     1801 tttcatggaa cgcgctccat tcgcctctac tccgataacc tcaatctctg gacttgtttc
     1861 cttgatatag gtagaaaccc cggcaatgag accgccacca ccaacaggaa ccaagacagc
     1921 atcaaaatca atcgattctt ttcgagcttc ttctaaaatc tcataagcaa ctgttccttg
     1981 acctgcttga acatgagcat catcaaaagg atcaataaag gtacgatttt cagagactgt
     2041 aaattcttga gctgctttgg ctgaggcatc aaaggtatct ccaactagtt taatagttac
     2101 aaaatcccca ccaaaaaagc gaacctgacc aatcttttgt tgtggcgtag taataggcat
     2161 aaagatagta gcaggaattt tcatttcatt acaagtatag gctactccct gcgcatgatt
     2221 tcccgcagaa gcgcagacta ccccacgttc acgttcttcc ttgctgagct gggaaatggc
     2281 ataataggca ccacgaattt taaaggagcg aacacgctgg gcattttctt ttttcaaata
     2341 aatcttagca ccatacttct ccgataaata atgatcgtaa tccagtggag tattcacaac
     2401 cacaccgttc aagaccttgt gagccttgat tatatctttt gaacttaaca tataaaacct
     2461 ctttttctat aaaaaacagt cactaatgac tgttttttag ttattcatct ccgaaaactt
     2521 cagtaacact ttcatggtat ttatgagcca tacgaatcga aaactcttta ggaagttcat
     2581 aacgatttgt ggaaatccaa tcatataacc attctaccaa actttcttca ctatcattac
     2641 gatggaagat aaaatagttt aaaatttctt tatattctac atcattcaaa tccaacgtgt
     2701 ctacaaattg actacgagga acaaaattag aatctaattt tcttagttga tctgtcaatt
     2761 ctcccaattg taaatccaac tgaaaaaata gtttttgcag ttgcctatca gtttcatcac
     2821 atcctgtctt gatagaaaac aaattggtaa tattcatatg atttcaaccc ctaaataagt
     2881 acatctaata tcccacgaat agctgaagct aaagttttcg cagtccagtc atttaaaccc
     2941 gattctttca atccagatgc aataatttgc tctatttgat ataaaccgcc atctatcgtc
     3001 tcatttattc tgcgaagagg accttcaata taggataaag cttctccgaa tctaacagct
     3061 gatttaggtc ctaatgattt accaactata tttgttaatg ttttttattt ctcaaaatcc
     3121 atttcgctat ataacgagca gatttagtcg caccagctct ctcaaacgga gaatgaattt
     3181 caagaccttc ttctctagct atttgtgcca atttgaagaa ttgttcaaag gtcatatgca
     3241 acctaccatc ttcaaaatta gcatcatcat aaatgttaat tacagcattt tcatcatacg
     3301 accaatctgc tttattttgg tctgctagca ctattaccga cggtgtaatt acattataca
     3361 actagaacca ataataacga tgcaattttt ctcataatct ttttcataaa atcatctcca
     3421 gcgctatata tttctaatta gttatagatt ttgaatgcat catcgtcgtt tttaccaaca
     3481 aatggcattg ctttacgcaa ttctgcacca actttttcaa tttcaaggtt agctgcttgt
     3541 tcacggtaag cagtcaattt tggacgtcca gctttatagt catttacaaa gtcatttgca
     3601 aatttaccat tttggatgtc tgccaagaca gccttcatat tttctttaac ttgttcagtg
     3661 attacacgtg aacctgatac atagtcaccg tattcagcag tgtttgaaat agattgacgc
     3721 attttcttga atccaccttc gtagatcaag tcaacgatca atttcatttc gtgaagaact
     3781 tcaaagtaag ccaattctgg agcgtaacct gcttctgtca agacttcgaa acctgcttcg
     3841 ataagggcag tcaaaccacc acaaagtaca gcttgttcac caaacaaatc ttcttcagtt
     3901 tcttctttgt aagttgtttc aagaagacct acacgagccg ctccaacacc tttacaccag
     3961 tccatagcaa tgtttttagc atttcctgtt gcatcttggt atactgcata aagagctgga
     4021 acaccaaatc cttcttcgta agtacgacgt accaagtgtc ccggtccttt aggagcacac
     4081 atgaagacat ctacatccgc aggaactttg ataaattcaa agtggatgtt gaaaccatgg
     4141 gcaaatccaa ctgcgtttcc agcttccaag tttggagcga tttctgcttc gtacaattct
     4201 tgttgaattt cgtctggcgc caagatcatg ataacatcag ccaacttagt agcttctact
     4261 actgtgtaag tatcaaatcc atcttctttt gctttatcaa aagatttacc tggacgtaca
     4321 ccgataataa cgtcacgacc tgaatcacgc aagttttgag catgcgcatg tccttgtgaa
     4381 ccataaccga taacggcgat ttttttaccg tcaagtgctg ctactttaac atctttttca
     4441 tattccattt gaactgtcat agcttttctc tcttttctat tatttattgc cttttaggct
     4501 ggtttaataa atttaagttg gatttttaat cgcgggtaaa tccagttgca cccgttcgag
     4561 caatattgcg aataccgtat gggcgaatga ctcgcaatag ggcttcgctc ttttctgcat
     4621 ttcccgtcat ctgaatggta atcgagcttg gcgctacgtc taccactgtt gcacggaaag
     4681 gttgaataat cgctaaaatc tcagctctct tctcagctgg cgctgacatc ttaaccaaaa
     4741 tcacctcgcg ctccaaatga ggcttgtctg taatatctcg aatgcgaatc acatcaatct
     4801 gacgattgag ctgtttgatg atttgctcca cttcatcatg agaagcaaca tcaataataa
     4861 tagtgatacg cgatacattc ggatcttctg ttgctccaac agagatgctt tcaatattaa
     4921 cctgacgacg agataggaca cctgtaaagc gattgaggac tcctgaacga ttttgtagtt
     4981 ttgctgttaa cattctacgc atggaactgc acccccaaca tctcatgatt actcttacca
     5041 gccggtacca ttggtaacac ctgttcctta cgagaaatat ctacctcaat tagcatagga
     5101 acatcctcag tgatgacttc aaggtcttga gccaaggtct caggattgtc aaacttatag
     5161 tttttaatac cataagcctg cgccatcaat tggaaatcag gaagggtatc aaagaccgac
     5221 tctgatgttc tgccttcata gaaggattcc tgccactggc gaaccattcc aagtgaatga
     5281 ttgttcagca taaccacctt gattggcacc ttgtaaatat tcaaaatagc caactcctgg
     5341 ttggtcattt ggaaaccacc atccccaaca aacaagacta cttccttatc tgggttagca
     5401 attttagcac cgattgctgc tggaattcca aagcccattg ttcccaaacc acctgaagtc
     5461 actaactgac gctcattttg gtagggataa tactgagctg tccacatttg gtgttgacca
     5521 acgtctgtta ccacaatggc atctccattc gtcaattcac caattcgttc aataactgct
     5581 tgcggttgaa ccacacgctc tttcttgtca taagaacgaa cacgattctt gtctttagtg
     5641 actttctcaa tccacttttc agtattgttg tgaactgttg gttctgctag caacatttgc
     5701 aaggccttct tagcatctcc aactacagga atgtctgcac tgataatctt gccaatctca
     5761 gctgggtcaa tatcaatgtg ggcaacctta gcattcttag cgaaagtctt aggattcccc
     5821 gtcaaacggt catcgaaacg agaaccaata ctaatcataa agtccgcttc cgtcatggca
     5881 atatttgctg cgaatgaccc gtgcatgcct cccattccaa gaaagagtgg gtgactcgtt
     5941 gcaatcgttc cttgtcccaa aagactggtt accactggaa tttgatagcg ttctgcaaat
     6001 tcatttagtt ccgtagcagc ctcagcataa ctaattccac caccagctaa caagactggc
     6061 tttttagcct tggacaattg cttcaagatt ttcttgattt gcatatcatt cggctcaaga
     6121 gtcggctgat aacttggtaa attcacttct ggtgaataaa tgaagtctgt ttctaaagca
     6181 gatatgtctt ttggtaggtc aattacaact ggccctggac ggcctgtagt tgcgatatgg
     6241 acagcttccg taatgatacg cggaatatca gctgtctcac gaacttggta attgtactta
     6301 gtgattggca tggtaattcc tacgatgtct gcctcctgaa aggcatcctt cccaatccct
     6361 gctcgcgcca cctgacctgt aaagaccaaa aggggaacgc tatcgctcat agcatccgca
     6421 atccctgtaa tggcatttgt tgctcctggt ccactagtga cgacggcaac acccaacttt
     6481 ccagttgatt tggcataacc ttcagcttca tgcaaacaac cttgctcatg gcgccctaga
     6541 atgtggcgaa tgcctttaaa attatatatc gcatcataaa aaggcaaaac cgcaccacca
     6601 ggataaccaa agatggtatc aactcctaaa tcacgaagtg tttccaaaac taggtccgac
     6661 cccgtcttag gagattctaa actgattttc tccattgttc ccctttcttt cctcttaaaa
     6721 ataacttgtt actatcatac cattttttca aaatttttca agataaaaga agaaattttc
     6781 tgaattttct attttaacgt ttatttatga atgttatttt tgtttttatt aaaaagatac
     6841 cgatttcatt tactaaaaaa gaaaaaagaa ctgatttctc agtccttcat taatcttatt
     6901 ccacactaaa taggtatggg taaacaggtt gttgaccttg gtgaatctcg acttcaacgt
     6961 cttcgaattc ttctacgatt tcttgagcga tttcattggc aagttcttcg cttccgtctt
     7021 caccgacata gaaggttacg atttcactat cttcatccaa catatgtttc aaggtttcag
     7081 tcaatgtttg gtgcatatca gggtttgaca caagaatttt tccatccacc atacctagat
     7141 tatcgttttc atggatttct aagccatcga tcgttgtatc acgcacggct gttgtgacgc
     7201 ttccgctaac gacatcgcta agagcagctg tcatacgctc ttggttttct tcaatggact
     7261 tgcttggatc aaaggcaaga agacttgtca taccttgagg aagagtgcga gcctctacca
     7321 ctactgctgg ttgctccaaa acttctgccg cagattgagc tgccatgaag atgttcttgt
     7381 tgtttggcaa gaagatgatg ttacgggcat tgacctgttc aacagccttg ataaagtctt
     7441 ctgttgaagg gttcatggtt tgaccgcctt cgataacata atccacgcct tgagaacaga
     7501 agatatctgc tagaccttta ccagccacca cagcaatcaa agcatactct ttttcttcag
     7561 ccgacttgat aacttgagta gcttctttct caacctgtgc ttcgtgttgg ttacgcatat
     7621 tgtcaacttt taccttgacc aagctaccat atttgagacc ttcttgcata acaagtcctg
     7681 gatcttctgt atgaacatgg actttgacaa tttcatcatc gttaacaacg aggagagaat
     7741 ccccaagctc atccaagtag ttacggaatt catcgtagtc aaaatcttta gcataggttg
     7801 gaccttgctt aagagctacc atgatttcag tacagtaacc aaacgtgatg tcctcagtcg
     7861 ctacgtgacc agctacagac ttatgatgct ctacattgat catctcactc atgttggcag
     7921 gagtcgctac aaagtcctca gatgcaatat attcgccagt aagggctgaa aggaaacctt
     7981 cgtagatgaa gaccaatcct tgaccacctg agtccacaac gccaacttct ttcaatactg
     8041 gaagcatgtc tggtgtttta gctagagctg ttttagcacc ttccaaggct gcgcgcatga
     8101 cttcaacagc gtcatctgtt tgctcagctt ttttcttagc accgatagca gctccacgag
     8161 aaactgttaa aatcgttcct tcaacaggtt tcatcactgc cttataggca acttccacac
     8221 ctgattggaa ggccagagcc aagtcttgac ctgttaactc gtctttatcc ttgatagctt
     8281 gggaaaatcc acggaaaagc tgagacgtaa tcactcctga gttcccacgc gcacccatca
     8341 aaagcccttt ggcaagaatg ctcgctactt ctccaactgt agaagctggc ttgtctgcaa
     8401 cttctttagc accattttca atggtcattc ccatatttgt cccagtatct ccatctggaa
     8461 ctggaaagac gtttaatgaa ttgacatatt cagcttgctt attcaagcga gttgatgcag
     8521 cctgcaccat ttcttgaaat aagctagtag taatttttga cacggttatt ctcctacaac
     8581 tttgatattt tgaatgtaga catttacagt ctgagcagta attccaagct ggttttccaa
     8641 gctaaaggca acacgctctt gaatgttttt tgacacttca ctaatctttg ttccgtagct
     8701 taacacggta tatacatcaa ctgcaatact gccatcttcg gctgccttta cgacgacacc
     8761 tttagaataa ttttccttac ctagcagggc ttggaaatta tctttgaggg catttttact
     8821 agccataccg accacaccaa aaatctcagt tgctgctcca cctacgacgg ttgcaatcac
     8881 ttcatctgtt agttcgattt gaccatcttt tgtattaatt tttacagtca tcctttttac
     8941 ctcaactagt tgatactcta ttttatcata tttcagccca agtgtaaaag cagaatgatg
     9001 tatcagcgga tatttactct atttttcaaa cgatgttata cccacaataa aagaaaaaag
     9061 accctaaggt ctcctttgct tttattatta aacgcgttca actttacctg atttcaaagc
     9121 acgagctgaa gcccaaactt ttttaggttt accatcgata agaacagtaa ctttttgaag
     9181 gtttggtttt acggcacgtt ttgtttggtt catcgcgtgt gaacggttgt ttcctgatac
     9241 agtcttacga cctgtaaagt aacatacttt agccattgtg ttttcctcct attagatcta
     9301 atatagcgga tgtgctagca ccacataccg tactatgtta tcacactttc ttgttttttg
     9361 caagggaatt ggaagatttt ttatttgtgt cttaaatcag gtcttgcgtg acattttctg
     9421 ctctccacat gccattgttg attaacagaa caccagaatt aaaattatgt gtataaaaat
     9481 catctctaac tgcagctaag ggtatagccg tcaagtccaa atcccacagc tcatctatcg
     9541 attttcttac aacaatatct aaatccaaat acagtacacg agactcgctt acatactttg
     9601 gaataaaata cctaaaaaag ccgcatatga aagtccctca aaggggagac gataaccttt
     9661 cagaatacta ctgtcaatct aaacattcac aatctcacta ttcaaagtct ctagtctttt
     9721 ttccatcaat tggaaccatt ctcgcggaag gtcatcatta aaaacataaa acttaagatt
     9781 ataatagatg aacacaaaga gattttattg ttgtttcaac tttatccata taagcattat
     9841 ctgcacctaa gacaatcgct tttttctctt ctttcactct ttatctcatt tctttttatt
     9901 cccatcatat gtttctacgt aaccattatt ttcgcccatt cgttcgtaaa accataccag
     9961 tggagatttt agatgaagtc ccattacggt ttacaatttt tacattacga cacggagttt
    10021 tacaaatcga tttcatttgc caaacgtagt tagtaaggca gttagctagg ctacctactt
    10081 tctgctacga cggaaaaatc cacaaatcaa taccattcgt ggatttttcc tagtgaagcg
    10141 tttaggtaag ccgccatagc ggttaccgat tattagatta cgacacggag tttggcaaat
    10201 cgattctatt tgccaaacgt agttagtgag gcagttagct agttcgccaa atagcgacta
    10261 gcgtccaaca atttggaact ttagttccaa ttgttggtac tgagtcacat cttctcctct
    10321 aactctacgt ctggatactt gtccgcaaac cagcggaggg caaagtcatt ttcaaagaga
    10381 aagactggtt ggtcaaaacg gtctttggct aagatattgc gacttgatga catccgttca
    10441 tccaaatcct caggcttgat ccaacgaacg gtctttttac ccattgggct catgaccact
    10501 tccgcattat attctccttc catacggtgc ttaaagactt caaactggag ttgacctaca
    10561 gcgcctagca tgtactcacc tgtttggtaa ttcttataaa gctgaacggc tccttcttgc
    10621 actagttgct caatcccctt gtggaaggat ttttgcttca tgacattctt agcagaaact
    10681 ttcatgaaaa tttcaggagt aaaggttggc aatggttcaa attcaaattt gtttttccca
    10741 actgtcaagg tatccccaac ctgataagtg cctgtatcgt aaaccccgat aatatcacct
    10801 gccacggcat tggtcacatt ctcacgactt tccgccataa actgggtaac attagacagt
    10861 ttagccccct taccagtacg agggagatta acactcatgc cgcgctcaaa ttcgccagat
    10921 acgatacgga caaaggcaat acggtcacgg tgacgagggt ccatgttggc ttggatttta
    10981 aagacaaagc ctgagaaatc cttgtcataa ggatccacaa tttcaccgtc tgttttcttg
    11041 tgaccatgtg gttctggagc aaacttgagg aaggtttcaa ggaaggtctg cacaccaaag
    11101 tttgtcaggg ctgaaccgaa aaagacaggc gtcaattctc cagccagaat agcttcctct
    11161 gaaaactcat tcccggcttc atttaaaagc tcaatatcat ccttgacttg ctcgtagaaa
    11221 ggattgctac caaaaagttt gtccccatct tctagactag caaaacgctc atccccttta
    11281 taaagctcta aacgtttgtt atagaggtca tacaagccct caaaggcttt ccccatcccg
    11341 ataggccagt tcatagggta gctagcaatg cccaagattt cttccaattc ttgtaagaga
    11401 tccaaaggct cacgaccgtc acggtccagc ttgttcataa aggtaaagac tggaatgcca
    11461 cgatgtttca caacctcaaa caatttcttg gtttgagcct cgatcccctt ggcagagtcc
    11521 acgaccatga ccgcagcatc caccgccatc aaggtacgat aggtatcttc tgagaagtcc
    11581 tcgtgccctg gcgtgtctaa gatattcacg cgcttgccgt cgtagtcaaa ttgcataaca
    11641 gatgaagtaa cagaaatccc acgttgcttc tcgatatcca tccaatcaga tttagcaaaa
    11701 gtccctgttt tcttcccttt taccgtacca gcctcacgaa tttcaccccc aaagtagagt
    11761 aactgctcag tgatggttgt tttccccgcg tccgggtggg agataatggc aaaggtacga
    11821 cgtttcttaa tttcttcttg aatattcata agttctcttt ctttgattct ctatttttct
    11881 tgtttcaata gctgagaatg atttttacat tggattttac cattcctttc aacactccat
    11941 tatatcggat tttagcattt ttttcaattt ctatttcttt tcacttcccc ctcccttatt
    12001 tataggaaaa tatggtaaaa tagaacagac taaaaatcat catttcacga aaggatgcaa
    12061 gatgaaaatt acgcaagaag aggtaacaca cgttgccaat ctttcaaaat taagattctc
    12121 tgaaaaagaa actgctgcct ttgcgaccac cttgtctaag attgttgaca tggttgaatt
    12181 gctgggcgaa gttgacacaa ctggtgtcgc acctactacg actatggctg accgcaagac
    12241 tgtactccgc cctgatgtgg ccgaagaagg aacagaccgt gatcgcttgt ttaaaaacgt
    12301 acctgaaaaa gacaactact atatcaaggt gccagctatc ctagacgatg gaggagatgc
    12361 ctaatgactt ttaacaataa aactattgaa gagttgcaca atctccttgt ctctaaggaa
    12421 atttctgcaa cagaattgac ccaaacaaca cttgaaaata tcaagtctcg tgaggaagct
    12481 ctcaattcat ttgtcaccat cgctgaggag caagctcttg ttcaagctaa agccattgat
    12541 gaagctggaa ttgatgctga caatgtcctt tcaggaattc cacttgctgt taaggataac
    12601 atctctacag acggtattct cacaactgct gcctcaaaaa tgctctacaa ctatgagcca
    12661 atctttgatg cgacagctgt tgccaatgca aaaaccaagg gcatgattgt cgttggaaag
    12721 accaacatgg acgaatttgc tatgggtggt tcaggtgaaa cttcacacta cggagcaact
    12781 aaaaacgctt gggaccacag caaggttcct ggtgggtcat caagtggttc tgccgcagct
    12841 gtagcctcag gacaagttcg cttgtcactt ggttctgata ctggtggttc catccgccaa
    12901 cctgctgcct tcaacggaat cgttggtctc aaaccaacct acggaacagt ttcacgtttc
    12961 ggtctcattg cctttggtag ctcattagac cagattggac cttttgctcc tactgttaag
    13021 gaaaatgccc tcttgctcag cgctattgcc agcgaagatg ctaaagactc tacttctgct
    13081 cctgttcgca tcgccgactt tacttcaaaa atcggccaag acatcaaggg tatgaaaatc
    13141 gctttgccta aggaatacct cggtgaagga attgatccag aagttaagga aacaatctta
    13201 aacgcggcca aacactttga aaaattgggt gctattgtcg aagaagtcag ccttcctcac
    13261 tctaaatacg gagttgccgt atactacatc atcgcttcat cagaagcttc atcaaacttg
    13321 caacgctttg acggtatccg ttacggctat cgcgcagaag atgcaaccaa ccttgatgaa
    13381 atctatgtaa acagccgaag ccaaggtttt ggtgaagaag tgaagcgccg tatcatgctg
    13441 ggtactttca gtctttcatc aggttactac gatgcctact acaagaaggc tggacaggtc
    13501 cgtacactta tcattcaaga tttcgaaaaa gtcttcgcgg attacgattt gattttgggt
    13561 ccaactgctc caagtgttgc ctatgacttg gattctctca accatgaccc agttgccatg
    13621 tacttagccg acctattgac catacctgta aacttggcag gactgcctgg aatttcgatt
    13681 cctgctggat tctctcaagg tctacctgtc ggactccaat tgattggtcc caagtactct
    13741 gaggaaacca tttaccaagc tgctgctgct tttgaagcaa caacagacta ccacaaacaa
    13801 caacccgtga tttttggagg tgacaactaa tgaactttga aacagtcatt ggacttgaag
    13861 tccacgtaga gctcaacacc aattcaaaaa tcttctcacc tacttctgcc cacttcggaa
    13921 atgatcaaaa tgccaacact aacgtgattg actggtcttt cccaggagtt ctgccagttc
    13981 tcaataaagg ggttgtcgat gccggaatca aggctgctct tgccctcaac atggacatcc
    14041 acaaaaagat gcactttgac cgcaagaact acttctatcc tgataacccc aaagcctacc
    14101 aaatttctca atttgatgaa ccaatcggat ataatggctg gattgaagtc gaactagaag
    14161 acggtacgac caagaaaatc ggtatcgaac gtgcccacct agaggaagac gctggtaaaa
    14221 acacccatgg tacagatggc tactcttatg ttgacctcaa ccgccaaggg gttcccttga
    14281 ttgagattgt atctgaggca gatatgcgtt ctcctgaaga agcctatgct tatctgacag
    14341 ccctcaagga agttatccag tacgctggca tttctgacgt taagatggag gaaggttcga
    14401 tgcgtgtgga tgccaacatc tcccttcgtc cttatggtca agagaaattc ggtaccaaga
    14461 ctgaattgaa gaacctcaac tccttctcaa acgttcgtaa aggtcttgaa tacgaagtcc
    14521 aacgccaggc tgaaattctt cgctcaggtg gtcaaatccg ccaagaaaca cgccgttacg
    14581 atgaagcgaa taaagcaacc atcctcatgc gtgtcaagga aggggctgct gactaccgct
    14641 acttcccaga accagaccta cccctctttg aaatttctga cgagtggatt gaggaaatgc
    14701 ggactgagtt gccagagttt ccaaaagaac gtcgtgcgcg ttatgtatct gaccttggtt
    14761 tatcagacta cgatgctagt cagttgactg ctaataaagt cacttctgac ttctttgaaa
    14821 aagctgttgc cctaggtggt gatgccaaac aagtctctaa ctggctccaa ggggaagtcg
    14881 ctcagttctt gaatactgaa ggtaaaacac tggaacaaat cgaattgaca ccagaaaact
    14941 tggttgaaat gattgccatc atcgaagacg gtactatttc atctaagatt gccaagaaag
    15001 tctttgtcca tctagctaaa aatggcggtg gcgcgcgtga atacgtggaa aaagcaggta
    15061 tggttcaaat ttcagatcca gctatcttga tcccaatcat ccaccaagtc tttgccgata
    15121 acgaagctgc tgttgccgac ttcaagtcag gcaaacgtaa cgccgacaag gcctttacag
    15181 gattccttat gaaggcaacc aaaggccaag ccaacccaca agttgccctt aaactacttg
    15241 cacaggaatt ggcgaagttg aaagaaaact agacagaaca aaaccagccc taaggttggt
    15301 tttttcttct ctcccaactc ccaataacta ttttggcttt atttccagag tattttatgg
    15361 taaaatgaag agtaataata tttattaaag aggtaaaaac atgattgaag caagtaaatt
    15421 aaaagctggt atgacctttg aaacagctga cggcaaattg attcgcgttt tggaagctag
    15481 tcaccacaaa ccaggtaaag gaaacacgat catgcgtatg aaattgcgtg atgtccgtac
    15541 tggttctaca tttgacacaa gctaccgtcc agaggaaaaa tttgaacaag ctattatcga
    15601 gactgtccca gctcaatact tgtacaaaat ggatgacaca gcatacttca tgaatacaga
    15661 aacttacgac caatacgaaa tccctgtagt caatgttgaa aacgaattgc tttacatcct
    15721 tgaaaactct gatgtgaaaa tccaattcta cggaactgaa gtgatcggtg tcaccgttcc
    15781 tactactgtt gagttgacag ttgctgaaac tcaaccatct atcaaaggtg ctactgttac
    15841 aggttctggt aaaccagcaa cgatggaaac tggacttgtc gtaaacgttc cagacttcat
    15901 cgaagcagga caaaaactcg ttatcaacac tgcagaagga acttacgttt ctcgtgccta
    15961 atctctagaa agaggtcatt ctatgggaat tgaagaacaa cttggcgaaa tcgttatcgc
    16021 cccacgtgta cttgaaaaaa tcattgctat cgctactgca aaggtagagg gtgttcactc
    16081 tttttcaaac agatcagtgt ctgataccct ttcaaaactt tcactcggcc gtggcattta
    16141 tcttaaaaac gtggacgaag aactcacagc agatatctat ctctaccttg agtacggagt
    16201 aaaagttcct aaggtagcgg ttgctatcca gaaagctgtc aaagatgccg tccgtaatat
    16261 ggctgatgta gaactcgctg ctatcaatat tcacgttgca ggtatcgtcc cagataaaac
    16321 accaaaacca gaattgaaag atctatttga cgaggacttc ctcaatgact agtccactat
    16381 tagaatctag acgccaactc cgtaaatgcg cttttcaagc tctcatgagc cttgagttcg
    16441 gtacggatgt cgaaactgct tgtcgtttcg cctatactca tgatcgtgaa gatacggatg
    16501 tacaacttcc agcctttttg atagacctcg tttctggtgt tcaagctaaa aaggaagaac
    16561 tagataagca aatcactcag catttaaaag caggttggac cattgaacgc ttaacgctcg
    16621 tggagagaaa cctccttcgc ttgggagtct ttgaaatcac ttcatttgac actcctcaga
    16681 tggttgctgt taatgaagct atcgagcttg caaaggactt ctccgatcaa aaatctgccc
    16741 gttttatcaa tggactgctc agccagtttg taacagaaga acaataaaaa gaaaaagtgt
    16801 ttgatagata tcaaacactt ttttctttgc ctcccactat ctaaaaaaat gataatagat
    16861 ataattgtaa acaaaaatcc agataggttt tgcatgattg agaaagttaa aaaaactatg
    16921 gcagagaatc gttaatctca gattgtcggt agaacgataa acaagggcaa aaaagaaacc
    16981 aatcagacta taatataata aactaattgg atctctgtga gatagtatca aatggctaat
    17041 cccaaagatg atagcagata ggataacatc caaatagtac ttggactagg gaaagaaggt
    17101 attcataaaa taccctctat caagagtctc ctcaaaaaca ggaccgatga ttacaggcag
    17161 gacaaaagat aagatagtcg ataaaaaggt tggttgtcca tttgaaaaaa gcacggtaaa
    17221 atactcatca tgaatattcc tatgattaat caaatgagca tagcgtgccc aaaaattacc
    17281 gagaatctga taaaccacat aagttgcaaa taagtagaag acaaatgacc agttccagct
    17341 ctttttctca aagataaaga gcatcttttt cttttttaac ctccaaatta atagaaggaa
    17401 acttcccact aatcccattg ttaaaataag agaatagaca tcagctccta accctaaaat
    17461 gatcgtcaca tacaatccaa ttgtttgtgg taaataggta gatagtaaaa taataagcaa
    17521 aaatattcca aattgtctta gtttttttgt gtttctcatc gtactttttt gaaagattac
    17581 cctgctcgga agccgtactt ccaagcatct atataagaat taagtgcccc ttgcctcata
    17641 tagggagcaa attctctata atataaccat ctactatatc catcttccca aacagcaaga
    17701 ccacctgaag tttgctccaa gtcctcagtt gaaagaactg taaatgtatt tgtacctgtc
    17761 attgcaagta ccttcttaaa atagattgtt gtaggttcac atttatagta tatttctttt
    17821 tttgtctatt ttatagccca tctcctcaac tggcaatttt tcgacctgaa ttacattttt
    17881 ccataaaaaa tgagaccttt ctagtctcat ttagtcattc ttagtatttt ctaaatcgtt
    17941 gatagcgttc ttccagcaac tcttctagcg gtttttgtga aagtctagcc agctccgttt
    18001 ggagttcttt tttgacactc ttaatcagtt ctttactaga aagtcctatt tcagaaatca
    18061 ccttatccac cacgtccatt tctaacagtt catgcgaagt gattttcatc agttctgctg
    18121 cttccatagc gcgagtaccg tccttccata aaatggaagc aaagccttct ggactgagaa
    18181 tggcatagat agaattttcc agcatccaga cacggtccgc gacagctaga gccagagccc
    18241 cgcctgaacc accttcaccg ataataatgg cgataatagg aactttcagg tcactcattt
    18301 ccatgagatt gcgagcgata gcttcccctt gaccacgttc ttccgctccg acaccaggat
    18361 aagcacctgc tgtattgata aaggtcacaa ctggacggcc aaatttctca gcctgtttca
    18421 tcaaccgcag tgcctttcgg tagccttctg gatgtggttg gccaaaattc cgtttgaggt
    18481 tgtcttgcaa actcttgcct ttttggatac caaccactgt tacagcttga tctccaagcc
    18541 aaccaatacc accaacaact gcaccatcat cacgaaaaga acggtcacca tgtaattgga
    18601 taaattcatc aaaaatgcct gtcgcaaagt ccaaggttgt caagcgactc tgctcacgcg
    18661 cttctctgac tatttttgca atattcatct aggactccct ccatgcaatc tgactaggct
    18721 agcaatcgta tctggtaagt ctcttctttt gacaatagca tccacaaagc catgttctaa
    18781 taggaattct gccttttgga aatcctcagg caagctttca cgaaccgtat tttcaatcac
    18841 acgacgccca gcaaaaccaa ccaagctctg tggttcagcc agaatgatat cgccttccat
    18901 agcgaaagaa gctgtcacac caccagtcgt tggatctgtc aaaatggtca ggtaaaagag
    18961 accagcattt gaatggcgtt taaccgccgc agagatctta gccatctgca tgagactcat
    19021 gattccttcc tgcatacggg ctccaccaga ggctgtgaat aggacaactg gcaatttttc
    19081 gacagtcgca tactcaaaca aacgagtgat tttttcacct acaaccgtac ccatagaagc
    19141 catgataaag ttagaatcca taatcccaag agccacagtc tgacctttaa taagagcagt
    19201 tcctgtcaca acggcttcat gcagacctgt tttttcacgc atagatgcca gtttcttttg
    19261 gtaaccaggg aaatgcaagg gatccttgct ttcaatccct gtaaacaatt ctttgaaggt
    19321 tcccatatca atcgtcaaag ccaagcgttc ttgggcagaa atacgaaagg tatagctaca
    19381 gtgcggacag atacgttcac ttcccagatc cttctgatag atggtatgct tacagcctgg
    19441 acactgggaa aataattcat ctggaacctc tggcttagct tgaggttttt ccctaaccga
    19501 acgattggga ttgattcgaa tatacttatc ttttttacta aatagagcca ttgattcccc
    19561 ttttcggttt aaactcttaa agtcatttta ttctttttct tgatatttag gtaagaaggt
    19621 ttccatcaag aaggaagtat cataatcccc agcaatgaca ttgcgatctg aaatgaggtc
    19681 aagctggaaa tctgcattgg tctgcactcc ttcaatctct aattcataga gggcacgttg
    19741 cattttcatc aaggcgtcaa aacgattttc gccgtgtact atgattttgg caatcatact
    19801 atcataataa ggcggaatgg tataacctgg ataaactgct gaatccacgc gcaagccaac
    19861 tccaccactt ggcagataga gattagtaat cttacctgga cttggagcaa agttaaaggc
    19921 tgggttttct gcattgatac gacactcgat ggcatgaccg cgtaggacaa tatcttcttg
    19981 cttaacagac aaaggctgac ctgccgcaat gcaaatctgt tccttaacga tatcaacacc
    20041 tgaaacaaac tctgttactg gatgttctac ctgaacacga gtattcatct ccatgaaata
    20101 gaaattgcta cttgcttcat caagaagaaa ttcaatggtt cctgcattct catagccaac
    20161 aaactctgcc gctcgaacag cagcagcacc tatttcatga cgcagcgttt ttccgattgc
    20221 aatcgaggga ctttcttcca aaaccttttg gttattcctt tgaagagaac aatcccgttc
    20281 acccaagtga atcacatgtc catgctcatc acctaggatt tgaacctcaa tgtgccgagc
    20341 tggatagata acccgttcta tgtacatggc accattgcca taattggcct tggcctcact
    20401 agaggcagtt tcaaaggcag aaacgaggtc atctggtttt ttaaccttac gaatcccttt
    20461 accacctcca cctgctgaag ccttgagcat aacaggatag ccaatttttt cagcaacaat
    20521 caaagcttct tcagagttat gcacttctcc atctgaacct ggtataacag gcacacctgc
    20581 tttaatcatc tgagcacgcg cattgatctt atcccccatc atatccataa catgaccaga
    20641 tggaccgata aacttgatac ctacttcttc acacatggtc gcaaatttgg aattttcact
    20701 gagaaatcca aaaccagggt gaatagcttc tgcctcagtc aagactgcag ctgatagaac
    20761 tgcattaata ttgagataag actctgttgc cttgccagga ccaatacaaa ctgcttcatc
    20821 tgccaaaagc gtatgaagag cttccttatc agcagttgaa taaaccgcta ccgtcgcaat
    20881 ccccaattca cgtgccgcac ggataatacg aaccgcaatt tcaccacgat tggcaattaa
    20941 aatttttcga aacatggaga acctccttag ttcccaattg caaaagtaag ggtaccactg
    21001 gctgcaagct tgccatccac ttcagccttt gcttcaacca cagctatggt gccacgacgt
    21061 tttacaaaag tcgctgtcat aaccaattgg tcgcctggta caacttgctt cttgaactta
    21121 accttgtcca taccagcgta aaagaccagt tttcctttat tttcaggttt tgataactcc
    21181 aacacaccgg cagtttgcgc caaggcttcc ataatcagaa cacctggcat aactgggtat
    21241 tgaggaaagt ggccgttaaa gaaaggttcg ttaatggtca catttttgat agcaacaatg
    21301 gtatcctcgc tcacttccaa gacacggtcc actagaagca taggataacg gtggggaaga
    21361 gcttctttga ttccttgaat atcgatcatt tgatacgtac caatccttta ccaaactcaa
    21421 ccatttcttc gttagagacg agaatttccg ttaccacacc atccttagga gctgggattt
    21481 cattcatgac tttcatggct tcgataatta ccaatgtttg accttttttg acactatcac
    21541 caactgtaac gaaggcaggt ttatctggtc cagcagccaa gtaaaccact ccaacaagtg
    21601 gactctctac aagatttccc tcagtagcca cacttgcttc agctggagct ggaacttctt
    21661 ctgctacagt ctctgctgga gcagatgtag gagctactgg actcggtgtt gctagaacgg
    21721 gtgctggagc gacttgagtt gcaacttcag gcacaggtct tgcttcattc ttgctaaact
    21781 gcaactcatc cgtcccattt ttataagaaa attctctcaa acttgactgg tcaaattgag
    21841 tcatcaagtc tttaatatcg tttaaattca tacttatcta ttctcccaac gtttgaaagc
    21901 aagaactgca ttgtggcctc caaaaccaaa agtatttgaa atagcgtatg gaatttcttt
    21961 ctccaagcct tgtccataaa cgacattagc ttcgatataa tctgatactt cacttgtccc
    22021 agctgtcatt ggtacaaagt tatgacgcat agcttcgatg gtgacgatag cttctactgc
    22081 acccgcagcc cccagcaaat gtcctgtaaa agacttggtt gatgatacag gtacttcctt
    22141 accaagaaca gctacgatag caccactttc tcctttttca ttggcaggag ttgacgttcc
    22201 gtgagcattg acataggcta cttgctctgg agaaatctca gcttcttcca aggctagttt
    22261 gatggccttg atagctccct gaccttctgg atgtggagaa gtcatgtggt aggcatcaca
    22321 agtatttccg taaccaacca cttcagccag gatagtagct ccacgttttt cagcgtgttc
    22381 aagactttct agaaccaaca tccctgaacc ttcacccata acaaacccat tgcgatcctt
    22441 atcaaatggg atcgaagcac gagttggatc ctctgtagta gagagagctg ttaaggcttg
    22501 gaaaccagcg atggcaaaag gtgtgataga agcttctgtt cctcccacca acatcacatc
    22561 ttggaaacca aacttaatgg agcggaaggc atccccaatc gcatcatttg atgaagagca
    22621 ggcagtattg atagatttac aaacaccgtt tgcaccaaaa cgcatggcta cattcccaga
    22681 agccatattt ggtaaagctt ttggaagagt cattggtttg acacgtttgg gtcctttttc
    22741 atgaaggcga agtacctgat cttcaatttc cttgattcca ccaataccag atgcaacgat
    22801 aacaccaaaa cgatccctat taagagcctc tacatcaaga ttggcatgat ttacagcctc
    22861 ttgggctgca tacaaggcat ataaagaata gttatcaaaa cggttggtat ctttttttac
    22921 aaagtattta tcgaacggaa aatcttggat ttctgccgca ttatgcacat caaagtcact
    22981 atgatcaaat tttgtaatgc caccaatgcc gattttccca gttgctaaac tattccaaaa
    23041 ttcttctggt gtatttccga ttggagatgt tactccataa cctgttacca ctactcgatt
    23101 tagtttcatt cttttcacct ctagctttcg ctacatactt aagccaccat caatggcaat
    23161 cacttgacca gttagataat cttggcctgc taaaaatact gtcaaatctg caacctgctc
    23221 tgcctgccca aattctttca tcggaatctg agctagtgta gcttccttaa tcttatctga
    23281 taagatagct gtcatatcag actcaatcat tcctggagca atcacattga ctcgtatatt
    23341 ccgactagcg acctcgcgtg ccacagactt ggtaaagcca atcaagccag ccttagaagc
    23401 agcatagtta gcttgaccaa tattccccat caaaccaaca acactagaca tattaatgat
    23461 agcaccttct ctggctttca tcatcggttt caagactgat tgtgtcatat taaaggcacc
    23521 agtcagattg accttgagca ctttttcaaa atctgcttct gtcatcttga gcataagagt
    23581 atcttgggta atccctgcat tgttgaccaa aacatctact gaacccagtt ctgcaatagc
    23641 ttgatcaatc atacgcttag cgtctgcaaa atctgataca tctcctgaaa tgggaaccac
    23701 cttgatacca tagtttgaaa actcagcgag caattcttct gagattgccc cacgactgtt
    23761 taagacaatg ttggctcctg cttgagcaaa cttgtgggcg atggcaagac caattccacg
    23821 actcgaacct gtaataaaga tatttttatg ttctagtttc atttttttcc tttcaaaact
    23881 tctacttatt ttagtctatt tttctaaaag tgctactaaa ctcgcttgat cttccacatg
    23941 agctaagtga gcagtttgat caattttttt aacaaagcct gacaagactt tccccggtcc
    24001 aatctctata aagttgctta tgcctgcttc ttgcatgacc ccaatacttt catagaaacg
    24061 aacgggttcc ttgacctgac gcgtcaagag ctgagcaatg tcctcttttt gcatcacagc
    24121 agcttctgta ttgccgacta ggggacaagt aaaatctgaa aaacttacct gagctagagt
    24181 ttcagctagt ttctggctag caggctcaag gagagcggtg tgaaagggac ctgacacctt
    24241 aagaggaatc aagcgtttgg cacctgcttc ttgcaaaagt tcaaccgctc gatcaactgc
    24301 aaccacttct ccagcaatga cgatttgtgc aggtgtgtta tagttggctg gagtaaccac
    24361 tccaagttca gaagcttttt gacaggcttc ttcaatgacc tctactggcg tattgagaac
    24421 tgctaccatc ttgccagagt cagcaggagc cgcttcttcc atataggctc cacgcttagc
    24481 taccaaggca accgcatctt caaaatccaa ggcgccgctt gccaccaagg cagagtattc
    24541 tccaagagac aaaccagcaa ccatatcagg ctgatagccc ttttcttgca ataaacggta
    24601 gatagcaacc gaagtcgcta gaatggctgg ttgcgtatag cgggtctgat tgagtttgtc
    24661 ttcttccgta tcgatgagat aacgcaaatc ataacctagt acctggctcg ctcgatcaat
    24721 cgtttcttta acaatcggat actgatcata gaaatcccgt cccatcccta gatactgggc
    24781 accttgacca gcaaataaaa aggctgtttt agtcatttct tacaactcct gtccagcgag
    24841 aggcttcttc ttgaattttc ttagcggctc cgtaatacaa atcttttagg atttcttcag
    24901 ctgtttcttc tttagaaaca agccctgcga tttgacctgc cataacagag ccaccatcca
    24961 catcaccgtg aacaactgct ttggctagag cacctgctcc catttgttca aagatttcta
    25021 aatcaggatc ttcttgctta aaggcatctt tttcagccag ttcaaaatct ctagtcaact
    25081 gatttttaat agcacgaaca gcatgaccaa agtgctgagc tgaaatcgta gtatcaatat
    25141 cccttgcttt taaaattttc tccttgtagt ttggatgggc attcgactct tttgcaacta
    25201 caaaccgtgt ccccacctgt acagcctctg cacctagcat aaagccagcc gcagcacctt
    25261 caccatccgc aattcctcct gcagcaataa caggaataga tacagctgtg gctacctgtc
    25321 gcaccaaagt catggttgtt aatttaccga tatgcccccc agcttccatt ccttctgcaa
    25381 taacagcgtc tgcaccgatt ttttccatgc gtttagctaa agcaacacta ggaacgacag
    25441 gaataacgat tatcccagct tcatggaaac gttccatata cttgcttgga tttcctgctc
    25501 ctgttgtgac aactttaaca ccttcttcaa taacgagatc cacgatatct tccacaaagg
    25561 gagataagag catgatgttg accccaaagg gtttatcagt caatgatttg attttatcaa
    25621 tattggcctt gacaacttct ttcggggcat ttcccccacc gataattcct aatcctccag
    25681 ccttggaaac agcccctgcc aaatcaccat cagcaaccca ggccatccct ccttggaaaa
    25741 taggatagtc aatcttcaat aattctgtaa tacgcgtttt catagtgcct ccaaccttcc
    25801 ttgcttacgt aatagttcga tttcaccata atttgacagt caaactatta cctaaacaag
    25861 agggagtggg tttctcccta ctccttctac ttaatattct gcttattttg cttgctcttc
    25921 aacgtaagca accaagtcac caactgtttt caagtcattt tctgcttcga tttggatatc
    25981 aaaagcatct tcgatttctg agattacttg gaacaagtcc aatgaatctg cgtccaaatc
    26041 atcaaaagtt gattcaagtg ttacttctga tgcgtctttt ccaagttctt caacgataat
    26101 ttcttgtact ttttcaaata ctgccatgat aggactcctt taaaataaat agttttttta
    26161 taacaatgtg ttcaccacat gattacctaa attgtaagaa tgagcgtgcc ccaggtcaaa
    26221 cctccaccga agcctgatag aagaacagtc tggctaccat ctaaagggat gagaccttgt
    26281 tctacacact ctgaaagtaa aatcgggata ctggctgcac tggtattgcc atattccatc
    26341 atattggctg gaagtttggc tcggtcaaca ccaatttttc tagccatctt atccaaaata
    26401 cggtcattgg cttgatgaag tagcagataa tccaagtctg tcacctctat aggagattca
    26461 tcaatagtct gcttgataga cttggctaca tctcgaatgg caaaatcaaa gactgtgcgt
    26521 ccatccatct tcaaaaatga atctgcactt tcttgatctg aaaatggaga atgcaaacct
    26581 gaatgcccat aagttaaaca ctcgctgcga cttccatcgc tattgagact ctcagctaag
    26641 aaatgctctt gctcgctagc ttctaacaag acaccaccag caccatctcc aaacaacaca
    26701 gctgttgatc gatccgacca atcgactgcc ttagagaggg tttcactacc aatcaccaag
    26761 cctttttgaa agcgaccaga agcgataaac ttttcagcag ttgaaagagc aaatacaaat
    26821 ccactgcaag ccgcggttaa gtcaaaagca aaggctttat tagcaccaat attagcttga
    26881 acacgagcag ctgtagaggg catcatcgaa tctggagtaa tggtagctag gatgataaaa
    26941 tccagttctt ttcctgttat tccagctttt gccatcagtt tcttagcaac ctctgtagcc
    27001 aaatcactgg tagattctgt tcttgaaata tgcctttgtc gtattcccgt tcgacttgaa
    27061 atccactcat cattggtatc cataatctga gccaagtcgt gatttgtaac cacttgctct
    27121 ggcacataat gagcaacctg acttattttt gcaaaagcca ttatttcaaa tcctccaaaa
    27181 attggtaaag attagtcaag cctttaccca tgacagcaat ttcttcctcg ctcatgccat
    27241 caataatttt ttctaccatg gccttgtgga agcgtttatg cagtctatga atcaagcgac
    27301 ccttctttgt caaatgcaga tgcaccacac gacgatcctg ttctgaccga actcgctcaa
    27361 tgtagccctt acgctctaaa ttgttcaaac ttgtcgtaac agttccaaga gttaccatca
    27421 actcttttga cacttgactt ggagtcacat ctggagcctt accgatgaca tcaatcgtat
    27481 gcatttcttt gatggagata tccttaaaac gactacctct caagttcact tcctcaatta
    27541 caaggacatt gttaaatata gatgttaaat attcattgat tcgttggtag tccatttttc
    27601 atatccctcc ttcttcaaaa aacttttaca atcaaaacat ttgacagaaa gaattatatc
    27661 aaaattcaaa gaatgatgca agtatttttt attttcctgt aaatttaggt cttcttctct
    27721 ccgaatgagc tcgcactcct tctttgaaat cctctgtttg agctaaggat ttctgtaggt
    27781 tcagttctaa agtagcgtaa ccctgccagt ctttaaattg gctctcccaa accaacttct
    27841 taatggcagc ataggaatta cttgaagcac gtcttaattt tttaagaagc tgttctctcg
    27901 tcttttcaag tttttcagct tcagaaacgc ggtaaaccaa cccccattct agggcttttt
    27961 ctgccgttaa agcctctcct gtcatagcta attgagcagc acgcgtcaca ccgatactgc
    28021 ggctcaagag atgaattccc cctgcatctg gagccaaacc aacaccaaca aaggcttgga
    28081 taaacttagc cttatccgtc gccaaacaga aatctgccgc aacagccata ttcgctgcgg
    28141 cacctgcaac agcaccgtca acttccatta aaacaggttt ggctatttgc ttgattttat
    28201 aagaaatcgt attgaccaac tctgcgattt ttgtcaatga tggaatatca tcctcatcca
    28261 ctgcccgctt catctctacc aaatctcccc caactgagaa gacctttcca ttggcattga
    28321 ttaagataaa atgcacagct ggattttctt ctgccaaagt cagagcttct aaaatctcct
    28381 cacacatggg aatatgaaaa ccatttgcga cctcaggacg gttcaaggta aggattgcca
    28441 agtcctcttc aagctgataa ataatgtgtt ccatcagggc tcctttttat tttataagca
    28501 gtttatactc ttcgaaaatc tcttcaaacc gcgtcagctt ccatctgtaa cctcaaaaca
    28561 gtattttgag ctgacttcgt cagtcttatt tacaacctca aagcagtgct ttgagcagtc
    28621 tgcggctagc ttcctagttt gctctttgat tttcattgag tgttaaatta tttcactgtc
    28681 aaagtatatc ttttttagga gcagaaagca agaaaaaatc gactgaaagt gtctcagccg
    28741 ataagaaagg ctcgctttag gctagaaagc atcttatttt cttcattgaa aaaagccttt
    28801 ctttctgcta taatcgtata aaatacttac tttaggagtt cttatgaaag ttgttaaatt
    28861 tggaggtagt tctcttgcct ctgctagtca attagaaaaa gttttaaaca tcgtcaaaag
    28921 cgattcagag cgtcgttttg tagtcgtttc tgcgcctggt aaacgcaatg ctgaagatac
    28981 taaggttacg gatgccctga ttaaatacta ccgcgactat gttgcgggta acgatattag
    29041 caagagccaa agctggatta tcgaccgcta tgctgctatg gttagtgaat tgggactaaa
    29101 accagctgtg ctagaaaaaa tttctaaaag cattcacgcc ttggccactc ttcctattga
    29161 agaaaatgaa tttctctacg atactttcct agcagccggt gaaaataaca atgccaaatt
    29221 gattgctgcc tactttaacc aaaatggtat cgatgcacgc tatatgcacc ctagagaagc
    29281 tgggattgtg gtcacaagtg aacctggtca cgctcgcatc attccatcaa gttatgacaa
    29341 gattgaagaa ttgacaaaca ccaatgaagt ccttgtcatt cctggtttct ttggtgtcac
    29401 taaggaaaat caaatctgta ctttctcacg tggaggatct gatattacag gttctatcat
    29461 tgctgctggt gtcaaagctg acctctatga aaactttacg gacgttgatg gtatctttgc
    29521 agcccaccct ggtattatcc accaaccaca ctcgattcct gagttgacct accgtgaaat
    29581 gcgcgagttg gcctatgcag gcttctcagt ccttcatgac gaggctcttc ttcctgccta
    29641 ccgtggaaaa attcctctgg ttatcaagaa taccaacaac cctgaccatc caggtactcg
    29701 tatcgttcta aaacacagta atgatgaatt tccagttgtg ggaattgctg gtgactcagg
    29761 ctttgtcagc attaatatgt cgaaatacct catgaaccgt gagattggat ttggccgcaa
    29821 ggttctgcaa atcctggaag aacttaacat cggttgggaa catatgccaa caggtatcga
    29881 cgatctttct atcattctcc gttctcgcca actaactccc atcaaggaag aagaaatcct
    29941 gcgtcagttg gttcaaaagg ctaaagtaga tcatgcagaa atcgaacacg acctttctat
    30001 cattatgatt gttggtgaaa aaatgaagag ccatatcgga gtgactgcta ctgcgacacg
    30061 cgctctatct gaaaacaaaa tcaacatcca gatgatgtct caaggttcta gtgaagtttc
    30121 tattatgttt gttgtcaata aagaccaaga gaaagcagca attaaagccc tctactatgc
    30181 cttttttgga gaaagtaagg aagactaagc atggctcaat cacttaacaa aacagtactc
    30241 ctcagtacga caggcacttc ctacctctct atcgctggga aagttgggaa attccttgtc
    30301 ggagatcagg ctttggaatt ttacccagat gtcaatgtcg aacaatttat ccagattcct
    30361 tggagccata tcaatcagat tggagccaat gtcactggac gcaaagtcag ccgccacttc
    30421 gaagtcttta cagacaaagg aaaattcctc tttgcttcaa aagactcagg tgccattctc
    30481 aaaattgcac gcgaaaaact aggcaatgac aaggtcgtca aacttccgac cctgattcag
    30541 acaattagcc aaaaatttaa aaatctattt gcaaaaaagt agaaacttta gtataatcat
    30601 agcaacggat aagtaggtta tcttcttctt tcagaaagtc tgcgggtact gcgagcagat
    30661 aggggggata ggtgaaattc taccgttagt aacaattaca tacacaatca agtgcacacc
    30721 tgtgaagttg gatggaaccg tggccctgcc actccaacgt tttgtcaggc gtgctttttt
    30781 cataaaggag ttcttatgtt agatatcaaa cgtattcgta cagattttga agctgtcgca
    30841 gaaaaattag ctacacgtgg tgtagatgct gctgtcttga atgaaatgaa agaaatcgat
    30901 gctaaacgtc gtaacatctt ggtcaaggtt gaaactctca aagcagaacg taacacagtt
    30961 tctgctgaga ttgcccaagc taagcgcaac aaggaaaata cagatgacaa gattgctgcc
    31021 atgcaaaatc tatctgctga ggttaaagcc ttggatgctg aattggcaga aatcgatgct
    31081 aaattgacag aatttacaac gactcttcca aatatcccag ctgacagcgt tcctgttggg
    31141 actgacgaag acgacaatgt ggaagttcgc cgttggggta ctccacgcga gtttgacttc
    31201 gaacctaaag ctcactggga tctcggtgaa gaccttggta tccttgactg ggaacgcggt
    31261 ggtaaggtaa caggcgctcg cttcctcttc tataaaggcc tcggtgctcg tttggaacgt
    31321 gctatctaca actttatgtt ggatgaacat ggaaaagaag gctatactga agtcatcaca
    31381 ccttacatag tcaaccatga ttctatgttt ggtactggtc agtatccaaa atttaaggaa
    31441 gatacttttg aactcagcga taccaacttt gtcttgattc caactgctga agttcctctg
    31501 acaaactact accgtgatga aatcttagac ggcaaagatc ttccaatcta cttcactgcc
    31561 atgagtccgt cattccgttc tgaggctggt tctgccggtc gtgatacgcg tggcttgatc
    31621 cgtttgcacc aattccacaa ggttgaaatg gtcaaatttg ccaaaccaga agaatcttac
    31681 gaagaattgg aaaaaatgac agccaacgct gaaaacattc ttcaaaaact caaccttcca
    31741 taccgtgtcg ttgctctctc tactggagat atgggcttct cagctgcgaa gacttacgac
    31801 ttggaagtgt ggattccagc acaaaacaat taccgtgaaa tctcaagctg ttcaaacaca
    31861 gaagatttcc aagcccgtcg tgcccaaatc cgttaccgtg atgaagcaga tggcaaggtg
    31921 aaactccttc ataccttgaa cggttctgga cttgcagttg gacgtacagt ggctgcaatt
    31981 cttgaaaatt accaaaatga agatggttct gtgaccatcc cagaagcact tcgtccatac
    32041 atgggtggag ctgaagtcat caaaccataa aaaataaggt ttagctattt ctagctagac
    32101 cttttttcgt aaccaaatca gataagcacc tagtacaaag aataaaatag ttaggcatat
    32161 aatggtttca gccaatacca ggtaatccag aaatggaagt ttcaaaattc cctgagccat
    32221 cttgagcgag gtcgctgtga taatggttgg gaaggtgagg gctgagaagg ctggttgaaa
    32281 accttgtttt aaaatgttgg gcagacgagt taaaacaaag aaaaagaagg attgagaagc
    32341 caaaatcatg acaatcaaga cccaagtcgg caggctggtt cctcctactc gaactagaga
    32401 agccaagagt agagagaaag gagcacagta gattccttct tgtccaagca aggctagtgg
    32461 gagtggatgt ttctttaaat cgctataaat aaggggatag agatagaagg tcaagagaaa
    32521 accaaaactc aaggtcgcat aggcaatttc gataatacct accagaggat aggtcaaggc
    32581 agccactgct atccccacat agagaaccgt ccagcttgga gtggcatgaa ccctccgccc
    32641 tggacaagca aacttgatgg taaaaccagc aatcaaggtc aaatccaaga gaaatgaaaa
    32701 ccaccaaatc ccttgtgcta ccaaaggaag ataagagaat acgcgaaaga cataggtcga
    32761 taaaatcatc ccagccatag gaaaggttgc cattcctgac aaaagagggg gcttggtcaa
    32821 ttcttgcttg gtttctttcc aattaaagag atgcagaatt agaaagtaaa tccataaaac
    32881 caaaccagtc agactaaaaa gatgggatag aaccggcaac gtatctaaaa taagatttcc
    32941 agctcctgcc aaacctagca aacaacctga aaatactaag gggagttttt tcatcctaac
    33001 ctccaataat catgttagtt tcagtataac ataaaagcgc ttaaatgagg atttaaaaaa
    33061 acgaagtccg attatttcag acttcatttt actcagatat gaattaggca taaggttgca
    33121 attctggatt aattggtgta ttagctaagt tgttggcata gttacagagg attgctaggc
    33181 tgacaccaaa aaccacatcc aaggcatttt gttgagtgta gccagcttct aaaaactcag
    33241 acaaggcttc atctcctaca cgacccttgg tattgataac tgccaaggta aacttagcta
    33301 gggtatccaa tttaggatct gtttcaattg gagtacgatt gcgaagagct tgaatcaagt
    33361 catcattcat ctggatttgt ttgatggaaa aggctgtgtg acctgcgaca cagaaggcac
    33421 aaccattggt cacggctgcc gtgatttgca ccacttcacg ctcaacgggt gtcaggctgt
    33481 tgcgacggtg gatagatgag acaatttggt aggcttctaa aacagtcggg gcattggcca
    33541 agagaccgat taggttggga atatagccat tgttgtcttt ttctactgtt tcaagaattt
    33601 ctttcacttc tgctggtgct gactctactg tatggatagt aaatgttgtc ataagatacc
    33661 tcttttctta ttattgacac taatattatt ggaaaatctt ataaaatcct gattcctaag
    33721 tttatctaag ataaagcttt attctctcat aagattttcg ttgttatatt agtttatcac
    33781 acttccaatc acttgcataa tatatattat atatcaggct gataaaaatt atttataggc
    33841 aaaaaaatca cacgagctgt gtgattccat tatttgttaa aatacttttt agtttcagca
    33901 ataacgactg gcgacaagac caagagggca atcaagtttg gcagagccat caaggcgtta
    33961 acgatatctg cgataatcca gaccatatcc aactcgataa atcctcctaa caagaccatg
    34021 agcacaaaaa acacacggta gagccagata aagcgagccc caaagaggaa ctcaaaacag
    34081 cgttctccgt aatagttcca acctagaatc gttgtaaagg caaaaagtac aaggaagatg
    34141 gtcaagaggg caggcccaaa gtgtgaaaag actgttgaga aagctgactg agtcaaggca
    34201 accccattca agtcaccact ccaaactcca gttaccaaga tggtcaaatc agttagagta
    34261 caaatgatga gggtatcaat aaaggttcct gtcatggaaa tcaaaccttg ctctactggt
    34321 tcatttgtct tggcagctgc aataggagca gaacccagac cagattcgtt tgagaacaca
    34381 ccacgcgcca caccattttg aatagccatc cgaacgctag caccagcaaa tccacctacc
    34441 gcagcaaggg gactaaaagc tgaggtaaag actaaagcga ttgtgccagg gatttttccg
    34501 atattaaaga aaataactgt aagagttcct aagatataaa tgagggccat aaaaggaaca
    34561 acagtagttg aaaccttaga aatagacttg agtccaccaa agactgcaat cgctacaaag
    34621 acagacaaga cgagagctgt gatggctggc gaaatcgtcg ttgtattttg gatagattct
    34681 gtaatcgagt tgacttgggt gaaggttccg attcccaaga gagcaaccaa tactcctgct
    34741 actgcaaaca aaacagcaag tggtcgccac ttttctccca tccctagaag gatatagtgc
    34801 atgggacctc ccgctactgc accatggtcg tccttggtgc ggtatttgat ggccaagagt
    34861 ccttccgcat acttggtagc cattccaaag aaagccgcca tccacatcca aaatagagct
    34921 cctggtccac caaccttgat agccgtcgca actcctatga tatttcctgt tccaacagtt
    34981 gatgccaagg ctgtacacag agctgcaaaa ctggatacat caccatgtcc cttatcctgg
    35041 ataaaaataa gctgaaaggc cttgggcaga cgcaaaacct gcaagagtcc tagccgcatg
    35101 gttaggtaaa tccctgttcc gaccaataaa atcaagaggg gcggtcccca agcaaaagca
    35161 tcgattgatt taagcaattc taacatttcc ttctcctatc gtttcaaccc caaaagaaag
    35221 agcacatgca agatacatgt actctggaat gcttagataa atgctaaaaa gcggtctatc
    35281 ctagctctgt ccttttacct gagagtttga gcagttgcct gccttgcccc ttcggtgcct
    35341 ttacggtctc tccagagttc cgtccattta cagtcatgga aaatcaaacg attccccact
    35401 tctattaaac ttcattcggt gttggtattt aattgattct aattttacaa aaaatgttgg
    35461 cttttgtcaa tgtgtttatt agtaaaaatt agttcaacag tttttacttt ataaagtcca
    35521 gaatactgct atcctttaaa agtgacaata gtcgcaccac tgcctccagc attttgtggg
    35581 gcatagccga aactcttgac atgtttgttt ctttgcaagt atttggtaac tccttcacgg
    35641 atgactcctg ttccgatacc atggatgata tcaacttgag ccatattgtt aagcaaggct
    35701 tggtcgatga aggtatctag ctcattcatg gcttcttcat agcgcttgcc tcgaagatcc
    35761 agtctagctt gaggtcctcg cccagaagtt cgtttcacaa cattgacctg tttcttcttg
    35821 actggttttt cttgctgggc ttgaacaaga tcaaactctt tctcttccaa ggtcatctta
    35881 atcaagccaa cttgggcttc ccagcgaccg tccttgagtt gactggtcaa ggtaccacgc
    35941 tgaccataac tgagaaccac gatatcatct cccacctttg gagctcgttt tttcttggcc
    36001 ttttgaagga ccttattttt agacaagtcc actttttcag gagccaattt tttcaacttg
    36061 accttggctt caatgatttc gtggggcttg agttgggatt tactgtggag atttttgaga
    36121 atctggtcac tttcacttaa ggccatatcc acaatctcag cagcctgttc acgcgccttg
    36181 ttaagctcgg tttccttttc acgattaagc tcgttgtaga gtttttttag cgcacggttc
    36241 atcttgagat tttcttgctc cacctcacgg atattgtcca aacgtttgcg gctttccagc
    36301 gtctgctctt ctaattgctc aatgatacga ttgacgtcat tgtcctgatc gatctgctga
    36361 ctggcatctc ctacgataac ttcagatagg cctagacgtt tggcaatttc aaaggcatta
    36421 cttcggccag gaacaccctg cataaagcga taggtcgggc gaagagttgc agtatcaaac
    36481 tccatactgg cattttgcac aaaggctgtc tcaataccgt aggccttgag ttctggatag
    36541 tgggtcgtcg ccatggtctt gatttgacgc aggcgaaggt cctccagaat agccatggca
    36601 agggctgctc cctcttgggg atcagtacca gcccccaact catccaaaag taagagtgaa
    36661 tgttggttga ccttgccaag aatatccacg atattggtca tatggctaga gaaggtagac
    36721 aagctctgct caatagactg ctcatctcca atatcagcaa agatttcttc aaaaatacca
    36781 acacgacttc ccttgtctgc taaaatcggc aatcctgact gggccatgac ctgtgtcaag
    36841 cccagagttt tgagcatgat ggtcttccca cctgtattgg gacctgtaat gacaatagct
    36901 gttaaatctt gaccaaaata gacatcattt gcgacggcat ttttgaccaa aggatggcag
    36961 acatggagca gttgaatctc ttgattttct gacagctgag gcacgactgc ttgtctttct
    37021 tggataaatc gaaccttggc acgaatcaag tccagatgac cgataatcca agcgtcatta
    37081 gcaatctcag ccgcatgagg gcggacacgc tcagaaattt cttggagaat gcgaagcatt
    37141 tcatagcgct catctgctcg cagactagca atttcttcgc tcagtttgac tacctcacgt
    37201 ggttcgatat agacggtgtt tccactagca gaaatatcat gaacgacacc tgcaatctta
    37261 ttgcggtagg tgtttttgac tggtaaaacc tgacggccat ttctgctagc aacaattcct
    37321 tccgtcaaca tctgcgcttt ttgcttgagc aagtcttgta aaacatcgcg tacctgactc
    37381 tcgctatcat gtatttttcg acggattcgc gccaattctt cactggcaaa attttcaatg
    37441 aaacccgcat cattaaaggc ctgaagattt ccttgtaatt gcggaaaatc atgtaatttc
    37501 tcaaaccaaa gggctaattc ttccaagctg acattttcca gattggcgta aaaactttga
    37561 agttctcggc tggtaagaag cacgcgtttc aagagtagga actcctcgat attgagatcc
    37621 gctcccatct ccaacctctt gcagactcct gcaatttcct tagttgagag aatagtaaaa
    37681 tgcggttgct cgacgaaaag agcctgcatt tctttcatct cagcaaaagc ctgtttgatt
    37741 ttatctgctt tggcagtcgg agccagctgt ctcaattgct ccaagccctg ctcggtcaac
    37801 aaatgaggct caaacaaggc cttgacctta tcgagctcta atgtttctaa tattttctta
    37861 ttcatcttta tttccttgtc tttgaatgtc taggtgtggt agctttttac attctgatag
    37921 attcgagtca aatctgtaaa caaagggcta ggaaaactcc tgcccttttt atccgattaa
    37981 atttgtcacc cagatttgtt tgagccaact ggttgttatc ggtatactct ggatgatgtg
    38041 ttttgcgacg atactctttt caagaggatt ttgtataact gccatgggga tggtcgccaa
    38101 gattgtcaag gccatttgca agacaaataa ggtcaccaac atggacaaga tacctgctga
    38161 aacttggaac aacttaccac ccagtttttt gctaggaatc aagtgtaaga gaagaccaag
    38221 caaacgacca atgctataga caatcccaaa tacaagcaag tagccgatac ctgcataaaa
    38281 gaccttatcc agctgaaaga gttgatccga tgggaaaaag aaagtcccct gaccttcctg
    38341 cgaatttgca taagggagca ataaatggaa ttgctctcca agccccttat aaaactggcc
    38401 agccataaaa gccgatgcca tggctgaaat caggtaataa acctgtaaga gcaggcctct
    38461 ccgatagccg atataaaatc cccaaaccaa gaccaataga agaaggaatg aaatcataag
    38521 gaatcctcaa tcttgctctg ttcttgctta caagtcacaa gcttgtgacg gagttcttct
    38581 agctcttgct ccttatcgtc aaattcaatc tcacggctga gctgagttga taaacagttg
    38641 actgccaaca aaagagcgat tgtttcatca tctgcgctag gcatttgttc tttaattgct
    38701 tggtattttt ctgtcgcaac cttagcgatt tcctccataa aaaggttatc atgttcgctt
    38761 gtcaaggtta acgatttttt cccgaatgta aatttgaatc gatttagatt tgccataaaa
    38821 ttcacctcac gatattatac caaaattcgc taattttgtc agtttttaca aattttactg
    38881 cttttgtggt acaatagaaa ctatggcaag tatcacactc acaccaagcg aaaaggatat
    38941 tcaggctttt cttgaacact atcaaaccag tctggctcct agcaagaatc cctatatccg
    39001 ctactttttg aaactacctc aagcaacggt ttctatctat acttctggaa aaatcttgct
    39061 tcagggtgaa ggggctgaaa aatacgccag tttctttggc tatcaagctg tagagcaaac
    39121 cagcggacaa aatcttcctt taattgggac agatgaggtg ggaaatggtt cctactttgg
    39181 tgggcttgca gttgtggctg cctttgtcac acctgaccag cacgactttt tacgaaaact
    39241 cggtgtgggg gattctaaga ctctgaccga ccaaaagatc cgtcagattg ctcctattct
    39301 caaggaaaaa atccagcacc aggcactcct tctctcaccc agcaagtaca acgaggtcat
    39361 cggagaccgc tacaatgctg tttcggttaa ggttgccctc cataatcagg ctatctatct
    39421 cctccttcaa aaaggtgttc agcctgagaa aattgtgatt gatgccttta ccagtgctaa
    39481 aaattatgac aagtacttgg cacaagaggc caatcgtttc agcaatccta tcagcttaga
    39541 agaaaaggct gagggcaaat acttggctgt cgcagtttct tctgtcattg cgcgtgatct
    39601 ctttctggaa aatcttgaaa atttgggacg agaactgggt tatcagcttc caagtggagc
    39661 tggaacggct tctgacaagg tggctagcca gattttgcaa gcctatggta tgcagggact
    39721 caacttctgc gccaaattgc actttaaaaa cactgaaaaa gcgaaaaaac gcttagaaag
    39781 gtaagttatg aattcactta aaaatttctt aaaagagtgg ggattgttcc tcctaattct
    39841 gtcattacta gctttaagtc gtatcttttt ttggagcaat gttcgcgtag aaggacattc
    39901 catggatccg accctagcgg atggcgaaat tctcttcgtt gttaagctcc tccctattga
    39961 ccgttttgat atcgtggtgg cccatgagga agatggcaat aaggacattg tcaaacgtgt
    40021 catcggaatg cctggcgata ccattcgtta cgaaaatgat aaactttaca tcaatgacaa
    40081 agaaacggac gagccttatc tagcagacta tatcaaacgc ttcaaggatg acaaactcca
    40141 aagcacttac tcaggcaagg gctttgaagg aaataaagga actttcttta gaagtatcgc
    40201 tcaaaaagcc caagccttca cagttgatgt caactacaac accaacttta gctttactgt
    40261 tccagaagga gaataccttc tcctcggaga tgaccgcttg gtttcgagcg acagccgcca
    40321 cgtaggtacc ttcaaagcaa aagatatcac aggggaagct aaattccgct tctggccaat
    40381 cacccgtatc ggaacatttt aagagaccta agaggccgag aatcacaaat ctcagcctct
    40441 tcttctatcg tgagaagtga ttgtttattg acaaatactc aatgaaaatc aaagaacaaa
    40501 ctaggaagct agccgtaggc tgcttaaaac agtggtttga ggttgtggat agaactgacg
    40561 aagtcagctc aaaatactgt tttgaggttg cagatggaag ctgacgtggt ttgaagatat
    40621 tttcgaagag tataaaataa aaacaatccc aactctcacc tattcatgca aaggaatttt
    40681 atggaagttt atttttcagg aaccattgaa cggattattt ttgaaaatcc cagcaatttt
    40741 tatcgcatcc tcctcctaga aatcgacgat acggacgcag aggattttga tgattttgaa
    40801 atcattgtca caggaaccat ggctgatgta attgagggcg aagactatac tttttggggg
    40861 caaattgtcc agcactccaa gtatggagaa caactgcaaa tcagtcgtta tgatcgcgca
    40921 aaaccaacta gtaagggatt ggtcaagtac ttttcaagta gccatttcaa ggggattggt
    40981 ctcaagacag ctcagaaaat cgtagatacc tatggcgaaa ataccattga tgaaattttg
    41041 caacacccag aaaagttaga aggcatcgca ggactctctg ccaaaaatcg cgaggctttc
    41101 gtctccactc tccgtctcaa ctacggaacg gagatggttt tggccaaact agccaactac
    41161 ggcattccca acaaactagc ctttcagatt caagactttt acaaggaaga aacccttgat
    41221 gtggttgaaa attatcccta ccagctggtt gaggatatca agggtttggg ctttacaatt
    41281 gctgaccaac tagctgagga actaggcatc gaaagtcagg ctcctgaacg cttccgcgcc
    41341 ggtctagttc acagtctttt tcaggcctgt atggaaacag gagacaccta tgttgaagca
    41401 cgggatttgc tggaacaaac ccttactctc cttgagtctt cccgtcccgt agaactagac
    41461 cccagccaag ttgcccaaga gctctcctac ctgatcgaag aagacaaggt tcagcagatt
    41521 gataccaaga tctttgacaa cagcctcttt ttcgctgagg aaggtatccg cagtcacttg
    41581 attcgtatcc ttgaaaaagg agaacagaag agacaagatt tagaaactat tcaaaagcat
    41641 atcactactg tcgagcaaga actggggatt gagtatgata acattcaaaa acaagctatt
    41701 tgtgacgcta tccagaacaa ggtctttatc ctgacaggtg ggcctggtac tggtaagaca
    41761 actgttatca atggaatcat cgctgtttat gcccttttag aaggacttga cttcaggaag
    41821 aaaagcaatc tgcccattct tcttgctgct ccaactggtc gagctgctcg tcgcatgaat
    41881 gaattgacag gtttgcctag cgcgaccata catcgccact tgggaatgac aggtgacgat
    41941 gataccagtc atctggaaga ttacctagat gctgacttta tcatcgtgga tgaattctct
    42001 atggtagata cttggctgac caatcaactc ttctccaata tctcttctaa cagtaagatc
    42061 ctcatcgtag gtgacagtga tcagctacct tctgtcagtc ctggacaggt tctagcggat
    42121 ctgcttcata ttcctttgat tcctcagact cgcttggaaa aaatttatcg acaaagcaaa
    42181 gaatcaacca tcgtcaccct agctagtcag attcgacagg gcatcttgcc agctgatttc
    42241 acccaaaaaa aagctgaccg ttcctacttt gaaattgcta gtggccatat tcctgccacc
    42301 attgaaaaaa tcttaggtgt cgccctcaga aatggtattc ctgcccgtga tatccaagtt
    42361 ctggctccta tgtaccgagg gacggcaggg attgatgcta tcaatcagct catgcaagac
    42421 ctgctcaatc ccccacaaaa agatcaactc agttttgaag ctcctcagtg ccactatcgt
    42481 aagagagaca aggtcattca tttggttaac gatgctgaaa tcaatgtctt taatggggat
    42541 ttaggagcta tcacagacct gattcctggt aaatacaccg aatcgaaaca agacgagatt
    42601 gtcattgatt ttgatggtaa tgaagtctct tacccccgta acgaatggta caagattcgc
    42661 ttggcctatg ccatgagtat tcataagtct cagggaagtg agttcccagt tgtcatccta
    42721 ccgattacta gtgctagccg acgtatgctg gagcgaaatc tcatctacac agccattaca
    42781 cgtgccaaaa gcaaactcat cttactaggc gaattacaag ccttcgacta tgctacccaa
    42841 cacatcggaa ctgcccgaaa aacctatctg attgaacgct tcagtgatct actggagaat
    42901 gttgaagaaa agcaacaagc tgtctctgaa acagtcacat caagtgcctc tgaacaatcc
    42961 tacatcctaa ccgaagaaaa ctgggacagc attccagcca tgattgggat tacagacaca
    43021 gacctcaaag agatttttgg aaaatagtac atcagaaaac ccaccaattc aggtgggttt
    43081 tctgtttatt aagattattt tactgttgct gtgcttgtga tcaattcaac agcttttttg
    43141 atagtgatat catgtttcaa catgtcagct gaaagcaagt tttgaacttg tgcaacttcc
    43201 atgttgtagt ctgctgccaa ttgctcaact tctttttgga tttcttcttc tgaagcatca
    43261 aatccttcag ctttggcaac tgcttcgata acaaggttag tcttagtacg tgactcagct
    43321 tctgcttggt attggttgtg aaggtcttct tgagtagttc cagtgatttg gaagtacatg
    43381 tcagggttga tcccttgacg ttgcaagttc ccaaggaatt catttactga acggtgaact
    43441 tcttcatgga tcatttcttc tggaagttct acgatttcag cgttttctac agctgtatca
    43501 attgctgcac cttcaactgc atctttgtaa gcttcttctt tagcagcagc caattctttg
    43561 cggtattttt ctttcaagtc agcaagtgtt tcaacttctt catcaatgtc ttttgcaagt
    43621 tcatcgtcaa gagctggaac ttctttagct tttacttcgt ggatagttgt cacgaattta
    43681 gcttctttac ctgcaaggtc ttctgcttgg tagtcttctg ggaatgttac gataacatca
    43741 acggtttcgc cagctgagtg acctaccaat tggtcttcga aaccagggat gaattgacct
    43801 gaaccaagtc caagtgagaa gttttcacct tttccaccgt caaattcaac accgtcgata
    43861 gaaccaacga agtcgatcac aacagtgtcg ccgttttcag cagcagcttc cttgataacc
    43921 aattcagcca gattgttgcg ttcgcgttcg atacgctctt caacatcagc gtcagttact
    43981 tctttttcta catcaactga tacttcaagg tttttgtagt cacccaattt tacttcaggt
    44041 tttgtaacga cttcagcagc gataacccag tcttgacctt tttccattga agttacgtca
    44101 atttttggtt gggcaaccac ttcaagacca gcttctttta cagctgcttc ataagcgttt
    44161 ggcaaaagag cgttcataac gtcttggtaa agtgattctt caccaaattt tttgtcgaag
    44221 ataggacgtg gaaggtgacc tttacggaaa cctggaacat taagagattt cttcactgac
    44281 ttgaagacac ggtccaattc tggtttgatt tggtcttgag agatagtgaa agtcaagaca
    44341 ccacggtttg tttctttgtt ttcaaatgat acagacattc tgtcatttct ccttaaaatt
    44401 ttttaaatac agtctattat aacattttct ataaataaaa tctagactaa tgcagccaat
    44461 tatagacaac aagccttttt cctaactaaa acactcataa agtatagaca attttagact
    44521 actttggata tcttttggtt agtcattttc caaaactaat ttatctaatt tttcagt
//
LOCUS       DAVHKZ010000014        42768 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000014 DAVHKZ010000000
VERSION     DAVHKZ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42768
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.014"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VVO74_000937"
     CDS             complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VVO74_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU5694979.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNKARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
     gene            complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VVO74_000938"
     CDS             complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VVO74_000938"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU5694980.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEVDYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VVO74_000939"
     CDS             complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VVO74_000939"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU5694981.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPKLEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKTQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3790..5058)
                     /locus_tag="VVO74_000940"
     CDS             complement(3790..5058)
                     /locus_tag="VVO74_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU5694982.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5178..5546)
                     /locus_tag="VVO74_000941"
     CDS             complement(5178..5546)
                     /locus_tag="VVO74_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU5694983.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5539..5805)
                     /locus_tag="VVO74_000942"
     CDS             complement(5539..5805)
                     /locus_tag="VVO74_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU5694984.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5873..9382)
                     /gene="mfd"
                     /locus_tag="VVO74_000943"
     CDS             complement(5873..9382)
                     /gene="mfd"
                     /locus_tag="VVO74_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU5694985.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9383..9952)
                     /locus_tag="VVO74_000944"
     CDS             complement(9383..9952)
                     /locus_tag="VVO74_000944"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU5694986.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     KADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10023..11138)
                     /gene="ychF"
                     /locus_tag="VVO74_000945"
     CDS             complement(10023..11138)
                     /gene="ychF"
                     /locus_tag="VVO74_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU5694987.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLIESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYESEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11222..11416)
                     /locus_tag="VVO74_000946"
     CDS             complement(11222..11416)
                     /locus_tag="VVO74_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU5694988.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11481..12617)
                     /gene="dnaN"
                     /locus_tag="VVO74_000947"
     CDS             complement(11481..12617)
                     /gene="dnaN"
                     /locus_tag="VVO74_000947"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU5694989.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12776..14137)
                     /gene="dnaA"
                     /locus_tag="VVO74_000948"
     CDS             complement(12776..14137)
                     /gene="dnaA"
                     /locus_tag="VVO74_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU5694990.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14350..15108)
                     /locus_tag="VVO74_000949"
     CDS             complement(14350..15108)
                     /locus_tag="VVO74_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU5694991.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNYFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15166..16347)
                     /locus_tag="VVO74_000950"
     CDS             complement(15166..16347)
                     /locus_tag="VVO74_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEU5694992.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16530..17009
                     /gene="rlmH"
                     /locus_tag="VVO74_000951"
     CDS             16530..17009
                     /gene="rlmH"
                     /locus_tag="VVO74_000951"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEU5694993.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEELSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17053..17126
                     /locus_tag="VVO74_000952"
     tRNA            17053..17126
                     /locus_tag="VVO74_000952"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17087..17089,aa:Arg,seq:tct)
     gene            17292..17417
                     /gene="comC"
                     /locus_tag="VVO74_000953"
     CDS             17292..17417
                     /gene="comC"
                     /locus_tag="VVO74_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEU5694994.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17438..18763
                     /locus_tag="VVO74_000954"
     CDS             17438..18763
                     /locus_tag="VVO74_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU5694995.1"
                     /translation="MDLFGFGTVIVHFLIISHNYHLICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIATFLFPLGLYSYFRWIKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFS
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18760..19512
                     /locus_tag="VVO74_000955"
     CDS             18760..19512
                     /locus_tag="VVO74_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5694996.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19564..19635
                     /locus_tag="VVO74_000956"
     tRNA            19564..19635
                     /locus_tag="VVO74_000956"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19597..19599,aa:Glu,seq:ttc)
     gene            19641..19714
                     /locus_tag="VVO74_000957"
     tRNA            19641..19714
                     /locus_tag="VVO74_000957"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19675..19677,aa:Asn,seq:gtt)
     gene            complement(19755..20297)
                     /locus_tag="VVO74_000958"
     CDS             complement(19755..20297)
                     /locus_tag="VVO74_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEU5694997.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20475..21242
                     /locus_tag="VVO74_000959"
     CDS             20475..21242
                     /locus_tag="VVO74_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEU5694998.1"
                     /translation="MIGISLIPALYNIIFLSSMWDPYGQLSDLSVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSKKTTTLSNI
                     QSTAAYQSLTSEQQTGISDSVSQNSTDSIQSAQSIVALVQGLQGSLENLQNQSSNLST
                     LKNQANQVLPITSTSLIGLSSGLTEIQGAVTSKLVPASQLIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21327..21734
                     /locus_tag="VVO74_000960"
     CDS             21327..21734
                     /locus_tag="VVO74_000960"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694999.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNIIFAKLPSGRH
                     PESRWPWLKSRAEINGIIAVLAGILVYGGVLLV"
     gene            complement(22104..24656)
                     /locus_tag="VVO74_000961"
     CDS             complement(22104..24656)
                     /locus_tag="VVO74_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU5695000.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQALKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISITSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTYKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24718..26340)
                     /locus_tag="VVO74_000962"
     CDS             complement(24718..26340)
                     /locus_tag="VVO74_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU5695001.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26546..27571
                     /gene="trpS"
                     /locus_tag="VVO74_000963"
     CDS             26546..27571
                     /gene="trpS"
                     /locus_tag="VVO74_000963"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU5695002.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27723..29201
                     /gene="guaB"
                     /locus_tag="VVO74_000964"
     CDS             27723..29201
                     /gene="guaB"
                     /locus_tag="VVO74_000964"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU5695003.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSINEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29252..30349)
                     /gene="recF"
                     /locus_tag="VVO74_000965"
     CDS             complement(29252..30349)
                     /gene="recF"
                     /locus_tag="VVO74_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU5695004.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSKSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(30352..30720)
                     /gene="yaaA"
                     /locus_tag="VVO74_000966"
     CDS             complement(30352..30720)
                     /gene="yaaA"
                     /locus_tag="VVO74_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU5695005.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30879..32129
                     /locus_tag="VVO74_000967"
     CDS             30879..32129
                     /locus_tag="VVO74_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU5695006.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32126..33409
                     /locus_tag="VVO74_000968"
     CDS             32126..33409
                     /locus_tag="VVO74_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU5695007.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSNRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33451..34272
                     /locus_tag="VVO74_000969"
     CDS             33451..34272
                     /locus_tag="VVO74_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU5695008.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34283..34828
                     /gene="pgsA"
                     /locus_tag="VVO74_000970"
     CDS             34283..34828
                     /gene="pgsA"
                     /locus_tag="VVO74_000970"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU5695009.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34825..35652
                     /locus_tag="VVO74_000971"
     CDS             34825..35652
                     /locus_tag="VVO74_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU5695010.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35637..36476
                     /locus_tag="VVO74_000972"
     CDS             35637..36476
                     /locus_tag="VVO74_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU5695011.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36469..37263
                     /locus_tag="VVO74_000973"
     CDS             36469..37263
                     /locus_tag="VVO74_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU5695012.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37322..38140
                     /gene="mreC"
                     /locus_tag="VVO74_000974"
     CDS             37322..38140
                     /gene="mreC"
                     /locus_tag="VVO74_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU5695013.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38140..38634
                     /gene="mreD"
                     /locus_tag="VVO74_000975"
     CDS             38140..38634
                     /gene="mreD"
                     /locus_tag="VVO74_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU5695014.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38728..39906
                     /locus_tag="VVO74_000976"
     CDS             38728..39906
                     /locus_tag="VVO74_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU5695015.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40130..40909
                     /gene="rpsB"
                     /locus_tag="VVO74_000977"
     CDS             40130..40909
                     /gene="rpsB"
                     /locus_tag="VVO74_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU5695016.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGHQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            40988..42028
                     /locus_tag="VVO74_000978"
     CDS             40988..42028
                     /locus_tag="VVO74_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU5695017.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEDGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42274..42597
                     /gene="tnpB"
                     /locus_tag="VVO74_000979"
                     /pseudo
     CDS             42274..42597
                     /gene="tnpB"
                     /locus_tag="VVO74_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
BASE COUNT        13404 a         7361 c         7878 g        14125 t
ORIGIN      
        1 tttcgtcatt catttttgac tttacttcat cataggatag tgcatgagat tcctcttcta
       61 ctgcttcagg catctttcct gtttcgtaaa gagctttaat ttgtgtacta tccaatgttt
      121 cgtatttcaa taatgcttct gcaattaact tgtgagtttc acgatttgac tgaataattt
      181 cagcagcttt atttcgtgcc ttatttaata atgaacgaac ctcttcatca atttcataag
      241 ctgtttgttc tgaaattgat ttttgaggat tctgtgcacc aaacatagca tggtttcctt
      301 catattgtac tgggccaagt ttttcactca taccgtactc tgtaaccatt gcacgtgcca
      361 tttgtgtcgc ttgttcaaag tcgtttgaag ctcctgtagt ttggacatta aagataattt
      421 cttcagctac acgtccaccc attaagccag ccaattgctc tttcatatct tctttagata
      481 gaagcatttg atcctcttta ggaagtgcaa tcatgtatcc gcctgcacgg ccgcgtggta
      541 caattgtaac cttatggaca acgcgagcat tcgacaagac tagaccaaca atggtatgtc
      601 ctgcctcatg gtaagcaacc aattctcgtt ctttttgtga aactgtctta tctttcttag
      661 aaggtccagc aataactcta tcttctgctt catcaatatc tgaagcatca attatcgatt
      721 tattgcgacg agcagcaact aaagctgctt cattcaagac attctctaaa tcagcaccaa
      781 caaagcctgg agtttgttga gccactaatt tcaaatcaac atcttctgct aaaggcttgt
      841 tcttagcgtg aactttcaag attgcttcac gacctttaac atcaggacgg ccaaccaata
      901 cttttctatc aaaacgtcct ggacgcaaaa gggcaggatc aagtacatct gaacggtttg
      961 tcgcagcgat gacgataatc ccttcatttc cctcaaaacc atccatctca atcaaaagtt
     1021 ggttcaaggt ttgttcacgt tcgtcattac ctccgccgag accaactcca cgttgacgtc
     1081 caacagcatc aatttcatcg ataaagatga tagctggtgc tgcttttttg gcatcctcaa
     1141 aaagagagcg aacacgacta gctccaactc cgacaaacat ttctacaaag tcagaacctg
     1201 agatactaaa gaatggaaca cctgcttctc cagcgactgc cttagcaagc aaagtcttac
     1261 ctgtccccgg aggtccctcc aaaagaacac ctgctggaat acgggctcca agttttgtga
     1321 atcgttttgg atcttttaag aactcaacaa cttcaactag ttcttgtttt tcttcctcag
     1381 ctccagcaac atctgaaaat cttactttaa tatcttcttt atttgctgct ttagccttac
     1441 tacgtccaaa actcattgga ttacggccat tgcctcctcc catatttccc atcatagaga
     1501 ataggaagaa gaatagaatt ccaaatggca caatggatac gagtagatta atccatatac
     1561 cacttgaact ttcatgctta acagttactt ctgctttatg gtcagtagca agtttttgca
     1621 attctgatac ggtagtatct gcaggaagaa tagtgctggt aaatttctct accttagtaa
     1681 cagatggcgt gaaaaactga atacctgttc cttctttact tgttttagga tttttataga
     1741 caccagaaac ttcgataaca ctaccatttg gttggtaagt taattctttt acattaccat
     1801 cggtaatttc ttgtaccaac tcagtatagt tgatttgctg acttcctcct gagttattcc
     1861 cagaatagaa atactggaat cctgtcacaa ggaaaaagat aaataataac catagaaaag
     1921 gatttttaat taaaccatta ttttgttttt tcattaaaga ttattctttc taatttgaat
     1981 acacttcctc tttcaatact ccaatataag gaagattacg ataattttct ttgtagtcta
     2041 aaccataacc tactacaaac tcatttggga tagtaaagca ggtatagtct acctcaattt
     2101 ctacaacacg tccttctggt ttatccaaca aggttgcaat tttaacagaa gctgcttctc
     2161 tttctttaaa catatctcgc aaattcttca aagtttgacc tgtatcaatg atatcttcta
     2221 caaatagaac atgtcttcct ttgatatctt gagtcacatc ttgtttaata ttgataacac
     2281 cactacttgc tgttccacca tggtagctag aaaccatcat gaagtccatt tcaatatgtg
     2341 tatcaatatg tttgaccaat tcagccataa aaggaataga tccttttaaa atcccaacta
     2401 agattggatt ttttcctgca tagtctttag ttaattgagc acctagtttt ttagctgctt
     2461 ctgtaatttc atcgtgtgaa acgaggactt ttttaatatc gttttctaac attttttacc
     2521 tatctatttt ttctatataa agtacagtgt tcattatatc atttttcgtt tttttactca
     2581 aattattggt cgcaattccc aaaattgaga caatttcacc aaattgctca ataataagag
     2641 cagagtttct cttttccata gggattttca aatcaataaa taaacgtctg agtttttttc
     2701 tatgcccatt ttgaatcaaa acatctcctg tttttcgatg acgaatgtgt atggatgttt
     2761 cacgtgaaac aggtatttgt tgaattaatt caccttctaa tggaagtcca aaggaaaata
     2821 aatatccttg ataagctacc tgattttgat agtgtaacac aagttcatct tccttttcat
     2881 cagcctgcgg actgatttta caaatctgaa actgttggta ctcttttatc aattcatagc
     2941 catttttaat cggatgacga tactggcttt tagattttaa aatctgctga acttcagcaa
     3001 actgagtttt tgtaagattc aaatctggaa aacgattcag ataagtttga agtaaaactc
     3061 tttgtgtaga ctcagagtaa gaaaataact gctgtaaatc ttccacatta atattgttag
     3121 ataattcagc tattgccaaa tcataatcta aaatttcatt gccaatgcct aagattgcat
     3181 ccctaaatcg aggattttct ttttccaatt ttggtaagta agaatttcga atacgatttc
     3241 gaaaataatg attctcctga tttgatgtat cttcaaagtg aaaaattgat ggaaagtctt
     3301 ttttctgaaa atgcaagaag ggacgaatga tttctatctc tccgactact tgcttctcct
     3361 taattcctga tagatagcgc aagcgagttc ctcgaatcaa gcgcatcaaa atcgtttcca
     3421 cctgatcatc agcatggtgg gcagtgacta aagctgtcgc acctgtcttt ttcatgacct
     3481 cttgaaaaaa atcataacga aaatttcgtg cacgcgcttc tgaaaattct cctgaaaaat
     3541 tgctgatata aataggaagc tctgcttcag cagccaactt ccttaattcc ttttcttccc
     3601 aatctgattc aattctctgc ttatgattca catgagccag aatcaattca atctctaact
     3661 ctttttgata agtagacaat accttaaata gaaacataga atctaatcca ccagaaagag
     3721 ctagaaccgc cttagcatgc tttttgaaat atcccttctt gagaaaatga tttaaaaaat
     3781 ctggttccct cattttagaa cctcataaac atccttggct atcttagaaa tcgtatcata
     3841 atcagaattc ttagtgaaaa tagaaagaat aaatggagaa tctgcataga caacacccgt
     3901 atcatgctta aattcatccg catctccaat tttatgagct actttaacag aaacaccttt
     3961 ggcaattcgc tgactatcaa aatctgtttt agtcaaagac tctagcacaa atccattttg
     4021 attataaata gcttccataa acttcccggc catcttagaa gaaatcaatt tttcttttgg
     4081 atcccaatca tctcccataa tggcagacat cttggatttg aatgtggcat cagattggtt
     4141 tgaaatgtaa tatcccaata gattatgagc tacattatca gattcttttg atactttcgt
     4201 aattaaatcc tttaaagaat attctttatt atcttctttt ttaggaagac taccacttcc
     4261 ctctggttta taagaacctg gaaaatcatt gactgcagat acgtatttta cagtcgtatc
     4321 taactgataa agaccctcat ttattttttc ttgcgtataa tagagatagg agagtttcaa
     4381 aacgctggct gcatacatct tttcatcttg attgatacca gcttcttttc cagtagtcag
     4441 ttgcttaaca taaatagaga aagaatcttt ctgatatttt tcagataaca tttcttgaac
     4501 tttactcatc cgattatctt cttcagaagt tgattcttta gctacccatc cagcctgatc
     4561 aatatgtaga aattctcttc cttctacaaa catggtcttg tcgattgata cttgcgaata
     4621 agctgataag gatgatttca cttcttttaa atcataagga ctattgtaca gtttaaagtc
     4681 agattctaac catgcttttt ttattgttgg agttacctct gattgatcat ataaaaatcg
     4741 tttgtccgca gctataaatt gatgatttga tagcttaaat actggaattc cttgtttatt
     4801 taagcgccac tcggttattt gaaaacttgt tttgggagtc aatttcccag attccactac
     4861 taaatcttca ttcgcataaa caggaacctc tccataaacc atgggagaac ttaatttttc
     4921 tctaaaataa ataccaaagt cagattgtga aaggtaataa atttctttcg aagtatagac
     4981 gacttctttt tctgtgctaa cgacttttga aatggtcaaa aaacttggta gcaacaaaat
     5041 aattaagaat ttacgcattc ttcctttcct tttcttcttg taaacgcaat aattgatttt
     5101 tatcagtcaa ttcttccagc ttttcatctg acaaactcaa aaattgctct attacgtcta
     5161 ataaattttc cattttatca cctttgaagc aagtcaggaa tcgtataaac tttttccctc
     5221 gacttagaat aatagtactt cgctcgtgta tatttagcag cataatcttc atctttcaac
     5281 ttggtagcaa atgctgtttc cttatccttt tcatcactca aagtttgata ctgagtttgc
     5341 aagtctgcta attgctgacg tctttggagt aattgctgat aactctgcgc caaattaaaa
     5401 gttggcaaga taaataatag cataatcaaa atcaataccc cccccataaa acgattccgt
     5461 ttttgtcgtt ctttcatcag gtagcgacga cgttggtatt cattttgaat aaaagaatta
     5521 ttcaattgta caatattttt agacattttc ttctacccgt gtttcactga taatttcata
     5581 cattcctgct gcatcttctt tttttgtact atctttcatc tctagtactt ttacaagcag
     5641 caacttattg ccaaagcgaa tttcaacttg gtcattaact ttcaagtccg ttgaactttt
     5701 ggccaagatt ccattaacct tgattctacc tttatctgct acttcctttg cgactgtacg
     5761 acgcttgata attcgcgata cttttaaata tttatctaat ctcatcctta ttacctcaat
     5821 ttattattgt accattttta tctattttta tctattttat agaagaaaaa tatcaaatgg
     5881 aattttcttc cttaaactct tttatctcta ataaactttc tccaaaaatc agcagacctt
     5941 ctaaaatttc ataatctttc ttattttgga catcaaatac aagctccatt aatcccttat
     6001 tctcagcgat gcctgctttt aagttcgtta cggataaagc tttaaaataa tcttgagcta
     6061 aaaacagtcg ttgagtgact ttttcaaatt gaattgtaat tttattatct tttctttcca
     6121 cacgttgaac aaagaccttg tccaagtatg atttgaccaa accaatctct aaaagatagg
     6181 ctactacatc tgggtattct ccaaaacggt ctatcaactc ctcttgtaac tcttcataat
     6241 tgacacggtt gtcaatttga cgaattttct tgtaaatttc aatcttatgt cgttgatcag
     6301 aaatataagt atcaggaaga taggcatcaa tttgcaaaat caactcagca ttccctttgg
     6361 ttcttgtgtt agcgttagca ttaccgtttc gtttagcaat agcttcctct aataactgcg
     6421 aatacaattc aaaaccaaca gaatcaatga aaccagactg ggattttcct aaaagatttc
     6481 ctgctccacg aatcgaaaga tctcgcattg caatcttaaa gccagagccc aattctgtaa
     6541 atcctttaat cgcttctaat ctcttttcag agacttcact gattgatttt tctggacgat
     6601 acatgagata agcataagca atacgattac tacgaccgac tcttcctctt aactgatata
     6661 aggttgacaa gcccatatgg tccgcatttt caataaataa agtattagca tttggaatgt
     6721 ccacccctgt ctcaataata gtagtcgtca ccaagatatc gtattgtccc tcaataaagt
     6781 ctaatagagt attttccaac tggacttcac tcattcgacc atgaacatat ccaatcgaag
     6841 cctccggaat caactcctgt aattctgaaa ccttctgaac aattgtgtca actttgttgt
     6901 aaagatagta aacttgacct ccacgctcca tttcacgcaa gacagcatca cgaatgacac
     6961 tatcattctt ttccaaaaca taggtctgaa caggatagcg attagtcggc ggagtttcaa
     7021 taacagacaa atctctgatt cccagcatag acatatggag ggtacgaggg attggcgtag
     7081 cggtcaaggt taggacatcc acttgtttct tcagttcttt caaagtttcc ttatgcttga
     7141 caccaaatcg ctgttcctca tcaataatca tcaagcccaa atcagcaaac acaacatctt
     7201 ttgacaaaac acgatgtgtt ccaatcaaaa tatcgacttg accgtttttc aatttttcaa
     7261 gtgttgcagt ctgctctttt ttacttctaa agcgactcaa cacatcaaca ttaactgcaa
     7321 aattttggaa tcgttcctta aaattcgtat agtgctgttg cgctaaaacc gtcgtcggaa
     7381 ctagaatgac aacctgtttg tgatcattga ctgctttaaa ggctgcacgc atagcaactt
     7441 cagtctttcc aaaaccaaca tccccaacta aaagtcgatc cattggctga gaagcctgca
     7501 tatccctttt gatttcctca atactacgaa gttgatcatc cgtttcaaca taagggaaag
     7561 catcatcaaa ggcatcttga tcatcatcat cagctgagaa agcaaaaccc ttcaactgac
     7621 tacgttcaga gtagagtttg attaaatcat cagctatatc ctctacctgg ttcttaacct
     7681 tttgcttggc ctttttaaaa tgaccgtcat ttaatttatt gagttttgga gctttaccat
     7741 cacttgaaat atatttggac agtagatgaa tctgttccac ggggatagaa atttgatcac
     7801 cattttggta ttggacactg acataatcgc gatgaattcc cttgatttca atggtttcaa
     7861 ttcctagata ttgaccaatc ccatggatat gatggacaac atagtcccct ttttcaagtt
     7921 cattgtaatc ttttaatctc tctgcatttg aaacatgttg tcttcgaaaa cgacgcttta
     7981 atttcttttg aaaaatctca tgttcagtta tcaataaaat cttttcatct acaaaatgaa
     8041 aaccatgtct gagattaccc tctattaagt ttacagattc tttacagata tttgtcttat
     8101 ctctagaatc caatttaatc tgatattcct ctaacatatc ctccaatgtt ttacttccca
     8161 ttgaattgct agactgcaga ataatggtgt aatccatttt tttatatcgt tcaatttctt
     8221 cttttagaaa agaaaactga ttgaaaaatt cctgcatagg atattgattg aattgataaa
     8281 ttttgtcaaa tttgagattt cctaaaccct tttgaagatt agagaaaaag gtcactggac
     8341 tttgtttttt atagatttgt tcaatatcag aaaaatactg catatcagaa aatgctttac
     8401 tattctgtaa ttcttctgta aagtactgcg ctaagtctct ttcaaagact tcatactgat
     8461 tcatcaattt ttgataatca tcaaagaata ttggagtatc tttttcaata taatcaaaga
     8521 cagtccatgt cttatcatag cacaaagata aaaacttccg agagtctgca tgactttgtt
     8581 tttggtgaaa acttgaaaga atttcttcta ggtatgattt caaaataggt gataaagttt
     8641 ttgaaatttg tttttctaaa gctgactgtc ctcgttgata atccttttct ctcaaaagca
     8701 tatcactagc tggaaagata gtgagttctg tcttattttc tttcgataat tgtgtttcta
     8761 cttcaaatga cctgatacca tcaatttcat caccaaaaaa ctcaattcga caaggttcta
     8821 actgggatat ttcaaaaata tctaaaatat ctcctcgaag actaaattcg ccctgagttt
     8881 gtacttgagt aacttttcga tagccatttt cctttaactg atggataaac gcgtgttgat
     8941 catattcttc accaactgag atttttacaa tactatcttt gaatgcattg ggagacggta
     9001 aaatcaatcg acttgctgcg atattacaaa ctaaaatccc tttcttagat gaatcagtca
     9061 aaaaacgcaa ggcttcaacc cgtgaaataa ttttttcctg tgaagacatc aaaaactcca
     9121 ccataggagc atcatctacc aaaaatggat agacgagttc ctcacccaag atagatataa
     9181 gatcactaac aagtccttct gcttctccat aagttgacgt caataacaca atcctatctt
     9241 ctttttctaa actgcttgca attgcaagag ccttagtaga tgttgataaa ccaagtatta
     9301 gttgtctttt cttatcagtt aaattttgat gccatttttt aatctgatca ttttctgaga
     9361 ataaatctaa taaggtcacc atttatccgt tatacctctg cattgttttc tcaaaatttt
     9421 tctcttgtaa atagtagttt acagaatcgt caactttgtc aacagactgt aaaataccga
     9481 tataatcatc cctgtcaaac ttactcaaaa catgatgaac aactgacata ccatttttag
     9541 gtcttccaat tccaatctta acacggttaa agacctgagt tcctatatgt tgaataatag
     9601 acttgatacc attatgacca cctgctgagc cttttgctct taaacgaatt ttcccaactt
     9661 ccatgtcaag atcatcgtaa atgataagta aatcgtcaat atccaaacca tagtaagtta
     9721 ataaagcatg aactgctttt ccactttcat tcataaaggt cgttggttta accagataaa
     9781 ttttttctcc atttaggaaa aaggatgcta ggtcagcttt aaatatctta tcgtgtgtaa
     9841 aagtgacatt ctgtttcttc gctagttgat caatcaacat aaaaccaaca ttgtgttttg
     9901 tttcaaaata tttatcccct ggatttccca agcctacaag taatttggtc atttattttt
     9961 cctttcaaaa gccaaaaggg ttggaatttt tttccaacct aattgacacc atttattaat
    10021 ttttagacat taaagcggaa ttccatgata tcgccatctt gaacgatata ttcttttcct
    10081 tcttcacgca agcgtccagc ttcttttacg gccttttcag attcgtattt cactagatcc
    10141 tcatatgaca tggttactgc acgaataaag cctttttcaa agtctgagtg gataatacca
    10201 gctgcttgag gagccttcat accacgtttg aaagtccaag cgcgaacttc tttttcacca
    10261 gctgtgaagt aagttcccaa tccaagcaag tggtaagctg cacgcgtcaa cttatctaca
    10321 cctgattcta tcaaaccaat ggcttcaaga aactcttttt tatcttcatc atccaattca
    10381 gaaatttctt cctcagcacg cgcagaaata acgactactt cagcattttc tgtcgctgca
    10441 aattcacgaa tttgtttgac atagtcgata gagtcaggtt ctgaaaccac atcctcgtcc
    10501 acattagcta cataaagaac tggtttagtc gtcaaaagga aaagaccttt gacaaccttt
    10561 tgttcctcat ctgtaaattc aatggtacga gctgatttcc cgtcttctag gactggttta
    10621 atcttttgaa gaacattgaa ttctgctact gattctttat ctttttgcgt acgtgccatc
    10681 ttttctacac gcgcatatcg tttattgact gattctaagt ctgcaagaat caattctagg
    10741 ttaatggtgt caatatctgc aagtggatcc acaaaggcgt cttcacgtcc ttgctcgcgc
    10801 atcacatttt catcatcaaa agcacgaact acgtgaacaa tcgcatctac ttcacgaata
    10861 ttggccaaga atttattccc tagcccttct ccttttgaag ctccttttac aatccctgca
    10921 atatccgtaa attcaaatgt tgtgggaact gtctttttag gagttatcat ttcagttagt
    10981 ttttgtaggc gttcatctgg aacttccacc attccaacat ttggatcaat agtcgcaaat
    11041 gggtagtttg ctgcctctgc tcctgctttt gtaattgcat taaatagtgt tgatttacca
    11101 acgtttggca aaccaacgat acctgctgtc aaagccatat ttctcattct ccgttttcat
    11161 ttcaatccct aatattataa cacaaaaagg gataaagtgc taaccctcta actaagggtt
    11221 ctcagtcaat aattttattc atttttcgct caaaatcata tcgccccatc atgacaacat
    11281 gctcacaatt actgcatttt attttgatat ctgctcctac acgtgtaatt tcccaacgat
    11341 tagccttttt accagtcgac ttgattgtac aagcgtgtga ttttttcatc tcaacaaaat
    11401 ttccaacttg atacatacta ctctcctttt ctttttcgat tatatcataa aagaggcgag
    11461 ccaggctcaa cctctttcac ttaatttgta cgaactggtg taatgagctg catgaagtct
    11521 tcgtcagtat ctgctggcac aagagtaaat ggacgaacag ctgagataaa gctaatagtc
    11581 accttttcgc tatttaaagc tttaagagaa tcaatcaagt aagttgggtt gaaactaatg
    11641 gtcaaatctt caccagtaac ctgatcagta tcgatttctt cgtttacttt accaacttct
    11701 ggagagtgaa catgggcgct aacaacccca tccttaattt caagtttcac agtaccattt
    11761 tgagtcgcac ttgataaaag acgggcacgc tccattgact ggcgtaagtt taccacatta
    11821 aaagtaatag tagtgttaaa gtctgttgga atcaagcgat ctgtatcagg atagtttcct
    11881 tctaggagac gagtatagaa gctaatattt tcgcttctaa agaggatttg attattggca
    11941 aagaaaatct ctacagtttc gatatcatct gtaaataccg ctgaaaattc gcgtagagaa
    12001 cggctaggaa ttacgacatc aaaatcatca ctattttttt caagagtcaa ttttttctgg
    12061 cttaggcgat gagagtctgt tgcaactgtt tttaactctt tgtgttgact caatacgaag
    12121 tggacacctg ttaaaatcgg acgactctct tgtgtacttg cagcaaaggc tgtttcatta
    12181 ataattttct tgagtaattt tgtttcaagt attaaaggag tgcttgctga aatttcttgg
    12241 attcgtggat attgttcgct atcttttcct tttagggtaa tttctgattt gccactggtt
    12301 aaaacaattt gattttgttc aatttcttta aaatcaagag ttacatcagg taaactagat
    12361 actacattga taaagaaaga agcttcaaga aggatcgaac ctaaagaagt aattaacaaa
    12421 ccagcatctt catttttttg agaaataaaa ttttcaattg aaatttgacc atttgaacca
    12481 attaaagtaa taccttcatt ggtcacgtca atttttactg ttgataaaat aggaatggca
    12541 tttttagaac taatagctct cttagtagta tttaatgctt gtagaaataa atttttatta
    12601 attgaaaaat gaatcatgga ttctccttta tttattttta gtattagaaa gataatagta
    12661 ataatagagt ctgtgaaatc tgtggaaaac agcctttaaa caagtcatat caagtttttt
    12721 agcttgttta aaaaatgtgg ataaaaaaga taaaaaacta aaagttatcc acaaattatt
    12781 tgattttctt tttgattgat tcaatttcta aacgtaaatt atcgtcttga tcaatcaaag
    12841 attttatttt ggcatgggca tgaatgactg tggtatgatc ttttccccca aattccttcc
    12901 caatttttgg aagactatta tctgttagtt ctctagataa atacatggct acttgacggg
    12961 ccaaaacaat attttgaagg cgtctacttc ccttcatttc tttgatacta acaccataaa
    13021 agttaccaac ttcagtttgg attttatcaa ttgggatgac gagcatttgg ctaacatctt
    13081 gtttgcgggc tctaatggct tctgcagcaa tatcaatagt gatatccttg atttttttta
    13141 ctctggcaat taaagtgatg tcgttgatgg ctccctcaag atctcgaaca tttgaatcaa
    13201 attgcccagc taggtattct agagtatcac tttggaaatt gtagcctaaa tgttccgttt
    13261 tactttgtaa aatggcaata cgtgtttcaa agtcaggggg tgtgatagtt tgtgtcaatc
    13321 cccaactaaa acgcgtgaca agcctctcct cgagcccttc tagatgtttt ggactacgat
    13381 cactcgttag gacaatctgt ttttgcttgt catgaagggc gttaaaggta ttgaaaaatt
    13441 cttcctgagt tgcgactttt tttccgctga gtgactggat atcatcgatt aacaaaagat
    13501 caagactacg ataggtcttt ttaaactttt ccatttcccc aagtcttagg tgatcaagaa
    13561 agtcattaat aaagctttcg gcagggatat atttaacacg cgcattagga atatttttta
    13621 gaatttcatt tccaatagcg tttaataagt gagtcttacc aaggcctggt cctccataga
    13681 taaaaagagg gttataggtc agagccaaat cttcagagac agctaaagcg gctgatacag
    13741 cccaaacatt tccatcccct tgaataaagt tatcaaaggt atacttttct tttaatcccg
    13801 tatctgaata aggaatagat actaactttg gactatagtc ataaagagtt aaatttgtag
    13861 cttcttcaac ttgtgagcta gtcgtatctt gaggtttggt gaaaatatag tggggagtta
    13921 tttcagcgtc ataaatttca aaaccagcta ctacaataat atcttttagt tgtttttccc
    13981 agaccatttc catttcagag cgaggtagaa atatagtggc aacattttcc tctaccttga
    14041 tgagttcagc ttgaatagca tagaaatcat acatggatcg agtcagtctt tcttgtgcaa
    14101 attctaatat acgattccaa aattgttttt ctttcaatcc tttctcctcc tttactattt
    14161 aaaagtttaa tactagagat attttaccat agatagcaag aattttccac aagctgtgaa
    14221 aaataatcca caatgttact aaactttatc cacaggttgg ggataaaaga agaaattatt
    14281 gatttattaa gctttttatc gaaaaacata gtggataacc ttgtgagata aaaaaataaa
    14341 agaacagcct tatttcaggc tgttgataat tctactatat tcttcttgat ttgaaaaaga
    14401 aataatgatt tttccactgt cttttttaga tagtttaatt tctacatcta atccgagtag
    14461 ttttcttaac tgtttttctt cattttgtat gaaataatta gttttttgct gtttcttttg
    14521 ttttttctct gtcagaagag cttctaactt ccttacagaa atatcttctt ctataatccg
    14581 ttgaaagaaa tagtcttgtt gttccttatt taacccaact agggaacgcg catgggcttg
    14641 tgatagtttg ccattttcta cttctgagag aatctgttct ggcaaggaaa gtaaacgaat
    14701 ggagttgctg atatatggac gagacttgcc catcttatct gcaatttcag catgggtgaa
    14761 tcctttctct acgagagatt cataggcgcg tgcttcttct attgggttta aattttctct
    14821 ctgtaaattt tcaataatgg actggaccat catctcttgg tctgaaatct gtttaacaac
    14881 agctgggata gaccgtagac cagctaaaag tgaagcccga tagcgtctct ctcctgcaag
    14941 gatttcataa ccaataacag gagattgacg aacaataatc ggttgaatga ccccattttc
    15001 tttgatagac tgtgctagtt catctagttt ttctctatca aattcttttc ggggttgata
    15061 gggatttttt tgtatatctg tgatagaaat catttcaaat ttttccatga ttctacacta
    15121 acacatcttt tctcttatgt aaagctttct ttacatagat gtcaattaag attctaaatc
    15181 acctgaactc ttgttaagtt tgatagaggt agtttcttct ttcccgttac gatagtaggt
    15241 tatcttaatg gtgtctccga tagaatggtt gtaaagagca ctttgtaagt ctgttgatga
    15301 agcaatctct ttgtcatcta cttttgtaat tacatcgtat ttttcaaggt gaccattggc
    15361 aggcatatta ctttgtaccg aacgaacaat tacaccagat gtaacattac ttggaatatt
    15421 gagtcttctg atgtcgcttg tactcacatt agataaatta accatctgga ttcccaaagc
    15481 tggacgcgtc acttttccgt ttttttctaa ctgttcaata atattgatag catcatttgc
    15541 aggaattgcg aaaccaagac cttctacaga tgttcctcca tttgtagcaa ttttacttga
    15601 ggtaattccg ataacctgcc cttgaatatt gatcagtggg ccgccagagt tacctgggtt
    15661 aatagcagta tcagtttgga tggcttttgt agaaatagct tgtccatctt ccgattttaa
    15721 ggatacattt ctattgagac tggatacgat accttgagtg acagtatttg catattcaga
    15781 acctaacggg ctaccgatgg caatagcagt ttctcctaca gttaacttac tagaatcacc
    15841 aaactcagct actgttgtca ctttttctga agagattttg acgacagcaa tatcagagaa
    15901 agtgtcagct ccgacaattt ctccaggtac tttagtccca tctgacaatc gaatatctac
    15961 tttgctggcg ccatttataa cgtgattgtt ggtgacgatg taagcttctt tatcattctt
    16021 tttataaata actccagatc cttcactaga gattcgctga gaatctgtgt cagtatcatc
    16081 attgccaaat acgctatttt gtctgtttgc cgaataagta ataacagaaa caacagcatc
    16141 ttttactttg ttaacagcct gtgttgttga attttcgttc ttataggcag tttgtgtaat
    16201 agtactattg ttgttagagt tgtttacact acttttttga gttagttgag ttattgaaaa
    16261 actacccaag gctccactaa aaaagctaat gacgataacg actaataatt gaaaccattt
    16321 tttgtaaaat gtttttagat gtttcatatt tgcctccata tgtttgaatt actgaaagta
    16381 taaactgact agcttaatta taacttaaac acaaaagttt tacacaaact gtggataact
    16441 cttttgaaac tgtgattttc ttaattgaaa tctatttttt attttgtgaa taagatgtga
    16501 aaaaatagag aatatgttag aatagagtca tgaaaattaa agttgtaaca gttgggaaac
    16561 tgaaagaaaa gtatttaaaa gatggtatcg cagagtattc aaaacgaatt tctagatttg
    16621 ctaagtttga aatgattgag ttatcagatg aaaaaacacc agataaggcc agtgaatcag
    16681 aaaatcaaaa gattttagaa atagaaggtc agagaatttt atcaaaaatt gctgaccgtg
    16741 atttcgttat tgtgttagcc attgaaggga aaactttctt ctcagaagaa ttgagtaagc
    16801 agttagaaga aacttctata aaaggatttt ctactcttac ttttattatt gggggaagtt
    16861 taggattgtc atcatctgta aaaaatagag ccaatctttc tgtcagtttt ggtcgcctaa
    16921 ccttgcctca tcagttaatg agactagttc ttgttgaaca aatctatcgc gcttttacga
    16981 ttcagcaggg attcccctac cataaataga aaattgactt ttaattgaat ttttggtaga
    17041 ataattgtgt taggtctcat agctcagctg gatagagcat tcgccttcta agcgaacggt
    17101 cgcaggttcg aatcctgctg ggatcaatat aatagcaaag ctgggaattt tcccggcttt
    17161 tttcttaaaa aagtacactt tgggagaaaa aaatgacagt tgagagaatt ttatctaaaa
    17221 cgaaattcca ttttgtataa tggtttttgt aagttagctt acaagaaaaa aacattttag
    17281 gagattttat tatgaaaaac acagttaaat tggaacagtt tgtagctttg aaggaaaaag
    17341 acttacaaaa gattaaaggt ggggagatga ggctgtcaaa attcttccgt gattttattt
    17401 tacaaagaaa aaagtaatga aataagggga aagagtaatg gatttatttg gatttgggac
    17461 agttattgtt cattttttaa ttattagtca caactaccat ttaatttgta aaggtcaaat
    17521 aaatagaaaa gaattattcg tttttggtgc ttatacatta ctaacagaaa tagtatttga
    17581 ttttccctta tatattctat atttagatgg gttagggatt gcaacatttt tatttccttt
    17641 gggcctatat tcctattttc gatggataaa acagtatgag agggatagag gactattcct
    17701 aagtttacta ctatctcttt tatatgagag cactcataac tttctgtccg taactttctc
    17761 ctctataaca ggagataatt ttgttttaca atatcatttc ccattctttt tcgttgtgac
    17821 ggtgttaacc tattttgtta cattaaaaat catttactat ttccatttgg aactagccta
    17881 ttttgacaag gactaccttt atcctttctt gaaaaaagta ttttttgctt tactattgct
    17941 acatattgta tctttcgttt cagatatggt aagtacgatt aaacatttga atagttttgg
    18001 aagtattttg tcatctattg tctttatctc tctccttttg accttctttg caatgaattc
    18061 tcataaagtt caaatggaga aagagattgc tttgaagcag aagaaatttg aacagaaaca
    18121 tttacagaat tacacagatg aaattgttgg tctgtataat gaaatccgtg gttttcgaca
    18181 tgattatgct ggaatgcttg tcagcatgca gatggcaatt gacagtggta atttacagga
    18241 aattgacaga atttacaatg aagttttagt caaagcaaat cataaattgc gttcagataa
    18301 gtacacttac tttgatttga acaacataga agactcagct ttacgaagtt tggttgctca
    18361 gtcaattgtc tatgctcgaa ataatggtgt agagtttaca ctggaagtaa aagatacgat
    18421 taccaagctt ccaattgaac tattggattt ggttcgtatc atgagcgttt tattgaataa
    18481 tgctgtcgaa ggatcggctg atagctataa aaagcagatg gaagtagcag ttattaagat
    18541 ggaaactgaa acagttattg tgattcagaa ttcatgtaaa atgacgatga ctccttcagg
    18601 agatctattt tccttaggat tctccactaa gggaagaaat cgcggagtcg gattaaataa
    18661 tgtgaaagaa ctactagata agtacaacaa tattatttta gaaacagaga tggaaggcag
    18721 tacatttaga caaatcatta gatttaagag ggaatttgaa tgaaagtttt aattttagaa
    18781 gatgttattg aacatcaagt gagactagag agaatattgg atgaaatttc gaaagaatcg
    18841 aatattccaa tatcatacaa gacaacggga aaagtccgtg aatttgaaga atacattgaa
    18901 aatgatgaag taaatcagct ttatttccta gatatcgata ttcatggaat tgagaaaaag
    18961 ggatttgaag tggctcagct cattcgtcat tacaatcctt acgctattat cgtctttatc
    19021 actagtcgat cagagtttgc gactctaacc tataaatacc aggtatcagc cctagatttt
    19081 gttgataagg atatcaatga tgagatgttt aagaagagaa ttgagcaaaa tatcttctac
    19141 acgaagagta tgttacttga aaatgaagat gttgtagatt atttcgacta caattacaag
    19201 ggaaatgatt taaaaattcc ttaccatgat attttgtata ttgaaacaac aggggtatct
    19261 cataaattgc gcattattgg taagaatttt gcaaaagagt tttatggtac catgacagat
    19321 attcaggaaa aggacaaaca tactcagcga ttttattctc ctcacaagtc atttttggta
    19381 aatataggca atatcagaga aattgatcga aaaaacttag aaattgtttt ctatgaagac
    19441 catcgttgtc ctatttcaag attaaaaatt agaaaattaa aagatatttt agagaaaaaa
    19501 tctcaaaagt gattgacaat tagcaagaaa ttgatataat ggttatatct gctacagata
    19561 gaaggtccgt tggtcaaggg gttaagacac cgccttttca cggcggtaac acgggttcga
    19621 atcccgtacg gactatttta tccgccatag ctcagttggt agtagcgcat gactgttaat
    19681 catgatgtcg taggttcgag tcctactggc ggagtataga taaaagggaa cacagctgtg
    19741 ttcctctttt tgtatcaatt tgtatcacca agcattttca taaggaagtc tgttatttct
    19801 tgagaacttt ctttttttcc atgtgcaatc caagtttggc agacaccaaa aagtgcatga
    19861 gttagataga tgctactata ttctaattca gtggtattta gattcagttg cataaatcgc
    19921 ttttgtaaat ctgtactaag catgatatga agtttatttc gtaagaaatt ttggatttct
    19981 ttagtcccat tttcagaaag aagggcagcc agaagtggtt ctgactctag atattcaaaa
    20041 acttctaaaa tagcgtctct tttgtgatga gcatgttttt gaaaaatata ttcaaatgta
    20101 tggaatagct tgctttgata gtgctcaatc atatcatact tatccttata gtgagtatag
    20161 aagctggaac gactaattcc ggctttttct actaatttga cagtagaaat tttatcaaat
    20221 ggctgttcca tcagtaattg taccatagca ttttcaatag ttcgctttgt ttttaagcgt
    20281 ttgttacttt cttgcatatt tcctccttgt aaataaatta gactatatgt ctaaaaatag
    20341 attttttatc ttgtaattta gattttttaa tgtataatct attatatcaa aattttagac
    20401 aatatgttta aaaaaggaga aactatgttt aaagaatgga aagcaattta aaaaaaacaa
    20461 cctttattat tgtcatgatc gggatttctc ttattccagc tctgtacaat atcatatttt
    20521 tgtcatcaat gtgggatcca tatgggcaat tgtctgactt atctgtggca gttgtaaata
    20581 atgataaaga ggcttcctat aatggtaata ctatggcaat aggaaaagac atggtgtcca
    20641 atttaaaaga aaataaaacc ttggattttc attttgtaga tgaagaggaa ggaaagaagg
    20701 gattggaaga tggcgattac tatatggtag tgactttacc aagtgattta tctaaaaaaa
    20761 caactacatt atccaatatt caatcgacag cagcttatca atcattgaca agtgagcaac
    20821 aaactgggat aagtgattct gtatctcaaa attcaactga tagtattcaa tcggctcagt
    20881 caattgtagc tttagtacaa ggtttacagg gaagtttaga aaacttacaa aatcaatctt
    20941 ctaatctttc gactttaaaa aatcaagcta atcaagtatt acctattact tctacttctt
    21001 tgataggatt gtcaagtgga ttaacagaga tacaaggagc tgttactagc aaattagttc
    21061 ctgccagtca gttgattgca tcaggtgtaa acgcatatac tacaggtgtt gataaagttt
    21121 ctcagggcgc aagtcaacta agtgaaaaaa atgccacctt gacaggtagt ttggataaac
    21181 tagtttcagg ctcaaacacc ttgacacaaa aatcttctag attgacagca ggagttggtt
    21241 aattacaatc aggatctggg caattagcag acaaatccag tcagttactt tcaggtgctt
    21301 ctccattaga gaatagagct aataaattgg cagatggatc tgggaaacta gcagaaggtg
    21361 gaacaaagtt aacttctgga ttggaagatt tacagacagg acttgcttct ttaggacaag
    21421 gactaggtaa tgctagtgat caactcaaat cagtatcaac agaatctaaa aatgcagaga
    21481 ttttgtcaaa tccactcaat ctttcaaaaa cagacaatga tcaagttcct gtaaatggaa
    21541 tcgcaatagc tccttatatg atatcagttg ctctttttgt tgcagcaata tcaacaaata
    21601 taatatttgc gaaattgcct tcaggacgtc atccagagag ccgttggcct tggttgaaat
    21661 ctcgagctga aataaatggt attatagctg ttttggcagg aattttggta tatggaggag
    21721 ttctattggt ttaactgcta atcatgagat gagaatattt attctcatca tccaaacaag
    21781 tttagtattc atgtctatgg tgaccacttt agcaacgtgg aatagccgta taggagcttt
    21841 tttctcactt attttgcttt tactatagtt agcatcaagt gcaggtactt atccacttgc
    21901 tttgacaaat gatttcttta gatctattaa tccctgttta ccaatgagct attcagtttc
    21961 gggattacga caaacaatct ctatcaacaa gtcattttcc tagctgtcat actagctcta
    22021 tttactggtt taggtatgct agcctatcaa cataagaaaa tggaagaaga ttaaaaaaat
    22081 cgaccgatta actggtcgat tttttatgcc ttagatgact ttcgtctgtg attatagatt
    22141 ccaaatagta agagagaagt aaaggaacag attgctccag taataaaacc attgggaatg
    22201 aaggaaagtg taatagttcc tttccccttg ggaatgtcaa ctttcataaa tccagtttga
    22261 gcttgtttaa tttctatttt cttaccatct tggtaggcag accaaccttt gtcataagga
    22321 atggtgaaga aaatagatgt atcttgttgg acatcatatg tagcaaaaac cttgttttta
    22381 taagttgata ctgtgacagg ttgttcttta attttttgaa ttgcctcggt gaaagttttg
    22441 gtatctaaac gatagaaggt aggagattca aatgatactt gtgaatttcc agggaaacta
    22501 acattgatat tgaaagtttt tttctcttta gtatatccta gattaaagaa ggagaagaca
    22561 ttatcagttg taaaagtctt tttttcacca tttacaagga tgtcaacctt cttttgttta
    22621 tcgttagaaa agtgaaggtt tatgaaagag agataaactt ggctgttttc tggaacttca
    22681 atttgatact ggattgctgc atcttcattt gaagaacttg tgatactaat caaatcatta
    22741 gtattttcta ttttttctgt tttttcataa ggtattggag aaaaataatc aaaattgacg
    22801 ttagcaagtt gatttaaaaa tgaggcctga ttatccaagg tatgttcatt gaacttgaca
    22861 tcattgtaaa cagattgact agcaactgca atcggaagag agtattgatt ttcatatagg
    22921 gtaagattat ctttttgata gatatcttta aagccatact tatcaatagg actgtctgag
    22981 atattgtact ggataccaaa taaactatca gccaaaatac tattatttgc atatcggaga
    23041 ttgagattag tcccagagga tttaaaacca agtttatcta aagtagagct tgatgaacga
    23101 tttcgaacag atgaaaattg agagattcca ttgtagttga atttcatact gtcatttcct
    23161 gtctgagttt gtagtttttc agtacgagta aattgatttc caatatatgt tgagaaagat
    23221 tccatagctg ggatatctcg actataagca cttcgagaag caaatcccca ttccttagca
    23281 attccgtcca tttgagatga agcatttaaa ctcatttcaa ccagtataaa taaagagatt
    23341 agaatggcaa atagattcac agatataaac tttttgataa ctgcaaggag taaaagagaa
    23401 tagacaacca aaaattcaag agtaagcaga atattcaaat ctgttaaaaa agaataatgc
    23461 gattttagat agatggtagc taaaaatcct gctactacaa gaaaaagcga aactaaaaaa
    23521 ttccagactt taagttcttt cagacgcttt aagacttctg ctgctgtgta aattaacaag
    23581 gtagagaaaa tccaagcata gcgatgtaaa aacatgtttg gagtatgcat gccttgccaa
    23641 aataagtcaa gagcttctat gtaaaagctt gcaattagaa atgcaaagaa tattacatat
    23701 atgagtttca cgtgaaactt aatagatttc agcgtaaaaa ataaaatggt caaaataaag
    23761 ggaaatagtc caacaaaaat cattgggatg gccccatact ttgttgtgtc aaaggaacca
    23821 atgaattgct tagcaaagag atcaagatac cagctacttt cagtttgaaa ctttgtaact
    23881 tcagtcaatt tttccccatg tgtctgtaaa tcaaatagag tgggaagagt cataatcaaa
    23941 ctagccatac cagctaaaaa ggagataact atgaaatcaa gaacagatga ttttcgagtc
    24001 ttaaagtccc acgaaatttg acagagatac cagaaaataa gaaacaatac tgtcatatat
    24061 ccaaaataat aattttgaat aaataagatt gacagacttg taaagtacaa taggagtttc
    24121 ttttcagtta tcagtagatg taaaccagtt ataattaaag gaatcaagat aaaaacatct
    24181 agccaggttt ttatctctaa ttgactgaca gtgaaactca tcagagcata ggaagtagat
    24241 aaggctagtt ttaaagcctg agggatagat tgaaacaatt tattcaaact aaaaaaggtt
    24301 gacagaccaa tcaatccaaa ttttaagaga gttgtcagat agatagcatc tggcatattc
    24361 gttagatcaa aaaagtaaac cagaggcgcg agaaaactac ccaagtaata actagatagg
    24421 gcatagaagt ttagccctag accacttgta aaggtgtaaa acagactact atttccatgt
    24481 aggatatttc gtaaggctac atcaaaaata acgtattgat gaaagccatc tcctaataga
    24541 ggagagttgt cgctattcca gtagatacct tgagatagat atactccaga cataatcact
    24601 acaggaatga tgaaagaaat aaaataggtt cgatatgttt ttaaaaatga tttcatgtta
    24661 cctcgtagaa tgatagaaaa ctcagttggt taacccaact gagttttgaa gttttattta
    24721 gtctttccaa agttctttaa cttttgcttg tacttctgca ttttctagga attcatcgta
    24781 ggtttcatcg atacggtcaa tgacgccatt tttagataag acaatgatat ggttagccaa
    24841 agtttgaata aattcgtggt catggctggc aaagatgatt gattctttaa agtttttcaa
    24901 tccatcattc aagcttgaga tagattccaa gtccaagtga tttgttggat catcaagtac
    24961 aaggacattt gattttaaga gcatgagttt tgaaagcatg acacgaactt tttctccccc
    25021 tgacaagaca tttacaggtt tgttaacttc atctccagag aagagcatac ggccgaggaa
    25081 gccacgtagg aaagtattgt catcttcttc tttacttgcg aattgacgca accagtcaag
    25141 aattgattct cctcctgcaa aatcagctga gttatctttt ggtaggtaag attgactagt
    25201 tgtaactccc cacttgacag ttccttcata gtcaatatct cccatgattg cacgaattaa
    25261 tgcagtcgtt tgaatatcat tttgtccaat aagtgctgtc ttatcatctg gacgcaagat
    25321 gaaactaata ttatccaaga tagtttcacc atcaatcttt acagttagat tttctactgt
    25381 caagagatca ttaccaatct cacgttccgc tttaaagttg ataaatggat atttacgact
    25441 agatggtaca atctcttcta gctcaatctt atcaagcatt ttcttacgtg atgttgcctg
    25501 ccttgactta gaagcattgg cagagaaacg agcaacgaat tcttgcaatt gtttaatttt
    25561 ttcttctgct ttagcattac ggtctgctag caatttagca gcaagctcag aagattcctt
    25621 ccagaagtcg tagtttccga catagagttt gatttttcca aagtcaaggt cggccatgtg
    25681 agtacaaact ttgtttaaga agtgacggtc gtgggatact acgataactg tgttatcaaa
    25741 gtcaatcaag aagtcttcta accaagtaat cgattggata tccaaaccgt tagtaggctc
    25801 gtccaagaga agaacatctg gtttaccaaa aagtgctttg gcgaggagaa cctttacttt
    25861 ttcaccgttg gccaattcgc tcatgttttg gtagtgtaat tcttctggaa tgtttaggtt
    25921 ttgaagtagt tgagaggctt cactctctgc ttcccaacct ccaagttcgg caaactctcc
    25981 ttcgagttcg gcagcacgaa ccccgtcctc gtctgagaaa tcttccttca tgtagatagc
    26041 atctttctct ttcatgatgc tataaagttt ttcatttccc atgataacga catcaatggc
    26101 acgttcatct tcgtagtcaa agtgattttg acgaagaaca gagagacgtt catctggacc
    26161 aagagagatg tgaccagtag taggttcgat atctccagct aaaattttta aaaaggttga
    26221 ttttccggca ccattagcac cgattaatcc gtaagtattt ccttctgtaa atttgatatt
    26281 gacatcatca aaaagtttgc gatcactaaa acgtagtgaa acatcagata ctgtaagcaa
    26341 tatttttctc ctatatgtgt aatatattta ttctactaga aaatacagaa atattcaaat
    26401 ttttatttgt caattttgtg taaattatat ttacagtatc ctttacacaa atctgtaaaa
    26461 agcaaggctg atttattttg ataaattacg gttatttcat taaaaaaatg ctataattga
    26521 aaggactata tcgaaggaga acaaaatgac taaacccatt attttaacag gagaccgtcc
    26581 aacaggaaaa ttgcatattg gacattatgt tggaagtctc aaaaatcgag tattattaca
    26641 ggaagaggat aagtatgata tgtttgtgtt cttggctgac caacaagcct tgacagatca
    26701 tgccaaagat cctcaaacca ttgtagagtc tatcggaaat gtggctttgg attatcttgc
    26761 agttggattg gatccaaata agtcaactat ttttattcaa agccagattc cagagttggc
    26821 tgagttgtct atgtattata tgaatctagt ttcgttagca cgtttggagc gaaatccaac
    26881 agtcaagaca gagatttctc agaaaggatt tggagaaagc attccgacag gattcttggt
    26941 ctatccaatc gctcaagcag ctgatatcac agctttcaag gctaattatg ttcctgttgg
    27001 gacagatcag aaaccaatga ttgagcaaac tcgtgaaatt gttcgttctt ttaacaatgc
    27061 atataactgt gatgtcttgg tagagccgga aggtatttat ccagaaaatg agagagcagg
    27121 gcgtttgcct ggtttagatg gaaatgctaa aatgtctaaa tcactaaata atggtattta
    27181 tttagctgat gatgcggata ctttgcgtaa aaaagtaatg agtatgtata cagatccaga
    27241 tcatatccgc gttgaggatc caggtaagat tgagggaaat atggttttcc attatctaga
    27301 tgtttttggt cgtccagaag atgctcaaga aattgctgat atgaaagaac gttatcaacg
    27361 aggtggtctt ggtgatgtga agaccaagcg ttatctactt gaaatattag aacgtgaact
    27421 gggtcctatt cgtgagcgcc gtattgaatt tgctaaggat atgggagaag tttataatat
    27481 gattcaaaaa ggtagtgaaa gagcgcgtga agttgcgggt caaaccctat ctgaggtaaa
    27541 aggggcaatg ggacttcatt actttaatta agtttatttt acaagaaact atcatttcta
    27601 tctcgaagaa aagatagttt tttatttacc cctgtaacat ttgacaaatt tttatagaat
    27661 ggtatgatag atacaatata aaaagagtca agctcaaaaa gaaagaaaag aggaaacttc
    27721 gaatgtctaa ttgggacact aaatttttga aaaaaggttt tacctttgat gatgtattgc
    27781 ttattccagc tgaaagtcat gtgttgccta acgatgcaga tttaacaact aaattggcag
    27841 ataatttgac tttaaatatc ccaattatta ccgctgccat ggacacagtt acagagagtc
    27901 aaatggccat tgctattgct cgtgcaggtg gtctcggagt tatccataaa aacatgtcaa
    27961 ttgctcaaca agcagacgag gttcgtaagg taaaacgttc tgaaaatgga gttattattg
    28021 atccgttctt cttgacgcct gaacatacaa ttgctgaagc agatgagctt atgggtcgtt
    28081 accgcatcag tggtgttcca gttgttgaaa cacttgaaaa tcgtaaattg gttggtattt
    28141 tgacaaaccg agatcttcgt tttatttcag attataatca accaatttca aaccatatga
    28201 ctagtgaaaa tcttgttact gctcctgtgg gtacggatct tgcaacggct gagagtattc
    28261 ttcaagagca tcgtattgaa aaacttccgt tggtcgatga agaaggcagt ctttctggtt
    28321 tgatcactat caaagatatt gaaaaagtta ttgagtttcc aaatgcggct aaagatgaat
    28381 ttggtcgtct tctagttgca ggtgcagtag gtgttacttc agatacattt gaacgtgcag
    28441 aggctctttt tgaggcagga gcggatgcga ttgttattga tactgcacat ggtcattctg
    28501 caggtgtctt gcgtaaaatt gccgagattc gtgctcattt cccagatcgg actttgattg
    28561 ctggaaatat tgctactgct gaaggtgcac gtgcccttta tgaagcgggt gtagacgttg
    28621 ttaaggttgg tattggacca ggttctatct gtactactcg tgtgattgct ggtgttggtg
    28681 ttccgcaagt aacagctatc tacgatgctg cagctgttgc gcgcgaatat ggtaaaacga
    28741 ttattgctga cggtgggatc aagtattctg gagatattgt aaaagcactt gctgcaggtg
    28801 gaaatgctgt tatgcttgga tctatgtttg ctggaactga tgaagctcca ggcgaaactg
    28861 aaatcttcca aggacgtaaa ttcaagactt accgtggtat gggatcaatt gctgctatga
    28921 agaaaggttc aagcgaccgt tatttccaag gttctatcaa tgaagcaaac aagctcgttc
    28981 cagaaggaat tgaaggtcgt gttgcttata aaggagcggc agctgatatt gttttccaaa
    29041 tgattggtgg tattcgctct ggtatgggtt actgtggtgc agctaacctt aaagaactac
    29101 acgataatgc tcaatttatt gaaatgtctg gtgctggttt gaaagaaagc catcctcatg
    29161 atgtgcaaat tactaatgag gcaccaaatt attctatgta aaaaacaatg aaaagaactc
    29221 cagtgaaaac aggagttctt ttacaatgtt gtcaatttcc atttacagca gctttaccat
    29281 cctgaatagt gaagatactt agattttctg gtagattttg aagatggtct aagcttgttg
    29341 ttgtgataaa ggtttggatt gattgagaaa tcgtttctaa taattttaat tgtctagtgt
    29401 tgtcaagttc actcatcaca tcgtcaagca gtaatatagg agattctgtg gtaatgcttt
    29461 ccattaattc gatttctgct aattttatcg agaggacgag actacgatgt tgaccttggc
    29521 ttccgaaact agcatccatc ccatttatat aaaaagaaat gtcatctcga tgaggaccga
    29581 caccagtatt ctttttaaat aaatctctgg atttactttt ttctaaagca attttgaaag
    29641 attcggataa gttttgtttg tcagttatat tgacagaaga ttgataggat attgacaact
    29701 cttcgatctg attagagagt tcaaaatgtt tcttacgccc aaatgattct agttttttta
    29761 tgaaatctaa gcggtgattc attacacgac atccataatc aactagctga tcatctaaca
    29821 cagaaaggaa tgtttcatct attttttgat ctgattttag gtaagtgttt ctttgcttta
    29881 ggatgtggtt ataattggtt aagtcagata agtagattgg cttaatttgc ccaagttcca
    29941 tatcgatgaa ttttcgtcga atcgaaggtg ctcctttaat tagttgtaaa tcttcaggag
    30001 caaataagac aacattcatg tgtcctacat aatctgaaag gcgtgcctgt tttaagtgat
    30061 taacttttgt tacacggcct ttttgtgtta gttcgatttc taggggaatg gatccagttt
    30121 ttttctgaac gagacctgaa agatgaagtt gttcctcatc aaaatgaatg agatttttat
    30181 ctgttcgagt tcgatgacta cgcgttaagg ctaaaaaata gatagcctct aacatgtttg
    30241 tttttccttg tgcattacgt cccaaaaaga cattcaattt aggattaaag tctattttcg
    30301 tttctttgta attacgaaaa gtcttgagag atagatgttg tagccacatg attatctacc
    30361 agggaatcgt ggagcttgtt ggcttttagg tgatgaagca ggtttcgatt tgtctttttt
    30421 aactccctta ttcatctttt tgacaagttt agcgatccgt tctttttcaa ctttatcagc
    30481 ttggtattca tcttgttctt cagaagtagg ttgtgtcaac aagatgtcaa tgttcatgtc
    30541 agggatgtca actttatcgc caatacgaag tttttttcca cgacgactct ctaattccct
    30601 attaaagtaa acagaatgtt cagagagaaa tgatttaata gctcctccgc tatgtgtaat
    30661 tccaagttct ttgagtagtg cttggagggt aataaattct tcaaataatt tgtattccat
    30721 aattcacctc aatctttggt attataccat attttcctaa aaatagtgag agagacagcg
    30781 agaaatgtaa gcgattttta tttcaaaagt gttacaggga acaagaaaat ttcaggtttt
    30841 cgtgatataa tagaagtctg tatataagga ggtaaatcat ggagttagtg catggaattt
    30901 caacacattt tatccaatca aaaaagttta aaacaaacaa aattaccgtg cgttttaccg
    30961 ctccattatc ccttgatacg attgcaggtc acatgttgag tgcaagtatg ctagagactg
    31021 ctaatcagat gtaccccact tctcaagatt tgaggagaca cttggccagt ctatacggta
    31081 cagatatgtc aaccaattgt ttcagaagag ggcaaagcca cattatagaa ttgacattta
    31141 cctatgttcg tgatgagttt ttaagtagga aaaacgtgct aacctctcag attttggaac
    31201 ttgtaaaaga aactcttttt tcacccgtag tagttgataa tgggtttgat ccggccttat
    31261 ttgaaattga gaaaaaacaa ttgctagcaa gtttagcagc tgatatggat gattcttttt
    31321 attttgcaca taaagaattg gataaattgt tttttcatga tgaacgtctt caattggaat
    31381 atagtgattt acgaaatcgt attttagctg aaactccaca aagttcttac tcttgtttcc
    31441 aagaattttt agccaatgat cgaatagatt tctttttcct aggtgatttt aatgaggttg
    31501 aaattcaaaa tgtattagaa tcatttggct ttaaaggtcg aaaaggagat gtgaaggttc
    31561 agtattgtca accttattct aatatccttc aggaaggtat ggttcggaaa aatgtgggac
    31621 aatccatttt ggaattaggt tatcattacc gttctaaata tggtgatgaa caacatttac
    31681 ccatgattgt aatgaatggt ttacttggtg gatttgctca ctctaagctc tttacaaatg
    31741 tccgtgaaaa tgctggatta gcttatacca tttcaagtga gcttgattta tttagtggat
    31801 tcttgaggat gtatgctggt atcaatcgag aaaatcgtaa ccaggctcgt aaaatgatga
    31861 ataatcaact gcttgattta aaaaaaggtt attttacaga gtttgagtta aatcagacca
    31921 aggaaatgat tcgttggtcg ttgttacttt ctcaagataa tcaatcttca ttgattgaac
    31981 gtgcttatca aaatgcctta tttggaaaat cttcagcaga ctttaaaagt tggattgcaa
    32041 agcttgaaca aattgacaaa gatgctattt gtagagtagc taataatgtg aaactacaag
    32101 cgatttactt tatggaagga atagaatgac aaaggttgtt tttgaagaaa aatactatcc
    32161 agctgtaaaa gaaatggttt atcgaactcg tttggccaac ggattgacag ttgctctttt
    32221 gcctaaaaag gaatttaaag aggtttacgg gagtgtcact gtacagtttg gttcggtaga
    32281 tacgtttgtc acagaagttg acggagatgt aaaacaatat cctggaggaa ttgctcattt
    32341 tcttgaacat aaattatttg agagagaaga ttctagtgat ttgatgtcgg cttttacgag
    32401 tctaggtgca gatagtaatg cctttacaag ctttacaaaa acaaactatc ttttttcagc
    32461 aacggattat tttttagaaa atttagattt acttgatgaa ttggtaacat cagcacactt
    32521 tactgaagct tccattttga cagagcagga tattattcag caagaacgag aaatgtacca
    32581 agatgatcca gattcgtgtt tattcttttc aactttagcg aatttgtatc ctggtacacc
    32641 tttagcaact gatatagttg gaagtgagga gtccatttcc caaatcaatc taactaattt
    32701 gcaagaaaat tttacaaagt tttacaaacc tgtaaacatg tctctgtttt tagttggtaa
    32761 ttttgatgtg gagcgagtac aggactattt tgaaagcaaa gaactgaaag attcagattt
    32821 tcaggaagta gcaagagaaa agttgttttt acagcctgta aagccaacag atagtatgag
    32881 aatggaagta tcttctccca aactagcgat tggagttaga ggtaagcgag aagtttctga
    32941 agcggattgc tatcgacatc atattttatt aaaattattg tttgcaatga tgtttggttg
    33001 gacttcgaat cgttttcaaa aatgttatga atcaggtaaa attgatgcat ccttatctct
    33061 ggaagttgaa gtaacaagtc gctttcattt tgtcatgttg acaatggata cgaaagagcc
    33121 agttgctttg tctcatcaat ttaggaaggc tattcgtaat tttacaaagg atttagatat
    33181 tacagaggaa catttagata ttatcaaaag agagatgttt ggcgaatttt tcagtagcat
    33241 gaactctctt gaatttattg caacgcaata tgatgctttt gaaaatggtg agacaatttt
    33301 tgatttgccg aaaattttac aggaaattac tttagaggat gtccttgatg ctggacatca
    33361 tttaatagat gatggtgaca tagttgattt tacaatattc ccatcgtagt aacctattat
    33421 aatagacact agaaagaagg gatgacaagt atgagaaaaa aaacaattgg agaggtttta
    33481 cgattagcta gaatcaatca gggattgagt ttagatgaat tgcagaaaaa gacagaaatc
    33541 cagttagata tgttggaagc aatggaagca gacgatttcg atcaacttcc aagtcctttt
    33601 tacacgcgtt ctttcttgaa aaaatatgca tgggctgttg agttagatga ccaaattgtt
    33661 ttggatgctt atgattctgg gagtatgatt acttatgagg aagtagatgt tgatgaagat
    33721 gagttgacag gtcgtagacg ttcaagtaag aaaaagaaga aaaaaacatc atttttacct
    33781 ttattttatt ttatcctttt tgctttatcg attttaattt ttgtgactta ttatgtttgg
    33841 aactatattc aaactcaacc agaggagcct tctctttcta attacagtgt ggttcaatca
    33901 acaagttcaa ctagctctgt tccccactcc tcaagtagta gttcttctag tatagaatca
    33961 gctataagtg tatcaggcga aggaaatcat gtagaaatcg cttataagac aagtaaggaa
    34021 acagttaaat tgcaattggc agtttcagat gttacaagtt gggtcagtgt ttcagaaagc
    34081 gaacttgagg gcggtgtaac cttatcgcca aagaagaaaa gtgcagaagc aacagttgca
    34141 actaaaagtc ctgtaacaat tacgttaggt gttgtaaaag gtgttgattt gacagtagat
    34201 aatcagactg ttgatttatc gaaattaaca gctcagactg gacaaatcac tgtaaccttt
    34261 actaaaaatt aaggaaaaac gaatgaaaaa agaacaaatt cccaatctct taacaatagg
    34321 tcgaattctc tttataccta tttttatctt tattttaacg ataggaaatt cgatagagag
    34381 tcatatagtt gcagctatta tctttgctgt tgccagtatt accgactatt tagatggata
    34441 tttagctcgt aaatggaatg tggtcagtaa ttttggtaaa tttgcagatc ctatggcgga
    34501 taagttacta gttatgtcgg cttttattat gttgattgag ttaggtatgg ctccggcttg
    34561 gattgttgca gtgattatct gtcgtgagtt agctgtgaca ggtttaaggc ttttattggt
    34621 tgaaactggt ggaacaattt tagcagcagc aatgcctgga aaaattaaaa cttttagtca
    34681 gatgtttgct attattttct tgctattaca ttggactttg cttggtcaag ttctacttta
    34741 tgtagcctta tttttcacta tctactctgg ctatgactat ttcaagggta gtgcctatgt
    34801 atttaaaggg acatttggtt cgaaatgaaa tcaataattg atgtaaaaaa tctttctttt
    34861 cgctataaag aaaatcagaa ctactacgat gtgaaggata ttacgtttca cgtgaaacgt
    34921 ggagaatggc tttcgattgt agggcataat ggtagtggta aatcaactac ggttcgatta
    34981 attgatggct tactggaagc agaatccgga gagattgtaa ttgatggcca acgtttgact
    35041 gaggaaaatg tttggaatat acgtcgtcaa atcggtatgg tttttcaaaa tccagacaat
    35101 caatttgttg gagcgactgt tgaagatgat gttgcttttg gtttggaaaa tcagggactt
    35161 tctcgtcaag aaatgaaaaa gagagtggaa gaagctctgg ctttagttgg catgttggac
    35221 tttaaaaaga gagagccagc gcgtctatca ggtggtcaaa agcaacgtgt ggccattgca
    35281 ggtgttgtag ccctaagacc agctatttta atcttagatg aagcaacgag tatgttggat
    35341 cctgaggggc gtagagaact tattgggaca gtaaaaggaa ttcgaaaaga ctatgatatg
    35401 acggtcattt ctattaccca tgatttggaa gaagtcgcca tgagtgatcg cgtattggtc
    35461 atgaaaaaag gggaaattga atcaactagt agtccaaggg agcttttctc tcgaaatgat
    35521 ttagatcaaa ttggattaga cgatcctttt gctaatcaat taaaaaaatc tttgagccag
    35581 aatggctatg atttacctga aaattatttg acagaaagtg agctagagga taagctatgg
    35641 gaattgctct agaaaatgtg aattttacat atcaagaagg tactccctta gcttcagcag
    35701 ctttgtcgga tgtttctttg acgattgaag atggctctta tacagcttta attgggcaca
    35761 caggtagtgg taaatcaact attttacaac tcttaaatgg tttattggtg ccaagtcaag
    35821 ggagtgtgag ggtttttgat accttaatca cctcgacttc taaaaataaa gatattcgtc
    35881 aaattagaaa acaggttggc ttggtatttc agtttgctga aaatcagatt tttgaagaaa
    35941 cggttttgaa ggacgttgct tttggaccgc aaaattttgg agtttctgaa gaagatgctg
    36001 tgaagactgc gcgtgagaaa ctggctctgg ttggaattga tgaatcactt tttgatcgta
    36061 gtccgtttga gctgtcaggg ggacaaatga gacgtgttgc cattgcaggc atacttgcca
    36121 tggagccagc tatattagtc ttagatgagc caacagctgg tctagatcct ctagggagaa
    36181 aagagttgat gaccctgttc aaaaaactcc accagtcagg gatgaccatc gtcttggtaa
    36241 cgcatttgat ggatgatgtt gctgaatatg caaatcaagt ctatgtaatg gaaaagggac
    36301 gtttagtaaa ggggggcaaa ccaagtgatg tctttcaaga cgttgttttt atggaagaag
    36361 ttcagttggg agtacctaaa attacggcct tttgtaaacg attggctgat agaggcgtgt
    36421 catttaaacg attaccgatt aagatagagg agttcaagga gtcgctaaat ggatagtatg
    36481 attttggggc gttatatccc aggggattcg attgttcacc gattggatcc acgtagcaaa
    36541 ttgcttgcta tgatgctact gattttgatt gtgttttggg ctaataaccc cttgacgaat
    36601 ctgattcttt ttatagcgac agggatattt attgccttgt caggagtatc tctttcattt
    36661 tttattcagg gcttgaagtc tatgtttttc ttgattgcct tcacaactat ttttcaacta
    36721 tttttcattt ctaatgggaa tgttttattt gagttttcgt ttgtgagaat cacggattat
    36781 gctttgcaac aagctgggat tattttttgt cgctttgtat tgattatttt cttttcaact
    36841 ttgttaacct taacaaccat gcctttaagt ttggcatcag ctgtcgaagc tttattagca
    36901 cctttaaagc gtgtgaaagt tccagttcat gaaattggat tgatgctgtc tatgagtttg
    36961 cgttttgtcc caaccttgat ggatgatacg actcggatta tgaatgcaca gaaagctcgt
    37021 ggagtggatt ttggagaagg aagcatcgtt caaaaagtaa aggcgatgat tcccattttg
    37081 attcctcttt ttgcgacaag tttaaaacgt gcagattcct tggctatcgc tatggaagcg
    37141 cgtggctatc agggtggaaa aggcagaagt caataccgac aattgaaatg gactctaaag
    37201 gatacgctga ccattcttgt tattctcgta cttggttgtt gtttattttt cttaaaatct
    37261 tagtagcttt caggaattga taaaaagtta ctgtaacagt ttttgatata aaggtaggga
    37321 tatgaaccgt tttaaaaaat caaaatatgt cattattgtt tttgtcactg ttctgcttgt
    37381 gtcagctctc ttagcgacga cttattcaag tacaattgtg acaaaattag gagatggaat
    37441 ctcattggtt gatagagttg tacaaaaacc ttttcagtgg tttgattctg tcaaatcaga
    37501 tttggctcat ttgacacgaa catataatga aaatgaaagt ttgaagaaac agctttacca
    37561 attagaagtt aaatcaaatg aggtggaaag tttaaagaca gaaaatgaac aactgcgcca
    37621 attgcttgat atgaagtcta aattgcaagc cacaaagact ttagcagcag atgttattat
    37681 gcgttctccg gtatcttgga agcaggagtt gaccttagat gcaggtagat caaaaggtgc
    37741 ttctgagaac atgttagcta ttgcaaatgg tggcttgatt gggagtgttt caaaagtaga
    37801 ggagaactct actatagtca accttctgac aaatacggaa aatgctgata agatttctgt
    37861 taaaattcaa catggctcta ctacaattta tggaattatt attggctatg acaaggaaaa
    37921 tgacgttctt aaaattagcc aattaaatag taatagcgat attagtgcgg gagataaggt
    37981 gactactggt ggattaggaa actttaacgt tgctgatatt cctgttggtg aagtggttgc
    38041 cacaacgcat agtacagact atttgacacg agaagtaact gttaaattga gtgcagatac
    38101 tcataatgta gatgtgatag aattagtggg gaattcataa tgagacagtt gaagcgagtt
    38161 ggagtatttt tattgcttcc tttctttgtt ctaattgacg cccatattag ccagcttctg
    38221 ggctcatttt tcccccatgt acatttggct agtcattttc tttttctatt tctcttattt
    38281 gagacgatag aagtatcaga gtatctctac ctagtctatt gttttgttat aggcttggtt
    38341 tatgatgttt actttttcca tctaataggg attacaactc tcttatttat cttattggga
    38401 gccttccttc ataaattgaa tagtgttatt ttgttgaatc gttggacaag aatgctagct
    38461 atgattgtgc tgacattcct gtttgaaatg ggtagttatc ttttggcttt tatggtaggg
    38521 ttgacagtag atagcatgtc gatttttata gtctatagct tggtaccgac gatgatttta
    38581 aattttttat ggattactgt ttttcaattt atttttgaaa aatattatct ataagaacga
    38641 catataaatg taacaaaggc gtaatattta ttaggccttt ttttggtata ctagtattgt
    38701 ctttaaaaga aggagtatct acgtaatatg aagaaaaaaa tcttagcgtc acttttatta
    38761 agtacagtaa tggtttctca agtagctgtt ttaacaactg cgcatgcaga aacgactgat
    38821 gacaaaattg ctgctcaaga taataaaatt agtaacttaa cagcacaaca acaagaagcc
    38881 caaaaacaag ttgaccaaat tcaggagcaa gtatcagcta ttcaagctga gcagtctaac
    38941 ttgcaagctg aaaatgatag attacaagca gaatctaaga aactcgaggg tgagattaca
    39001 gaactttcta aaaacattgt ttctcgtaac caatcgttgg aaaaacaagc tcgtagtgct
    39061 caaacaaatg gagccgtaac tagctatatc aataccattg taaactcaaa atcaattaca
    39121 gaagctattt cacgtgttgc tgcaatgagt gaaatcgtat ctgcaaacaa caaaatgtta
    39181 gaacaacaaa aggcagataa aaaagctatt tctgaaaaac aagtagcaaa taatgatgct
    39241 atcaatactg taattgctaa tcaacaaaaa ttggctgatg atgctcaagc attgactacg
    39301 aaacaggcag aactaaaagc tgctgaatta agtcttgctg ctgagaaagc gacagctgaa
    39361 ggggaaaaag caagtctatt agagcaaaaa gcagcagctg aggcagaggc tcgtgcagct
    39421 gcggtagcag aagcagctta taaagaaaaa cgagctagcc aacaacaatc agtacttgct
    39481 tcagcaaaca ctaacttaac agctcaagtg caagcagtat ctgaatctgc agcagcacct
    39541 gtccgtgcaa aagttcgtcc aacatacagt acaaacgctt caagttatcc aattggagaa
    39601 tgtacatggg gagtaaaaac attggcacct tgggctggag actactgggg taatggagca
    39661 cagtgggcta caagtgcagc agcagcaggt ttccgtacag gttcaacacc tcaagttgga
    39721 gcaattgcat gttggaatga tggtggatat ggtcacgtag cggttgttac agctgttgaa
    39781 tcaacaacac gtatccaagt atcagaatca aattatgcag gtaatcgtac aattggaaat
    39841 caccgtggat ggttcaatcc aacaacaact tctgaaggtt ttgttacata tatttatgca
    39901 gattaattta cagagggact cgaatagagc cctcttttca ggttttaccg tgacaatccc
    39961 tattaaaaat tatatcaaaa tagcttgaaa atattggaaa agtatggtag aatgaaaatt
    40021 gtcgtgtgaa cgataatact cattcttgat gaattgtgaa gcagttgccc ttgggtcgtt
    40081 ttgcgagttg aagtcaagaa gaggaaaaaa acaaaaagga gaaatactca tggcagtaat
    40141 ttcaatgaaa caacttcttg aggctggtgt acactttggt caccaaactc gtcgctggaa
    40201 tcctaagatg gctaagtaca tctttactga acgtaacgga atccacgtta tcgacttgca
    40261 acaaactgta aaatacgctg accaagcata cgacttcatg cgtgatgcag cagctaacga
    40321 tgcagttgta ttgttcgttg gtactaagaa acaagcagct gatgcagttg ctgaagaagc
    40381 agtacgttca ggtcaatact tcatcaacca ccgttggttg ggtggaactc ttacaaactg
    40441 gggaacaatc caaaaacgta tcgctcgttt gaaagaaatt aaacgtatgg aagaagatgg
    40501 aactttcgaa gttcttccta agaaagaagt tgcacttctt aacaaacaac gtgcgcgtct
    40561 tgaaaaattc ttgggtggta tcgaagatat gcctcgtatc ccagatgtga tgtacgtagt
    40621 tgacccacat aaagagcaaa tcgctgttaa agaagctaaa aaattgggaa tcccagttgt
    40681 agcgatggtt gacaccaata ctgatccaga tgatatcgat gtaatcatcc cagctaacga
    40741 tgacgctatc cgtgctgtta aattgatcac agctaaattg gctgacgcta ttatcgaagg
    40801 acatcaaggt gaggatgcag tagcagttga agcagaattt gcagcttcag aaactcaagc
    40861 agattcaatt gaagaaatcg ttgaagttgt agaaggtgac aacgcttaat ttatacaaat
    40921 agtaattacc taggagggcg gggcttagcc cggctctcct attttcaaaa aatataggag
    40981 aattaaaatg gcagaaatta cagctaaact tgtaaaagag ttgcgtgaaa aatctggtgc
    41041 cggtgttatg gacgctaaaa aagcgcttgt agaaacagac ggtgacatcg aaaaagcgat
    41101 tgaattgctt cgtgaaaaag gtatggctaa ggcagctaag aaagctgacc gtgttgctgc
    41161 agaaggtttg actggtgttt atgttaacgg taatgttgca gcagttattg aagtaaacgc
    41221 tgaaactgac ttcgttgcaa aaaacgctca attcgttgaa ttggtaaata ctacagctaa
    41281 agtcattgct gaaggaaaac ctgctaacaa tgaagaagct cttgctttga taatgccttc
    41341 aggtgaaact cttgaagctg catacgtatc tgcaacagca actatcggag agaaaatctc
    41401 attccgtcgc tttgcattga ttgaaaaaac agacgcacaa cactttggag cataccaaca
    41461 taacggtgga cgtatcggtg ttatttcagt tgttgaagat ggagacgaag cacttgctaa
    41521 acaattgtca atgcacatcg cagcgatgaa accaacagtt ctttcttaca aagaattgga
    41581 tgagcaattc gttaaagatg agttggcaca attgaatcac gttatcgacc aagacaacga
    41641 aagccgtgca atggttaata aaccagctct tccacacttg aagtatggat caaaagctca
    41701 attaactgat gatgttattg ctcaagctga agctgacatc aaagctgaat tggctgcaga
    41761 aggcaaacca gaaaaaatct gggacaaaat tattccaggt aaaatggatc gcttcatgct
    41821 tgataacact aaagttgacc aagcttacac acttcttgca caagtttaca tcatggatga
    41881 cagcaagaca gttgaagcat accttgaatc agttaacgct tcggtagttg agtttgctcg
    41941 ctttgaagtt ggtgaaggta tcgagaaagc tgcaaacgac ttcgaagctg aagttgcagc
    42001 tacaatggca gcagccttga ataactaata atagaaagga agcaaattgc ttcctttttt
    42061 gtatagggct tagatttttc ctgaaattgt tttttcccca gtctcactcg attagaataa
    42121 ttaaaacaaa aagccctata ataagggcta agtgcattta ggagactata cttcaaattc
    42181 atagtaagcg cgtcataaca aggtatctat cctaattccc caacttccag tatactagat
    42241 aaaaaataat tatcggagga aaggtattgt actatgataa ttcaactaag tgatttaggt
    42301 caagttcacc ttgtttgtgg caagacagat atgaggtagg gaatagactc attagcctat
    42361 gtagttaaaa cccactttga attggattct ttctccggtc aagtctttct cttttgtggt
    42421 ggacgtaaag accgctttaa agccctttac tgggatggtc aaggattttg gctactatat
    42481 aaacgctttg agaacggaaa actgacttgg ctaagtacag aaaaggatgt caaagctctc
    42541 gcacctgaac aagtagattg gcttatgaag ggcttttcta tcactccaaa aatatagtag
    42601 attgaaacta gaatagtaca cctctgcttc taaaacattg ttagaaatcg atttgattgt
    42661 cctgttctta tttcatttta ctataaatcc atcagaaagt tgtgatttct attgaaatga
    42721 ggactttctt tttacactca tctgctttca aaaagcattc tagtccat
//
LOCUS       DAVHKZ010000015        41124 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000015 DAVHKZ010000000
VERSION     DAVHKZ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.015"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(1..491)
                     /locus_tag="VVO74_000980"
                     /pseudo
     CDS             complement(1..491)
                     /locus_tag="VVO74_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            979..1098
                     /locus_tag="VVO74_000981"
     CDS             979..1098
                     /locus_tag="VVO74_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU5695018.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(1194..2540)
                     /gene="glnA"
                     /locus_tag="VVO74_000982"
     CDS             complement(1194..2540)
                     /gene="glnA"
                     /locus_tag="VVO74_000982"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU5695019.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTVIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2577..2933)
                     /gene="glnR"
                     /locus_tag="VVO74_000983"
     CDS             complement(2577..2933)
                     /gene="glnR"
                     /locus_tag="VVO74_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU5695020.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(3010..3537)
                     /locus_tag="VVO74_000984"
     CDS             complement(3010..3537)
                     /locus_tag="VVO74_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU5695021.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(3673..4869)
                     /locus_tag="VVO74_000985"
     CDS             complement(3673..4869)
                     /locus_tag="VVO74_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU5695022.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(4959..9869)
                     /locus_tag="VVO74_000986"
     CDS             complement(4959..9869)
                     /locus_tag="VVO74_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEU5695023.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFEWGMTVQDTSLPRPLAENIVPG
                     ATVIGSTFPDTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGKWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNKVLPKPTYQPA
                     SDQQKAPKLEVQEEKVAFHRQEHENTEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            10162..11805
                     /locus_tag="VVO74_000987"
     CDS             10162..11805
                     /locus_tag="VVO74_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEU5695024.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKVAEKGHKTEEAINTID
                     EQLTRYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFS
                     DAALKELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRL
                     NKGECSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(12364..13971)
                     /locus_tag="VVO74_000988"
     CDS             complement(12364..13971)
                     /locus_tag="VVO74_000988"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU5695025.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAAAMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(14361..14948)
                     /locus_tag="VVO74_000989"
     CDS             complement(14361..14948)
                     /locus_tag="VVO74_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU5695026.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(15076..15387)
                     /locus_tag="VVO74_000990"
                     /pseudo
     CDS             complement(15076..15387)
                     /locus_tag="VVO74_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(15285..15697)
                     /locus_tag="VVO74_000991"
                     /pseudo
     CDS             complement(15285..15697)
                     /locus_tag="VVO74_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867298.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(15725..16375)
                     /locus_tag="VVO74_000992"
     CDS             complement(15725..16375)
                     /locus_tag="VVO74_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU5695027.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPETLVGFDQSIQTAIR
                     GDLPDYLTILFRSLTHLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASFCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(16365..16928)
                     /locus_tag="VVO74_000993"
     CDS             complement(16365..16928)
                     /locus_tag="VVO74_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU5695028.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(17093..17327)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(17381..17884)
                     /locus_tag="VVO74_000994"
     CDS             complement(17381..17884)
                     /locus_tag="VVO74_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEU5695029.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(18077..18907)
                     /locus_tag="VVO74_000995"
     CDS             complement(18077..18907)
                     /locus_tag="VVO74_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU5695030.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(18892..20574)
                     /locus_tag="VVO74_000996"
     CDS             complement(18892..20574)
                     /locus_tag="VVO74_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695031.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHCPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNLSIS
                     KGQVQLQNELAKETPALQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(20685..20933)
                     /locus_tag="VVO74_000997"
     CDS             complement(20685..20933)
                     /locus_tag="VVO74_000997"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695032.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVR"
     gene            complement(20940..21488)
                     /locus_tag="VVO74_000998"
     CDS             complement(20940..21488)
                     /locus_tag="VVO74_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU5695033.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(21503..22351)
                     /locus_tag="VVO74_000999"
     CDS             complement(21503..22351)
                     /locus_tag="VVO74_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU5695034.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            22539..23888
                     /gene="trkA"
                     /locus_tag="VVO74_001000"
     CDS             22539..23888
                     /gene="trkA"
                     /locus_tag="VVO74_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU5695035.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIETKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            23892..25331
                     /locus_tag="VVO74_001001"
     CDS             23892..25331
                     /locus_tag="VVO74_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU5695036.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(25456..27135)
                     /locus_tag="VVO74_001002"
     CDS             complement(25456..27135)
                     /locus_tag="VVO74_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU5695037.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLILVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEETSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            complement(27205..28617)
                     /gene="lacG"
                     /locus_tag="VVO74_001003"
     CDS             complement(27205..28617)
                     /gene="lacG"
                     /locus_tag="VVO74_001003"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU5695038.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKYNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(28627..28971)
                     /locus_tag="VVO74_001004"
     CDS             complement(28627..28971)
                     /locus_tag="VVO74_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU5695039.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEAYGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(29139..31025)
                     /locus_tag="VVO74_001005"
     CDS             complement(29139..31025)
                     /locus_tag="VVO74_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEU5695040.1"
                     /translation="MVIRVFDKQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRRDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKAFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGQMLWKKTRNYEELIEEYFSALYGENWQSVVEYLEKL
                     SIYSSCDYFNAIGSRQSDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWKNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(31027..32349)
                     /locus_tag="VVO74_001006"
     CDS             complement(31027..32349)
                     /locus_tag="VVO74_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU5695041.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            32517..33740
                     /locus_tag="VVO74_001007"
     CDS             32517..33740
                     /locus_tag="VVO74_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU5695042.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            34390..34560
                     /locus_tag="VVO74_001008"
     CDS             34390..34560
                     /locus_tag="VVO74_001008"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5695043.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            35172..35456
                     /locus_tag="VVO74_001009"
     CDS             35172..35456
                     /locus_tag="VVO74_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695044.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            35449..35697
                     /locus_tag="VVO74_001010"
     CDS             35449..35697
                     /locus_tag="VVO74_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695045.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLHATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            35793..36011
                     /locus_tag="VVO74_001011"
     CDS             35793..36011
                     /locus_tag="VVO74_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695046.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LESFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(36379..38703)
                     /gene="pflB"
                     /locus_tag="VVO74_001012"
     CDS             complement(36379..38703)
                     /gene="pflB"
                     /locus_tag="VVO74_001012"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU5695047.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            39051..40112
                     /gene="dinB"
                     /locus_tag="VVO74_001013"
     CDS             39051..40112
                     /gene="dinB"
                     /locus_tag="VVO74_001013"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU5695048.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILCAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(40259..41104)
                     /locus_tag="VVO74_001014"
     CDS             complement(40259..41104)
                     /locus_tag="VVO74_001014"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU5695049.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
BASE COUNT        12576 a         8737 c         7264 g        12547 t
ORIGIN      
        1 gggagagcaa ttaataatag attaaaatta taatcattga ttgcaggata acttgttcca
       61 gtagatttat tattaacacg attgataaaa ttatctgata ataaataata tttcaaatat
      121 gtttcgttaa gtaaagtatc caaaacaata aatgctgtac tagctatcaa atactcttta
      181 agttctctaa ctacagcaat attttttaga tatggtctaa ctgttgaaaa taagacacta
      241 ttctgcgaaa ctaattttct agcacgggaa ggcgcttgtt caggtgaaag atattgtaga
      301 tttttgtagt tgattatgtt cttttttcta tcaatactag acgtatctat atacctaaag
      361 gatttctctg gcttattttg cccaaaattc caataaattg attttatcct cacccactcc
      421 caagtatcag gaatatcata aggaacatca atttcttgag tgcttccatc agcaaacttc
      481 ccataatgtt tcttatgtgc ttcaagtata taaaaaggcg taaaaatacg cctatagata
      541 atggggttga aataggttta ttgttgatga gattgtagat aattcaattt tttacttcca
      601 atcgaatatt caaagcctcc accttttctg cctgtaattg ttcatcataa aattcaatat
      661 cttcaggatt ttccccttga caacctcggc agaaatattc ttccgctcga tcaggattca
      721 aaaatcgaca agcacaaaca aaacagtcgc catcatcatt tattgagata atatagtaga
      781 ttgaaataag atgtaaacaa atcgattagg aaagttaaat taatttctag aaatttttag
      841 cagatgtagt gtactattct agtctcaatt tactatggct tcaaatatat ctttcgaaaa
      901 aatatttaca gatgtgtaat tttgaagctt gcaaaagtta gtaaacttgt agatttcgat
      961 ttgaagtaac ttgttttctt gcccgatatt gtttttgaaa ttgaattttt ccatagtgac
     1021 tccttgattt tcttctacac gtctgatgat aaatctaatt cgcaaaagag tcaagaggat
     1081 ttttcgaaaa ataaatagcg accgaaatcg ctattttaag ggttataggt atttgatggc
     1141 ttagactgct gtgtgactgt ttacccacag gcaatctttc ttctatatta gtattagtaa
     1201 aggtctaaat aattatcaat ttcccattgt gaaacgaagg ttgcataact tgcccattcg
     1261 attcgtttgg cttcaaggaa gctagtgtag atgtgatctc cgagagcagc tttaaccact
     1321 tcatcttctg tcaaagcttt caaagcgttg tgaagagttg atggaaggtc tgtaatacca
     1381 gcttccttgc gctcttctgc tgtcatgatg tagatatttt cttcgatagg agctggtgct
     1441 tcgattttat tttcaatacc atacaaacca acttccaaaa gaacagccat agcaatgtaa
     1501 gggttcgcca ttggatccac tgaacgcaac tcaagacgag ttcccatacc acgtgaagca
     1561 ggtacgcgca caagtggcga acggttacga ccagcccaag caatgtaaac aggcgcttca
     1621 taacctggaa ccaaacgttt gtatgagtta actgttgggt tcatgatgac agtatagttg
     1681 taagcatgct tgatcaaacc gcctaggaaa tggtaagctg tttctgacaa ctgcattcct
     1741 tttggatcat ttggatcaaa gaaggcgtta tttccttctg catcaaacaa ggacatatta
     1801 cagtgcatac ctgatccagc aataccaaat tttggcttcg ccataaatgt tgcgtaaagt
     1861 ccgtgtttgc gagcaatggt tttaacaaca agtttaaaga tttgaatctt atcacaagca
     1921 cggagaactt catcgtactt aaagtcaatc tcatgctgtc caaccgcaac ctcgtggtga
     1981 ctcgcttcta cttcaaatcc cattttggtc aagacattca caatctcacg acgtgtgttg
     2041 tccgcaaggt cagtaggtgc caaatcaaag tagccaccct tgtcattcac ttcaagtgtt
     2101 gggtccccat tttcatccaa cttaaatagg aagaattctg gctctggacc aaggttgaag
     2161 gatttgaatc caacttcttc catgtgacga agagctcgtt tcaaattacc acgagggtca
     2221 cccgcaaatg gttcaccttc tgttgtataa acatcacaga tcagacctgc aacacttcca
     2281 ttttcatctc cccaagggaa gactgtccat gtatccaagt ccgggtacaa gtacatatcc
     2341 gactcattga tacgtacaaa accttcaata gaagatccat caaacataac cttgttcgac
     2401 aagaccttat ctaactgttc atctgtagca ggaatttcga cgtttttcat ggttcccaaa
     2461 atatctgaga acataagacg aataaaggta acattttttt ccttgacttc acgacgaata
     2521 tctgcagctg tgattggcat aagttttctc cttaatctat gactacttgc ggttgcctaa
     2581 ccgcgaccaa aaggtgactg tactgaagca aaacgcccct gttggaggag ttcattgtga
     2641 agtgcacgac gtacttcagt ctgactaacc gctttcttgg atttcgcttc acgttcagca
     2701 tattttttct taatggcagc gatattataa ccttcagaga tataatcttt gatttcaagc
     2761 agacgatcca tgtcattcaa ggaatacatg cgacgatttc cttcgtttcg atcgggcttg
     2821 atcaactctt gatcttcata ataacgaatc tgacgcgccg atagatcggt caacttcata
     2881 acactgccga taggaaaaac agccatattt cggcgaaatt ctttttcctt catttacaat
     2941 ttccttcttt ctgtctatta tagtctaaaa aaagacaaac gtcaattgat aatgttataa
     3001 aatgtaacat tatttttctt ttttctctaa aaagagacga atacgatcaa tatcgtaatt
     3061 tacgataatt gcgacaaaaa ctcccataaa cgtttctgat acacgcacaa acacgtacga
     3121 aattgtctca ccacttggaa ttgatagggt aatgattaac atagctgcta caccaccaat
     3181 aacccctgct ttgttattca tggctacatt tgtcataatg gttaacatgg tgcagattgg
     3241 aacaactacc aaggtcaccc aaaaggcttc gtggaaaaag gtatttaata agaagaagac
     3301 caaggcatag agtccaccga tactatttcc tagaatacgc gaagtcccaa aatgaacact
     3361 ctcatcaaaa ctctccctca ggctaaaaac ggctgtcaaa gcaccaattt gaagaccttt
     3421 ccagccaaaa aagccaaaaa tcaagagaac tagaaaaaca gcaatacctg ttttaaaggt
     3481 tcgcatacca agtttgaact gggatttatc gaatttatat tttttaaaat aactcataat
     3541 ctcaactttc tatttccatt ttatcataaa tcggtgattt ttatgagtaa tagttgagag
     3601 gaagcgtttt tattttaagc aaaagaaaag aggaactttc atccctctct tctttgattt
     3661 gtttataaaa tcttattttt ctgtcaaggc tgcaagtcct ggaagaacct taccttcaag
     3721 aagttccatt gatgctccac cacccgtact aatccatgag aacttgtctg cacggccaag
     3781 gttaatcgct gcggcagctg agtcaccacc accgatgatt gatttaactc ctggttgttt
     3841 cacgatagcg tccatcacac cgattgtacc agcttggaaa tctgggtttt caaatacacc
     3901 cataggtccg ttccatacaa ctgttttggc accagtcaaa gcttcgtcaa atttggcgat
     3961 agattttgga ccgatgtcaa gaccaaggaa gccttcagaa actgcttcac cttcagtgtc
     4021 acgcacttca gtgtaaccag caaatgcgtt agcttctttt gagtcaactg gcaagatcaa
     4081 tttaccattt gctttttcaa gaagagcttt cgcaacatcc aatttgtctt cttctacaag
     4141 tgagttaccg atttcgatac cttgtgcttt gtagaatgtg taagtcatcc caccaccgat
     4201 aaggacttta tcagcttttt caagcaagtt ttcgataaca ccgatcttgt ctgaaacttt
     4261 tgaaccacca aggatagcca cgaatggacg ttctggagtt tcaactgctt cttggatgta
     4321 ggcaatttcg ttttcaagaa ggaaaccagc aactgctttt tcaacgtttg ctgagatacc
     4381 aacgttagat gcgtgtgcac ggtgagctgt accgaatgca tcgtttacga agataccatc
     4441 tccaagtgat gcccagtatt taccaagttc aggatcgttt ttagattctt tcttgccgtc
     4501 aacatcttcg taacgagtgt tttcaaccaa gagaacttgt ccatcttcaa gagcgttgat
     4561 tgccgcttcc aattcagcac cacgagtgac acctgggaaa acaacatctt gaccaagttt
     4621 tgctgccaag tcagctgcta caggagcaag tgatttacca gctttatcag cttcttcttt
     4681 cacacgtcca aggtgagaga aaagaattgc acgtccacct tgttcgatga tgtacttaat
     4741 agttggaaga gctgctgtga tacggttatc gttagtgatt acgccatctt tcaatggtac
     4801 gttgaagtca acacgaacga ggactttttt acctttcaag tcaacgtctt taacagtaag
     4861 ttttgccatg ttacaaaaac tcctttattt attttattcg aaactattat atcacacttt
     4921 ggaaatataa ggaaagattt cacaagattt ttcgatattt aatctttatc ttctcttttc
     4981 cgtctcaagg tcaaggctaa actagcaaga ccaaggctgg ctaagcctgc tattagggct
     5041 tcattagcat cagctgttcc tgtatttggc aattgtttgc ttgcttcttc tgatttaact
     5101 gctgtatttt gagctggttt ttcctgtgta gctactactg ctggtactgt ttttactttt
     5161 gttccaattt caacaatttc tggaatcgct tcttggatga cttctgttga acgaagacga
     5221 cgctgaccgt tttcatcaac ttcaaagaca tgtcttaaca gtccatctcg tccctgtatg
     5281 atgactcgtt gttccccaac tagcatctca gtattttcat gctcttgacg atgaaaggca
     5341 accttttcct cttgaacttc caatttagga gccttttgtt gatcagaagc cggttgataa
     5401 gtaggttttg gaaggacttt gttttgtggt gctggtttag caggttgtgg tttttcagca
     5461 gattcataaa caaaggcata atgagtaaag tgtggtgctg taaagataac atgactatcc
     5521 gtttgttcaa aagccaattc tactgcctct ttgccttcag gtaagaaaaa tactttctta
     5581 actttcttat ctttttcaat tgggattttc acaatagaag cgtaagagag atcaacatct
     5641 tgaccttttt catccaaacc ttctatttca aagacatgag catcttctcc agcaaagtat
     5701 ttcttctctt cagcacttgc ttgaacacgc tctactttca aacccttgat gacagtcttc
     5761 tctttatttg agaagtgtac ttcaacacct gttttactat cagaaaagac tgctggcttg
     5821 tcttctttca ataaagcaac cagatctttt agactctgtt tcgctgttgc aagctcttct
     5881 ggactcaaat ctactttttc aaccaaggcc ttgtttttct caagaagcgg agctagggca
     5941 gaacctgaag gatggtttgg tttggcagcc aagagttctt gaacctcacc tgttaagcga
     6001 tcaagttctg tcttttcttc cttaaatttc tcttgaccat tcagagcttt atgagcttct
     6061 gtcaatttat taagtcggtc attgacttga tcttgggtgc tagtttcatg gtctttcaac
     6121 acttgttcgg ccgcttcaat tgctttcaag aaagcttctt ttacttctgg tgaagcaaag
     6181 ttatagacca ccttgttctt agcagcttca acttctgcta atttctgttt gaggtactca
     6241 tcgttcaatg ctgcttttgg agataccaaa acatcaaagt tgacttcatg accttggtaa
     6301 cgaagcgtca aggtttgacg accagtcttt tgagcatcgt aaccagaaat ttcaactccc
     6361 tcatcagtaa aggaatgttc ttccatggtg tcattgctat aagccactgc aaagcgtcct
     6421 tcagacaagt ctaagctatc accaactagg taatcttttt tcggttcctg acttacttca
     6481 attcccaaaa tagttttcgg acttgcttcg tcttggccag tgacagtcac tgacaaatta
     6541 gcatttactg gttgtcccaa atattggaga gtaagattct gttctccctt atgatgcgta
     6601 tcaaaacctg atactgatac acctgcgtga gttaggcgaa tgagttcgtc ctcagttcct
     6661 ccttcatact gaactcgaag aacaccacct ctaaggtcca aatcctcccc ttcggcgtag
     6721 cttgttttct taggtcctgt ttctaggctg actgacttga ttcttctgtc atcttttgga
     6781 acggaaactg ctaggacatt actaatttcc ttgcctggca actgggtacg ataataaaga
     6841 agaccagatt gatttgtcaa atccaatggt gcacttgcta ggtctcctcc aacttcgctc
     6901 ttcaaggttg cgagtggagt ttgagaattt ggattatcat aaacggtaat agttgctcca
     6961 gccggtacat ctgcaaagcc aacttgtacc ttgttattgc ctagagaacg ggctgcagcc
     7021 ttggccatcg gaatattgac actctcagta tcaagctttt catacatttt ccagttatag
     7081 atacgaatag ccttccatgg agttccattg tcagaagtga caacattcaa gcgccagtct
     7141 tgagcagtga ttggtttatc aagagtgata tctgtcacgt gtgctttgtt gccacggact
     7201 tccttagcta gcttccactt accatctgca tctttataat aaaggtcaaa gtctttggtg
     7261 ttcatcaagc catcgttaac agactcacca ccagcccctg catgatccat gacccatcta
     7321 acaacggtac gtggcttggt caaacgaata tccacactac cactcaactg agctgaagac
     7381 catttatctg acaagctagt aatggtaccg ttcaacatac cttcaatacc ttctccacct
     7441 tctgtatctg ggaaggtact tccgataaca gtagcccctg gaacgatgtt ttctgctaga
     7501 ggtcttggaa gacttgtgtc ttggacagtc atcccccact caaaggttgt ggttgcagct
     7561 tctgaacgaa ctccattttt accgactgct acaaccttca gttcttgagt tgtaccctga
     7621 gcacttgctg agcggctaac ttttggtaga taaatagttg tagaagatga gccagttagt
     7681 aatttccagc tgtctccatc tttttcataa acttcataga aatctgcatc cttgttgcct
     7741 ttaaattgca caactgcttc cgcttcttgg gcatttttaa gagattgttt cactacagaa
     7801 aagcttgtcg gcgattgtgg ctcttggtga ttgtccgaga tagttaattg tcctaggtta
     7861 aactgataat cttttacagc accttcatgc tcgaaaaata gtttgactgc atagatggtt
     7921 ttacccgcta gtgagctaag atcaaattct tcatttgtcc agttgtcaga aagggttagc
     7981 tctttccatg catctgcatc atcgaatttg tagtctggag ttgtagagaa tgccatataa
     8041 actttagaac cttttcctcc cttgtgggca acacgaagtt tggtcttctc agttacttct
     8101 aacttagtag aataaagtct cacatcctga tctgtcttac cggctacatc accagagaat
     8161 ttaagggaat ttccgccatt ataggcatct gtaaaatcat attctgcacg aagtttttcc
     8221 cctgttgaag tctgccacca gcgccatgtt ggaagaacac ctgatactga acgataattc
     8281 cactcagaat ccttagaaac cttaccatct acgaaccatt ttttaccatg acctgtatta
     8341 aaagaagtag taaaagtatt acctaccgct ggcgtacggt ccgcaactag gttagcaata
     8401 ccataccaat ctttgtcacc tggtttttga ccagtagggt ctccttgata acctgtaaag
     8461 aagatatctt catttttatg ataatcttca ccagtttttc ctaaacttgt aatggtatct
     8521 ggggcaaata aaccaagaga aaggcgcaat ttcccatttt cgtctaaaat gtcattccac
     8581 ttaacctttg tcttgtagga accaccctgt tgcaattcca aacctgcaaa tacatcataa
     8641 ggattacgac caatccagtt ggcagttgca atagtgtaat catttttagc cttatcccag
     8701 ttaaagttag caaagaagtt atctgccgga accttatctc cttctggttg catgaattgg
     8761 tagttgtatt ctcccaaacc atcttgatgg taacgtccat agttataggt catggcatca
     8821 taccaagaat acttgattgg atggtttacc ttagcagcat attccttgct atagagcata
     8881 aactggcgca tcttttctcc aagaggttta accaaatctc cagttgtttc ttggttgatg
     8941 aaatagccat catagccata atacttggcc atgtctacca atttacgggc aattgggaag
     9001 ctaccatctg cgtcttgctt caaagcttca gcaaatcttt cttgatctgc aatactatta
     9061 gaccagttga agaagagtgt accgtataca ggaaccccgt tacggtgacc tgcatcaata
     9121 acgtcaggag ttggtacgag accttcccag aagaccattg aatctagata ttgccaatag
     9181 tcaaaagcat aggccttgaa ctcttctcca ccaacagaag catggtcttt tgctttagaa
     9241 ttggtgtttg ataaggcttg aacttttgct tccttgctag ctttttcatt gactaaatga
     9301 cctgtccgac gtgaagcgag gacaacagat ccgcggttaa tagcatcatc ttcacgagca
     9361 cctggttccc attttaacaa ttcttcccaa gaattaaatt tgatttcctt tggttttaat
     9421 gttttttctg tatttttagg gacatctggc tggacttctt tttcagtctt attagcttct
     9481 gctgctggct tagactcatc cccttggtta gttgcttcgg gctttgcttc tgtttccttg
     9541 tcagacttag gttttgcttc tgcagatggt gtttctgcaa ccacctcacc tgctttttcc
     9601 tctggtttag ctgcgctagc tgcttctgcc ttttctagct tgttttctct agcatgttcc
     9661 ccttcattct gcttatcagc ttcattggtc gaatgctcac tctctcctga aacaagctct
     9721 gtattagctc cgctattttc aggaactgca gtttcttcag ccaaggctgg accagcaaat
     9781 aaaacagcac caatcatcag cgagcaggct cctactgata acttacgaat actgtaacga
     9841 caacgtcttt caaaaaatgg attcttcatt ttctcctcct aaaagattga ttttgttgtt
     9901 ttaaagaaag cgctttatat tctgtagttt tttatcaaac tctagaacca tgataatcac
     9961 atttttatcc taaaacattt ttagacaaaa aacaataact gtttgcacaa atctaaaata
    10021 aggttaaaaa ctcttaaaaa taatacactt atcaattata attttctttt acaaacttga
    10081 cattaacact tgttagattt acttttatcc tttaaaatag aataggagat attccgcgat
    10141 tatttttcgg aggaaaaaga aatgtccatt aattggcagg aaattttatt tcacttttta
    10201 ggtggtctgg ggctattctt atatagcatc aagaccatgg gagacggttt gcaacaagct
    10261 gctggagatc gccttcgttt ttacattgac aaatatacta gtaatccttt ctttggagtt
    10321 ctggttggta ttgggatgac tgctctaatt cagtctagtt ctggtgtaac agttattaca
    10381 gtcggcctgg tcagtgccgg tctcttaacc ttacgtcagg ctatcgggat tgtcatgggt
    10441 gctaatattg ggacaactgt cacatccttt ctcatcggtt ttaaattagg taactatgcc
    10501 ctacctatgc tctttatcgg tgccgtctgt ctctttttta cgaaaaatcg gacagtcaat
    10561 aatatcggac gcatcctctt tggtgtcggt ggtatctttt ttgccctcaa tctcatgagc
    10621 ggcgcaatgg ctccactcaa ggatttacag gtctttaagg actatatgat tgagctaagt
    10681 aagaatcctg ttttgggtgt ctttgtcggt accggcttga ccttgctaat tcaagcttct
    10741 tcggctacca ttgggatttt acaaaacctc tacgccggca atctaattga cctacaggga
    10801 gctttgccag ttctatttgg tgacaatatc gggacaacca ttacagccat cattgcctct
    10861 ttaggggcta atattgcagc taaacgggta gcaggagctc atgttgcctt caacgttatc
    10921 ggaacagtcg tctgcgttat ttttctagtt ccttttactg tcctgattca ttggtttgaa
    10981 gctacgctaa atctagcacc ggaaatgacc atcgcctttg ctcacggaac ctttaatatt
    11041 accaacacca ttgtccaatt tccatttatc ggagctctgg cttactttgt aaccaagatt
    11101 attcctggag aggacgaggt tgtcaaatac gaacccttat atcttgatga acatttcatc
    11161 aaacaagccc catctatcgc tctaggaaat gctaaaaaag agctcttgca cttaggaaac
    11221 tacgctgcta aagcctttga cctttcctat aagtacatca ttgacttgga tgaaaaagtt
    11281 gctgaaaaag ttgctgaaaa agggcataaa accgaagaag caattaacac catcgatgag
    11341 caattaacac gttatctcat tgccctttca agcgaagctc tcagccaaaa agaaagtgaa
    11401 gtgctcacca atatccttga ttcctcccgt gatttggaac ggattggaga ccacacggag
    11461 gctctactca atctgactga ctatcttcaa cggaaaaatg ttgaattttc tgatgccgcc
    11521 ttgaaagaat tagaggaagt ttaccgccaa actagtgact ttatcaaaga tgctctggat
    11581 agtgtggaaa acaatgatat tgaaaaagca cgcagtcttg tagaacgtca tgaagcaatc
    11641 aataagatag aacgtgttct cagaaaaacc cacatcaaac gcctcaacaa aggcgaatgt
    11701 tcaacacaag ctggggtcaa ctttatcgac atcatctcac actacactcg tgtatcagac
    11761 cacgctatga accttgctga aaaggttttt gcagaacaaa tctaagaacc aagaagctat
    11821 ccatcataat tggatggctt cttacttttt cctaagcaag actaggctga atgaaactga
    11881 aagagtattc tgcagatata tagtatattg aaactagaat agtacacctc tatttctaaa
    11941 acattgttag aaatcgattt gactgtcctg atcgatttgt cctgttatta tttcatttta
    12001 ctatagtgga ttaaattaaa aaagtataat gtattgaatc tataacagta catcttgact
    12061 gctaaaatat ttctataaat taatttgact ttccttatag agatgttcac atcttatttc
    12121 aattcatgat acaatccagt tcctaaaact ttgctagaaa ttaatttggc tttccgaatt
    12181 aatttgttca gattttattt catttcaata tactgataaa tccattcact agcacagggc
    12241 aagagggagt cgctattgat ttcaacggta gcaggtacat acagaggact cctacctcag
    12301 atatactgca atatcatcgt atgcaaaaaa cctctgagat ttttctcaaa ggttctgatt
    12361 ttgctaattg ctgttctcaa ccgctgcagt aacaaaggca gtgtagagtt cttctggtcg
    12421 gtttggacgg cttgacagtt cagggtgata ctgacaagct acaaagaatt tattttcagg
    12481 aatttccacg atttctacca aacgattgtc tggagaaact cctgaaaaga caaaacctgc
    12541 tgcctcaaac tgctcacgga aggcattatt aaactcataa cggtgacggt gacggcgttg
    12601 caccacttct tgattgtgat aagcagcagc agccttagag ccacgtttca acttagacgg
    12661 ataaagtccc aaacgaaggg ttccacccat atcctcaata tcaatctgat cacgcatgat
    12721 atcaatgata gggtattttg tttctggtgc aagctctgca gaattggcac cttcaagacc
    12781 taaaacgtga cgagcaaact cgatacatgt caactgcatt cccaagcaga ctcccaacat
    12841 tggaacatca ttttcacgcg catagcggat ggcttggatt ttcccttctg taccacgttg
    12901 accaaaacca cctggtacga tgatcccgtc cgcatcagac aagagttctg ctacattctc
    12961 tgctgtcaca tcattggcat tgacccaatt gattttaact tctgcatcat tgacatagcc
    13021 agagtgtttc aaggcttcga ccactgagat ataggcatct tgcaactcca catacttacc
    13081 aacaagggaa atcttaactt gtttcttgag gttcatgacc ttgtccacca tggctgacca
    13141 ttctgtcata gccgctgctg gtgcgtctaa tttcaaatga tcacaaacaa tttggtccat
    13201 cccttgtgcc tgcaagttca gtggaatttg gtaaaggtgt tcaacatcca acgattcgat
    13261 aacggcttct ggtgccacat cacagaactg ggccagttta tttttaattc cttgaccagc
    13321 tggctcttct gtacgaataa ccaacatatt tggttggatt cccaagccac gcaattcttt
    13381 gacagagtgt tgggttggtt tggttttcat ttcaccagca gccttgaggt aaggaagcaa
    13441 ggttgtatgg atatacatga cattatccgc acccacatct gccttcatct gacgaagagc
    13501 ctctaggaat ggcaaggact cgatatctcc tactgttcca ccaacctctg tgataatgac
    13561 atcagagtcg gtcgttagag cggcacgctt gattttttct ttcaaagcat ctgtgatatg
    13621 aggaatgact tgaacagttg ccccaaggta ttctccacgg cgttctttac gaagaacttc
    13681 actgtaaatt ttcccagttg tcacgttgga atatttgttg agattgatat cgatgaaacg
    13741 ttcatagtga cccaagtcca aatctgtctc agctccgtca tctgtcacaa aaacttcccc
    13801 gtgctggtaa ggactcatgg ttcccggatc aatattgata taagggtcaa acttttgaat
    13861 ggttactttg agaccacgat ttttcaagag acggcctaga ctcgctgcca caatcccttt
    13921 cccaatagac gataccacac caccagttac aaaaatatat ttcgtagaca tagattcctc
    13981 tttctaaaat gctcaaggtc ttgttaacta cgaggggata tagaaaacaa gaccctacta
    14041 ataagaataa tctgggacga ctgcaccaga ttcacaacta atactcttcg aaaatctctt
    14101 caaaccgcgt caacgtcgcc ttgccgtaga tatgtgttcc tgactttgtc agtcttatct
    14161 acaacctcaa aacagtgttt tgagcagcct acggctagtt tcctagcttg ctctttgatt
    14221 ttcattgagt ataaaataca agaagataac ttcttgaaaa aacaaaaata gctccctaag
    14281 aactagggag ccccgacctc taaaagaggt gcccaaacaa tatgatacct aaaaatagga
    14341 taattgtcaa tagctaactc ttattcctcg ctggtttcag cgtcgtcatc tgaaaactcg
    14401 tcgtcgtctt cgttgagatc cacatcttct cccaagtcat ctggagcgat ttcgttgatt
    14461 tctgcatcat aagcttccac ttcatttttt tcatcatctg gattttcatc atcgtatgaa
    14521 agagctggat ctgcttcgta tgcatcttcg tcttctggat catctgcatt gtagtcaatg
    14581 gcatctgaat caccatccat aaaggcattg acacgttttt tcttagcttt tggtgctact
    14641 tcatcgtcgt cattttcttc aagagcgatg atttcttcgt cgatttcgtc cacaccatac
    14701 catgaacgaa gaccccattt gttgtcccca agtgagatga agctaccgtc aaagttcaac
    14761 tctgtgtaga acagaggcaa agcttcgcgg atatcgctgt ttgatgttcc aaggtagttt
    14821 tgaatttcgt ttacaagatc gctaaaatgc atctcatgat cgcgaccacg aagttctaat
    14881 atagcacgcg ctacctcaat catagatagt tcactttttt cttgcccagc aaatacttct
    14941 aattccaaag cgtttctcct catttatact actatcgcca gagcgaacag actctgacct
    15001 cattttatca tttactcttt attttacgat aattttgcgg aatagtcaaa ggttaagggg
    15061 gagaaagtgg caggattaga ctaattccaa tataaaactc cttccttttt ctgttgctcc
    15121 attttccaca aatccaagcg acttgaaaca cctcctagaa gcatgattgt aggtgtagat
    15181 ttccttgact ctcaattctt tccatccttt tactcgagcc aattcaatca aagcacttag
    15241 aatctttttt ccaagtcctc gatgttggta agcggaattc ccaatcacaa tggggagatt
    15301 atcctgagat agtgtaatat ccccaattgg aaaccattct cccttctcct tgacttcaat
    15361 ccaaaaaagc tcaccatgcc gatccaaaga ggtaagatat gattttttaa atcaaaaaca
    15421 gagtaaatct ttcctcgcaa gcttgcgcat agagatgata tagttcatca ccaccatctc
    15481 tatcccactc agcagaaatc gtatcccgac ctgccaataa agcctgataa gccctgtgat
    15541 gcccatctgt aatcagcaaa caatctccaa aggcaagaat actgattgga tcgacttggt
    15601 ttgtttctgc cgactggtaa agcatctgaa tatcttgcaa cttcttttct gataaatata
    15661 gttgagtcgg atgaagatct actatattga ctttcatttc tttctcctaa agggaattcg
    15721 atactcactt ctgtttgcct ttaaatcgcc attggaagcg gagcttgtca tagaagggaa
    15781 actcgataaa caagactccc aaacccacac agaaactggc aagaacatct gatgggtagt
    15841 gaactcccag atagactctt gataccagca cactgactag gtagaggcca aggacgattt
    15901 gtacgatttt tctccagacc tgatctttaa tccgctgact aagaataaca atcaaagtcc
    15961 ctaccatcag cgttacagct agagaatgcc cacttgggaa ggaaaatccc ttctcctcca
    16021 ccagatgtaa gatagctggt cgtgggcgct ggtagatatt tttaaaggtc acgattaaaa
    16081 gacctgccaa agccagattt cccagcatga agaaactttc tatcttccat cgcttacgat
    16141 aaaagacaaa agctataatg acaacccaag tgataatcac tggaatatca atcagatgtg
    16201 tgagggatcg aaaaagaata gtcaaataat ctggtaagtc tcctcgaatg gcagtctgaa
    16261 tcgattggtc aaaaccgacc agcgtttcag ggtaaaattt gaccatatag ccaagaataa
    16321 cgaaaagtaa aagggcaaaa ctgcccttca ttaaaaatgt ttgtttatct ttcatagtgt
    16381 tttaaggttg gtttcaaaag gacgtacaac aaccagaatg aaacggaaaa gattacaccc
    16441 tcaatcaagt taaaaggtaa taccatggtc attaggtagt tggaaagtcc caaaattttt
    16501 ccaatatcaa agttagcaaa cttagcgtac aaaggaacag cataaacata gttgagaacc
    16561 aacatggcca aggttaaacc aacagttcca gctagagagc ctagtaggaa acgaagggtt
    16621 gtccgttcct ttttccaaat caaagcaaat acgatgacaa aaactcccaa agctacgata
    16681 ttcatcggca aaccaatgta agtattcact ccttggctgt taagaagcaa tttcaatagt
    16741 gagcgaagca agagcactcc tagagcagca ggcaaatcca tgaccaccag acccacaagg
    16801 actggcaaga tactaaattc gatcttgagg aaagatgccg ctggtaaaag cggaaagtca
    16861 aagtacatca gcacaaatga gatggctgat agaattgcaa tggtcgaaag tcgacgtgtg
    16921 tttgtcataa caggttcctc caattttcta taaaatcaga agaagttgga aaggattcct
    16981 ctatctattc tcacttttta tatcccaaaa gttccctctt actctattaa agaaaaacaa
    17041 agcaagtggt tacaatccgg ctataaatct atcaaaacag acaaagctat tctttcgtct
    17101 tctcccatcc agactatact gtcggttgtg gaatctcacc acatcagctt gcgctcgcgg
    17161 acttctttaa agagaaggaa atagagattt ttcttttaga ctaggcgaca agctgtaggc
    17221 ataacttctg gttaggcaaa gcttgtcaac aaagtataaa aggaaaagat catttcctag
    17281 ttaaagtcac cgccggtcgg gaatcacacc ctgccctgaa gactctttta tcataacaaa
    17341 aaacgcttgc aagcgcaagc attttgttca ttttcatttt ttatttcaat ttatccactt
    17401 cataggtatg gacgagctca agacctgcaa agttctgctg gcgaagagcc tcatagacaa
    17461 tcatgcagac ggtattagac acattgagac tgcggacatg ttcatcattc atgggaatac
    17521 ggagagcctt ctcaggatgt tctcgcataa aatcttcagg taagcccttg tcttcacgtc
    17581 caaagagaaa ataatggtcc tcgtcagtcg ataaatccac ctcagaatag actttttccg
    17641 cgaatttcga aatcagatag agttttccct tcatctgaga tatgaaatct tccaaactct
    17701 cgtaaaaata aatctctagc ttatcccagt aatccaatcc agcccgcttc atcttgcggt
    17761 catcaatagg aaagcccata ggcttgatga tgtggagggg agaattggtc gcagcgcaag
    17821 tacgcgcgat attgcccgta ttttgtggaa tttgaggttc aaataataca atgtgatttg
    17881 tcatgacttg cttcctttca ccattgcaaa aaaatagcca cactgcccgg agtcaagctc
    17941 agcaaacagc gtggttaagg catcgttaac ttacctcaca acaggtttga agtaaatcag
    18001 cgaaactact ttcttagtat aacactttca gaatcattgt caatagaaat gacttgattt
    18061 tttcaatttt ttcaagctat ttccaagggt tgtaaaatcg tccctgattc tgcaagataa
    18121 gtagtaaact aactactaaa aacaaggttg ccaagagcaa ggtaatatag tctccttttt
    18181 tcaaggcctg ataactatac catgtgcgtt ttttctcttt cccaaagcgg cgaagctcca
    18241 tggcagtcgc aatggtatca atgcgttcta gcgagctaaa aatcaagggc gtaataatga
    18301 gcagattgcc tttgattcgt tgcataagag aagctttctt ggataattcc atcccacgcg
    18361 cctcctgaga catcttgata gtaaagaatt cttcctgcaa atctggaata tagcgcaagg
    18421 tcaggctgac agaataagca atcttatagg gcacaccaat ttgatttaaa ctggaagcaa
    18481 actgactagg atgggttgtc atcaaaaaga taatagccag aggaatggtg caaagatact
    18541 taatggccaa atttagcaga taaaagagct cctggctggt tagagtgtag acaccgattc
    18601 cctgccaaat cacacttctc tctccataaa gtccaacccc atactcggga gaaaagagat
    18661 agaccatcaa aacgtttaaa acggcaaata ccgtcgcaaa aacggctaca aaggaaacat
    18721 ctttaaagcg aatttctgat aaatagagga gaaagactga aaagatggca atcagcaaga
    18781 gcattctggt atcatagcta atcatggccg ccaatgatac cagaatgaaa aagagaagtt
    18841 tcccagctcc tgacaagcga tgaatcacag tatctctatg ctggtaaccg attaatttag
    18901 cttgcatccc tctctccttt ctttgtaaaa tgccgttaaa tccagtggat ccacatctag
    18961 tttcttagcc aagttaaaga tggaggtttc ttttagattg gcttttacta acagctcagg
    19021 atcgctcaac agactggctg gaacagtatc ggcaatcaat tctccatcca ccatgacaag
    19081 gacccggtct gaataatcca gcatcaattg catatcatgg gtaatcatga caatggtatg
    19141 ccctttttga tgtaactctt cgagaaattc cataatctca gtatagttct tctgatcttg
    19201 acctgcagtc ggttcatcta ggagaataat ttcagctcct aagaccaaaa ttgaagcaat
    19261 ggtgacacgt tttttctgac caaatgacag ggcagaaata ggccaattac ggaattcata
    19321 aagtccacag attttcaagg tttcatatac tctcgtttca atttccttct catccacacc
    19381 tcgcaaacgg agccctagag ccacctcatc aaaaatcata ttggttgaaa tcatttgatt
    19441 aggattttgt agcacatatc ctactcgttc cgcccgctct gcaacagaat cgccttttat
    19501 atcctgtttt tcccaaagat agcgtccttc cgtctgaata aagctactta tagccttggc
    19561 tagagttgat ttccctgctc cattttttcc gacaatagca atcttttcac cctttttaat
    19621 atctaaatgt agggatttta aaatcggtct atcatcataa gaaaaagata cttcctctag
    19681 tctaaagagt gactgcaatg ctggggtttc ttttgccagt tcattctgca actgaacctg
    19741 accttttgag atagacaagt tatccagatt cgctaattgt tcttccttga ctaaatccac
    19801 acccaattga cggagagtgg tgagataaag gggttcgcga attccatttt gggtcaacaa
    19861 atcagtcgcc agtaactggt cagggctccc attaaaaagg atacgaccat cgtttatcaa
    19921 gacaatccga tccacagggc aatgcagaac atcctccaaa cggtgctcga taataagggt
    19981 cgtcgtcccc tcctccttat gaatctggtc aatcaattcg ataatatcct gacctgactt
    20041 gggatcaaga ttggcgagtg gctcatcaaa caagagaatc ggactttcat caatcaagac
    20101 accagccaga ctgactcgct gcttttgtcc acctgacaaa tcctgagggc gctgatccag
    20161 taaaggaaga aggtccagct tttcagccca tttataaaca cgacctttca tctcatctag
    20221 ggctgtcaca tcattttcca gagcaaacgc caaatcttct gccacagaca agccaataaa
    20281 ctgcccatct gtatcctgca aaactgtgct aaccagatga gacttatcat agatgctcat
    20341 atcaaaggct gtttgaccct ttatcaaaaa ttctccatat gtctgaccct tgtaaatatt
    20401 gggaataatc ccattcaaac actgacccaa ggtagattta cctgatccag atggtccaac
    20461 aattaagact ttctctccct tgtaaatggt caagtctatc ccttgcaagg tcggttcttg
    20521 ttgtgtttca taccggaaag agaaatcctt ccactcaatt atagcttctt tcatcttact
    20581 ctcttcattc gcttcttaga cttctatttt atcataaatc aagcccttct tgcagtctct
    20641 cctattaaaa tcttagcgcc aaaaagattc ctatcctagc ttacttacct aactaatcta
    20701 taaacatcga aaaagactag ttgcccagcc ttccccatca ttttatactc ttcgaaaatc
    20761 tcttcaaacc acgtcagctt cgccttgccg taggtatggt tactgacttc gtcagtttca
    20821 tctacaacct caaaaccatg ttttgagctg acttcgtcag ttctatccac aatttcaaaa
    20881 cactgttttg agcaacctgc ggctaacttc ctagtttgct ctttgatttt cattgagtat
    20941 tagtcctttt tcaaacttcc tgcacgagtt tgggttcctg cataggcaag taagagaaga
    21001 gttcctgcaa tagctacaga tacaccattg gcaattcccg caacaatccc ttgtgcaaat
    21061 actttttctg ccgcttcttg ataaatcaca acatctccaa gtggtgccaa gacaccccaa
    21121 acaagggcat ttgcaagtag ttgaatgagg ttaaaaataa gaatatcttt ccagtcaaaa
    21181 acaccattga tcacgcgaac gtactttcta aaaagtccca caactaaacc aaagagtccg
    21241 ctagcgataa tccaagtcca ccatagacca taaccagcaa gagagtcctt gattgcatga
    21301 ccaatcaacc cgacaagcaa accgataatc ggtccaaaaa taatagaaag tagcgcttgt
    21361 accgcatact gaagctggat gcttgtattt ggaacagggg ttggaatgtt gatcatcccg
    21421 atgacgacaa agagggcagc gccaattccg acagcaacaa cttgtttaat tgtaaattta
    21481 atttccatac tattctccta ttttatcctt ctattttctt tatttcaatg gtccaagatg
    21541 aaccgacacc tacattatag gccttggcaa aggaaccttg gttgatagcc aaacctaaac
    21601 gatagagaga gttgatgtaa aggatgggtt gcccaattct cacatctgca aatgatttgc
    21661 catagacaac ctgattttga tagaccagca tatcagcatg atagatggtc acttcaaaac
    21721 gatcaccaaa ttctggttcc agcttgtaaa attcttcccg tgtgatagag gtccaaagcg
    21781 aaccgaaacg cacatccaga atatcaatgg ctcccttcac cagatgatct tctatgatgg
    21841 tcgctacgac tggaagctct acaatctgtt ccacactgag ctctggccct acttcctcaa
    21901 aagtaatgtg accactggcc agtttagcac cagtataggc atagacatca cgaccgtgga
    21961 aggtataaga atgctctgtg ttttgacgcc tattggccac ctcagaaatc tcacgaatgg
    22021 ctacaatgcc aacgtgtttc ttgataaagg aaagcgtccc attatctggc gtgacaatgt
    22081 attgattttt tgcagtcttg gcaactacac tcttacgttt cgaaccgaca cctggatcga
    22141 caaccgatac aaacgtcgtt ccctcaggcc agtaatccac cgtctgaaag agacgatagc
    22201 tcccctcaaa aatattataa ggcgtgatat cgtgcgtcaa gtgatggatt tttaaggttg
    22261 gagactcttc taaagccact ccaatcatag ccgataccgc accatcaacc agaccaaagt
    22321 ctgattgtaa taccagtaaa ttattattca ttttatctcc ttgtatatcc tttatcatac
    22381 catatttcag agaaagtcgc taatagctat ttcaattggt tagggtatag ttttacctta
    22441 tagcgaattt tcactaaaag ctcttgttat tagctagtag gtgcattttt tcttgaaaaa
    22501 gggtatgata gttacatcat gaaaaagtag gttttattat gaaaattatc cttgtcggag
    22561 ggggaaaagt tggttttgcc ctctgtcgct ccttggttgc agaaaagcat gatgttttgc
    22621 tgattgagca agacgaagct gttctcaatc atattgtcag tcgctttgat atcattggta
    22681 tccttggtaa cggggccgat tttgccattc ttgagcaagc cagcgtccaa gattgtgata
    22741 tctttatcgc cctgactgag cacgatgaag tcaacatgat tgcagcagtt ctagccaaga
    22801 aaatgggagc taaagaaact atcgttcggg tgcggaaccc tgaatattct aactcttatt
    22861 tcaaggaaaa gaatattctc ggtttttctc ttatcgttaa tcctgagctc ttggctgccc
    22921 gcgctatcgc gaatatcatt gacttcccca acgccctgtc tgtcgaacgc tttgctggtg
    22981 gacgcgttag cctcatggaa tttgtcgtca agtccaccag cggtctttgc caaatgccca
    23041 tttctgattt tcgtaaaaaa tttggtaatg tcattgtctg tgcgatagag agggatcatc
    23101 aaattatcat tccaagcggt gacatgactg tacaggataa agatagaatc tttgtcactg
    23161 gtaaccgtgt cgatatgata ctcttccata attattttaa atcacgcgcc gtgaagagcc
    23221 ttctcatcgt tggagctggt agaattgcct attatctatt aggtatcctc aaagatagtc
    23281 gtatcgaaac caaggttatt gaaatcaatc ctgaaatcgc tagcttcttt agcgagaaat
    23341 tcccaaatct ctacatcgtt caaggagatg gaaccgcaaa agatatcctg ctggaagaaa
    23401 gtgctcaaca ctatgatgcc gttgcgactc taacaggagt cgatgaggaa aatctgatta
    23461 catctatgtt ccttgacagg gtaggtgtac agaaaaatat tactaaggtc aatcgtacca
    23521 gtctcctcga gattatcaat gcgcctgatt tttcaagtat catcacacct aaaagcatcg
    23581 ctgtagatac gattatgcac tttattcgtg gtcgagttaa tgcccagtat tcagaccttc
    23641 aagccatgca ccatctagcc aatggccaaa tcgaaaccct gcaattccat atcaaggaag
    23701 ccaataaaat gactgccaaa cctctttctc aactgaaatt gaaaaaaggg gttcttattg
    23761 cagccattat tcgaaagggc aagactattt tcccaactgg ggaggatatg ttggaagttg
    23821 gagacaagct cctagtaaca accttgttgc caaacatcac caagatttat gacttgattg
    23881 cgaggtaaga aatgaataaa agtatgattc gttacctcct ttcaaagtta cttttgattg
    23941 aagctgttct cctcttggtt cctgtggcta tcgctgtcta ttaccgtgaa tcgagccaag
    24001 tctttacagc cctcttttcg accataggga ttctcgtatt gttaggcggt tcagggagtt
    24061 tacagaagcc aaaaaatcaa cggatttatg ccaaggaggg agtcttgatc gttgccctct
    24121 gttggatcct ttggtctttc tttggtggtc tcccctttgt cttttctggg caaatcccta
    24181 gcgttattga tgcctttttt gaaattagtt ctgggtttac aactactgga gcaagtattt
    24241 tgaacgacgt ttcggttctc agccgttccc tcctcttctg gcgaagtttt acccacttga
    24301 ttggagggat gggagtgctt gtttttgcac ttgctattat ggacaatgcc aaaaatagcc
    24361 acctagaggt gatgaaggct gaggttccag gtcctgtttt tggcaaggtt gtatccaaac
    24421 taaaaaacac tgcccagatt ctctatctcc tttatctagc tctcttctcc ctctttgtca
    24481 tcatctatta tctagctggt atgcctctct acgatagttt tgtcattgct atggggacag
    24541 cgggaactgg aggctttacc gtctataacg acggaattgc ccactatggc agctcactga
    24601 ttacctatct ggtcagtatc ggagttctgg tttttggggt aaatttcaac ctctactact
    24661 acctcatgct ccgtcgcatc aaggccttct ttggtgacga agaacttcgg gcttacttgg
    24721 tcattgtact ggtttctaca ggcttgatta gcctcaacac cctctacctc tacccagggt
    24781 tttcaaagag ctttgaaatg accttcttcc aggtttccaa catcattaca acaactggtt
    24841 ttggatatgg agatattacc aactggcccc tcttctccca gtttatcctc cttttcctca
    24901 tggcaatcgg tggctctgct ggatcaactg caggtggact caagattatt cgaggcctca
    24961 tcctttcaaa aattgccaaa aaccaaattt tgtcaatcct atcgccccac cgtgttttga
    25021 ctctccatgt gaatcaaacg gtgattgata aagataccca gcataagatt ctcaagtact
    25081 ttgtcatcta tgctatgatt ttgctagcgc ttatctttat tgtcagccta gatagcaatg
    25141 attttctggt cgtgaccagc gctgtcttta gctgtttcaa taatatcggg cctattctag
    25201 gaaccacttc tagtttctca atctttagtc ccatctcaaa aattctcctc tcctttgcaa
    25261 tgattgcagg gcgcttggag atttacccaa tcctccttct ctttatgaaa agaacttggt
    25321 ctaagagata aaatacaaaa tccctctttt tacaattgtg aaagagggat ttttatatta
    25381 aaaaggggga acgtttttaa atccaagcct gtctgtaagc aaagttctta ctcaaataaa
    25441 agatggaaaa acttactaca cagcttggta atgctccaat acaaattgta aggctttact
    25501 tggattcttt gttaaatgaa tatattccat tcctctggta gcaactatct gaatacctaa
    25561 tctttctgca tccaccttca tctctctata ataactccga acttgtggag ccagaataat
    25621 taaatcataa acacccataa tatcataatg agctccgtac gctcctgaat tcgcaatcac
    25681 tctaacttct gctaattgag cgccctcgtt aattgcattg gctaattgcg cacttgttcc
    25741 agaccctgca caaagaacca gtactttcaa ctccttactt tttatttcat ctaactcacc
    25801 aggcattatt tcacttgtct cctcctctaa aataatatca tttgagcttg caacatcttc
    25861 tttcatcagt aactgtctat catacgctct acagaatggc aaataaatca atatgtcgac
    25921 aactaaaatc aaagataaaa atacaaagga gatagattga aaattcgttc caattaacaa
    25981 tcccaaggga ccaggaaagg cccaaggtaa ctggatataa aatccattca ttccaaagaa
    26041 atcaataaag acctttccta gaaatacatt cactggtgga gtcatcaaaa aaggtacaaa
    26101 aagataggga ttcaaaataa ctggcatacc aaatagaaga ggttcattca ctgcaaataa
    26161 aacaggagta attgtagctt tacctaccga ttttaattgt ttagaccgca taaagaaaat
    26221 caaaataaat ggtacaacaa aggtagcccc cgttcctccg atagcagcga tataatttcc
    26281 gaaattaggc gttaaagaat gataaggaaa ctgcccattt gcaagaagtt gagcattctc
    26341 ttccatattg ctcagttgta aagctgtaac agcaggtaag acaatagatg gtccatgaat
    26401 tccaacaaac caaagcaaag cgcacataaa ccaaatcaac atcatagcag gatatgattc
    26461 tgccccctta aaaataggag tcaatagttg ttgaaatact tgggcaaaag gaacatctaa
    26521 actaaaccga gatacaatat ctaacaaacc actaataagt aaaacaaaag aaaaaggaaa
    26581 aatatctcta aaagcttgtg atatagcccc aggaacttcc ttaggtaaat gaatagtaat
    26641 gtctcgctta atacagaatc ggtaaacatt tacagtaata aaggcactga caaacgaagt
    26701 tatcaatcct tgagatccta aatagtttgt cgacaaactt gtagatcccg ttttctcatc
    26761 aactacaagc gttacagtta atacaagata gccacatatg gccgccaaca ttgcagaagt
    26821 atcatttatt acctttccag gaggcatttt tctattaaca tttccagcca atgactttgc
    26881 aactgtccct gaaacaataa cacccaaaac tcccatggtt agcatataca ctttcctcat
    26941 ccaggcaata gctggactcg gtaactctac tccgaaattt ttaggaatca taataataat
    27001 catcaaaaag cttgaaaaca taattaaagg catagtagca atgaatccat ctttaatagc
    27061 catcatataa ttattagtag aaattttttc aaatttccct tgttgctttt caatggcagc
    27121 gactaactta tccataaaaa ctcctcctgt aaaaaattta agctcatagt taaaatatat
    27181 taaacatcag tcaaatcgct aaccttaatt ccgttttagc ccttttaccc aaagagcact
    27241 tttcttaata tatctcttct gtgtttcata atcaacaaag aaaagaccat atcgcttatt
    27301 gtagccattc gcccaagaaa attgatcttg caaagaccat ataaaatagc cttgaatatt
    27361 gactccccta tctcgagcct ctaaaacttt gtgtaaatgt tgctcaatat aacggattct
    27421 tttactgtca tcaataatat cattctcgcc ctctggctta acctctttaa gggctgtacc
    27481 attttcagtt aaataaatga ccggatgttg aggatattct tctttgatac gaagcaacat
    27541 atcaaataac ccttgaggat aaatattcca atcccaatct gttgtcggaa taccaggctt
    27601 ttttacaaat tcacctagag catttaattt aaaagaagac tgtcctttta ttcctgttga
    27661 attaaattct tgtctatttt cacctttgta ttcacgaata aattctgaac gataataatt
    27721 catcccaaac atcgtattaa gaggtgcagc tcttttcata atttctaaat caccatcttc
    27781 aataataaag ctagaattat tagcttccaa tatttgattc aagtgaaaaa gcgtgtcatc
    27841 actgtagtag cccaaaaaag ttccatctaa tagaaattta ttattataaa catcataccg
    27901 tttagctgcc aaaatatttt ctttttgccc atcaatagga tagcctggct ttaaagcatg
    27961 aatacaacct acctttccct caatccctaa ttgatgaaat tcgaggactg caagagcatg
    28021 cgccaacaac atgttatgat ttgcttgaat tgcttcagat aattgaaaat ggtgattcgg
    28081 aggaaactga cctcctatgt attggcctgc agcaagagac atcagttcat tgattgtaaa
    28141 ccaatgcttg acttctgtaa attcttggaa acaaaagcga gcatatcgta tgaaacgatc
    28201 aatattctct ctattcaacc aatcccctgt ttctaacatt ttctgaggcg aatcaaaatg
    28261 atgtaaagaa acaaacggaa tcacattata ttttaagcag gactgaaaga ctctatggta
    28321 ataacgaaca gccaatatat tcggctcccc atctatatca ggaaatatac gaacccaaga
    28381 aatagataaa cgcaaagcct gcaaaccatg ttctgccgcc aaagctatat cctcttcgta
    28441 acgataataa aaatcactag ctggatctgg taagaacgga ctattttctt gcaaataaac
    28501 atcccacata tttattcctt tgccatctac cctagttgca ccctctactt gataagcagc
    28561 ggtagcagct cctaataaaa actccttcgg taaggcttta acctgtaaat tttccatgac
    28621 taatcctcat tgcaaaccaa tatgttcttc aatctttcga attcgttcat attcatcaat
    28681 aaaaaacttt acctgatcat acaatagcat cgttgtcatc aaagtatctt gaccatgaat
    28741 catgataaaa ctcacttcaa aattatctcc atatgcctcc tccgctaata aattagtctg
    28801 ttctcgatgg gcagacacta ttgagtcgtt tgcagactca accaattctc ttgcctgttc
    28861 aaaatatcca tctctcgcaa acgccaaagc atccatcaaa tctgaccttg catctcctgc
    28921 gtaagcgaca attgtaaaac caagcatatt tatttcttct tttgatttca tctttcttcc
    28981 tcctcaatct tgaaccatct tttacacatc attattaaaa tgacttcgct acgatacaaa
    29041 tagaaagtcg accctaaata tcttaaaaat ccttaaattt cataatattt aggatcaatc
    29101 ttctctgaat accttggttc attttctaga cttatgattt ataagtggaa accagcgtaa
    29161 ttttttgcta cttcaattac acgataaaca tccaaattag attggaatag cagttcgtgc
    29221 ccacggatat aattcaacac atttttccac tcatcttgag cttgccttgt ttttccggtt
    29281 gcttgaagat ataaagcctt cgccatcttg acaacatatt cacgatgata actgagctgt
    29341 ttccattcat ccttttgact atttaataac ttagaaatat tttcctcaat aattggtaaa
    29401 aaattatcag ctagattgta agctatataa taatgattcg ctaaaacatc actttgacgg
    29461 ctgccaattg cattaaaata atcacaagag gaataaatgg ataatttttc taaatattca
    29521 acaacagact gccaattttc cccatacaaa gcagaaaagt attcttcaat caattcttca
    29581 taatttcttg tcttcttcca gagcatttgc cccatgacat aattaggaaa attatgaggg
    29641 aatccggcac gtaattcttg acacgaaatg tacccgttca aatgtaggtt ggaaagataa
    29701 gatacatctc tgtaaatagt ttgactaatt ttcatatagc ctaaatcgcc ataatgagca
    29761 cgccctaaag gatagtcata tacgaaacta tctcctttaa atgctttttg ccactcaaaa
    29821 agataagata aattttcctc aagagaattc ggaagtataa ttttattacg cagataaggt
    29881 ttaggcgtag gtatggaatt gtcaaaatct acatctgcat aactcatttc aaatgttctt
    29941 gtaatcggtg caaacatcat ggtaaagcgt tcaggattat ctaatttttc tttctgaggt
    30001 gcccataaca actcatgata aagcagaaaa caaatctttg tatctaatcc ctcactcgtt
    30061 aaagccctat ccaattgatt gagaatacga atatactgat ccgaaaccaa ttcttgtcta
    30121 cagttttcgc attcacaaat attattacga gcatccgaca accatacatg taagtagtta
    30181 acatcaggtc ttttcttggc ataatccttg ataatttcta ccatcttatc agctacatct
    30241 ggatttgaaa aatccaggct ggttaaaatc ggagccgtat taaacaattc tcgtttcccg
    30301 tttatttcag cgacataggg tttcttctcc tctgaaatac taagacctga ttcccagcca
    30361 aattttgaag agtaacctaa aacttcacct gtccatccat gaccaacacg atgatgaata
    30421 agacctcttt tttgcaattc tttatccaac ctatcactca attcttgtac taattcattt
    30481 gaaaattgtt ctttatttag atatggatta aattcatgtt cataccaacg tttcaaaaaa
    30541 gagtagggat tttcaaactg gatgaaaaaa ctgttcatcc caatcttagg tagccaatca
    30601 atgaaatcta gtatattttc aaatgaatcc gctccctcta tacatactcc cctatgatag
    30661 taactggctg tttcatctat agatagctgt ttatctaaaa aatcttcaaa tcgtaactct
    30721 ggaacaaagt catgtccgcg ccctggtcta gtatacacaa ccccaaattc atgaaacatt
    30781 cggtaaattc caataagtaa acctacaatt gtattagact caattctccc cttacccttg
    30841 tctaatgaga taagaacatg gtctcttcta tcctctttat tgactaatcc tacaaaaata
    30901 tccgcttcct tctcctcgac aagttctatg tcagtcttaa agacccgatt tatatagtaa
    30961 cttaattcct ctaaggcaaa gctagaataa gtatttttct gcttatcaaa tactctgata
    31021 accatcttat ttccctccaa cagtagcttt ttctttttca agattgcgtt tatctgcaat
    31081 tttgaagaat ggataataaa ttgctacaga aaccaaaatc aaaacaactt gtaatagagc
    31141 tcctcgccaa ctagctcctg tcgcaaggaa gcctcctatg atcggtggca ttgtccacgg
    31201 aaggattaca cctgttgtat agggtactaa tcctacagcc attgatacat aggtaattaa
    31261 ggcattgatt gtaggagtag caataaacgg aatcagcata atcggattta aaactgttgg
    31321 aaacgtaaat agaatagctg tattgatatt aaaaatagac ggtataatag ctagcttacc
    31381 taatgtttta ttcgcacgac tcttactaaa taggaagaga caaatcgcaa gaccaatagt
    31441 cgctccaccg ccaccaataa atacaaataa atctttaaac ggtaatgtaa taatgtgttg
    31501 gagtgtttgt cctgcagcca cagcttcttg gttttctgta gtaaattgta accaaactgg
    31561 gtctacaaaa gcatttaaaa cttgtccccc attaactcca cagaaccaaa agaatgagtt
    31621 tacaataaca catagaatca tacctggaag cgttcctgca attaacttaa gcggtgttcc
    31681 aacaattgca cctaggagtc cgttgagacc tcctgcaact cctgccgctt caagaccttt
    31741 taagaccaga gcccacaaaa caaaagtagt aaagccaggt aaaagagctg aaaatgattt
    31801 acttaccaca tctgggacac cacttggcat ttttatcgta attccgcgct ggataaacat
    31861 acgataaatc tctgctgtaa ccaatccaat agtaatcgcc ataaacaaag aagatgcatt
    31921 cagactagaa aatggtattg cgccgccaaa taactgcttg acctgctccc catttttatc
    31981 ataaaccata ctcgaaaaac gaggtgccat caatacaaaa ctggataagg ctatgatccc
    32041 tgccgacgga ccatctgtac catatccttc cgacaacctg taggcaatac cgaaacaagc
    32101 gaccaaggag ataatcgcta ctgttgactg attcatagtt gtcaagatac ttagcaatcc
    32161 aacactattc agccaatttg taaaagcctc ttgaggccaa ctgattagaa taagaaataa
    32221 agagccgact aaaatcaaag gcattgccat cataaatcct tcacgaatag ctttcaaatg
    32281 ccgttggttg ccaacttttt caccaaacgg agcgactttt gtttctaaaa acgctaaaat
    32341 attgttcatc accggaactc ctttttttat tttttataaa ttaaatatac cactaacaga
    32401 aagcgttgtc aatatatttt ttgttatttt tacaatattt ttttctttgt atagaataat
    32461 aattttaatt gattttttct tatgtttaat ataaaataaa ccaaaggagg aaacaaatga
    32521 ttacaaaaca atcagccttt ttacaaaata gagccactat actggagttt ctatatcgaa
    32581 atccagcaac atcccgtaca gatattgtta atgaaacagg acttactcca gcaacaacga
    32641 ctaacatcat aaaagagcta agcgaacagt ccctcatata cgaaactggt gatgaattta
    32701 gcgagttttc cggatctgga agacgtagaa aaactatttc tatcacagat aatattccgt
    32761 atgttgttgg aggtattgaa ataaacgtcc taggtatctt tctcagtcta tgtgacttac
    32821 aagggaaaac tcttttcgag acagaaattt tgaatgaaga ttatcctatt tcagaaatca
    32881 attccaccat taccaatatg ataaaaacag ctatagagta cgtccctttg gaaacaaaat
    32941 tacttggatt tggcttatca atacctggac attataacaa agactccgga agtatcatta
    33001 caaacaaccc catatgggaa tcttttaatt tattaaatgt aattaaaaga ttcaattttc
    33061 cttttattgt aaaaaataat atcgattgta tggctatagg acaatacctt tttaatccac
    33121 acaatacccc cgataacttt attttcctgc acgctggatt aggtatttac acttcctttt
    33181 tcacaaaaga aaaaatagga gcctctaaaa atccttatat cggagaaatt ggacacacca
    33241 ttgtcgaatt gaatgggcaa tattgtgaat gcggaaaaaa aggttgttta caaacatata
    33301 tttcggatgc ttggttaatc aaacacgccc aattattatt taaaaattcc caactaactg
    33361 tactaaaaag ccttgtaaag actgaaaaag acattcattt agacaccctt ttaacggctt
    33421 ataatttagg cgactccgct ttacgtcaac aaattgataa aggagtcaat ttattagcca
    33481 cttctattgc aaatctcctc ctcatcaatc ctgctgataa aatctatatc aacagtcaat
    33541 tgcttaatta tcaacctttc actcatgaag tcagggataa aatccaagac cagctccact
    33601 tcgttccctt tactcgtaat atagaaattg aaattttacc ttacaacaaa catcgtggaa
    33661 gtataggagc ttgtgcatta gctatcgtcg cttttttcat agaacatagc aatgtattac
    33721 aagatattat ttcaccttaa tatattagaa atctatagac ctgtttaaat caactataac
    33781 ctgtagtaga tatctcgtat ttagacaata tgaaaacaag acgacttcca tataggaaac
    33841 cgccttctct ctatgttgag tgatttatat taaaataact tttcttctag ctgcatttta
    33901 ttattataaa aacattcatc ataaccctga acttaaataa cgatttttat tcaagataca
    33961 tactcctaga ataaacttta tatgaaattc tcatttttgt ttttacaatt ctccttagtt
    34021 aaatcttgtt taatatatgt tttacatata gtatttagcg ccacatagta ctgaactctc
    34081 tccaaaaacg gttattcctc tttgaatagg gcgttatcac aagaaaagca tctccacgtt
    34141 tcaacttcat atggctcaaa aacaatcaat tgatgctaaa acctgtacct agatgtttcg
    34201 gttcataaaa ccatgaaact gtaaaagtgg atgaaattga tagcgatagt caaatcaaga
    34261 ggcatcataa ctctaaaaag tcacaatata taagttcatc ctcggaaaaa tatcattcta
    34321 attgttgaaa tgcctacatg aaaagaaacg tcaaatactc atgaaacaac gaatacaggt
    34381 atcaaaacta tgacaaaaca agtccctaaa tttactaaag acactgctca actttacacc
    34441 tgtaaatggt tgttgtataa taaagttaca aagatgtacg accacactgt tgtaaatcat
    34501 agtgttcgcg aatatattac tgatagcatt tctacaaata caattgaaga gactggatag
    34561 actttaaacg aaatatgtca gtgttttggc attcctagcc ttcatatcat ttaaagaatt
    34621 ctatagacaa aatttttccc aatacagaca ctcgtaacaa ctgcttcatt tttctaccaa
    34681 catatttagg aacaggataa gatacaagag gattaatcca tagatcagtt ctataccaat
    34741 ctaagacaaa taagctaaaa aaacgattga taataagcaa atagattcca aattttctct
    34801 atctgctcat tttaataaac aatactagtg taactatcct tccagtcaga agcttgtcaa
    34861 atcacaccga aaattcttct aaaatttatc tcgttaggca atcaagcaaa aactcgacga
    34921 tagtacaaac attatcatac agaattgact tcctaaatta tatactttag taaggttttc
    34981 gtataagaaa aaagattcat tttacatttc taaacattct tttctaagat gaaaaacaga
    35041 atttttcgat tgtgatttaa agcaacaaga agattttcag tatcatccta tagatacgag
    35101 ctaattaaga aaaactacat tttcgaatat aaactacaat aatataaact aaattttata
    35161 ggaggaagac aatggattgg tacgattata tgatacaggc atccaaacaa tcacaattca
    35221 acgcaagcca ttggtttcgc tatttgcgaa aagttatttt tgaagactat tcttatttaa
    35281 caaaccaaga tgtagaaaag ttgctagact ccaaagaact aacccgtttt caaaaaatta
    35341 gcttgaagta tgcctttcaa gagcatactc caactcataa atatgtgatt tcattaaata
    35401 aacctgctaa gttaaccaat gttcaaaaat tgatggagaa atacaaacat ggataaaatg
    35461 aaaccggtct tccaagccct aaataaggaa ttaattcagg aaaatctgac tttaacaatt
    35521 atctgtgtcg atggttatgt cttagaatat catggtttac atgccacaca agatgttgat
    35581 gctttttatg accaaaatca gaaaatcaat gaaattattg ctcgtgtagg aaaacagttt
    35641 aatcttaaca tccacgaaga gttatggctc aacaatcatg ttgcaaagca aatatgaaca
    35701 aacaacctcc cttaagttta tgcgaatcct tgtactcatt tgagaatctg accgttttag
    35761 tagtccctat tgagtatgtg ttaggaatga agatgatgag tatcagagag caggatttgc
    35821 aagatattgg tgcaattatt aaatacaaaa actttcattc accattcgat acctttaaat
    35881 atttaaaaga catgggattt gatactattg acctctctgt tctattagaa agttttagtt
    35941 atgcttatgg tatggattgg ttagaaaaat tttttaaaga aaatcaagat aaacttcgcg
    36001 aattttatta acagtatcaa acaagatgat tgtcaattag ccagtcgtct tgttttttat
    36061 gatgaaatga aataaaatct gaacaaatcg cttagagaat tccagtcaat ttctagcgct
    36121 gtttgagacg tttcagtgga ctatagtaaa atgaaataag aataggacaa atcgatcagg
    36181 acagtcaaat cgatttctaa gaatgtttta gaaataaagg tgtactattc tagtttcaat
    36241 ctattatatt tcagattcgg tccactattc cttcccaaaa acattgcata ttgcgccgaa
    36301 ggaattgctc atactatccc aagcacaaaa ccctcagtcg tttgaccgag ggttcctttt
    36361 tattattcaa gaacttgatt agctcaatgc atccaaggcg tcatccattg aaagaacttc
    36421 gtggaagaca cgttgtgtca attcagtttt ttgttctgga gtgaggtatt tagtgtttac
    36481 acagtatcca gagatacgta cgataacgtc ttcgcctgac atgatttttt cgtaaacatc
    36541 gttcaagtcc ataacgttca agttaacgtg ttgtccaccg ttttcgaagt aaccatcaag
    36601 gattgttacc aagttatcaa cttgttcatc acgagtctta ccaagagcgc gaggtgatac
    36661 ttgtgtagtc aatgagatac cgtcagctgc ataactaaag tcaaggctag aaagtgagtt
    36721 caagttttgc aaccaaccac ctttagcttt gttagatggg ttagcacctg gtgagaagaa
    36781 ttcaagttta gacaagttca cagaaccatc ttcgttgagg tatacacctt tgtgaactgg
    36841 tgagttacca gtttgtttag agtaagcaac gttagatgtg attgtcaaaa gtgatactgt
    36901 agcttctgcg tctttgtata gtttgtggct acgtagacga gttgtgtaag cttcgatcaa
    36961 ccattctgcc aattcgtttg aacgtgggtc atcttcaccc cagcgtgggt agtcaccgat
    37021 tgtttcgtaa tcgtagatgt agccatcttc gtcacggatt ggtttaactg tagcgtattt
    37081 gatagctgac aatgtatcaa cagtgttagc aaatccacag ataccgaatc ccatgttggc
    37141 acgttgttta gttggcaaga aggccatttg aacagcttcg tagttgtacc tatcagtcat
    37201 gtagtggatg atgttcaagg catctacgta agtgtcagtc aaccagtcaa gagatttttc
    37261 aaagttcgct ttaactgatt cgaattcaag aacttcgtca cggattggtt cgatatcaaa
    37321 tactttgtag tctttgtgaa catcgtcgta accaccattc aaaccagtaa gaagggcttt
    37381 aagaacgttt acacgagcac cgaagtactg gatgttgtgg cgttgttctt cattttctgg
    37441 atcaagtgga gacacacagc atgagataca gctcatttca ccatatccgt ctttagccat
    37501 tgttgttaca ccttcgtatt ggatagaaga gtgtttgtgg ctcatgtgca tacagtagcg
    37561 acggaagttg tatggcaatt tgtcagtcca aagaactgtc aagtttggtt ctggtgagtt
    37621 accgatgttg tcaagagtgt tcaagaaacg gtagtccatc ttagtaacac ggtgacgacc
    37681 gtcgttaccc ataccagcca tagaagttgt gataaaggtt gggtcacctg agtacaattg
    37741 gtcataagct ttggtacgag caaatttaac tgtacgaagt ttcataacga aatcatcaac
    37801 gaattcttgg atttctgatt cagtaaatgt accacgagca aggtcacgtt ctgcaaagat
    37861 gtccaatacg attggtacac gacctagaga tgtagcagca ccgttaatca cacggcagac
    37921 agccatgaaa gcaatgttaa cccattggat tgcttctttc acgttcatcg ctggtttgcg
    37981 aacatcaacc ccgtaaaggt cacccaggcg aacaacttgt tgcaatgctt ggtattgaag
    38041 gtttacttct tcacgaagac ggattgtttc ttcatcgatt tctttgattg cattccagtc
    38101 atttactttt tcttgcatca agtagtctgc accgtaaaga gcaagacgtg cgtaaacacc
    38161 gatgatacgt ccgcgtgagt atgcatctgg aagaccagtt acagtgtgtg cgtgacgagc
    38221 gcgacgaata tttgaagtgt aggcacggaa aataccgtcg ttaactgttg ttacatattt
    38281 agtgaagatt tcgtgaacag ctgggtctgg ttcgtatcca ttttctttca aagtagtttc
    38341 agccatacgg ataccacctt ttggcatgaa gttcaatttg aagagttcat cgttttggat
    38401 accgaagata acttcatttt ctttgtcgat aaatccagca gggatatcag cgatagatgt
    38461 tggacgagtg tccattggga aacgagtttc ttcgtagtgt gctttagttt cttctacaat
    38521 tttcttgatg tgaagtgaac gctctgttgg tcctgcaagg aagctttcgt ctccatcata
    38581 aggtgtgtag ttagcttgta caaatcgtga tacacttgct ttttctttcc aatctacgcc
    38641 tttgaagcct tcccaagctt tgtcaaaaat atcttgtgct tcaacaactg tcttaacaac
    38701 catattaatg tcctcttttt tctagtaaca gtcatctgtt acattcataa gacaagtata
    38761 ccatatagta accgatttca acaagtgaaa attccctatt tttacacttt cttttctaaa
    38821 acagtctata ttttatttca aactgtatta tatttttgaa aaaataaagt ccttttttct
    38881 ttttttcaga aaaaagggta taataaaaga aaataagcag taacactcaa tggaaatcga
    38941 aaagcaaact aggaagctag ccgcagattg ctcaaaacac tgttttgagg ttgcagatag
    39001 agctgacgtg gtttgaagag attttcgaag agtataaaaa ggtgctaggc atgttgattt
    39061 ttcctttgtt aaatgatttg tcaagaaaaa tcatccatat tgacatggat gccttttttg
    39121 ctgcagtgga aatcagggat aatcctaaac tcagaggaaa acctgtcatt attggaagcg
    39181 accctcggca aacaggtgga cggggagtcg tttctacctg tagttatgag gcaagagctt
    39241 ttggtgtcca ttctgccatg agttccaagg aagcttatga acgttgtccc caggctgtct
    39301 ttatctcagg gaattatgag aaatacaagt ctgtgggact ccagattcga gctattttta
    39361 agcgctatac agatttgatt gaacccatga gcattgacga agcctatttg gatgtgacag
    39421 aaaataaact cggtatcaag tcagcggtca aaattgctcg cctcattcaa aaagatatct
    39481 ggcaagaact ccatctaact gcttctgccg gtatttccta taacaagttc ttagctaaaa
    39541 tggcgagtga ttatcaaaaa cctcatggtt tgacagtgat tctacctgaa caggctgagg
    39601 attttctcaa acaaatggat atttccaaat ttcatggagt aggaaaaaag acagtagaac
    39661 gtcttcatca aatgggcgtt tttactggtg ctgatttact tgaagttcct gaggtgaccc
    39721 taatagaccg ttttggtaga ctaggctatg atctgtatcg aaaggctcgt ggcattcaca
    39781 actctccagt caaatccaat cgcatccgta aatcaatcgg caaggagaaa acctacggga
    39841 agattctctg tgctgaggaa gatatcaaaa aagagctgac tcttctatca gaaaaagtcg
    39901 ctctcaatct acatcaacaa gaaaaagctg gaaaaattgt cattttgaaa atccgctacg
    39961 aggacttttc aactcttacc aaacgaaaaa gtattgctca aaaaacacaa gatgctagtc
    40021 agataagcca aatagccctg caactctatg aagaattaag tgagaaagaa agaggtgtcc
    40081 gcctattggg gattaccatg actggatttt aaagctcaat gaaaatcaaa gagcaaacta
    40141 ggaggctagc cgcaggctgc tcaaaacact gttttgaggt tgcagataaa gctgacgcgg
    40201 tttgaagaga ttttctaaga gtataaaacc ttgaagagtt gccccttcaa ggtttttctt
    40261 atacaaataa acggacaaaa ctgtaaagta gcaaaacact accaagcacg atacggtatt
    40321 taccaaaaag ggtgaagtcg tgttttttca catagctggt caagaagcga atagccacca
    40381 tgctgaccgc aaaagctact cccatcgcga ccaagagcaa aaacaattgc ccaaagctca
    40441 agagttctcc ggctttcaca aatttgaaaa tctttaaggc actagctcca aacataacag
    40501 gaatcccaag atagaaggta aattctgtca caactgaacg actggttcca tttaacaaac
    40561 caccgacaat cgttgcacct gaacggctag tccctggtaa aagagcaaga acttggaaga
    40621 gtccgatata gaaagcggtc gtataaggaa gcttgtccaa ctctgttaca cttggctcga
    40681 tagcacgcgc tttattgcgc ttttccaaat agatgaaggc aaccccgtag ataatcaaca
    40741 tgagagcaac tgaaaccatg ttatggaagt gggtatcaaa ccaatcatca aatttaaaga
    40801 caccaagtaa aggtaaagta gcaatcaaga ccttcaacca tagtctccaa gtcttacgaa
    40861 cttcctgttt gtccttagtc ggtttaaaag gattgagctt gttaaaataa atcaccataa
    40921 ctgctaaaat agcaccaagc tgaatcacga cattaaacat ggacataaag gcttcatttt
    40981 gattttggta ttggatgaat tcctctgcta aaatcaagtg acctgtactg gaaatcggca
    41041 accattccgt aattccttca acaatcccga agaagataga ttttaaaatt tcaataagat
    41101 acatagatta ctccctatat tata
//
LOCUS       DAVHKZ010000016        38319 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000016 DAVHKZ010000000
VERSION     DAVHKZ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38319
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.016"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(391..1023)
                     /locus_tag="VVO74_001015"
     CDS             complement(391..1023)
                     /locus_tag="VVO74_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695050.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(1025..1792)
                     /locus_tag="VVO74_001016"
     CDS             complement(1025..1792)
                     /locus_tag="VVO74_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEU5695051.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            complement(1843..3582)
                     /locus_tag="VVO74_001017"
     CDS             complement(1843..3582)
                     /locus_tag="VVO74_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU5695052.1"
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSES
                     FSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDI
                     VNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGG
                     ESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIIS
                     DIQDRLGHGTAVVAQIVGDDNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDG
                     NDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSN
                     QSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPA
                     GSTLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYK
                     LKDQPYNYMFVKKILEETLPVKNGIKVLNIPNVLRYDLNMLQLEYKNEQSWDSFIDNV
                     NLIELEERIQTTIGIKQINTHNIITIAREGYSQNYLPNTSENTYNSLQVSLVGVLLLF
                     ISMVNILWAKKSK"
     gene            complement(3606..5714)
                     /locus_tag="VVO74_001018"
     CDS             complement(3606..5714)
                     /locus_tag="VVO74_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEU5695053.1"
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRS
                     GYSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYIL
                     DPAKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFF
                     VTALLYVIQSLVPIANRYIIDTNFKDDSYSSRMLFTILFIFTVSFSLMYLLRQIYVAS
                     LKYIMDKEISYDFMKHLIYLPYSFYEKRTLGDILFRANSIVYIREILSNNFIAAILDL
                     LMIVVYAVVLFSFSKYMVIFLISLSLALSIVMYPIIKISKNLIDKNIKEKVNVQNITS
                     EVISKNSDIKLTGEEEFWINKWDNFNTKQLIIGRKLDIHLSIVSSITNVLQIILPVLT
                     LIVGVNIKTFEQLTLGQIVAISTVSPYFISPIISLSDNYIQLMLLKGYFLRIEDVFNT
                     KSELIPERVSQDIKFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGETVAIVGESGSG
                     KSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLRENLTF
                     GHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQMILLARCLLSKP
                     SVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKILVMHNGEIVEI
                     GTHRELLELGGIYKQLYSNN"
     gene            complement(5711..6640)
                     /locus_tag="VVO74_001019"
     CDS             complement(5711..6640)
                     /locus_tag="VVO74_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HEU5695054.1"
                     /translation="MLKILNNSVIYLCLIPLLFLLLIIFPNDSLIYYFRLILISLISI
                     TLHELGHFLVGRCLSYKLEMLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKN
                     SDRNLVFYFFGGGGANLIVAILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAI
                     REIVLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVK
                     GEGSAFTIANHEVFDSNIQENIIHEYYKLLHKSSDWIIPQNLSLEEVVFTLSNYIYSK
                     NNKYLEKIKYLKKLVDFRQEEIIDFILNKEEVL"
     gene            complement(6621..7325)
                     /locus_tag="VVO74_001020"
     CDS             complement(6621..7325)
                     /locus_tag="VVO74_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HEU5695055.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYYVENIK"
     gene            complement(7675..10665)
                     /gene="lanM"
                     /locus_tag="VVO74_001021"
     CDS             complement(7675..10665)
                     /gene="lanM"
                     /locus_tag="VVO74_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 lantipeptide synthetase LanM"
                     /protein_id="HEU5695056.1"
                     /translation="MKYKIKNVHKTLFIKERYQILSERNDNSLNNFSLNNWRSTMSII
                     SEKTFEEMLKLNNYNKKIFSNTVNYDYTEEQIRLYSEYAKNSEWYKFAEGSFEIFRKH
                     PQRINFKKDFSRILEPFIINLLKLINNYLENKEYEWIDKNGNIFSSLVFYLEDLIYPW
                     IVKPLVLEINSLREKGLLEGESEQQRYKYFITLFDKEENILNFYNKYPVLLRQISESC
                     LRFYTYFIEILSNLENDFSVLEEELGLRGKLNDIKFGKGDTHSQGKTVLILFFDDAKI
                     VYKPKNLIINNSLNTIAEYIRKVDEKIRIRIPRTIAYSDHSYEEFIDYLPLEQKKKLP
                     EYYYNFGVLLAFIYLFNGSDIHFENLISYGDMPVIIDFETMLQQPLFDDKTGQSLLDT
                     LFHRVTRTLLLPTEGVKREDGLDVEMSALTGNFKKDAFNGQVLINLNTDKVKFDIGKI
                     DFEGGKNLPVRDGDIEFDKYIKDFKKGFRDFYLIFEELNKTEEFKMLLKANLYGLKTR
                     VLFRDTNSYASVLSFLYHPDFYEEMLDREKALENLWSNKFSNQGIVASECEQMRLLDI
                     PIFYTDTNINEIYDDFGNHFISLHQFSGYDYFMKYLPNNNLENLEKQLDIIEIYFPSF
                     DQRKKGYKLNLSNRKKLPNESLVTILHNEVENIADSLVINNIYDEYPIWSIPVNFKGS
                     KWCLEQTGNDMYRGRAGILLFMYYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGL
                     TGDIGYFIVLSIIEDYDTNTLACLNYIKSVLTELEKTDFASVSNKSDYINGLLPLINT
                     LVRYYRRGIEKERVLRLVLSLGDTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYKV
                     TRLKKYKELILQLVPREKIKIHSLKWCSGEFGTLVNHPQSVPEGIVASLDNDTFCHGS
                     MAIINFYIDYMKEMDTSMELESLLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGVTGIA
                     YTFLRYIALNQNDKKIVIPSLLEI"
     gene            complement(10782..10970)
                     /gene="pneA2"
                     /locus_tag="VVO74_001022"
     CDS             complement(10782..10970)
                     /gene="pneA2"
                     /locus_tag="VVO74_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HEU5695057.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
     gene            complement(10977..11201)
                     /gene="pneA1"
                     /locus_tag="VVO74_001023"
     CDS             complement(10977..11201)
                     /gene="pneA1"
                     /locus_tag="VVO74_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HEU5695058.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKICISAAVSGIGGLVSYNNDCLG"
     gene            11666..12529
                     /locus_tag="VVO74_001024"
     CDS             11666..12529
                     /locus_tag="VVO74_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5695059.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEAKELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            12912..13532
                     /locus_tag="VVO74_001025"
     CDS             12912..13532
                     /locus_tag="VVO74_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695060.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            13618..14061
                     /gene="tsaE"
                     /locus_tag="VVO74_001026"
     CDS             13618..14061
                     /gene="tsaE"
                     /locus_tag="VVO74_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU5695061.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            14051..14569
                     /locus_tag="VVO74_001027"
     CDS             14051..14569
                     /locus_tag="VVO74_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5695062.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQAGGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            14577..15593
                     /locus_tag="VVO74_001028"
     CDS             14577..15593
                     /locus_tag="VVO74_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU5695063.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            15678..16934
                     /locus_tag="VVO74_001029"
     CDS             15678..16934
                     /locus_tag="VVO74_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU5695064.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            16989..18155
                     /gene="recA"
                     /locus_tag="VVO74_001030"
     CDS             16989..18155
                     /gene="recA"
                     /locus_tag="VVO74_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU5695065.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            18462..19832
                     /locus_tag="VVO74_001031"
     CDS             18462..19832
                     /locus_tag="VVO74_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU5695066.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     YIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            20208..21164
                     /gene="lytA"
                     /locus_tag="VVO74_001032"
     CDS             20208..21164
                     /gene="lytA"
                     /locus_tag="VVO74_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU5695067.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            21542..21703
                     /locus_tag="VVO74_001033"
     CDS             21542..21703
                     /locus_tag="VVO74_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5695068.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            21690..21896
                     /locus_tag="VVO74_001034"
     CDS             21690..21896
                     /locus_tag="VVO74_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695069.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            21942..22295
                     /locus_tag="VVO74_001035"
     CDS             21942..22295
                     /locus_tag="VVO74_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695070.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKKCY"
     gene            22429..22854
                     /locus_tag="VVO74_001036"
     CDS             22429..22854
                     /locus_tag="VVO74_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695071.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVKEFSLEYMTTGDILVEAFKA"
     gene            23262..24252
                     /locus_tag="VVO74_001037"
                     /pseudo
     CDS             23262..24252
                     /locus_tag="VVO74_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            24242..24793
                     /locus_tag="VVO74_001038"
     CDS             24242..24793
                     /locus_tag="VVO74_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695072.1"
                     /translation="MPANTKVIFQETFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYSLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            24852..25112
                     /locus_tag="VVO74_001039"
     CDS             24852..25112
                     /locus_tag="VVO74_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695073.1"
                     /translation="MRERSATGAQDLSKSIKKHLNDITRLTASLLGDEKLSAIISSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(25876..26275)
                     /locus_tag="VVO74_001040"
                     /pseudo
     CDS             complement(25876..26275)
                     /locus_tag="VVO74_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            26400..26858
                     /locus_tag="VVO74_001041"
     CDS             26400..26858
                     /locus_tag="VVO74_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU5695074.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            26871..27479
                     /locus_tag="VVO74_001042"
     CDS             26871..27479
                     /locus_tag="VVO74_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695075.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            27550..27882
                     /locus_tag="VVO74_001043"
     CDS             27550..27882
                     /locus_tag="VVO74_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695076.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            27893..29308
                     /gene="ply"
                     /locus_tag="VVO74_001044"
     CDS             27893..29308
                     /gene="ply"
                     /locus_tag="VVO74_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU5695077.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            30189..30905
                     /locus_tag="VVO74_001045"
     CDS             30189..30905
                     /locus_tag="VVO74_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU5695078.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            31029..31478
                     /locus_tag="VVO74_001046"
                     /pseudo
     CDS             31029..31478
                     /locus_tag="VVO74_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            31517..32338
                     /locus_tag="VVO74_001047"
                     /pseudo
     CDS             31517..32338
                     /locus_tag="VVO74_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            32345..33316
                     /locus_tag="VVO74_001048"
     CDS             32345..33316
                     /locus_tag="VVO74_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU5695079.1"
                     /translation="MDFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPAQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSIGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQRVAIVGPTGAGKTTIVNLLMKFYEIDKGSIRI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMV"
     gene            33442..33804
                     /locus_tag="VVO74_001049"
     CDS             33442..33804
                     /locus_tag="VVO74_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEU5695080.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGEAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            33801..34304
                     /locus_tag="VVO74_001050"
     CDS             33801..34304
                     /locus_tag="VVO74_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU5695081.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVFIPATGFVILSLLRKKINAPRPYEEWDIKPLLDRDSPGQSM
                     PSRHVFSATIISMTCLHASLTVGFILLVLSALLGLVRVLGGVHYPKDVVVGYICGLAW
                     GVLFFLF"
     gene            34418..34864
                     /locus_tag="VVO74_001051"
     CDS             34418..34864
                     /locus_tag="VVO74_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5695082.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            34870..35544
                     /locus_tag="VVO74_001052"
     CDS             34870..35544
                     /locus_tag="VVO74_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695083.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLAIIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            35705..35896
                     /locus_tag="VVO74_001053"
     CDS             35705..35896
                     /locus_tag="VVO74_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEU5695084.1"
                     /translation="MSYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGAMIANDWVKDNGK"
     gene            36181..36480
                     /locus_tag="VVO74_001054"
     CDS             36181..36480
                     /locus_tag="VVO74_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU5695085.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            36477..36794
                     /locus_tag="VVO74_001055"
     CDS             36477..36794
                     /locus_tag="VVO74_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU5695086.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            36810..37436
                     /locus_tag="VVO74_001056"
     CDS             36810..37436
                     /locus_tag="VVO74_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU5695087.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            37469..38230
                     /locus_tag="VVO74_001057"
     CDS             37469..38230
                     /locus_tag="VVO74_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU5695088.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
BASE COUNT        12088 a         6545 c         7378 g        12308 t
ORIGIN      
        1 gaagaaagtg gctcatgagg tcaggggttt tgtaagttac atctaattga gagaggtatg
       61 aatgatttgg gataaagata gttttctttt aaaacggttg taggaggaaa atctctccta
      121 cactattatt gattctgaga gaaaattgca aaatatcatc taccaaactt tcaattatta
      181 agattttttg cagtttatct gaattagaat cgcaaggctt ctcaataata taattgtcga
      241 attttttcat tctaacttcc tctccattat ttcttccttt atcaagaaaa agttacctca
      301 atattaataa agtacaattc taaattaact ccaattcttg attcatgata atatttcagt
      361 aactcatcgt gcaattaaaa acaaggattt ttatttcaga tgatccatcg tgaacacttc
      421 atcagccatc tcccaaattg ccggattatg tgttgcgata atgattagcc tattatcatc
      481 tcgaagagat agcaaaatct ccataatcaa ctgagaggtt gctgggtcta ttgaagctgt
      541 tggctcatct gccagaataa agggtggatt ctttaagata atttttgcca aggcaacccg
      601 ttgcgattct ccgcccgata actcaaagat gcgcttatct aggtcaagat aagccaggcc
      661 gacctgttct aaagcctgct tctgcctcaa ccgctgttcc gaccgactca acttttgacc
      721 aatgagacct agcttaaggt tttcttcaat actttggttt tcaattaagc caaagttctg
      781 gaagaggtag cccaattcgt gacggaaaaa atcactcgat ttataattgg ccaagtcttt
      841 acctcggtaa aaaatcgtcc catcataagg ttctaatttc ccaatcatgt tcatcaaggt
      901 tgtttttccg ctaccacttg aaccaattaa ggcatagact tttccagcct caaatgtcat
      961 tgaaagattc gaaaataact ctcgttctcc aaaagattta ctcacctgtt taagttcaat
     1021 catattaacc tcccttcaaa acaagaatgg acatcttgtt ttctttctgc atttggacat
     1081 gtaactgtaa aagagataga ccagtaaaga gtaacaagac taagaaagca actcctatct
     1141 ctacctgaag aaatacactc gcaacaaatc ccagtaaaaa cacacccagt tgagcaaaga
     1201 gataagtgcg atggatttct aagaacctga gacctgcaat gcgtttgata aaaatggcac
     1261 gtctaaattc ttcaaagtag agcctattca tagtgttaaa caacaagatt gaagttgcaa
     1321 tcccaagcac agctcctgct agcattaccc aacgttccct ctggatatta tccaataatg
     1381 tgatgtagtt gtggtaacct gtttgcattt ctgagaccca attttcaatg ccttgtctct
     1441 ggataagctc ctgggcatca gacaattgat taaagagaac gtagttctgt actgcgtcta
     1501 tccaaaacaa aatggactgt ggaccagttg attggggtgt tataacaatg atgattggat
     1561 ctttcaaaaa ctgctggtaa gaaatagggg tcgtattata cacaaaacga tcctgacctg
     1621 attctaaata acctaccgta gcagtcattt gctgtcgttc atcttgacta gatatgcgac
     1681 tggttaagtc gtcttcaaaa acagatttat aatgttcttc ctctgaacgg aggtgttcag
     1741 gcagcaataa gacaaactcc cctacatcaa ggtgattcat cttttgactc attttagttg
     1801 aactgtagga cttacttttt cagagggctc caaattttat tttcatttac tttttttagc
     1861 ccataaaata tttaccatac ttataaaaag tagtaatact ccaactaaac tgacttgtaa
     1921 tgaattatat gtattttctg aagtgttagg taaataattt tgagagtacc cttctcgggc
     1981 aatagtaata atattgtgtg tgtttatttg tttaattcca atagtagttt gaattctctc
     2041 ttccaactca attaaattaa cattatctat gaaactatcc caactttgtt catttttata
     2101 ttctaattgt aacatattca aatcatatct caatacgttt ggtatattta acacttttat
     2161 accatttttt actggtaatg tttcttccag aatttttttt acaaacatat aattataggg
     2221 ctgatctttt aatttgtatt tatcaataat cattgcaatc gcaccagaaa ctttaggagc
     2281 agcaaatgag tttccataaa gatacgtata tcctcctagt gttgccgaaa aaatccaatc
     2341 ttctttatat ttttctgcat taataaagtt attaagtcct aattctgaaa gagataatgt
     2401 tgagcctgca ggcgcatata ttgcatcaga atccccttta ttgctaaaat ctgataaatt
     2461 acctaagcga tctatgcctc cgaccgaaat tgtagatgag aaataacttg gaacatcaac
     2521 tactaatcct ggttttctta cttttttgcg tgaactaata agtttcaata aatctgactg
     2581 atttgataca tttagggagt cattccctaa tgcagctact ataattactc ctttttgatt
     2641 cgcgtaatca atagcctttt tatacttcaa aaatgtttca aaatcatttg ttccgtcctc
     2701 atattctcca tcaatcatta aatattgtcc agtactaaga ttgataatat cattgccatc
     2761 atctacagca tcaaaaattg cttttacaat ccaatctgga ctagctgacg acttaccaaa
     2821 tattctatag acgttaatat taacgtgagg atttactcca ttaatattgt catcccctac
     2881 aatttgagct acaacagccg taccatgacc taatctatct tgaatatctg atattattcc
     2941 ttcctctccc tcctcttttc ctaaatatcc tttattgggg acatagtttt ttgagtgatt
     3001 tgaaagattt ttcagtaatc cagtattttg taaatcgact cctgaatcta aaatagcaat
     3061 tgaaacttta gaattacttt tagaatataa tttataactt tcgcctccac cagtaacttt
     3121 atctatatcc cattcatatt ttcttacaat cgacgattct aagttatctt tgtcatgctc
     3181 tatatttcct cctctattat ctagatgaga aacattttcc ttaattttat tatctaaatt
     3241 atcttcgcct agtaaattat tactttcaga gttaacaata tcgttattta tttgtggttc
     3301 aagttccaat ttacaacagt ttttttctaa atgtttatct gttgttacaa ataattctgt
     3361 cttatcgatt tgaatacgaa atttattttg gtctacttct tcttgatttt tattagaata
     3421 gtcaacctgt ttttcatcag attcagaaaa actttcgcta gtctgagtgt gagttatatt
     3481 gccatcaaga tttttaggta tttcttgagc agtaacagaa ttattgaaca aacaaaagaa
     3541 taatatcgct aaagtccaat attttttttt cataatcttc ataaatttac ccttttaatc
     3601 aaaaactaat tatttgaata caattgctta taaatgcctc ctagttcaag aagttctcta
     3661 tgggtcccaa tctctacaat ttcaccatta tgcattacta agatcttatc tgcagacttg
     3721 atagtatcta gtcgatgggc aattaaaatc ttagtggtac cgatttcact taagtaagaa
     3781 gttgtaattt gttgagataa attatctaaa ctacttgttg cttcgtccaa aacaactacc
     3841 gaaggtttcg acaaaagaca acgagctaaa agtatcattt gctgctgccc tccagaaaag
     3901 ttattacctt cttcagcgat gattgtctct aatccaagag gtaaagattt aactacattg
     3961 ctaagaccaa ttgaatttag atttgtcatt aattcttcat ctgaaacaaa gtgtccaaat
     4021 gtcaaattct ctcttaaggt accataactt agggttgaat tttgtaacac tgctccaaaa
     4081 atctttctat acaatgtttg accaatttct tctttttcta ctccatcaac ttctattgaa
     4141 ccaatattag gttctaataa acctaataaa attttagcta atgtactctt acctgaacct
     4201 gattctccaa caatagcaac agtttctcct tttttaatag taacatttat tcctttcaaa
     4261 acataatcat caaataatcc atatttatac caaatatctt ttaattctat ttttttatca
     4321 aattttatat cttgactgac tctttctgga attaattcgg atttagtatt aaacacatcc
     4381 tctattctta aaaaatatcc ctttaataac attaattgta tatagttatc acttaaagaa
     4441 attataggag aaataaagta tggtgagact gtacttattg ctacaatttg tcctaacgtc
     4501 aattgttcga atgtttttat atttacacct acaataaggg tcaaaacagg gagaataatt
     4561 tgtaaaacat tcgttatact actaacaatt gataaatgta tatcaagttt tcgacctatg
     4621 atgagctgtt ttgtattaaa attatcccat ttgttaatcc aaaattcctc ttctccagtt
     4681 agcttaatat cactattttt agaaattact tcggaagtaa tattttgaac attaaccttt
     4741 tcttttatat ttttatcaat taaatttttt gagattttta tgattggata cattacaata
     4801 gatagagcta gacttagtga tattaaaaag attaccatgt acttagaaaa gctaaataaa
     4861 accacagcat aaaccacaat cattaacaaa tcaagtatag ctgctataaa attatttgat
     4921 agtatttctc ttatataaac aatagagtta gctctaaaaa gtatatcccc taaagtacgt
     4981 ttttcataaa aactgtaagg taaatatatc aaatgtttca taaaatcata gctaatctct
     5041 ttatccatta tatattttaa ggatgcaaca tatatctgtc ttaataaata cattagtgag
     5101 aatgaaacag taaatataaa taatatagta aataacattc tagacgaata cgaatcgtcc
     5161 ttgaaattcg tgtcaattat gtatctatta gctataggta ctaatgattg tattacatac
     5221 aataatgctg ttacaaaaaa taaaatccct agcttattcc tatacttaaa aaaatacttt
     5281 aaaacaggcg acttcttatt atctttacga gacataaagc tatctaactt tttaaatgtt
     5341 aaaatgatat ttgaataatg cctttcaaat tcacttattg acattctctg cctgcctttt
     5401 gcaggatcta aaatataaaa cttgttttta ctaatttttt caagaataat aaaatgagaa
     5461 ctctcccaga agcaaatgag tgggaaactg agcggtttta aatctcttac cgaagcttta
     5521 aaagcatgag aacttatatt aaaatctcct aaaactttac ttatagatag gagagaatat
     5581 ccagatctgg atgatgggta gatttcacgt agttcattta aagaaatctc atatttaaaa
     5641 tagttcaata tcatggcaca gcatgctaat ccacattctg aattttccat ttgatatatc
     5701 attggaattt tcacaatact tcctccttgt tcaaaataaa gtcgataatt tcttcttgtc
     5761 taaaatctac taatttcttt agatacttaa tcttttctaa atatttatta tttttcgagt
     5821 aaatatagtt tgacaaggta aaaacaactt cttctaaaga taagttctgt ggaataatcc
     5881 aatcagaaga tttatgtagt aatttatagt actcatggat aatattttcc tgaatatttg
     5941 aatcaaaaac ttcatgatta gcaattgtaa atgctgaccc ttcacctttc acttcaaagt
     6001 aaaggtttat caaacatttt tcaaattttg aaaaaaaaga tttttcttta gaggttaatt
     6061 ttgcaaaatc gtcgattgtt atataaggat tattatagag actgttcgca aagaatctct
     6121 gatatgtttt tgaatctttt gaatacaaaa ctatctctct aatagcattg ccatctgttc
     6181 catcaattgg taaacatacc gtaactagaa aaagaattat attcaaaata aaaaattctg
     6241 atgcgtacgg cacaaatccc aaaagtgcta atattgcgac aattaggtta gctccacctc
     6301 ccccaaagaa gtagaacacc aaattcctat cactattttt ttcattagta atgtttctat
     6361 tactcatttg acaataaccg aatgctaata acactggaaa tttgaaatat attttttttc
     6421 tgaaatagaa gaaaaaggga gtagcaagca tctctagttt ataagataaa catcttccca
     6481 ctaaaaaatg acctagttca tgtaatgtaa ttgatattaa cgaaattaaa atcaatcgaa
     6541 aataatagat taatgaatca tttggaaaaa ttatcaataa taggaacaat aacggaatca
     6601 aacataaata tatgacagag ttatttaata ttttcaacat aataccattc ctctaaacta
     6661 ttagcttcaa aaaggcgttt tttctcccaa tacatcttct caaaatgttc ggaatcataa
     6721 ttttctaaaa ttaattttaa tgtctggtaa gctctttctt gataatccgt tgttttgtac
     6781 ttaattttcc cttcaagtac atcttcaatt ttataagttg cctccatcaa ctgagcctct
     6841 gcaatatctt tgagtgaatt ggtaattgaa acttggtgta atatctgtcc tcccatatat
     6901 gaaaatatat ctctaagata ttctgacaca ttatcagagc cgttactctc agcaacatct
     6961 aatgttacaa caaactttcc agctaatcga aaaagatggc tccacccccc aatcctttca
     7021 ataaagtttt ttgtgtccac agatacgttt tgtaaatata caggagaaga gataattata
     7081 atatcagact ctaataactc tttttttata acacctccat catcagcatt actttgccta
     7141 tcaattcctt tcttaaacaa ctcttctgaa tcagaattag atatttctag ctctgaattg
     7201 aaaggtgtcc tgaaagatat atcaacatta tttctactag aaatgatact tgaaagtctc
     7261 ttagtatact ctaaagtctt agagttatga tttcgcactc ctgcatatat aaatatttta
     7321 ttcattttaa ttcatcctct caatttgaat ttagtagatt tttcaagata gtatggtaca
     7381 aaaacagact tttgttgact cacattatta catatgtttt gtattaaacc aaaatcaata
     7441 ctatttttgg agtaattttg attttagttt aaaatcattt ctataacagt agcatatacc
     7501 tcaagccgtt tagcaattag aatagaacct ttctttatta tattattatc tcaacgaaaa
     7561 gctacactat taaaaatatt ttatagaatt acatattaaa ctagtcaatc ttggtatttt
     7621 tatattgctt aatgagtgga cacctctatt ttagaaacaa aactataaat taagctagat
     7681 ttcaagtaat gaggggataa ctatcttttt gtcattctga ttcagtgcga tataccttaa
     7741 aaaagtataa gcaataccag tcacacctgt atacaaagaa aaatctggga aattgcttgt
     7801 ttggacgata cgatactctc cttcttttga tttattcatt acaacactac acaataaaga
     7861 ctccaattcc atactagtat ccatttcttt catgtagtcg atgtaaaaat ttattatggc
     7921 catacttcca tggcaaaatg tatcattatc taaactagct acaattccct ctggaacact
     7981 ttggggatga ttaactaatg tcccaaattc tccactacac cacttcaaag aatgaatttt
     8041 gattttctcc ctaggaacta gttgtaaaat taattcttta tattttttaa gtcttgtcac
     8101 tttataaata ttttttaatg taaaaattac acctgatagt ccatggccaa aactatatcc
     8161 aaaattacta ttatctctct cgcttacatc attatatagc gtatcaccta aacttaatac
     8221 tagccttaga acacgttcct tctctattcc tctcctataa tatcttacca gtgtattaat
     8281 taaaggtaga agaccattaa tatagtcaga cttgtttgaa acacttgcaa aatcagtctt
     8341 ttcaagctca gttaaaacac tctttatata atttaagcat gcgagagtat ttgtatcgta
     8401 atcctctata atggatagaa caatgaaata tcctatatcc ccagttaaac caaatgtggt
     8461 cttagataaa gaaacagatg gcggaattgc agataacatt ttattgtaca gttgagtata
     8521 tgatgattta tctttcaata attttacata gtacataaac agtaatattc cagctctacc
     8581 cctatacata tcattacccg tttgttcaag acaccattta gaacctttaa aattaacagg
     8641 tatactccaa attggatatt cgtcataaat attattaata accaaagagt ctgcaatatt
     8701 ttctacttca ttatgcagaa tagtaactaa actttcattt gggagttttt ttctattaga
     8761 taagtttaat ttatatcctt tttttcgctg atcaaagctt ggaaaataaa tttcaatgat
     8821 atcaagttgc ttttctaaat tttccaaatt attattaggt aaatatttca taaaatagtc
     8881 atatccagaa aattgatgta gggaaataaa atgatttcca aaatcatcgt agatttcatt
     8941 gatatttgta tctgtataaa aaatcggaat atctaataac ctcatttgtt cacattcgct
     9001 tgctacaata ccttgattag aaaacttatt gctccagaga ttttccaatg ctttttctct
     9061 atctaacatt tcttcataaa aatcaggatg atataaaaaa gatagtactg aagcatagct
     9121 atttgtgtct ctaaaaagta cccttgtctt taaaccatac aagtttgctt ttaatagcat
     9181 tttaaattct tctgttttat ttaactcttc aaatatcaga taaaaatccc taaaaccttt
     9241 tttgaaatct tttatatact tatcaaattc tatatcacca tcccgaacag gcaggttttt
     9301 cccaccttca aaatcaattt tcccaatatc aaactttacc ttatcagtat ttaaattaat
     9361 taaaacttga ccattaaaag catccttctt aaaatttcct gtaagagcac tcatctcaac
     9421 atcaagacca tcctcccttt ttactccctc tgttggaaga agcaaagttc gagtcaccct
     9481 gtgaaacagg gtatccagca aactctgacc agttttatca tcaaatagag gttgctgtaa
     9541 cattgtttca aagtctatta ttacaggcat atctccatag gaaattaaat tttcaaaatg
     9601 tatatcactc ccattaaata aatatataaa tgctaaaagc acaccaaaat tataataata
     9661 ttcaggtaat tttttctttt gctctagagg tagataatca ataaattctt catagctgtg
     9721 atccgaataa gcaatagttc gaggtattct tatcctaatt ttttcatcaa cctttcggat
     9781 atactcagca atagtattta gtgagttatt gattattaaa tttttaggct tgtaaacaat
     9841 tttcgcgtca tcaaagaaga gtatcaaaac agtttttcct tggctgtgtg tatcaccctt
     9901 tccaaatttt atatcattta atttccccct tagccctaat tcttcttcta gcacactaaa
     9961 atcattttct aaatttgata aaatttctat aaaataagta tagaaccgaa gacaagactc
    10021 cgatatttgc ctcagtaaaa cgggatattt gttataaaaa tttaatatat tctcttcctt
    10081 gtcaaacaat gttataaaat atttgtaccg ttgctgctcc gattcccctt caagtaaacc
    10141 tttttcacgc aatgaattta tctctaaaac caaaggttta acaatccaag gatagattaa
    10201 atcttctaaa taaaatacta gagaggaaaa aatatttcca ttcttgtcaa tccactcgta
    10261 ttctttattc tctagataat tattgattaa tttaagcaaa ttaataataa agggttccaa
    10321 aattctagaa aaatctttct taaaattaat tctttgggga tgttttctaa atatttcaaa
    10381 tgaaccctcc gcaaatttat accattccga atttttggca tattctgaat atagtcttat
    10441 ctgttcctcg gtataatcat agttcacagt gttagaaaat atttttttat tgtaattatt
    10501 taatttcaac atttcttcaa aagttttttc agaaataatt gacattgtag aacgccaatt
    10561 atttaatgaa aagttattta aggaattatc atttcgttca gataatattt gatatctttc
    10621 cttaataaac aatgttttat gcacattttt aattttatat ttcatttact tacctcaaac
    10681 ctatacgact tactattgtt ttaaaaaaaa aacctctctc aaaattatta gttacgagag
    10741 aggaaaataa agagcaactt ttatttttaa aattgaatat tttatttttt cttgttgtct
    10801 ttgccacaac gagtctgagc tgaccccaaa tatgatgcaa taaaacttaa tgtagcagaa
    10861 catataattg ttgatctagg gtcagcacca tctgtgccac cataaaccaa ttgcatttct
    10921 tcaagagata attctttcaa actctttccg attacaaaat catttttcat tttaatttac
    10981 cccaaacaat cattattgta gctaactagc cccccaatac cagaaacagc tgcactaatg
    11041 catattttcg agctagctgc agctgatttc aaaataatag gagtaggcgt ccaacgtggc
    11101 tctgcaccat cagatgcacc ataaattaaa ctcatttcat cagcagacaa tgattttaaa
    11161 ctttttccac aaaatttttc gtttgaatta aagttggtca taagtaataa ctcctcctta
    11221 taaaaagtta aataagttgc tctatatttt tcgttttttc agataaatta taattctctc
    11281 attctcgtgc aaaatatcgg gttttaatcc gccttcccaa catcaagacc attggacttc
    11341 ttttgcgatt gcactcgaat ctccaattgt ttattcttct gaataaactg ttggtaagga
    11401 attgtattac taaacataaa aacacctagc aatgcaaatg taactaattt tttaattcca
    11461 cgtttttttc tcatgcaatg aaaccccttt ctttttcctt gtttttattc taacagatat
    11521 attttattta gtcaagtatt tttatgtaat ttttaacttt tttttttgtt tattaccata
    11581 aagaattatt tattccttta acttgctatt ttgaactaaa aactttataa tgaaattaag
    11641 caaataggaa ggtttattat ctttaatgaa tacactcgca gagaaattca gattgaaaag
    11701 aaaagagttg agactctccc aacaaactct tgcagaagga atttgtgaac aaagtcagat
    11761 tagtaaaatt gagagagggc atttcattcc ctccgcagac cttttgttca aactctctca
    11821 acgacttgaa gtaccattag attatttttt taatgaacaa attgaaatta aatctaacct
    11881 ctctaatttc aagcaattgt ctgctcgact attagacgat agaaattatg acgatttgga
    11941 atatatttat agaatagaga ttgaacgaag tacttttcta acactagaag accgaactta
    12001 tcttgaatgg attaaagcta ttattgactt ttatcaatat gacagtaagt gtgaagcaat
    12061 ttcttcattg gaaaatatat tattaaaagt ctcctcaaat actctgattt atttaaaggc
    12121 gttgaatact ctatctaatt tctattcctt agtgggtcgt gaacaagaat atgaggcaaa
    12181 ctactctcat ttaatagagt tgtatcagac aaaaaatttg gaccatcaag agtttttatt
    12241 tggctacatc agagttcgtt acaactacgc tcactaccta gtatcaaagg aaaaatataa
    12301 tgaagccatc caagaagctc ttgagacgat tgaactctgt aaacaaagac agacaagcta
    12361 ccaactggct cctctactta ttcttgtagg aaatgctgga gccaaatttc tagacagaga
    12421 acaagtcaaa aattattata tagaagcaaa agagttatgt aagatttata acaatccttt
    12481 aatgctgatg aagatagaaa attatttgaa ggaattagat actgtttagt taatcttgac
    12541 attatagttt ttctgaaacg ttaaataacc tgtaaggctg atagtgaaat gaatactatc
    12601 agccttatga ttatgtgact attagttcgt ctcgctccgt taggtgcgag acaaaaaaaa
    12661 cacccgctag acggattttc atgatttcaa atttatattc ttcgaaaatc tcttcaaatc
    12721 acgtcagctc tatctgcaat ctcaaaacag tgttttgagc aacctgtggc tagctaccta
    12781 gtttgatctt tgattttcat tgagtattag tctctagtgt ttgtttagcg tcttaaagag
    12841 acatttgaga agattagaaa cagttctctc ttttctccta gtataatgat tggtaggaag
    12901 ggagagagaa gatgaaatca atgagaatct tatttttgtt agctttaatt caaatcagtt
    12961 tgagtagctg tttcctatgg aaggaatgca tcttgtcctt taaacaaagt acagcttttt
    13021 tcatcggaag catggttttc gtttcaggaa tctgtgctgg agtaaattat ctttataccc
    13081 gtaagcaaga agtccatagt gtcctagcca gtaagaagtc ggtgaagctt ttttacagta
    13141 tgttactctt aattaatttg ttaggagctg ttcttgtttt gtcagataac ttgttcatca
    13201 aaaatacgct gcagcaagaa ttagttgact ttttattgcc atccttcttt ttcctatttg
    13261 ggctagattt gctgattttt ttacccttga aaaaatacgt gcgcgatttt cttgctatgc
    13321 tagacagaaa aaagacagtg ttggtgacta ttttagcaac acttcttttc ttaagaaatc
    13381 caatgaccat tgtctcactt ctgatttata ttggactggg cttgtttttt gcagcctatc
    13441 ttgtcccaaa ttcggttaag aaggaagttt ccttttatgg tcatattttc cgagatcttg
    13501 tattggtcat tgttacgctc attttctttt agagaaagcc tgttttttat ggatgttatg
    13561 atgataagtt tagtaggaaa atagacacaa aagaaaagtt tttggtataa taagagtatg
    13621 tacacaaaaa atgaagaaga gttgcaagcc ttaggggagc gtttgggcca tctattagca
    13681 aagaatgatg ttttaatctt aactggagaa ctgggtgcag gtaaaacgac ctttactaaa
    13741 ggacttgcaa aaggattaca gatttctcaa atgattaaaa gtcccaccta tactatcgtg
    13801 agagagtatg aaggtcgact tccactttat cacctagatg tttatcgtat tgaaggagat
    13861 gctgattcta tcgacttgga tgagtttatc tttggtggcg gcgtgactgt tattgagtgg
    13921 ggaaatctct taggagatgc cttgccagat gcttatttag aattggaaat tctaaaagaa
    13981 gcagatggac gccgtttaaa ttttcaggca aagggtttgc gtgctgagaa attgttagag
    14041 gagcttcaat atggagtatg aattgctcat tagggaagca gagcccaaag atgcagctga
    14101 attagtggcc tttttaaatc gtgtgagttt ggagacagac tttaccagcc tagacggaga
    14161 tggtattctc ttgactagtg aggagatgga aatattcctc aacaagcaag ctagttcgga
    14221 caatcagata accttacttg cattcttaaa tggcaaaatt gctggtattg taaatattac
    14281 agctgatcag cgtaagagag tccgtcatat tggagatctc ttcattgtga ttggaaaaag
    14341 atattggaat aatggcttgg gaagtttgtt gctagaagaa gcgatagagt gggcacaagc
    14401 aggtggcatt ctgcgtcgtc tccaactgac tgtccaaact cgtaatcaag cagcagtcca
    14461 tctttatcaa aagcatggct ttgtcattga aggtagccaa gagcgtgggg catatataga
    14521 agaagggaaa tttatcgatg tttacttgat gggtaaactg ataggttagt agaaatatgg
    14581 ttaaaaaaat tattggaatg gtgctagctt tactttctgt aactgtagta ggagtaggtg
    14641 tttttgctta tactatttat caacaaggga cagaaacctt agctaaaacc tataaaaaaa
    14701 tcggcgaaga aaccaaggtt attgaagcga ctgaacctct aaccattctg ttaatgggag
    14761 tggacaccgg aaatgctgaa cgaactgaaa cttgggtcgg tagaagtgat agcatgatct
    14821 tgatgacagt gaatcctaaa acgaaaaaaa caacaatgat gagtttagag cgggatattc
    14881 tgacgcgcat tgaatcaggg aatggtcagg ctcatgaagc gaaactgaac tcagcatatg
    14941 cagatggtgg agcagagctt gctatagaaa ccattcaaaa aatgatgaat atccatattg
    15001 atcgctatgt aatggtcaat atgagagggt tgcaaaaact agtggatgca gtaggaggta
    15061 ttacagtcaa taatatccta ggtttcccaa tttctatcag tgaccaagaa gaatttaata
    15121 ctatttctat cggtgttggg gagcaacata ttgggggaga agaagcccta gtctatgcac
    15181 gaatgcgtta ccaagatcct gagggggatt atggtcgtca aaaacgtcaa cgtgaagtta
    15241 ttcaaaaagt catggaaaaa gctctcagtt taaatagcgt tggtcattat caagagattc
    15301 taaaagcttt gagtgacaat atgcagacca atattgattt gtctgcaaaa agtatcccta
    15361 acttgctagg ctataaagat tcatttaaaa ccattgaaac tcagcagttg cagggtgaag
    15421 gagagatact tcaaggtgtt tcttaccaga ttgtttcgag agcacatatg ttggaaatgc
    15481 aaaatatact ccgacgttct ttgggacaag aagaagttac tcagcttgaa accaatgcgg
    15541 ttttatttga agatttattt ggcagagcac ctgttggtga tgaagataat taacttttga
    15601 tacaaataaa aaaatcaatc gtaggaaaat tcctgcgatt ttttcaaaaa aatacgaata
    15661 gataggtagg aggaaacatg aaagcagaaa tcattgctgt tggaacagag attttgacag
    15721 gacagattgt caacaccaat gcccagtttt tgtcggaaaa actagctgag attggggtag
    15781 atgtatattt tcagacggct gtaggagaca atgaagttcg tctcttgtct ttgcttgaga
    15841 ttgccagtca acgtagcagt ctggtgattt tgacaggcgg tttggggcca actgaggacg
    15901 acctaaccaa acaaacccta gctaaatttt tagggaaagc attagtcttt gatcctcagg
    15961 ctcaggagaa gttggatatc ttttttgccc tgcgaccaga ctatgcccga acaccgaata
    16021 acgaaagaca agctcaaatt gtagaaggag cgattccact gccaaacgaa acaggactgg
    16081 ctgttggagg aaaattagaa gtagacggag tgacctatgt cgtccttcca ggtccgccaa
    16141 gtgaattgaa acccatggtc ttaaaccaac ttctacccaa gttgatgaca gggagcaagc
    16201 tgtattcccg agttcttcgt ttctttggga ttggcgagag ccagttggtt acgattttgg
    16261 ctgatttaat tgataatcag atcgatccta ccttggcccc ttatgccaag acaggagaag
    16321 tcactctacg tctgtcaaca aaggctagca gtcaagaaga ggcgaatcaa gcgctggata
    16381 tcttggaaaa tcaaatcttg gactgccaga ctttcgaagg aatttcttta cgagactttt
    16441 gctatggtta tggggaagaa actagtttag ccagcattgt ggtagaagaa ctgaaaaggc
    16501 aagggaaaac catcgcggct gcagagagtt tgacggcagg tcttttccaa gctaccgtgg
    16561 cgaatttttc tggagtttca agtatattta agggtggttt tgtgacctat agcttggagg
    16621 aaaaatcaag gatgttggat attcctgcca agaatttgga agaacatggt gtggtgtctg
    16681 aatttacagc tcagaagatg gctgagcagg cacgaagcaa gacccagtct gattttggaa
    16741 ttagtttgac cggagtggca ggaccagata gcctagaagg acacccagtt gggacagtct
    16801 tcataggctt ggcgcaagag caaggaactg aggttatcaa ggttaatatt ggaggcagaa
    16861 gccgagcaga tgtacgtcat attgcggtta tgcatgcctt taacctagtt cgcaaggctt
    16921 tattaagtga ctaacttttg atataatagt agataggtct gaggatcatt agaatgtagg
    16981 agaatagaat ggcgaaaaaa ccaaaaaaat tagaagaaat ttcaaaaaaa tttggggcag
    17041 aacgtgaaaa ggccttgaat gacgctctta aattgattga gaaagacttt ggtaaaggat
    17101 caatcatgcg tttgggtgaa cgtgcggagc aaaaggtgca agtgatgagc tcaggttctt
    17161 tagctcttga cattgccctt ggctcaggtg gttatcctaa gggacgtatc atcgaaatct
    17221 atggcccaga gtcatctggt aagacaacgg ttgcccttca tgcagttgca caagcgcaaa
    17281 aagaaggtgg gattgctgcc tttatcgatg cggaacatgc ccttgatcca gcttatgctg
    17341 cggcccttgg tgtcaatatt gacgaattgc tcttgtctca accagactca ggagagcaag
    17401 gtcttgagat tgcgggaaaa ttgattgact caggtgcagt tgatcttgtc gtagtcgact
    17461 cagttgctgc ccttgttcct cgtgcggaaa ttgatggaga tatcggagat agccatgttg
    17521 gtttgcaggc tcgtatgatg agccaggcca tgcgtaaact tggcgcctct atcaataaaa
    17581 ccaaaacaat tgccattttt atcaaccaat tgcgtgaaaa agttggagtg atgtttggaa
    17641 atccagaaac aacaccgggc ggacgtgctt tgaaattcta tgcttcagtc cgcttggatg
    17701 ttcgtggtaa tacacaaatt aagggaactg gtgaccaaaa agaaaccaat gtcggtaaag
    17761 aaactaagat taaggttgta aaaaataagg tagctccacc gtttaaggaa gccgtagttg
    17821 aaattatgta cggagaagga atttctaaga ctggtgagct tttgaagatt gcaagcgatt
    17881 tggatattat caaaaaagca ggggcttggt attcttacaa agatgaaaaa attgggcaag
    17941 gttctgagaa tgctaagaaa tacttggcag agcacccaga aatctttgat gaaattgata
    18001 agcaagtccg ttctaaattt ggcttgattg atggagaaga agtttcagaa caagatactg
    18061 aaaacaaaaa agatgagcca aagaaagaag aagcagtgaa tgaagaagtt ccgcttgact
    18121 taggcgatga acttgaaatc gaaattgaag aataagctgt taaagcagtg gagaaatccg
    18181 ctactttttc gatttttgat tcaagttttt agattatata tagtagattg aaataagata
    18241 tgaacaactt tattaggaaa gtcaaattaa tttctagaaa tgttttagca gctacagcgt
    18301 actattccaa actcaaccaa ctataataga tcgaaactag aatagtacac atctacttct
    18361 aaaacattgt taaaaatcga tttgactgtc cttatttcat tccgctatat ataagtttgc
    18421 tgtttcttgt cgctcctctg gaaagctgat ataatagctt tatgaataaa aaacgaacag
    18481 tggacctgat acatggtccg attcttccct cgctcttaag cttcaccttt ccaatcttgt
    18541 tatcaaatat ttttcaacag ctctataaca ctgctgatgt cttgattgtt ggacgatttc
    18601 ttggtcaaga atccttggct gcagtaggag cgacgacagc gatttttgat ctgattgtag
    18661 gttttacact tggtgttggc aatggcatgg ggattgtcat tgctcgttat tatggggctc
    18721 ggaatttcac taaaatcaag gaagcagtag cagccacctg gattttaggt gctcttttga
    18781 gcattctagt tatgttgctg ggctttcttg gcttgtatcc tctcttgcaa tacttagata
    18841 ctcctgcaga aattcttcct caatcttatc aatatatttc tatgattgtg acctgtgtag
    18901 gtgtcagctt tgcttataat ctttttgcag gcttgttgcg gtatattggt gacagtctag
    18961 cagccctggg atttctgatt ttctctgcct tggttaatgt ggttctggat ctctatttta
    19021 ttacgcaatt gcatctggga gttcaatccg caggacttgc taccattatt tcgcaaggtt
    19081 tatcagcggt tctctgcttt tattatattc gtaaaagtgt gccagaactc ttgccacagt
    19141 ttaaacattt caaatgggac aaaagcttgt acgcggatct cttggagcaa ggtttggcta
    19201 tgggcttgat gagttcaatt gtatctatcg gcagtgtgat tttacagttt tctgttaata
    19261 catttggtgc agtgattatt agtgcccaga cggcagctcg acgcattatg acctttgccc
    19321 ttcttcctat gaccgctatt tctgcatcaa tgacgacctt tgcttctcag aatctaggag
    19381 ctaagcgacc tgaccgcatt gttcaaggtc ttcgaatcgg cagtcgttta agtatatcct
    19441 gggcagtttt tgtttgtatt ttcctctttt ttgccagtcc agccttggtt tccttcttgg
    19501 ctagttcgac agatggttac ttgatagaaa atggaagtct ctatctgcaa atcagttcag
    19561 ccttttatcc cattttgagc ctcttgttga tttatcgcaa ttgcttgcag ggcttggggc
    19621 agaagatcct tcctctagtt tctagcttta ttgaactaat cggaaaaatc gtttttgtgg
    19681 ttttgattat tccttgggca ggatataagg gtgttatcct ttgtgaacct cttatctggg
    19741 ttgccatgac agttcaactg tacttctcac tattccgtca tcccttgata aaagaaggaa
    19801 aggcaatttt ggcaaccaaa gtgcaatcct agttggattt actgaataaa atccatttcc
    19861 tctagtgaac atcgaaaaaa cttgtgttct cttcttcagt ttggtgttga aaatagttta
    19921 acagactttt gacttctttt atatgatata ataaagtata gtatttatga aaaggacata
    19981 tagagactgt aaaaatatac ttttgaaaag ctttttagtc tggggtgtta ttgtagatag
    20041 aatgcagacc ttgtcagtcc tatttacagt gtcaaaatag tgcgttttga ggttctatct
    20101 acaagcctaa tcgtgactaa gattgtcttc tttgtaaggt agaaataaag gagtttctgg
    20161 ttctggattg taaaaaatga gttgttttaa ttgataagga gtagaatatg gaaattaatg
    20221 tgagtaaatt aagaacagat ttgcctcaag tcggcgtgca accatatagg caagtacacg
    20281 cacactcaac tgggaatccg cattcaaccg tacagaatga agcggattat cactggcgga
    20341 aagacccaga attaggtttt ttctcgcaca ttgttgggaa cggttgcatc atgcaggtag
    20401 gacctgttga taatggtgcc tgggacgttg ggggcggttg gaatgctgag acctatgcag
    20461 cggttgaact gattgaaagc cattcaacta aagaagagtt catgacggac taccgtcttt
    20521 atatcgaact cttacgcaat ctagcagatg aagcaggttt gccgaaaacg cttgatacag
    20581 ggagtttagc tggaattaaa acgcacgagt attgcacgaa taaccaacca aacaaccact
    20641 cagaccatgt ggatccatac ccttacttgg caaaatgggg cattagccgt gagcagttta
    20701 agtatgatat tgagaacggc ttgacgattg aaacaggctg gcagaagaat gacactggct
    20761 actggtacgt acattcagac ggctcttatc caaaagacaa gtttgagaaa atcaatggca
    20821 cttggtacta ctttgacagt tcaggctata tgcttgcaga ccgctggagg aagcacacag
    20881 acggcaactg gtactggttc gacaactcag gtgaaatggc tacaggctgg aagaaaatcg
    20941 ctgataagtg gtactatttc aacgaagaag gtgccatgaa gacaggctgg gtcaagtaca
    21001 aggacacttg gtactactta gacgctaaag aaggcgccat ggtatcaaac gcctttatcc
    21061 agtcagcgga cggaacaggc tggtactacc tcaaaccaga cggaacactg gcagacaagc
    21121 cagaattcac agtagagcca gatggcttga ttacagtaaa ataataatgg aatgtctttc
    21181 aaatcagaac agcgcatatt attaggtctt gaaaaagctt aatagtatgc gttttcttgt
    21241 ggagatattt ccttcaattt ttgctactat attaaacaaa aatcaaaaag caaactagaa
    21301 agttatgctc aaataaaatc taaatttgac aatgtaaacc gagtcggata gctttaagta
    21361 ctgttttgag gttgaagata cgatttttga taggaactca tcaaataggt ttaatatcat
    21421 caattttaga tttttaagta gcatcaataa attgcttcct tgttttgtca taattttttt
    21481 atttaaaaaa ttatgacaag agtgtgctat tctttttatg agaggtgtat gaatatgata
    21541 aatgtatgtg ataaatgtat gtgatgttgg aaaaagaata aaagaactta gaatatcttc
    21601 aaatcttact caagataaga ttgctgagta tttgtctttg aatcaaagca tgattgccaa
    21661 aatggaaaaa ggtgaaagga atatcacgaa tggatttaag taataaagct ccaaatctta
    21721 gaaaaaagtt gggagctgat ggtgaatcgc cgatagatat ttttaaattg gtacaaaaga
    21781 tagaaaattt gacgctggta ttttatggac tcggaaagaa tattagcgga gtctgttata
    21841 aaggaactca gttcagtctc attgcagtca attcagacat gtcattagga aggtaaagat
    21901 tttctttagc acatgaactg tatcatcttt attatgatga ggtgaagaag agttcagtca
    21961 gtcttatctt gattggtgaa ggagatgaaa ctgaaagaaa agcggatcag tttgcttctt
    22021 attttttaat tttcccatct tcactgtata ggatggttga ggaaatcaga gaaaatgcca
    22081 atagaactca tcttgaagta gaagatatta taaaattggg tcagttttat ggtatcagtc
    22141 ataaagctat gttatataga ttgaggaatg atggatacct tgatgcagaa gaaattaaaa
    22201 atatggatat tagtgttata gagacagctt caagattagg ctatgataca agtttatatc
    22261 gtcctttgtc agaaagtaaa aagaaatgtt attaggataa tatattaatc taactgaaca
    22321 acttttagaa aataacagaa tttcgcaagg gaagtatgag gaactgttac tagatgcttt
    22381 cagatatgat attgtatatg ggctagatga agagggggga gttgtcgttt gactagtcgt
    22441 gtatttattg atgcagattg tatttcagta tttttatggg ttggcactga acatctttta
    22501 gaaaagctct atttgggtaa aattgttatt ccacaagagg tgtatgatga aatcaatata
    22561 cctacaattc cccatttaaa atctaggata gatcagttgg tagctaaggg ttcagctgag
    22621 attgtgagca tagacattgg aactgaagaa tacgcattat atagagattt aacaagaaat
    22681 catgatagta acaagattat tggtaaggga gaagcggctt ctatttcctt agcgaaaaag
    22741 cataatggga tattaggaag taataaccta agagatgtta aatcatatgt aaaagaattt
    22801 tctttagaat atatgacaac aggagatata ctggttgaag cgtttaaagc gtaatttatt
    22861 actgaacaag agggcaatca tatctggaat aatatgctta aaaagagaag gaaaattggt
    22921 gcaaattcat tttcagacta tcttcgtgga agtattcatc aaaatagaca aaaataaatt
    22981 tggataaatc gaactcacta ttcaggaggc atatgagcaa ttcgaaaaag aaaagtgtca
    23041 aattgagcct ataggagtag aagtgaaata gtaagtcctg catagtggat gagagaaaag
    23101 ttctccttga agttttcctg aactatcagt cgcatgtcaa acgatatgta gggtaatgtg
    23161 agaggggata gcgagtagtt tttggttatt ttatcaaaaa acttatattt tattataccg
    23221 aatgataaaa tataataaaa atgatagaat aaggaaaaaa catgaatgtc aaaaagataa
    23281 tgtcaatttt tcaatccttt tatgttgatg tcagtattga ggaactgact ttaccaatca
    23341 gttttgtaaa aaagtttgag tatactcaaa tgacttttca taaggaatca tttttattga
    23401 ttaaagaaaa gagaaggggg agtttgagtt catttgttac tcaggctcgc actatgggtg
    23461 ataaagccaa tatggatgtt gttttggtgt tttcgaagtt atcagacggt gaaaaaaaag
    23521 caattacttc aagctagagt tccgtttgta gactttaagg gaaacctctt cttccctaca
    23581 ttgggactag tactgaatgc gaatgatact gaagtcccta aggaattaat acctagcgaa
    23641 caattaacgt ggattgcctt tttattgaca aaaggtcaaa aagtagtaga tgttgatttg
    23701 ctttcacaag tcactggact tccaaactca acaatttata ggtgtttgag gacttttaaa
    23761 gctttatatt tgttaaacaa gcaaaataag ctttacacat atacggtgtc aaagaaagaa
    23821 ttattcttaa aatccgtgtc atgtttattt aatcccatca aaaaacggat tttattgcca
    23881 gatggcgata taaagcagat aaaatctgtt tctaaccttc tatatggtgg tgcttatgct
    23941 ttgtcgcatt caactttttt agctgaaacg gatgaaaata ttagctatgt catatggcag
    24001 agaaaattca atcagttacc cttgccactt tctcagcata ttttaaaagg aaagatgcta
    24061 gagatatgga aatatcgtcc ttttgtatct gagttttgga atgattttaa aaataatcat
    24121 gataaacaat ttgtagatcc gatttctctt tatttgacct taaaagatga tgatgaccca
    24181 cgtatagagg aagagagtga agcactagaa aatatgatat tacagtatct gggagaagat
    24241 gatgccagct aatacgaaag ttatttttca agaaacgttt gcggattttc agaactatta
    24301 tgttctgatt gggggaactg ctacctctat cgtattggat tcgcaaggat ttaaaagtcg
    24361 cacaacaaaa gattatgata tggtcatcat tgatgaagta aaaaataagg aattttatac
    24421 taccttgaat cattttttag aattgggaga gtatcaagga agtcagaaag atgagaaagc
    24481 gcagcttttt cgatttacaa caactaatcc tgagtttcct tctatgattg aactatttag
    24541 tatcttacca gaatattcat taaagaagga cggtcgagaa attcccttac attttgacca
    24601 agatgctagt ttatcagcct tattattgga tgaagattat tataatatat tggtgcatga
    24661 aaaagaaacc attcaggggt attcggtatt gagtaattgt ggtctatact cttcgaaaat
    24721 ctcttcaaac cacgtcagct tccatctaca acctcaaaac agtgttttga gcagcctgca
    24781 gctagcttcc tagtttgctc tttgattttc attgagtatt aattattttt aaggctaaag
    24841 cttggctgga tatgagagag cgctctgcta caggtgctca agatttaagt aagtccatta
    24901 aaaagcattt gaatgacatt acccgtttga cagcttcctt gctaggagat gaaaagttat
    24961 cggctataat atcaagtagt gcggtaaaag cagacatgca ccgctttgtg atagaattag
    25021 agcctgtgaa gtcaactatt cttcaaaatg atgacatttc attggatcaa aatgaaattt
    25081 ttgaaattct gaaaaatttt ctcgatggtt aaaataattg tagcgagatg gctatattga
    25141 attcgtctat atctggaaac tagaaaaaac ttcaatttca ggagaaaatg aagtcaatct
    25201 tcccacaatc aaacgtatag tatcaaggtt tttcaagacc tgatattatg cgttttttgc
    25261 ttttcaaaac tttttgccca gtctttgttt ttatcctcta gtcacttgat ttgtttcagg
    25321 tggtttttta gtatagtaaa atgaaacgag aacaggacaa attgatcagg acagtcaaat
    25381 cgatttctaa caatgtttta gaagcagaag tgtactattc tagtttcaat ctactatagt
    25441 taaatctgcg gtcaagtcta ctggtgaatc tatgattgta atactcttcc aaaatctcat
    25501 caaccacgtc agtcttgcct tgcagtctgt atcttactga ccaagctagt gatggactta
    25561 gaataggtga tttggagcgt cctattggct aggaaatgct gatcatagtc ctttgctgag
    25621 gctagggtgt ttcaacattc aacactcaac tggttgatct agttgatagg aagggaatta
    25681 ctataaaata ctcaggcttc catcatattt tttgaaacga ttgtgtaatc aaaatgtacc
    25741 aatattgtag tattggtaca gaagatgttg tgaatggata aatatatcat aactgctgtc
    25801 tctctatgta aaaagaaggc tgtatcaaaa agatttcata tgtctgtgca tatatataat
    25861 agacttcctg caaaactaga atcctagttc atgattgata ataccagcac tcaaattcat
    25921 tcgtaatccg aagcgtttac gatgatttcg acaggttgtt gaaaacattt taaacgtttt
    25981 tactttggca aagatgttct caaccttgct tctctcctta gatagcgcat ggttatagac
    26041 tttatcttca actgttagtg gcttgagttt gctggattta cgtggagttt gtgcttgagg
    26101 atatatcttc atgagccctt gataattact gtcagccaag attttaccag cttgtccgac
    26161 ttttttgata agctgttttt aatacagcta acatctcttc aaaagtggta cgctgaacac
    26221 caacaagacg cttaaatcgt gtatcagtta attgtttact tgcttcataa ttcatagaac
    26281 tactatacca tattttgttt cgcagggagt ctaataagtt atagtccagt ttttactata
    26341 ctttgatatt caaatatgtt atactatggt tatcaaagta aatgaaagga gttacgaata
    26401 tgacgccaga agaaatgtac ctgacagagc gattagacgt acagatagct cattttttaa
    26461 agaaaagcgt tcaacatcgt aggcgctata aggtattaaa aataacagaa atcgtggcag
    26521 gtttcctcat agctgtcttt tgtgctattc ctatgccagg tgatcgctac cgtttgattt
    26581 cggttgcctt atccagtctc ggcttgctgt gtgaggggat tatcaatttg tataatgcaa
    26641 aggaaaattg gatttcttac caaaaaactg cgcaactcct ggagaaagaa aaattcctct
    26701 atcaatgcca aacggagaaa tatgcaggaa agaccaaggc ttttgcccta tttgtcaaga
    26761 catgcgaagg tcttatctca gaggagatta accagtggga aagtatccag tcaaaagaag
    26821 tggcagctag tgcagatgct ccagttaaaa aagagtagga ggtagaggaa atgtctcaat
    26881 ccagctacct gtcgcccttg ctctggttaa aaaaagaagc cgataaggaa aagatgagcg
    26941 cgacccagtg ccagatattt ttcttttact atcaaatgtt tgagctctta tttgctagag
    27001 aaagcgacat gaaagactta tgtctgggaa cgaaaggttt ttatttctcg cagttagaga
    27061 aaaatttgct ttctggagtt tcccgatttc taaaaaactt ggaggggaaa gtaactctca
    27121 aggctaacca agaagtatca gctcgcaaag ccctttttct agccttgaca actagccaat
    27181 cagattggca ggagttagct cctgtttttg atttttatca gactatcggg aggcttgaaa
    27241 atccttctct cttgagttct caggacagac aacatctgat gtggatttac cagtcagctt
    27301 tggagaagga ttatattgtc aaggttattg gcgacaagca ttttgtattg aagagacaag
    27361 atgctactaa attgacagcg cgccaaactc aaactttgga aattctgagt caatcagaag
    27421 acttggtcaa tcctgtctat gttacattag gagaaaaggg ggtgctcttg cttgattaag
    27481 agaggagatg ttgtagctct ttatttgcct tttccgacta ttagtagcga tttggctgtg
    27541 aagaatcata tgtatatctg tattgacaac agcatgacta aaaacaaaga gttggttaaa
    27601 aatcagacct tcaaaccagc tctcttgacc agacgtttgg tcaagaactt tatgatagaa
    27661 gagccggatc tagctcgtaa tccttttaca agaccaacct tgattgactt agataaggta
    27721 tttatgttgg ataatacggt tattccgact tcttatctag ccagacggcg acgcaatgtc
    27781 tcagaagaat tgtacgagga aattttggat cacttagtcc aaccacggct gatttcgctg
    27841 aacaagtctg agtttatgca actcaatcca ggaacttatt aggaggtata agatggcaaa
    27901 taaagcagta aatgacttta tactagctat gaattacgat aaaaagaaac tcttgaccca
    27961 tcagggagaa agtattgaaa atcgtttcat caaagagggt aatcagctac ccgatgagtt
    28021 tgttgttatc gaaagaaaga agcggagctt gtcgacaaat acaagtgata tttctgtaac
    28081 agctaccaac gacagtcgcc tctatcctgg agcacttctc gtagtggatg agaccttgtt
    28141 agagaataat cccactcttc ttgcggtcga tcgtgctccg atgacttata gtattgattt
    28201 gcctggtttg gcaagtagcg atagctttct ccaagtggaa gaccccagca attcaagtgt
    28261 tcgcggagcg gtaaacgatt tgttggctaa gtggcatcaa gattatggtc aggtcaataa
    28321 tgtcccagct agaatgcagt atgaaaaaat cacggctcac agcatggaac aactcaaggt
    28381 caagtttggt tctgactttg aaaagacagg gaattctctt gatattgatt ttaactctgt
    28441 ccattcaggc gaaaagcaga ttcagattgt taattttaag cagatttatt atacagtcag
    28501 cgtagatgct gttaaaaatc caggagatgt gtttcaagat actgtaacgg tagaggattt
    28561 aaaacagaga ggaatttctg cagagcgtcc tttggtctat atttcgagtg ttgcttatgg
    28621 gcgccaagtc tatctcaagt tggaaaccac gagtaagagt gatgaagtag aggctgcttt
    28681 tgaagctttg ataaaaggag tcaaggtagc tcctcagaca gagtggaagc agattttgga
    28741 caatacagaa gtgaaggcgg ttattttagg gggcgaccca agttcgggtg cccgagttgt
    28801 aacaggcaag gtggatatgg tagaggactt gattcaagaa ggcagtcgct ttacagcaga
    28861 tcatccaggc ttgccgattt cctatacaac ttctttttta cgtgacaatg tagttgcgac
    28921 ctttcaaaat agtacagact atgttgagac taaggttaca gcttacagaa acggagattt
    28981 actgctggat catagtggtg cctatgttgc ccaatattat attacttggg atgaattatc
    29041 ctatgatcat caaggtaagg aagtcttgac tcctaaggct tgggacagaa atgggcagga
    29101 tttgacggct cactttacca ctagtattcc tttaaaaggg aatgttcgta atctctctgt
    29161 caaaattaga gagtgtaccg ggcttgcctg ggaatggtgg cgtacggttt atgaaaaaac
    29221 cgatttgcca ctagtgcgta agcggacgat ttctatttgg ggaacaactc tctatcctca
    29281 ggtagaggat aaggtagaaa atgattagga gagaagaatg tttgcgacaa aaagaggcga
    29341 tgagctctct gcgaatatct gaaagtttat ctcttgccta gcgatttcca ttggagtatg
    29401 ctcgtgatgt taaaatgaat ctatcaaaca gaatgtgtaa aaaagtaaaa agggtagcca
    29461 attccttgat atacagggga ttgattatcc tttacttgtt ttagatgatt ggaaattcaa
    29521 gaatgacacg tatcggaaat attttgctgt ttatatctaa tacccattta tggaaaaaat
    29581 gaaattaaat atgaacaaat caattgctag caatggttta gaagtgccag tgtactagtc
    29641 taatttctcc atcttgggaa cacgtaaatt atactcttcg aaaatctctt caaaccaggt
    29701 cagtcctatc cgcaacctca aaacagtgtt ttgagcaacc tgcggctagc tttctagttt
    29761 gctttttgat ttttattgag tattagaggt ttgcttagaa actcttctat tgatttctta
    29821 gaatacaata gcgcctataa gaactgttga atttcaaagt atttacttga actatgatat
    29881 gtctggagta gactgtcaac aaaaggtgca gtatgattgt ttttgtcgct tatatctaca
    29941 aacttcaaac agtaatttga gctgactttg tcaaacttgg ctgaaacttt ctatttgcag
    30001 ataatggtct agtttgtttt ttgaatgtgg atgagtgtct gttgataaag atagaaaggc
    30061 aagaccatct tagcaggtaa agtgctatcc tagcttgatt tgctaataaa atccatttcc
    30121 tctagtgaaa atcaaaaaaa cttgtgttat aataagaaag attaaaatgt gaaaaaagga
    30181 gattcctaat gggacgtaaa tgggccaata tcgtagccaa gaaaacggct aaagatggag
    30241 ctaactctaa agtatatgca aaatttggtg tagaaatcta tgtagcagct aaaaaaggtg
    30301 atccagatcc agaatcaaac tcagctttga aattcgttat cgaccgtgct aaacaagccc
    30361 aagtgccaaa acacattatc gataaagcga ttgataaagc caaaggaaac acagacgaaa
    30421 cctttacaga aggacgttac gaaggttttg ggccaaatgg ctctatgcta attgtggata
    30481 ctttgacttc taacgttaac cgtacagcag ccaatgtccg tgcagccttt ggtaaaaacg
    30541 gcggaaacat gggcgcttca ggttctgttt cttacctttt tgacaacaaa ggtgttattg
    30601 tatttggagg tgaagatgcg gacgcagtct ttgagcaatt gctcgaagcg gatgtggatg
    30661 tggatgacgt agaagcacaa gaaggtacaa tcacagttta cacagcgcca actgaccttc
    30721 acaaggctat cgttgctctc cgtgagtctg gtattgaaga attccaagtg actgaattgg
    30781 aaatgattcc tcagtcagaa gtggaattgt caggcgaaga ccttgaaacc tttgaaaaac
    30841 tttacagcgt tcttgaagac gacgaagacg tccaaaagat ttatacgaac gtagatgggt
    30901 tttaatttaa cctatagaac atgatcctaa gtgagaaaat cacttgggat ttttttaatc
    30961 aagaaaatag ttctcataga aatttaatta ttctccagag aactattttt atttagaagg
    31021 gggagattat ggataaaccg atgttagtct ttaagcgttt tggtcatcaa atttacctga
    31081 tggtgcaaaa ggaagccaaa cgttgcggca ttgaatttat gggtgggccg caaggtcagg
    31141 ttgtgcgttt tttggataat cgctagaaaa atcaagactt ggtcttgatt aaagatatcg
    31201 agcaggaact caatattacc aagtctgttg ctagtaatct ggttaagcgt atagtgcaaa
    31261 atggtttggt ggaattggag gcgagtcctg ttgataagcg ggctaagttt gttcgtctga
    31321 cggacaaagc acgttctcag atgcaacagg ttaaggcttt ttttgaacgc atagacaagc
    31381 agttgatgga agacattgat gaagatgaat tactgatttt tgagaaagtt ctcggtcaac
    31441 tacaggcaaa atatcaaggg aataggagga gagaataaag aaattaacca aaagaattag
    31501 tagaaaagaa tgggggatga ttttactagc cattctcttt acttgctttt cggtctatct
    31561 agagttggaa gtgccgacct atatctcgaa aattacggat ttgctaggta gtcaagaaac
    31621 taatttagat gagttgtggc agccggcaag catgatgatg ggaatgccct ttcttgcctt
    31681 cttgtccgta gttgcagttg gattttttgc atcccgagtg gcggcttctt atactagtag
    31741 gctgagaagt gatattttta accgagtttt ggattactcg cagacagaga ttaagaaatt
    31801 ttcaattcct agcctcttga tgcgtactac caatgacatt actcaagttc aaatgttgat
    31861 tactatggac ttgcaagtgg taacgtgtgg tccaattatg gctatctggg ctattgggaa
    31921 gattttaggt cattcagaat actggctctg ggccgtactt gtggcagtga ttgtcaacgt
    31981 cctgatgacg accgttttga tgacgctagc ctttccaaaa cagtccttga ttcaggggct
    32041 gacagataaa ctgaacagta tcactcgtga gagtttaaca ggtattcgtg tcgttcgtgc
    32101 ctacaatgca gaggattatc aaaatgaaaa atttgcagca gtaaatgatg aattgacccg
    32161 ttaaaatttg tttgtcaacc gtcttatggc tattttgaat cctatcatga tggggatttc
    32221 aagtggtttg agtgtggcga tttactggat tggggcctat gtgattaacg acgctgctcc
    32281 gatagcgcgt ctgcctctct ttagtgacat gattgttttc atgtcttatg ccatgtaggt
    32341 tgtcatggac ttccttctca tgggagcact cttcatcgtt cttccccgaa ctatggtctc
    32401 tgctaagcgg attaatcaag ttttagattt gcattcttct atccaaaacc ctgctcaagt
    32461 gcagctgact gatgaaaact tcaaaggtca ggtcgagttt aaggatgtga ccttccgcta
    32521 tgcggcaaat tcggaggcag ttattgaaca tgttagcttt aaagcagaaa ctggtcaaac
    32581 agtggccttt attgggtcaa taggttctgg taaatcaact ctggtcaatc tgattccacg
    32641 tttctacgac gtgtcagcag gagaaattct ggtggacggt gtcaatgttc aagactatga
    32701 cttctctgcg acagctcatg ctggtcaaag ggttgccatt gttgggccga ctggggctgg
    32761 taagacaacc attgtcaatc ttttgatgaa attctatgag attgataagg gaagtattcg
    32821 cattgatggt gtggatacca aggctatgac gcgttcagaa gtgcatgatg ccttttcaat
    32881 ggtcttgcag gatacctggc tctttgaagg aactattcga gacaatctca tctataatca
    32941 aatagggatt agtgatgaac gaatgatgga agctagtaag gctgtgggaa ttcaccactt
    33001 tattatgacc ttgccagatg gctatgatac catcttggat gacaccgtga ccttgtctgt
    33061 aggacaaaaa caactattga ctattgctcg tgcccttctt aaggatgcac cgcttttgat
    33121 tttggatgag gcgacttctt ctgttgacac acggacagag gaattgatcc aaaaagccat
    33181 ggaccgtttg atggaaggac gcacatcctt tgtcattgcc caccgcttgt caaccatccg
    33241 aaatgcagac ttgatcttgg tcatgaaaga tggaaatatc atcgagcaag gcaactatga
    33301 ggaactgatg gtgtaaggtg gcttctacgc tgacttgtac aatagtcaat ttacagaaga
    33361 tgaagcagaa gaataaatca aaagaaggct tgacggcctt ctttttctta tttatactag
    33421 tacacataga aagagagaag tatgagtcag aaattataca atatgaaatt tgctgctgtc
    33481 tatttagcct tgattgcaaa agttgagcga aagggtggag aggcagagtc agttcaccaa
    33541 gtgaccagtt ggttgacagg gtatgaagtg agtgacgttc ttgcttgtct ggatagggat
    33601 gttacttacg gagatttttt tcgacaagca ccatattatg tccctgaacg aattgcaatt
    33661 acagggaaga tttgcggtgt ccgtattgag gaaattgatg atcctctgat gcaggaaata
    33721 cgtcgcttgg acaagctagt ggattggctt gccaagggga aaacatctca acaagttcta
    33781 gaaaagtatg agaagcataa atgaaaaatt atcaagaatg gtatcgaaat atcagctcca
    33841 gactaactag tcgtccaatt cttttattcc tattacgcag tttcaatcgt ttgatgacag
    33901 tcgccatgcc cctggtctat ctgatcttgc tagtcaccac ttacctgcaa ctaggacttg
    33961 gtcagcaagt tggggtttat gtgtttatcc ctgctacagg ttttgtgatt ttatcccttc
    34021 ttcgtaagaa aatcaatgcc cctaggcctt atgaggaatg ggatattaaa cccttgcttg
    34081 acagagatag tcctggtcag tctatgccca gtcgtcatgt cttttcagca accattatct
    34141 ccatgacttg cttacatgct agtctaactg tgggctttat cttgttggtc ttgtcagccc
    34201 tcctcggtct cgtgagagtc ttaggtggtg tacattatcc caaggatgta gtagttggtt
    34261 atatttgtgg tcttgcgtgg ggtgtgcttt tctttctatt ttgacctgta agttaagttg
    34321 gtcttgcaac cacttactgc ttcaaattga ccacttgctt ttttgccctt gtattcctaa
    34381 cttagctttg atatagtaga gtcagaaagg agatgtgatg aagttacgaa ttgagattga
    34441 cggcaattta gaggagactg aaattgtcat caagaccccc actttgacag atgaaattgc
    34501 agacttgcaa cggctcttgc aagagtcaaa ggctccgagg ttgacttttt acaaggggac
    34561 aggtgaatat tatctagacc tgtcagaaat tctcttcttt gaaacagaag ggagcaagat
    34621 ctacgctcat aaccagaagg aagcttatga ggttcgcctc aagctctatg agttggagtc
    34681 tatcttgcct cgctatttta atcgagtttc caagtcaacg atcgcaaaca tccgtcagat
    34741 ttactcagtg gacaagtcct tttcaggaac gggcaccatt tccttttatc agacgcacaa
    34801 ggaggttcat gtctcacggc attaccaatc cctcctaaaa gaaaatctaa gaaacatgag
    34861 gtaaaaaaca tgaaaaagaa agcatttggt attgttttat tggttttagc agcttggatc
    34921 ttgctgcaag ggaattttgg aattccttct ttggatggta aaatatggcc tttactaggt
    34981 attgtttttt ttgcttataa gtccattgag tccatcctta gacgtcatct cacttcggca
    35041 gtttttacag gtttactggc gatcatcatt gcaaattacg cttatgactt gttaccagtt
    35101 accaatcatt ctcttatttg ggctagcatc ttggtggtac ttggtgttgg ttatctgacg
    35161 cattcaagta agttctggaa tgaaaaaaaa tggtggtaca atgggaaaaa aacagtcgtc
    35221 acggataagg aagtcgcttt tggtagcggg accttctata agcaagatca agatctcgta
    35281 gatgaccaag tggaagtcgc ttttggggat gctaaaatct actatgataa tgcagagatg
    35341 ctaggtgatt ttgcaacttt aaatattgaa gtggccttcg gaaatgcaac cgtctatgtt
    35401 ccacaacact ggcgtgtaga tttgaaagta gaaacctcct ttggtgcagc taaggctgac
    35461 gctcctgtag ccccaaccag caaaaccttg attatccgtg gagatgtggc ttttgggaag
    35521 ttggaaattg tctacgttaa ataaaaaaat cttcacttca accatcaaaa tagacgtact
    35581 aagagtagga aattgatgcc ttgctctgat ttcagttcta tggttgttag actttaaaaa
    35641 atgaaatgct gcctttaaaa gttgtatatt tttcgatatt ttggctttta cgtttgatgc
    35701 atctatgtcc tacagcgtag atgatgtagt gtcaaatgct tttaaaaaac gaatgatatt
    35761 ggacagtttt tttgccttta attgctcagg aaccatgaaa gtcagtactt gggtttatga
    35821 caagggagaa tggtattatg taagttcttc tggtgccatg attgcgaatg attgggtcaa
    35881 agacaatggc aagtagtatt atctggcttc atcaggtaag atgcttcgca atacctacac
    35941 acctgatggt tactacgttg gcaacttagg tgcctggcaa taagaataat actctttgaa
    36001 aatctcttca aaccacgtca acgtcgcctt atctacaacc tcaaaaccgt gttttgagca
    36061 gcctgcggct agctttctag tttgctctta gtataagaag tccttttcct taaaggaaga
    36121 ggctttttac ttgcttttct gctgcttcct catttgtcct gaagcctttt ttgtgttaaa
    36181 atgaatggta tgaaagctaa aaaaatgtgg atggcaggct tggctctgct aggtatcgga
    36241 agccttgctc ttgctacgaa aaaagttgca gatgaccgta agctcatgaa gactcaggaa
    36301 gagttgacag agattgtgcg agaccatttt tcagacatgg gggaaattgc gaccctctat
    36361 gttcaagtct atgaaagcag tctagagagc ttgcttggtg gcgtcatttt tgaggatggc
    36421 cgtcattata cctttgtcta tgaaaatgaa gacctagtct atgaggagga agtcttatga
    36481 tacagccagc aagtttagaa gaattagcat ctttagtgga aaaagcgggc aagaaggtct
    36541 tcctttttgt ggcagactgg tgtggcgatt gtcgttatat ttatcctgcc ttaccagaga
    36601 ttgaagagac caatccagag ttcaccttta ttcgaatgga ccgagatcag tatatggatt
    36661 tggccaaact ctgggatgtt tacggaattc ctagccttgt tgttctagaa aaggacaagg
    36721 aaatcggtcg ttttgtcaat cgcgaccgta aaagtaagga gcaaattaac gattttttag
    36781 caggattgaa ataggagaaa aaggaaacaa tgatttttac gtataacaaa gaacatgtcg
    36841 gtgatgtcct tatggtcatc gtgaaaaata gcggagatgc caaactgaat gtggaacgca
    36901 aaggcaaggt agcccgtgtt ttcctcaaag aaaatgggga aacagtagct tggaacattt
    36961 ttgaggtttc gagcttgttt gaaattgcag agcgcggtca agtcttttta tcagatgagc
    37021 aagtcgctcg tttgaaccaa gaattacagg cggaaggttt tacagaagaa attgttaatg
    37081 ataaggaacc taagtttgtt gttggtgaaa ttgtcgagat ggtagctcat ccagacagtg
    37141 accacctcaa catctgccaa gttgcagtcg caagtgacaa gatagtgcaa atcgttgcag
    37201 gagcacctaa tgcgcgtgtt gggttgaaaa ccattgtggc tcttcctggt gccatgatgc
    37261 caaaagggaa tttcattttc ccaggcgaac ttcgtggtga aaagagtttt gggatgatgt
    37321 gtagtcctcg tgaattgcat ttgccaaatg ctccgcaaaa acgtggggtg cttgaattat
    37381 cagaagacca agttgtcgga acaccgttcg acccagcgaa acactggact gcctaggaac
    37441 ttgtcagcat ctgatagaag gaaataagat ggcaaaaaat gtagtgatta cgggagcaac
    37501 ctcaggaatc ggtgaagcga ttgcgcgtgc ttatctggag cagggtgagg atgtcgttct
    37561 aacaggacga cggatagaca gattagaaat cctcaagtcg gagtttgcag taagctttcc
    37621 aaatcaaacc gtctggactt ttccactaga tgtgacggat atggtcatgg tgaagactgt
    37681 ttgctctgat attctagaaa cgatagggag gattgatatc ttggtcaaca acgccggact
    37741 ggctcttgac ttggctccct atcaagacta tgaggagttg gatatgttga ccatgttgga
    37801 taccaatgtt aaaggtctga tggcggttac tcgctgtttc ttgccagcaa tgataaaagt
    37861 caatcaaggt catattatca atatggggtc aaccgcagga atctacgcct atgctggtgc
    37921 cgctgtttac tcagctacca aggctgcggt taagaccttt tcggatggac tgcgaattga
    37981 taccatcgca acggatatca aggtgacaac cattcagcct gggattgtcg aaacagattt
    38041 ctcaactgtt cgttttcatg gtgataaaga gcgggctgcg tccgtttacc aaggaataga
    38101 agccttgcaa gctcaggata ttgcagacac agtagtctat gtgaccagtc agcctcgccg
    38161 tgttcagatt acagatatga ccattatggc caatcaacag gcgacaggtt tcatgattca
    38221 taaaaaataa gaaatttcct cgaaaagtta caaatttctg taactttttt tgatttccta
    38281 cgaatagata agtaggagga agaaaatatg tataataaa
//
LOCUS       DAVHKZ010000017        36635 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000017 DAVHKZ010000000
VERSION     DAVHKZ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36635
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.017"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..316)
                     /locus_tag="VVO74_001058"
     CDS             complement(<1..316)
                     /locus_tag="VVO74_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU5695089.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            673..1119
                     /gene="rplM"
                     /locus_tag="VVO74_001059"
     CDS             673..1119
                     /gene="rplM"
                     /locus_tag="VVO74_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU5695090.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            1139..1531
                     /gene="rpsI"
                     /locus_tag="VVO74_001060"
     CDS             1139..1531
                     /gene="rpsI"
                     /locus_tag="VVO74_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU5695091.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            1880..2089
                     /locus_tag="VVO74_001061"
                     /pseudo
     CDS             1880..2089
                     /locus_tag="VVO74_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2245..2583
                     /locus_tag="VVO74_001062"
     CDS             2245..2583
                     /locus_tag="VVO74_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEU5695092.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVKEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            2773..4209
                     /locus_tag="VVO74_001063"
     CDS             2773..4209
                     /locus_tag="VVO74_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU5695093.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            4261..4500
                     /locus_tag="VVO74_001064"
     CDS             4261..4500
                     /locus_tag="VVO74_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEU5695094.1"
                     /translation="MIGSIAAILTTFAFLPQVFRIVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            4630..4944
                     /locus_tag="VVO74_001065"
     CDS             4630..4944
                     /locus_tag="VVO74_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEU5695095.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            5062..7042
                     /locus_tag="VVO74_001066"
                     /pseudo
     CDS             5062..7042
                     /locus_tag="VVO74_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
     gene            7052..7366
                     /locus_tag="VVO74_001067"
     CDS             7052..7366
                     /locus_tag="VVO74_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEU5695096.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            7397..7903
                     /locus_tag="VVO74_001068"
     CDS             7397..7903
                     /locus_tag="VVO74_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695097.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LSQFISPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLALSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            7983..9329
                     /gene="celB"
                     /locus_tag="VVO74_001069"
     CDS             7983..9329
                     /gene="celB"
                     /locus_tag="VVO74_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEU5695098.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            9711..9887
                     /locus_tag="VVO74_001070"
     CDS             9711..9887
                     /locus_tag="VVO74_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695099.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            10288..12501
                     /locus_tag="VVO74_001071"
     CDS             10288..12501
                     /locus_tag="VVO74_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEU5695100.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNKNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQVAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GILDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLAFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTI
                     PVFAKSGAIIPLVGSEIDMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELTLQGDSSIVPSNRRHRIHFKGTNVSIIELPNKNDTARFECKDNKTISLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(12723..13199)
                     /locus_tag="VVO74_001072"
     CDS             complement(12723..13199)
                     /locus_tag="VVO74_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU5695101.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            13422..16625
                     /locus_tag="VVO74_001073"
     CDS             13422..16625
                     /locus_tag="VVO74_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEU5695102.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEVKKKYKLRFKIKTDNKIGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDTYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKSPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            17005..17390
                     /gene="tnpA"
                     /locus_tag="VVO74_001074"
                     /pseudo
     CDS             17005..17390
                     /gene="tnpA"
                     /locus_tag="VVO74_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(17769..18398)
                     /locus_tag="VVO74_001075"
     CDS             complement(17769..18398)
                     /locus_tag="VVO74_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU5695103.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKKEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSALSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDGISEIAQQYVTLR"
     gene            complement(18408..19409)
                     /locus_tag="VVO74_001076"
     CDS             complement(18408..19409)
                     /locus_tag="VVO74_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU5695104.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(19440..20081)
                     /locus_tag="VVO74_001077"
     CDS             complement(19440..20081)
                     /locus_tag="VVO74_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU5695105.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(20100..20915)
                     /locus_tag="VVO74_001078"
     CDS             complement(20100..20915)
                     /locus_tag="VVO74_001078"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU5695106.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            21187..21621
                     /locus_tag="VVO74_001079"
     CDS             21187..21621
                     /locus_tag="VVO74_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU5695107.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            21633..22823
                     /locus_tag="VVO74_001080"
     CDS             21633..22823
                     /locus_tag="VVO74_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEU5695108.1"
                     /translation="MIKKVTIEEIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELAHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            22834..23325
                     /locus_tag="VVO74_001081"
     CDS             22834..23325
                     /locus_tag="VVO74_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU5695109.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKNVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            23340..24119
                     /locus_tag="VVO74_001082"
     CDS             23340..24119
                     /locus_tag="VVO74_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU5695110.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            24106..24924
                     /locus_tag="VVO74_001083"
     CDS             24106..24924
                     /locus_tag="VVO74_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU5695111.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            24924..25217
                     /locus_tag="VVO74_001084"
     CDS             24924..25217
                     /locus_tag="VVO74_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU5695112.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            25239..27140
                     /locus_tag="VVO74_001085"
     CDS             25239..27140
                     /locus_tag="VVO74_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU5695113.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYLVEGDKSYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLNSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            27200..28201
                     /locus_tag="VVO74_001086"
     CDS             27200..28201
                     /locus_tag="VVO74_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU5695114.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(28311..28646)
                     /locus_tag="VVO74_001087"
     CDS             complement(28311..28646)
                     /locus_tag="VVO74_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695115.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(28657..28899)
                     /locus_tag="VVO74_001088"
     CDS             complement(28657..28899)
                     /locus_tag="VVO74_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695116.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(28915..29109)
                     /locus_tag="VVO74_001089"
     CDS             complement(28915..29109)
                     /locus_tag="VVO74_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5695117.1"
                     /translation="MNRVKEFRKELGISQLELAKNIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            29275..30225
                     /gene="rsmH"
                     /locus_tag="VVO74_001090"
     CDS             29275..30225
                     /gene="rsmH"
                     /locus_tag="VVO74_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU5695118.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DRKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            30237..30554
                     /gene="ftsL"
                     /locus_tag="VVO74_001091"
     CDS             30237..30554
                     /gene="ftsL"
                     /locus_tag="VVO74_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU5695119.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            30558..32810
                     /gene="pbpX"
                     /locus_tag="VVO74_001092"
     CDS             30558..32810
                     /gene="pbpX"
                     /locus_tag="VVO74_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEU5695120.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            32812..33792
                     /locus_tag="VVO74_001093"
     CDS             32812..33792
                     /locus_tag="VVO74_001093"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU5695121.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLFAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            34355..36460
                     /locus_tag="VVO74_001094"
     CDS             34355..36460
                     /locus_tag="VVO74_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU5695122.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMSQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFNILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGNFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
BASE COUNT        11582 a         6125 c         7870 g        11058 t
ORIGIN      
        1 aaaataggtc attttcttct gggaggagga tagtttctct accgtccatg tctaaaacca
       61 gtactcttgg gggataacga gggtcgaaag gatggttaaa gtcaaaatca atggctgtag
      121 ggaggtgttg acttgaaaag tggaaggtaa tctttccttg gttattaagc aattgaaact
      181 cgagttcttc ttccaattca aagacatttt ttaagaaatg gtcgataata taccaaaaag
      241 agtcaatgat gtcatcaggc aagctggtaa caatgccaaa actagcagac cgcatgtggg
      301 tattggtaaa agccatatct ctgtctcctt tcttttccct tatcatacag caaataggat
      361 taaaaatcaa gaaaaggtga ttttttgaaa aggattttaa ctacagggaa aaagaaggaa
      421 aaaaattccc aaaaatctac cgaagttaat aggtaaattc ccaaattaac ttgattatat
      481 aactttcagt tactttgaga agttaccgaa aaatattttt catatctatt gacttttagg
      541 ggtgaaattt ggtatgatag taggcggtat tgtttacccc atttgaaagg ccccggaacc
      601 ttccaaatac ttttcgatgg gaaggaacac ccatcaccgt aaacaaaaat cgaactatat
      661 ataggagaaa tcatgaacaa aacaacattt atggctaaac caggccaagt tgaacgtaaa
      721 tggtacgtag ttgacgcaac tgatgtacca cttggacgtc tttctgcagt agttgctagc
      781 gtacttcgcg gaaaaaacaa accaacattt acaccacaca ctgatacagg tgacttcgtg
      841 attgttatca atgctgaaaa agttaaattg actggtaaaa aagcaactga taaaatctac
      901 tacactcact caaaccaccc aggtggattg aaacaaatct ctgcaggtga acttcgttct
      961 aaaaatgcag tacgtttgat tgagaaatca gttaaaggta tgcttccaca caatacactt
     1021 ggacgcgctc aaggtatgaa gttgaaagta tttgttggag ctgagcacac tcatgctgca
     1081 caacaaccag aagttcttga catttcagga cttatctaag gaaaggaaca aataaagtat
     1141 gtcacaagca caatatgcag gtactggacg tcgtaaaaac gctgttgcac gcgttcgcct
     1201 tgttccagga actggtaaaa tcactgttaa caaaaaagat gttgaagagt acatcccaca
     1261 cgctgacctt cgtcttgtca tcaaccaacc attcgcagtt acttcaactg taggttcata
     1321 cgacgttttc gttaacgttg taggtggtgg atacgctggt caatcaggag ctatccgtca
     1381 cggtatcgct cgtgcccttc ttcaagtaga cccagacttc cgcgattcat tgaaacgcgc
     1441 aggacttctt acacgtgact cacgtaaagt tgaacgtaag aaaccaggtc ttaagaaagc
     1501 tcgtaaagca tcacaattta gtaaacgtta attcgaaaga attactatac ttatacagag
     1561 cacctttcgg ggtgttcttt ttttatactt tcttactaaa ttggtgcaat tgacacagtt
     1621 gttgcgactt tagtcgctta caaatgtggc tgcaacctga caaggtcagt tgcctcaaaa
     1681 cgttaatcaa tacgattata tcaatgtttc aaagcactca aaagtttacc ttatgggtgc
     1741 ttttttcgtg cttttttgaa aagtttacct tatttttata gtaatatgaa ataagaatag
     1801 gacaaatcga ggatagtcaa atcgaattct aacaatgttt tagaagtaga ggtgtactat
     1861 tctagtttca atctactata ttatggataa tgcaagattc catagaatgg ggaagctaga
     1921 actcttgtgt gaagagtttg ggtataaact tttacctctt cctccctact cacctgagta
     1981 caatcctatt gagaaaacat gggctcatat caaaaagcac ctcaaaaagg tattaccaag
     2041 ttgcaatacc ttttatgagg ctcttttgtc ctgctcttgt ttcaattgac tataaatcgc
     2101 tataagaaaa aatcatttta ttggtataaa gaagtgattg aaagtaatgg cgaaacgtta
     2161 gataattagt tcataaaaaa caagtttaga tcctcatcta aacttgtttt tttaaaattg
     2221 aaggatgatt ttggaggata taagatgaca ttgactattc atgtatatta taaaggtgat
     2281 ggagatagtg caataaagtt tgcaagagaa atgcttgata gtggccttgt taaagaaatt
     2341 agaaatcaaa aaggtaactt gaaatacgaa tattttttac caattgaaaa agagggaact
     2401 attctcctta ttgatcagtg gataaatcaa gaaactttag ataaacatta tcaatcaaag
     2461 acaatgcaga aaatcttaga tttaagaaaa aaatatcact tgcagatgca agttgaacgt
     2521 tatatagaag atgattctgg gatgccagaa agcgataagt cgtttataga cacagggaat
     2581 tagaattatt gtgagagttt ttgtagtttg aaagtattga aaatcgtaaa gatatcatta
     2641 cgagaataca agaagatatt gttctatttc cattaaaaat tacttctttc cttaacaata
     2701 aggaaaaaga atgcgttttc atcttttggt ttaaggttta taataagagt atcaaagtca
     2761 ggaggaaaaa agatgactac ttttaaagat ggatttttat ggggtggtgc tgttgctgct
     2821 catcaacttg aaggtggatg gcaagaaggt ggcaagggaa ttagtgttgc tgatgttatg
     2881 actgctggtc gtcatggagt agctcgtgaa attactttgg gagttttaga gggtaaatat
     2941 tatccaaatc atgaggcgat agatttttat catcgttata aagaagacat agcacttttt
     3001 gctgaaatgg gattcaagtg cttccgtacc tctattgcat ggacacgtat ctttccaaaa
     3061 ggtgatgagt tagagccgaa tgaagaagga ttacagtttt atgataatct ttttgatgaa
     3121 tgcttaaaga atggtattga acctgtcatc actctatctc attttgaaat gccttatcac
     3181 ttagtgaccg aatatggtgg ttggaaaaat aggaaattga ttgatttctt tgctcgtttt
     3241 gcagaagtcg tatttaaacg ttacaaagat aaggttaaat attggatgac tttcaatgaa
     3301 atcaataatc aagcgaatta tcaggaagat tttgcaccat ttactaactc aggtattgta
     3361 tatgaggaag gtgataatag agaagcaatt atgtatcaag cagcacatta cgaattagtt
     3421 gcttctgcac gagctgtaaa aattggtcat gagattaatc cagattttca aataggttgt
     3481 atgattgcga tgtgtccaat ttatccagtt acttgcaatc ctaaggatat cttaatggca
     3541 atgaaagcta tgcagaagcg ttattatttt gctgatgtgc atgttttagg taaatatcct
     3601 gagcatattt tcaagtattg ggaacgaaaa ggtatttcag ttgattttac tgaccaggat
     3661 aaagaagatt tacttggtgg gactgtagat tacattggtt tcagttacta tatgtccttt
     3721 gctatagact ctcatcgtga aaataatcct tattttgatt atcttgaaac agaagattta
     3781 gtgaaaaata attatgttaa ggcttctgaa tgggagtggc aaattgatcc agaaggttta
     3841 cgttatgcgt taaattggtt tacagaccac tatcacttac cactctttat tgttgaaaat
     3901 ggttttggag ctatagatca agttgcagca gatggtatgg tacatgatga ttatagaatt
     3961 gaatatctag gtgcccatat tcgtgaaatg aaaaaggctg tagttgaaga tggtgttgat
     4021 ttaatgggtt atactccatg gggatgtatt gatttggttt cagctggtac cggtgaaatg
     4081 cggaaacgtt atggttttat ttatgtagat aaagatgaca atgggaaggg aagttataat
     4141 cgttccccga aaaaatcttt tggctggtat aaggaagtta tttcatctaa cggtgaatca
     4201 gtagaatagt ataaacaaac tgagattatt ctcagtttgt ttagcatatt gggatgacat
     4261 atgattggaa gtattgcagc aattttaaca acatttgcat ttttaccaca agtttttcgt
     4321 atagttaaga caaaggacac aggatctatt gctctaggta tgtatgttat gcaagttatt
     4381 ggtattgcat tgtggcttgc tcatggtatt cgtataggag acttgccttt gattttagca
     4441 aatagtgttt catttctact ctcaggaata attttatttt ataaattgaa gtataaataa
     4501 tttttttcca tatcatttag gaaaatgagg gaattgtcat tggaaacgct ttattttata
     4561 ataaaaatag ataacaaata agccaactta gcacagcttt gattggattt aagaaaagga
     4621 gaaaatatta tggcaaaagc tttaattatt tgtgcagcag gaatgtcttc atcacttatg
     4681 gcacagaaaa caacagagtt tctaaaagga aaagggaaag atattgtagt tgatgctatt
     4741 agtgctactg aaggagggaa agctatcgca gcagcagctt ttgatttgta tcttgtcagc
     4801 cctcaaacaa aaatgtactt taagcaattt gaagaggctg gttctaaagc aggaaaacca
     4861 gttgtacaaa tacctcctca agcctatatt cctattccaa tgggaattga aaaaatggct
     4921 aatttgattc ttgagaatat ttgatgaaca catgaaatgt caataaatat ttaggttaag
     4981 ataaattgtt ttgagtttga tataaactga tttaagtgta taatatgctt caatatatga
     5041 aaacatacgt tttaggaggg aatgaatgtg ttaaacatta aagagaaaga tatccttcaa
     5101 tttttaataa aaaataagga acgttttgtt acaagcaaag aactggcaga atatttatcc
     5161 tgttcagata gaactgtccg taatgtactg aaattaattg agaagacaat gattattcaa
     5221 ggagtccggt tgatttcaaa acaaggtcaa gggtatcaaa tattttttga gaatcaaggc
     5281 gcttaccagg agtttagaca aacttatgaa ctggaagaag actatacgaa aactgcggtt
     5341 tcaaaaggtg atgatcgttt agtatttatc ttaaataaat tattatttga gcaagttcca
     5401 gttctttttg atgatttagc tgatgaactt tacgttagcc gttcaacatt atctcatgat
     5461 ttcagaaaga tacgagtgat gttatcagag tataatttgt ccattgagag tagggcgaat
     5521 aaaggagttt atgtctcagg cgaggaacgt gataaacgac gttttatcat aaattatttc
     5581 ctagagaatc aattttttaa aacaatacat tgctatgtaa aatttaactt ttttgatcaa
     5641 actgttccat tagaagaatt tgctagaatt gttttggatg aatgccaaga ggccaaccta
     5701 aaactatctg attttgtact acagaattta gtagttcaca tagcattgtc tgtgattcgt
     5761 ttaaaatccg gatttgaaat aaaaaatata gactgtcaga tgactgatga tgcaatagag
     5821 agaaaggttg cccaaagaat tctttctaaa gtaagagaag taacaaatca ggaatttcca
     5881 gttcaggaaa tagactacat tactttgcat ttgttagcta agagtcaaca atgtcaaaaa
     5941 aatcagaaga atatttctga agaagtttta aaaaaaatct ttatttaaaa catttcagaa
     6001 tttaggatta gatgatatgt ataacttttc ttcagatttc caactaattg aaggattgat
     6061 aactcatcta atgacactac aagtacgttt agaaagccgg attaccttaa ataacccttt
     6121 ggtagatgaa attaaacaga attatagtga tatattcttt atgactagag aaattcttgc
     6181 aaatatggac aagttcttgg agtggacaat atcagatgat gaagtagcat atgtaagtct
     6241 tcacttttta gctgctatgg aacgtagcaa agagagtact aagtttaata ttcttgctat
     6301 ttgtgcaaca ggatttggtg cagcccaaat gttaagaaat cgtttggaaa cggagtttgg
     6361 gaagcgagta gaagttgttg atgtaatagg ctactatgaa ttgaatcaag aaaaacttaa
     6421 aggaatagat tttatagtgt cagctgttga tttatcaaat ctatattttc aaatcccagt
     6481 ttttaaagtt agtgtgtttc ttaaaagtga tgagatggaa atgattagaa aagctatgga
     6541 tcagatgcaa gtttctagtt atgtacaatc atcaaagatt aacaaatttg aaaacaacgg
     6601 ctttagacag tattttagta aagaaaattt tttaatatgt actgaatcag acaaggtaaa
     6661 tttacttgaa aagatggttg agggtttatc tgttggtgaa tcaaatgagt ttgaacaatc
     6721 tttactttat ggaattaaac agcgcgaaga attaagttca gttgtttttt ctgaaaaaat
     6781 tgcagttccg catcctattc agccctttgg tacagaggga aaggtttcgg ttgcaatttg
     6841 taaagattcg ctactctggg ataatcaaag ttcacatgtc cagctagtat ttcttctatc
     6901 tccatcaata tatgggaacg aaggtttggc aactgtgact aaaaagatag tctctctgac
     6961 agagaatgat gaattgcaaa atcagctaat atcttgcaat aactttgaag attttattaa
     7021 catatttgag aagataaaat aggaggttca tatgaatcaa gaggaactgc aggttgcagc
     7081 atttgaaatt atcctgcatt cgggaaatgc aaggtcagaa atacatgaag catttgcaaa
     7141 aatgagagaa ggtagttttg atgatgcaga aagtaaatta aatcaatcaa atgagataat
     7201 tcttgaagcg catcatgcac aaaccaaact cttgcaagaa tacgcaagtg gagtggaaat
     7261 taaaattgaa attatcatgg tacatgctca agatcattta atgaccacta tgacattatt
     7321 agaagtagca aaggaaatgt tagctcttta taagaaagtt aactaaatat gtgttgttat
     7381 ataaggagga aatgatatgg ataaaaaaga acgacaaaag attgaacaac aacgtcgaga
     7441 gatggctcta actaatactt tttttaatcg atatcttctt ctacgttatt caatagcact
     7501 cttctttttt gggaatattt attggctttt gagtcagttt attagtccct cgcctattat
     7561 tattttcccc attatgctca tagtattttc tattttagca actgttgaac aatttaaact
     7621 ctatggaaat aggaaagaaa agttgggaat aacactaatg tttgttagaa tacaaatgct
     7681 tatttcaata ggattacttg ttttaacttg gacaagttgg tttaagaatc tttttccgat
     7741 ttttgaaaat aaccaagtag cacgtttatt tgtttttgta gttcttctat taggtttagc
     7801 tctgagtttg ttagacatta gaagaattaa aaaaatttat aaacgaacag ataaggctta
     7861 tcaacaattt gtccaattgg aaaagaactc acttagttta taatcctgat ctagtataat
     7921 ttgtatttga aaccagtctt tagaaagtaa aaattattat gttttattaa ggaggtctat
     7981 ttatggatca acaaaacggg ttgtttggtt ttcttgaaaa ccatgttatg ggaccaatgg
     8041 gcaaacttgc tcagtttaaa gtagtgcgtg ctatcacggc tgcaggtatg gctgctgtac
     8101 catttactat tgtaggatca atgtttttgg tattcagtat tttgccacaa gctttctcat
     8161 tttggccaat tgtggcagat attttctctg cttcatttga taaattcaca tcactttaca
     8221 tggttgcaaa ctatgcgact atgggttctc tatctcttta tttcgttcta tcacttgcat
     8281 atgaattgac aaaaatttat gcagaggaag aagaactcaa tatgaatcct cttaatggtg
     8341 ccttgcttgc cttgatggct tttgtcatga cagtaccgca aatcattttt gatggtggaa
     8401 tgatgaagac tgtgacaagt ctaaaagaag gtgcagtaat tgcagatgga tgggcaatgg
     8461 gaaatggagt cgcacgtttt gggacaacag ggatttttac cgcaatcatt atggcaattg
     8521 tgactgttct tatttatcgt atgtgtgtta aacataattg ggttattaaa atgcctgaag
     8581 ctgttccaga aggagtttct cgtggattta ccgctttggt tccgggattt gttgttgcat
     8641 ttgttgttat ctttatcaac ggtcttcttg tagcaatggg aacagatatt tttaaagtca
     8701 ttgcaattcc atttggtttt gtatccaatc tgactaattc gtggattggt ttaatgatta
     8761 tttatctatt gactcaacta ctttggattg taggtatcca cggtgcgaac attgtttttg
     8821 catttgttag tccaattgct cttgctaaca tggctgaaaa tgctgctggc gggcacttcg
     8881 ctgttgcagg tgaattttct aatatgtttg taattgcagg tggttctggt gcaactttag
     8941 gactatgttt atatattgct tttgcctcta aatctgaaca gcttaaagca ataggacgag
     9001 catctgtagt tccagcctta tttaatatta atgaaccatt aatttttgga ttacctatta
     9061 tctataatcc agccttggct ataccattta ttttagcacc aatggttact gctactattt
     9121 attacgtagc gaattctcta aactttatta agccaattat cgcacaggtt ccatggccaa
     9181 ctccagtagg gattggagct ttcttaggga cagcagatct tcgagctgta ttagttgctc
     9241 tagtatgtgc atttgcagca ttcctagtct atcttccatt catccgtgta tatgatcaaa
     9301 aattggtgaa agaagagcaa ggtatctaat aagtaaaaaa gtatactcga tgatagaatc
     9361 catatagttt aaataatgag tgttaacatt agcagtgaag agatcttttt aagatattct
     9421 tctctgcttt ttcattttat ttttttgcta tgtagggtat gaagcaaaat agaaagtagt
     9481 tcgaatagtt gataaacagg gaactgctgt tatttaaaaa aacaataaag taaagtatgt
     9541 tatcgtagaa tacgatacaa tagtaaaaaa gcaaaaagaa tgcgttttat atttgggttt
     9601 gaggcttata aaataggata agcgtgctga aaacttagat atgacaaaca aaataaaatt
     9661 tttaaaagct acagagaaac atggtataat gtatctaaag gaggtagcat atgtccttag
     9721 atatagataa agaaaagatg acaatcatgg gaatagcttt tgaaaaccga tccgttttta
     9781 agagtgtttg gtatgcttta agtacaaata tgattgaagg atggcgacct acggttagtg
     9841 atgttgaaaa attacgagat gaagctcttg ctctggggat gacttaatga agcgcaactg
     9901 ttatgaatct tatgactatg ttgatccgga taatttatat accgatccgg gttcttcagt
     9961 tctaagaaat aagcaggaag gaaaaaagca cgtgagcttg aatatcgtat gattgctagt
    10021 aagagtttga aattatttat caatcctatc ttagttaata gtttaaaagt agtttgtttc
    10081 acaactgcat aagcttagaa aagttgaaaa gtgataactc tttaataaac tcttggtttg
    10141 ttaaaagata ttttgtccac tacatttttt caattgacta ttatttgtca tagatataac
    10201 agatagaaca ttgcattcag aataatgaaa aacgcatcaa aaatggtgcg ttctgttttt
    10261 atgctaccat aaaaggagga aaacaaattg aaaattttta agggagagtt ttatcgaatc
    10321 tctgtattaa cagacaagct agtaaggtta gaatactctc gaactggaaa ttttgaggat
    10381 agaacgacac aacttatcta taatagagat tttggccaag tttcgttaga ttatatcgag
    10441 acatcaaatg tactagatat tatgacggac tattttcatc tgcactttaa taaaggagaa
    10501 tttaacgccg aaaatttatt tatagaatta aaaggaaatt ttgccgtata tggtagtcgc
    10561 tggtattttg gtgaatctat tgaaacgtta aaaggaacag ctcggactct ggataaggca
    10621 gatggagcaa tctcgttaga agatggaatt attagccgaa atggtatagc cttattggat
    10681 gattctcaag gatttatttg ggatgaacaa tctggttata ttgagagaga aaatcaaatt
    10741 gacctgtatt tctttgccta tgggcatgat tatagaggag caatcagaga cttttaccat
    10801 ttgactggtt caacaccctt gttgccaaga tatgctttag gcaattggtg gagtagatat
    10861 tggccttata cgtcggatga atacttggat ttaatagaca gatttgaaac agagaaaatt
    10921 ccattatcta tcggtgtgtt agatatggat tggcatataa ctgacattcc agctcgtttt
    10981 ggaagtggct ggacaggata tagttggaat aaaaacttaa tacctaatcc agaacagtta
    11041 ttgcaacaac ttcatgatag aaagttaaaa ctctctttaa atgtccatcc tgctgatggt
    11101 atacgggctt atgaagaagc ttatcctcaa gtcgccaaac gattagggtt aaatgtagaa
    11161 ctagaagaac ctgccatttt tgattttttt aatccctctt ttagggaagc ctactttaaa
    11221 gatgttcatt atgagctaga aaagcaggga gtagattttt ggtggattga ctggcaacaa
    11281 gggactcaag gcatattgga tccactatgg cttttaaacc attatcatta tcaggatagt
    11341 tgtaaaaatg cagaaggtgg tttgatttta tcaagatatg caggtcctgg tagccaccgc
    11401 taccctgttg gtttttcagg ggacactatt attagttgga attccttaag atttcaacct
    11461 tattttacag cgacagcatc taatatcggt tatagttggt ggagccatga tatcggtggg
    11521 cacatgctgg gggattatga cgaagagctg caaactagat ggctacagtt tggtgttttt
    11581 agtccgatca ctcgattaca tagttctaga agtcctttta atagtaaaga accttggttt
    11641 ttttcagaaa caacatctaa gattatgaag aaataccttc gtttgagaca tcagatgatt
    11701 ccctatctat ataccatgaa tgtaaagaca cacgaggaag gtgccccatt aatcagtcca
    11761 atctattatt tctacccaga gaatgatgag agctataatg ttccaaacca atactttttt
    11821 ggaacagaac taatggtggc tcccattgta gaaaagatgg acttggcatt ccaatctgca
    11881 aaagtggatg tatggttccc tgaaggtgaa tggtatgact tcttttcaga gaaaaaatat
    11941 acaggtggtg tgaagttgag tgtttataga gacatttcga ctatacctgt gtttgcaaaa
    12001 agtggtgcga tcattccctt ggttggttct gagatagata tgggtgttga tttacctgaa
    12061 gttgtagatt ggtatgtatt cccaggcaaa caacattctt ttgaaatgct tgaagatcaa
    12121 aatggtcaaa gatataaaac aagattatca atcgattggg aaatggggat ggtagagtta
    12181 acattacaag gagattctag tatcgttcca agcaatagaa ggcatagaat tcattttaaa
    12241 ggaacgaatg tgtctataat tgaattacca aataagaatg atacagctag atttgaatgt
    12301 aaagataata aaacaatatc tttaaatgat gaagttttta gactactaaa gacagcttct
    12361 cttccatatg aattaaaaga tagattgtta aatcaattca tcaatgcgaa aaactctcat
    12421 gacttaatga atatcttgca tcatcaggat aaggaattga gagggcgttt gttggaaatg
    12481 atatttacta gccaaaacta attgatataa ttagaaagtc atttgtttag tgtatatgaa
    12541 gattctgtat ggtattcgtt atcactggtc acattgaaaa tgtgaaataa gcacctacaa
    12601 catagacttt acaacacttc atgtttcata tcatggggtg tttttctatt taagtcaaag
    12661 ccaatcaaaa aatctcacta ttcatcaggt taaaggaaac ctaatcatag tgagattgtg
    12721 aattatagta gagtttgtat cgcctcttca atttgttttg ggtctgtttt tgaagaaaag
    12781 cgttcaaaga cttgcccatc tcgaccgatg agaaacttag cgaaattcca ttcgactcgt
    12841 tttcctagtg ggccggattt ctggtctttt aaccagacat agagagggtc tgcttcctta
    12901 ccgttgacct taatcttggc aaaacgtggg aaggtggttt gaaaatgtag gctacagaag
    12961 gcgttgattt cctctgcgct gccgggtgct tgtcccataa actgattgca agggaaatcc
    13021 aatatttcaa agccctgatc ttgatagcgt tcatagagtt cttgaagtcc ctggtactgg
    13081 ggcgttaaac cacatccagt agcagtgttg acaatcaaga gaactttgcc acgatagcta
    13141 tccaagggag ttgcttggtt gttttggttc aaaacggaaa aatcataaag tgaagtcatg
    13201 agggcctctt ttctttttct acattgtaac agtttttact tttttcgtcg agtcggatgg
    13261 aagatattgt tgaagaataa gccctcaata tgatagaaac cgtttacaaa taactttaaa
    13321 aatggtataa tttaattaaa ccggtttact tagttgctat aaatctctaa tttgagattt
    13381 agttcctatt gattttacaa tatgtttatt ggagtgtata catgcaaaca aaaacaaaga
    13441 agctcattgt gagtttgtct tcacttgttt tatcaggatt tttattaaac cattatatga
    13501 cagttggagc ggaagaaacg actacgaata ccattcagca aagccagaag gaagttcagt
    13561 atcagcaaag ggatacaaaa aatttagttg aaaatggtga ttttggtcag acggaggacg
    13621 gaagcagtcc gtggacagga agcaaagctc aggggtggtc agcttgggta gaccagaaga
    13681 atagttctgc agatgcctca actcgagtca ttgaggctaa ggatggggct atcactatct
    13741 caagccatga gaaattaagg gcagcgcttc accgtatggt tcctattgaa gttaagaaaa
    13801 agtataaact gcgtttcaag attaaaacag ataataaaat cgggattgcc aaagttcgta
    13861 tcattgagga aagtggtaag gacaagcgat tgtggaattc tgcaacgacg tcaggaacaa
    13921 aggactggca gaccattgaa gcagactata gcccgacttt agatgttgat aaaatcaagc
    13981 tggagttatt ctatgaaaca ggaactggga ctgtttcctt taaggatatt gagctggtag
    14041 aggtagcagc ccagctttct gaggattctc aaacagataa acagcttgag gaaaagattg
    14101 atttaccaat tggaaaaaaa catgtttttt ctcttgcgga ctatacttat aaggtagaaa
    14161 atcctgacgt tgcttcagtc aaaaatggaa ttttagaacc tcttaaggaa gggacaacca
    14221 atgtcattgt cagtaaagat ggcaaggaag tgaaaaagat tcctttgaag attctagcct
    14281 ctgttaagga tacatacaca gaccgtttgg atgactggaa tggcatcatc gctgggaatc
    14341 aatactatga ttctaaaaat gaacagatgg ccaaattaaa ccaggaattg gaaggaaagg
    14401 tagctgatag cctatccagt atttcaagtc aggcggaccg cacctatttg tgggaaaaat
    14461 tttcaaatta taaaacgtct gcaaatctga ctgccactta tcggaaattg gaggagatgg
    14521 ccaagcaagt gaccaatcct tcttctcgtt attatcaaga tgaaactgtc gttcgaacag
    14581 tcagggattc catggaatgg atgcataaac atgtctacaa tagtgaaaag agcattgttg
    14641 ggaactggtg ggattatgaa atcggtacac ctcgtgccat caacaatacc ttgtctctga
    14701 tgaaagaata cttctctgat gaggaaatta aaaaatatac agatgtgatt gaaaaatttg
    14761 taccagatcc cgaacatttc cgaaagacga ctgataaccc atttaaggct ctaggtggaa
    14821 acttagttga tatgggaaga gtaaaagtaa tagctggttt actgcgtaag gatgatcaag
    14881 aaatttcttc taccattcgc tcgattgagc aagtgttcaa gttggtagac caaggtgaag
    14941 gtttttatca agatggatcc tatatcgacc acaccaatgt tgcctatacg ggtgcttatg
    15001 ggaatgtttt gattgatggc ctgtctcaac tgttgccagt cattcaaaag accaagagtc
    15061 caatcgataa agataaaatg caaaccatgt accactggat tgataaatcg tttgctcctt
    15121 tgctggtgaa tggagagctg atggatatga gtcgtggacg ctcgatcagt cgtgcaaata
    15181 gcgaggggca cgtggccgca gtagaagtac taagagggat tcaccgaata gcggatatgt
    15241 ctgaaggaga aaccaaacaa cgtttgcaga gtcttgtgaa gaccattgtt caatcggata
    15301 gttattatga tgtctttaag aatttgaaga cttataagga tatcagtttg atgcaatcct
    15361 tgttaagtga tgcaggagtc gcaagtgttc caagaacaag ttacctatct gcctttaaca
    15421 agatggataa aacagccatg tacaatgcag agaaagggtt tggatttggc ttgtcactct
    15481 tttccagtcg taccttgaat tacgaacaca tgaacaagga aaataaacgt ggttggtata
    15541 cgagtgatgg gatgttctat ctttacaatg gcgatttgag tcactatagc gatggctact
    15601 ggccaacagt taatccatat aagatgcctg gtacaacaga gacggatgct aagagagcgg
    15661 atagcgatac aggtaaagtt ttaccgtctg ctttcgttgg aacgagcaaa ctagatgatg
    15721 ccaatgcgac agcaaccatg gatttcacca actggaatca aacattgact gctcataaga
    15781 gctggtttat gctaaaggat aagattgcct ttttaggaag caatatccaa aacacttcaa
    15841 cagatactgc tgcaactaca attgaccaga gaaaactgga atcaagtaat ccatataaag
    15901 tctatgtcaa tgataaagaa gcctccctta cagaacaaga aaaggattat cctgaaaccc
    15961 aaagtgtctt tttagaatcg tccgattcga aaaagaatat tggttacttt ttctttaaga
    16021 agagttcaat cagtatgagt aaggctttgc aaaagggagc ctggaaggat atcaatgaag
    16081 gacagtcaga caaggaagtt gaaaatgaat ttcttactat tagtcaggct cataagcaaa
    16141 atggagattc ttatggctat atgctcattc ctaacgtgga tcgtgccacc ttcaatcaaa
    16201 tgataaaaga gttagaaagt agcctcatcg aaaataacga aacccttcag tctgtttatg
    16261 atgccaaaca aggagtttgg ggcattgtga aatatgatga ttctgtctct actatttcca
    16321 accaattcca agttttgaaa cgtggagtct ataccattcg aaaagaaggg gatgaatata
    16381 agattgccta ctataatcct gaaacccagg aatcagctcc agatcaggaa gtctttaaaa
    16441 agctagagca agcagctcag ccacaagtac agaattcaaa agaaaaggaa aaatctgaag
    16501 aagaaaagaa ccattcggat caaaagaatc tccctcagac aggagaaggt cagtcaatct
    16561 tggcaagtct agggttcttg ctacttgggg cgttttattt attccgtaga ggaaagaaca
    16621 actaatttgt tcatcatcta gatgaattac atgaaactgt ggaaaataga aaaaatccga
    16681 agaaggccaa atatcttcgg atttttcttt taaaaaggga taagttgata cttatccttt
    16741 tttacttcat tatgtgacta tagcgttttg aaactagaat aggacgtcat aactgctaaa
    16801 agatttctat aaattcattt gattttccta atcaatttgt tcgtatccta tttcactcca
    16861 ctatattagt ccgtctcgct ccgtgaggtg cgagacaaaa caaccacccg ctatgcgggt
    16921 gcgcgtcgaa ggctatacca aaaaactcca aacgcgatac aataaaggtg ttcaatccaa
    16981 ttgtaaagcg aaaggagaaa aaatatggca caaaagactc atagtttatc atacacaaag
    17041 tggatgtgtt ctatcatatt gtgttcaccc ctaagtatag acgaaaagtc atctataatc
    17101 aatatagaag tagtttaggc gaaatatttc atcgcttgtg tagttataaa ggtgttgaaa
    17161 tgatcgaggg tcacttaatg ccagaccatg tacacatgtt agtcagtatt ccactaaggc
    17221 taagtgtttc gagtttcatg gggtatttaa aaggcaaaag tgcactcatg atgtttgaca
    17281 aacacgccaa tctcaagtac aagtttggga atcggcattt ctgggcggaa ggttattatg
    17341 taagtacagt agggcttaat aaagccacac ttaagaaata tagtcaagat taaagaaatt
    17401 atcgagtgga tgatttcttc acgagtatga aaatttgaga acgagtaaag tatgatatat
    17461 agtaaaatga aataagaaca ggacaaaatc gatcaggaca gtcaaatcga tttttaacaa
    17521 tgttttagaa gtagaggtgt actattccag tttcaatcta ctatagcact agataaattg
    17581 agtgtaaaag aatatgagga tccctttagg gatagtggta agtaatacca aagtctctta
    17641 aagaggcaag tgacgagtca agagcaataa ggcttgaaca acgtgaaagc cagcgtcttt
    17701 aggcgctggc tgatgatttg ggcttatagc tctgagataa accacccgtt agacgggtag
    17761 ttatgatttt atctgagtgt aacatactgt tgggcaatct cgctgatgcc gtcaaagttg
    17821 ccttgggaag cgagtttatt gagttcgcca ccaattccaa cggcatctgc accagcagcg
    17881 aaccattgag ggatgttgtt tagaccgact cctccggtta ccattacgga aacttgtggg
    17941 atcggtgcct tgactgcaga gatatatgct ggactgagag cactacctgg gaagagtttg
    18001 atgatttcac taccggcttc aagtgcagtc gtgatctctg tgagggtaat acagcctgga
    18061 atgtacggtg tgctgtagag attgcacatt ttcgcagttt cagcatggaa agatggagaa
    18121 acaacgtaat ttgctccggc tagaatggca tctctagcag ttacggcatc aagcacagta
    18181 cctgcaccga tacaaacact ctgatcgtcc tgatacaagt ctacaagttc cttgatgatt
    18241 tgtcctgcat actgattggt ataggcgatt tcaatagctt tgataccgcc cttgatacaa
    18301 gcaatcgagg cttgcagtcc ttctttcttt gtatttcctc gaatgacagc gacaattttc
    18361 tgttttttta gttcaataat cgtatctgat ttggtcatgt aattctccta acgaatgata
    18421 tcttgtgcat ttgccagtaa attttcaata ctagttgcgg aagtggagag atggtctcct
    18481 ggaagagtgc atttgagagt tgcgctcgca actgcaaagt caatggtagt ttttagggag
    18541 gaatgatgga gtagttggta aagggcacca gatataaagg catccccgct accaattcgt
    18601 tgatagactg cagtttttag ttggacagac tcttcaaatc gttcttccag agcataggct
    18661 tgatagacat ttttgtcttg ctcatcacta gagcggaggg tatggaaaat ggccttgaaa
    18721 ccataggctt cttttaaaag tcgcatgcga ttttccacct cttctaggct agcactgtct
    18781 cttggaaaca tctctagatt ttggtcatca atcatgagag gatcaatacc gaagcaatag
    18841 tcagtaaaac gtgcaaactt agaaaattca tacttggctt ctaggactga aatcatcttt
    18901 gttctcagat tgagatccat tgaaacgaca attcctcggc gcttggcttc ttccaagagt
    18961 aggagaagga tcgcacggac ctcttgaccg atagctatgg tgattccact aaaatgaaaa
    19021 tggctaatcc cctgaaagag agaatccata tctagcatgt ttggccgaat ctggctgata
    19081 ctcgtatgct tacgatcgta gaaaacttca ctttgacgac aaccaaagcc gttctccaaa
    19141 tagtagaggc cgattcgatc gccaagccga cagattgaac tggtatcgat ttggtgctgt
    19201 ttcaagaatg tgagaaaacg atctccaatc tcgttggcag ggagtgcggt aaagactttc
    19261 gttgagatac ccagggcttg caaattacaa gcgatgttaa tttctgatcc gccaaaataa
    19321 gtcgaactgg caacatgatc gccgatactg gtggcatcta atggtgagat tcgaattaat
    19381 ggttcgccaa acagtaatat tttcgtcatc cattagttcc tttctggttt agaatagctt
    19441 tacttggcta atacttcttt caaataagca gcgacttcat catcttggca gttttcaaag
    19501 aagtattctt ggaagtattt gccagagatg gtgtctttga ggaagtcttg gtcgattgtt
    19561 ttaaggatgg tcatcaaatc attgtgggtg atttgtttca cctcgtttaa gatacgagcg
    19621 ttacgttgtt cagggattac acgttctctt gggtagccac cgcccatttc ttcagcaaat
    19681 aagcgttcaa acatcaattt gagggtcagt tctgcccccc agccaaatcc tttggcataa
    19741 gggatagaca aggcgttacc accattgatt tgagaataaa ggtaagcgtc agttgggtcc
    19801 actgctagac cacagacaac accagggaag ctgtttaaag caagcatagc ccctacaccc
    19861 gtaccacagc cggtaacaac aaagtcaact gcctttgtat ttaaaaggat ggcagccatt
    19921 agtccgttct gcacataagt taattgactt tctccttctt ctccacgcat accatagtta
    19981 aataattggt agtctttttt atctgtcgct tcttttagac tatcgtaaat aatgtgattc
    20041 ttgctagctt gactattttc attgattaat gcgattttca taagatcttc tttctatttt
    20101 tactcaggtt gttttccgat gtaggctaag ataccgccat ctacatatag gatgtggcca
    20161 ttgacaaaat tgctggcatc actagcgaga aagacagcag ggcccatcaa atcttcagga
    20221 tttccccaac gtgcagcagg tgtttttgca atgatgaact ggtcaaatgg gtggcgagaa
    20281 ccatcttctt gcaactcacg aagaggtgct gtttgaggag tggcaatata acccggtcca
    20341 attccgttac attggatatt ggctccaccg tattcagacg caatgttgcg ggtcaacatt
    20401 ttcaagcccc ctttagcagc agcataagcg ctaactgttt cacgtcccag ttcgctcatc
    20461 atcgaacaaa tattgataat ctttccatgc cctttcttta tcatagaagg aataactgcc
    20521 tttgaaacga taaatggtgc gtttaagtca atatcgatga ccttacggaa atcagcggcg
    20581 ctcatttcgc acattggaac tcggcggata ataccagcgt tattaacgag gatgtcaatg
    20641 acaccaacct cttgttcgat ttgcttgacc atggcttgga taccgtcctc gtctgtcacg
    20701 tcacagacat atccatgggc ttcgatgcca acttcacgat aagcttcaat ccctttattg
    20761 accagatctt gattgatatc gttaaagaca atagtagcgc cggcttcagc gtaggatttg
    20821 gcaatagcaa atccaattcc ataagaagcg ccggtgatga gagcaatttt tccttttaaa
    20881 gaaaactgct caattgagaa tgatgtattt gtcatttgat acttcctttc aaatttgtta
    20941 agacttctct ataaccaaat tatattctag taaaccggtt ttgtcaataa ataaatattt
    21001 ttatttataa aaagatttat tttcctaaaa aaacggaaga ttttgaaatt tctgtctatt
    21061 aaaatggtta aaaagataat gaaagcgcta atattttttt aaaaaaacta ttgacaagat
    21121 aaaaataaag gattacaatg gggaatataa agtaaaccgg taaacctaaa caagaaagga
    21181 gaaaagatga aaattgtact tgtagggcat ggacattttg ctacagggat ttatagttct
    21241 ttacaattga ttgcaggtaa tcaagaaaat gtggaggcga ttgactttgt ggaaggaatg
    21301 tcagcagatg aactcaagca aaaaatctta cttgcaattt caaatgaaga agaagtttta
    21361 atcctaagtg atctcttggg aggatcgcca ttcaaggttt cttctaccat aatgggagaa
    21421 aatccagcca aaacaatgaa tgttctctcg ggtttgaact tagccatgtt aatggaagca
    21481 gtttttgcta gaatggctca tagctttgat gaggttgtta ataaatcagt agtggcggcc
    21541 cagggcggag tcgtaaatgg taaagaattg ttttcaacgg atgcagagga agaggaagaa
    21601 gatttcgaat cgggtattta aagggtgaaa gaatgataaa aaaggttacg attgaagaaa
    21661 taaaatcgcc tgagcgcttc ttagaagtac cacttctgac gaaagaagaa gtcggccagg
    21721 caatcgataa ggttattcgg cagttagaac tcaaccttga ctatttcaag gaagatttcc
    21781 cgacgccagc tacctttgat aatgtctatc caatcatgga taacacggaa tggaccaatg
    21841 gtttctggac aggagaactg tggttggctt atgaatacag tcaacaggat gcatttaaaa
    21901 acatcgctca taaaaatgtt ctttctttcc tggatcgtgt caataagaga gtagaattgg
    21961 ctcaccatga tctcggcttc ttgtacacac cgtcttgtat ggctgaatat aagataaatg
    22021 gagatggaga ggctagagaa gcagccttga aagctgcaga taagttgatt gaacgctatc
    22081 aagaaaaagg tggttttatt caagcttggg gagacttggg caagaaagag cattaccgtt
    22141 tgattatcga ttgcttgctc aatatccaac tcttattctt tgcttatcaa gaaacaggcg
    22201 atcaaaaata ctacgatatt gcagaaagcc atttctatgc ttcagctaat aatgtaatcc
    22261 gtgatgacgc ttcgtccttc cacaccttct attttgatcc tgagacaggt caacccttta
    22321 aaggtgtaac gagacaaggg tatagtgatg attcatgctg ggcacgtggt cagtcatggg
    22381 gagtttatgg tattcctttg acttatcgtc acttaaaaga cgagtcctgc tttgacttgt
    22441 ttaagggtgt gaccaattat ttcttgaatc gtctgccaaa agatcatgtg tcctattggg
    22501 atttgatttt taatgatggt agtgatcaat cacgagattc ttcagcaaca gctatcgccg
    22561 tctgtgggat tcatgaaatg ctaaaacatc tcccagaggt ggatgctgac aaagatattt
    22621 ataaacatgc tatgcatgcc atgcttcgtt ccttgatcga acattatgca aatgatcaat
    22681 ttacccctgg tgggacaagt ctcctccacg gtgtgtactc atggcattca ggtaaaggag
    22741 tggatgaagg caatatctgg ggtgactact attacctaga agcccttatc cgtttctaca
    22801 aagactggaa cctatattgg taggaggaga aatatgacaa tgccaaatat tattatgacc
    22861 cgtatcgatg aacggttgat tcatggacaa ggacaacttt gggtaaaata cctaggttgt
    22921 aatacggtca ttgttgccaa tgacgaagta agcacggaca agatgcaaca aactctgatg
    22981 aaaacagttg tgccagactc agttgccatg cgtttcttcc ctttgcaaaa ggtgattgat
    23041 atcattcaca aggctaatcc tgctcaaacg atctttatcg ttgtaaagaa tgtgaaggat
    23101 gctttaacct tggtagaagg tggtgtccct atcaaagaaa tcaatattgg gaacattcac
    23161 aatgctactg gtaaagagca agtgacacgc tccatcttcc tgggtgaaga ggacaaggcg
    23221 gccctcaagg aattgagcca aactcatcaa gtaacattta atacgaaaac aactccaaca
    23281 ggaaatgatg gagctgttca agtcaacatt atggactata tttaaaagag gagatcgtta
    23341 tgtcgattaa tgtatttcaa gcgattttaa ttggattatg gacagctttc tgttttagtg
    23401 gaatgctgtt aggaatttac accaatagat gcattgttct gtcatttggt gtcggaatta
    23461 ttctaggtga tctgcctact gctcttgcaa tgggagctat tggtgaattg gcttatatgg
    23521 gattcggtgt tggtgctgga ggtactgttc caccaaaccc aatcggacct ggtatctttg
    23581 gtaccttgat ggctatcact agtgctggta aagtcagtcc agaagcggct cttgccctct
    23641 ctactccgat tgctgtggcg attcaattct tacaaacttt cgcctacact gtacgtgctg
    23701 gtgcgcctga aacagcgatg aagcacttga aaaaccataa tttgaagaaa tttaagttca
    23761 ctctaaatgc aacaatttgg ttgtttgcct ttattggatt taccttgggt tgcttgggtg
    23821 ccctttcaat ggataccttg ttgaaactcg tagactacat tccaccggta ttgcttacag
    23881 gtttgacagt tgctggtaaa atgctcccag ctatcggttt tgcgatgatc ttgtcagtga
    23941 tggctaagaa agagttgatt ccctttgtct tgttgggata tgtttgtgca gcttatctaa
    24001 acatcccaac aattggtatt gcaattgtag gtactatctt tgctttgatt gaattttata
    24061 acaagccaaa aacagcggat catgtggtag aggaggaagc acacgatgac tggatctaac
    24121 aaattaacaa aacgtgatta tcttaaaacg tctttgcggg cattcttttg tcaaaatgga
    24181 tttaactata gtaactatca agggttggga tatgccaatg tgatgtatcc tgctttgaaa
    24241 aaacactatg gagaggatca ggaaggtttc taccaagcct tggaagaaaa ctgtgaattc
    24301 tataatacca acccacactt cctgcctttt attaccagct tgcatcttgt aatgttggaa
    24361 aatggccgtc cggcaaaaga aacacgtagc atcaagatgg ccttgatggg accattggca
    24421 ggtattgggg attctctttc tcaattctgt ttagctccat tgttctcaac catcgcagct
    24481 tcgtttgctc aagaaggctt ggttgtcggt ccaatcttgt tcttccttgc gatgaatacg
    24541 attttaacag cgattaaatt gtcaactggt ctgtatggat acaaactagg aacaactgtg
    24601 attgataaac taagcgaaca gatggcaacg atttctcgta ttgccaatat tatcggtgta
    24661 accgtaattg ctggtttggc agcgacatct gttaagatta tggtgccgat tacctttgct
    24721 gcaggggaag ttaaagcaga cgctaaacaa agtatcgtaa gtattcaggg aatgcttgat
    24781 aaggttgctc cagctcttct accagcccta tttacacttt tagtttacta cttgatcaaa
    24841 gaaaagaaat ggacaacata taaactcgtt attttaacag ttatcatcgg aattatcgga
    24901 agctggctta agattatagc ttaatggata caacattgtt ttatggaata gtgattgtct
    24961 tggcagtgag tcccctttta ctgtcaagct ttcattctat tcgtcagcaa aagttgcttc
    25021 gcaaacagat ggagcaacga caagagtatt tagcttcttt aacatctggt gatgaagtgt
    25081 tgttattgtc tggaattcat ggaaaaatca tttctatcaa agatgacttg gtctccttgc
    25141 agattgcaaa aggtgtggtc atctatgtag aaaaggaaag tgtaatggga aagacaaaag
    25201 aactgctttt taagtagttc tttttctggt aatagataat gaaagaagaa agaagacaat
    25261 tttttgaaag aatcgatgga aaccaatgtc gtgattatat cttgtcccac tgttcaaaag
    25321 actatgagaa agtcaagagt tcccttgaac gcttgatgga caatcgtttt atgtttgata
    25381 gtccttggga tatggagcct tgttcaaaaa tccatcaaat ccagccgatg gtatgggatc
    25441 aagtatttga agatgatcca gaatgggctt atatgctcaa tcgacaagaa tatctcttgc
    25501 agtttatgat agggtatctg gtagaaggag ataagagcta tattcaaaag tgcaagttct
    25561 ttctatttga ttggattgag caggtgagag aattttctcc tcaatccttg atgactagaa
    25621 ccttggatac gggtattcgt tcctttactt ggttgaaact actcttgctc ctcttgaaat
    25681 ttgacttgct agaggagaaa gaactagaga aaattttggt cagtctagaa aagcagattg
    25741 actttatgaa aagccactat cgcgccaagt acacccttag taactggggg attttacaaa
    25801 caattccgat gcttgctatc tattatttct tttcagataa gatggatcta gaagaagctt
    25861 accattttgc ttcagaggag ttgaaacagc aaattgagac acagatttta ggagatggaa
    25921 gccagtttga acagtcgatt ctctatcatg tagaggttta taaagccttg ctggatttgt
    25981 gtctcttgct tccagacttg caagatagtt accgagagtt gctggaaaag atggcgacct
    26041 atattcaaat gatgacaggc ttagatggac gaactttggc ttttggtgat agcgattcta
    26101 cagaaacgac agaaattttg agcctgtctg ctgtggtttt gaacaaggaa gaccttctta
    26161 acggtctgga tgttaaagtc gatttgctta gcctcttgtt cctggggcga gaaaaggtca
    26221 agcgactgca ggaatttgaa aggagagctt ggcagcctaa gtccatgatc tttgaagact
    26281 ctggacatgt ctgcattaag gatgaacatc gttatctatt tttcaaaaat ggtccgctag
    26341 gaagtgccca tagccatagt gacgagaata gtttttgctt acagtatcaa ggccaaccta
    26401 ttttcataga tgctgggcgt tattcttatc gggagatata tgaacgttat ctcttaaata
    26461 gtgcttggag tcattcgacc tgcattgtag atgggaaagc tccggaaaga atcacgggat
    26521 cctgggaata tgaatactat cctcactccc tgttttgtca ccataaagaa agggagggag
    26581 tgcattatat tgagggggct tattggtcag cagaacctga tttgccttat cttcacaaga
    26641 gaaaaatcct catgttggta gaggatgtct ggctcttggt agatgacatc aggtgtcaag
    26701 gtcagcatga ggcgttgact cagtttatcc ttgacaagga tgtgacctat caagatggga
    26761 aaatcaatca gttgagacta tggagtgaag ttgattttga tttggaagat accatcattt
    26821 ctcctaaata caatgagctt gaaagaagta gcaaactcac caagcgccaa ttctttgaga
    26881 atcagatgct ggattatacc atcattgcgc atgagagttt tgaaatcatc cgtcattctg
    26941 tctaccagac agatgatcgt gaagtggaaa atgctctggc ttttgaagtg aaaaatgacg
    27001 aaacagacaa gctgattctg ttattaagcg aggatattgg tgtaggtgaa aaattgtgcc
    27061 tcgttgacgg aacaaaaatg cgtggaaaat gtctagtata tgataaaata aatgagagaa
    27121 tgattcgctt gcagtgctag aaataggcat tttgaatagt gaatatgtta taataagtat
    27181 tagtaggagg tgttttagat tggagaagaa actgaccata aaagacattg cggaaatggc
    27241 tcagacctcg aaaacaaccg tgtcatttta cctaaacggg aaatatgaaa aaatgtccca
    27301 agagacacgt gaaaagattg aaaaagttat tcatgaaaca aattacaaac cgagcattgt
    27361 tgcgcgtagc ttaaactcca aacgaacaaa attaatcggt gttttgatcg gtgatattac
    27421 caacagtttc tcaaaccaaa ttgttaaggg aattgaggat atcgccagcc agaatggcta
    27481 ccaggtaatg ataggaaata gtaattacag ccaagagagt gaggaccggt atattgaaag
    27541 catgcttctc ttgggagtag acggctttat tattcagccg acctctaatt tccgaaaata
    27601 ttctcgtatc atcgatgaga aaaagaagaa aatggtcttt tttgatagtc agctctatga
    27661 acaccggact agctgggtta aaaccaataa ctatgatgcc gtttatgaca tgacccagtc
    27721 ctgtatcgaa aaaggttatg agcattttct cttgattaca gcggatacga gtcgtttgag
    27781 tactcggatt gagcgggcaa gtggttttgt ggatgcttta acagatgcta atatgcgtca
    27841 cgccagtcta accattgaag ataagcatac gaatttggaa caaattaaag aatttttaca
    27901 aaaagaaatc gatcccgatg aaaaaactct ggtatttatc cctaactgtt gggccctacc
    27961 tctagtcttt accgttatca aagagttgaa ttataacttg ccacaagttg ggttgattgg
    28021 ttttgacaat acggagtgga cttgcttttc ttctccaagt gtttcgacgc tggttcagcc
    28081 ctcctttgag gaaggacaac aggctacaaa gattttgatt gaccagattg aaggccgcaa
    28141 tcaagaagaa aggcaacaag tcttggattg tagtgtgaat tggaaagagt cgactttcta
    28201 aaatgaagga aaatgacttg caatctctgt taagaaataa aataatccca cctagaacaa
    28261 gctaggtggg attatttgcc tatgaaatga gaaattatgg gagcaagctc ctaaatcaac
    28321 tgtttttgat ctacttcttt aactacttga taaaagttat agaagtaggc caaacttgaa
    28381 atgatggtta cgactaggaa tattgaaaat ttccattgga cagggttggt taaaagttgt
    28441 ggaaaggata tgaggagaaa gaagagggct gcgttgagga caggtatccg ttttgattgt
    28501 attttctcaa gtcctttatt gagcgcagga agaaagagga gtaggagtag taaaactgta
    28561 tgagaaacag ctcctgaaat aagggcaaag aaaaggaaaa tactgataaa aacatgaatg
    28621 atcagtagtc tagctagtga tttcataagg tacctcctaa tcctggtctt ttttagctct
    28681 tgcaatacga agtgagtcga caatatgtat catcactccg aaaaagaaag ctcccagtat
    28741 agttttaaaa atatgttttg tatttagaag agaactgata aaatttggat tttcacttgt
    28801 tagggtatca atgagtggaa ttataaaaaa tatcactgtt ccataaatcg aacctgcttt
    28861 cagaccagga taacgtaact gtttcttttc ttttttcatg agtttgctcc ttttttaaaa
    28921 atcttcctcc caaaagagac tgttgaggtc agtttggagg ctgcgggcga gattgagaca
    28981 gagttccaag gttggattgt acttgtcgtt ttcaatcata ttgatagtct gtctcgagac
    29041 accgatattc ttggcgagct cgagctggga aatgcccagt tccttgcgaa attctttcac
    29101 acgattcatc tgttcttctt tctgatttat gtcgtatata tttgactata ttatagtctt
    29161 ttaaacataa agtgtcaagt atttttgaca tattttttga agaaatagta gtctccttgt
    29221 cctatttgtc tgacaagtgc aagctggtcg gatttgtggt aaaatagata agatatgaca
    29281 aaagaatttc atcatgtaac ggtcttactc cacgaaacga ttgatatgct tgacgtaaaa
    29341 cctgacggta tctacgttga tgcgactttg ggtggagcag gccatagcga gtatttatta
    29401 agtaaattaa gtgaaaaagg ccatctctat gcctttgacc aggatcagaa tgccattgac
    29461 aatgcgcaaa aacgcttggc accttacatt gagaagggaa tggtgacctt tatcaaggat
    29521 aacttccgtc atttacaggc acgtttgcgc gaagctggtg ttcaggaaat tgatggaatt
    29581 tgttatgact tgggagtgtc tagtcctcaa ttagaccagc gtgagcgtgg tttttcttat
    29641 aaaaaggatg cgccactgga catgcggatg aatcaggatg ctagtctgac agcgtatgaa
    29701 gtggtgaaca attatgacta tcatgacttg gttcgtattt tcttcaagta tggagaggac
    29761 aaattctcta aacagattgc gcgtaagatt gagcaagcgc gtgaagtgaa gccgattgag
    29821 acaacgactg agttagcaga gattatcaag ttggtcaaac ctgccaagga actcaagaag
    29881 aagggtcatc ctgctaagca gattttccag gctattcgaa ttgaagtcaa tgatgaactg
    29941 ggggcggcag atgagtccat ccagcaggct atggatatgt tggctctgga tggtagaatt
    30001 tcagtgatta cctttcattc cttagaagac cgcttgacta agcaattgtt caaggaagct
    30061 tcaacagttg aagttccaaa aggcttgcct ttcatcccag atgatcgcaa gcccaagatg
    30121 gaattggtgt cccgtaagcc aatcttgcca agtgcggaag agttagaagc caataaccgc
    30181 tcgcactcag ccaagttgcg cgtggtcaga aaaattcaca agtaagaggg aaaaagatgg
    30241 cagaaaaaat ggaaaaaaca ggtcaaatac tacagatgca acttaaacgg ttttcgcgtg
    30301 tggaaaaagc tttttacttt tccattgctg taaccactct tattgtagcc attagtatta
    30361 tttttatgca gaccaagctc ttgcaagtgc agaatgattt gacaaaaatc aatgcgcaga
    30421 tagaggaaaa gaagaccgaa ttggacgatg ccaagcaaga ggtcaatgaa ctattacgtg
    30481 cagaacgttt gaaagaaatt gccaattcac acgatttgca attaaacaat gaaaatatta
    30541 gaatagcgga gtaagatatg aagtggacaa aaagagtaat ccgttatgcg accaaaaatc
    30601 ggaaatcgcc ggctgaaaac agacgcagag ttggaaaaag tctgagttta ttatctgtct
    30661 ttgtttttgc cattttttta gtcaattttg cggtcattat tgggacaggc actcgctttg
    30721 gaacagattt agcgaaggaa gctaagaagg ttcatcaaac cacccgtaca gttcctgcca
    30781 aacgtgggac tatttatgac cgaaatggag tcccgattgc tgaggatgca acctcctata
    30841 atgtctatgc ggtcattgat gagaactata agtcagcaac gggtaagatt ctttacgtag
    30901 aaaaaacaca atttaacaag gttgcagagg tctttcataa gtatctggac atggaagaat
    30961 cctatgtaag agagcaactc tcgcaaccta atctcaagca agtttccttt ggagcaaagg
    31021 gaaatgggat tacctatgcc aatatgatgt ctatcaaaaa agaattggaa gctgcagagg
    31081 tcaaggggat tgattttaca accagtccca atcgtagtta cccaaacgga caatttgctt
    31141 ctagttttat cggcctagct cagctccatg aaaatgaaga tggaagcaag agcttgctgg
    31201 gaacctctgg aatggagagt tccttgaaca gtattcttgc agggacagac ggcattatta
    31261 cctatgaaaa ggatcgtctg ggtaatattg tacccggaac agaacaagtt tcccaacgaa
    31321 cgatggacgg taaggatgtt tatacaacca tttccagccc cctccagtcc tttatggaaa
    31381 cccagatgga tgcttttcaa gagaaggtaa aaggaaagta catgacagcg actttggtca
    31441 gtgctaaaac aggggaaatt ctggcaacaa cgcaacgacc gacctttgat gcagatacaa
    31501 aagaaggcat tacagaggac tttgtttggc gtgatatcct ttaccaaagt aactatgagc
    31561 caggttccac tatgaaagtg atgatgttgg ctgctgctat tgataataat acctttccag
    31621 gaggagaagt ctttaatagt agtgagttaa aaattgcaga tgccacgatt cgagattggg
    31681 acgttaatga aggattgact ggtggcagaa tgatgacttt ttctcaaggt tttgcacact
    31741 caagtaacgt tgggatgacc ctccttgagc aaaagatggg agatgctacc tggcttgatt
    31801 atcttaatcg ttttaaattt ggtgttccga cccgtttcgg tttgacggat gagtatgctg
    31861 gtcagcttcc tgcggataat attgtcaaca ttgcgcaaag ctcatttgga caagggattt
    31921 cagtgaccca gacgcaaatg attcgtgcct ttacagctat tgctaatgac ggtgtcatgc
    31981 tggagcctaa atttattagt gccatttatg atccaaatga tcaaactgct cggaaatctc
    32041 aaaaagaaat tgtgggaaat cctgtttcta aagatgcagc tagtctaact cggactaaca
    32101 tggttttggt agggacggat ccggtttatg gaaccatgta taaccacagc acaggcaagc
    32161 caactgtaac tgttcctggg caaaatgtag ccctcaagtc tggtacggct cagattgctg
    32221 acgagaaaaa tggtggttat ctagtcgggt taaccgacta tattttctcg gctgtatcga
    32281 tgagtccggc tgaaaatcct gattttatct tgtatgtgac ggtccaacaa cctgaacatt
    32341 attcaggtat tcagttggga gaatttgcca atcctatctt ggagcgggct tcagctatga
    32401 aagactctct caatcttcaa acaacagcta aggctttgga gcaagtaagt caacaaagtc
    32461 cttatcctat gcccagtgtc aaggatattt cacctggtga tttagcagaa gaattgcgtc
    32521 gcaatcttgt acaacccatc gttgtgggaa caggaacgaa gattaaaaac agttctgctg
    32581 aagaagggaa gaatcttgcc ccgaaccagc aagtccttat cttatctgat aaagcagagg
    32641 aggttccaga tatgtatggt tggacaaagg agactgctga gacccttgct aagtggctca
    32701 atatagaact tgaatttcaa ggctcgggct ctactgtgca gaagcaagat gttcgtgcta
    32761 acacagctat caaggacatt aaaaaaatta cattaacttt aggagactaa tatgtttatt
    32821 tccatcagtg ctggaattgt gacattttta ctaactttag taggaattcc ggcctttatc
    32881 caattttata gaaaggcgca aattacaggc cagcagatgc atgaggatgt caaacagcat
    32941 caggcaaaag ctgggactcc tacaatggga ggtttggttt tcttgattac ttctgttttg
    33001 gttgctttct ttttcgccct atttagtagc caattcagca ataatgtggg aatgattttg
    33061 ttcatcttgg tcttgtatgg cttggtcgga tttttagatg actttctcaa ggtctttcgt
    33121 aaaatcaatg aggggcttaa tcctaagcaa aaattagctc ttcagcttct aggtggagtt
    33181 atcttctatc ttttctatga gcgcggtggc gatatcctgt ctgtctttgg ttatccagtt
    33241 catttgggat ttttctatat tttcttcgct cttttctggc tagtcggttt ttcaaacgca
    33301 gtaaacttga cagacggtgt tgacggttta gctagtattt ccgttgtgat tagtttgttt
    33361 gcctatggag ttattgccta tgtgcaaggt cagatggata ttcttctagt gattcttgcc
    33421 atgattggtg gtttgctcgg tttcttcatc tttaaccata agcctgccaa ggtctttatg
    33481 ggtgatgtgg gaagtttggc cctaggtggg atgctggcag ctatctctat ggctctccac
    33541 caggaatgga ctctcttgat tatcggaatt gtgtatgttt ttgaaacaac ttctgttatg
    33601 atgcaagtca gttatttcaa actgacaggt ggtaaacgta ttttccgtat gacgcctgta
    33661 catcaccatt ttgagcttgg gggattgtct ggtaaaggaa atccttggag cgagtggaag
    33721 gttgacttct tcttttgggg agttgggctt ctagcaagtc tcctgaccct cgcaattttg
    33781 tatttgatgt aagaatggca ccctgatgtt tcagggtgtt tttgtgttta aatacacaat
    33841 gaaaatcaaa gaacaaacta gaaagctaac tttaggctgc tcaaaatata atatattgaa
    33901 actagaatag tacacctcta cttctaaaac attgttagaa atcgatttga ctgtcctgaa
    33961 cgatttatcc tgttcttatt tcattttact atacagtttc gaggttgtag ataaggcgaa
    34021 gctgatgtgg tttgaagaga ttttcgaaga gataaaaaat attggtcaat taaagtcaaa
    34081 atccttgacc ttttctgact aatgtagtat attatgaacg taaggtaaat gaaagcctta
    34141 ctagaacact tatttaaagt aaaatagaaa gaggtggggt ctatgtttaa tctagaaatc
    34201 ttcagaagta aagatggtct actcctgctt gaaaaagaaa aaccagaaat agtacgtagg
    34261 gtagcggttt agctagtcta aattttttaa aacaaaggtc aaagatagtc aatatcagta
    34321 atcataacta agtaaacaaa aagaggtaaa gaatatgaat aacaacttta ataattttaa
    34381 taacatggat gatttattta accaattgat gggtggtatg cgaggataca gttctgaaaa
    34441 tcgccgttac ttaattaatg ggcgcgaagt cacacctgag gaatttgctc actatcgtac
    34501 gactggtcaa ttaccaggaa atgcagaaac tgatgtgcaa atgtcacaac aggcatcagg
    34561 tatgaaacaa gacggtgtcc ttgcaaaact aggtcgaaac ttgacagcag aagcgcgtga
    34621 gggtaagttg gatcctgtta tcggacgaaa caaggaaatt caagaaacat ctgaaatcct
    34681 ctcacgccgc accaagaaca atcctgtttt ggtcggagat gcaggtgttg gtaagacagc
    34741 agttgtcgaa ggtctagcgc aagccattgt gaacggagat gttcctgctg ctatcaagaa
    34801 caaggaaatt atttctattg atatctcagg tcttgaggct ggtactcaat accgtggtag
    34861 ctttgaagaa aatgtccaaa acttagtcaa tgaagtgaaa gaagcaggga atattatcct
    34921 cttctttgat gaaattcacc aaattcttgg tgctggtagc actggtggag acagtggttc
    34981 taaaggactt gcggatattc tcaagccagc tctctctcgt ggagaattga cagtgattgg
    35041 ggcaacaact caagacgaat accgtaacac catcttgaag aatgctgctc ttgctcgtcg
    35101 tttcaacgaa gtgaaggtca atgctccttc agcagagaat acttttaaca ttcttcaagg
    35161 cattcgtgac ctctatcaac aacatcacaa tgtcatcttg ccagacgaag tcttgaaagc
    35221 agcggtggat tattctgttc aatacattcc tcaacgtagc ttgccagata aggctattga
    35281 ccttgtcgat gtaacagctg ctcacttggc ggctcaacat ccagtaacag atgtgcatgc
    35341 tgttgaacga gaaatcgaaa cggaaaaaga caagcaagaa aaagcagttg aagcagaaga
    35401 ttttgaagca gctctaaact ataaaacacg cattgcagaa ttggaaaaga aaatcgaaaa
    35461 ccacacagaa gatatgaaag tgactgcaag tgtcaacgat gtggctgaat ctgtggaacg
    35521 aatgacaggt atcccagtat cgcaaatggg agcttcagat atcgaacgtt tgaaagatat
    35581 ggctcatcgc ttgcaagaca aggtgattgg tcaagataag gccgtagaag ttgtagctcg
    35641 tgctatccgt cgtaaccgtg ctggttttga tgaaggaaat cgcccaatcg gcaacttcct
    35701 ctttgtaggg tctactgggg ttggtaagac ggagcttgct aagcaattgg cactcgatat
    35761 gtttggaacc caggatgcga ttatccgttt ggatatgtct gaatacagtg accgcacagc
    35821 tgtttctaag ctaattggta caacagcagg ctatgtgggt tatgatgaca atagcaatac
    35881 cttaacagaa cgtgttcgtc gcaatccata ctctatcatt ctcttggatg aaattgaaaa
    35941 ggctgaccct caagttatta cccttctcct ccaagttcta gatgatggtc gtttgacaga
    36001 tggtcaagga aatacagtaa acttcaagaa cactgtcatt attgcgacct caaatgctgg
    36061 atttggctat gaagccaact tgacagaaga tgcggataaa ccagaattga tggaccgttt
    36121 gaaacccttc ttccgtccag aattcctcaa ccgctttaat gcagtcatcg agttctcaca
    36181 cttgactaag gaagaccttt ctaagattgt agatttgatg ttggctgaag ttaaccaaac
    36241 cttggctaag aaagacattg acttggtagt cagtcaagcg gctaaagatt atatcacaga
    36301 agaaggttac gacgaagtca tgggggttcg tcctctccgt cgagtggttg aacaagaaat
    36361 tcgtgataag gtgacagact tccacttaga tcatttagat gctaaacatc tggaagcaga
    36421 tatggaagat ggcgttttgg ttattcgtga gaaagcctaa gatagaattt tgaggataaa
    36481 aaagaaggag ccagctgaaa aaaactggtt ccttttgagg tacgacgggc atgtcgtaca
    36541 gtagaagtgt actattctag tttcaatcca ctatagtagc tcagaagtcg gtacttaaac
    36601 gtgctatatc aaaaccagtc cttgaaaaac gtgga
//
LOCUS       DAVHKZ010000018        36583 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000018 DAVHKZ010000000
VERSION     DAVHKZ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36583
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.018"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(310..2037)
                     /gene="ezrA"
                     /locus_tag="VVO74_001095"
     CDS             complement(310..2037)
                     /gene="ezrA"
                     /locus_tag="VVO74_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU5695123.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAESYNHSF
                     CFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2119..4065)
                     /gene="gyrB"
                     /locus_tag="VVO74_001096"
     CDS             complement(2119..4065)
                     /gene="gyrB"
                     /locus_tag="VVO74_001096"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU5695124.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4080..4643)
                     /locus_tag="VVO74_001097"
     CDS             complement(4080..4643)
                     /locus_tag="VVO74_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU5695125.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTSFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4728..5282)
                     /locus_tag="VVO74_001098"
     CDS             complement(4728..5282)
                     /locus_tag="VVO74_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU5695126.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGNLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5293..6516)
                     /locus_tag="VVO74_001099"
     CDS             complement(5293..6516)
                     /locus_tag="VVO74_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU5695127.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPRLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6553..9003)
                     /locus_tag="VVO74_001100"
     CDS             complement(6553..9003)
                     /locus_tag="VVO74_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU5695128.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSCRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVVSLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9203..10132)
                     /locus_tag="VVO74_001101"
     CDS             complement(9203..10132)
                     /locus_tag="VVO74_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU5695129.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10272..10559
                     /locus_tag="VVO74_001102"
     CDS             10272..10559
                     /locus_tag="VVO74_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU5695130.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10593..11927)
                     /gene="ciaH"
                     /locus_tag="VVO74_001103"
     CDS             complement(10593..11927)
                     /gene="ciaH"
                     /locus_tag="VVO74_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU5695131.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(11917..12591)
                     /gene="ciaR"
                     /locus_tag="VVO74_001104"
     CDS             complement(11917..12591)
                     /gene="ciaR"
                     /locus_tag="VVO74_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU5695132.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12700..15246)
                     /locus_tag="VVO74_001105"
     CDS             complement(12700..15246)
                     /locus_tag="VVO74_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU5695133.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15369..15809)
                     /locus_tag="VVO74_001106"
     CDS             complement(15369..15809)
                     /locus_tag="VVO74_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU5695134.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15784..16653)
                     /locus_tag="VVO74_001107"
     CDS             complement(15784..16653)
                     /locus_tag="VVO74_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEU5695135.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLDRILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16631..17131)
                     /locus_tag="VVO74_001108"
     CDS             complement(16631..17131)
                     /locus_tag="VVO74_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU5695136.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17142..17840)
                     /locus_tag="VVO74_001109"
     CDS             complement(17142..17840)
                     /locus_tag="VVO74_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU5695137.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDAYKPLLEQTAQEIQEIFEINYMTPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(17833..18069)
                     /locus_tag="VVO74_001110"
     CDS             complement(17833..18069)
                     /locus_tag="VVO74_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU5695138.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(18169..19095)
                     /locus_tag="VVO74_001111"
     CDS             complement(18169..19095)
                     /locus_tag="VVO74_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU5695139.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19170..19985)
                     /locus_tag="VVO74_001112"
     CDS             complement(19170..19985)
                     /locus_tag="VVO74_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695140.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(19989..20309)
                     /locus_tag="VVO74_001113"
     CDS             complement(19989..20309)
                     /locus_tag="VVO74_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU5695141.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(20561..20641)
                     /locus_tag="VVO74_001114"
                     /pseudo
     CDS             complement(20561..20641)
                     /locus_tag="VVO74_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(20685..22682)
                     /gene="metG"
                     /locus_tag="VVO74_001115"
     CDS             complement(20685..22682)
                     /gene="metG"
                     /locus_tag="VVO74_001115"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU5695142.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(22806..24065)
                     /locus_tag="VVO74_001116"
     CDS             complement(22806..24065)
                     /locus_tag="VVO74_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5695143.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(24067..24768)
                     /locus_tag="VVO74_001117"
     CDS             complement(24067..24768)
                     /locus_tag="VVO74_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695144.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(24752..25951)
                     /locus_tag="VVO74_001118"
     CDS             complement(24752..25951)
                     /locus_tag="VVO74_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU5695145.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            26237..27583
                     /gene="gor"
                     /locus_tag="VVO74_001119"
     CDS             26237..27583
                     /gene="gor"
                     /locus_tag="VVO74_001119"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU5695146.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            27780..28316
                     /locus_tag="VVO74_001120"
     CDS             27780..28316
                     /locus_tag="VVO74_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU5695147.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(28517..28732)
                     /locus_tag="VVO74_001121"
     CDS             complement(28517..28732)
                     /locus_tag="VVO74_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU5695148.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            28830..29150
                     /locus_tag="VVO74_001122"
     CDS             28830..29150
                     /locus_tag="VVO74_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695149.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(29181..29519)
                     /locus_tag="VVO74_001123"
     CDS             complement(29181..29519)
                     /locus_tag="VVO74_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695150.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(29531..30250)
                     /gene="trmD"
                     /locus_tag="VVO74_001124"
     CDS             complement(29531..30250)
                     /gene="trmD"
                     /locus_tag="VVO74_001124"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU5695151.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(30240..30758)
                     /gene="rimM"
                     /locus_tag="VVO74_001125"
     CDS             complement(30240..30758)
                     /gene="rimM"
                     /locus_tag="VVO74_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU5695152.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELTLFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(30788..31576)
                     /locus_tag="VVO74_001126"
     CDS             complement(30788..31576)
                     /locus_tag="VVO74_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU5695153.1"
                     /translation="MKRFEVSTEIGSLSVTYKKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
     gene            complement(32153..32392)
                     /locus_tag="VVO74_001127"
     CDS             complement(32153..32392)
                     /locus_tag="VVO74_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU5695154.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(32412..32684)
                     /gene="rpsP"
                     /locus_tag="VVO74_001128"
     CDS             complement(32412..32684)
                     /gene="rpsP"
                     /locus_tag="VVO74_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU5695155.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            32854..33063
                     /locus_tag="VVO74_001129"
     CDS             32854..33063
                     /locus_tag="VVO74_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695156.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LADDSLAGDIILLWRIQFGTFTTET"
     gene            33545..33757
                     /locus_tag="VVO74_001130"
     CDS             33545..33757
                     /locus_tag="VVO74_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695157.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            33841..34644
                     /locus_tag="VVO74_001131"
     CDS             33841..34644
                     /locus_tag="VVO74_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU5695158.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGNGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(34700..36241)
                     /locus_tag="VVO74_001132"
     CDS             complement(34700..36241)
                     /locus_tag="VVO74_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU5695159.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(36243..>36583)
                     /locus_tag="VVO74_001133"
     CDS             complement(36243..>36583)
                     /locus_tag="VVO74_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU5695160.1"
                     /translation="FLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLY
                     LFPNLRKTKKVLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLY
                     KRLHKNKIRN"
BASE COUNT        10866 a         8005 c         6588 g        11124 t
ORIGIN      
        1 ttattggacg gttaccaagt tactcaaagt acagatttga agctgcagat aagactgacg
       61 aaatcacttt aatactaaat gaaaatcaaa aagcaaacta agaagctagc ctcaggctgt
      121 acttgagtac ggtaaggcga cgctgacgtg atttgaagag attttcgaag agtataaaac
      181 actgttttga ggtggtggat aaatcggctg ggtaaaaact caatctcagg agaaaatgaa
      241 gtaaatctcc ccgcaactat agaaaaagat ttgattctgc tcctcacaca ataaaatctt
      301 tttcttttat taaaaacgaa tcgtttcacg tgttttctca tatgaggtaa caaagcgatt
      361 agttacacca ggctctgcca cttccaatgc ttgagaaatc ttgtcaaatg aagcgtgata
      421 atcaaattct ttttcaaaaa tatctaaagc ttcgttaaat gcttcttgaa tgcgttcatc
      481 aaatgagcga tagcggttag aatattgcaa gagttgctct gtcaaagttg catattgtac
      541 aatattataa gtttccgttt ctaaagcttc catatcattc gttgcaattt caagaactcg
      601 ggtaacagat tcaatgttaa tcattttttg ttctaactca accattaaat cctcggtatt
      661 attgcttgcc gtaaagaata acttcaagaa agtttgtgga atacctggca gattgcgttt
      721 ttccatgtat cgcttgatag tatggagacg attgacataa acattggcct tttgacgtgc
      781 attaatatca tctttctcaa tttgtgtcag gcgctcacta actgaaattt gctcatcttc
      841 aatatctttt agttgagttt gtaaatcctc aagattttct tcaagaactg aataagcttg
      901 ggttggttct tcttgattcg aagttacctc aacaatagct gcctcaaaac tctctaattc
      961 tgtctgaata cgacgaacat ggcttgcagc tgtctcagga agtaaatagg tcttgttcaa
     1021 acgtgcaata tcttctccca ataaagtatt attctctttc atatgttgaa ggtaagttgg
     1081 aagagttgca agtagatttt ccactacttt ctgagcagca atttctcgag taaaaatatc
     1141 atacaaggca ttgatttcct cttgtgcctg tccattctca tattcggcat tatccaattc
     1201 caactgacga atattctctt ggtttttctt gaatgcttca taaagcaagt ggaaacgcgc
     1261 ttcaatatcc gtttcaacaa aatgataatt agcatcaatt agtttacgat aaccggcttc
     1321 caaatcctgt aattgatctg gcaattctgt agaaagcgtc gtaaccaagg ctggaacacg
     1381 atccacaata tgacttaagg ccaaaatgtg attttctgta ttatccaaaa tcactgcggc
     1441 ttccacaggg tcacccgatg aattcaaggt tacaaattgt gaaaattcag attggatatt
     1501 ttctaattgt ttttcaattt catccaaggc ttgaccatac tgttctgaat tttcagcaac
     1561 tctatgctga agttcctcaa ataaatccaa agcatgaaga acacgaccac tatttttaga
     1621 ttcttgcttc tctaagtctg ccaaagcatt gcgaattgcc gcaatatctt cttcaatcaa
     1681 agtaatttga ctctcaattt ggtcaatttg atgactggcc ttgagaaaac aaaatgaatg
     1741 gttatagctc tctgcttcaa agagattatt ttcaatatcg gcaaaagagt tgagagataa
     1801 atcgacccat ttttgattcc attcacggaa agccacttga ctttgtccaa tcaagtgcat
     1861 attttttaca gcttctactt catcatttac tggaagattg tatagttctt cttttctttc
     1921 ttctagtgcc tctaatctcc cctcgtttcg cttacgtaga aagattgcca ctacataagc
     1981 cagaactaaa atgactgcaa ttgcaaccat taaataaatt agttgtccat tagacatatc
     2041 aaactccttt tttacttgaa acaatcgtaa cgattatatc atatttttta gaccaaggga
     2101 actacttctc cctatttttt agacatcaag tgtactatag acagcatttt cttcgataaa
     2161 ctcacgacga ggctctactc gatcccccat caacatatca aagattttat ctgcttctgc
     2221 agcatcatct acagaaactc tagccatcaa gcgatgttcg ggatccatgg ttgtttccca
     2281 cagctgatga tcgtccattt cacctagccc cttataacgc tgaatagtcg gtttggtacg
     2341 accttcacta taacgggcta aagcttcttg gagtttgatt tcttgatctg cacccggctg
     2401 gatatattct ttaatctcgc ttccaacctt gacaccatag attggtggtt gggcaatata
     2461 aacataacca gcttctagga ttggtttcat ataacgataa atcaaggtta aaagaagggt
     2521 acgaatgtgg gctccatcga catcggcatc ggtcatcaaa acgagttttt ggtaacgggc
     2581 tttcgaaaca tcaaattctg cgccaaatcc tgttcccatg gctgtgaaaa gactacgaat
     2641 ttcttcgtta gctagaatct tatccatact tgctttttca acgttcaaaa tcttaccgcg
     2701 aattggaagg atagcctgaa actcacggtt acgaccagat ttggctgatc caccagctga
     2761 gtctccttcg acgatgaaga gttctgtttc agcagggtta ttagaagaac agtctgctag
     2821 tttccctgga aggttggaaa tttccaaacc agatttttta cgtgtgactt cacgcgcacg
     2881 cttggcagcc acacgagcct tggcagccaa aattcctttt tctacgatac gtttggcaat
     2941 ctgtggattt tccatgagga aatcggagaa ggcttcactg aagaggcgat tggtaatctt
     3001 gaccacttcg ctatttccca atttggtctt ggtttgtcct tcaaactgtg gatttgggtg
     3061 tttaactgag ataactgcag ttaagccttc gcgaacatct tcccctgtta ggttgtcttc
     3121 attgtctttc agtaacttat ttttacgagc ataatcattg ataacacgtg tcaaggctgt
     3181 acggaaacct tgttcatgcg ttccaccttc atgtgtatga atattattgg cgaaactcat
     3241 gacattttca tggtaaccag ttgtgtactg catggctacc tcaactgtga tatcatccat
     3301 ctcaccgtct gtatagattg gtgtatcaaa gattacatcc ttgttctcgt tgatatattc
     3361 aacgtaacta gcaatcccac cttcataatg ataatgcttg gtttgttcca aaccttggcg
     3421 cttatcagtg atagaaattt gaagaccgcg atttagaaag gccaactctt gaatccgttt
     3481 atttaattta tcaaaatcaa agattgttgt ttcagtgaaa atttctgggt ccggtgtgaa
     3541 gtgaaccgtt gttccagttc tatctgtatc cccaaccacc tcaaggtctg caacaacatg
     3601 accacgacgg tattcttggt aatgaatctt accgttttta tggacatgaa cgtctaattg
     3661 agtggaaagg gcattaacta ctgacgaccc caccccgtga agaccacctg aaaccttgta
     3721 tccaccaccg ccgaactttc ctccagcatg aaggactgta aagacggtct caacagcagg
     3781 acggcctgtt ttttcctgaa tatcgactgg gataccacgc ccatcatcca caacagtaat
     3841 cgaatcatct ggctcaataa aaacttgaat atggctggca aatcctgcca aggcctcgtc
     3901 aattgagtta tcaacaattt cccagactag atggtgaaga ccttcttttg aggttgatcc
     3961 aatgtacatc cctggacgca tacgaacagc ctctaagccc tctaaaactt gaatttgact
     4021 ggcatcataa tcctgtgcct gcagattttt gatttcttct gtcatcttat tcctttttct
     4081 tatatgtcta atacttgtct taaattcacg atactggtaa acaagtgggt atcaagtcct
     4141 gcagcttgac ctgcttcgat atcaatcggc cgatcaccaa tgacaagacc agagctaatc
     4201 tgatactttt ctcttaaata aagcatggat tcgggatttg gctttctctt aaagcctgag
     4261 ctagaagtca ccacttctgt aaaataagct gctatagagg ttttttctaa aatttccaaa
     4321 acctgatcat ttcgatgaga gaccaaaaaa tgacggccac cttgatttga aatgacttcc
     4381 aataggtcag aaactccttc aaataaaatc gggtgttcaa gctctctggc ttcattttcc
     4441 ttgtactttt ctaaaaaatt ctctaaattg ggagcgaatg tctcaatcgc aaaagaagta
     4501 gaaaccttta aagcttgata gacactgtca tggtcttgtg tgataccata cagtgccaat
     4561 gtttcaacaa atgcagctgt tgaagtttca taattatcca gtaaagttcc acctaaatcc
     4621 cagatgtaat cgtgatattt catacccttc attatagcat ttttttatga aaaaagcgat
     4681 gatttccctg agttttccac ataaaaaacg agagaataac tcccgtttta ctgattttta
     4741 ccaaagacat ctcgatagag cattcctgtt cgtaaactct ctgcgtcccc tcctagttgc
     4801 tccaccaact cgtaggcaaa ggcaagggct gttgaaggac cccgactggt tgtcaactga
     4861 ccatctacca ctactgtttc cttgacgtag tgaccatcaa ggatttgctc ttgaacgccg
     4921 tcataacaag tgtatcgctt atttttcaat atctctgctt gattgagggc aattggtgcc
     4981 gcacaaatgg ctgctagttt cttcccttct tgctcgaagc tttgcaattc ttgaatcaag
     5041 gtctgattat cacgtaaatg tgcagaacca ggcatacctc caggaagaac aatcatatca
     5101 tagtctgata aatttccatc aaagacatga tctgctctta cttggattgc atgcgaaccc
     5161 gttacttgct cttcaaaacc aaccatatca catgtgatat tggctcgacg caagacatct
     5221 acaactgtca aggcttcaat ttcttcaaag ccctgagcta acataactgc tacttttacc
     5281 atgattttct ccttatttaa tttgttttaa tacaaccttt ttccgtttga atgggacttt
     5341 tccgctcttt tcttcagcta gattagtctg gtaactcatc gataaaagca aaccaacacc
     5401 aatcagatta ctgataatag ctgatccccc ttgcgaaatg aaaggcaagg gaatccccgt
     5461 caaaggaagt agtccagtca cagcaccgat attctcaaag atgtggaaga gcaacatcat
     5521 aatcaaacct gtggaaatat aagtgtagaa ctggttattt gatttaagag taatcttcaa
     5581 catacggtaa atcaacatga gatagagggc aataaccagg acagagccaa taaagccaaa
     5641 atcttctgca ataaccgtaa aaatcatatc tgactctcga actgggataa gcagattcga
     5701 agcattaaat ccctgaccaa ataagccacc actcccaatg gcaatctgcc cttgagcctg
     5761 ctggtaagtc gttgtttggg caaactcaaa gggattgagc caagccaaaa tccgattgat
     5821 ttggtaggtc ggcattccaa tctggtgaag aaaagctcgt ccgtccttgc taataaagat
     5881 agctaagaaa ccagcaactc ctgttacagc agtcacaaat actgggataa taattttcca
     5941 agaaacccct gataataaaa cgattcctga gaaaatggct acaaaaacca aagccgtccc
     6001 caagtcactt tgaagtgcta aaagaactag gactggaatg gtaaagagaa tcatccagaa
     6061 aattaacaaa aagtccagcg gaaccgtgcg tctccattcc ttatgtttct ttgtaaattg
     6121 gacaatgaca cgagccaaca tgaggatata agatatcttc ataaattctg acggttggaa
     6181 tagggtaatt ccatttattg atacccagtt tttggcaccc gttgatgcaa ctaatcttgg
     6241 attataaaat acaatcggca agatcataag tcccaagcct aaaatatata gaaagggggt
     6301 caccttccaa agaaattctg tattaaagag catgaccaca aaaccaatca caagccccaa
     6361 ggcaatccag gcgacctgct gccctaaaat gggcaaaata ttattgggat aatcatgact
     6421 aacggctata tagatagcca ccacaccgat gaccagtaga aaaaatactg gcaagagcaa
     6481 actgtaatcg actcttgagt cgagagaacg tttcatatat actaacctta tactttcata
     6541 caatactatt tatcaaagtt cattaaaaaa tctatcaata gcctcgtcaa cttcggatcg
     6601 agagatggtt ttaacagtcg cttcttctgc tagagatact actatttgtt tgccgtatcg
     6661 ttttccgacg attctcctat ccaaaataag agttaaggaa cgttggtatt cacgtctcat
     6721 acttcttccc aaagcctgtt ttaaacgaat aatggccatt ggcaattgat aatcataaaa
     6781 ggcatttttc ccttcttgat tcagttcttg attaatcttt ttcgtcaagg gttcttgagg
     6841 attttggaaa ggaagcctcg gtacaacttg aatcacaaaa ggatggcttg aaaaatcaac
     6901 tccctcccag aaacttgctg caccaagcaa gatttgttgt tcaccttttt caaagcgttt
     6961 ctttagctga tgaacatccc catttttata ctgggccaag tggctaactg taagtaaatc
     7021 cgatactgct agaagcatgt ctttagcggt aaagagaacc aaaatcggtt gctggaaagc
     7081 ttgaatttcc actagtaaag cagctacctc tctggcatag acttctaagg aggtttctgt
     7141 taccagaggg aaatctttga ccatgaccac ttcttgttcc tgttttcccc gagattcaat
     7201 cttgacaaat ttggcttcag gatagcctaa aaggtctgcc aaagaaaccc tctgactaat
     7261 ctcaagagta gccgatactc ccaagacttg gcaactctca ggaagtaaag aggacagaag
     7321 agtacggcat gattttgtag aagaaatctg aattttcttt tgactcgttt cagttacttc
     7381 aagccagtaa tcaccttcag ctgtaaaata gcgaaccagc tcatcaaagc cttctacttc
     7441 taattctgaa aaatactgat ggagattgtc cagagaatct aagatatttt tcctagattt
     7501 accagactga aattgttcta tcaagtagag acactcaaag cgaatacttt ctagtatccg
     7561 ttgttgaacc ctgttttctt ctcctactaa agccttatca attaaatcga taatagattg
     7621 tatatcgtag gtctcttgaa gcagattttc tagagctaac aaaatctttt ggacttcatc
     7681 aataatcagt aaacggtcac tgacaaattc aggattatct tcaagtctgg tcacgagata
     7741 ggcatgatta gtcactaaaa gcttgcaagt ctctgccctt tcttgactac gtttccaaaa
     7801 atcttccgtc acaaataagc tctgggatga taaattccca tcatgacgaa ggtctgctag
     7861 aaaatgttgg taacggtaga gttgcccgat ttcatccaaa tctcctgtct ctgtctcagt
     7921 aagccagacc aagacttgca ttttaaagcg tctaaataag cgattttcat cattttcctg
     7981 caaggaatga taaaaggcat ccaacttcag ataattttgt ggtcccttta agctatgaat
     8041 atctgtatgg aacacttcct tgaggcgttt accttcttct tccatgattt gattttgaag
     8101 aatctttgtc ggaacactaa gaacaatttg tcgctctttg gattgagata aagcgggtaa
     8161 gagatagcca taggttttcc caatccctgt cggcgcttga atcagagaga caggttcatc
     8221 tttcaatagc aagccaacct ctttagcaaa actttcttgt tcctccctca cttcaaggtt
     8281 caacagagaa atatttttag aaaagtcttg agatagtttt cgtggctcca gagaagctgc
     8341 cgttttctta aaatacagac cttgaacttg gaccaagtct ggagaactca ggatagattg
     8401 gttgcgataa gtttcctcaa taaccaggta ggactcatat aggagagcgt cagccatttc
     8461 cagcaagcgt tccaagagac ctttaggaag ctgggtcatc ttttcccgta aaaaaagaag
     8521 taattctgct gtagcttggg catctgaaag ggctgtgtgt gcgtgtttaa gaggaattcc
     8581 taattctcga cacaaaatcg gcaagctata tttttccagt tcagggaaaa agacctgggc
     8641 caattcgacc gtatcaacac gagggtttct tagctcatag ccttcaaaaa ataaattttc
     8701 cgccaagaga ttagcatcaa actgaacatt atgggctaca aaaatcccat cctccaccaa
     8761 gtcaaatatt tttctggcaa cttgcgaaaa atcaggtgct tgcgccagac gttggtctgt
     8821 caatcctgtc agttctttga tatgagcatc caagggttca tgtggattga catccgtcgt
     8881 atagtgatcg acgatttctc cgtcctcaat cacgacaatt cccacttgga taattttagc
     8941 cttactacct gtgctagttg cctctaaatc caccacaaca tagcgattac caatcgtttt
     9001 cattataaaa aattatacca aaaaaagggc catttggcac ctgcaaacat aggataattt
     9061 tcaaactcaa gaacactact tttcttaaaa atcccatcga atagagcatt ctagcctgct
     9121 gatttttgta aaatagtgaa gaaatacgaa aaattgagag aagaaatgtt tgcatcttcc
     9181 ttctctcaac gaatcatgta ttttatctaa ccatgtcagg atcgtagtca taaaatcctg
     9241 tatcaaggaa acggttttta gggtgaagtt tacgaacttc ttcatccagc aagaaggctt
     9301 gatcatggct aaagttgccc tcttgaatca agttacgcgc ttggataaag agttttgcaa
     9361 tctcaacaaa gttctgacca ggagtgtaga gcccttctag tttccagcga gtaaagccat
     9421 gctccaccaa ttctgttaat ttgatcatca aatcaaggtc attgttggca aagatatggg
     9481 tcccatgatt atcttcaaaa atggaatagt ggctctctgg atcacttggc tcagccaaga
     9541 agaggtcacg tttatgcgtc ttttcatcat cgatatgtgt aaagttatag tagttttgca
     9601 agagtggacg tttagaatga tggatgacgc tagcaccgta aaccaaaact tcagcaggaa
     9661 tttccaaaat ctctggcatt ttgaaaagtt cagctgatgg aatttcacgc gccaaaacag
     9721 cctcagatgc gccagccttt tgtccccaga agttaatctg acgactgcta gttaccatgg
     9781 ttgaagcatc gtagatggtc ttaaatgaat aaccatcgcg gttaactacg taaaagacgc
     9841 ctgcatcccc aatcgtaata tagtctgtct tgatttcttc caagaagtct aagaaaggct
     9901 tgatacggtc catcatatct tggtgcatga gagcattgac cgcaacgatc aattccttac
     9961 cagcatcatg aaccaactta gcgatttcac gtaattggtc ataactaaag gtcgttggca
    10021 gacgaaggcc aaaatctttc tcaccgacat agatacggtc tacgccagct tcgagtagtt
    10081 gttcaacttg ttcaatactt tcagcagttg ctgtaatgac aatcttttcc ataagaaaaa
    10141 ttataccaca tttctccaaa atcatccatg ctttgaaaat gaaaagggac tttattcttt
    10201 ttgtaacctt tctgtaataa ttctctgccg aaaaaatgat aaaataggta tgtactgtta
    10261 aggagagaat tatgcccgta agaaaattac aatcctatga ggtagactat caagaagaat
    10321 taaaccagca gcttcctcat taccaagctt atacacctga agcgcaatct gatgccaatc
    10381 tcaaggaaat cctatttttt attaatatcg ctgttttttg tatctgtatt gctatcttta
    10441 gttttatctt tttagcatta aaattatcaa ctgctcttgc ctttgccgca gcaatcggat
    10501 tcagcttact tgttttaaaa gttcaacggt ctattatcaa acgaaaacgt agaagataaa
    10561 tccaaaatat cgccccagtt ggagcgatat ttttattttt tctttttaga tggtgtctga
    10621 atggcaatct tcacttcaaa gattgttccc ttgggtttat tatctttgac agtaacagtt
    10681 ccttttagag catctacaat ttgcttggct agggataatc ctaaaccaaa accacctttt
    10741 tgccgggttc tagccttgtc tactcgataa aaacggtcaa aaattttctt tttatcttct
    10801 gtcgaaatac cgattccatt atcagaaaca agtaaataaa gattgcgatc ggtcgccgag
    10861 ataagaaaat caatttcacc atcctcctca gtatacttga cggcattatc gaaaagaatg
    10921 gtcatcagtt gtttcagaag aagctgatct gtgacaattg ttcgatggat acgattttca
    10981 aaacggaaga cacgattatt ttccgaagca atcatctcgt agtttgtgaa agttgtatta
    11041 aaaaagctag ttggaacttc tgcaagctcc ggcttaatcc catcatctct ccgagctaag
    11101 ttcagcaagc ttgtcgttaa aaaacgcata tttcggactt cttccaaact cgatgcaatg
    11161 ctttcgctca catccataat ggtagcttct ggcttacgaa aaagggtctc taagcgattt
    11221 tgcaaaactg cgagtggagt tcgtaactca tgactggcat tttccacaaa agactgttgc
    11281 ttctgcatac tctcaagcag gggcctaaca ctgaccctag ctagatagag actggcaagt
    11341 aaagacaaaa tccagaaact agccatcacg accacaatca attgctcatg cttttgacta
    11401 gcctgttcca actgactggt attaatcaag acagcagcat acttgatatt ggttgaaacc
    11461 gaactaatat tggtctccat caaaatcaca cgatagattt cttcctgccc atagctatta
    11521 aaaacctgaa tctggtagat atgtcctagt tctttctttt ctaacttaat cttatccaag
    11581 cccaaaaatc gatttccaga aagaagttga gtaaagtctt tatcaaagag aatgacttcc
    11641 gtattggaac tgacattagg ttttatttct actttactag cgtccgccct agcattttct
    11701 aaatctttaa tctcttctgt tgccctattt atagccagct gaataactgc ttgaggattt
    11761 tcactcagtc catgaagctt atcgtccacc gaagtataaa gactcgaatg catgacttgt
    11821 aaaataatca gagtcattgt agaaaaaatc agggtgaaga caccgaagtt gcggataaaa
    11881 taactaaagt catccgcata ccatgttttt ttaagtttac tgaacatctt ttaaaagata
    11941 cccaacacta cgcaaagttt gcaaattctc tgcaaaagtg gttcccttta atttcttacg
    12001 gacttttgaa atatagactt cgacaaccga aatcgttgta tcactatcaa atccccatag
    12061 acggtcaaaa atctgcgtct taggtaaaat cacattttga ttttgaagga aataaactag
    12121 taaatcgaac tctttcccca gcaattcgac aggagtatct tcaactttaa cggtattggt
    12181 tgataaatta accacgatat tcccataagt caaggtgttt tcattaaact tccctgaacg
    12241 tttgagaaga gcctgaatcc gcattttaag ttcttctagg tagaaaggtt tggtcagata
    12301 atcatccgct cccagttcaa atccatgtcc cttgtcatcc aaactttcct tggcagtcat
    12361 aatcagaact ggtgtcgtaa ttcccttttc acgcaattct tttaagactt ggaaaccatt
    12421 tttttctggc aacatcaaat ccagcaaaat caagtcatag acaccactct cagcttcgta
    12481 gagaccttct tctccatcaa atacctgcat aacatccgca aaatcgtcta aaaagtcaaa
    12541 tactgaattt gacagaccta ggtcatcctc aaccaataag atttttatca tgagaaactc
    12601 ctccttatta aaactattat accaaatttg ccttaaaaaa aactcaactc tctgcatttt
    12661 acatgagata gctgagtttt ctttttattt taggcttatt tatgcatttc cgtattgaag
    12721 aacaactgct tcgactgcag ctttttcacg gctaatcaag tcaacacgcg ctgcaatttc
    12781 cttgattccc ataccgatgt tacggctaag agcaaggtca gaaagttgcg gctcaaagaa
    12841 ctccttgtat tccgccaagc gttgctgagt cttaaataca tgagcaggaa ggataacaaa
    12901 gctatcaaag ctcatatctc ctccaagggc tgccttaatc caagcccagt tttcacgcgc
    12961 ccaagaccaa gctgttttct gagttgcttg atgagctagg aattggtaat accaagcaga
    13021 caagtcctgt ggtttgacca caaatttgtc cttccaagaa gtaatcaggt tttggatatt
    13081 atccgcatct gtactgtatg caagagctgc tgccaactgg cgtttaaaga cagcatctgt
    13141 tgcgtgagta taagtatcaa gataaagtgc taacaagtct ttagtctcat gatgtttcat
    13201 ctcattaatc agaacttgtg agcgaatagc tgctgggagt cctgcaagat tctccttgtg
    13261 tgttgcgaag atttggctag cgacttgact agcttctgca tcatttgagc gaatcatcat
    13321 cgaaacagcc agctgacgaa ccaattcatc ctcatctgat tctccgtctt tagcttcaaa
    13381 accaagacgg tcatagttat gacgagccaa tttagcaacc agtcctttga aggctgtttc
    13441 agcatccgtt ccttcatcaa taaagcgctc aagggctgaa atcacttgag aaacagctga
    13501 aaccaccaga taagactctt ccttagcaag tttatcaaga actggaagca agtctgcata
    13561 agaaatgtgc cctgcctcag ccaacaaacg acgttcttga acaatttgca gtttgcttgt
    13621 gttatcaagt gtctctagct cagcaagaac agcttctaac aagtctcctt gatagtcggt
    13681 aatatagtgg gcagtatttt cagtgttgag acgaagagct ccttcatttt cagcaagaag
    13741 agctgcgtag ccagggattt cgatactttc agtttcgagt gtatcaggca agcctttcca
    13801 gttgctattg aggggcacca cccagagacg gttcttgtct tcgttctcac cgatgaagaa
    13861 ttgtttttgt gaaatcttca agacatcatt ttcaacttta acagtaagaa ctgggtaacc
    13921 aggctgttcc aaccaagaat ccatgaaggc tgcgacatca cgtcctgacg cttgaccaag
    13981 ggcatcccaa aggtcactac caatggtgtt gctgtattgg tgtttttcaa agtaggcgtg
    14041 caaaccttta gcaaaatcag catctcctag ccaacggcga agcatgtgca tgagacggct
    14101 tcctttggca tagacgatag cgccgtcaaa gagtgtattg atttcatctg gatgtttaac
    14161 ttcgacgtgg acagactgaa cgccatcagt agcgtcacgt tcaagagcaa gaggtactcc
    14221 acctgtttgg aaatcttcaa agatattcca gcttggttcg atggtatcca cacagacgta
    14281 ttccatcata ttagcgaaac tttcattgag ccaaaggtca tcccaccatt tcatagtcac
    14341 gaggttccca aaccattggt gagccaattc atgggccaca acaagggcaa cttgttgacg
    14401 gctagcaaat gtagagttct catcgacaac caagtaaact tcacggtagg tcacaagacc
    14461 ccagttttcc atagcaccag ctgagaagtc aggaagggcg atgtggagag attgaggaat
    14521 tgggtactta actccatagt aatcttcgta aaactcgata gagcgaacag cgatatccag
    14581 tgagaaatca agatttgaaa gtggatgtgc tttggttgag tagacaccta ccagggtacc
    14641 atttttagtt ttagcggtca ccccttgcaa atcaccagca acaaaggcca acaagtaaga
    14701 agacatgcga ggtgttgtct caaacttcca gatacctgtt tccttacggt tttcaacatc
    14761 gatttctggc atgtttgaca aggccaattc accttctgct tggtcaaagc gaagagagag
    14821 gtcaaaagtt gctttggctt caggctcatc cacacatggg aaagcttcgc gcgcaaaatg
    14881 gctctcgaac tgagtagaca agacctcctt cttgactcca tcaactgtat aataagaagg
    14941 gtaaatccct gtcatgttgt ctgtaatttt accagaaaag gcaagaacca attcaacttg
    15001 accagcctca gccaattcga tatgaagggc ttcattgtca tggtcaactg taaatggacg
    15061 agcttgacct gcaacttcta cagaggtgat ttccaagtct ttttggtgga gggagatgcg
    15121 gtcactctgt gcttgaccag tgatggtcac tttcccagaa aaagtcttgg tctcacgact
    15181 caaatctaaa aataaatcat aatgttcagg aacaaattgc ttaataaaat gttcaactgc
    15241 ttgcatagtt ttctcctatt ctaagtttaa gagctgctgc tcttcttcaa acaaacttat
    15301 tatatcatat tttgcttgag aaaaaaggat tggacagcga tttccaaaac tttcttcctt
    15361 ctaatagtct acagtgggta gaccttgcga aattcttcta aaacaacctt gctttcaggt
    15421 gtaaaagtca gccctacttc acccaaacag tctgtgaaaa agtcctcatg aacctggcgc
    15481 caataggcaa gtgatttgtc tccctcacct tccttaaagg catgttgcgc agaaacttga
    15541 ttgaagagtt caacagaaac ctttgtaatt tcgacaatgc agacagactg attttgacta
    15601 tctaaaatga catcgaaggt ccctacttgg ggaagtggtt cgtcttctag tacatagagg
    15661 tcataggctg atgctgttgc tgtcttttct cctttaaaca ccaaatccgc taaaaggtct
    15721 ggttcaactc caaaagccca agcatcgatt tcatctccga tcaaaggatt gatttgcttg
    15781 tatttattcc acatttcttg cggtatcatg ggtactcctt tgtaattttt tactttcttc
    15841 ttttatgtgt ttaagatgat ctggatggtc aatctctaaa tcaaaaatct ctggaataga
    15901 actgtagtgg ataatgcact tgatacccaa ctgattcatt ttttgtatga aagaagtatt
    15961 cagatagcct gctacagcaa aatcaatctt gttctttctt gctttatcct gcatatctct
    16021 tagcatatct aacattattg gactttccat atcatgccat tgactgtttc tcatagtcgc
    16081 aaaaacaaag gaagtcaaat cattcattcc aactacaatc tttgaaatgc ccgtttccag
    16141 tatcctatcc aagtcaaaat acgctgacgg taattcaatc atcgttccga ctttcccagt
    16201 aaagccatac tgacgcaata ctgtaatagc ttgttttaat tggtcggcat cattgacaaa
    16261 aggaaagata agagatagat tgggattggt ttgataaact tctgtaacga catgtgcttc
    16321 agcctgaaat tcatccaaac acgccagtaa acgcctggtt cctctatagc caaacaaggg
    16381 atgcccttcg tcaaaaaact ctctagtccc cactaaacaa ttggcttctg tattcgttaa
    16441 ttcagaaaaa cgataccaaa cttcttcatc tgagtacagg gagcagatag tctctagata
    16501 atcttttaca aattgctgac aacttgctaa tatgatgttt tgattaagct ctctcaacaa
    16561 atattcccca cgaatcatgc cgacgtggtg aaatagttga ggataaattt tttcaagaat
    16621 tttttcgcca ctaagggcaa gttgatttct catcattcac cttccaattc atgtaagaag
    16681 tcttgtccag ttctggaaat cctaataatt cagacttaac cttcaagact aatggcgatg
    16741 cattttcttc tgtaatctct tgaatatcca tccaaatata tccaagtgaa tcattcgcac
    16801 catcagacac agcttccgaa gtcgtaactt gaggtgcact ctcattcatt tcaacatcat
    16861 acaaggccat gacatggtga accataaaat ttgttaactc ttctctgacg aaaacatcgt
    16921 agattcgagg attagagtag cttctaacag taaatcccgt ctcttccata acttctctag
    16981 tcagcgtttc cgtcagtcct tcaccaagtt gctgactgcc tccaggtaga tcataccgat
    17041 gttgataagg gcctctcgtt ttttcaatgc agagtaactt cccattttct aagcaaacag
    17101 cgtagactcc aaagtgtttt ttgatttcca tccaactcct cctacttcaa agaccagcca
    17161 ccatctattg tcaagatttg tccttgcatg gcgctcgctt ttccacttgc taaaaaaaga
    17221 ctaagctctg ctatttcctc tggctcaatc cagcgcttga ttggggtttc actagccacc
    17281 cagtcagcca aaccacctgg ttcaaaatcc gcagcggtca tagctgtctt gactgctcct
    17341 ggagcgatac caaagacctg aatcccagct tcagcatagt ctagagccaa ctgcttggtg
    17401 aagccagcca aggcatgctt ggatgaagta taggcgtgac cacctccacc tgctaggcta
    17461 gaagcaatgg aacacatatt gatgatgatt ccctttttat tttccagcat ttgtgtcaaa
    17521 taataccgag tcaactcaac aggagtcatg tagttaattt caaaaatctc ttgaatttcc
    17581 tgcgcagtct gttccaacag tggtttgtaa gcatccaaaa ctccggcagt attacacaaa
    17641 acatccacct gagggcacca gtcaaaaata ggttccaagt ccaaggtcaa atctctctgt
    17701 aaaaagtgaa aatcaccctc taagagtggc ttttcacctt ggtcaactcc ataaacttga
    17761 tagcccttct ctaaaaagag gcgagcttga gccaatccga tccctgaact cactcctgta
    17821 atgagtacac gtttagtcat gcacttctac ccaatccgtt gccaaaacat cacaagctgt
    17881 cgggctccac atggaaaaac cttctccttc tccagacacg ttgattaaga aataaggtgt
    17941 cacttcaagt gcaagcccat tttgctcgat ggtatcaaag agttggacat agttttcagc
    18001 acctccccaa ccagttcgta catatttttt cttagccttt aagccaggta gaatttcttc
    18061 aaatgtcatg tttttctcct ttaatgtcaa taattctccc cttcattata acaaaaaaac
    18121 cgctttaaaa cggctttttg actgtgattt atttacatct tcttctactt acggcaaatt
    18181 attccctgca gcaagataaa tttcatacca ttcttttctt gttaagctaa agtttgccgc
    18241 ttggctaact tctctcaagt gcttaggatt tgtggtacct acaactgcct gcatttttgc
    18301 tggataacgc aatatccaag aaatggcaat agttgaagag gttactccat atttaatagc
    18361 taaacgatca agtacttgat ttaaagcttg aaatttctca tttccaacaa agttcccttt
    18421 aaaatacccg aattgcaaga cagaccatgc ttgaatgacc acatcgtgta atttgcaata
    18481 ttcaaaaatg ctgccatctc gcatagctgc ttgactatct tccatattaa catgaaaagc
    18541 tgattcaaat cctggagtaa aagccgcact caattgtagc tgattaacag ctaacggctg
    18601 cttgacatct tttttaagca actccatcat cataggattt tgattagaaa ctccaaaatc
    18661 tcgaacttta ccttgtttat aaaggagatc aaaggcttct gctacttggt cagattccat
    18721 caaagcatct ggtcgatgaa ggagcaagct atctagatga tcaatcttca atctttgcaa
    18781 aataccgtct actgatttta taatatagtc cttagaaaaa tcaaaatagg taaattcttc
    18841 aatgcgaatg ccacatttgg actgaatcca catcttttct cttaaatctg gacgattttt
    18901 taggacaaga cctaacagtt cttcacaacg accacgacca taaatatcag ccaagtcgaa
    18961 ggcattgatt ccaacagaaa gtgctgtttc tacaagctct tcaacttctt ttacagactt
    19021 atcttttatt ctcatcattc cgagaacaat ttctgataat tctttgtcat cttgaccaag
    19081 agttatgtat ctcatcaaat ttttctcctt taatttctaa cattcttccc ttcattataa
    19141 caaaaaaccg ctttgcaacg gctttttgac tatacttcac tccattttat cttcttaaac
    19201 ccacggaaca agacaaagat tccaataaag aggacagcta aaggaataac ttttgtaagg
    19261 aaaacatttg aaattcccat ccactcataa taacggagca gagaacccac cacaagatgg
    19321 gcaataatca tactgacaaa tggacgaaag accgcttctt tccaattcca aataccgata
    19381 actagcgaaa tcgtaaagac agacaaacta tcccagggag ccggaatata aaaggctcct
    19441 tcttgtatga agcttgccat tcctacatat cctaaaacaa ctagaagaac tatagtccca
    19501 acaacaatgt aagtgccaat tttcatttta ggagaatctt ggactaaact tcttcgtaaa
    19561 attgtggcca caagtccaaa tccaatcaga aaaataagaa gttgccctaa aaatgtgagc
    19621 aaattgactg ttaagagagg acctttagaa aaatcactta gtagttgata ataacgtaat
    19681 accgccagga caagaattgg cgtcaaaagg gactctttga tagaactgcg aggtgctccc
    19741 ttgagaatct ctttcattat ttttttagga ttcttaccta gataatcctc tgcactcatg
    19801 ccatctcgtt ctgcttctga gaaatctagc atcatcaaat agatctgctc tctgagatag
    19861 tcttcatcat agagaaatcc agcaagatta aaactttccc acaactcctc aaaatacttt
    19921 tgattctcct cagaaaactc atgtagcaaa gcgcttgttt cttcgtaata cttcattttc
    19981 ttcatggttt aacccccatt cttaatccct tctacttttt gactcaaatc gtcccattgt
    20041 tgccaaaaga ctgagacacg ctcttctcct tctttcatta atgaaaaata cttccgatct
    20101 ggaccatctg gcgacgggcg catgtcgcct cttatccatt gatttttttc taacttttgc
    20161 aacaaaggat aaatagttcc tggaacgata gtatcaaatc cagcctctcg caaagtctga
    20221 accaactcat aaccataccg ctctttttga ccaatcatat ccaagacaca accttcaaga
    20281 acacctttta atagctgagt ttctttcatc acttctccct tctaatctat tttgtaatac
    20341 ctactagtaa cttcacctat agtatatcac ttctacacta gtttgtaaag cataatagtt
    20401 aatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cctaccgtat gtatggttac
    20461 tgacttcgtc agtttcatct acaacctcaa aacagtgttt tgagctgact tcgtcagttt
    20521 catctacaac ctcaaaacag tgttttgagc tgacttcgtc agtttcatct acaacctcaa
    20581 aacagtgttt tgagcaacct gcggctagct tcctagtttg ctctttgatt ttcattgagt
    20641 ataaataaaa aaacagaact agtctgaact agtcctgtct acttttaccc aatcacactt
    20701 ccatttggta cagctggatc aactgtgaga agggttaatt tgccatcatg ttcagctgat
    20761 agaatcatac cctggctgac atattttttc atcattttac gtggtttgag gttagcaacg
    20821 atttgaactt tcttgccgac caattcttgt tcatttggat agtattttgc aattcctgaa
    20881 agaatctgac gatcttctcc atcaccagca tccaagcgga attgaagcaa cttatctgaa
    20941 ccttctactt tagacacttc tttgacttct gcgacacgga tttcaacctt gtcaaagtct
    21001 tcaaacttga tttcatcctt gtttagtttg agctcaactt cgtccggatt ccattctttt
    21061 tcgactgctg gtttattgcc ttccatttgt tccttgatat aggcgatttc ttcttccata
    21121 tttagacgtg gaaagatagg tgttcctttg gcaactacag tcacatctgc tgggaagtca
    21181 gccaaactca agttttcaag actagaaact tcttccaaac caagttgagt caaaactgca
    21241 cgactagttt ccatcataaa tggttcaatc aagtgagcaa ctacacgaat gctggctgcc
    21301 aagtggctca tgacacttgc caattggtca cgaagagctt catccttggc caagacccat
    21361 ggtgcggtct catcgatgta tttattggta cgagagatca gagtccagac tgcttcaagc
    21421 gcacgtggat agtcaactgc ttccatgtgt gtatggaagt ctgcgattga ttgttctgca
    21481 acctcagcaa gaacatgatc aaattcagtc acaccttcta cataggcagg gatttgtcca
    21541 tcaaagtact tattaatcat ggaaaccgta cggttaagga ggttcccaag gtcattagcc
    21601 aattcatagt tgatacggcc gacatagtct tcaggagtaa aggttccgtc tgaaccaact
    21661 ggaaggttac gcatgaggta gtaacgaagt ggatctagtc cataacgctc taccaacatt
    21721 tcagggtaaa cgacattccc ttttgactta gacatttttc cgtctttcat gacaaaccaa
    21781 ccatgggcaa tcaaacgatc aggtaattta acatccaaca tcataagaag gattggccag
    21841 tagatagagt ggaagcgaag gatatctttt cctaccatat ggaagactgt tccattccag
    21901 aacttgtcaa agttaccatg ttcgtcttga gcgtagccaa gagctgtcgc atagttaaga
    21961 agggcatcaa tccaaacgta gacaacgtgt tttggatttg atgggacagg cactccccat
    22021 gtaaaggttg tacgagatac cgccaaatct tccaagcctg gctcgatgaa gttgcgtagc
    22081 atttcattaa ggcgaccatc tggcgtgata aattcaggat gagctttgaa aaattcgacc
    22141 aaacggtctt ggtatttgct aaggcgaagg aagtatgatt cttcagaaac ccattcaacc
    22201 tcatgacctg atggagcaat accaccagtc acatttccag cttcatcacg gaaaacttct
    22261 gccagctggc tttctgtaaa gaattcttcg tctgatactg aataccaacc agagtattca
    22321 cccaagtaga tatcatcttg agcaagtaag cgttcaaaga cctgtgcgac aactttttca
    22381 tggtagtcat cggttgtacg gataaattta tcgtatgaga tatctagtaa ttgccagagt
    22441 tctttaactc caaccgccat tccatcaaca taggcttgag gtgtaatacc agcttcttcc
    22501 gctttctgct ggattttctg accatgttca tcaagacctg tcagataaaa tacatcgtag
    22561 cccatcaggc gtttgtaacg tgctaggaca tcacatgcga tagttgtgta ggcagaaccg
    22621 atatgaagtt tcccagatgg atagtaaatc ggcgttgtaa tataaaaatt tttttcagac
    22681 ataatttttc ctttccaggc aaatgaaacc tgtttttcta acacttcatt atatcacatt
    22741 tttaatgaat ttcgataggg aaatccatac aaaaacaaga tagacgagtg tccatcttgt
    22801 tgatctcatt cataacgaag ggcttcaatt ggatcaagtt tcgatgcctt gttggctggc
    22861 aagactccaa aaatcatacc aacactagcc gaaactgcaa gactaaatag ggcaactggg
    22921 attgatactc caacttctat accttctatt aaaccttgca gtaacaaacc tgctaaggca
    22981 gttaaaccac ttgcaattgt caagccaatt aagccaccta acaaggtcaa aatcatggat
    23041 tcaatcaaaa actgaattaa aatattggca cgtgttgcac ccaaagcctt acgaagacca
    23101 atctcacgag tgcgctctgt caccgaaacc agcatgatgt tcatgacacc agttcctcca
    23161 acaaagagag aaatccctgc gatggaacta ataatcgtcg tcataaaact aaacgattgt
    23221 tgaatttctg caaatacaac ggactcatct gccacctggt attctccctg ttgtaagcct
    23281 gcaagctctg tcatttttcg tgccagttct ggacccagag ttggggttaa actggtatca
    23341 ttcactcgaa agacaatatt agctatttca tctacattaa aattcgcagc aagggagata
    23401 ttggtagtaa taggcaagcc accaaaccca tatatttttg atcttttagc ctccggacta
    23461 gtataaaccc caatgacccg gtaactaaat ccattgactt ctacaacctt gttaatagcc
    23521 tcttgaggag attcaaataa actaatggac aattcctcat ctagcaaaat gacacttgca
    23581 aactctttga aatcttgctc tctcagacta cgacctgcaa taatttcatt cttaacagcg
    23641 tccatgtaag ttctgtttcc acctgtcaaa ttagcattct caaccttttt atcttgatag
    23701 gtcaagatgg cattcgttga attggttaca tagtaactat ccactccctt cagtttagct
    23761 gcctcttgaa cccaggattc ttgcggtttt ggcggttcaa caggaacttc ctcttccttt
    23821 ccagaaaccg taaaagctga ttgtttctga gtaaaagacc catctttact ttttttagga
    23881 gagaaaaaga cgctaatatt tttctgagat ttagtcatat ctttattgac ttgacgagat
    23941 agggaatcac ccaaagccat aatcacaaca actgatgaaa caccgataat aatcccaatc
    24001 atagtaagca aagaacgcat cttgtgagcc atgatagatg aaaaggcaaa tttcagattc
    24061 tgcatcttag ttttcctcct ttcctaactg agcactgtca gacgaaatga ccccatcccg
    24121 aatgacaatc tgacgtttgg cataggcagc aatctcaggc tcatgcgtta ccatgataat
    24181 ggtttttcct tctttattca aatcaaccaa taattgcata atttggttac ctgttttggt
    24241 atccaaggct cctgtcggtt catccgctag gataatagaa ggattgttta ccaaggcacg
    24301 cgcaatggct acacgttgct tttgaccacc agataattct gaaggtaaat ggtgactacg
    24361 ttctgtcaat tcaaccttgt ctaaatattc ctcagccaac ttgcgacgtt ttgaagacga
    24421 aactcctgcg taaatcaagg gcaattctac attttgcaga gcattgagct tcgatagaag
    24481 aaagaactgc tgaaagacaa aaccgatttg ttggttacgg accttagcca gttgtttttc
    24541 accaagccca gccacttctt gaccttcaag ataatattct ccactggttg gtgtatccaa
    24601 catgccaatc gtattcatca gagtggactt accagaccca gatggtccca tgatggctac
    24661 aaattcaccc tcattcactt ctagattgat atttttgaga acctgcaatt cttggtcacc
    24721 attacggtag cttctgaaga tattttttag actaattagt tgcttcatca gccttcacct
    24781 cttttccttc ttccaaggaa gatgttggat tactgatgac cttagcaccg ttcgttaaac
    24841 cagaagtgat ttcttgattt tctgcgtcag catttcccaa tgaaacctca acttttttag
    24901 ccttttgttg ttcatccaca atccagacat aatttttact atcatccatt actagactgc
    24961 taacaggaac aagaatagcc ttagttttgc ttttaacctc aatgttgaca gaaaaacctt
    25021 gtttcaaatc accaacctcg cctgtcacat caatagtata agggtattta gaacctgtat
    25081 tattcccggc tgctggacta gctgcttcac cattgttttt aggatagtca gaaatatagc
    25141 ttaatttccc agtccatttt ttatcaggat acactttaga agtaaagctt acttcttgac
    25201 ctacagaaag gttggctaga ttgtactcag acaattctcc cttgacttgt aaattttcat
    25261 tgctgacaat atgaaccata acttggctcg cccctgttgg agatttagaa acattgctat
    25321 tgacttcgac tacagttccc tctagggtac tgagaacagt tgttgcatcc aattgacttt
    25381 gagccttact taattgcgcc gcagcatctg cacgcgcatc acgggcatca cccaattgag
    25441 cgtcaataga agcaacagaa tttccagcca ctggagttgg gctttgcacc gttgcatctt
    25501 ctcctcctac tggcgctggt aactgtggag ccggagctga agcggcttca tttcgtgctt
    25561 gattgagttc attgatatga cgatctgcct tagctactgc tcgactagct gaatcatagg
    25621 ccgcctgcgc ttctgaacta ctgtacttga ctaaagcctg cccttcgctg accttatcgc
    25681 ccacagaaac aaggatttca tctaaatcac ccttactagc atcaaaataa acatattgtt
    25741 cattttttgc tgttactgtc cctgacaata aaacagagga tgccacgctt ccttccttgg
    25801 caacaacaag atgagtaggc tcatctttta gagcagtctg agaaggttgt ctaaagagta
    25861 aaatcccccc ggcacccaat acaactacac tcgcagcacc gattgctgca tacagttgcc
    25921 actttttagc tttaccattc tttttcttca taatgaaact ccttttcttt tttacaatac
    25981 tttgctatta taccaaattt ccctccagca aacaatgcag ttcagatgga aataatggca
    26041 gttcaggatt aaacaatcgt tcggaatttt gcttttctat tgtactagat atataataca
    26101 ctatcttgac ttatttggca agcttttttg caattttttg tgcgtagcag atttttgcaa
    26161 tcaaatcaaa aaaagaataa aatataacta tcaaaaaaga cactctacta tttaaaagat
    26221 tacaaaggag ttttcaatga gagaatatga tatcattgct atcggtggag gtagcggagg
    26281 aatcgctacc atgaaccgtg ctggtgaaca tggagccaaa gcagccgtta ttgaggaaaa
    26341 gaaattaggt ggaacctgtg tcaacgtcgg ttgtgttcct aaaaaaatca tgtggtacgg
    26401 ggcgcaaatc gctgagactt tccatcaatt tggagaagac tacggcttta agactactga
    26461 tcttaacttt aactttgcaa ccctacgtcg caatcgtgaa gcctacattg atcgcgctcg
    26521 ttcttcttat gatggtagtt ttaaacgcaa cggtgtagac ttgattgaag gtcatgctga
    26581 atttgtagat tctcatactg taagcgtaaa tggtgaactg attcgtgcta aacatatcgt
    26641 gattgctaca ggtgcccatc caagtattcc taatattcct ggtgctgagc taggtggctc
    26701 ttctgatgat gtatttgcct gggaagaact tccagagtca attgccattc taggcgctgg
    26761 ttatatcgcc gttgaattag ctggcgtact ccacactttt ggtgtcaaga cagatctctt
    26821 tgttcgccgc gatcgtcctt tacgtggttt tgattcctac atcgttgaag gtttggtcaa
    26881 ggaaatggaa agaacaaact taccacttca cactcacaaa gtccctgtca agttagaaaa
    26941 aactactgac ggcattacca ttcatttcga agatggtact agtcacacag ctagccaagt
    27001 tatctgggct acaggtcgcc gtccaaacgt taagggcttg caacttgaaa aagctggagt
    27061 gactctgaac gaacgtggct ttatccaagt ggatgaatac caaaatactg ttgttgaggg
    27121 aatctatgct ctaggtgatg taacgggcga gaaagaactg actccagttg caatcaaggc
    27181 cggacgtacc ctatctgaac gtctctttaa cggaaaaact actgcaaaaa tggattactc
    27241 aactattcca actgttgtct tttcacaccc tgctatcgga actgttggtt tgacagaaga
    27301 gcaagctatt aaagaatacg gtcaagacca aatcaaggtt tataaatcaa gctttgcatc
    27361 tatgtactct gcttgcactc gcaaccgtca agaatcccgt ttcaaactca taacagctgg
    27421 ttcagaagaa aaagttgtcg gacttcatgg aattggctac ggcgttgatg aaatgattca
    27481 gggatttgcc gttgctatca aaatgggagc aaccaaggct gactttgatg caactgtggc
    27541 aattcaccca actgcatctg aagaatttgt aaccatgcgt taatcgaaac aaaagaagct
    27601 gatataaata tgtctgcttc ttttttaatg attttcgaat caacaaaaaa attatccaac
    27661 ttgactagtc acgaaaatcg gctgttacag tttttgttac cttgttttta aaaaatggtt
    27721 gacatcgact cctatatgag tataatagtt actatacatt agaaaagagg ttaactattt
    27781 tgaaaaaagc tcacgtttat gctatccctg ctattggggc tgctctcatt gctgttttgg
    27841 cacaaatcag tcttccaatt ggacctgttc ccttcactct gcaaaacttt gcaatcggct
    27901 tgattgctac tgtctttaga ccgagagagg ctgtactttc tgctggactc tatcttcttc
    27961 taggtgctat cggtcttcct gtctttgcag gaggtggagc tggttttcag gctttagttg
    28021 gccctactgc aggctatctt tggttttatc tcgtttactc tggacttact tcctctctaa
    28081 ccaacagcaa gagtggtgtt gttaagattt ttcttgcaaa cctcttgggt gatgcccttg
    28141 tctttgtcgg cgggattctc agcttgcatt tcctagctgg aatggcattt gaaaaagctc
    28201 ttgttgtggg ggttcttccc tttatcattc cagaccttgg caaacttctg gctattagtt
    28261 ttattagccg tcccctactt caacgcctta aaaatcaggc ttactttact aactaaaaaa
    28321 ggataccgag ttatcatgac tcaatatcct tttttttatt ttgaaaactt atactcaatg
    28381 aaaatcaaag agcaaactag gaagctagcc gcaggctgct caaaacactg ttttgaggtt
    28441 gtagatgaaa ctgacgaagt cagtaaccat acggcaaggc aaagctgatg cggtttgaag
    28501 agattttcga agagtattag ttgcctttaa aggcatccac catcgtttga aattcttcat
    28561 ttgagagagt aatccctttg cccattttag tatggtctgg actccaagca cgaatatcaa
    28621 actttgcagg ggcaccatta aagctcacac ggttaatttc cttggtccaa cctttttcgt
    28681 tttcagaaag agtcaacaag tgctcttcga tttcaaatgt aaattctgcc attttcttct
    28741 ccttttttag tttcattagt ttattcgtaa aatcttgtag attttaggaa aattttatat
    28801 aatattgata taaaagaagg gaggccaata tgagacataa attccagcaa gttctagata
    28861 aaatacatga ttttttaaat ggacatgacc aacctgacca gactgaaacc aactccctta
    28921 cagccactat tgaagaggct atccagaaac aaaccgctgt tcaccttatc ttgtctgaga
    28981 caagctttac aggtgatatc atcaaatatg atcagcaagg ccagcaaatt atcgtgaaaa
    29041 attttgccaa aaatgtgagc cggattatcc gtataagcga tattcaacgc ctgcgatttg
    29101 tcccctcaac tgtccaaaca gcccaaaaaa atagatttaa gaaagagtga gatgtagttg
    29161 cttcatccca ctcttttttc ttagcgaatt tgttcaaaat gtaaatgaac tgcgatatga
    29221 tctccataac cacttctttc caagtcacgt tgtaaacgat aggaaatgta gtgttctgca
    29281 atggtaatgt aacctgcgcc caataaacga tgttcaacca tagattgaat catactgata
    29341 gtcgcacgtt ccaccttggc ttcttgtaaa tccaaaacta ccttcttagt gacttgagca
    29401 agattttgac gcaaatcatc tgtcaaaaca taaacagttt gggctgcctt caagatggct
    29461 tggtaaatct tatctggatt aaattcagca atttcgccat tacgtttgat tacttgcata
    29521 ggtttctcct ttattctttg ttttctttga tttctgccag cattttttct tcttctactg
    29581 tcagttgata atgttcaagt aaatccggtc tgcgctcgta ggttttcttt aaactctcgt
    29641 acaatcgcca ctgacgaatc ttttcatggt ggccactcat caatacatct ggcacgacca
    29701 tgcctcgata atcataggga cgtgtgtact gaggatattc taaaagacct gaagaaaaac
    29761 tatcatcttg gtggctagac tccttgccaa tcacttctgg aatcaggcga actgtagcat
    29821 caatcatggt catagctgcc aattctccac cagtgaggac atagtcgcct agggaaatct
    29881 catctgttac caaggtctta atgcgctcat cataaccctc atagtgccca cagataaaga
    29941 ttagctcttc ctcttgagcc aaatcttcag cataagcctg atcaaactgc tttccagcag
    30001 gatcgaggag aataacgcgc ggatttttct tttcaatagc atcaaaggaa tcgaaaatag
    30061 gttgtgctct gagcaacatg ccctgaccgc ctccgtaggg ctcatcatct acatgacggg
    30121 ccttttcagc attttctcga aaattatgat actggatatc caagagccct ttttctcgag
    30181 cctttccaac gattgagtgc tccagtggag aaaacatctc tggaaagagg gttaaaatat
    30241 caatcttcat cgtctaaccc ttctaagatt tccacatcga cccgtttatt tggaatatca
    30301 acattgagaa ccactggtgg gatataaggt aaaagcaaat cacgtttgcc ttttcgtttg
    30361 accacccaga catcattagc acctggttgc aggatttcct tgatggttcc aaccaagcta
    30421 tcaccctcat agacttccaa accgataatc tcgtgatagt aaaattcacc atcgtctagg
    30481 tcattcaaat cttcctcagc gaccttgaga ctgtatccct tgtacttttc gatagtattg
    30541 atatggtaca tatctttgaa tttaataatg tcaaagttct tctgtttacg gtggctagcg
    30601 atggtcactg tttggacaaa ctgatctttt tcatcaaaca aagtcagctc agctcctttt
    30661 ttaaaccgtt cttctgcaaa atccgtcaca gacaatactc gcatctcacc ctgtaatccc
    30721 tgcgtattaa cgattttccc aacattaaag tagttcatct tgtctcctgt aatctccttt
    30781 ttccatctta ttctgacaat tctcgaataa tagccgcaat tttttccgat tctgaccatt
    30841 gtaaataatg gtgattcctt cctaaaatga gtttagtatt ggaagtccaa tattctgatt
    30901 ctctgtactc tttttctcta taagtctgac aaaaaataaa tacagggaca tgagattcta
    30961 tcgacaaatt ctcaaaatct tcctcagtaa tctctccaga tatctgaaat tctggatctt
    31021 gattttccaa ctctaagcct ttttcttgca ttaattccca gattttttta ttcgtttcag
    31081 gactaaatgt tgcttgagtt aagttcttaa aataaagttc aggaccacac tcgtcaatca
    31141 gcctcatctg ctcttccatt tctggataag gattttctga aaaatcagca aacatgactt
    31201 ttttagttgt cggttcaatt gctactaaag tctgacactt aattggtttc tcgagtaatt
    31261 tgcaagctaa aattccactc caactatgtg cacaaagtat atattcagaa attcctaatt
    31321 cttcaagtac ttcataaacc gcatctgcaa gattatctag attttttcca gcttggtcat
    31381 gaatcggact cctacctgtg ttcggaaaat caattgtcaa ataaccaatt gtaggaggag
    31441 gtttttcaag tataagtgaa aaattttcat aacttggtag caaacctgct ccgtttagac
    31501 aaactagcac tttcttttgc tttttataag taacagagag gctaccaatt tctgtagata
    31561 cttcaaacct cttcataaag aaatccactc attctatata atgaattatt aaaaatcctt
    31621 atcctttatt ttatcacgtt ccaaagattt tctcaagttg gaggaagggg acaatatctc
    31681 tactttccct tcaagaatcc ttccaaatca tgtttatgtt ggtaattaac ggctgcggtt
    31741 ttgtctttct caaagatggt tctagttagg tcaatatgct tgatagcagc aatagcgacg
    31801 gtgtagtgaa tgatattagc cagttctatg gcaggttcct cgttcgaatc ctatcccttc
    31861 ttttcgacca gagcgcctat tcaaaacctc ggctacttct ccgacttcct ccactaactt
    31921 cataaagaga ccttcatcag tccgagactg ctgttaatgt tcgagtaagt agtcttggaa
    31981 ttgcctaaac gttcaatctt ttatagtata ttgaaactag aatagtacac ctttacttct
    32041 aaaacattgt tagaaatcga tttgactgtc ctgatcgatt tgtcctgtta ttatttcatt
    32101 ttactatatc ttctattcca cacaaaaaag cgagacatcc gtcccgccct tcttattttt
    32161 cgtcaataac gattcttact tttttgtatt cagttgggac agagtagaca atcgttctta
    32221 tcgcagaaat agtgcgaccc ttacgaccga ttacacgacc cacatcgctt tgatcaagat
    32281 tcaaatgata ttccaaaaat tctggtgtat cctcaatctt gatagttaag gcatctggtt
    32341 gtgaaattaa gggtttcaca atcgcaataa tgagattttc aatcgtatcc atctgtcaac
    32401 ctactttaaa cttattttga gaatttagaa tcgtggaatt ttttcaatac gccttctttt
    32461 gaaaggatgt tacgtactgt gtctgaaggt tgagctccat tagccaacca tgcaagaacg
    32521 cggtcttctt tcaaagttac ttggttttca gcaacaagtg ggttgtaagt tccaactgtt
    32581 tcgatgaaac gtccgtcacg tggtgaacgt gaatctgcta cgttgatacg gtagaaaggt
    32641 tttttcttag aacccatacg agtcaaacgg attttaactg ccatttttaa agtctcattt
    32701 ctttaatttt ttatttcggt gaaatagctg agctatttag cacatgttct attatagcag
    32761 atttctggca ggtgtcaaga aaaaaacttg acagactata aatttcttaa agcatttaga
    32821 aatttgttag aataggaaat aaatgtttga aagatgctat ccgtgaatac tattttagaa
    32881 aaattttata aagaacacca agtcaaaccc ttcatatcgc ctgaacgaga tttggatact
    32941 tggcttctaa gtcccaaacc cgttcccaag cgaaatatgg acttattagc agatgattca
    33001 ctagcaggag atatcatttt actatggaga atccagtttg gtacttttac cactgaaaca
    33061 tgattttaaa aactcccatt cgaatatgat tcaaaattcg cttagaatca atgttttccc
    33121 actttttcaa aaaataaatt ttcatctaat ttaaataact ttcaattaag tgtgaatttt
    33181 gcttaaaatc attaaaaaac accccatggt gtgaaccatg aagtgttgta aatgctgtgt
    33241 tgtagctagt tcttagcgtt tagagaactg gctagcttta cgagctttct taagatctgg
    33301 ttccctaaat actttgagta cacttatggc attgatgccc caaaacatct aaaaactctg
    33361 gtagaaaaag ggtatgctct tgtcgaaact tcttttgact cacttgacca tctaaataat
    33421 accatgaaaa agaatatcct gaagaagaag aagggagtta ctggactttc taaaatgaaa
    33481 tcttgcgacc tggatcaagc ccttcatgag catttttcag aagaagaatt agctggtcac
    33541 tttcatgtcc ttctatggac ttttttacaa tggcattgct atcacaccca atacctatct
    33601 aagcgcctgg ttcgtaaact ttattgcagc tcttcctcta aatttcctaa ttgttgaacc
    33661 aattgcccgt tttatactaa gttcttttca gaaaccattt actggggaag aagttgaaga
    33721 ttttcaagat gatgatgaaa tcccaactat tatctaagcc agttctgtaa actactaata
    33781 tttgaaatcc acttcctttt agggtacaat ggttataaat gaatttttga gaggatcaga
    33841 atgaaaaaac tagcaaccct tcttttactg tctactgtag ccctagctgg gtgtagcagc
    33901 gtccaacgca gtctgcgtgg tgatgattat gttgattcca gtcttgctgc tgaagaaagt
    33961 tccaaagtag ctgcccaatc tgccaaggag ttaaacgatg ctttaacaaa cgaaaacgcc
    34021 aatttcccac aactatctaa ggaagttgct gaagatgaag ccgaagtgat tctccacaca
    34081 agccaaggtg atattcgcat taaactcttc cctaaactcg ctcctctagc ggttgaaaat
    34141 ttcctcactc acgccaaaga aggctactat aacggtatta ccttccaccg tgtcatcgat
    34201 ggctttatgg tccaaactgg agatccaaaa gggaacggta caggtggtca gtccatctgg
    34261 catgacaagg ataagactaa agacaaagga actggtttca agaacgagat tactccttat
    34321 ttgtataaca tccgtggtgc tcttgctatg gctaatactg gtcaaccaaa caccaatggc
    34381 agccagttct tcatcaacca aaactctaca gatacctctt ctaaactccc tacaagcaag
    34441 tatccacaga aaattatcga agcctacaaa gaaggtggaa accctagtct agatggcaaa
    34501 cacccagtct ttggtcaagt gattgacggt atggatgttg tggataagat tgctaaggcc
    34561 gaaaaagatg aaaaagacaa gccaactact gctatcacaa tcgacagcat cgaagtggtg
    34621 aaagactacg attttaaatc ttaaaaacca aaaaaataca gtatccacat tcggtactgt
    34681 atttctttta ctctcattct taagttaaat tattaaaatc ccatatttgg tctatccagc
    34741 cttcataaaa gtctggctcg tggcagacca taaggataga tcccctatat tctttgagag
    34801 cgcgtttgag ctcatccttt gcatccacat ccaaatggtt ggtcggctcg tccagcacta
    34861 aaacgttgtt ttcacgattc atcaagagac agaaacgaac cttggcttgc tctccccctg
    34921 ataatacttg aatctggctt tcaatatgtt tggttgtcaa accacaacgg gcaagggctg
    34981 cacggacttc tgcttgatta agggcaggaa aggcattcca gacagcttca agaggagttt
    35041 ggcgattacc gccttctact tcctgctcaa aataaccaag ttctaaataa tctccacgct
    35101 ccacttcccc agcgattggc gagataatgc ctaagagact cttcaagaga gttgtttttc
    35161 caataccatt agcaccaata atcgcaacct tttgattgcg ttcgaaggta agatttaaag
    35221 gcttagtaag aggacggtcg taaccaattt gcaagttctt ggcttggaag ataaagcgcc
    35281 ctggtgtacg agctggtttg aaatcaaagg atggttttgg tttctcactt tggagttcga
    35341 taatatccat cttatccaat ttcttttgac gagacatagc catattacga gttgcaacac
    35401 gggctttatt acgagccaca aagtccttga ggtctgcaat ctctttctgc tggcgttcgt
    35461 aggctgcctc tagctgagat ttcttcatag cataaacttc ttggaactgg tagtagtcac
    35521 cagagtaacg cgtcagctgt tgattttcca catgatagac aatattaata acgtcattga
    35581 ggaatggaat atcgtgcgaa atgagaacaa aggcattctc atagttttgg agatagcgct
    35641 tgagccaatc aatatgctca gcatccaagt agttggtcgg ctcgtccaac agcaagatat
    35701 caggcttttc aaggagaagt tttgccaaaa gcaccttggt tctttgccca cctgacaaag
    35761 aagttacatc cgtatccatg ccaaagtcca taacaccaag agcacgcgct acttcgtcaa
    35821 tcttagcatc caaggtatag aaatcacgac tctccagacg gtcttgaagt tctcctactt
    35881 cttccatgag agcatcaaca tccgcgccgt cttcagccat tttcatatag aggtcattga
    35941 tacgagcttc agctttaaaa agctcatcaa aagccgtacg gagaacatca cgcaccgact
    36001 gtctttcagc aaggacagag tgctgatcca agtaaccagc cgtcacatat ttggaccact
    36061 caacctttcc ttcatctggc agcattttac cagtcacgat actcataaag gttgattttc
    36121 cttcaccatt ggcaccgacc aggccgatat gttctccctt gaggagacgg aaggacacat
    36181 cttcaaaaat tgcacggtca ccaaaaccgt gactcagatt tttaacttct aaaatactca
    36241 ttttaattcc ttatcttgtt tttatgtaat cgtttataaa ggagccaagc cagatagcca
    36301 cccaaagtgt tggtccacaa atcatcaatc tcaaagacgc gattgaaatc aaagaaaaag
    36361 tccaagatta attgcgtaca ctcgattcca agactcacaa gaaaactaaa aagaaggacc
    36421 ttttttgttt tccgcaaatt tggaaataga taaaggagtt ggaaaatcag aggaaaaaac
    36481 aagaagacat tgaggacatt ttgtaaaaaa atccaacata attgtccaat gtcactcact
    36541 tcgcccagtt tccagagaga attgaaagga gtcaaaagaa aaa
//
LOCUS       DAVHKZ010000019        36014 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000019 DAVHKZ010000000
VERSION     DAVHKZ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.019"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..275)
                     /locus_tag="VVO74_001134"
     CDS             complement(<1..275)
                     /locus_tag="VVO74_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HEU5695161.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLIRRSQWVEVT"
     gene            270..524
                     /locus_tag="VVO74_001135"
     CDS             270..524
                     /locus_tag="VVO74_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU5695162.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            718..2052
                     /gene="trmFO"
                     /locus_tag="VVO74_001136"
     CDS             718..2052
                     /gene="trmFO"
                     /locus_tag="VVO74_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU5695163.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGAGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLSSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            2136..2873
                     /locus_tag="VVO74_001137"
     CDS             2136..2873
                     /locus_tag="VVO74_001137"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU5695164.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQPGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2882..3439
                     /gene="frr"
                     /locus_tag="VVO74_001138"
     CDS             2882..3439
                     /gene="frr"
                     /locus_tag="VVO74_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU5695165.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDIGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKREKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3499..4353
                     /gene="cvfB"
                     /locus_tag="VVO74_001139"
     CDS             3499..4353
                     /gene="cvfB"
                     /locus_tag="VVO74_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU5695166.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4362..4577
                     /locus_tag="VVO74_001140"
     CDS             4362..4577
                     /locus_tag="VVO74_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEU5695167.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEESAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4663..5631
                     /locus_tag="VVO74_001141"
     CDS             4663..5631
                     /locus_tag="VVO74_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU5695168.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            5700..6514
                     /locus_tag="VVO74_001142"
                     /pseudo
     CDS             5700..6514
                     /locus_tag="VVO74_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1515 family transposase"
     gene            complement(6479..6661)
                     /locus_tag="VVO74_001143"
     CDS             complement(6479..6661)
                     /locus_tag="VVO74_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695169.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     RLVRNLVHFIIDDGTN"
     gene            6697..7197
                     /locus_tag="VVO74_001144"
     CDS             6697..7197
                     /locus_tag="VVO74_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5695170.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            7200..7460
                     /locus_tag="VVO74_001145"
                     /pseudo
     CDS             7200..7460
                     /locus_tag="VVO74_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(7827..8926)
                     /gene="ald"
                     /locus_tag="VVO74_001146"
                     /pseudo
     CDS             complement(7827..8926)
                     /gene="ald"
                     /locus_tag="VVO74_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003072563.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            9103..9672
                     /locus_tag="VVO74_001147"
     CDS             9103..9672
                     /locus_tag="VVO74_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5695171.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            9740..10390
                     /locus_tag="VVO74_001148"
     CDS             9740..10390
                     /locus_tag="VVO74_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEU5695172.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDSSTEKEVKKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            10374..12614
                     /locus_tag="VVO74_001149"
     CDS             10374..12614
                     /locus_tag="VVO74_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEU5695173.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMGNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            12793..12981
                     /locus_tag="VVO74_001150"
     CDS             12793..12981
                     /locus_tag="VVO74_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695174.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYARYEVINYYSGGY"
     gene            13014..13601
                     /locus_tag="VVO74_001151"
     CDS             13014..13601
                     /locus_tag="VVO74_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695175.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            13605..14789
                     /locus_tag="VVO74_001152"
                     /pseudo
     CDS             13605..14789
                     /locus_tag="VVO74_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655960.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     misc_feature    14953..15084
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            15100..15630
                     /gene="infC"
                     /locus_tag="VVO74_001153"
     CDS             15100..15630
                     /gene="infC"
                     /locus_tag="VVO74_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU5695176.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            15663..15863
                     /gene="rpmI"
                     /locus_tag="VVO74_001154"
     CDS             15663..15863
                     /gene="rpmI"
                     /locus_tag="VVO74_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU5695177.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            15915..16274
                     /gene="rplT"
                     /locus_tag="VVO74_001155"
     CDS             15915..16274
                     /gene="rplT"
                     /locus_tag="VVO74_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU5695178.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            16332..16712
                     /locus_tag="VVO74_001156"
     CDS             16332..16712
                     /locus_tag="VVO74_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU5695179.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            16962..17762
                     /locus_tag="VVO74_001157"
     CDS             16962..17762
                     /locus_tag="VVO74_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU5695180.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHGRGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            17773..18711
                     /locus_tag="VVO74_001158"
     CDS             17773..18711
                     /locus_tag="VVO74_001158"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU5695181.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPVIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            18753..20786
                     /locus_tag="VVO74_001159"
     CDS             18753..20786
                     /locus_tag="VVO74_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEU5695182.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKEKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFH
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     YSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNKNAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(20847..22502)
                     /gene="pavA"
                     /locus_tag="VVO74_001160"
     CDS             complement(20847..22502)
                     /gene="pavA"
                     /locus_tag="VVO74_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU5695183.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQENKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            22607..23104
                     /gene="ybeY"
                     /locus_tag="VVO74_001161"
     CDS             22607..23104
                     /gene="ybeY"
                     /locus_tag="VVO74_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU5695184.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRNTDRPTDVISLEYKPELEIAFDEEDLLENSELAEMMSEFDAYIGEL
                     FISSDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            23085..23480
                     /locus_tag="VVO74_001162"
     CDS             23085..23480
                     /locus_tag="VVO74_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU5695185.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEILNSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            23497..24396
                     /gene="era"
                     /locus_tag="VVO74_001163"
     CDS             23497..24396
                     /gene="era"
                     /locus_tag="VVO74_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU5695186.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKIPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMLREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            24445..25269
                     /gene="mutM"
                     /locus_tag="VVO74_001164"
     CDS             24445..25269
                     /gene="mutM"
                     /locus_tag="VVO74_001164"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU5695187.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQIHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            25269..25874
                     /locus_tag="VVO74_001165"
     CDS             25269..25874
                     /locus_tag="VVO74_001165"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU5695188.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            25861..27060
                     /locus_tag="VVO74_001166"
     CDS             25861..27060
                     /locus_tag="VVO74_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HEU5695189.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            27060..27209
                     /gene="rpmG"
                     /locus_tag="VVO74_001167"
     CDS             27060..27209
                     /gene="rpmG"
                     /locus_tag="VVO74_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU5695190.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            27249..27482
                     /gene="secG"
                     /locus_tag="VVO74_001168"
     CDS             27249..27482
                     /gene="secG"
                     /locus_tag="VVO74_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU5695191.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            27584..29938
                     /gene="rnr"
                     /locus_tag="VVO74_001169"
     CDS             27584..29938
                     /gene="rnr"
                     /locus_tag="VVO74_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU5695192.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTIIQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            29901..30368
                     /gene="smpB"
                     /locus_tag="VVO74_001170"
     CDS             29901..30368
                     /gene="smpB"
                     /locus_tag="VVO74_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU5695193.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKRQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            30384..31244
                     /gene="tehB"
                     /locus_tag="VVO74_001171"
     CDS             30384..31244
                     /gene="tehB"
                     /locus_tag="VVO74_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU5695194.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMETVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            31317..32270
                     /gene="coiA"
                     /locus_tag="VVO74_001172"
     CDS             31317..32270
                     /gene="coiA"
                     /locus_tag="VVO74_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU5695195.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIQQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            32289..34091
                     /gene="pepF"
                     /locus_tag="VVO74_001173"
     CDS             32289..34091
                     /gene="pepF"
                     /locus_tag="VVO74_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU5695196.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            34093..34806
                     /locus_tag="VVO74_001174"
     CDS             34093..34806
                     /locus_tag="VVO74_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU5695197.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEEFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            34873..35814
                     /gene="prsA"
                     /locus_tag="VVO74_001175"
     CDS             34873..35814
                     /gene="prsA"
                     /locus_tag="VVO74_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU5695198.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(35931..>36014)
                     /locus_tag="VVO74_001176"
     CDS             complement(35931..>36014)
                     /locus_tag="VVO74_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU5695199.1"
                     /translation="IDYYNNKRIKVKLKGLSPVQYRTKSFR"
BASE COUNT        10859 a         6724 c         8083 g        10348 t
ORIGIN      
        1 gttacttcaa cccattggct ccgacggatt aagttgcttt cgtgaatacc aaaatcagcc
       61 gcaatttgtt cataagttcg atattctcgc acatattgaa gagtggccat aagaaggtct
      121 tctaggctta atttaggttt tcgtccacct tttgcgtgtt taagttgata agctgttttt
      181 aatacagcta atatctcttc aaaagtcgtg cgctgaacac caacaagacg cttaaatcgt
      241 gcatcagtta gttgtttact tgcttcatca ttcatagaac tactatacca tattttgttt
      301 cgcaggaagt ctattggaaa gtaagaaata ttgaagctga ggctattaga agaaattgtg
      361 agcgtggtgc tattttttca ggtaaaataa aatatcacga agattcacag tttaaaggag
      421 atcactatgt tgaatgttat gctgttttag ataatacggt tatagcaaga gatagaataa
      481 cagtccctat cgatccgtta tgtggaaaag attttataga gtagcatata attgattctt
      541 aactggaata ctcactatct ctttacatca agaaaatgac taaacaggga agtttgcctt
      601 cttccctttt tttgttatac tagtagaaga aaaaattaga aagatttgtg ggtgtcaaac
      661 agcccagtgg ggtgttttaa tatggactta ggtcccaccc aaagaggtat tagtgtcgtg
      721 tctcaatctt atatcaatgt tatcggtgct ggtttggcag gttctgaagc agcttaccaa
      781 atcgcagagc gtggtattcc agttaaacta tatgaaatgc gtggtgtcaa gtctacaccc
      841 cagcataaaa cagacaattt tgctgagttg gtttgttcca attctttgcg tggggatgct
      901 ttgacaaatg cagttggtct tctcaaggaa gaaatgcgtc gcttgggttc tgttatcttg
      961 gaatctgctg aggctacacg tgttcctgca ggtggtgccc ttgcagtgga ccgtgatggt
     1021 ttctctcaaa tggtgaccga aaaagttgcc aaccacccct tgattgaagt ggttcgtgat
     1081 gaaattacag aattgccgac agatgttatt acggttatcg ctactggtcc tttgacaagt
     1141 gatgccttgg ctgaaaagat tcatgctctt aatgacggtg ctggttttta tttctacgat
     1201 gcggcagcgc ctattatcga tgtcaacact atcgatatga gcaaggtcta cctcaaatca
     1261 cgttatgata agggagaagc ggcctacctc aatgccccta tgaccaagca agaatttatg
     1321 gatttccatg aagctttggt caatgcagaa gaagcaccgc ttagttcttt tgaaaaagaa
     1381 aagtactttg aaggatgtat gcctatcgaa gtcatggcca aacgtggcat taaaactatg
     1441 ctttatggcc ctatgaagcc agtcggtctt gagtacccag acgactatac aggacctcgt
     1501 gatggagaat ttaaaacacc ttatgcggtt gtgcaacttc gtcaggataa tgcagctggt
     1561 agcctctaca atattgttgg tttccagacc cacctcaaat ggggagaaca aaagcgtgtc
     1621 ttccaaatga ttccgggtct tgaaaatgcg gagtttgtcc gttatggtgt gatgcatcgc
     1681 aattcttaca tggattcacc aaatcttctt gagcagactt accgttctaa gaaacaacca
     1741 aatctcttct ttgctggtca aatgacgggt gtggaaggct atgttgagtc ggcggcttca
     1801 ggcttagttg cgggaattaa cgcagctcgt ctcttcaagg aagaaagcga ggctattttc
     1861 cccgagacga cagcgattgg aagcttagct cattacatta cccatgccga cagcaaacat
     1921 ttccaaccaa tgaatgtcaa ttttgggatc atcaaggagt tggaaggcga gcgtatccgt
     1981 gataagaagg ctcgttatga aaaaattgca gagcgtgccc ttgccgactt agaggaattt
     2041 ttgactgtct aatttttttg aaagaattgc tcatgatact ataaaaatct tagaaattgt
     2101 gataaaatag gtaggatgaa agaaggagag tgaaaatggc gaatcccaag tataaacgta
     2161 ttttaatcaa gttatcaggt gaagcccttg ccggtgaacg tggcgtaggg attgatatcc
     2221 aaacagttca aacaatcgca aaagagattc aagaagttca tagcttaggt atcgaaattg
     2281 cccttgttat cggtggagga aatctctggc gtggagaacc tgcagcagaa gcaggtatgg
     2341 accgtgttca ggcagattac acaggaatgc ttgggactgt tatgaatgct cttgtgatgg
     2401 cagattcatt gcaacaagtt ggggttgata cacgtgttca aacagctatt gccatgcaac
     2461 aagtggcaga gccttatgtc cgtggacgtg cccttcgtca ccttgaaaaa ggccgtatcg
     2521 ttatctttgg tgctggaatt ggttcacctt acttctcgac agatacaaca gcggcccttc
     2581 gtgcagctga aatcgaagca gatgccatcc tcatggctaa aaatggtgtc gatggtgttt
     2641 acaatgccga tcctaagaaa gataagacag ctgttaagtt tgaagaattg acccaccgtg
     2701 acgttatcaa taaaggtctt cgtatcatgg actcaacagc ttcaaccctc tcaatggaca
     2761 acgacattga cttggttgta ttcaacatga accaaccagg caacatcaaa cgtgtcgtat
     2821 ttggtgaaaa tatcggaaca acagtttcaa ataatatcga agaaaaggaa taagaaagaa
     2881 tatggctaac gcaattattg aaaaagctaa agagagaatg acccagtctc accaatcact
     2941 tgctcgtgaa tttggtggta tccgtgctgg tcgtgccaat gcaagcttgc ttgaccgtgt
     3001 acatgtagaa tactatggag tcgaaactcc tcttaaccaa atcgcttcaa ttacgattcc
     3061 agaagcgcgt gttttgttgg taacaccatt tgacaagtct tcattgaaag acatcgaacg
     3121 tgccttgaac gcttctgata ttggtatcac accggctaat gacggttctg tgattcgctt
     3181 ggttatccca gctcttacag aagaaactcg tcgtgacctt gctaaagaag tgaagaaggt
     3241 cggcgaaaat gctaaagtgg ctgtccgcaa tatccgtcgc gatgctatgg acgaagctaa
     3301 gaaacgagaa aaagcaaaag aaatcactga agacgaattg aagactcttg aaaaagacat
     3361 tcaaaaagta acagacgatg ctgttaaaca catcgacgac atgactgcta acaaagagaa
     3421 agaacttttg gaagtctaaa aataaacaga aaaactcagt tggcattgct ggctgagttt
     3481 tattcgaaag aaggaaatat gaatacaaat cttgcaagtt ttatcgttgg actgatcatc
     3541 gatgaaaacg accgttttta ctttgtgcaa aaggatggtc aaacctatgc tcttgctaag
     3601 gaagaaggcc aacatacagt aggggatacg gtcaaaggtt ttgcatacac ggatatgaag
     3661 caaaaactcc gcctgacaac cttagaagtg actgccactc aggaccaatt tggttgggga
     3721 cgtgtcacag aggttcgtaa ggacttgggt gtctttgtgg atacaggcct tcctgacaag
     3781 gaaatcgttg tgtcactcga tattctccct gagctcaagg aactctggcc taagaagggc
     3841 gaccaactct acatccgtct tgaagtggat aagaaagacc gtatctgggg cctcttggct
     3901 tatcaagaag acttccaacg tcttgctcgt cctgcctaca acaacatgca gaaccaaaac
     3961 tggccagcca ttgtttaccg tctcaagctg tcaggaactt ttgtttacct accagaaaat
     4021 aatatgcttg gttttattca tcctagcgag cgttacgcag agccacgttt ggggcaagta
     4081 ttagatgcgc gcgttattgg tttccgtgaa gtggaccgca ctctgaacct ctccctcaaa
     4141 ccacgctcct ttgaaatgtt ggaaaacgat gctcagatga ttttgactta tttggaaagc
     4201 aatggcggtt tcatgacctt aaatgacaag tcatctccag acgacatcaa ggcaaccttt
     4261 ggcatttcta aaggtcagtt caagaaagct ttaggtggtc ttatgaaggc tggtaaaatc
     4321 aagcaggacc agtttgggac agagttgatt tagggaggct tatgagaaaa tcattttaca
     4381 cttggctcat gaccgagcgc aatcctaaaa gtaacagtcc caaagcaatt ttggcagacc
     4441 tcgcttttga agagtcagcc tttccaaaac acacagatga ttttgatgag gtcagtcgct
     4501 ttttggagga gcatgccagt ttctctttta acctaggaga ttttgacagc atttggcagg
     4561 aatatctaga acactagcat ttattcattg ggtttgggct agtaatttct ccatccctct
     4621 gctataataa aaagaaataa aaggattaga gaggttcttt atttgaagga acattcaata
     4681 gacattcaac tgagtcatcc agatgacctg tttcatcttt ttggttccaa tgaacgccat
     4741 cttcgtttga tggaagaaga gcttgatgtt gtgattcatg ctcgtacgga gattgtccag
     4801 gttttgggag aagagtctgc ctgtgaggaa gcccgtcaag ttattcaggc tttgatggtc
     4861 ttggtaaatc gtgggatgac cgttggtacg ccagatgtag tcactgcgat tagcatggtc
     4921 aaaaatgatg aaattgacaa gtttgtcgcc ctttacgaag aagaaattat caaagataat
     4981 actgggaaac ctatccgtgt caaaacccta gggcaaaagc tttatgtgga cagtgtcaaa
     5041 cagcatgatg tgacctttgg aattgggcca gcaggtacag ggaagacctt ccttgcagtg
     5101 accttggcag tgactgccct taaacgtggg caagtcaagc gaattatcct aactcgtcca
     5161 gcggtggaag cgggagagag tcttggattt cttccgggtg atcttaagga gaaggtggat
     5221 ccttaccttc gtcctgttta cgatgccttg tatcaaattc ttgggaaaga ccaaacgact
     5281 cgtctcatgg agcgtgaaat tatcgaaatt gcgccccttg cctatatgcg tggccggacc
     5341 ttggatgatg cctttgtcat tctcgatgag gcgcaaaaca cgaccatcat gcagatgaag
     5401 atgttcttga cgcgtttagg ttttcattct aagatgattg tcaatggaga tattagtcag
     5461 attgacctgc cacgtaatgt caagtccggt ttgattgatg ctcaagagaa actcaagaac
     5521 atccatcaga ttgactttgt tcatttttca gccaaggatg tggttcgcca tcctgttgtc
     5581 gctcagatta tccgagccta tgaatattct actgaagttg cacacgactg attttgagga
     5641 agttcgcctg caaaagaata gacttgttcg gtaactgtaa aaagtgttat actattttta
     5701 tggaaacagt atacgacaaa gcacaaaaac ttaactcaaa aaacttcaaa ctattgattg
     5761 gtgtcaaaaa ggaaaccttt caactcatgc tagaacacct gaattcagcc tatcagattc
     5821 agcaccgaaa aggtggacgt ccacgtagtc tgcccatgga agaccagctc attatgaccc
     5881 tccgttactt gcgatattat cccactcagc gtctgctggc ctttgatttt ggcgtcggtg
     5941 tagctacggt aaatgccatc atcacttggg tggaggatac acttcgtgcg tcaggtagct
     6001 ttgatttgga ccatttagaa gccccgagtg ctgctgtggc tattgacgtg accgaaagtc
     6061 cgattcagcg tccaaacaaa accaaagcaa aaattattct ggtaaaaaga aacgacacac
     6121 cttaaaaact caaattatgc tggatttgac gacacataaa gtctgtcaaa tggccttttc
     6181 tgacggacat acgcatgatt ttactctctt caaagaaagt attggacaaa gtttgcctga
     6241 aacgacgctt gcctttgttg acctaggtta tttaggcatc ttgaaatttc atgagaatac
     6301 tttcattcct gctaaaaatt ccaaaaatcg ccgcctgagt gaggatgata agcagttaaa
     6361 taaagagatg tcagcgatac gaattgaaat tgaacatttt aacgctaaat tcaagacctt
     6421 ccaaatcatg tcagtccctt atcgtaaccg cagaaaacgt ttcgagttac gggcggaatt
     6481 aatttgtgcc atcatcaatt atgaagtgaa ctagattccg aacaagtcta atatactttt
     6541 gagagaggaa aatccagttg tataggctaa aggttttatc caaaggtctg agacaacgat
     6601 taggcacgat ggaaagaact tttatgtggc tgatgacgat cagtgcatct tcctgtgtca
     6661 taatcacagg gcacaagaaa gtaggaattt gaaaagatga ttgaccaact atctaagtat
     6721 tacagttgta ggatactaac tgaaaaggat attccaagta ttttatcttt atatgaaagt
     6781 aatcctctgt attttcagca ttgtccacca gagccaaatt ttgcaactgt aaaagaggac
     6841 atgctttgtc tacctgaagg taaagctaag gctgataagt tttttgttgg attttggaat
     6901 ggatctgacc ttgtggctgt tatggatttt gtctatgcat atcctgatga ggagactgtt
     6961 tttattggtt tgtttatggt tgatcaagcc tatcagagaa aagggattgg tagtcatatt
     7021 gtgacagaag cactagctta ttttgctaag aactttcgaa aggcacgttt ggcttatgtt
     7081 aagggaaatc cgcaatctca gcatttttgg gaaaagcagg gctttaaatc aattggatgc
     7141 gaggttaagc aagaactcta tacggttgtt atcgctgaac agagcctaga agattagaaa
     7201 tggcatcaag taagaactat ttggaatttg ttttggaaca attatcagga ttagatgatg
     7261 tgacttaccg ttccatgatg ggggagtata ttctttactt ccgcggcaag attattggcg
     7321 gcatttatga cgatcgcttt ttagttaaac ccgtgcaagc agtcttagat aagattgacc
     7381 aatcttcttt tgagtttcca tacaaaggtg ccaaagaaat gatttgagtg gaagaacttg
     7441 ataataagat gtttctataa gacctaattt tagctatgta taaccaactg ccaacgccca
     7501 aacctaaaaa gaaaaagcaa gggtgaacga agtaaaaaag aagtctgcta aggccctgtc
     7561 tttgcacggg taaaatttta tatataaaaa gaagctggga ctaaagagct cagcttcctt
     7621 tggtttatat aattgtcatt acaagacgaa gtggttgggc gaaactctgt tgactttatt
     7681 caatttagag tttcttatgc acaattgagt ctggaacgaa agtctccagt tgcaaagtat
     7741 acagtacaat aaaccaacga tgtaatagct gatgacacaa agcacagtgg gtaggacttg
     7801 cgaagtcacc cttttctttt caaaatttat actaaatcat tgatatcagt gtagtcacga
     7861 ttaagtcctt gagcaactgg taggttagtc aagtaacctt gataagtagt cacaccttga
     7921 cgcaagcctt catcttcaga gattgcttgt gcgaatcctt tgccagccaa agcttcgata
     7981 taaggaagag tgacattggt tagggcgatg gttgaagtgc gagcaaccgc accagggata
     8041 ttggcaacgg catagtggag aacaccgtgt ttttcataga cgggttcatc gtgcgttgtc
     8101 acacggtcag ctgtttcgat aacgccacct tggtcaacag caacgtcaac gatacagagc
     8161 ctggacgcat ttgtttgacc atctcatctg tcaccaattc cggtgctttt gcaccaggga
     8221 tgagaatggc tccaatcacc acatcagcat ctctcacact tgcttcaatg ttgaatgaat
     8281 tagacataag agtttgaatt tgacttccaa agacttcttc tagaactgag agacgcttgg
     8341 aactaatatc taaaatagtc acttgagcac caagaccaag ggcgatgcgg gcagcatgtg
     8401 taccgacgac accaccaccg atgatagtta cttttccttt tggaacacct ggtacaccac
     8461 caagtagaac accagagcca ccagcttgct tagtaaggaa gtgagctccg atttgaacag
     8521 ccatacgacc tgcaacctca ctcataggaa cgaggagcgg tagttgtcct tgattgtcac
     8581 gaacagtttc agttgttttt gctgttaaca tagcatctgc taattctgga gcagcggcca
     8641 tgtgcaagta ggtgaagaga agaagatcgt cgcgcaagta accgtattca gaacttaaag
     8701 attcttttac tttcacaacc aactctgctg cccaagcttc accagcagta gcgacaatct
     8761 cagctccttg cttttgatag tcagcatcag taaagccaga accgagacca gcatttgttt
     8821 cgataaggac acgatgacca cgactaacta agctatgaac acctgcaggt gtgagggcga
     8881 cacggttttc gttattttta atttcttttg ggattccgat taacattgag ataacctacc
     8941 tttcaattga cggtcttgtt ttggttgtca cattccagtt cataaatcaa aaatgtgacg
     9001 gtttcattgt atatgaaacc gcttcaaaaa tcaagaaaaa cttgtcatcc aaattttttt
     9061 atgctagact agtgaaaatc aagctctaat ggagggaaaa gtatggaatc aatatttgtg
     9121 aaatttgccc agtatccgtc tatagaaacg gagcgtttat tgctcagacc tgtaactttg
     9181 gatgatgcgg aagcaatgtt tgactatgcc tcggacaagg gtaatacacg ttacactttt
     9241 ccaaccaatc aaagcttgga agaaaccaag aataacattg ctcagttcta cttggctaat
     9301 cccttgggac gttggggaat agaactaaaa agcaatggtc agtttattgg aaccattgac
     9361 ttgcacaaga ttgattctgt tcttaagaag gcagctattg gctacattat caataaaaag
     9421 tattggaatc aaggattaac gacagaagcc aatcgtgctg tgattgagct agcttttgag
     9481 aagataggga tgaataagtt gactgccctt cacgataagg ctaatcccgc gtcaggaaag
     9541 gtcatggaga aatcaggcat gcgtttttcc catgcagaac catatgcttg tatggaccag
     9601 catgaaaaag gccgaatcgt gacaagagtt cattatgtct tgaccaagga agactatttt
     9661 gcaaataaat aagcagttga aaagaaattt ttcgactgtt ttttcttcct cttacgaata
     9721 atctaagaga ggagaaaata tggaagcaat tatcgagaaa atcaaagagt ataaaatcat
     9781 cgtcatctgt actggtctgg gcttgcttgt aggaggattt ttcctgctaa aaccagctcc
     9841 acaaacacct gtcaaagaga cgaatttgca ggctgaagtt gcagctgttt ccaaggactc
     9901 atcgaccgaa aaggaagtga agaaggaaga aaaggaagaa ccccttgaac aagatctaat
     9961 cacagtagat gtcaaaggtg ctgtcaaatc gccagggatt tatgacttgc ctgtaggtag
    10021 tcgagtcaat gatgctgttc agaaggctgg tggcttgaca gagcaagcag acagcaagtc
    10081 gctcaatcta gctcagaaag ttagtgatga ggctctggtt tacgttccta ctaagggaga
    10141 agaagcagtt agtcaacaga ctggttcggg gacagcttct tcaacaagca aggaaaagaa
    10201 ggtcaatctc aacaaggcca gtctggaaga actcaagcag gtcaagggac tgggaggaaa
    10261 acgagctcag gacattattg accatcgtga ggcaaatggc aagttcaagt cagtagacga
    10321 gctcaagaag gtctctggca ttggtggcaa aacaatagaa aagcttaaag actatgttac
    10381 agtggattaa gaatttctct attcccctaa tttacctgag ttttctatta ctttggcttt
    10441 attacgctat tttctcagca tcttatcttg ctttgttggg ctttgttttt ctgctagtct
    10501 gtctctttat ccaatttccg tggaaatctg ctggtaaagt tctaataatt tgcggaatct
    10561 ttggattttg gtttgttttt caaaattggc aacagagtca agcgagtcaa aatctggcgg
    10621 attctgttga aagggtacgg attttgcctg atactattaa ggttaatggt gatagtctat
    10681 cctttcgtgg caagtctaac ggtcgtgctt tccaagtcta ttataaactc cagtccgagg
    10741 aggagaaaga agcctttcaa gctttaactg acctgcatga gataggacta gaagggaagc
    10801 tttcggagcc agaagggcag agaaattttg gtggctttaa ttaccaagcc tatctgaaga
    10861 ctcagggaat ttaccagact ctcaatatca aaacaatcca gtcacttcaa aagattggca
    10921 gttgggatat aggagaaaac ttgtccagtt tacgtcgaaa ggctgtggtt tggattaaga
    10981 cgcactttcc agaccctatg ggcaattaca tgacaggact cttgctggga catctggaca
    11041 ccgactttga ggagatgaat gagctttatt ccagtctagg aattatccac ctctttgccc
    11101 tatctggcat gcaggtaggt tttttcatga atggatttaa gaaacttctc ttgcgattgg
    11161 gcttgaccca agaaaagttg aaatggctga cttatccctt ttcccttatc tatgcgggac
    11221 taactggatt ttcagcatcg gttattcgca gtctcttgca aaagctactg gctcaacatg
    11281 gggttaaggg cttggataat tttgccttga cggtgcttgt cctctttatt gtcatgccaa
    11341 actttttctt gacagcagga ggagtcttgt cctgcgctta tgcttttatc ctgaccatga
    11401 ccagcaaaga aggggagggg ctcaaggctg ttactagtga aagtctagtc atctccttgg
    11461 gcatattgcc cattctatcc ttctattttg cggaatttca accttggtct atccttttga
    11521 cctttgtctt ttcctttctt tttgacttgg tcttcttacc gctcttgtct atcttatttg
    11581 tcctttcctt tctctatcca gtcattcagc tgaactttat ctttgaatgg ttagagggca
    11641 ttattcgctt ggtctcgcag gtggcaagga gaccacttgt ctttggtcaa cccaacgcat
    11701 ggcttttaat cttattgtta atttccttgg ctttggtcta tgatttgagg aaaaacatta
    11761 aaggattaac agtattgagt ttattgatta caggtctctt tttccttacc aagtatccac
    11821 tggaaaatga aatcaccatg ctggatgtgg ggcaaggaga aagtattttc ctacgggatg
    11881 taactgggaa aaccattctc atagatgtag gtggtaaggc agaatcttat aagaaaatca
    11941 aaaaatggca agaaaagatg acgaccagca atgcccagcg aaccttgatt ccctatctca
    12001 aaagtcgagg agtagctaag attgaccagc taattttgac taacacggac aaggagcatg
    12061 ttggagattt gtcagagatg accaaggctt tccatgtagg ggagattcta gtatcaaaag
    12121 acagtctgaa acagaaggaa tttgtggcag aactacaggc gactcaaaca aaggtgcgta
    12181 gtatgatagt aggggagaac ttgcccattt ttggaagtca gttagaagtt ctatctccaa
    12241 ggaaaatggg agatggagga cacgatgata ccctagttct gtatgggaaa ttcttggata
    12301 agcaatttct cttcacggga aatttggagg agaaaggaga gaaggacttg ctgaagcact
    12361 atccagactt gaaagtaaat gttttgaaag ctagccaaca tggcaataaa aaatcatcaa
    12421 gtccagcctt tctagaaaaa ctcaaaccag agcttactct tatctcagtt ggaaagagca
    12481 atcgaatgaa actcccccat caggaaacat tgacacgact ggaaggtatc aatagcaaag
    12541 tttatcgaac tgaccagcaa ggagctatac gttttaaggg gttggatagt tggaaaatcg
    12601 aaagtgttcg ataggaagga taaatgttgt agattagtga aataaactaa aaatttgttg
    12661 cataataatg ataaaaatgg tataatgaaa acgtattcaa tattgaggat ataaaatcat
    12721 taaaaatcag caaaagttgt tttattagtt agtttataat ctattggtct tcttcagtcc
    12781 agtgtatctg ctgtgacagt cactaaaagt tacaagtatg attggaatac ggtttgggaa
    12841 tatagtacca actatcacga ccatcagtat gcttggattc cgtcatggtc tcgttatgac
    12901 agctattctg agtataaagt tggcggaggc tggaactacg ctcgttatga ggtcataaac
    12961 tattacagcg gaggctatta attcttaaag agtgagaaaa aggagggcta gatatgttgc
    13021 agcttactca tgtgacctta aaaacgcgac aagtcatctt gcaagatgtg gatttcacct
    13081 ttaaaaaggg tagggtttat ggtcttcttg ctatcaatgg ctctggaaag acgaccctgt
    13141 tccgtgccat tagcaattta attcccataa gtagtggaaa tatcgcagcc cctccttctt
    13201 tattttatta tgagagtatt gaatggctgg atggaaactt aagtgggatg gactaccttc
    13261 gtcttatcaa aaacatctgg aagtcaggtc tgaacttgag ggatgaaatc gcctattggg
    13321 aaatgtctga ctatatcagt cttcccattc gcaagtattc cttaggcatg aagcaacgct
    13381 tggtgattgc catgtatttc ctcagtcagg ccaaatgctg gctcatggat gagattacaa
    13441 atggcttaga tgagtattat cgacagaagt tttttgatag gctagcacaa atcgatagac
    13501 aagaacagct ggttctttta agttcccact ataaggaaga gttggttgat gtctgcgata
    13561 gagtagtaac cattcatcag gggcagatag aagaggttta gtttatgaaa gatgttagtc
    13621 tatttttatt gaaaaaagtt ttcaaaagcc gcttaaactg gattgtctta gctttatttg
    13681 tatctgtact cggtgttacc ttttatttaa atagtcagac tgcaaactca cacagcttgg
    13741 agagcaggtt ggaaagtcgc attgcagcca acgagagggc tatcaatgaa aatgaagaga
    13801 aactctccca aatgtctgat accagctcgg aggaatacca gtttgctaaa aataatttag
    13861 acgtgcaaaa aaatcttttg acgcgaaaga cagaaattct gactttatta aaagaagggc
    13921 gctggaaata agcctactat ttgcagtggc aagatgaaga gaagaattat gaatttgtat
    13981 caaatgaccc gactgctagc cctggcttaa aaatgggggt tgaccgcgaa cggaagattt
    14041 accaagccct gtatcccttg aacataaaag cacatacttt ggagtttccg acccacggga
    14101 ttgatcagat tgtctggatt ttagaggtta tcatcccaag tttgtttgtg gttgctatta
    14161 tttttatgct aacacaacta tttgcagaaa gatatcaaaa tcatctggac acagctcact
    14221 tatatcctgt ttcaaaagtg acatttgcaa tatcctctct tggagttgga gtgggatatg
    14281 taactgtgct gtttatcgga atctgtggct tttcttttct agtgggaagt ctgataagtg
    14341 gttttggaca gttagattat ccctacccaa tttatagctt agtgaatcaa gaagtaacta
    14401 ttgggaaaat acaagatgta ttatttcctg gcttgctctt agctttctta gcctttatcg
    14461 tcattgtgga agttgtgtac ttgattgctt actttttcaa gcaaaaaatg cctgtcctct
    14521 ttctttcact cattgggatt gttggcttat tgtttggtat ccaaaccatt cagcctcttc
    14581 aaaggattgc acatctgatt ccctttactt acttgcgttc agtggagatt ttatctggaa
    14641 gattacctaa gcagattgat aatgtcgatc taaattggag catgggaatg gtcttacttc
    14701 cttgcctgat tatctttttg ctattgggaa ttctatttat tgaaagatgg ggaagttcac
    14761 agaaaaaaga attttttaat agattctagc tttcctatag gtagggaaaa taagtaaaaa
    14821 ctaacataga gagggaatca acttgattct ctctttttga ttcgaaaacc aaaccaaaat
    14881 acaaacacaa acttttcaaa aaataacttt ttatcttgac aagagctaga aaacttggta
    14941 tcatataaaa gttgagaaaa gcagaagtga gagcttctcg ccttgtgaca ttaagttgcc
    15001 tggccctacg gatgaaaagt ttcgaagaaa cgctatcata acgtgcgggc ttgtatattt
    15061 acaagtccgc tattgttttt ctctaataaa acaaaagagg tgaaaaccat agcaaagcaa
    15121 gacttattca tcaatgatga gattcgtgta cgtgaagttc gcttgattgg tcttgaagga
    15181 gaacagctag gtatcaagcc actcagtgaa gcgcaagctt tggctgataa cgctaatgtt
    15241 gacctagtat tgattcaacc ccaagccaaa ccgcctgttg caaaaattat ggactacggt
    15301 aagttcaaat ttgagtacca gaagaagcaa aaagaacaac gtaaaaaaca aagcgttgtt
    15361 actgtgaaag aagttcgtct aagtccaaca attgacaagg gtgactttga tacaaaactt
    15421 cgtaatgcac gtaagttcct tgaaaaagga aataaagtta aggtatctat tcgctttaag
    15481 ggtcgtatga ttacccataa agagattggt gcaaaagttt tagccgagtt tgctgaagca
    15541 actcaagata ttgccatcat cgaacaacgt gctaaaatgg atggacgtca aatgttcatg
    15601 caattggcgc cagcgactga caaaaaataa ttgtcagaaa gttaaataaa ggagaaaaaa
    15661 tcatgccaaa acaaaaaaca caccgcgcat cagctaaacg tttcaaacgt acaggttctg
    15721 gtggacttaa acgtttccgt gcttacactt ctcaccgttt ccacggaaaa actaagaaac
    15781 aacgtcgtca tcttcgtaaa gcatctatgg tgcattcagg agattacaaa cgtatcaaag
    15841 caatgcttac tcgcttgaaa taatagcttg actgtaagta aacaattcta ggaaatattt
    15901 ggaggaaata aaacatggca cgtgttaaag gtggcgttgt atcacgcaaa cgtcgtaaac
    15961 gtattcttaa attagcaaaa ggttactatg gagctaaaca catcttgttc cgtactgcaa
    16021 aagaacaagt aatgaactct tactactatg cataccgtga ccgtcgtcag aaaaaacgtg
    16081 acttccgcaa attgtggatc actcgtatca atgcggcagc tcgtatgaac ggactttcat
    16141 actcacaatt gatgcatggt ttgaaattgg ctgagatcga agttaaccgt aaaatgcttg
    16201 ctgacttggc tgttaacgat gcagtagctt tcacagctct tgcagatgca gctaaagcaa
    16261 aacttggtaa ataacaactg atgagactgg aacaggattg tccagtcttt ttaaaaataa
    16321 aggagaaaag tatggcttca aaaatgctac acacttgctt acgagtagaa aatcttgaaa
    16381 aatcaattgc attctatcaa gatgcttttg gttttaaaga attgcgtcgc agagattttc
    16441 cagaccatgc cttcacgatt gtctatctag gtcttgaggg tgatgattat gagttggagt
    16501 tgacttataa ctacgatcac ggtccgtatg tggttggtga tgggtttgcc catatcgccc
    16561 tcagtacacc tgatcttgag gcacttcatc aagaacacag tgcaaaaggc tatgaagtga
    16621 ctgagccaaa tggtctacca ggaactacac caaactatta ctttgtcaaa gaccctgatg
    16681 gatataaggt cgaagtcatt cgtgaaaaat aatttcgtgc aagttaagta gaatattcgt
    16741 tttctacttg acttttttta gctgaaagag tatactaata aaaattcaac ctttaagggg
    16801 agtccagaga gactcacaag gtgtcagata aaagaatagt gcaattttct agaggagact
    16861 ttttgagtgt gctctcttgt gttgtacgat tttaactgag gccttgcact agcaaggtct
    16921 tttctttatc tggtcccctt aaaatttaag gaggaaaagt tatgaatccc acatgtaaga
    16981 agcgtttggg tgtcattcgg ttggaaacca tgaaggtggt tgcacaagag gaaatcgcgc
    17041 cagcaatctt tgaattagtt ctagaaggag aaatggttga agccatgcga gcaggccaat
    17101 ttcttcatct gcgtgtaccg gacgatgccc atctcttacg tcgtcctatt tcaatttcgt
    17161 ctattgacaa ggcaaacaag cagtgtcacc tcatttatcg gattgaggga gctgggactg
    17221 caattttttc aaccttaagt cagggagaca ctcttgatgt gatggggcct cagggaaatg
    17281 gttttgactt gtctgacctt gatgagcaga atcaggttct ccttgttggt ggtgggattg
    17341 gtgttccacc cttgcttgag gtggccaagg aattgcatgg acgtggagtg aaagtagtga
    17401 cagtcctcgg ttttgctaat aaggatgctg ttattttgaa aacggaattg gctcagtatg
    17461 gtcaggtctt tgtaacgaca gatgatggtt cttatggcat caagggaaat gtttccgttg
    17521 ttatcaatga tttagatagt cagtttgatg ctgtttactc gtgtggggct ccaggaatga
    17581 tgaagtatat caatcaaacc tttgatgatc acccaagagc ctatttatct ctggaatctc
    17641 gtatggcttg tgggatggga gcttgctatg cctgtgttct aaaagtacca gaaagcgaga
    17701 cggtcagcca acgcgtctgt gaagatggtc ctgttttccg cacaggaaca gttgtattat
    17761 aaggagaaaa ttatgactac aaatcgatta caagtgtctc tacctggttt ggatttgaaa
    17821 aatccgatta ttccagcatc aggctgtttt ggctttggac aagagtatgc caagtactat
    17881 gatttagacc ttttaggttc tattatgatc aaggcgacaa cccttgaacc acgttttggg
    17941 aatccaactc caagagtggc agagacgcct gctggtatgc tcaatgcaat tggcttgcaa
    18001 aatcctggtt tagaggttgt tttggctgaa aagctacctt ggctggaaag agaatatcca
    18061 aatcttccta ttattgccaa tgtagctggt ttttcaaaac aagagtatgc agctgtttct
    18121 catgggattt ccaaggcaac taatgtaaaa gctatcgagc tcaatatttc ttgtcccaat
    18181 gttgaccact gtaatcatgg acttttgatt ggtcaagatc cagatttggc ttatgatgtg
    18241 gtgaaagcag ctgtggaagc ctcagaagtg ccagtttatg tcaaattaac cccgagtgtg
    18301 accgatatcg ttactgtcgc aaaagctgca gaagatgcgg gagcaagtgg cttgaccatg
    18361 atcaatactc tggttggaat gcgctttgac ctcaaaacca gaaaaccaat cttggccaat
    18421 ggaacaggtg gaatgtcagg tccagcagtc tttccagtag ccctcaaact catccgccaa
    18481 gtagcccaaa caacagacct gcctatcatt ggaatggggg gagtggattc ggctgaagct
    18541 gccctagaaa tgtatctggc tggggcatct gctatcggag ttggaacagc taactttacc
    18601 aatccttatg cctgtcctgt catcatcgaa aatttaccaa aagtcatgga taaatacggt
    18661 attagcagtc tggaagaact ccgtcaggaa gtaaaagagt ctctgaggta aactgcaatc
    18721 aatctgttct tgatttttta ttagtttgta atatgaattt aggagaattt tggtacaata
    18781 aaataaataa gaacagagga agaaggttaa tgaagaaagt aagatttatt tttttagctc
    18841 tgctattttt cttagctagt ccagagggtg caatggctag tgatggtact tggcaaggaa
    18901 aacagtatct gaaagaagat ggcagtcaag cagcgaatga gtgggttttt gatactcatt
    18961 atcaatcttg gttctatata aaagcagatg ctaactatgc tgaaaatgaa tggctaaagc
    19021 aaggtgacga ctatttttac ctcaaatctg gtggctatat ggccaaatca gaatgggtag
    19081 aagacaaggg agccttttat tatcttgacc aagatggaaa gatgaaaaga aatgcttggg
    19141 taggaacttc ctatgttggt gcaacaggtg ccaaagtaat agaagactgg gtctatgatt
    19201 ctcaatacga tgcttggttt tatatcaaag cagatggaca gcacgcagag aaagaatggc
    19261 tccaaattaa agagaaggac tattatttca aatccggtgg ttatctactg acaagtcagt
    19321 ggattaatca agcttatgtg aatgctagtg gtgccaaagt acagcaaggt tggctttttg
    19381 acaaacaata ccaatcttgg tttcacatca aagaaaatgg aaactatgct gataaagaat
    19441 ggattttcga gaatggtcac tattattatc taaaatccgg tggctacatg gcagccaatg
    19501 aatggatttg ggataaggaa tcttggtttt acctcaagtt tgatgggaaa atagctgaaa
    19561 aagaatgggt ctacgattct tatagtcaag cttggtacta cttcaaatcc ggtggttaca
    19621 tgacagccaa tgaatggatt tgggataagg aatcttggtt ttatctcaaa tctgatggga
    19681 aaatagctga aaaagaatgg gtctacgatt ctcatagtca agcttggtac tacttcaaat
    19741 ctggtggtta catgacagcc aatgaatgga tttgggataa ggaatcttgg ttttacctca
    19801 agtctgatgg caaaatggct gaaaaagaat gggtctacga ttctcatagt caagcctggt
    19861 actacttcaa atctggtggc tacatggcga aaaatgagac agtagatggt tatcagcttg
    19921 gaagcgatgg taaatggctt ggaggaaaag ctacaaataa aaatgctgct tactatcaag
    19981 tagtgcctgt cacagccaat gtttatgatt cagatggtga aaagctttcc tatatatcgc
    20041 aaggtagtgt cgtatggcta gataaggata gaaaaagtga tgacaagcgc ttggctatta
    20101 ctatttctgg tttgtcaggc tatatgaaaa cagaagattt acaagcgcta gatgctagta
    20161 aggactttat cccttattat gagagtgatg gccaccgttt ttatcactat gtggctcaga
    20221 atgctagtat cccagtagct tctcatcttt ctgatatgga agtaggcaag aaatattatt
    20281 cggcagatgg cctgcatttt gatggtttta agcttgagaa tcccttcctt ttcaaagatt
    20341 taacagaggc tacaaactac agtgctgaag aattggataa ggtatttagt ttgctaaaca
    20401 ttaacaatag ccttttggag aacaagggcg ctacttttaa ggaagccgaa gaacattacc
    20461 atatcaatgc cctttatctc cttgcccata gtgccctaga aagtaactgg ggaagaagta
    20521 aaattgccaa agataagaat aatttctttg gcattacagc ctatgatacg accccttacc
    20581 tttctgccaa gacatttgat gatgtggata agggaatttt aggtgcaacc aagtggatta
    20641 aggaaaatta tatcgatagg ggaagaactt tccttggaaa caaggcttct ggtatgaatg
    20701 tggaatatgc ttcagaccct tattggggcg aaaaaattgc tagtgtgatg atgaaaatca
    20761 atgagaaact aggtggcaaa gattagtact ataagtgaat atgatttgag tgaatagtaa
    20821 gttaaaaatc ctgatttcaa gtaaaatcag gattttttca tggatgcaat ttttttggag
    20881 tctggtgtga cgcggagggt cttttgtcct gtgtaagtga caaagccggg ttttccacca
    20941 gttggtttat tgagtttttt gacttcaatc atatctacct gcaccagatt cgacaggcgc
    21001 ccttgagaga agtaggcagc taactctgct gcgtctgtct tgactgcatc agatgggtca
    21061 agatttcctg agatgacaac atggcttcca ggaatgtcct tagcatggaa ccaaagttcc
    21121 tccttgcggg ccattttaaa ggtcaattcc tcattttgaa gattgtttcg tccgacatag
    21181 atgatggttt tgccatcgct tgctagatat tgttctagtt ttttgcgttt ctggattttc
    21241 tcccgttgtc ttctgcggat aaaacctgtt tgaatcaatt cttcacggat ttcagcgatt
    21301 tcttccagtc cagcttggtt gaggacggtt tctacacttt ccagatagag aatagtggct
    21361 ttggtttctt caatcaaatc agtcaagtat ttgacagctt ctttgagttt ctgataccgt
    21421 ttaaaatagc gttgggcatt ctggttggga gtcagagcct tatcaagcgc aatcatgata
    21481 ggttggttgg tatagtagtt gtctaggata acctggtctt ggtcgttagg cacttggtgg
    21541 aggaaggttg tcagcaattc tcctttttga cgaaattctt cagcgttgtc tgtcgccagt
    21601 aactcttttt cctgtttttt gagtttgtgt cggtttttct gaagttcatt ttcaacacga
    21661 cgaatcagtt cactggcctg ctgtttgacg cggtcgcgct cagccttatc cttatagtag
    21721 gtgtccaaca aatcagaaag atttgcaaaa ggctctccca cctgatttgc aaaaggaact
    21781 ggactgaagg aagtctcagt caagcatggc ttgttttctt gattgaaaaa atttcggaaa
    21841 gcggaaagtt tttcactaac cagtatcctt tccaattcat ttgccgtatc gcgtcccaga
    21901 ccttgaaaga ggctttgaag attttttgct gttagttctt gggtttgcag gatttcaaag
    21961 agcttttcat ccttgatagt aaaaggattg agagattctg tacttggcgg agcgatatag
    22021 gtcgatcctg gaagtaaggt gcggtagcta ttttgtgaaa aaccgacgtg tttgataact
    22081 tcgaggattt tatgactgct tttatcgacc agtagaatat tactgtgttt ccccataatt
    22141 tcaataatca aggtagcctg gatatggtct ccaatctcgt ttttattgga aactgtaatt
    22201 tccacaatac ggtcattttc cacttgctca atcgactcaa tcagggcccc ctgcaaatac
    22261 tttctcaaaa ccatgataaa ggtagaaggt tgagctggat tttcaaaagt cgtttgggtc
    22321 agctgaatgc gtccaaaaac tggatgggca gaaaggagca ggcgatggct ttggcgattg
    22381 ctgcggattt gcaagaccaa ctcttgttca aaaggctgat tgattttctg gatgcgacca
    22441 ttcactaatt cgcttcgcaa ttcctcaact atgtggtgta aaaaaaatcc gtcaaatgac
    22501 atcgttctct ccttgtgatt gtattccata gtattatatc aaaaaggtag aataaaatca
    22561 tggaaatgtg gtataataaa gccaagtaaa gagaaaagag aagcacatgt atattgaaat
    22621 ggtagatgaa actggtcaag tttcaaaaga aatgttgcaa caaacccaag aaattttgga
    22681 atttgcagcc caaaaattag gaaaagaaga caaggagatg gcagtcactt ttgtgaccaa
    22741 tgagcgtagt catgaactta atctggagta ccgtaacacc gaccgtccga cagatgtcat
    22801 cagccttgag tataaaccag aattggaaat tgcctttgac gaagaggatt tgcttgaaaa
    22861 ttcagaattg gcagagatga tgtctgagtt tgatgcctat attggggaat tgttcatctc
    22921 tagcgataag gctcatgagc aggccgaaga atatggtcac agctttgagc gtgagatggg
    22981 cttcttggca gtacacggct ttttacatat taacggctat gatcactaca ctccggaaga
    23041 agaagcggag atgttcggtt tacaagaaga aattttgaca gcctatggac tcacaagaca
    23101 ataaacgaaa atggaaaaat cgtgacttga tatccagttt agaatttgct ttgacaggta
    23161 tttttactgc tatcaaggaa gaacgcaata tgcgaaaaca cgcagtgacg gctctagtgg
    23221 tcatccttgc aggttttggt tttcaggtgt cacgaatcga atggctcttt ctcctattga
    23281 gcattttctt ggtagtagcc tttgagattc tcaactctgc tattgaaaat gtggtggatt
    23341 tggccagtca ctatcacttt tccatgctgg ctaaaaatgc caaggatatg gcggctggcg
    23401 cggtattagt ggtttctctt tttgcagcct taacaggcgc attgattttt ctcccacgaa
    23461 tctgggattt attattttaa acagtaagag gaaattatga cttttaaatc aggctttgta
    23521 gccattttag gacgtcccaa tgttgggaag tcaacttttt taaatcacgt tatggggcaa
    23581 aagattgcca tcatgagtga caaggcgcag acaacgcgca ataaaatcat gggaatttac
    23641 acgactgata aggagcaaat tgtctttatc gacacaccag ggattcacaa acctaaaaca
    23701 gctctcggag atttcatggt tgagtctgcc tacagtaccc ttcgcgaagt ggacactgtt
    23761 cttttcatgg tgcctgctga tgaagcgcgt ggtaaggggg acgatatgat tatcgagcgt
    23821 ctcaaggctg ccaagattcc tgtgattttg gtggtgaata aaatcgataa ggttcatcca
    23881 gaccagctct tgtctcagat tgatgacttc cgtaatcaaa tggactttaa ggaaattgtt
    23941 ccaatctcag cccttcaggg aaataacgtg tctcgtctag tggatatttt gagtgaaaat
    24001 ctggatgaag gtttccaata tttcccgtct gatcaaatca cagaccatcc agaacgtttc
    24061 ttggtttcag aaatgcttcg cgagaaagtc ttgcacctaa ctcgtgaaga gattccgcat
    24121 tctgtagcag tagttgttga ctctatgaaa cgagacgaag agacagacaa ggttcacatc
    24181 cgtgcaacca tcatggtcga gcgcgatagc caaaaaggga ttatcatcgg taaaggtggc
    24241 gctatgctta agaaaatcgg tagcatggcc cgtcgtgata tcgaactcat gctaggagac
    24301 aaggtcttcc tagaaacctg ggtcaaggtc aagaaaaact ggcgcgataa aaagctagat
    24361 ttggctgact ttggctataa tgaaagagaa tactaagtag aggtaggctc atgcctgctt
    24421 cttgttttta cagaaggagg acttatgcct gaattacctg aggttgaaac cgtttgtcgt
    24481 ggcttagaaa aattgattat aggaaagaag atttcgagta tagaaattcg ctaccccaag
    24541 atgattaaga cggatttgga agagtttcaa agggaattgc ctagtcagat tatcgagtca
    24601 atgggacgtc gtggaaaata tttgcttttt tatctgacag acaaggtctt gatttcccat
    24661 ttgcggatgg agggcaagta tttttactat ccagaccaag gacctgaacg caagcatgcc
    24721 catgttttct ttcattttga agatggtggc acgcttgttt atgaggatgt tcgcaagttt
    24781 ggaaccatgg aactcttggt gcctgacctt ttagacgcct actttatttc taaaaaatta
    24841 ggtcctgaac caagcgaaca agactttgat ttacaggtct ttcaatctgc ccttgccaag
    24901 tccaaaaagc ctatcaaatc ccatctccta gaccagacct tggtagctgg acttggcaat
    24961 atctatgtgg atgaggttct ctggcgagct cagattcatc cagctagacc ttcccagact
    25021 ttgacagcag aagaagcgac tgccattcat gaccagacca ttgctgtttt gggccaggct
    25081 gttgaaaaag gtggctccac cattcggact tataccaatg cctttgggga agatggaagc
    25141 atgcaggact ttcatcaggt ctatgataag actggtcaag aatgtgtacg ctgtggtacc
    25201 atcattgaga aaattcaact aggcggacgt ggaacccact tttgtccaaa ctgtcaaagg
    25261 agggactgat gggaaaaatc atcggaatca ctgggggaat tgcctcaggt aagtcaactg
    25321 tgacaaattt tctaagacag caaggctttc aagcagtgga tgccgacgca gtcgtccacc
    25381 aactacagaa acctggtggt cgtctgtttg aggctctagt acagcacttt gggcaagaaa
    25441 tcattcttga aaacggagaa ctcaatcgcc ctctcctagc tagtctcatc ttttcaaatc
    25501 ctgaagagca aaaatggtct aatcaaattc aaggggagat tatccgtgag gaactggcta
    25561 ctttgagaga acagttggct cagacagaag agattttctt catggatatt cccctacttt
    25621 ttgagcagga ctacagcgat tggtttgctg agacttggtt ggtctatgtg gaccgagatg
    25681 cccaagtaga acgcttaatg aaaagggacc agttgtccaa agatgaagct gagtctcgtc
    25741 tggcagccca gtggccttta gaaaaaaaga aagatttggc cagccaggtt cttgataata
    25801 atggcaatca gaaccagctt cttaatcaag tgcatatcct tcttgaggga ggtaggcaag
    25861 atgacagaga ttaactggaa ggataatctg cgtattgcct ggtttggtaa ttttctgaca
    25921 ggagccagta tttctttggt tgtacctttt atgcccatct tcgtggaaaa tctaggtgta
    25981 gggagtcagc aagtcgcttt ttatgcaggc ttagcaattt ctgtctctgc tatttccgcg
    26041 gcgctctttt ctcctatttg gggtattctt gctgacaaat acggccgaaa acccatgatg
    26101 attcgggcag gtcttgctat gactatcact atgggaggct tggcctttgt cccaaatatc
    26161 tattggttaa tctttcttcg tttactaaac ggtgtatttg caggttttgt tcctaatgca
    26221 acggcactga tagccagtca ggttccaaag gagaaatcag gctctgcctt aggtactttg
    26281 tctacaggcg tagttgcagg tactctaact ggtcccttta ttggtggctt tatcgcagaa
    26341 ttatttggca ttcgtacagt tttcttactg gttggtagtt ttctattttt agctgctatt
    26401 ttgactattt gctttatcaa ggaagatttt caaccagtag ccaaggaaaa ggctattcca
    26461 acaaaggaat tatttacctc ggttaaatat ccctatcttt tgctcaatct ctttttaacc
    26521 agttttgtca tccaattttc agctcaatcg atcggcccta ttttggctct ttatgtacgc
    26581 gacttagggc agacagagaa tcttcttttt gtctctggtt tgattgtgtc cagtatgggc
    26641 ttttccagta tgatgagtgc aggagtcatg ggcaagctag gtgacaaggt gggcaatcat
    26701 cgtctcttgg ttgtcgccca gttttattca gtcatcatct atctcctctg tgccaatgcc
    26761 tctagccccc ttcaactagg actctatcgt ttcctctttg gcttgggaac cggtgccttg
    26821 attcccgggg ttaatgccct actcagcaaa atgactccca aagccggcat ttcgagggtc
    26881 tttgccttca atcaggtatt cttttatctg ggaggtgttg ttggtcccat ggcaggttct
    26941 gcagtagcag gtcaatttgg ctaccatgct gtcttttatg cgacaagcct ttgtgttgcc
    27001 tttagttgtc tctttaacct gattcaattt cgaacattat taaaagtaaa ggaaatctag
    27061 tgcgagtaaa aattaatctc aaatgctcct cttgtgacag tatcaattac ctaaccagta
    27121 aaaattcaaa aacccatcca gacaagattg aggttttaaa gtattgtccc aaggaaagaa
    27181 aagtaaccct acatcttgaa tctaagtaga ttttatggta aaataatagg gattttaagg
    27241 agtttgatat gtataaccta ttattaacca ttttattagt attatctgtt gtgattgtga
    27301 ttgcaatttt catgcaacca accaaaaacc aatccagcaa tgtatttgat gccagttcag
    27361 gtgatttgtt tgaacgcagt aaagctcgcg gttttgaagc tgtaatgcag cgtttgacag
    27421 ggattttagt ctttttctgg ctagccattg ccttagcatt gacggtatta tcaagtagat
    27481 aagaaaataa tgggcaggac taggtctttg cctcttttta tttttaaagg atgtttgaga
    27541 aggttttaca gtaaaagaaa attaaaaaat ctagaaagaa aatatgaaag atagaataaa
    27601 agaatattta caagacaagg gaaaggtgac tgttaatgat ttggctcagg ctttgggaaa
    27661 agacagttcc aaggattttc gtgagttgat taaaaccttg tccttaatgg aaagaaagca
    27721 ccagattcgc tttgaagaag atggcagtct gaccttggaa gccaagaaaa aacatgagat
    27781 taccctcaag gggatttttc atgcccataa aaatggtttt ggttttgtca gcctagaagg
    27841 ggaagaggac gacctttttg tagggaaaaa tgatgtcaac tatgctattg atggtgatac
    27901 cgtcgaggta gtgattaaga aagtcgctga ccgcaataag ggaacagcag cagaagccaa
    27961 aattattgat atcctagaac acagtttgac aacagttgtc gggcaaatcg ttctggatca
    28021 ggaaaagcct aagtatgctg gctatattcg ttcaaaaaat cagaaaatca gtcaaccgat
    28081 ttatgttaag aaaccagccc taaagttaga aggaacagaa gttctcaagg tctttatcga
    28141 taaataccca agcaagaaac atgatttctt tgtcgcgagt gttctcgatg tagtgggaca
    28201 ctcaacggat gtcggaattg atgttcttga ggtcttggaa tcaatggaca ttgtatccga
    28261 gtttccagaa gctgttgtta aggaagcaga aagtgtgcct gatgctccgt ctcaaaagga
    28321 tatggaaggt cgtctggatc taagagatga aattaccttt accattgacg gtgcggatgc
    28381 caaggacttg gacgatgcag tgcatatcaa ggctctgaaa aatggcaatc tggagcttgg
    28441 agttcacatc gcagatgttt cttattatgt gaccgagggg tctgcccttg acaaggaagc
    28501 ccttaaccgt gcgacttctg tttacgtgac agaccgagtg gtgccaatgc ttccagaacg
    28561 actatcaaat ggcatctgct ctctcaatcc ccaagttgac cgcctgaccc agtctgctat
    28621 tatggagatt gataaacatg gtcgtgtggt caactatacc attatacaaa cagttatcaa
    28681 gaccagtttt cgtatgacct atagcgatgt caatgatatc ctagctggcg atgaagaaaa
    28741 gagaaaagaa tatcataaaa ttgtaccaag tatcgaactc atggccaagc ttcatgaaac
    28801 tttagaaaac atgcgtgtga aacgtggagc cctcaatttt gataccaatg aagcgaagat
    28861 tttagtggat aaacaaggta agcctgttga tatcgttctt cggcagcgtg gtattgccga
    28921 gcggatgatt gagtctttta tgttgatggc taatgaaaca gttgccgaac atttcagcaa
    28981 gttggatttg ccttttatct atcgaattca cgaggagcct aaggctgaaa aggttcagaa
    29041 gtttattgat tatgcttcga gttttggctt gcgcatttat ggaactgcca gtgagattag
    29101 tcaggaggca cttcaagaca tcatgcgtgc tgttgaggga gaaccttatg cagatgtatt
    29161 gtccatgatg cttcttcgct ctatgcagca ggctcgttat tcggagcaca atcacggcca
    29221 ctatggacta gctgctgact attatactca ctttaccagt ccaattcgtc gttatccaga
    29281 ccttcttgtt caccgtatga ttcgggatta cggccgttct aaggaaatag cagagcattt
    29341 tgaacaagtg attccagaga ttgcgaccca gtcttccaac cgtgaacgtc gtgccataga
    29401 agctgagcgt gaagtcgaag ccatgaaaaa ggctgagtat atggaagaat acgtgggtga
    29461 agagtatgat gcagttgtat caagtattgt caaattcggt ctctttgtcg aattgccaaa
    29521 cacagttgaa ggcttgattc acatcactaa tctacctgaa ttttatcatt tcaatgagcg
    29581 tgatttgact cttcgtggag aaaaatcagg tatcactttc cgagtgggtc agcagatccg
    29641 tatccgtgtt gaaagagcgg ataaaatgac tggagagatt gatttttcat tcgtacctag
    29701 tgagtttgat gtgattgaaa aaggcttgaa acagtctagt catagtggca gagggcgtgg
    29761 ttcaaatcgt cgttcggata agaaggaaga caagagaaaa tcaggacgct caaatgataa
    29821 gcgtaagcat tcacaaaaag acaagaagaa aaaaggaaag aaaccttttt acaaggaagt
    29881 agctaagaaa ggagccaagc atggcaaagg gcgagggaaa ggtcgtcgca caaaataaaa
    29941 aggcacgcca cgactataca atcgtagata cgctagaggc agggatggtc ctgactggaa
    30001 ctgaaatcaa gagtgtacga gctgctcgaa ttaatctcaa ggatggcttt gctcaagtga
    30061 aaaatggaga agtttggctg agcaatgttc atatcgcgcc ttacgaagag ggcaatatct
    30121 ggaaccagga accagaacgt cgtcgtaaac tcctgctcca taaaaggcaa attcaaaaat
    30181 tggaacaaga gaccaaaggg acaggaatga ccttagttcc ccttaaggtc tatataaaag
    30241 atggctacgc taagcttctt ttaggacttg ccaaagggaa gcatgactat gacaaacggg
    30301 agtctatcaa acgtcgtgag caaaatcgag atatcgcgcg tgtgatgaaa gctgttaatc
    30361 agcgataaaa agaggaattg aaaatggaaa aattagttgc ctataaacgc atgcctttgt
    30421 ggaataaaca aacaatgcct gaagctgttc agcaaaagca caatacaaaa gttgggactt
    30481 gggggaaaat tactgtcttg aagggagctc tcaagtttat tgaattgaca gaagaagggg
    30541 aagttctagc tgaacacctc tttgaagcag gggcagacaa tccaatggcc caacctcaag
    30601 cctggcaccg agtggaagct gccacagatg atgtggaatg gtacttggaa ttttattgta
    30661 aacctgagga ttattttgct aaaaaataca ataccaatcc tgttcattca gaggtcctag
    30721 aggccatgga gacagtgaaa caagggaaag ctttggattt gggttgtggt caggggcgta
    30781 attctctttt tctagcccag caagattttg atgtgacggc tgtagatcaa aatggactag
    30841 ctcttgaaat cttgcaaagc attgtggagc aggaagattt ggacatgcct gttggccttt
    30901 acgatatcaa ttcagctagc attgaacaag aatatgattt tatcgtttca acagttgttc
    30961 tcatgtttct acaagcggac cgcattccag ctattattca aaatatgcag gagaaaacca
    31021 gtgttggtgg ttacaacctt atcgtttgtg ccatggacac ggaggattat ccttgctcgg
    31081 ttaacttccc attcaccttt aaagaaggag aactggcaga ctattacaag gattgggaat
    31141 tggttaagta caatgaaaat ccaggccatt tgcatcgtcg cgatgagaat ggcaatcgta
    31201 ttcaactacg ctttgcgacc ttactagcta agaaaatcaa gtaaacacac atgaagatta
    31261 ggaattttcc tgatcttttt tcttttttac gaatgatata gaaaaggagg gaattcatgt
    31321 ttgttgcgag agatgctagg ggagaattgg taaatgtgtt agaggataaa cttgagaagc
    31381 aagcatacac ctgcccagct tgtggaggcc agctccattt gcgtcaagga ccaagtgtac
    31441 ggacgcattt tgcccataaa tccttaaaag actgtgattt tttctttgaa aatgaaagtc
    31501 cagaacacct ggccaataag gaatccctct atcactggtt gaaaaaagag acaaaggttc
    31561 aattagagta cccgctttca gaacttaaac agattgcgga tgtatttgta aatggcaatc
    31621 tagctctaga agttcagtgt agtcccttgc ctcagaaagt ccttaaagag cgaagtgagg
    31681 gctatcgtag tcagggttac caagtactgt ggttgctggg tcaaaaactg tggctcaagg
    31741 agcgtttgac tcgtctacag caaggttttc tttatttcag tcaaaacatg ggcttttatg
    31801 tttgggaatt agacaaggaa aaacaagttt taagactcaa atacctgatt taccaggatc
    31861 tccgcggtaa actccattat caaatcaagg aattttccta tggtcaaggt agtttattgg
    31921 aaatattgcg tcttccctat aagagacaaa aaatatctca ttttacagtt tctgaggaca
    31981 aggacatctg tcgctatatc cagcaacaac tttattatca aaatctcttt tggatgaaag
    32041 aacaagcaga agcctatcaa aagggagaaa atatcctgac ttatggactg aaagaatggt
    32101 atccacaaat tcgaccaata gtgggcaaat ttttccagat tgaacaagac ttgactagct
    32161 attatcagca cttttatacc tattaccaaa aaaatcctca aaatgattgg caaaagcttt
    32221 atccaccagc cttttatcag caatatttct tgaaaaatat ggtagaatag aaaggatgga
    32281 ggaatctaat ggtattacaa agaaatgaaa taaatgaaaa agatacatgg gatctatcaa
    32341 cgatctaccc aactgaccag gcttgggaag aagccttaaa agatttaaca gaacaattgg
    32401 agacagtagc ccagtatgaa ggccatctct tggatagtgc ggataaccta ctagaaatca
    32461 ctgaattttc tcttgaaatg gaacgccaga tggagaagct ttacgtttat gctcatatga
    32521 agaatgacca ggatacacgt gaagctaagt atcaagagta ctatgccaag gccatgacac
    32581 tctacagcca gttagaccaa gccttttcat tctatgatcc tgaatttatg gagattagcg
    32641 aaaagcagta tgctgacttt ttagaagctc aaccaaagct gcaggtttat caacactatt
    32701 ttgacaagct cttgcaaggc aaggatcacg ttctttcaca acgtgaagaa gaattattgg
    32761 ctggagctgg agaaatcttt ggttcagcaa gtgaaacctt cgctatcttg gacaatgcgg
    32821 atattgtgtt cccttatgtc ctagacgatg atggtaaaga agttcagcta tctcatggga
    32881 cttacacacg tttgatggag tctaaaaaac gtgaggttcg ccgtggtgcc tatcaagctc
    32941 tttatgcgac ttacgaacaa ttccaacaca cctatgccaa aaccttgcaa accaatgtta
    33001 aggtgcaaaa ttaccgtgct aaagttcgta actacaagag tgctcgtcat gcagccctcg
    33061 cagcgaattt tgttccagaa agtgtttatg acaatttggt agcagcagtt cgcaagcatt
    33121 tgccactctt acatcgctat cttgagcttc gttcaaaaat cttggggatt tcagatctca
    33181 agatgtacga tgtctacaca ccgctttcat ctgttgaata caattttacc taccaagaag
    33241 ccttgaaaaa agcagaagat gctttggcag tcttgggtga ggattacttg agccgtgtca
    33301 aacgtgcctt cagcgagcgt tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg
    33361 cctactctgg tggttcttac gataccaatg cctttatgct tctcaactgg caggacaatc
    33421 tggacaatct ctttactctt gttcatgaaa caggtcacag tatgcattca agctatactc
    33481 gtgaaactca gccttatgtt tacggagatt actctatctt tttggctgag attgcctcaa
    33541 ctaccaatga aaatatcttg acggagaaat tattggaaga agtggaagac gacgcaacac
    33601 gctttgctat tctcaataac ttcctagatg gtttccgtgg aacagttttc cgccaaactc
    33661 aatttgctga gtttgaacac gccattcacc aagcagatca aaatggggag gtcttgacaa
    33721 gcgatttcct aaataaactc tacgcagact tgaaccaaga gtattatggt ttgagtaagg
    33781 aagacaatcc tgaaatccaa tacgagtggg ctcgcattcc acacttctac tataactact
    33841 atgtatatca atattcaact ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc
    33901 atggtagtca agaagaccgt gaccgctata tcgactacct caaggcaggt aagtcggact
    33961 atccacttaa tgtcatgaga aaagctggtg ttgatatgga gaaggaagac tacctcaacg
    34021 atgcctttgc agtctttgaa cgccgtttaa atgagtttga agcccttgtt gaaaaattag
    34081 gattggcata aaatggttga atcgtatagt aagaatgcta accataacat gcgtcgtcct
    34141 gtcgtcaaag aagaaattgt agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc
    34201 ttgaaagaat tggaagaatt tgcccgcaag gaaaatattc ctattattcc ccatgaaacg
    34261 gttgcttatt tccgttttct tatggaaacc atgcagccta aaaatattct ggaaattggg
    34321 acggctatcg gtttttcagc tctcttgatg gctgaacatg cgccaaatgc taagattaca
    34381 actattgatc gtaatccaga aatgattggt tttgccaagg aaaattttgc ccagtttgac
    34441 agtcgcaagc aaatcactct cctagaggga gatgcggtgg atgtcttatc tacactgaca
    34501 gagtcttatg atttcgtctt tatggattct gccaagtcta aatacatcgt ctttctgcca
    34561 gaaatcctca aacatttgga agttggtggt gtggttgtct tggatgatat ttttcaaggt
    34621 ggtgatgttg ccaaggatat tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc
    34681 cttcaaaaat tatttgatgc aaccttagac aatccagaac tcaccgcaac attagtgcct
    34741 ttaggagatg gtattctcat gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc
    34801 gaatgatttt cagaaaaatt taagaaaaaa tagtaaaata gatagagtaa cacttatctc
    34861 aaaggagtag acatgaagaa aaaattattg gcaggtgcca tcacactatt atcagtagca
    34921 actttagcag cttgttcgaa agggtcagaa ggagcagacc ttatcagcat gaaaggggat
    34981 gtcatcacag aacatcaatt ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc
    35041 ttgttaaata tgaccatcca aaaagttttt gaaaaacaat atggctcaga gcttgatgat
    35101 aaagaggttg atgatactat tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt
    35161 gtcttgtcac aagcaggtat gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa
    35221 ttagttgagt tggcagttaa gaaggtagca gaagctgaat tgacagatga agcctataag
    35281 aaagcctttg atgagtacac tccagatgta acggctcaaa tcatccgtct taataatgaa
    35341 gataaggcca aagaagttct cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta
    35401 gccaaagata attcaactga tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat
    35461 tctgcttcaa cagaagtacc tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat
    35521 ggtgtttctg atgtgattac agcaactggc acacaagcct acagtagcca atattacatt
    35581 gtaaaactca ctaagaaaac agaaaaatca tctaatattg atgactacaa agaaaaatta
    35641 aaaactgtta tcttgactca aaaacaaaat gattcaacat ttgttcaaag cattatcgga
    35701 aaagaattgc aagcagccaa tatcaaggtt aaggaccaag ccttccaaaa tatctttacc
    35761 caatatatcg gtggtggaga ttcaagctca agcagtagta catcaaacga atagtccaaa
    35821 tcaatgagtc agggaaaaaa actcgacttc aggaaaaaat gaagcaaaca ttcccaaaat
    35881 aaaacgcata gtacaaggtt tgtactgccc ccaaaagtta gacaattaat ttatctgaag
    35941 gatttagttc tgtattgcac agggctaagt ccttttagtt ttaccttaat tctcttattg
    36001 ttgtaataat caat
//
LOCUS       DAVHKZ010000020        34465 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000020 DAVHKZ010000000
VERSION     DAVHKZ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34465
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.020"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(202..492)
                     /locus_tag="VVO74_001177"
     CDS             complement(202..492)
                     /locus_tag="VVO74_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695200.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(480..731)
                     /locus_tag="VVO74_001178"
     CDS             complement(480..731)
                     /locus_tag="VVO74_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU5695201.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            935..1138
                     /locus_tag="VVO74_001179"
     CDS             935..1138
                     /locus_tag="VVO74_001179"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695202.1"
                     /translation="MKIKEQTRKLATGCSKHCFEVVDKTDEVSSKHCFEVVDRTDEVS
                     SKHCFEVADRTDEVSNIYTARRR"
     gene            complement(1175..2059)
                     /locus_tag="VVO74_001180"
     CDS             complement(1175..2059)
                     /locus_tag="VVO74_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU5695203.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(2204..3355)
                     /locus_tag="VVO74_001181"
     CDS             complement(2204..3355)
                     /locus_tag="VVO74_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEU5695204.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(3501..5267)
                     /locus_tag="VVO74_001182"
     CDS             complement(3501..5267)
                     /locus_tag="VVO74_001182"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEU5695205.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRS
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYCACQLLGPLHK"
     gene            complement(5350..8466)
                     /locus_tag="VVO74_001183"
     CDS             complement(5350..8466)
                     /locus_tag="VVO74_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU5695206.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKEDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNDYEVFTQHIDSLESNNLSIDLKGLKGKKVRISLRSAGIPLSLA
                     EVEVYTYK"
     gene            complement(8476..10770)
                     /locus_tag="VVO74_001184"
     CDS             complement(8476..10770)
                     /locus_tag="VVO74_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU5695207.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(10829..11629)
                     /locus_tag="VVO74_001185"
     CDS             complement(10829..11629)
                     /locus_tag="VVO74_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU5695208.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(11626..12399)
                     /locus_tag="VVO74_001186"
     CDS             complement(11626..12399)
                     /locus_tag="VVO74_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU5695209.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(12424..12894)
                     /locus_tag="VVO74_001187"
     CDS             complement(12424..12894)
                     /locus_tag="VVO74_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU5695210.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(12885..13316)
                     /locus_tag="VVO74_001188"
     CDS             complement(12885..13316)
                     /locus_tag="VVO74_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU5695211.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(13309..13749)
                     /locus_tag="VVO74_001189"
     CDS             complement(13309..13749)
                     /locus_tag="VVO74_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEU5695212.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(13761..14399)
                     /locus_tag="VVO74_001190"
     CDS             complement(13761..14399)
                     /locus_tag="VVO74_001190"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEU5695213.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            complement(14514..15917)
                     /locus_tag="VVO74_001191"
     CDS             complement(14514..15917)
                     /locus_tag="VVO74_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEU5695214.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            16093..16866
                     /locus_tag="VVO74_001192"
     CDS             16093..16866
                     /locus_tag="VVO74_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU5695215.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(17994..19499)
                     /gene="adcA"
                     /locus_tag="VVO74_001193"
     CDS             complement(17994..19499)
                     /gene="adcA"
                     /locus_tag="VVO74_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU5695216.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVTKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYVEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(19509..20315)
                     /locus_tag="VVO74_001194"
     CDS             complement(19509..20315)
                     /locus_tag="VVO74_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU5695217.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(20308..21012)
                     /locus_tag="VVO74_001195"
     CDS             complement(20308..21012)
                     /locus_tag="VVO74_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU5695218.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVSHA"
     gene            complement(21012..21452)
                     /gene="adcR"
                     /locus_tag="VVO74_001196"
     CDS             complement(21012..21452)
                     /gene="adcR"
                     /locus_tag="VVO74_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU5695219.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(21607..22875)
                     /gene="dltD"
                     /locus_tag="VVO74_001197"
     CDS             complement(21607..22875)
                     /gene="dltD"
                     /locus_tag="VVO74_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU5695220.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(22868..23107)
                     /gene="dltC"
                     /locus_tag="VVO74_001198"
     CDS             complement(22868..23107)
                     /gene="dltC"
                     /locus_tag="VVO74_001198"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU5695221.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(23121..24365)
                     /gene="dltB"
                     /locus_tag="VVO74_001199"
     CDS             complement(23121..24365)
                     /gene="dltB"
                     /locus_tag="VVO74_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU5695222.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(24362..25912)
                     /gene="dltA"
                     /locus_tag="VVO74_001200"
     CDS             complement(24362..25912)
                     /gene="dltA"
                     /locus_tag="VVO74_001200"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU5695223.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKSDSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     ITDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDSVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(25933..26064)
                     /locus_tag="VVO74_001201"
     CDS             complement(25933..26064)
                     /locus_tag="VVO74_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU5695224.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(26295..26999)
                     /locus_tag="VVO74_001202"
     CDS             complement(26295..26999)
                     /locus_tag="VVO74_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU5695225.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPISNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(27069..28895)
                     /gene="glpO"
                     /locus_tag="VVO74_001203"
     CDS             complement(27069..28895)
                     /gene="glpO"
                     /locus_tag="VVO74_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU5695226.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKSDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTSAANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            complement(28937..30445)
                     /gene="glpK"
                     /locus_tag="VVO74_001204"
     CDS             complement(28937..30445)
                     /gene="glpK"
                     /locus_tag="VVO74_001204"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU5695227.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(30604..32031)
                     /locus_tag="VVO74_001205"
     CDS             complement(30604..32031)
                     /locus_tag="VVO74_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU5695228.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSENENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPTFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            32196..33068
                     /gene="hslO"
                     /locus_tag="VVO74_001206"
     CDS             32196..33068
                     /gene="hslO"
                     /locus_tag="VVO74_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU5695229.1"
                     /translation="MNKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            33055..34035
                     /gene="dusB"
                     /locus_tag="VVO74_001207"
     CDS             33055..34035
                     /gene="dusB"
                     /locus_tag="VVO74_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEU5695230.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(34265..>34465)
                     /locus_tag="VVO74_001208"
     CDS             complement(34265..>34465)
                     /locus_tag="VVO74_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HEU5695231.1"
                     /translation="NANGSMATGWLKDGDTWYYLEASGAMKESQWFKVSDKWYYVNGS
                     GALAVNTTVGGYRVNANGKWVN"
BASE COUNT        10335 a         7582 c         5953 g        10595 t
ORIGIN      
        1 atctgaatct ttgagatgag ctttataaat cgcttttttc agtttttgca ctggtgtttc
       61 gataaactca aactttttag ccgtggtatt gcctgatttt atagtatatt gaaactagaa
      121 tagtacacct ctacttctaa aacattttta gaaatcgatt tgactgtcct gatcgattta
      181 tcctgttctt atttcatttt actatatttg agccacttcg tctttaacgg ctttattcat
      241 aagctcttgt aatttttctt tactatcaat tacttctgat tttccgttgt aatttattgt
      301 aataggtttt aacttaccta atttctcgac acgctcatta atttgatctt ttttgaaggc
      361 tgcatatgtt tttcctaaga ttttttcgaa aatatattta tcagatagcg gtttgccttc
      421 ttcttcagct tggtttttgt attgatttga aacataagga acaaatcctt catagtaacc
      481 taatgctccc ataagttcaa aagcttgttt tctaattcaa accattgcaa ctcagatttc
      541 agcttttcag ataaatcctg ctcatccaaa taatgacttg aaattagtgc tgaactcgtt
      601 tctgtatcct gtacaggctg agcacccata ccagcaaaaa ataaactcgt tcctagcaag
      661 accgaacaag ctcctattgc atatggcctc aaagaaaaac gctgctttct ctcaaattga
      721 aattctttca tcccatctcc catcattcat tattactgta tattttgtat atcagaaata
      781 gtttgtattc acaaatcttt ctagttattc ccttatcatt cctaattaag ggagataaca
      841 tacaataatt tttagttaaa tgtatatcga tgttttttgt ttttcttaat aaacgcaata
      901 caaaaagagc ctgttgccaa gctctttgta ctcaatgaaa atcaaagagc aaactaggaa
      961 actagccaca ggttgctcaa aacactgttt tgaggtagta gataagactg acgaagtcag
     1021 ctcaaaacac tgttttgagg ttgtggatag aactgacgaa gtcagctcaa aacactgttt
     1081 tgaggttgca gatagaactg acgaagtcag taacatctat acggcaaggc gacgctgacg
     1141 tggtttgaag agattttcga agagtattag tctattattt cttctcagcg cgaagggctg
     1201 acaagatttg tgttcggata tcatccacac catttggagt atttggtaaa aagatggttt
     1261 gatttccttt agaggcaaag gtattcaagg tatccaaata ctggttggtc aagaggatag
     1321 acatgatttg ttcttctgtc atgccaacat tggcttcctt gagttcggtg atagactctg
     1381 ccaatccatc cacaatcgcc ttacgttgtt gggcaatccc cacaccatga aggcggtctt
     1441 tttctgcttc tgcttcagct gcagtgacaa ttttaatctt gtcagcttcc gccaattctt
     1501 gtgctgcgac ccgcttacgt tgcgccgcat tgatttcatt catggattgc ttaacttctg
     1561 catctggttc gaccttggta atcaaggttt tcacgataat gtagccgtaa gtggtcattt
     1621 cttctgctac ttggtgttga acctcaaggg caatctcatc ttttttctca aacaattcat
     1681 ccaaggttaa ttttggaaca gaagagcgaa gagcatcttc gatataagat ttaatctgag
     1741 attctggacg tatgagttta tagtaagcat ctgtcacgct ctgctcgttg acacggtact
     1801 gagtcgctac attcatcata acgaacacat tgtccttggt cttagtctca accacaatat
     1861 cactttgcaa caagcgcaac tgaatccgtg ctgcaatcga gtcaatccca aaaggcaagc
     1921 gaatatgaat accgctatta gcaacctttt ggtatttccc aaagcgttca ataatcgcca
     1981 ccgactgctg acgaaccaca taaactgtac tcagtgtgac tatcaccaat aggagcacac
     2041 aaacaatcag aaaaatcatg aaaaatattg ccataatgga acctccacaa gtatttttct
     2101 agtattatag cacatttaaa gaaggctgtg ccgtttttac tgcgattttt cctgaaatgt
     2161 caataattag aggtgaattg tcctattgtc gtccaatctc ttgctaaaat aactctttat
     2221 aaaaggcaat cgtttcttct aaggttggca taaatggatt tcctggtgcg caggcatcaa
     2281 tcaaggcatt cttagaaagg tattcaaagt cgaaatcttt ttcttcaata ccaagttcag
     2341 tcagtttctt aggaatacct actgtctcag aaagcttctc aatctcagca atcgcataat
     2401 cggcacattc ttgatctgat ttaccttcta catgaagtcc caaggctttg gcaacattgc
     2461 ggaaagcttc tggtacacgt ttagcatttt cacgttctat aactggtagc aacatggcac
     2521 agcacacgcc atgtggcaaa ttatatactg caccgagttg gtgagccatt gagtgaacat
     2581 aaccaagacc agcattatta aagctcatac caccaaggaa gatggcattg accatacctt
     2641 cacgcgcttc aatatcatgt ccattttcta cagcacgagg aagatattcc ttgataagct
     2701 caatagcacc aatagacagt ttcttggtta catcataagc accaggtgtt accaaagctt
     2761 caacagcgtg agtcagagca tccataccag tagcagcagt caggccttta ggtttggaaa
     2821 gcatgagttc cgggtcatta acagagataa gagcaaggct attcttgtca accattacca
     2881 tcttaacctt gcgttcttca tcagtaatca catagttaat agtgatttct gcagaagttc
     2941 ctgccgttgt attgatagcc acaactggca agcctttttt agcagactta tgaagccctt
     3001 cataatcctg tggttttcca ccatttgtag ccatgataga aatacaacta gctgcatcct
     3061 gtggagaacc cccgccaaga ctgatgataa agtcacagcc atgttcttgc aaagcagcta
     3121 ccccatctgt gacattttta caagtagggt ttggctctac atcgctaaag atgacatatt
     3181 cgattccttc tgtatccagt ggttttaaag tcttaggtaa aatatcactg ccttcgatgt
     3241 acttatctgt aaccaaaagt gcctttttat agccaagttc cttgatataa ggacccactt
     3301 catttacaac accttttcca ataaggttga ctgccggaac ataaaatgta gccatataat
     3361 tttcctcctg cgcctccgcg ctatctattt aacatcatta tattactttt tgtattcgtt
     3421 tttaattatt tgtgaattgt ttaacaaatc tttttaaaag gataggaggg acgtaagttc
     3481 acctcctata taaacaagtt ttatttatgt agtggtccca acaactgaca tgcacaatag
     3541 tctgctgatt ctagatcttc tgttccaaat aaggaccaat ttttaggtct aaagatatct
     3601 tcctcaggta cattatgcat attgacagga attctcaaca tagaagccaa ggtaatcaag
     3661 tctgctccaa tgtgtccata tgttatggct ccgtgattag ctccccaatt attcatgacg
     3721 tcatagacag acttgaaagc accttttcct gtcaaacgtg gagcaaacca agtagttggc
     3781 catcctggat ctgtacgatt atctaaagta tggtgaacat cttcaggaag ttcaagtgta
     3841 taaccttctg caatttgtag cactggacca acccctttta gaagattgag acgtaccatt
     3901 gttactggca tatccccctt cgtcaagaaa cgagttgaga atcctcctcc acggaagtat
     3961 tcgcggtttg ctggtgggaa gtctgtattt tcaagcatag cctgcacttc actttcttcc
     4021 aactcccaga atggtttcat aacaggtttg ccatctcgag tagcttgacc tgtaccatcc
     4081 aatgtacaag aaccagagtt gattagatgt aagaagccag ctgcagcacg accctctaaa
     4141 gtatgtcccg ttacacgttt aacagcctct gggctccaat aagtacgcac atcagcaaag
     4201 atttgtggag tatttgttaa tagataatta aagagcatag acacaccatt tagtgaatca
     4261 ttctctgtcg caaatacaaa tggttttcga ataccattcc agtcaaactg agtattgagg
     4321 aaagtttcca taaaatctcc atttggaaaa tggtctgtcc actgacgttg accttggaaa
     4381 ccagctacta aagcatgatg accaactgct tcttcctcaa aaccaagttc agcaagtctt
     4441 gggttaccaa ccattaagtc acgtccaatc atgaacatct taataacaaa ttcccattgt
     4501 ctatcttttt cttcacggct taaaacaagg tcttcacggt tatggtcgaa tccttctttt
     4561 acgttttctt tcacccattt gagcgcacgt tcgaactctt cagggtcgta aatactacgg
     4621 tccatacggc gcgtgaactc cgtcatatct accgattcat ttcgcattcc taggtattct
     4681 tggaagaaat ccggatttac aatagaacca ccaatcccca tcgaaacact acccattgat
     4741 aggtaagcag tgtctctcat caagccagtt gcaagagctg cacgcgcata gcgtaaaagt
     4801 ttttctttga catcttctgg aatatctgtg tcactagctt cctgaacatc tcttccataa
     4861 atcccaaagg ctggaatccc tttttgagca tgtgaagcta gtacagctgc aagatagaca
     4921 gctcctgggc gttctgtccc attaaatccc caaatagcat gaggaatatc tggagacata
     4981 tccatagttt cactaccata acaccagcat ggtgtaactg taattgttgc gcaaacattt
     5041 gattttttaa acaactcatg ggaagctgca gcctctggta cacggccaat agtagatgga
     5101 gaaatcacgc attccacagg ttccccatct ggatatttca atgtgcttga aatcaaatct
     5161 gccacacttt tagccatgtt cattgtttgc acttcaagtg attcgcgtac accttgacga
     5221 cgaccatcaa tagtcggacg aatcccaata cgtggatgtt gaatcatact attttcctct
     5281 tatttttctg tttctttcat actaccatct ccattatatt tacggtagcc tgggtgataa
     5341 tttttaaaat tacttataag tataaacctc tacctctgct aaacttaaag gaattcctgc
     5401 gcttctcaaa gaaattctaa ccttttttcc cttcagtcct tttaagtcta tggatagatt
     5461 attgctttct aaactgtcaa tatgttgtgt aaaaacttca taatcatttg aatcatatat
     5521 aataatatca aaatttgata atctctgaat ttcagcatct gttctattat aaataattaa
     5581 cttttctaat tcttcggttt gtgctaaatc tatctcccac catgaaggag aatcttcttt
     5641 ggtatgagtc actgaatgat gaccataatc tccgttttta tttccatcaa ctgctagacg
     5701 agaaaaacca ttgtaatccg ttgaactctg tcgagtttct tttgttaatg caatattaga
     5761 aagtttcttc ggagttctct ttgaaccata gacttcaact tccgctaaac ttaacggaat
     5821 agctgctgat tttaattcta ttttgactag cttagcccct acagaaggta cttttaaaga
     5881 taacaaacca tcaactactt tatcaaaatg tcttctaaaa acttcttctc ctgatgaaga
     5941 tagaaaaata acatcaaaat tagataaacg ctgaggttcg gcatctgttc tattataaat
     6001 atcaacttta gaaaccgtaa actcttctcc cagatcgacc tgccaccaag cgttagaatc
     6061 tgccttagta tgagtcaccg aatgatgtcc gtaatctcca tctttattac catcaactgc
     6121 taaagcagct acaccctcat aattggttga actttgagta gctaccttat ttgtagagac
     6181 tactttatct tctgttattt tatctatatc ctcttcagat tgcttaccat ctgattctct
     6241 aaaaacctct acttctgcta aactcaaagg cactccactc gttagtaatt taactttaat
     6301 ataccttgct cctttttctt tgaaatctag actaacagat tcacccgaca aattattaac
     6361 atgtttctta gcaacttcgt ttctattatt gtcatataga atcacatcaa aattagatag
     6421 acgttgagtc tcagcatctg tgcgattata aattttaaca agcccaactt tatccatttt
     6481 tttcaaatcg acttcccacc aagagggatt atctgcccta gtgtgtgtta ccgaaccaga
     6541 gttaaaatta ccatttctgt taccatccac agctctatta gggtctccat tgtaatctac
     6601 agaactttgt gttgttggtt ttgcatatgc tatattcaaa ttaccatcat taaatttatc
     6661 tggtgttggg aaagagactg gacctgtccc ctcagtattt atagacatct ctaccattcc
     6721 attatgatta accgtaatgg tataaacatg ggtattctca tcccaatttt ctgtataagt
     6781 ataatgattt ttatcgccac ttatatttat ctgaggttta tgaccagtat gcccttttaa
     6841 tgtaagtgtt gttgtcctaa agtcattatc tacaggattg atggaataat ttttgcttat
     6901 ccagttcgct aactctaatt cttctttctt ccaacttttt gatgcatcaa aatttcctga
     6961 taatgcccac atagctgtct tatctgtcct gtaattattc aataaaatat gtaaattatt
     7021 tggattttct ttaacaacag cgtaagtatg tggcgtcaaa tctaacgata acgactttgt
     7081 attattagta tacataggca acattacttg ctgattttta ttgatattag cattactatt
     7141 ataaatatac caggaattac ctacacgctg agcataccca tctccttcat aaagttttgg
     7201 ataaagcgag tttaaatagt tgactttact agacaattcc tcactatttt tagtcaaaat
     7261 ttttgcatta gggaatatag atgaaatctt ttccttatca attttctcat gtattacagg
     7321 aagaatatga tatctcccat tattatataa aggcattgtt tcatcattcg aataaagtcc
     7381 ttgataaaat ccgtttaatg aactaatcct accttctcca ttccaaaata cagcttttgt
     7441 tctatttaca acttcttcct tacttggagc tggattttgt atagcatgtc taaagaaagg
     7501 aataatacct ttagtaaatg ctggagttgg tacatcattt gtcataaatg tatacgcggc
     7561 acattcgaaa ttataaactg tgcctccccc agtatataca ttcatcattt ccatagcaat
     7621 cattgattct ggttccgatg cataggatct catatcccta gctcttccag tttcaaatgt
     7681 gtttgtataa tgtttttccc accatttcca tgtatctgtt gatgagcccc agttatcaca
     7741 taagccactc aaccaaaatc cactaacgat agaatctgta cccgcatcat ctcttattgg
     7801 cgtattttta gttgccaaca ccaaattttt atgatatttt tgactcgctt caaagaatgt
     7861 cggatcattc ataatagttt cccagaacca tttttcatga tcatgccaga taaaatgcgc
     7921 tccatatttg gcacaaactt ccaaatattt agcactatgc ggagctaact ggttattgta
     7981 aatccaataa ttctcaatat ttaaaacacc ttttaacaca ctatactttt ggaattgttc
     8041 atctaaccac tctggaggaa ctgtattacg ctctccagcc gacataataa ccaagaaaac
     8101 tggaatgttt agactttgag cttcctccaa catcttgaca taccattctc tcaattcttt
     8161 cgtatctcgt ggaatacaac ttgttggttt acagactttt gcaggatgaa gttcaatcgc
     8221 tgcatatggc tttacatctt caggaatagc ttcccatgct cccttcaatg tgttccccca
     8281 ccataatccg ttaccattat cattgccata caacggagaa agcaacaatg gcgattcatt
     8341 attaatcgtc gttctcattt gaacacgatt atcagcctta actcctgcta acaatccaaa
     8401 acataacatc ccaatacata caaacaatat tgtgattaat tttcttttta ttttttcttt
     8461 attcatgact tatacctaaa aatttaactc aataattttt tctgaattaa ataccaattc
     8521 aatattttgt acatcagtat ttttgccata tattcttact cttacttttt gatctttgtt
     8581 tcctccttcc aattttagga atgttatatc cccatttttc caagcaaacg ataccttata
     8641 tcctcctctt actctgaaac ctttcacttc tccttctgac caagcagaag gtaaagctgg
     8701 aattagtgat aaccaattat gatggctctg tactaataat tcacaaattc cactcaccaa
     8761 acctaaatta ccatcaattt gaaatggtgg atggtcaaga aataaattgc caagagtcgc
     8821 attatttaac aaaccattaa tctggttata agcaggttca ccttgatata gtctcgcaaa
     8881 aaaatgaatc agccatgcag cactccaacc tgtttgtgta ctagcatgca aaccacttac
     8941 taaccaatta ttaatcgctt gctccctctc ctgtgaagat aaaaaattag cgtttgataa
     9001 tctcctattg atagtgattt tagctgcttc tgctaattcc ggagttttat gaatatcaat
     9061 ctcattataa ggataaagcc caaatagagg tgaaatgtgt ctatgcccag gctctacttc
     9121 ttcataatct tctaaccatt cttggatttg cccattacta cctatttttg ttttaggtag
     9181 tttctttttt aactccttca cacgactaat aaaatccgaa ttgtctccta attgttttgc
     9241 aatgccaatg catgaatcac aaaaatatct tagaatttga ttatcaattg tagatgatag
     9301 acaagcattt ccttcaatac cattttttaa gcgatattta ttttccggtg agacacttgg
     9361 acctgtcatc aagtagccat ccacctcaaa taaataatct tcaaagaaaa gaaatgcttc
     9421 ttttatcatt tcaaaatgtt ccgtaagaat acgctcatct tggaaatata aatagtgttc
     9481 ccaaatatga gtacataacc atggaatagt taatacccaa attgcagccc ccatggcatg
     9541 agattgggga gccgtatcgc caaaaccatc cgtattatga tgtgctgtaa aacctctagc
     9601 tccatacatt ttcttagcgg ttagtcttcc cggttctctc attctttcga gcatatcaaa
     9661 taatggatat tctacttctg gtaaatcaca tggacctacc atccaataat tcatttgagt
     9721 attaatatta atcgtatatt tagaacccca aattggattt aattcatcac accatattcc
     9781 ttgaagattg gcaggtaaac cattcggttg actagacgat attaacagat atcttccata
     9841 atgaaataac aagttagtca agtagttact atacttttta gtgttttcaa gaagtagatt
     9901 cgttggaatg ctaagacaat ctttactata gtctagttta aaatcaactc tattaaattg
     9961 ctcctgatat ttttttacat gttcatcttt ttctgtaaag taatcaatac tactaaattc
    10021 tccctgaaga gaagaaatat ctatatttcc ccaataatcc gtcattgatt tgagataaag
    10081 aaatacctct gtagcattcc gaataactat tgtctctccc aatacactta cttcaccatc
    10141 cgtaacctta gaatgacata ctactttaaa ctgaacacct tttctacctc cagcagaggc
    10201 cgacattaaa attgtacttg aatccagttt agatacttcg tcattaaacc gtttatttct
    10261 acccaaatta atgtttaaat ttaatgtgtt ttgaactgat gacactatac ggcaacataa
    10321 aatattctta ttaaaactcg taaaatattc tctttttatt tgtaaattac aactattagg
    10381 ctcaaacaca acattagaaa tagctgtatc taaatctagc tctctttcat acaatgaaag
    10441 agcacaagac tgaatatcta tatgctcaat gtaaagttcc ccaagtaatt catagtggct
    10501 ttgatctctt ggggtagcaa acattgttaa ctttatcaat tcttcggctt tctgaatttc
    10561 tccatctaaa agatattccc gaattttttt aagatgcaat agtgagtctg gattatttct
    10621 atctgacttt cctctatacc aaatagtctc atcgtttagt tgaatacatt cttttgtagc
    10681 tgaaccataa atcataccac ctaaatgacc gttcccaatc ggcaaggctt cattccaatt
    10741 tgaggcagct ttcttatacc ataatttcac tctttacctc tcttccaaaa tggaggtgat
    10801 atcccaaata ccacctccac actttctact acttcaaaat tcctaaaaca actaggataa
    10861 ctccaatagc cataacacta aagattagta caaccggatt ctttcctttt ctaattaatt
    10921 tacacattaa taaagtcaaa gccataggga taaatcctgg aattaatttt gtaatcattt
    10981 cttgaacaga aataacaagt tccccctgct taaattctaa tccaaaatta ataccaacca
    11041 ttgatggaat caaaccaccc actagtacta gccctaatgc tgtcgccata ctcgtaacgc
    11101 gattcaatgt tccttttgta ttattttctt ggataagact agaaccctta gtatacccat
    11161 atttcaaacc gaaatattta acaggaatat taataatatt aaacaatatt aaggcgataa
    11221 agatacctaa agcaccgccg tctttagaat aagacgcacc aatactaaaa cagataggaa
    11281 ctagtgtcag ccagaacaaa ctatctccta gaccagccag tggccccatc aagccaactt
    11341 taataccagt aattgaagct gcaccttcat ttccttcttg ttcttccata gcggaagtaa
    11401 ctccaagaat aaatggtgcc gctgtttgat gagtattgaa aaactcaagg tgacgtttca
    11461 ttgcaggaga agctgaatct ttgtctgggt atagtttttt caatactgga agaattgtat
    11521 atagaaaacc taggttctgc attctctcat agttccatga agaaccatac ataaaacttc
    11581 gtttgaaaac ttttttaagt tcaactttag ttactttatt attcatcata gatcaagatc
    11641 ctcctcaaca tcactacttg aagttgtttc ttgtggttta cttccaatca tatcgtagaa
    11701 gtatgctacc gcaataccaa ctagtgagat cccaatggtt gacattcctc catacacaga
    11761 acaaatgaat ccaatcaaca agaataccca catatttttc ttgagcatca tatttaaaag
    11821 cataccaaaa ccaattgaag gtagtaaagc acctgcagag ttaagtccct gcataacgat
    11881 tggtggaacc ttagcaaaca agtctgccac atattcccct ccaagcataa tagctaggaa
    11941 aattggtaca attttaaata acgtgattaa aaccaaactt gaataatgat aaaaaccgat
    12001 ctttgaataa tctccgtttt tagcatcatt atcagctttt ttcacaaaat aaacatctaa
    12061 agtttttgca agaacatcca actgttgggt agcaactgca attggaactg ctatagcgat
    12121 accagcagtt tctccttgac cagataaaat accaaatgca gtaccaataa tcgcacctga
    12181 aatagtatct ggtggagtgt aacctccaat acctgttaca ccgagccaag ttaattcaag
    12241 agctgaacca ataagaacac cttgggtgaa atctcctaag actaagccaa ccattgcact
    12301 tgtaactaac ggacggtgaa tcataaataa cggtccatta tagtcaatag tggcaataat
    12361 cccaactaat gtcaccagta atgcttgtgt gaatagcata tactgtacct ccttaaatta
    12421 tttttataaa aatttttcca acattgtaac tttatcatta ggaaccattt gaatttcaac
    12481 tctcgttccc ttatcaacta ttttcttaaa ataatatttg tcttcttcac ctagagctac
    12541 acctcccgtt accttttcat tttcctccgt tttactcatc tgtcctacat tgaggtactc
    12601 caattttaaa tttccttcaa tagaatcata cacatctttt ggatttgtat atatcagcat
    12661 tgttctcttt tttattggca cagagtttaa aacttccaca aaccgtttta cactaaagaa
    12721 aacaattttt aaacctaccg gtgcagaaat ctttaaaata gattgtcgtg ttttatcttc
    12781 tgagatgcga tcattaacaa tgataacttg ctcaatatca tactttttta gccacgtagt
    12841 gacaacttga ccatgtacca gacggtcatc aatacgaaca aactctatag acataaatcc
    12901 tcttcctcct ctacgttaag ttgttgttta acattaaaca aactattttg agcattttga
    12961 acaatttctt ctaaattgat ttttgaatca taacttgata ttaattccac taggagaggg
    13021 atattaaacc ctgttacaat atcaactgaa tccaaattta aaaaccgtga caaagccaca
    13081 ttattaggac ttcctccaat caagtcagtc aaaacgataa cctcttgatt tgagtctaac
    13141 agttcatcca cttgattttt aaaataatgt tcaaactcta caatattctc tccaggcatc
    13201 aaacctaatg tcctaactct atcatttgtt gtctcaccaa caaacatttc tgcggtcatg
    13261 agagctccgc tagcaaaatt accatgactg gcaactaaaa ttcctctatt aaacattttc
    13321 tctttcaaca actactcctt tcttaaggat aatattagca taaagtgaag tttctcctgt
    13381 agcaacaata gcataagctt tcttactacg ttcataaaag tcttctcttc taagataagt
    13441 aatcgtttta agatctgtac catgaccttc aatcatctgt ctataggtac cccatatctt
    13501 aggaatatca tcacccgaaa caacgttcat aaactgaatt gaactatcga cgtaactatc
    13561 taatggcatt aaatacagaa tggaatctaa taattctgga atatttacgc catcacaacg
    13621 aattagctta tttgcacatg aggcagaagg ataattcgcg tcagctaata ctatttcatc
    13681 tccatgtccc atttccatta aagtcttcaa taaatctgga gaaatatttt tcggtatatg
    13741 ttttaacatt aatatcctcc ctattttctc tgaccgtatg ttttaaattt ttctgccatt
    13801 aaatccatct cctcatcagg aagaactact ggctctccaa aattcttagc taaacaataa
    13861 atttttgcac aatattcaac ttcttcaaca atattaaatg cattcaataa attttgtgca
    13921 cctgctaaaa ttccatgatt cgctagtaaa actgctctac gaccttccat tgctttagct
    13981 gcattcacag ccaattcttt cgtaccatat gttgcatact cagctacccg aacatctttc
    14041 cctgccactg caatcatata atgactagcc ggaagtggtt ctctgagaca agctaatact
    14101 gttgcataag ttgtatgagc atggataatt gcatcgatat catcacgagt ttgatattga
    14161 atcaaatgca tataccattc gctagatggc aagcgttctc cctctacaac atttccatta
    14221 atatccatca ctacaatatc ggattctttg atttcaaaga aatcaatacc cgacggggta
    14281 attgccatca attgtttttc acgatcgaaa acactgagat tcccacctgt tcctttcgtc
    14341 aaatctgttt ctactagctt cttgccatac ttaattaatt cttgttttac atctgacatt
    14401 cttgtcctcc tcatatcaaa acactaaata tttttcaatt caccaattat ccccccttct
    14461 tgtacaaaac ttaggaaggg ggagggaggc aaatttacaa actctcaatc tttttaattc
    14521 ttttgggagt aataactctc taattgtaga aactcctcaa taacatggtg agcttcttcc
    14581 atccctttta attgtcccat agctatgagc tgcacaacaa tattccccac agctgtaccc
    14641 tcagtcgaac ctgtaagaac ctctttacca gttctatcag caatcatttg gttaaagtaa
    14701 ctggctctag cacctcctcc aatcacatat atcctcttat aaaccttatg agttagttct
    14761 tctagtaact ctatcgcttt cctatacgtt tcagctaggc tttcataaac aatcttaaat
    14821 agttgtccat ctgtccactc tctagtttca tgatgataag ctagatattc tgtcaaagtc
    14881 ttgtgcatat cagattctgt tgcaaattca gttgattcag tatcaatcag aggaagattt
    14941 tctttttctt tctccaccat tgtcctaata tcatcaaaag aataggcttt ccctcttcgt
    15001 tcaaatgaac gtcttagttc ctctatgatc cacaaccctg tacaattctt cagaaatgta
    15061 atcactccat ctttaccgac ttcatttgta aatccataac tgaaggattc ggtagtaaga
    15121 atcggtgaag taagttccac tccaaccaaa gaccaagtac ctgatgaaat aaataaacta
    15181 ccttctgtct taggtactga gacaatcgca cttgctgtat catgactaca aacattcaca
    15241 acaggaatat cgcctaaacc atactccttt tttatccttc caagaacatt tccctctgaa
    15301 acaatttcag gaagtaaaga tgaatccaat tcaaatagtt ttaagatatt ctgattccaa
    15361 ttttgactcc taggatcaaa taattgagtt gttgaagcaa tgcttttttc tgtagcaaac
    15421 ttacctgtca agagataatt aaacaaatct ggcattaaaa gaatcttatt ggtcttatag
    15481 aaagagtcag gagattcttg acgtgcctta aagagttgaa acaaggtatt tatctccata
    15541 atctgatttc ctgtctctga atacagtttt tctaattcag tcatttcaga tatttccttt
    15601 aacactccct ttgttctttc atcacgataa tgaacaggtt gtgataacag cttaccttca
    15661 ttatcaatca gtccaaaatc aactccccat gtgtcaatac cgatagataa aatcttgtaa
    15721 ctagtattag ccaagcggat actttcaaga attttagcta gtagaaagtc aatatcccaa
    15781 gataaatgcc cttttactct aataggtaga ttagaaaagc gatttatttc ttccattact
    15841 agtttatttt cagaaaggta accaacgatt gctcttccag aagtcgcacc taaatctatt
    15901 gctaaaaccg cttccatttt tcttctctct tcgtccttga ttaagtttat tataatcccc
    15961 acattttatt ttttcaatat gtgaacgctt acttggataa tgttcaaatg ttaacccaat
    16021 attcataaaa ataattcaaa ttcctccaat ttgtgctata atatagttga aatgataaat
    16081 taggaggagc ttatgataaa agatgaacgt gtacttgaat tgattgaaat tattaaaaag
    16141 aaaaaaagaa ttgccgtaaa agagctggca gaaatcactt tctccagcac aagtacctta
    16201 cgtcgtgatt taattttctt agaaaatcaa ggtcttatca aaagaaagca cggatacgtg
    16261 accctgtcct ctatgaacac aattgaactt tctcatcaaa tacgggaagg agaaagtact
    16321 aggcaaaaaa gactaatcgc tagtctcgct aaagacttta ttcggtcagg tatgtgtgtt
    16381 tatctggatt ccagtacgac tgtctacgaa ctttgtccct atctttctga acttgataat
    16441 ttgattattt ttacaaatgg tttacatact gcacaaaccc tatctgaaac tgttaaagat
    16501 agctccaaaa tctttatcac atctggcgag gtcaaacatc aatcctgttc cgtggtcaat
    16561 tacgataagg aaaattcttt attagatcat tttaatatcg atttagcatt ttgttcagca
    16621 agaggtattg atgaccaata tgtttatgaa gcttctctca gccaagctat ttcaaaaaag
    16681 aatattattg acaaagccca tgaaaccatc ttactgattg atagctctaa attttacaag
    16741 actggatttt ttaaaattaa tcccctatcc aaatacacaa cctttatttc tgacaccgtg
    16801 ccagatcaaa aattattaga cgcagtcgaa ttatttgatg gagaatgggt ttctgatatt
    16861 caatgaaaat caaataggaa gctagtctca gcttgctcaa agtacagatt tgaaaactga
    16921 tgaagtcaag tcccccatgg acacggcaag acgaagctga catgatgtga agagattttc
    16981 gaagaatact cgttctgtct gctgactgat ttacaaatat tcaccacatg acattatttt
    17041 cttagcaacc ctaaaaacag aggctggaca aaaactcaat ttcaagagaa atggggcaaa
    17101 tattcccaca ataaaacgca tagtatcaag tttttgcaca cctgatatta tgcgtttttc
    17161 tgattttaaa gactttgtcg cctagaccct atatttcaag aattaagtga ccttgatgat
    17221 ctaaatgtat tgtggtatac tatttttgtc atcggttacc gattacgttc ctatgggttc
    17281 gtgagaggag gtgaaactaa tgagccttat catagagctc gctcttacta ttatagcgga
    17341 tgttatagct ggaattatct tgtatttcat ctgcagatgg ctagatagta aggagtagac
    17401 cgaatgacta gcctataaac acccgttaaa tctctaagat acgtcaaaaa agcccttaac
    17461 tacggccata gttaggggct ttggtgttct aatgaacctt atcaattaac tacattttag
    17521 catataatct acaatagttc aagcattaag tgaggttgat gatctaaatt tagtgtggta
    17581 tactattttt gtcatcggtt accgattacg ttcctatggg ttcgtgagag gaggtgaaac
    17641 taatgagcct tataccagag cttgctctta ctattatagc agatgttata gctggaatta
    17701 tcttgtattt cgtctgcaaa tggctagatg gtaagaagta gaccgactga ctagcctata
    17761 aacacccgtt aaatcactaa gatacgtcaa aaaagccctt aactatggca ctagttaggg
    17821 gctttggtgt tctaatgaac cttatacact aactacattc tagcatataa gtcctaatat
    17881 ttcaagagtt ttatttattt tttcaggttc ccttagttct gaaaggtcta taatgaagtt
    17941 agccatctag tatcaaaaaa ccgactagct cttatgaact agtcgatttc tcatcaatgc
    18001 gccaacattt cttgggcgat ttcttggcca gataggttat ctgggtagta ggttggccag
    18061 ttgtccattt cttcaaagag ggcttcttgg cttgtgcctc caaagaagat atggaaatgt
    18121 tctgccttaa ctggggcgat attgtggtca ctaaactgaa catacttgaa ttgtccagcg
    18181 tcagcatctg tggcttcaaa gaggaaacgc acgccacgat tgcctttctt gtaagtcaaa
    18241 attttcttac cgacatactt gtaagtgtat ttcttgcttt gtccaccttg aacaaattcc
    18301 atagtattat cagtaatgtt aatcttagtc acatctgtct gatagccttt tgtatagtaa
    18361 gccttgtact cagcctgggt catcttacca gtcaacttag ccttgtagtc aaagacttgg
    18421 tcaaacgtgc cgtcttcaag gaaaggataa actgattgcc agttacctgc atagtcactc
    18481 aaggtgcggt ccttgacagc tgcatcctcg aagtaaccat tttggactgt cttggtatcc
    18541 tctgcctttt caggctcgat tgctgggcct tcttggtctg ttgtttgttt caaagccttg
    18601 aggtttttct ccatgataga gatgtaattt tctccagcct tggtgtcctc ttctgtcaga
    18661 ctttctaaag gattgaggac atcagttttg acacctgctt cttttgaaag tgtgttagca
    18721 agggcttgtg aggcattttc ttcaaaatag atataggcga ttttattttt cttgacatac
    18781 tctgtcaatt ctgccaagcg agcagctgat ggctctgcat ctggagaaag tcctgagatt
    18841 gcgacttgtt tgagtccata gtccaaggca agatagttaa aggctgcgtg ttgagtcaca
    18901 aagctctttt gttttgcttg agacaagcct tctacgtaag ccttatccaa ggcttgcaat
    18961 ttttcgatat aggcagctgc attcttctca aaggtctctt ttttatcagg ataatctgct
    19021 gacaagctgt cgcggatgtg ctctactagt ttaatggcac gaactggtga taaccaaaca
    19081 tgggggtcaa actcatggtg atgaccttct tctccatggt catggtcccc ctcttcttcc
    19141 tcgccacctg gcaagagcaa catatcgcct gtcgccttga tggttttcac ttttttctta
    19201 tccaaggtat ctagcaattt aggtacccat gtttccatgt tttcattttc ataaacgaag
    19261 gtatctgcat cttggatttt ggtaactgcc ttggcagatg gttcgtattc atgaggttct
    19321 gtcccagcac cgattaggag ttctacatta gccgtatctc ctgcgacttg cttggtaaat
    19381 tcatagacag ggtaaaaggt tgtcacgata ttgagtttac catctgcctg tttttgattg
    19441 gaacaagcca ctaaaaacaa ggcacataga ctggctagta ataagctaat ttttttcacg
    19501 ttcgtctcct atttgataaa acgtcttact aaactgatta gtataaagac agttacaaaa
    19561 ataatggtaa tacttgcact tgcaggtgtt tctgcatagt aggaaatgta aagtcctgct
    19621 accattccca aaaagccaat cgcactggca agcagcataa ccgatttaaa gtttttcccc
    19681 agacgcaggg caatactagc tggcaagacc ataatggtcg ataccagaag agctcctgct
    19741 gcaggaatca taagggcaat agccacccct gtcaccatgt taaaaagaat ggacatggta
    19801 cgaactggca agccatccac aaaggccgta tcttcatcaa aagttaagat atacatagga
    19861 cgaagaaaga gaaaggtcaa aatcaaaaca accgccgcaa tgacaaagag ggaaatgacc
    19921 tgttcttcac tgatagtcac gatcgaacca aagagatatt ggtccaaact cattgaactc
    19981 gagcttttac ccttgctcat gacaatcaga gaaacagcca gacctgttga catgaggata
    20041 gctgtcccga tttccataaa gctcttgtaa accgtacgga gatactccag aaagaccgcc
    20101 gcaatcaaga caatggcaat agtagaaaca gttggagaaa tccccaaaac cagaccaaag
    20161 gctacacctg aaagtgagac gtggctaagg gtatcactca tcaaactctg acgacgcaag
    20221 atgaggaagg ttcccaatac cggtgagaaa agactcatag caataaccgc caaaaaggcg
    20281 cgttgtataa agtcgtaaga taataaacta agcatggctc acctcctggc cattctcatg
    20341 aacgttgaaa caacgccatg gcgagtcttg gttacggact agatgaatat tgcgatccgc
    20401 ataatcctta acttcttcag ggtcatgggt aatcatcaaa acagccttgc catgatgatg
    20461 ggcgctgtgg tgcatgagtt cgtaaaattc atttttactt cctgcatcca tccccgttgt
    20521 cggctcgtct aggataaaca catcagggtc agaagcaaac atacgcgcaa ttaccgctcg
    20581 ctgcttttgt cccccagata gagaccccaa gcgtttgtct cgatgttccc acatgccaac
    20641 tgagtccaga ctggccttga tatgctcctc atcatgagca ttcaaacgac ggaaccagcc
    20701 ttttctcgga tagcgacccg acttgacaaa ttcatagacc gtacttggaa aaccagcatt
    20761 aaaactggca atttgttgag gaagataggc tattctcaat ttcttacctt gcgtatttgt
    20821 ctttgaaata gccacctttc caatgcgtgg ttgcagaatt ccaagactgg ccttgatgag
    20881 cgtcgtctta gccgctccat tttccccagt caaggtaaca aattccccac tatcaacact
    20941 ataattgata tgttcaagaa caggctcctt atcataatag aaggacaaat cctctaccgt
    21001 aatatatctc attatttgat ttctcctact aaagcagtca aaaaccgctg aatcactttt
    21061 tgttcatttg gagtaaactg agtcgccact tgttcatagg ttaaaagtgt atgctcatgg
    21121 tgatggtggt gctcctcagc gattggacga gccaagtcag tcaactgata aaaaatcaca
    21181 cgcgcatctt tagaatcttt agatgtttcc aacatccctt ccttgaccaa agacttaatg
    21241 gccttggtaa ctgccgcctg actgacattg agacgacggg ccaattctga atttgttaaa
    21301 gattcctctg acaagagcat aaggatatgc tcctgagtat tggtcagggc cacctcgcta
    21361 gtgcaatgac ctattaggat ttcatgctga ttttccgcct gcaaaatcac ctcattcaaa
    21421 aaagcattga tatcctttgc tagctgtctc atatctgact cctttccttt tagacttctc
    21481 ttttttaaga gaaaaatact attctttgac attttgttta ccagttaatt atatcacaag
    21541 caaaaaaaga gtcaagaaaa aacgtgaaaa ctagtttcat tcttgaactc ttctatatta
    21601 tattatctat tgaaattctt tgacatctcc atcataagtc gcccaatctt tgctgaaaaa
    21661 gcgctcattc agatggtaag tcggagctgg tgtgggattg gataggaaag gatcaactgc
    21721 cttgtcaaaa gccaaccaac ccaaccaacc aaggtgaatg gtgtccttca taaagaaagg
    21781 ctccccaccg tccttagaaa aatctgctat attggtaaaa ccttgacttt ctaactggta
    21841 gcgaatcttc tgcaccgttt gttggtacat atcctctcgt agaccagcat agtccatcca
    21901 ttttttatta acaggtggaa tgataaaaat cgggtttacc ttagatttag aaaactgtgt
    21961 taaaaccaac tgcaagtcat tatactctgg cgacttgaga taggtaaagc ttttctgaga
    22021 atcctttaat ttcttcaaat ccttcttgat ctgctcatta tagaaataat tttccattcc
    22081 catctcatta ttggaagtat ttttttcagc atctgctttg acaacatctt ctattgcttg
    22141 ataagaaaac tggtctggca agatttttaa atacttagct acatgcttat cgtagttaac
    22201 atagcctcta accgaaaact gaccaaaaaa ggaggcttgg cgttcattaa aacgagccaa
    22261 taattcaatc atttcattgt ctgctgtcga caattctcct ttacttgcca acttctgaac
    22321 caggtccttc atagctacgt ttgggaactg ttgcagtaag cgagtcgctg catattgact
    22381 agcctgatcc ccagattgat gtttcagaaa actagtcaac tggtctccat taaaatactg
    22441 ctggaaggct gctggatcat agccattttt actgaaccac tgaggtgaga taacatacac
    22501 aacttgttta ttctccagct gtggtaacat ctgttgcatt ccaaaatatt ggttaagcga
    22561 tgcagctccc ccctgtccta aaagataagg acggtaggaa cgattgtatt tctcagctaa
    22621 taccgcagga tgagcaccgt caaaacgaag ccattcacta gagccaaaga agggaacaaa
    22681 acgcacattt ggatcagata gtgctctgac tttttgactt cgctccttaa aactatcgat
    22741 agtagtagcc actgctgaac gcttttcagc tcctagatta tgatgcatct cagtaggata
    22801 aaagaaaatg agcagaaaaa ccaacaaacc agcgatcaag accggtccga agatcatcca
    22861 taagcgttta agcattttgt agctccacaa taccagctat gattttatta gctgtattcc
    22921 agtcgtcacg accaaactct gttacaggga cacgaatgtc aaaacggttc tcaatctcca
    22981 caatcaactc aaccgttccc atactatcca agacacctgc atcaaaaaga tcttcatcca
    23041 tcatgtcaga aacatcttcc ataaacaact catcaataat ttcaataact tctgatttga
    23101 tatccatatt ttatttcctt ttatttttta aaccatagat tattcaagaa tccagaaaag
    23161 attaagaatg acaacatgac aacatggaaa gtgacaacca tgccaagcaa ctgaatccag
    23221 cgattctcag gtagggcagc cttccctgct tttttccgtt ccttattgag cgtttttttc
    23281 ttgcgaaccc aggcatcatt gatgaccaag cctagtccat gaaagagtcc ataggcgata
    23341 tagtaccagg tcacaccatg ccaaaatccc ataatcagca tatttacaat gtaggccatg
    23401 cttgaggtta cattacgatt tttaaagact ttctttctgg ttaacaccat caccattcgc
    23461 ataaagacaa agtcacggaa ccagaaggac agactcatat gccagcgatt ccaaaactcc
    23521 tttaaatccc ttgataaaaa gggcttgtta aagttgatag ggctacggat tcccatcaag
    23581 tttgagatgg ccaaagcaaa catagaataa cctgcaaagt caaagaagag ctccagacca
    23641 aaagtataca taactgccaa ggcatagaga ttaaagaagc cacctgactg caaggctaaa
    23701 ttcttcagag gaggtagtaa ggtctctcct aaaacatgag ctaggataaa cttatacaaa
    23761 aagccccaca tgatatagcg gacagattca tccagcatat ccatcaactc atctcgctca
    23821 ggaatagcct gataattttc attaaatcgc ttaaagcgat cgattggacc actcgagaaa
    23881 gttggcatga agagaaggaa acggaggaat tcccagaggg taaaatcctt aatcactcca
    23941 tctctcagct cgatgataat cccaaccgaa cgaaaggtca ggtaagaaat tcccaagaac
    24001 ccaagcaaag actgcgttcc attgatagct ggttgcacct tgacaaagat aatcggaagt
    24061 agggacagaa aactaactaa gtagaagacc cacttgccat ccttgctttt tcgataatgc
    24121 ttgtagaaaa gcaggagcaa tatttcccag caaaggtaaa tacccaaggc agctagttga
    24181 ttggtctttc cacccaccaa catggtgaca ataaagaaga gacttaccaa cacttcatac
    24241 caggcaaagc gtttcttgaa aaagaggcct ataaagatgg gcaaggttgc agcaatcaca
    24301 taaacaaaat actgaggatt gccatatggc tctaaatgag gaagctgttg aaaaaactcc
    24361 atcatctctt attcacctcg ttaatcaatc ctttgatgtc aatctttcca tttggagtca
    24421 gtggcaaact gtctcggtaa aggaatttag atggcatcat gtaggacatc atgatgtctg
    24481 tcaggtcttc cttgatggcc ttggtaatat cgatatctcg ctcaaactgc tcacgaacac
    24541 tgtcttttaa gatgacataa gccaatagat tttgtacctt gtggtccttg ttatagcgcg
    24601 gtactgcgac agcagattcg ataaagcgag acttgttgag gttttgagag acatcttcta
    24661 actcaatgcg gtaaccgttg aacttaatct ggaagtccat gcgtccgccg tagagaagca
    24721 agccctcatc tgttatggtt cccacatcgc ctgtgtgata ggctggcaga ccttcaaact
    24781 caaagaaggc ttctgctgtt ttttcaggat tgttcatata accttttgaa acagctggcc
    24841 cagaaacaat gatttctccc tgttcgccat ttggcagttt atttccttcc tcgtcaatga
    24901 taaaggttgg agaatcagcc ttggtatagc cgattggtag gcgtttgaga gtcgctaaca
    24961 tctcgtctgt cacggcaact gctgacagag ctactgtcgc ttctgttggg ccgtaagcat
    25021 tgatgatacg ggcatttggg aaacgctcgc gcagtttttg agctgttttg accgtcaatt
    25081 cttcaccatc aaagtagaaa tgcgtgattc caggcatttt ttcactgttg aagtattcag
    25141 acaacatggc catatctgca aaggatggtg ttgatgtcca gatagcgatt ggcaatgaaa
    25201 agatagccgc aaagagttgc ttaaagtcct gagtgatgac tgaaggaaga gtgaaaagcg
    25261 taccaccaag tgccaaggtc ggtgcccaat acatgacaga caagtcaaaa gaataaggtg
    25321 gctgtgccag catttgcgga cgactcggtg tcgcaaattc cttatccgta atcatccagt
    25381 ttgtaaagct gaggagatta tcatgtgaaa tctgcactcc cttaggctta ccagtcgtac
    25441 cagaagtaaa gataatgtag taattatcat ctcccttgac tggatgcgtg atttcatagt
    25501 tgttcccttg ggcaaaggct tcttgaacct gagctagatt tatcattggt gtagaaacct
    25561 gctccaaggg aaaggctgaa atggcaataa tcaagcttgg ctctgctact tctaaaatag
    25621 ctgaaactcg ctccaaggcc gaatggctat caattggaat gtaggcatga cctgacttag
    25681 tcagcgctac aaaggttgcc aacatttcat attcttggcc accaaaaaca accacaggag
    25741 acttctcagg caagcctagt tggtcaatga ctgcagccaa actatccgaa tcagacttta
    25801 aatcgccata agtgtgttcc tgccccaaaa cattatagac aggatagcta ggctgtgtct
    25861 gagcaaaatg ctcaatggtt tcaatcatat ctgctattgg tttatttgac acaataggga
    25921 ttctccttca agttaaaatt cattatagat aaagcttcct tgaccctgac caagatagct
    25981 aaagaagtaa agcagcccta gaaagataag aaaatacaag gctgtccgac caagaaagag
    26041 gtacaattct tttctctgtt tcatcaagaa aaaccattca tttctgtaat ttttcgctaa
    26101 aataagagtg attcttacta gcttattttt ctaccattgt accactttat atagtatctt
    26161 ttcaattgtt taccgtatgt ttccaataga tttcagctta ttttaaggat tatgcggttt
    26221 ttctatatct atttcaaaag aaaaaagcct gagattttca tctcaagctc tagcaataat
    26281 agttattttc taaactaaaa aagtgagaat acaagcacgg ccaaggctgc accgataaca
    26341 ggtcccacaa caggaatcca agcataagac cagtctccgt ctcccttgtt tgaaattgga
    26401 aggatactgt gcatgatacg aggtccaagg tcacgcgcag gattcaaggc ataacctgtt
    26461 gtcccaccta gcgatagacc gataccgaca atcaaggtac ccactgcaaa ggttccgata
    26521 cctgcctgaa aatcgtaaag acccaaagca aagattgtca acaccaaaac aaaggttcca
    26581 aggatttcgc taatcaagtt tgatacagta tccttgatgg ctggtccagt actgaaggtt
    26641 gccaggatat tgcctgcatt ttcttctgcc tcatagtgag gtttgaattg caaccaaacc
    26701 aaaatctgac ccagcatagc ccctgcgaac tgggctaaga tataaggcaa aacggaagcc
    26761 caaggcaagt caccttttaa agctacacca attgtcacag ctggatttaa atgagctgga
    26821 ctgagcttgc cagatacaaa tactgcaacc gcaactgcaa tcccccaacc catagtaatc
    26881 acaatccaac ctgagctatt gctcttggtt ttaggaagaa ccacacctgc aacaacacca
    26941 tttcctagaa gaatcaggat taaagtccct agaaattctc caaataattc attcatcatc
    27001 tttctgtctc cattaaaaag aagggacgag cgacaaggaa tgctgccctc cacctctttt
    27061 attttttctt aattttttaa ttctgctaaa tcgttgttag cgagagctgc ttcgacatca
    27121 gcacggtaag ttgctttttc ttcttctgtc cagtcataga atcgtcccat ttcatccaaa
    27181 actggctcaa cgatgctatc caagctatca cgcataaaga gcatatggtt ggtacgacga
    27241 agaaggaagt caactgggct aagagccaac tcgttgcgca ttgcatagtg aagggacaaa
    27301 gtatctgcca agctgagtcc tggcgcttgt tccaagctgt gagcaagtgc aaagactttc
    27361 ggtgcatttg aaccgtaaag atttgccaga tagtgagctt ccttgctatc caaaccacgt
    27421 gatactccaa gttgcgcaaa ggcttcgatt tctgaatcca catttgctgg gttcaattct
    27481 ccacctgaaa cagggtaagt tttagaattg atcaatttaa agctacggtc aaattctgct
    27541 ttgaggatgt caaccacgcg ctccatagct ccttcagcca tcttacggta gtctgtgatt
    27601 ttaccgccag caagagtcaa aagaccattg tcatcacggt ccaagctaga cccacgagaa
    27661 actgcagatg gatccaaata tttctcagat gtgctacttt caagcttgct gacagcagac
    27721 tcaacatctt cacgtgtttt ttctttggag agataagatt caacagtcgc aatcaagttg
    27781 tcaaagcttt catcactgat ggtaccgtta tttccaccat tatagtcaga ggcactgttc
    27841 cctgcaatca atggacgaag acctgcccag ctgctttcga tatcatcaat ggtgatgttg
    27901 gattctggaa agcggttgtt gacaatgcca agtagataat ctacatcttc ttgagttact
    27961 tttggatgct ccaaatcacc tgtgtagtct gtatcagttg taccaaagta agtcttgttt
    28021 tcacgtggga gaacaaagac catacgaccg tcacccaaac ctgtgtcgaa gtaaactggc
    28081 tgtgaaacct tgattttgct tgaatccact accaagtgaa ctcccttagt tgggcgcatt
    28141 tgtgagaatt gcgttccctt attagacaaa ttacgtactt tatcactcca aggacctgtt
    28201 gtattaataa ccagacgggc cttgatttca aatacttggt ctgtcaagag atcacgagct
    28261 acaacacctg taatcttgcc actttcgtca aagaggaagc cttctgcctt cacgtggttg
    28321 gcaatgaggg caccgtcttg gttggcacgt ttgatgtttt caatcacgag acgcgcatcg
    28381 ttgttacgga agtcaagata cactccacct cctaccaagc cttccttctt caagtttggc
    28441 tggcgttcca agacttgatc cttgctcaaa accttgttcg cagctgacgt gttgctcaca
    28501 cctgctaaaa ggtcgtacaa gtccatggct actttaagac ggaagaggct aaaggttgct
    28561 ccatcttcat cgtaaactgg taagagcatt ggatctgatt ttggaatgtg tggagcgatt
    28621 tgttgaacca ctgcacgttc agaaaccgta tctgagacca cttctacgtc aaattgtttg
    28681 aggtaacgaa gtcctccgtg aaccaatttt gttgaacgac tagatgttcc ttctgcaaag
    28741 tcttgcattt caatcaaacc agtctcaaga ccgctagctg ccgcctgcaa ggctacacca
    28801 gctcctgtga ttcctccacc gataatcaag aggtccaggg tacgttcctg cattttttta
    28861 attgacaatt cacgtgtttt ctttgaaaat tccatattta cacactttct aaataaatcg
    28921 ctttattctg ccagtattag tcgtctactt ccgcaaagac ttgagttgct ttcacagcct
    28981 tcttccagcc cttgtagagt tgttccttgc gagattcgtt catagatggc tcaaagagtt
    29041 ctcctgtctc gttcaagagt ttcaactcgt ccaagtcttt ccagtaccct actgacaaac
    29101 ctgctaggaa ggccgctcct agagctgttg tttccaggtt tttagcacgt gcaatgtcaa
    29161 tgcctaaaat atccgcctgg aactgcatga ggaagttgtt catggctgca ccaccatcca
    29221 ccttcagtac ttgaatggcg gtctgagtat ccacttgcat ggtgtcgatg atatcacgca
    29281 cttgataagc aatagattgc aaagtcgcct tgataaagtc ttctttgctt gttccacgag
    29341 tcaaaccaaa gacggaacca cgagcatttt ggttccagta tggagcgcct agacctgtaa
    29401 aggctggaac gacataaact tcatcgttgt tgtgagaatc acgagcgtat ttttcagatt
    29461 ctggtgaatt ttcaaccatg cgaagaccgt cacgaagcca ctgaatagca cttcctgcga
    29521 tgaagataga accttccaag gcataataaa ccttaccgtt gattccgtaa ccaatggttg
    29581 tcaagaggtt gttttcagac aactgcatct cttccccagt attcatgatg atgaaagagc
    29641 ctgttccata agtattctta accatacctg gctcaaaagc caactgtcca aagagggctg
    29701 cttgttggtc cccagccata cctgagattg gcacctctcc accgtagaaa tggaatggag
    29761 ctgtcttgcc gtagatttcg gagttagaac gaacttctgg aagtatagcc ttcggaatgt
    29821 taaggatttc caaaatctca tcatcccatt tgagttcttt aatgttataa agcatggtac
    29881 gagctgcatt tgagtagtca gtcacgtgag ccgcaccgtc agtcaatttc caaaccaacc
    29941 aagtatcgat agtaccaaag agcaattccc ctttttctgc tcgctcttga gcaccttcta
    30001 catgatccaa aatccaacga accttggtag cagagaagta agcatcaata atcaaaccag
    30061 tcttttcatg gaatttttcc acataacctt ggctttttag ttgctcagcc aaaggtgctg
    30121 tctggcgtga ctgccaaacg atagcattgt agataggaag tcctgttttc ttatcccaga
    30181 caaccgttgt ttcacgttgg ttggtaatcc cgattgcctc gatttgattt ggcttgacac
    30241 cactttcgat gaaagcaccc gcaataactg actgaacaga gttccaaatt tcattggcat
    30301 tgtgctcaac ccaacctgcc tgagggaaaa tctgggtaaa ctctttttga ctcgagctaa
    30361 ccttttcccc ttttttgttg aaaatgatgg cacgagaact tgtagttccc tggtcaatgg
    30421 ccatgatgta tttttcttgt gacatgtact gtcctcctga taaagatctt gaggtgtttc
    30481 ctctttacac ttactagtat acaaaataaa gcgctttctt gtttatcaac tttttttaat
    30541 ttttaaaaaa atgtgaggag attgtgtgaa tttcacaaaa aagacctgga ttaaccaagc
    30601 cttttaagtg aataataact ggcgaatcgc taccaaatcc tccatatcca agtcattttt
    30661 taaataatag actggtgtct gttccttctt atgaatcggg ttattggtaa ccagcaaatc
    30721 ataatgccga ctagggtcat aagcttcaat ggtaataaaa cgattgtatt ccaaataccg
    30781 tttcaaaatg gctgccatcc ttgaaaagac aagaaaacca gatgtcaaat ccagaccaat
    30841 ccgcatatgc tggccaccgt tttcagccat atattcgatt aactggagcc attcccagag
    30901 aatcttctta tctaaatctg tcccctgttg aaaagtaggt agagcatgaa aaatctcctc
    30961 tgctgtctct ttaaaatcat gttccatcag taaatatgga tgacgattct ctaactggta
    31021 cttgtagcga tcctgtaaaa tatagccctt atagagatag acttgagcac aaagctgact
    31081 gagttcatag gtgacatggt cctctgtata atcccccaat agttcctcct tcttcatttc
    31141 ttgaatcaat tgcgtcagta aatctgccaa ctgccctcca aaaccaagaa tatactccat
    31201 agtatgaaga ggaagaatgc gatgagatag gagaaaagag aagaatatca tcatctcacc
    31261 atcctcaact cctagtggaa tatgttgccc agcaaaaaag gacggaacct ttctcagcaa
    31321 acgaagataa aagatattgt caaaataccc tcgcattttc tcttctatga cttgaaactg
    31381 acaagcattg acccgaagac gttgttgact gatgtgagcc cagagaacca agtccaattt
    31441 ctgccccaca gacaaacttg caccgcagat ttcctctaaa ttggcaatct cctgttttct
    31501 ctctggtttc tgcatgtgac cttcccattc ctgactcgac cagacctttc ggaaaagaca
    31561 gaaatagaaa tagcgaatct gatgctctgg acctcgccaa cgtccatttt ggatggataa
    31621 atcaaattct gacagaatct gatttaaacc agccaagtga cgaccaagcg tagcctcgct
    31681 aatcaccaat tcttgagcca gctgatgggc taaaaactgt tggtggtaga gaagataaac
    31741 caaaatctgg tatttaacag cactctccaa aaataagctc cgaatatctc tccccttggt
    31801 agctgcaccg atagacagac gcaaattttc attttctgag tgaatagtca gctctaagcc
    31861 actatccaaa gccttgtcat tgagcagggt gacatatttg gttagggttg cttttgaaaa
    31921 tcctgtttct tccattacag ccttgacggt cgtctgagac tcttgtaata gaaaggaaag
    31981 gattgaaaat tgaccacact cagctttctc catcaaatct cctaaataca tttgttaccc
    32041 ctttcatttt ctaccttaag catagcataa atcttacaaa tgctgaaata atctgtttct
    32101 ctttttattt tcatgctgat ttcctggtcc attatcctga aaatcagtaa acacacggct
    32161 ccccctctgg gcatttttat gctaaaatag tagctatgaa taaaattatt aaaactatat
    32221 cagaaagcgg agcctttcgt gcttttgtcc ttgacagcac ggaaaccgtc cgcactgctc
    32281 aagaaaaaca ccaaacccaa gctagctcaa ctgtagcgct tggtcgaact cttatcgcta
    32341 gccagattct cgcagccaat gaaaaaggaa ataccaaact tacagttaag gtgttgggat
    32401 ctagctctct aggtgctatt atcaccgtcg ctgataccaa ggggaacgtc aaaggctacg
    32461 tccaaaatcc tggtgttgac atcaaaaaga ctgcgactgg tgaagtccta gtcggacctt
    32521 ttgttggaaa tggtcaattc ctcgttatca cagactacgg tactggaaat ccttacaact
    32581 ctataactcc cctcatctcc ggagaaatcg gtgaagacct tgccttttac cttactgaaa
    32641 gccaacaaac gccttcagcg gtcggcctca atgtcctttt ggacgaggaa gacaaggtca
    32701 aggttgcagg tggtttccta gttcaagtct tgccaggagc caagaaagaa gagattgctc
    32761 gctttgaaaa acgcatccaa gaaatgccag ctatctctac tcttctcgaa agcgacgacc
    32821 atatcgaagc cctcctcaag gctatctacg gggacgaagc ctacaagcgt ctttctgaag
    32881 aagaaatccg tttccaatgt gactgtagcc atgaacgctt tatgaacgct cttgccagcc
    32941 ttccaagctc agacttacag gaaatgaaag aagaagacca cggggcagaa atcacttgtc
    33001 aattctgcca aactacttac aactttgatg aaaaggacct ggaggaactc attcgtgaca
    33061 aatcttaata caccttttat gattggcaat gttgagattc ccaatcgtac cgttttagcg
    33121 cctatggctg gcgtgaccaa ctcagccttt cgtaccatcg caaaagagct cggagctgga
    33181 ctcgttgtaa tggaaatggt ctctgacaaa ggaatccaat acaacaacga aaaaaccctg
    33241 cacatgcttc atatcgatga gggcgaaaac cctgtctcta tccaactttt tggtagcgat
    33301 gaagacagcc tagcacgcgc agcagaattc atccaagaaa acaccaagac cgatatcgtc
    33361 gatatcaaca tgggctgccc tgtcaacaaa atcgtgaaga acgaagctgg agctatgtgg
    33421 ctcaaggatc ctgacaagat ctactctatc atcaacaagg ttcagtctgt ccttgatatc
    33481 ccccttactg tcaaaatgcg taccggatgg gcggacccat ctctggcagt agaaaatgcc
    33541 ctcgctgctg aagctgcagg tgtttctgcc ctcgccatgc atggccgtac ccgtgaacaa
    33601 atgtatactg gccacgcaga ccttgagacc ctttacaagg ttgcccaagc tctaaccaag
    33661 attccattca tcgccaacgg tgatatccgt actgtccaag aagccaagca acgcatcgaa
    33721 gaagttggtg ctgacgcagt catgattggc cgagctgcca tgggaaatcc ttacctcttc
    33781 aaccaaatca accattactt tgaaacagga gaaatcctac ctgatttgac ctttgaagac
    33841 aagatgaaga tcgcctacga acacttgaaa cgattgatta acctcaaagg agaaaacgtc
    33901 gccgttcgtg aattccgcgg cctcgctcct cactatctcc gtggaacatc tggcgctgcc
    33961 aaactccgtg gagccatttc acaagctagc accctggcag agattgaagc tctcttgcaa
    34021 ttggagaagg cttaatagtt taaaacccgt aactctctta aagagtctct tgagtgccgc
    34081 cattctttcc tcatcaaaaa aactccgtag tctctagcgc cataaatccg gctagagatt
    34141 acagagttat tttttaatct aaacttccta caagggtata gtatctactg aaaggatatg
    34201 gtatttgtag ggaatacttt aaagagttct tacaggaagc cagcattaac gagttacatt
    34261 aggtttagtt tacccattta ccattggcat tgactctata gccacctaca gttgtgttga
    34321 ctgcaagggc acctgagcca ttgacatagt accatttgtc tgatactttg aaccattggc
    34381 tttctttcat agcccctgat gcttcaagat agtaccatgt atctccatct ttcagccaac
    34441 ctgttgccat cgaaccgtta gcatt
//
LOCUS       DAVHKZ010000021        34098 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000021 DAVHKZ010000000
VERSION     DAVHKZ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34098
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.021"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(97..499)
                     /locus_tag="VVO74_001209"
                     /pseudo
     CDS             complement(97..499)
                     /locus_tag="VVO74_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(575..1015)
                     /locus_tag="VVO74_001210"
     CDS             complement(575..1015)
                     /locus_tag="VVO74_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5695232.1"
                     /translation="MKAPIPKAPLAHSLGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLREKLLEQALLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHDQRRSGSVVQEFLGNYSGYMHCDMLRQ"
     gene            1006..1313
                     /locus_tag="VVO74_001211"
                     /pseudo
     CDS             1006..1313
                     /locus_tag="VVO74_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1336..1686)
                     /gene="tnpB"
                     /locus_tag="VVO74_001212"
     CDS             complement(1336..1686)
                     /gene="tnpB"
                     /locus_tag="VVO74_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU5695233.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKINLSESRDFY"
     gene            complement(1667..1852)
                     /locus_tag="VVO74_001213"
     CDS             complement(1667..1852)
                     /locus_tag="VVO74_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695234.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2156..3718)
                     /gene="guaA"
                     /locus_tag="VVO74_001214"
     CDS             complement(2156..3718)
                     /gene="guaA"
                     /locus_tag="VVO74_001214"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU5695235.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3860..4558
                     /locus_tag="VVO74_001215"
     CDS             3860..4558
                     /locus_tag="VVO74_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU5695236.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQISYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4601..5497)
                     /locus_tag="VVO74_001216"
     CDS             complement(4601..5497)
                     /locus_tag="VVO74_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU5695237.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILHIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5506..6441)
                     /locus_tag="VVO74_001217"
     CDS             complement(5506..6441)
                     /locus_tag="VVO74_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU5695238.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSAPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARFLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6438..7163)
                     /locus_tag="VVO74_001218"
     CDS             complement(6438..7163)
                     /locus_tag="VVO74_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEU5695239.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7247..7882)
                     /locus_tag="VVO74_001219"
     CDS             complement(7247..7882)
                     /locus_tag="VVO74_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU5695240.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEKYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(7884..8711)
                     /locus_tag="VVO74_001220"
     CDS             complement(7884..8711)
                     /locus_tag="VVO74_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU5695241.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8733..9659)
                     /locus_tag="VVO74_001221"
                     /pseudo
     CDS             complement(8733..9659)
                     /locus_tag="VVO74_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809127.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            10310..10921
                     /locus_tag="VVO74_001222"
     CDS             10310..10921
                     /locus_tag="VVO74_001222"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU5695242.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10966..11694
                     /gene="rlmB"
                     /locus_tag="VVO74_001223"
     CDS             10966..11694
                     /gene="rlmB"
                     /locus_tag="VVO74_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU5695243.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(11733..12644)
                     /gene="trxB"
                     /locus_tag="VVO74_001224"
     CDS             complement(11733..12644)
                     /gene="trxB"
                     /locus_tag="VVO74_001224"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU5695244.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12710..12934)
                     /locus_tag="VVO74_001225"
     CDS             complement(12710..12934)
                     /locus_tag="VVO74_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU5695245.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAGARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13012..13755)
                     /locus_tag="VVO74_001226"
     CDS             complement(13012..13755)
                     /locus_tag="VVO74_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU5695246.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13755..14555)
                     /locus_tag="VVO74_001227"
     CDS             complement(13755..14555)
                     /locus_tag="VVO74_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU5695247.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14713..15069)
                     /locus_tag="VVO74_001228"
     CDS             complement(14713..15069)
                     /locus_tag="VVO74_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU5695248.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLSVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15082..15594)
                     /locus_tag="VVO74_001229"
     CDS             complement(15082..15594)
                     /locus_tag="VVO74_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU5695249.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15594..16088)
                     /locus_tag="VVO74_001230"
     CDS             complement(15594..16088)
                     /locus_tag="VVO74_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5695250.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16223..16669
                     /locus_tag="VVO74_001231"
     CDS             16223..16669
                     /locus_tag="VVO74_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU5695251.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMINNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16666..17313
                     /locus_tag="VVO74_001232"
     CDS             16666..17313
                     /locus_tag="VVO74_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU5695252.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKNVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(17334..17915)
                     /gene="pdxT"
                     /locus_tag="VVO74_001233"
     CDS             complement(17334..17915)
                     /gene="pdxT"
                     /locus_tag="VVO74_001233"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU5695253.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLLIREAILSGLPVFGTCAGLILLAKEITSQKESYLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(17916..18791)
                     /gene="pdxS"
                     /locus_tag="VVO74_001234"
     CDS             complement(17916..18791)
                     /gene="pdxS"
                     /locus_tag="VVO74_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU5695254.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(18943..20322)
                     /locus_tag="VVO74_001235"
     CDS             complement(18943..20322)
                     /locus_tag="VVO74_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU5695255.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20616..21539
                     /locus_tag="VVO74_001236"
     CDS             20616..21539
                     /locus_tag="VVO74_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU5695256.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     IFWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21599..22204
                     /locus_tag="VVO74_001237"
     CDS             21599..22204
                     /locus_tag="VVO74_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU5695257.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22223..23467
                     /locus_tag="VVO74_001238"
     CDS             22223..23467
                     /locus_tag="VVO74_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU5695258.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(23583..23840)
                     /locus_tag="VVO74_001239"
     CDS             complement(23583..23840)
                     /locus_tag="VVO74_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU5695259.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(23882..25918)
                     /locus_tag="VVO74_001240"
     CDS             complement(23882..25918)
                     /locus_tag="VVO74_001240"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU5695260.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKEIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGGRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKKIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26130..27047)
                     /gene="glyQ"
                     /locus_tag="VVO74_001241"
     CDS             complement(26130..27047)
                     /gene="glyQ"
                     /locus_tag="VVO74_001241"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU5695261.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(27415..28176)
                     /locus_tag="VVO74_001242"
     CDS             complement(27415..28176)
                     /locus_tag="VVO74_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU5695262.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFFTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(28449..29291)
                     /locus_tag="VVO74_001243"
     CDS             complement(28449..29291)
                     /locus_tag="VVO74_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU5695263.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYHAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(29405..30796)
                     /locus_tag="VVO74_001244"
     CDS             complement(29405..30796)
                     /locus_tag="VVO74_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU5695264.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKSFSDQDLSAWNFDYKDS
                     QIILYSSPVLENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31031..31408)
                     /locus_tag="VVO74_001245"
     CDS             complement(31031..31408)
                     /locus_tag="VVO74_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU5695265.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMSYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            31641..32618
                     /locus_tag="VVO74_001246"
     CDS             31641..32618
                     /locus_tag="VVO74_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU5695266.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYSKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGTLFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQDPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            32615..33697
                     /locus_tag="VVO74_001247"
     CDS             32615..33697
                     /locus_tag="VVO74_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU5695267.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTLIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGSEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(33761..>34098)
                     /locus_tag="VVO74_001248"
     CDS             complement(33761..>34098)
                     /locus_tag="VVO74_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5695268.1"
                     /translation="LIAGGCNTEWMNVFLEELSQAYPYDYFLLVMDNAIWHKSSTLKI
                     PTNIGFAFIPPYTPEMNPIEQVWKEIRKRGFKNKAFRTLEDVIQGLEKEVIKSIVNRK
                     WTRMLFESR"
BASE COUNT        10108 a         7642 c         6151 g        10197 t
ORIGIN      
        1 agctcttgct ttagctcctt caaaactttg agaaaaaacc accctcgctt ttttaaactg
       61 agcttaggct aaaagagtcc agtggactct tttactccgt cccataacca atgatttaat
      121 ggcgcgttca gctagattat tggaaaggac cagatgtccg tcttttaaaa tggtcttaaa
      181 ggtttcttca tacttgaggc tgtattcaat tgcccttcct ggttttgaac ctgctaaaac
      241 tgactgacgg cggcaccaag caaagaagtc ttccattaag ggctggacgt ttctgtagtc
      301 gttcatcagc tggcaaagcc tcccagtctc tttccaaggc aaataactgg tcacgatagg
      361 ctaaaccttt agctcctaag gatgatttat ctgcttgctt gggggtcgct tcaaaaaatt
      421 tccttctcac atgcgcccaa catccaacaa gttcagcttc ttccagttga cgataagctt
      481 ctagcggttc gcagtttacc aagcttagcg tcgccttgct cctaaacctt agactgctat
      541 cgcataggca gaactagagg actaaagttc taagttactg ccgcaacata tcacaatgca
      601 tatagccaga ataatttcct aggaattctt gcactaccga accactccga cgctgatcat
      661 ggtggtacag cgtaatccct tgtttctcag ctttcccaga caaaaaagtc caatagtaag
      721 tcagctgact atcactttct aagacccgat aagaggtttc atctgcatga agaagagctt
      781 gttctaacaa cttttctcgt aaaaggttat aaaggggctc caaatagtat tgactcgtct
      841 tgatatgcca attagagatt tccttacgtg tgattggtaa acccatccta gcccaatctt
      901 cttcttggcg ataattgggt accttcagat taaacttctg atggatggtg tgagcgataa
      961 tagaagctga gccaaggcta tgcgccaaag gggctttagg aataggagct ttcacaagct
     1021 tatccagatg attatctttt actcgttatg gacaatgcta tatggcataa atcaagtacc
     1081 ttaaagattc cgactaatat tggctttgca tttattcctc catacacacc agagatgaac
     1141 ccattgaaca agtgtggaaa gagattcgta aacgtggatt taagaataaa gcctttcaaa
     1201 ctttggaaga tgtcatgaat caacttcaag atgttataca aggactggag aaggaggtga
     1261 taaagtccat cgttaatcgg agatggacta gaatgctttt tgaaagcaga tgagtataaa
     1321 aagaaagtcc tcatttcaat agaaatcacg actttctgat aaatttattt tgggagtgat
     1381 agaaaagccc ttcataagcc aatctacttg ttcaggtgtg agagctttga catccttttc
     1441 tgtactgggc caagtcagtc tgccgttctc aaagcgttta tatagtagcc aaaatccttg
     1501 accatcccag taaagggctt taaagcggtc tttacgtcca ccacaaaaga gaaaaacttg
     1561 accggagaaa ggatccaatt caaagtgggt tttaaccaga taagccagtg aatcgattcc
     1621 ttgtctcata tcagtcttcc cacacacgag atagacctgc cctaggctag atagatgaat
     1681 tgtcatagag caacacctta tccaaaagct gttctaccat ttcgagattg agagattgaa
     1741 aaaaacttac ttcaagcttg ccaatacgaa ttttaagcag aatatcattt ctctttttag
     1801 aatcaaaagg acgagattgt ggaatctcta caggaacaat aggttgtggc attaaaatat
     1861 cctccaatag ttttacttta ctaatagtat acaggaggaa ctccatgaat gatagatacc
     1921 ttgttatgac gcgcttacta tattagaaag ttggctctct aattaaatta attctcatta
     1981 tatatatcaa aagaccgcag tttgaaaact acggtctaat tttttgtcca aatgtaaatc
     2041 acttggaact attattcaat ttattctttt tagtaaatgt tcccgtttta atcccagtta
     2101 cagtttttaa tcctctgtaa ccgttgattt tacaaagctt ttaatttttt tgcgattact
     2161 cccactcaac tgttgcaggt ggtttacttg taatatcgta gacgatacgg ttaacatgat
     2221 ccacttcatt tacgatacgt actgagattt tttgaagtac ttcccatgga attttggcaa
     2281 aatcagcagt cataccatcg atagaagtga tagcacggat tgcaatcgtg tagtcatacg
     2341 tacgaccgtc acccataaca ccgactgaac gaacgcctgt gttaacagtg aagtattgcc
     2401 aaatatcgcg gtcaagtcca gctttagcga tttcttcacg aagaatagcg tctgattcac
     2461 gaacggtttc aagtttctct tcagtgattt cacccatgac acggatagca agtcctggtc
     2521 ctgggaatgg ttggcgccat acgatatggt ctggcatacc aagctctgta ccaagagcac
     2581 gaacttcatc cttgtaaaga gtattgagtg gttcaatcaa ttcaaactgc atatcttctg
     2641 gaagaccacc cacgttgtgg tgtgacttga tagtttgagc tgtatccgta ccagactcga
     2701 taacatctgt atataaagta ccttgagcaa ggaatttcac atctttgagc ttgcttgctt
     2761 cgtcatcgaa tacatagaca aactcgttac caatgatttt acgtttttgt tcaggatcag
     2821 aaacgccagc aagtttgtca aggaaacgtt tagcagcgtc tgctttgacg atattcaaac
     2881 caaacttacc accgagcatg tccataactt gatcagcttc gcctttacga agaagaccgt
     2941 ggtctacgaa gatacagatc aattgatcgc caatcgcttt ttggagaaga accccaacga
     3001 cagatgagtc aacaccacct gatagaccaa gaaggacacg tttatcaccg acggtttcac
     3061 gaattttttt gatctgcatg tcaatgaaat tatccattga ccagtcacct ttagccttac
     3121 aaatgttaag ggcaaagtta cgaaggatat catttccgta tacagaatga cgaacttctg
     3181 ggtggaattg gataccgtaa atgtgtttat ctgggttttc gatggctgcg tatgggcagt
     3241 cagctgatgt acctgtacga acaaagtcag caggaatctc agtaaccgca tcaccatggc
     3301 tcatcaaaac agtctgttca tcaggtgttg attcaaaaag cgctgatggt gtgtgagtta
     3361 gggttgattg accgtattca cgatttccag catcacctgc aggaacaact tttcctccaa
     3421 gtttatgggt caataactgc ataccataac agattcccaa aattggaatt ccgagttcga
     3481 agatttctgg gtcaatatca aatgaaccat cttcatatac agaatttgga ccacctgata
     3541 gaataattcc tacaggattg acttcacgaa cttcagcagc tgaaatttta tggcttttta
     3601 gttctgaaaa aacaccaatc tcacggatac ggcgtgaaat cagctggttg tactggctac
     3661 catagtccaa tacgatgatt ttttctacat cttgcaaatc agttgaaatg ttgctcatct
     3721 ttttcctttc tcaaaagaaa tatcttttct caatattcta tcacaaataa gggcgaatta
     3781 ccaactaaac aaggcgaagt ttgacttttt ctagtttatt ggggtacaat agagaaaaga
     3841 tagaaatgaa gtgaaaaata tgctacctgc ttatatgaaa atccatgatc agataaaaaa
     3901 ggatattgac gagcaccgtt gggctattgg tgagaggctt cccagtgaaa gagatttagc
     3961 tgagcagttt gcggtcagtc gcatgaccct ccgccaagcc gtatctctat tagtcgaaga
     4021 aggcgtctta gagcgccgtg taggaagcgg cacctttgtt tccagtactc gagtacaaga
     4081 aaagatgcga gggacaacca gttttactga aattgtcaaa tcccaaggta aagttccctc
     4141 tagccagctc atttcctaca aaaaaaccat tcccaatgag caagaagttg ccaagctagg
     4201 aatttttcca acggacaata ttatccgaat ggagcgggtc cgctatgccg accaagttcc
     4261 cctagtttat gaagttgctt ctattcctga aaaattcatt aaggacttta aaaaagaaga
     4321 aatcaccagt catttcttcc aaaccttgca aaaacatggc tatcgtatcg gtaaatccca
     4381 acagaccatc tatgctcgcc ttgctaaaga aaagattgcc cactatttgg aagttgaaaa
     4441 aggacatgct attcttggat tgacccagat ttcctaccta gaagatggta ctgcttttga
     4501 atacgtaaaa agtcaatatg taggcgaacg ctttgaattt tatcttgaaa ataattagat
     4561 taccacgcaa aaactctctg tcacggacaa agagtctttt ttatttttct aagaataaat
     4621 ctttcaaaga aatcaaagtt acagcaaaca atatcattgc cataccaaga aaatcaatgg
     4681 gataaaattg ttcattcatt attaagaagg caaagaaaat cgccgatatt ggctcaattg
     4741 aagccaacaa gcttgacttg accggtccta tcagactggc tcctttaagg aaagctgtat
     4801 aggcaaagac agtcccgata aggataatgc ctgcaaacgc aaggagaaaa tcaagactag
     4861 tcgggatatc ggcctgtaga acccctgtaa aaggaagggc gaccaaacct gctatgacca
     4921 ttcccacacc aatgaccaag ctgctccccc actttttaat caaggctatg tgtaaaatga
     4981 tatacaaagc ataagtcaag gcagaaaaga gaccccagaa cagaccagca ggtgtcatgg
     5041 ataactggtc caactgccca tgtgttgcga tcaggaaggt tcctccgatg gcgaatatga
     5101 tggaaactat ctctcccagt gtcggtgcca ccctatcctt gatacagcta taaattaaaa
     5161 ttccgacagg acaaacatac tgaagcaccg tcgctgttcc cgcattggtc tcctgaatag
     5221 cagacagata ggcgaattgg ttgagaaaaa gaccaatcag agcaaaaata agaagagaca
     5281 gcaaactctt tctatccttt aaaaagacca gtattttatc ctttgcagta gcataagcca
     5341 agagcatgag aattccacca gcgattaaaa gacgcaagtt agtcaagacc agagccgaaa
     5401 ttccgtgtgc cattaggtat tggccactcg ttcctgacaa cccccaagca ataccagcca
     5461 caactgttag taaagtccct tttaaactat ttgacatgtc tctccttact cttctttgcg
     5521 aatcaagttc atcacttgat tgcggtctaa tatccattga gctctctcgt ccttttcata
     5581 ggtacgattc gataggaaaa tagtggcttc ttgcttctga cgattccaca tgataaaggt
     5641 acctgtatag cccgtatggt ctagccaatc tccttccaaa ttccatgcta aagaacgttc
     5701 cttgtcatcc aaaggagaaa aattttgatt taagtctctt gcaaaatcat ctgctaaata
     5761 gtgttctaaa aagatttgta aatcctttat agtcgaaaat aaaccagcac tcccagcatg
     5821 tctacccagg aaacgagcct tgggatcatg cactatgcct gcctctacac ctctaactgt
     5881 tggaacagca agctcaactg gcccaaactt agtttccgtc attccccaag gtttccagac
     5941 ttgatccttt aaaatcacat ccaaatcttg attaaaaatt ctttccaaaa taaagcccaa
     6001 cagcaaaaaa tggacatccg aataaagaaa ggctggctga cttcgtctgt tgagatgaaa
     6061 catcgcttcc tttaattcag gggctgttaa aagatcacga ttaggaataa aaggatcaag
     6121 gtctgttgca tgagtcaaga gctggcgaat agtgatgtct ggataatcac tctcaggtaa
     6181 aaaatctatt accagtctat caatatctaa ttgacctatt tcccacaaga aggtacaaac
     6241 tgtgccaacc ccaacaacct tgctgacact agctaggtca taaactagtc ctgcctcagt
     6301 ctgcaagcca tgctctgggg cactctggcc taaatagaac tctgtccatt gattgtcctt
     6361 aaaatacgca aaagaggctc cgggataaat tcctgcctcg atttgttctt ctattttttt
     6421 aataatcttg gtccacttca tacttcttca aaccacaatt caacattatt tctatcttta
     6481 ccaaggaaga atttttcaga cttaggaata aaatattcag tagactcaaa cttctggcga
     6541 agacttgcta tgtctaattc attgaccaag aacttgagca tagataagtc ccaggtaacc
     6601 gtattgtcca cagtcaaatc ctgcccctga gctggaataa aatcaaggga tgccccaatt
     6661 tcagatgatt ccaagaaact ttcgatatca gttgggagat gtaattccat agaaatctca
     6721 aatttactta aagaaattga tgccaaatct gtttgaaatt caggcttttc tcctacttct
     6781 actagacttg ctctgtcatc ttccgcatga atcaaaatca aatcatcttc tggtgagaaa
     6841 atttcaaaag cgtagccatt ttgaccttta tataatcgat gaatcgaatc tgttttagat
     6901 aagattcctt caatttctaa gggattttcc accttgacaa tcaatctagc tagttttttt
     6961 cttccctcta ccttacgagt acgcatactg ggagcttctt ctaaaaccag cttttcaaga
     7021 cccgtttggt cacctagtga cagaaaggcc gattcttcta acagggcctt cattccaagg
     7081 gtttcaatat aaaatgtttc atttaatttt ctattattag cttttaaagt aggaataatc
     7141 cgtacaatct gatttacatt cataaattcc tccgtcactt tttattttaa aggattttag
     7201 aattttttac aagatattat gctcaaattt aacattattt agctatttag taaagatagt
     7261 ctttcaaggc ttttgacaaa gcctgataac cagcaatact gaggtgcagt ccatcagttg
     7321 tatattcttt tttgagttgg cctgcttggt ctgtcaaaca atcaaatact ggcacaaatt
     7381 ccacctgcat ataggcagat gcaagctctt gataggcttg attccaattc tgaatttttt
     7441 cattcgagcg gatatagact gcctgctggt acttctctcc ctcattgaca ggcaaaatgg
     7501 aaagcaattt aatctctgtc aatggataat cgcgagcaac ggattgaatg atagcttcga
     7561 gattattgag agcctcattc acaggaacat cctttccgat atcatttgtc ccaatcagaa
     7621 gaaaaatttt atctactgct ccaccatata gatgagcatc aaggttctct agtaacagtc
     7681 ctgtctgata gccacgaatt cctcgattga caatcgtctt tgaagtccca aatagctcct
     7741 gtagaggata atactcgaca atggaatccc caataaaaag aatgtttggt tctacaacag
     7801 aaatgtgatt taggtgacga tatttggttt gaattttttc ttgttccttt aggagccaat
     7861 tttctaataa ctgtactgcc acttcattct cctttttcta accagttttc caagacttga
     7921 taaactcctc cttggctgtt ggctggtgct agagcagtcg ccacagcttt ggctttctca
     7981 tcagcatttt ccatcgcata ggcaattcca gccatttcaa gcatttcaac atcattttca
     8041 ctatcaccaa aagccatgat ttcttgggat ttcaagtccc agcgcttgag taattcctcc
     8101 aagccccatg ctttatgaat cccagcttgg aggatatcaa tgcaaccata gccactggat
     8161 acagctcgga cacggccatc aaagagagca ttgatttctt ccaaaaccga actcaaacgt
     8221 tcctcaccaa caaccatgct catcttgagc acaccaccaa agaggtcaga tgttaattca
     8281 tccacaaatt gcatccgttg gtagaatttt tcaatcattt ctggagtcat aaaactttca
     8341 agatctgtaa aaatcgtacc ttccttgaca aaatcaccct tcatccccgt tacaacaaac
     8401 tggtcctgac acgctcgacc cttgaaatga gccaaagcct tgttgacaat ggcgtcatcc
     8461 catgtctgag cctgaatcaa ttcattgttt tcaaaaatac gagcgccatt agcaacaacc
     8521 agaaccactc gatccaccaa gggactcagt agttgtctca tgcggtgaat ttcattgccc
     8581 gtcgcaatga caaaacgaat gcccctttga tccaactgat ctaaaatctt ttccaatcgt
     8641 gggagatcaa gctgacctct agcatccagc aaggtcccat ccatatctgt cgcaattacc
     8701 ttaatcatca tttactttcc tctggattca agctaatacc acttcaatcc cacatgttca
     8761 ttcatttctt tataggctgt atcaattcgt tccttagtcg cttcatctaa ctggtcacga
     8821 tgactgccat cctctataaa atcttccaaa atataagttt ggtaatgata caagggatat
     8881 ccttctggtg aaaaggttcc ctttggtgtt cgattgaccc aagtaggatg agctttagct
     8941 gttccgatag ttgtttttcc atccttcttc ttgatggtga catccatgag aacaccacgt
     9001 tcagtccact tagcattctc ttcatctccc atagattcaa tccgttgatt ggaaatgaag
     9061 ttccccattt aatagataat gagtttctta tctccatctt tttcaaccgt ttcagatggt
     9121 tcaacaacgt gaggatgccc tccaaagata atatccgctc cccaatcgat catcttgtga
     9181 taaagagctt tttgttcttc agttagttcc aatcgatact caacacccat ctgaagcatg
     9241 ataatggtga tatctgcttc cttctctgcc cgttcaattt caaccttcat cttatcttcg
     9301 tttaaatctg aaagataacg attatagtct tcctgagaaa tatactgctc aattccattg
     9361 aaaccatagg aataggctaa caatgcaacc ttgataccat tcacttcctt aatgaccagc
     9421 ggagcctgat cacgtggttc gtgcgtataa actccgattg gagtgattcc agctttctca
     9481 ataatatcgg ccgttgaaat aactccctca atttgcgaat ccaaaatatg attatgagct
     9541 aaatccagca catgataacc tgcctcctta atagcatcca taacttcagc aggagcatta
     9601 aagagaagat aacccgctaa ataatgatcc ttattaatgg ttccttcaaa atcaccaata
     9661 gctaaatctg ctgcttagtc cccttgcttg agccaaggag tcacatactc aaaattttca
     9721 tgaaagtcat aggtaccgtc ttctttttta gctgaaaaga aaagtccatc gtggtagagc
     9781 aaatccccgt gggccataat tctggcagtt ttttcctctt cctactcctg agacttttgc
     9841 ttagtcccct cttgagaaat agtatctcgt ttttgactag tcaagggatt ccttggaagc
     9901 tttcaaacaa caagaccaag cccattgata aatcaactgc tagcaagagt atcgccacaa
     9961 atcccttatt gctccacttg cgataactcc taaaaagttt accaagccct tcataaaacg
    10021 aaaagctaaa ccaccctgat ttcgattttg tcttctttgt atcttcattc tccctacttt
    10081 cttatgcaag ccttttcttt ttattatatc acagataagt atttctttca caattgaatt
    10141 gaacttccca tctattttct ataaatccta aatgccataa tgctttcaat tcttgtcatt
    10201 ttgtgatatc atgtagagga aatgaactaa tccacagtgg cttattccaa gtataccact
    10261 tgggctttgg cagtagctaa ctgcactaaa cataatataa ggagagaaaa tgtctgcaat
    10321 agaacgtatt acaaaagctg ctcacttaat tgatatgaac gatattatcc gtgaagggaa
    10381 tcctactcta cgcgcgattg ctgaggaagt cactttcccc ctatctgacc aggaaatcat
    10441 cctaggcgaa aagatgatgc aattccttaa acattcccaa gatcctgtca tggctgaaaa
    10501 aatgggactc cgcggtggtg ttggactggc tgctccccag ttagatatct caaaacgcat
    10561 tatcgctgtt ttggtaccta atattgttga agaaggcgaa actccacagg aagcctacga
    10621 tttggaagcc attatgtaca atccaaaaat cgtctctcac tctgttcaag atgctgctct
    10681 tggcgaagga gaaggttgcc tgtctgttga ccgtaacgtg cctggctatg ttgttcgcca
    10741 tgcccgcgtt actgttgact actttgacaa agatggagaa aaacaccgta tcaaactcaa
    10801 aggctacaac tccattgttg ttcagcatga aattgaccac attaacggta tcatgtttta
    10861 cgatcgcatc aatgaaaaag acccatttgc agttaaagat ggtttactga ttcttgaata
    10921 aagaaaatcc cgttgcaaga cggggttttg tgttataata gaggcatgaa aacaaatgat
    10981 attgtctatg gcgtccacgc cgttaccgaa gccctccttg caaatacagg aaacaaactc
    11041 tacctccaag aagatctccg aggtaagaat gttgagaaag tcaaggaact agctacagaa
    11101 aagaaggtgt ccatttcttg gacatcaaaa aaatctctct ctgagatgac tgaaggtgct
    11161 gttcatcaag gttttgttct acgagtgtct gaatttgcct atagcgagct agattacatc
    11221 cttgcaaaaa cacgccaaga agaaaatcca cttctattga ttctagatgg tctaaccgat
    11281 ccccataatc tgggttctat cttgcgaaca gccgatgcga ccaatgtttc aggtgtcatc
    11341 attcccaagc accgtgctgt cggagtaact cctgtcgttg ccaaaacagc cacaggtgct
    11401 attgaacacg ttccaattgc ccgagtgacc aacctcagtc aaaccttaga taaactcaag
    11461 gatgaaggct tctggacctt tggaacggat atgaacggta ctccttgcca caagtggaat
    11521 acaaaaggga aaatcgccct catcatcgga aatgaaggaa aaggcatctc tagcaacatc
    11581 aaaaaacagg tcgatgaaat gattaccatt ccgatgaatg gacatgttca aagcctcaat
    11641 gccagtgttg ctgcagccat tctcatgtac gaagtttttc taaatagact ataaaaaagt
    11701 ttccagtcat ctgattggaa acttttttat gattaactat gttctgtgat aaacttgtag
    11761 gcttcttgac cagcgatagc tccatctcca actgctgttg ttacttggcg aaggtctttc
    11821 aagcgaacat ctccaactgc aaagataccg tcgactgcag tcttcatgtg gctatctgtc
    11881 acaatccagc ctgcctgatc ttggatattc aattctttaa caaaatcgct aagagggtcc
    11941 aaaccaacat agataaagac accaccgaag gcttgctctg tcacttgacc tgttttcaca
    12001 ttttcaaaaa cgacagattc tactctgttt tcacccttga tttccttcac tacagaatcc
    12061 cagataaagc tgattttttc attcgcaaag gcgcgatctt gtaaaacctt ttgggcacga
    12121 agttggtcac gacggtgaac aatggtaaca gtcttagcaa aacgagtcaa gaagagggct
    12181 tcttcaacag ctgaatctcc accaccaact accaataaat cttggtcacg gaagaaagca
    12241 ccatcacaca cagcacagta agaaacacca cgactgttca gttcttcttc tccaggcact
    12301 cccaaaggac ggtgtttaga accagttgct acgataactg tacgtgtttc atatgtttgg
    12361 tcatcagtca tcactttctt aaaatcacca tggtcttcga cattttcaac ataaccataa
    12421 atgtgctcaa caccaagatt ttcaagtggt tcaaacatct tttcagccaa ttcaggtcca
    12481 ctaatattag catatcctgg gtaattttcg atatcagatg tattattcat ctgaccacct
    12541 ggcagaccac cttcaatcaa agctactttt agattgcttc gagcagcata caaggccgca
    12601 gtcatccctg caggtccagc accgataata atagtatcgt acatatagat tccttctttc
    12661 ttgttgtaac tatctttatt ctaactcttt cttgtcaatc acgcaaggat tatgccttga
    12721 aaacaagaat taaactcata accgcaaagg ataatactgg gacaaccaag actccaatca
    12781 taatcatatc atagagatgg gcttggcgag ccccggctgt cttatcaact cccgacatgg
    12841 ctctcagacc aatccaaatc cctaaaaaaa tcagaacaag gatggtggtc aagatcaaac
    12901 tctcgaaata taaagaaaat agttgcagta gcatgatttc tctcatttct atctttttta
    12961 aagagtaaac tcagctagtc caactaactg agttttcctt tatctattat atcaaatata
    13021 agtccgtttg taactagcaa agaattcttt tgtccgctct tctttagggg tgtggataat
    13081 ctcatccgga gttccagact cgatgatttt ccccttatct aagaagagaa ttttatccgc
    13141 aacttgggct acaaaggaca tgtcatgact gaccaaaatc atggtctgac ctgacttagc
    13201 agcatctgca atagactttt ctacttcacc gaccaattct gggtcaaggg ctgaagttgg
    13261 ttcgtctaag agcaaaacat ctggtttcat agcaagcgca cgcgctaggg caacccgttg
    13321 cttctgtcca cctgataaat ggcgaggata atggttttca cggtccgaaa gcccaacctt
    13381 agccaactct tccttggcaa tcttagtcgc ttcttggtca gataatttct tgacaacaac
    13441 caagccttct ttcacattat caagtgctgt tcggcgttca aataaattaa actgttggaa
    13501 aaccatagac aacttacggc gtagggcaag gatttcttct tgagtgattt tagaaaaatc
    13561 aactgaaaaa ccatcaatct gaatagagcc actgtcaggt gtttcaagat aattgagact
    13621 gcgaagaaag gttgattttc cagctcctga agaaccaatc aaggctacaa cttccccttt
    13681 ttgaatatcc aagttcagat gatccaagac agtctgtcct gaaaaggatt tgcttaaatt
    13741 cgaaatctta atcattaacg aaggtctcct ttcacatctg tttgcactgt atcaggtgca
    13801 gaaatagcca tttttctctc gatgaaacga ccgaggcttt caattccgat attgactacc
    13861 caataaacaa gggcaacgga gatgaagcgt tcaaaatagc gataatcagc tccacctaga
    13921 atctgagctt gggcaaagac ttccacaaca cccgcactaa aagctagaga tgttcccttg
    13981 gtcaaaccga tgagggaatt aatcaaggtt ggagtagcta ccaccgctgc attaggaata
    14041 atcactcgtc gataaacttg cgctcgggtc atacccagac tgcgcgccgc ctcaatctca
    14101 ccaggattaa ctgagagaat ggctgcacga atggtttcac tagcataagc tgcctcatta
    14161 aaggcaaaag cgacaatcgc aaaagctgca gctggaatcg cattgatatt gagaccagtt
    14221 ccccattgct gattgagggc tttcaaagcc aaagggattc cgtagtaggt caacatgagt
    14281 tgcaccaaaa tcggtgtccc ttttaagaaa ctaacaaaga aggcctgcaa gggatataaa
    14341 atcttgacac gattgatctt cacaatggca aaaagaagcg ccaaaaccaa gccaaaaagg
    14401 gcaccaccaa ttgtcaacat aattgttgtt ggaagttgtt ggacaattct agggattcca
    14461 tcaaagaccg aacgtaggct aaacagcttg ccatccggaa tcaattgcat caagttttgg
    14521 taccaatctg atgctaaaat cgttgtaaca ttcataaaaa catcctcttc tgataatgat
    14581 tcattctacc atgcttctgc cgtcaatgaa attatttgct acggtcagat acagactttg
    14641 tctacctact agtttatcat actttgaaac agggaagtta tatattttat ctatcaaaga
    14701 gatagataaa aactatttca gtcccagttc ttcataagat tttcgataac cgatttgctt
    14761 aacagttcca ttttctacta aaatgggccg ttttaacaac ataccgtcac ttgctagcaa
    14821 ctcagccgct tcttggtttg acaaacttcc taccttatct tttagcccta attcacggta
    14881 tttgatacca ctggtgttga aaaattgctt caattcaaat cctgaggttt ctagccaatt
    14941 caaaatgact tcttggctag gtgtttcttc cacgatatgg acggctttat aatccacact
    15001 taattgattt aattcttgtt ttgctttttt acaagttgaa catttggggt attcgataaa
    15061 ttctaacatg tgcttctcct tctatttgtt tatatcttta aaatctacgc cttcatgctc
    15121 caagagccaa gctttctttt ccactcctgc agcatagcct gtcagacgct tgcctgctcc
    15181 caacacacga tgacaaggta ctaggataga ccaaggattg cgtcccactg ctccaccaat
    15241 tgcttgagca gaagccactt gcaggtcttg agcaatttgt ccataggtca ctgtctgacc
    15301 ataaggaatg ccctgtaaat agtcccaaac tctcttttca aaattcgttc cgattggcgc
    15361 caagagcaag ttggataaat cctgaggctt gcctttaaag taatcatcta agcaagcaat
    15421 aactgggtct aaaataggat gactaacaac ttcttctatc gtttcatctc ctagtcccct
    15481 ctcaaaatgc ttctgctcct gaacccaaat tccatacaaa taatggtcat cagctacaag
    15541 tgatagaata ccaattggtg aggagtagag tatttttaca tacttctttt gcattatttc
    15601 tttaattttt gataggccaa gcgttcgcca tctactggca ccttaccaac ttgtttaaaa
    15661 ccaagttttt caaaaatatg ttgcataacc ttgttttcag catgcgtatc tgagcgaaaa
    15721 tcaagataat caaaaccttc aatcaagccc tctaagaagg tttgagcaac tccttttccc
    15781 tgcacatctg ctgccacagc aatacggtga aagactagat actctgactc tccagcttgc
    15841 cagtttccct cataaatagc ttcataggcc tcctctggac tcttggtcac agcagcatag
    15901 gctagcagtt ctccctcttc caaggctacg taggcttgcc ctgagatgat atcatcgata
    15961 ataacatctg catttggata gccattttgc cactggtcac taccagcatc tgctaaacat
    16021 tttttggcat cctccatcac ctgcatgatg gcatctactt catttggaaa agctaaacga
    16081 atttccatct tttttcctca tttctgacta gtttctccca tcatagcata atttaagtat
    16141 ttctacaagc agttaaaact tgactttgtg tttttgttat tttataatct agttatcaaa
    16201 actatataaa aaggagttga aaatgaaaac taccttttcc tacccaaaat gggcagaaat
    16261 tccaaacatt gacctctatc tggaccaggt tttgctctat gtcaatcagg tctgcgcccc
    16321 tatctctcct aataaagaca agggcctaac agcatctatg atcaacaatt atgtgaaaaa
    16381 tggttacctg acaaagcctg acaaaaaaaa ataccaacgc caacagattg cccgtttgat
    16441 tgctatcaca accctcaagt ctgtattttc tattcaagaa atagcccaga cacttaatac
    16501 tctacaaact caagcaagtt cagaccaact ctacgatgct tttgtggact acatgaacca
    16561 aggaattgac ccagctaacc ctattatcca aaccagctgc caaaccgtta aactctatca
    16621 tcaaactcta gacttaatcg atcatactca agaggaggta atccaatgaa cactagtctt
    16681 aaactcagca aacaactcag ttttggagag gagattgcta atagcgtgac ccatgctgtg
    16741 ggtgcagtca tcatgcttat cttgctgcct atttcatcca tctatagtta tgaagcacac
    16801 ggatttttat cctctatcgg cgtttccatt ttcgtcatca gtctctttct catgttccta
    16861 tcatccacca tttatcactc tatggcctat ggttcgaccc acaaatatgt tttgcgaatc
    16921 attgaccatt ctatgattta cgttgccatt gccggctcat acacgcccgt tgtcttgacc
    16981 ttgatgaata actggtttgg ctatctgatt attgtcatcc aatggggaac gaccatcttt
    17041 ggtattctct ataaaatctt tgctaaaaat gtcaatgaga aatttagcct tgctctttac
    17101 ctgattatgg gctggttggt tctggctatc attcctgcca ttatcagtca aacgacaccc
    17161 gttttctgga gtctcatggt aactggcgga ctctgttata cagttggagc tggattttat
    17221 gccaagaaaa aaccttattt ccacatgatt tggcatctct ttatcctagc tgcgtccgta
    17281 cttcaataca tcgctattgt ttattacatg taaaaaagtt gagaaattca atctcaactt
    17341 ttttctttac acatattgat aaagtactgg tgcaagcgca catcatcagt caattctgga
    17401 tgaaaagaac ttaccaacat atttttttct tgggctgcaa caatttgatt gttcactgtt
    17461 gctagaattt ctacaccctc accaacacta ctgataatcg gaccacggat aaaggtcatt
    17521 ggaatcttgc caactccctt acattctgct tccgtgtaga aacttcctaa ttggcgccca
    17581 taagcattac gctcgaccac catatccata gttcctagat aactctcttt ctgagaagtg
    17641 atttccttag ccagcaaaat taagcccgca caggtcccaa acactggtaa gccagataga
    17701 atggcttctc ggatgagaag tagcatgttc tggtcacgta agagcttgcc catggttgta
    17761 gactcaccac caggcaaaat caaacccgac aagtcactct gatcttgctg aaaatcatct
    17821 agatttctga gttctacact ctcgacacct aattgatcta gcacttttgc atgttctgca
    17881 aaggcccctt gcaaggccaa tattccgatt ttcatctatt ttcctcgttc agccatgaga
    17941 atttggattt cattttcatt aataccaacc atggcttctc ctaaatcttc agagatttga
    18001 gctaggattt gaggattacg gaagttagtc acagccttaa caatggcact cgctcgttta
    18061 acaggatctc ctgacttgaa aatacctgaa ccgacaaaga ccccctctgc ccctagttgc
    18121 atcattaacg cagcatctgc tggcgttgca acacctccag cagcgaaatt tacaactggc
    18181 aattttccat gttcatgaac atattggacc aattctacag ggacttgcaa atccttggca
    18241 gcaacataaa gctcgtcctc acgtaagttt tgaatgcggc gaatttcctg attcatcata
    18301 cgcatatgac gaacagcttg gacgatatcc cctgtccctg gttctccttt ggtacgaatc
    18361 atggaagcac cttcagcgat acgacgcaag gcttcaccca aatccttagc accacagaca
    18421 aaaggaactt ggaattcttt cttgtccaca tggaaacggt catcagctgg agatagaact
    18481 tcactctcgt cgatataatc aatttcaata gcctctaaaa tctgagcttc aacaaaatgc
    18541 ccgattctga ccttagccat tactggaata ctaaccgctt cttggatttc cttaatcatc
    18601 tttgggtcgc tcatgcggga aactcctcca gctgcacgaa tatcagccgg aattcgttcc
    18661 aaggccatca cagctgccgc accagcagct tctgcgatac gagcctgttc aggattctgc
    18721 acatccataa taacaccacc cttgagcatc tgtgccaagt ttttatttag ttcataacga
    18781 ttttcagtca tttgttttat cctcatcatt tgtattggta gctacctttt cattttaagt
    18841 cagaacagaa tgaagcacaa gataaaaaaa ctataattgt atggggacaa attagctaaa
    18901 aactatctga ccttaactta aggccagata gctcattcat ttttattttt cagccgtaag
    18961 ggcagccatt gtgatgtagt tgtatggttt gttgaagtgt ggcaagaaga agaggtctgt
    19021 caatgccaat ttatcaattg tcacatgctc ttggatagca agtgagaaca tgtggattcc
    19081 catgctaatt gcaatatcat gtgaaaccat ttgggcacca agaatttcac ggctatcttt
    19141 gtcaaagaca atcttaattg ctacttcatg gttgtcatgt ttcatgaatt ctggtttttg
    19201 aagatcgtta aagcctgttt cagttgcgtt gtaaccagca gctttcgctt tttcaagagt
    19261 caaaccagtt gaaaccatgt gaagaccgta gattgagata ccatttgaac cttgaacacc
    19321 gattccttcc aattcatgtc cacaagcatt gtaggcacca acgataccag tgcgaacagc
    19381 atttgaagca agagcgatat agcttgtatc tttacgagca ttgtcataaa cagtcgcaca
    19441 gtcaccaaca gcgtaaacgc ctgggataga tgtttcttgt ttcttgtcta caaggaaggc
    19501 accgttgcgg aagagttcga tcttaccatc tgcaagggct gtgtttggac ggaaaccaac
    19561 tgcaaggata accatatcca cgtcaaagct ttctttgtca gtaatcaagc gttcaacttt
    19621 accgtcacct tcgattgctt taacagtttg acctagagcc aagcggatgt tgtgatcttc
    19681 caagttcttc gccatcattt gtgtgaagtc tttgtcatag taaccgttca agacagtatc
    19741 aacgatatca acaaggacaa cttcttttcc aagacgttca aaggcttcag caagttcaac
    19801 accgatgtaa ccaccaccaa caacggcgat acggtcgagg tgttggctct tgtcagaaag
    19861 tttattgata acttcttcag cattttggta caatttcacg aattgtacgt tttcaagagt
    19921 tgctttaaat tcgcggtttc ctttaacaat ttcaacacct tcgattggtg gcaagattgg
    19981 tgtagaacct gtagcgaaaa tcaatttttc gtatgattct ttgtgctctt ttccttcaac
    20041 ttccgctgta actactttgt tatcatagtc gattgaaaga acaggtgagt tcatgtaaac
    20101 tttagcacct ttagcttcca atttttcttt atcagaatag aacaagcctt cagcaccgtc
    20161 aatttgttca ccaatccaaa gagccattcc acatcctagg aaagagatgt tagagttttg
    20221 gtcaaataca acaatttcgt tctcatttcc aaaattatcc aacatggtat tgatacatgc
    20281 tgtaccagcg tggttagcac cgactacaac gattttactc ataaaaattt cctgccttca
    20341 ttctaaattt accttactag tataccattt accgttagcg tttacaaggg gggtactatt
    20401 atttcagcat tttttatcaa aaataattcc ccatttatcc tgttttcaag cctcatgaat
    20461 tttatgagca tatttcttga ctttttccaa attttgtttg tgaaaattct aactttatgg
    20521 tattataata acatgaaaat gaaatgtaag ggcttcaatt tagatgatta tttgatatta
    20581 caacttattt tctataagag aaaggagttg gtagcttgac tcttcgttca cattctgaac
    20641 ggctaatggg gactactatc actatttcat tagtggatga gcaagccgat atctttctcc
    20701 aaaaatcctt tgacttgctc aaagagcttg aataccgctt caacgccaat agtcaagaat
    20761 ctgagttgat ggaaatcaat tatcaagcag gaatatcccc cgtcacggtt catccagacc
    20821 tgtttgagct gatttcactt gggttagagc atagcctagc gctctctagc cacctcaata
    20881 tcagcattgg tcccttaatt caaacctggc gtatcggttt ttcagatgcc aaggtcgccc
    20941 agcctcaaga aattgaatcg gtgctgcctc taatcaatcc tcatggtatc gagttagatt
    21001 cttctacttc tactgtgttt ttaaaacaga aaggaatgaa gatcgatcta ggttgtttag
    21061 ccaaaggata cagtgcggat aaggttgccc aatttcttag gaaagagggg gtgacttctg
    21121 ccttgatcaa tctgggaggg aatatcctga ccattggaaa aaatcaggca agaggggata
    21181 acccatggca aatcgggatt caagacccag ccaatccgag gggaaatcat ttaatgacca
    21241 tccctgttgt caataaatct gtcgtgactt caggcattta tgaacgtcac ctgaccgtcg
    21301 atggacaaga ttaccatcac atttttgaca gtcaaacagg atatcctgtt gaaacggaac
    21361 tagcgagtct aacaatcatc tctgataaat cagtcgatgg cgaaatctgg acgactcgac
    21421 tctttggaga aagacctgct tctatcttct ggcaagtcga aagtttggag ggcatcgaag
    21481 tcatcctcat cgataaagaa ggccacctaa gctgttcttc aggaattcct actctataga
    21541 gacaactgtt tcaatggaat tttaaaattg tattatgtaa aaagagaaag gaaatctcat
    21601 gttaaaactt attgctattg ttggaacaaa ttcaaaacgt tctacaaacc gtcaattgct
    21661 tcaatacatg caaaaacact ttgctgacaa agctgaaatt gagcttgttg aaatcaaggc
    21721 cattcctgtc ttcaacaaac cagctgacaa gcaagtacct gctgaaatat tggaaattgc
    21781 tgctaaaatc gaagaggcag atggcgttat tatcggtact cctgagtatg atcactctat
    21841 tccagctgtt ttgatgagcg ctcttgcttg gttgtcttat ggtatttacc cacttttgaa
    21901 caaaccaatc atgattacag gtgcttctta cggtacgctt ggttcatctc gtgcccaatt
    21961 gcaacttcgt caaatcttga atgctcctga aatcaaggca aatgttcttc cagatgaatt
    22021 cttgctctca cactctcttc aagcatttaa cccaagtggc gacttggttg accttgatgt
    22081 tatcaagaaa ttggatgcca tctttgatga cttccgtatc tttgtaaaaa tcacagaaaa
    22141 attacgtaat gcacaagaat tacttcgcaa agatgctgaa gactttgact gggaaaattt
    22201 gtaagatagg agaccaaaaa gaatgaaatt tgttggactt gttggatcaa actacgatca
    22261 atcatataac cgtaagctct tggaatttat ccgtcgctac ttcaaactca aatttgaatt
    22321 agaagttctt gaaattgacg aagttccaat gtttaaccaa gatgaaaaat gggatgaaag
    22381 tttccaatta cgttatttat ataacaaaat tactcgtgca gatggtgtta tcattgctac
    22441 tcctgagcat aaccacacta tctcagcttc actcaaatct gtacttgaat ggctttcata
    22501 cgaagttcat ccatttgaaa acaagcctgt tatgattgtg ggtgcatcat actatgacca
    22561 aggaacatca cgtgctcaag ttcaccttcg taaaatcctt gatgctccag gtgttaatgc
    22621 ctacacgctt ccaggtaacg aattccttct tggtaaagct aaggaagctt ttgataacaa
    22681 cggaaatatc accaacgaag gcactgttaa attccttgaa acttgcttag ataactttgt
    22741 taaatacgta ggagtcgttt cgaaattgaa aaaaccaaaa ccaatcgaat cagaagactt
    22801 ggattgtgga aaaccaatcg ctacaaccat cacagaagtt gaccctgacg atccagaatg
    22861 ggtagaaaaa gttgcagcaa tcactggtgc tgtttctggt gatacctatg tcaaattgga
    22921 ccacggtatc ctaacagtta accaaattga tatgttcttg aaagctatgc catttgaatt
    22981 gacatacgct gacgacaaca accaattcct ctactacaac aacgctcacc aagatccaga
    23041 cactatgttc gctaaacgtg taccacctca atcaggtagc cgtatgtcga ctgttcatgg
    23101 ttctcttcca ccagcacgta tgaagaacgt agagtgggtt atcggaacac ttcgcaacgg
    23161 aaaccaagaa tacgtccgta cgatcgttcc aggttctcct gcaggtgtta tcaacactca
    23221 caactaccaa gcaatgtact atcctgatgg atcatacgct ggtatcaatg aaatcgtctt
    23281 taacttccaa ccatggcttg actggtacct aaaagagact ggtcaacgtt tggtgggtgg
    23341 tagcggacca tttgctcctg ctgccggagg tcatggagac gccgatgcta cttctggcgc
    23401 ttctgattca ggggatgctg gaggccacgg tggtgacgca gacgctacag ccggtgcaag
    23461 ttactaatga tagtttttag gaaccattat ggttcctttt tagcgaaaaa agactagcaa
    23521 acacaaactg ctagtctctt tgttatcgtt tcatctatct ttgttaaaag aaagaataca
    23581 tattatgaat ttggatcatc aagactacgg ccatgtaatc ctttttcacg ttgtacttgg
    23641 cgtagttttt ctggtgtaac atcgtttcct tcttcgtcca caattttgat tccttcaatg
    23701 tggtgacgaa cagcgcggcg ataaccttcg atgtactcct cacgtagttt ggcttgttcc
    23761 actttttctt ctggtgttaa gccttctgtt tttttctttt tagcaagctc attgatacga
    23821 gcaatttttt tcggatccat ttcttctcct ctgtaataag ataaagtccg tttatcaaat
    23881 tttatttagt gttaatttgg ttaaaacaag caaacttagc tgctttcttg gttagttgtg
    23941 acaagattgc caaacgattt tgacggacag cctgatcttc agccattacc atagtatttt
    24001 caaagaaagc atcaatgact gggctaagcg caaagagttg tttcaattgc tgacttgcag
    24061 gtcctgataa aacgagtgtt tctactgctt ctgccaaagc tttttcttgg tcattctcaa
    24121 atagtgctga atcaactgta gcaacccctt ctgccttctc agccaggtta aaggcacgag
    24181 aaagtgattc aacagatggt ttaaaatctt cttccttgct tacttctacg agagcacttg
    24241 ctgcttccaa catatctgcc acaacaaagt ttgaacctgc aagaactgct tccttgatat
    24301 cttttggagt agagcccatc atcttatcaa cacgagcctt gataaagtcc ataacctctg
    24361 ctttattttc ataagtcaaa ctgtcaaatt tcaatgcata aaggctatca atcagctcat
    24421 ccatagcaat gtgccaacca aaggcatcca agatacgaac cacaccttga gttgcacgac
    24481 gaagggcata agggtcatta gaacctgatg gaatcaatcc tactgagaag aaactcaaaa
    24541 tcgtatccaa tttgtctgca atggctagaa ctgcaccgac cttgctctct ggaagttctc
    24601 cttcagctga tgtaggcatg tagtgttcac gaatagcagc tgccaccgct ggagtttcac
    24661 cagcaagaag ggtgtatttt tcacccataa ttccttggag ttcgtcaaat tcaccaacca
    24721 tacctgtcaa caagtcaaac ttgtaaatgg ctgctgcacg agcaaggtca actgtttcat
    24781 ccactgacaa accagctttt tctgccaaaa gtacagtgat ttgacccgta cgaatcatgt
    24841 gttcacgaag ggaaccaatc ttctcatgga aggtgacatt gtttaatttt tcaacaagat
    24901 ctgaaatcac caatttttgg tcttcacgcc agaagaattc tccgtcttcc aagcgggcta
    24961 ccaagacttt ttcatttcct ttgatgacat ttttcaaacg ctctgcgttt ccgttacgaa
    25021 cagaaatgaa gtttggcaag agttttccat cttgatcacg aacaacaaag taacgctggt
    25081 gttccttcat agaagtcacc aagacttctt ctggaacttc aaggtattta gcatcaaaac
    25141 ttcccatgaa ggcagttggg tattcaacca aattcaagac ttcattcagc aaatccgcat
    25201 caatttcgat acgtacacca tgttttgcct caattttctt gatttggtca acaatcattt
    25261 gctcacgttc acatggatct gcgattacaa actgcttacg aaggtcttct tcatagctca
    25321 atgctgactg aattttggtt tctttcccca agaaacgatg gccacggctc acacgacctc
    25381 ccttgatatc aaggaaatcc aagtcaaact cttgctcatc caagagaaca gttaaagtgt
    25441 gaacagggcg gatgtattca aagctatttc cagcccagtg catgctgaca gggaaagtca
    25501 atgacttcaa gacatctaca acaccaggaa caatggcttc aactgcttga ccaacttctt
    25561 ccttagtgac atagacatat tcttcaccct tgatttcacg gaattcgata tcttcaacag
    25621 tcaagccttt tccacggaca aatccttgag ctgctttggt gaagtttcca tcactatcca
    25681 aggcaatttc ctttgctggt cccttgaaat cttctgtcaa atcagactgt ttgtctgata
    25741 aaccagtcac acgaacagcc aaacgacgtg gtgttgagaa ggtttgaatg gcttcaaaag
    25801 acaggcggtt ttccttgagg aaggctgcca ttttttcgcc tagttgtttt tcacttggtg
    25861 tgacaacata ggctggtaat tcttcaagac cgagttctac taataagttt tttgtcatgt
    25921 tttttctccg aaaagtatct ttttattttc cagtttgcct tatgtgattg gcacgcaagc
    25981 aaccaacttc gttgtttcat tgctaaaatt ggagccaaaa gtctccaatt ttgcctagta
    26041 tccttagttt cactaaggat accttcatca ctgcggcaac tgactcaggg ctcactctgt
    26101 tcgcccattt tcgtaatttg tcactctctt tattctgcgt cttctgctag gagtttagct
    26161 cttgtttctt catccaaaag tgggtaacct aggcgtttgc gttctgcaac aaaggttttg
    26221 gctacaacac gggccaagtt acggatacga gcgatatagc ctgcacgctc tgttacagat
    26281 acagcaccac gcgcgtcaag cagattaaag gtatgtgaac atttgagaac atagtcatag
    26341 gcagggtgta ccaagccttc ttctaatgca cgaccagctt ctttttcaaa cttatcaaag
    26401 ttttcaagca acatttcttg gtccgaaatt tcaaatgaat attttgagtg ctcatactca
    26461 ggctggataa agatttctcc gtattttaca ccatcagccc actcgatatc atagacagag
    26521 tctacttctt gaatgtaaga agccaagcgc tccaaaccat aggtaacttc cgcagtcaca
    26581 gggccagttg ccaatccacc gacttgttgg aaataagtga actgagtgat ttccattccg
    26641 tcaagccaaa cttcccaacc aagaccagct gaaccagttg atgggttttc ccagttgtcc
    26701 tcaacaaaac gaatatcgtg ctccaaagga ttgattccca atttttccaa agactcaagg
    26761 taaagttctt ggatatttga tggagaaggc ttcatgacca cctggaattg gtggtgttgg
    26821 tagagacggt tagggttttc cccataacga ccgtcagcag gacgacgtga tggctctaca
    26881 taagctgcat tccatggctc aggtccgata gcacgaagga aagtgtaagg actcattgtt
    26941 cccgcacctt tttcattatc ataagcctgc ataagcatac aaccttggtc attccaaaat
    27001 tgttgcaaag taaggatgat ttcctggaaa gtcaatttct tagacattgt ttactccttt
    27061 ttatataaat tacttgcgac atgagtctgc ctcgtcgatc atacgaggca agacgagtta
    27121 gtactgcgtc tagctcaggc actctagtgc tgagcgtggg gcagtccgac tgtaaggagg
    27181 tttctgccac tgatgcagta aaatgttaat ttcttagaca ttgaatactc cttaataaaa
    27241 aatgatttct tgcgacacga gtctgcctcg tcgattatac gaggcaagac gagttagtac
    27301 tgcgtctagc tcagcaccct agtgctgagc gtggggcagt ccgactgtaa ggaggtctct
    27361 gccactgatg cagtgaaatg ttaatttctt agacattgtt tactccttta gtttttatat
    27421 ttctttttca attaatttct gctgaacaaa ccaatctaac aagggaaaag ttttttctgt
    27481 atttgcccat aaatgataag aatctaagac cgcttgtaca ctacctaaat tttctaccaa
    27541 cttatctact gtcaaaaagc ttcgccagta ttcataaaaa atacttgcat agttcttatc
    27601 ataagtcgaa gaaccaaaat cattcaatga atgccaacca tacttcttct gaaaaagttc
    27661 tacgagagat tgattacaaa ttttttccgc ttgaaattcc tcttctgtaa agaaatactt
    27721 gcgactaata tattcaacca tcccctcttc gaaccagata taagagtcat aaccatcaaa
    27781 atcatctaaa aaatgctccg accaatgagc taactcatgt cctacaatct gtaagaggaa
    27841 attttcagat aaagaatgat agtgactttc tattgcttga gtttgctcag aacactcgta
    27901 gtccatcaat tgatacaaat acaactcttt ccaaacagct aaatcaggcg ccataaccat
    27961 tcgtctatta tttgtatagg ctggaacagc gctttcccta ataatctgtg tagcagcatt
    28021 aaaatctgac caaataacgg cttgcggtaa atcacagact gcaagttcat tctttaaaaa
    28081 agattgataa tctttcaact tttcagtatt tcttactaca aaatcacgaa atgtagctag
    28141 ttgactatcg tcttttacaa gataaaggtt gtccacggct ctcctttctt tcacacaata
    28201 gactgaataa gcaaaagaac cgcgtccgac aatcctaggt tgatttaacc taggggcgtc
    28261 agaaacgcgg ttccacccta atttattact tcattgtttt tgaaaatact acagaaagcg
    28321 ccagctcatt attttgccct acttggctcc cactatccca agctcgcttg aagaacgcca
    28381 taagactttc tttcctgctg actattatat caaaaattag aataatgtac aattcttttt
    28441 atgattttct agaaatccac atcatcaact cgtggagcac ccgattgaac agcaatcgtt
    28501 tttaaggttt ctctctcctc atgactcagt tcaattccaa agcaatcaag attagcttga
    28561 atacgagagg ttgtgacaga ttttggaagt ggtaaaaatc cttctgccaa gctccaggcc
    28621 aaggctatct gagcaatcga ttttccgtga tttgctgcga tttcttgcac ttgcttgcta
    28681 tcaaatagtt ctccctgacc aaaaggcccc caagcttcca ataaaattcc cttttcacga
    28741 cagtaagcta cgacttgatc ttgatacaca cctggcgcca agcgaacttg attgaccgca
    28801 ggaacgatag ttgcagtttc aagcaaggca tccaaatgat ggggaagaaa attgctaacg
    28861 ccgatagcac ggattttccc ttcttgatag aggtcttcca tcgctctcca aacttccgca
    28921 ttgcgagttt tccatgcgtc attttctctg agcggttttg ggttcggcca atgaatcaaa
    28981 tacaaatcca aataatccaa gcccagtttt tctatagatt tttccaaagc ttgacgagtt
    29041 tgctcatagg tttgctgact attccaaagc ttggtagtta cgaacatttc ttcacgtgga
    29101 actccgctat ctttgattgc ttgaccaaca ctttcttcat tctgataaat cgccgccgta
    29161 tcaatatgac gataaccagc cttcaaggct tctaacactg catgataggc ttcttctcca
    29221 tccttagcct taaaagttcc aaatcccaat actggaattt ctactccatt atttaattga
    29281 taggtattca tatgcttctc cttctatttt attcatcaat tatagcataa gacatttttt
    29341 aagtagtact atcttctgta aaaaataagt ctgtcaaata tctaacagac ctattttttc
    29401 ttgcttattc atcacgacta tagtacagct catgagcttt taggcgagta ttgagcatct
    29461 ctggtatggt cacaaaggta taaccttgat ttttcaaata ctcaatgacc cttggcaagg
    29521 cattgactgt cggactgtga atatcatgca tcaaaacgat agagccgtta gctacttgat
    29581 gctgaatttc tgtcaaaata gatgcttcat ttttactctt ccagtccaga ctatccacat
    29641 cccacatgat aaagctcaaa tccaagctat tgcgaatatc atctgtaata gcaccataag
    29701 gtggacgcat gagtttagaa ctagaaccca gcactttagt tagcacatcc tcagtatcag
    29761 taatctgctt tttagcttca tcaagagaga gttgcgagag aatcggatgg ctccaactat
    29821 ggtttccaac aacatgacct tcagatttta tcctcttcac caagtcctca ttcccagaaa
    29881 catttttccc aagcacaaag aaagtcgctt taatatcata tttagctagg gtctctaata
    29941 cctgcggggt cgttgctgga tttggaccat catcaaaggt tagagcgaca actttttgat
    30001 atttcttatc aaagtaagat tgatacaagg ccgcatcttt ttcgagtaag tacgaagatt
    30061 ggataacatc aaagaaagca gatactggca aggctatctc ttctaaattt tcaagcacag
    30121 gacttgaata aaggataatc tgactatcct tgtaatcaaa attccatgca gacaagtctt
    30181 ggtcagagaa gctttttaca atctgctcac tctggtcttg ctctattttt ttatcctcta
    30241 tgaaggaggt caactctttt atcagctgtt ccttagcctt actagcatct gaaaacagtt
    30301 ggtcaagtgt aaaaggttgc ccatcttctg ttaagtgaac ctttcctaga ctggtctttt
    30361 cagtctcttc aaccttaaaa gcaactaaat catagatttg tttggtcaca ttacgattaa
    30421 cgactccctt taaacctgac tcttcttgct ctgtatagta gaaaacaaga ttgtccttac
    30481 tttctagctt gtccttaaca tcttgattta tcaactccct aacagaggaa atcactttct
    30541 ccccttggag aggataatag gcaatcactt cggcttgccc ctgacgaaaa tgctccttct
    30601 gatttccctc actcaattga tcatctttct cttttttgag cgattcaatc ttttgctcaa
    30661 aacttttttg ctggtagatc ttaaaagcaa taaatccgcc taataggcaa atagaaattg
    30721 ctaagatacc aatcaaagcc aataatacat gtctcgtttt cccgtgtctg ccacgtccta
    30781 gtctactttt attcatattt atatcataac aaatttgagc aataatttca atgatacaat
    30841 ttggcaatcc acaattcctc tagcaagcca aagcatctta catcaactcc aacatccgta
    30901 tctgtagaga ttatgtagtt ttctatctat ggaatttcta gtaaattgaa gctagaatag
    30961 tagacctata cttctaaaac attgttagaa atcgatttga ttgtcctgat cgatttgtcc
    31021 tgttcttatt tcattttact ataaaactat gaaaagctag gtcatctgag aagtaattac
    31081 tatcgacaat tgcgatagcg tatactggtg cgatttgttt gtagctctgg tgggtatcac
    31141 cttcacgttg gcgaattttt tctaggtttt gattaacctg actgcacaga taagcccata
    31201 ggcgattgat gaaaaaattc tgatgatgaa cctgaatttc gatgataact tgaattccat
    31261 tatctaactc cgccaagacg tctatactag tatagaaatc ctgcgctgag taggacatgg
    31321 aaggcaagac gtgaatgtta cttccctcca aaatcgtcac attttttgct ggcaagtcca
    31381 gcatatcgcg gataaattga caaatcatta gttgggctga tacccggatg tctgagaatc
    31441 ctccttttcc tccttctatt atagcacatt tttaaatcta ggtttgctag attctatgct
    31501 tctatctatt tattcggaaa agaaagcttt tcttcagaag aaagctaata gcttatttga
    31561 aattttctcc tctctgttgg atagtcccgt ctatctatgt tataatgaaa gaaggattta
    31621 aaatcggaaa aggagtattt atgctaaaat taggtgtcat cggaactggc gctatcagcc
    31681 atcatttcat agaagcagcc cataccagtg gagaatacca actggtcgca atctattcta
    31741 gaaaactaga aactgcagca acctttgctt ctcgctatca gaatatccaa ctattcgatc
    31801 aattagaagt cttcttcaaa tcttcttttg atttagtcta tatcgccagt ccaaactcct
    31861 tacattttgc tcaggcaaaa gctgccttgt ctgctggtaa acatgttatt ctcgaaaagc
    31921 cagctgtcac tcaaccacaa gaatggtttg atttgattca aacagctgaa aaaaataact
    31981 gttttatctt tgaagcagct cgtaattacc acgagaaagc ctttactact atcaaaaact
    32041 ttttagcaga taagcaagtg ttaggagcag atttcaacta ttccaaatac tcttccaaga
    32101 tgcctgactt gttggctgga caaacaccaa atgtcttttc agaccgtttt gctggtggag
    32161 ccctcatgga tttggggatt tatcccctct atgctgctgt tcgtcttttt ggaaaagcca
    32221 atgacgcgac ttaccatgct caacagcttg acaatagcat tgacctaaat ggagatggta
    32281 ccctcttcta cccagactat caagttcaca tcaaggctgg aaaaaacatc acttccaatc
    32341 ttccttgcga gatttataca acagatggaa ccttgactct caacacgatt gagcatattc
    32401 gctcagctat ttttaccgac caccaaggaa atcaagtcca gcttcctatc caacaggatc
    32461 ctcatacgat gactgaggaa gtcgctgcat ttgcacacat gatccagcaa ccagatctga
    32521 atctctacca aacttggctg tatgatgcag gctctgttca tgagctacta tataccatgc
    32581 gccagactgc tggcattaga tttgaggcag aaaaatgaaa accaaactac cgactgaatg
    32641 gcaagaactg agtgaccaac tcggtttcca agaattcacc ctcattcaaa ctcaactatt
    32701 tgagcccctt cttgctggag aaaacctcct aggagtgagc caaaccggaa ctggtaagac
    32761 cctagcgtat ctcctaccaa gtcttctcag actacaaaag aaaaaagccc aacaactctt
    32821 gattctagca ccaaatacgg aacttgctgg acagattttt gatgtatgta aaacgtgggc
    32881 agaagctatc ggattgactg ctcaactctt cctttcaggt tcaagtcaga aacgacaaat
    32941 tgaacgcctt aaaaagggat cagaaattct gattggaact cctggccgta tctttgaact
    33001 cattaaactt aaaaaaatca agatgatgaa tgtggaaacc atcatcctgg atgaatttga
    33061 ccaattacta gatgattctc agattcactt tgtagaaaaa atcactcact acgcacctcg
    33121 tgaccaccaa ctggtctaca tgagtgccac gaccaagttt gaccaagaaa agattgtgcc
    33181 gaatacacgc actattgatc tctctgatca aaaattggac aatatccagc atttctacat
    33241 gcaggtagac caacgtcatc gagtggatat gctacgaaaa ctggctcatg tagaggattt
    33301 ccgtggtcta gtcttcttca atagcctgtc agaccttggg aatgccgagg aaaaactaca
    33361 gtatcgtgat atattggctg tttccctcgc tagtgatgtt aatgttaaat ttagaaaaat
    33421 catcttagaa aagtttaaag ataaccaact aaccctgctt cttgcaactg accttttggc
    33481 tcgtggaatt gatatcgata gcctagaatg tgtcgtaaac tttgatattc ctagagatag
    33541 cgaaacctac acacaccgtg ctggccgtac tggtcgtatg ggcaaggaag gttatgttat
    33601 cactctcgtc actcatccag aagaaatcaa aaaacttaaa aagtttgcaa gtatccgaga
    33661 aattgtccta aaaaaccaag aactctatat caaataaagc cctattgctc tatacacatc
    33721 cagtgtatgg agctttttta taagcaattc aattttatac tcatctgctt tcaaaaagca
    33781 ttctagtcca tttccgatta acgatggact ttatcacctc cttctccagt ccttgtatga
    33841 catcttccaa agttcgaaag gctttattct taaatccacg tttacgaatc tctttccaca
    33901 cttgttcaat ggggttcatc tctggtgtgt atggaggaat aaatgcaaag ccaatattag
    33961 tcggaatctt taaggtactt gatttatgcc atatagcatt gtccataacg agtaaaaaat
    34021 aatcatatgg ataagcttgt gaaagctctt ctaaaaagac gttcatccac tcagtattac
    34081 atccaccagc tattaaga
//
LOCUS       DAVHKZ010000022        33412 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000022 DAVHKZ010000000
VERSION     DAVHKZ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33412
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.022"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(120..1100)
                     /locus_tag="VVO74_001249"
     CDS             complement(120..1100)
                     /locus_tag="VVO74_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU5695269.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTPPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1416..3431)
                     /gene="recG"
                     /locus_tag="VVO74_001250"
     CDS             complement(1416..3431)
                     /gene="recG"
                     /locus_tag="VVO74_001250"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU5695270.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLDWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3450..4553)
                     /locus_tag="VVO74_001251"
     CDS             complement(3450..4553)
                     /locus_tag="VVO74_001251"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU5695271.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4543..4911)
                     /locus_tag="VVO74_001252"
     CDS             complement(4543..4911)
                     /locus_tag="VVO74_001252"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU5695272.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(4950..5981)
                     /locus_tag="VVO74_001253"
     CDS             complement(4950..5981)
                     /locus_tag="VVO74_001253"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU5695273.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMELENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEVFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(5983..7014)
                     /locus_tag="VVO74_001254"
     CDS             complement(5983..7014)
                     /locus_tag="VVO74_001254"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU5695274.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7095..9608)
                     /gene="secA"
                     /locus_tag="VVO74_001255"
     CDS             complement(7095..9608)
                     /gene="secA"
                     /locus_tag="VVO74_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU5695275.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(9754..10041)
                     /locus_tag="VVO74_001256"
     CDS             complement(9754..10041)
                     /locus_tag="VVO74_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695276.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLTFFFIPWDRAILGVRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            complement(10052..10702)
                     /locus_tag="VVO74_001257"
     CDS             complement(10052..10702)
                     /locus_tag="VVO74_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU5695277.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGNNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISKDISDLCTDVLAVENGHIQYVKDIQS"
     gene            complement(10706..11347)
                     /locus_tag="VVO74_001258"
     CDS             complement(10706..11347)
                     /locus_tag="VVO74_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695278.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEVNLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            complement(11340..12131)
                     /locus_tag="VVO74_001259"
     CDS             complement(11340..12131)
                     /locus_tag="VVO74_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695279.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAILTHFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAVYFLQIVDYLGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(12316..12651)
                     /locus_tag="VVO74_001260"
     CDS             complement(12316..12651)
                     /locus_tag="VVO74_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695280.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNVADIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(12791..13126)
                     /locus_tag="VVO74_001261"
     CDS             complement(12791..13126)
                     /locus_tag="VVO74_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695281.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13217..14527)
                     /gene="der"
                     /locus_tag="VVO74_001262"
     CDS             complement(13217..14527)
                     /gene="der"
                     /locus_tag="VVO74_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU5695282.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14541..15254)
                     /locus_tag="VVO74_001263"
     CDS             complement(14541..15254)
                     /locus_tag="VVO74_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU5695283.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15251..16147)
                     /gene="dnaI"
                     /locus_tag="VVO74_001264"
     CDS             complement(15251..16147)
                     /gene="dnaI"
                     /locus_tag="VVO74_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU5695284.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16148..17317)
                     /locus_tag="VVO74_001265"
     CDS             complement(16148..17317)
                     /locus_tag="VVO74_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU5695285.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLVLHAPLSSQD
                     FLEHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     EQKAKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            complement(17318..17791)
                     /gene="nrdR"
                     /locus_tag="VVO74_001266"
     CDS             complement(17318..17791)
                     /gene="nrdR"
                     /locus_tag="VVO74_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU5695286.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            17931..18296
                     /locus_tag="VVO74_001267"
     CDS             17931..18296
                     /locus_tag="VVO74_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU5695287.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18301..18996
                     /locus_tag="VVO74_001268"
     CDS             18301..18996
                     /locus_tag="VVO74_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695288.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19013..19780
                     /locus_tag="VVO74_001269"
     CDS             19013..19780
                     /locus_tag="VVO74_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695289.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20133..21332)
                     /locus_tag="VVO74_001270"
     CDS             complement(20133..21332)
                     /locus_tag="VVO74_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5695290.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHIQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21329..22222)
                     /locus_tag="VVO74_001271"
     CDS             complement(21329..22222)
                     /locus_tag="VVO74_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695291.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            22338..22418
                     /locus_tag="VVO74_001272"
                     /pseudo
     CDS             22338..22418
                     /locus_tag="VVO74_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            22903..23116
                     /locus_tag="VVO74_001273"
                     /pseudo
     CDS             22903..23116
                     /locus_tag="VVO74_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            23531..24148
                     /locus_tag="VVO74_001274"
     CDS             23531..24148
                     /locus_tag="VVO74_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU5695292.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(24468..25355)
                     /locus_tag="VVO74_001275"
     CDS             complement(24468..25355)
                     /locus_tag="VVO74_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU5695293.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGENIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(25504..27387)
                     /locus_tag="VVO74_001276"
     CDS             complement(25504..27387)
                     /locus_tag="VVO74_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU5695294.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            27764..29218
                     /locus_tag="VVO74_001277"
     CDS             27764..29218
                     /locus_tag="VVO74_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU5695295.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            29199..30164
                     /locus_tag="VVO74_001278"
     CDS             29199..30164
                     /locus_tag="VVO74_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU5695296.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(30199..31473)
                     /locus_tag="VVO74_001279"
     CDS             complement(30199..31473)
                     /locus_tag="VVO74_001279"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU5695297.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(31473..32645)
                     /locus_tag="VVO74_001280"
     CDS             complement(31473..32645)
                     /locus_tag="VVO74_001280"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU5695298.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(32776..33024)
                     /locus_tag="VVO74_001281"
     CDS             complement(32776..33024)
                     /locus_tag="VVO74_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695299.1"
                     /translation="MVSSWGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(33092..>33412)
                     /locus_tag="VVO74_001282"
     CDS             complement(33092..>33412)
                     /locus_tag="VVO74_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU5695300.1"
                     /translation="HDMKLFKMSRRNIGQAGKILSDSGYQGLMKIYPQVQTPRKSSKL
                     KPLTAEDKACNHALSKERSKVENIFAKVKTFKMFSTIYRNHRKRFGLRMNLIAGIINH
                     ELGF"
BASE COUNT         9771 a         7468 c         6331 g         9842 t
ORIGIN      
        1 cctattcttg tttcatttta ctatatttcc atgataaaac gcatagtatc aagttttttt
       61 aatcccctga tactatgcgt gtttgtaatt tttaagattt tgtgcttaga gtcgactcct
      121 tattttagat atttaaaagg aatctcactt ccacagagcc agttgtagac ttggtcattg
      181 acaaatacat tcatggcttc gtgagcatac tcaggcatga tacgataggt tttatcgcag
      241 gtcagacgat tataaatcgc aaactgggta atgggatagc aaacatcgtc gtccaagccc
      301 gtaatcatct taacctcacc ttggatacga tgggcaagat ttttgacatc gatataggca
      361 agggtcgcca tgatttcctc ctctgtttca tggaaggggt cgtgaaactt gaaataacgg
      421 aaaagttcgt cgtaagcctc gctagtatta ccaatctcaa tcacccgtct gaagtctgac
      481 aagaagggat aaatggcaac tgttttctga attcgaggat tgagcgctgc tgcaactaga
      541 gctagagccc ctccttgtga ggcaccatag ctagaaagac gcttctcatc aacctgagac
      601 agactagcaa caatttcgac caactggtaa atatccagat aaacatcctt ataaaagagg
      661 tggtcccgac cttccatagc accacggata atatgcccct tcacggtatt tcctaaagga
      721 gaacgcaagc cgtcttgtga gtaacctgac tggccccgca catccatgga aacaacacca
      781 taaccagcta cggtgaagcc cagcatgtcg gcccagtccc agccacgtcc catataacca
      841 tgaaaatgga agattagtgg aaccttctcc tcactctttg gaagaacaat gcgtgcatag
      901 acctttcctt ccttgcttcc ttcaaatgtt aactcatagc acttgacttg aggaatgtgg
      961 aaatctcttt cctccaagtg gtaggatgga ggtgtggaaa catttttcac ttccccatcc
     1021 cagaaagcat caaagtcttc cggaacctca tcccttcctc tataggtctt aatttcttct
     1081 agcaaagctg gatttttcat agcatgctcc ttttattttg taatcgttac cacaactgta
     1141 gcatatctat gtaatcaatg caagaaagaa ggataaatag aaagtgaatt tagattcttt
     1201 acttttagga tgatgggctg aaagtagttt tagaaacgaa aaagagcatt tcgctctctc
     1261 ttctgtttat actagttttt tgcttccttc ttttggaaag tggtttggta atttacttta
     1321 atcgttactg tcatatgaga gtcctcgttt ctttttgatg actttagtat aagagccaaa
     1381 cctaaaaact agcttaagtt ttccttagag aaagcttaat ccagatgttc tttcttttcc
     1441 agatgaaggg caatcatgcg ccactctgga tcttcttgcc aagcttctat agaactaatg
     1501 tagctagcaa cctttcttgc ttcttctaaa atcggaaaat cttcgataat atcagccact
     1561 tggaactctg gaagtcctga ctgtctggtt ccaaaaatct caccagaacc acgcattttc
     1621 aaatcttcct ccgcaaggac aaatccattg gtcgtttctg tcatgatgcg catgcggtct
     1681 ttcccagaat ccgtcttggg attggcaacg agaacagcgt aggactgctt gtccccccga
     1741 ccgacacgac ctctaagctg gtgaagttga ctgagaccga agcgatcggc atccatgata
     1801 atcatgacag tcgcattggg aacgttgacc ccaacctcaa taaccgtcgt cgaaaccaga
     1861 atatccgtct ttctctcctt gaaatcctgc atgatctggt ctttttcgtc actcttcatc
     1921 ctaccatgta gaagagccac ctctgccttg cctgcaaaat gagtcgtcaa ctcctctgat
     1981 aaggcaatgg catttttcaa atctagagct tctgattctt caatcaaagg agagatgaca
     2041 taggcttggg aacctttttg aatttccccc tctaaccaag tcaagacctg aggtagttgc
     2101 tcatgtttga tccagcgcgt cacaataggc ttccgacctg ctggcatctg gtcgataatg
     2161 gaaacatcca tatctccaaa ggctgtgatg gcaagcgtcc gtggaatggg agtcgccgtc
     2221 atcatgagga catctggatt gtcacctttt tcccgtaaaa tacgcctttg ccctacacca
     2281 aaacggtgct gctcatcgat aataatcaaa ccaagacgag catactccac cccatcttgt
     2341 atcagagcgt gagttcctat aatcaaatca gcctcaccct tggcaatggt ctccaagact
     2401 tctctctttt ctgcagcttt caaggaacct gtcaagagag ccagtttcaa attgggaaaa
     2461 aggttctgta aactctcaaa gtgttgctct gcgaggattt ctgttggtac cattagggca
     2521 gcctgataac ctgctgtcac tgccgcaaac atggccaagc cagcgactac cgtttttcca
     2581 ctccccacat ctccttgtag gagacgattc atgtggtggt cggacttcat atcagttaaa
     2641 atttcctgca aactcttttc ctgagcttgg gtcagggcaa aaggaagact tgctttaact
     2701 gctgtcactt tttcctgaga ccaatccaga accagaccac ttccctgaac tctattttca
     2761 gacttgagcg tctgcagctg catttggaaa taaaagagtt cctcaaactt gatacggcga
     2821 agagcctgct tgtattctgc caaatccttt ggaaaatgca tagctcggac tgcctgacaa
     2881 cgggacatga gtttgtattt gtctagtaaa gactggggca gattttcttc tatcaagagg
     2941 tccagtccct gatcaaaagc cgtcttgatg accttgacca gactggcctg actgattccc
     3001 tgagccagac gatagacagg ctggaggtca tcttctacct gagccagaac cttcatccca
     3061 gtcagactag ccttagcgcg gtcccatttt ccaaagacag caagggttgc tcccaactct
     3121 attttatcag ccagataggg ctggttaaag aaattcaccg caaaaacgac ctctccctgc
     3181 ttgagactaa aacgcaggcg attgcgcttg aaaccataat actggacact agcaggagtc
     3241 actacctgac cagaaagaac tgccttctca ccgtcttcca gctccagcac ctgcttggtt
     3301 ttgaagtctt cataacggaa aggaaagtag agcaagagat cttgcaagtt ttcaattcct
     3361 agtttggcgt atttttctgc tgactttggt cccacaccag gcaagacatg caagggttga
     3421 tgtagattca tgctccactc ctttcttttc taataatatt ctctcggaat acggtcgctg
     3481 aggaggcaaa ccacctcata gttaatggtt acgcggtagg tcgctacctg agttgcagtg
     3541 atttccttat ccccattgga gccaatcaag gttaccttgg ttcctagcgg ataaagctta
     3601 ggcaatcgaa tagtgatttg gtccatcgaa accctgccga caattgggca agcttggcca
     3661 tctaccaaga cagagaaatt ttgcatgtct cttgtccatc catctgcata cccgattggc
     3721 acggtcgcga tgacttgctc gctatccgct tgataagttg ctccatagcc catgcaagct
     3781 ccagctggaa ctgtcttgac atgaaccaga gcagactcca aggtcaaggc cggtatcaaa
     3841 tcataaggca aatccaagac cgctccactt ggattgaggc catacatggc atctcccata
     3901 cgaaccgcat tgaaaatagt ctctacatgc caaagagtcg ttgcagaatt gctagcatga
     3961 accagctctg gaacttcctt catactagct aaaatagttt taaaccgttc taactgggca
     4021 ttaaaatagt catctgattc ctcatcagca gtagcaaagt gggtaaagat tccttcaaca
     4081 cgaacaccgt gttgttgtag caaatcttga gcctgctcaa cctcactggc ctctctaaaa
     4141 ccaatccgtc ccatccctga atcaatcttg aggtggactg tcaatccagt taggtccact
     4201 tccttatcta agagtgcttg aatccactcc agtccagcca ctgtcaaggt gaagtcatat
     4261 tctttagcta gagcaacagc ttcgatttca gaaactccta aaatgaggat tggcttgctg
     4321 agtccagctt gtctgagttc aatggcttca tcgatattgg aaacgcaaaa gccatcaaca
     4381 tcatcttgaa ttgccttggc aacggcaaca gctccatgac cataagcatt ggccttgacc
     4441 acagccaact tgagcgttcc ttgagggata tgagccccca tttgctgaat attttgtcga
     4501 atagctccca gatgaatcag agccttggtt ggtctatgtg gactagcttt catgattttc
     4561 ctccaaaatg acactggctg tcacaaactg atcggtgtgg ctgatagaca gccaaatctt
     4621 tcctgaaaat ggtgcctgac taaaataagg cgccccacgt tcattgttca agacttccaa
     4681 atcctgaaaa ccgagcttgc taatgcccgt tcccatagcc ttggaaaagg cctccttagc
     4741 cgaccagcga ccagctaaat attctatttg cctgcgtcct ttgagactgg tgaagcgctc
     4801 catttcctga gcggtcagta cacgcttagc aaatccttca tgtcgtgtaa ctgcgctttc
     4861 tatcgaagcc aattcttcga tgtcaattcc gtgtccaact atcattctca tcaaaaggag
     4921 ttgagattcc ccaactccat ccttttcact tattttgtca aggtaacata aatctcttct
     4981 accaaggcct ctgtattttc ccaacctagg caagggtcag taatagagca accaaagacc
     5041 tctggttggt tttgacgacc atctgctagg taagattcaa tcataaatcc tcgaaccgtc
     5101 tttttaattt tctcattcca atcacgattc tgcaaggtct ggcgaacaat tcgaatctgc
     5161 tccatatatt gcttgcctga gttatcatgg ttggtgtcaa tgaggataaa aggattttca
     5221 agttccatgg tttcatagcg ttcaatggct tggagtaggt tttcatagta gtaattcggc
     5281 atataattgc catactcgtt gactgctcca cggaggataa catgggccaa aggattacct
     5341 gatgtctcaa cttcctgccc atgataaagg aaggtttgct tgttttgagc agcatagatg
     5401 gcgttaaaca taacacccaa atttcctgag gttggatttt tcatccctac tggtgcatca
     5461 atcccagaag ccacaaagcg gtgctcttgg tcttccacag aacgagctcc aacggcatgg
     5521 tagctgacca agtcatccac caagatcaga tttgacggat aaagcatctc atctgccgtt
     5581 gtcaaaccag tctctgtaat cacgcggtag tgcaactggc gcacagcctg caagccgtta
     5641 atcaggcttg gagccttaga agtatctggc tggtgaacca atcctttata gccgtctcca
     5701 ttggtacgag gcttagcagt atacacgcgc atgaccatga aaatcttgtc cgctaccttc
     5761 ttttgcaagg cggataaacg gcgagcatat tccaagaccg cctcttcatt atcagaagag
     5821 caaggaccaa tcaccaagag aatacggtca tcttcccctg aaataatatc tgccaattcc
     5881 ctgtcacggc tttccttgag tctcaaggct tccgcagaca attgggtttc agccttgatg
     5941 acttccatat cgatttcttg acctttttca ataaatgcca tcttattctc ctaacgtttt
     6001 gtaaatttct ctgacaagag cttctgtgtt atcccaaccc aggcaagggt ctgtgataga
     6061 cttaccaaat acttctggct cattttgtcg accatcttcc agataagact caatcataaa
     6121 accacgaacg aactgcttaa ttttttcatt ccaagcacgg ttaatcaagg tctggcggac
     6181 aattcggatc tgttcaatat actgcttacc agaattgtca tgattggtat caatgatgat
     6241 aaaaggattt tccaagccca ttttctcata ctgggcaatg gtatcaatta aattgtcata
     6301 atagtagttg ggaatatttt ttccatactc attaagagca ccacgaagaa tagcgtgtga
     6361 aagcgggttc ccagttgttt ctacttcttt tcctaagaaa aggaaacttt gtttgttttg
     6421 agcagcataa atcccattaa acatgacatt gagatttcca gaggttggat ttttaaaacc
     6481 agtagaaaat cctgccccac ttgccacaaa gcggtgttgc tggtcttcaa ctgaacgggc
     6541 accaactgcc atgtaagaaa tcaaatcatc tacaagcgga aggttttcag gataaagcat
     6601 ttcatcagca gttgtcatcc ctgtttctgt gatgacacga tagtgaagat ggcgaacggc
     6661 tttgattcca ttgataagac taggcgcttc tgtcgcgtta ggctggtgaa tcaagccctt
     6721 atagccatct ccgttggtac ggggtttggc agtataaaca cgcataacca taaagatacg
     6781 atctgccact tcttcttgta ggactgccaa acgcttagcg tattcaagga cagcttcttc
     6841 gttgtcagat gagcatggcc cgattaccaa gagaattcgc tggtcttctc cacgtataat
     6901 ggcttctagc tcttgatctc gctgtgattt cctctccaaa gcctgacctt ctaattttga
     6961 caaggcacga acttcttcta tatttatttt agagcttttt gctgtaaata ccataactca
     7021 tctccttata aagcaaacgg atacccagta aaaatttact tttcacaaga tatccgcctc
     7081 taaactatct cattttattg tcttttaccg tgacagtttt taaatttctt accagaacca
     7141 catgggcaaa gttcattgcg tccaatctgg ctcaaatcca aatcttctgg catacttgct
     7201 tggtgagcag cgatattgcg agtcgctgtt gtactgatat gacgttctgc ctgtggtctt
     7261 tcttgttcat gaatttgtgc tttcatcatc aagcgtgtca catcaaactc aatcgaacca
     7321 atcatatcat taaacatacg gaaaccttct gcctgatact caacaacagg gttgttctga
     7381 gcatagccac gaagtccaac cgcgttacgc aattgatcaa gggcatcgat atgatctgtc
     7441 cacttgttat ccaccactcg tagaatcaaa actttttgga attctttaac tgcttcttca
     7501 tcgcgtagtt ttgaaacctg actatcgtaa accttcaagg cacgttggaa aagctcttcc
     7561 ttgatggcct tatcagacaa gcctgacaag tcttccatcg taatagaatc ttcaggaagc
     7621 aagttgtact tagcaaagtt caaaattgcc tctagttttt catcttgttt ggcacgcgca
     7681 tgaccatcaa cgacacgttc aatcgtgcgt ttgatcatag actgaatttc aggtgccaag
     7741 tcacgatctg cagtgatgac atcgtaacgt tgagcataga taatctcacg ttgttcacgc
     7801 atgacatcat cgtattgaag gacttgttta cgggtatcgt agttatttcc ttcgacacgt
     7861 ttctgagctg cttcaacctg acgcgtcaac atgcgagact caatcgcctc ttcagacatg
     7921 ttcaagcgtt caaagattcc cttcaagcgt tcagaaccaa aacgtttcat caaatcatct
     7981 tcaagagata ggtagaattg tgactcacct ggatctcctt gacgacctga acgtccacga
     8041 agctggttat cgatacgacg actttcatga cgttctgtac caataacaca aagtcctcca
     8101 agttcacgaa caccttcacc aagcttgatg tcggtaccac gacccgccat gttggttgcg
     8161 atggtaacgg caccacgttg accagcattc atgatgattt gggcttctct atagtggttt
     8221 ttggcattca agacttcgtg aggaacacca gctgcaacca atttcttaga aatgtagtca
     8281 ctagtttcaa ccgctactgt accaaccaag acaggttgac ccttttggta acgagcctta
     8341 acgtcttcga caaccgcttt aaacttagat tctatacttg cataaagaag gtctgagtgg
     8401 tcaatacgtt gaacaggacg gtttgttggg attggaataa cacgaatgtt gtagatttca
     8461 cggaattctt cttcctcagt cttacctgta cccgtcatac cagacaattt cttgtacata
     8521 cggaaaaggt tttggtacgt gattgaggca gatgtcttgg tttcatcctg gattggcaca
     8581 ccttctttgg cttcaatagc ttggtgcaat ccatcagaat aacgacgacc ttccatggta
     8641 cgacctgtaa attggtcgac aatcaagatt tcttgctctt cgctcaccac atagtcaata
     8701 tcgagaagca tgatgtagtt ggcacgaagg gcgttatcga taaagtgggt caaagccacg
     8761 ttttcgatgt catagaggtt ttcaagtttg aagtagcttt cagccctgtc aatccctgaa
     8821 tcagacaaac caatagtctt agactgcaca tcgatgatgt agtcatcttt gttcaaagat
     8881 tttacatagt ggtctgccat gtgatacaac tgactggttt caaccgcatt ggcacctgat
     8941 acaatcaaag gtgtacgagc ctcgtcaatc aagatagagt caacctcatc gaccaaggca
     9001 tagttaagcg gacgttgtac catgttttca gcgcgaacga ccatattgtc acgaaggtag
     9061 tcaaatccga tttctgagtt agttgagtaa gtaatatcac actcataggc ttcttttttc
     9121 tccattggag atttggtagc caagttaatc cctactgaca aaccaagcca agagtacaat
     9181 tcacccatct cagtcgcgtc acgttctgac aggtattcat taaccgtaac tacgtgaacc
     9241 cctttacctg aaagggcatt gaggtatacc ggcatggtcg cagtcaaggt tttcccttcc
     9301 cctgtacgca tctctggcac gtcaccatgg tgaagaacaa tcccccccat gacctgaacc
     9361 ttataaggga agagacctag gacacgtttg gcaccttcac ggacaaccgc aaatgcttcg
     9421 taaagcaatg aatccagtga ttctccattt tgataacgtt ccttaaattc aactgttttt
     9481 gcttttagtt ggtcgtcagt caaagcagcc atttggtctt cgtatttgaa aaccttgtca
     9541 gccatctttt ccagacgacg gatttctcct ttatcatttt cgataattgt ttttaaaata
     9601 ttagccatgt ttttccttac tttaaattcc gaatatttta gaatgttcct ttaattttag
     9661 cacaattact gattattttc aaggaagaat ccccattttg aaaaggaaaa agaggttagt
     9721 tttcaagcta acctctccga cttttatgat gctttaattg ccaaaaatcg gcaaaatggc
     9781 aaatgtgata aataagttaa tccaaagaga aagacagcaa atcagtccaa aaacaaagag
     9841 actgactttc ttggacagca aggccatcaa aatggacaga attccaaaag ctagcaagat
     9901 tttctgtatg atgaagatgt caatccttac ccccagaatc gctctatccc aagggataaa
     9961 gaagaaagtc agccagatca gcagaactaa accaatataa accttggaat agcgtgtaat
    10021 aaatgatttt agatgtgcca taagccatct cctaggattg tatatccttt acatattgta
    10081 tatgtccatt ttcgacagct aatacatctg tacaaaggtc tgaaatatct ttcgatatgt
    10141 gcgacgtcag gataaccaga ccattttctt ttttcaggta agataaaatg acctgtttgg
    10201 ttaacctcac actcttctca tccaaagcat tcataggttc atcgagaaag agtatagaag
    10261 gagaggaaat aaaggcttga atcaaggcca ttttttgctt tgttcccaag gataaatgac
    10321 ggtattcaac gtcttcaaat tcctgtaaat catagtattg aatccaatag gcaattcttt
    10381 tttccgtaac tttagatgaa aaatacctta acagttccaa attttctctc agggataaat
    10441 gagataaaaa ctcgactttt tcaattaaaa ttcctgcatc ctgaatataa tgatttttta
    10501 ccccgtaaac tttaccatct tgaagaactt ttcctttgtc aagcttaata taaccagcaa
    10561 gtatctttaa aagaaccgtc ttgccagatc cattattacc tttaagtcca taaatttttc
    10621 ctgattgaaa caccaaattc aactgattta aaataggtct tttcccataa attttctgtc
    10681 catttataat ttcaagtctc atcgtttatc ctttcttaaa tttctcttcc aagcgactaa
    10741 gaatcaacat aactaataag cttaagagta ctaaatacac tgttacaata tgatccatca
    10801 tccattcttg tcccacaaat gccaaaaaat agagaaaaaa agaaaaacca gcgcccgcac
    10861 taatcagtgc tatcagataa gacagtagta agtacaacat cattaactga gcaagtaaaa
    10921 agaaaagtgc gactgttttg aaatgaattc ctagaggaag taaaccaaga aaccagacaa
    10981 acaaatcttg agtaaaaaat ttagaaatga caaccaatcg tttccttgta taatcgaaaa
    11041 aggagcttga ttgatagcga atcaagtgat ggtaatggtc tgccaaatca ctttcaagta
    11101 aaatgacaga gagccatcct accatgaaaa gcgaaaggtt taacaagagt ttggggattt
    11161 ctaaattcac ttcagaatag tcattatagg aaaaaattga aatcaattct ctcttgaaaa
    11221 agataacagc atcctgcttt tgaaccgctg ttgacaatag atggtttatc aaaatcatca
    11281 tcagaactat acgaagtagt aaaacaatct ttctctttag caaaatattg ttaaaattct
    11341 taaacattat cttcatattt ttcaagcacc atgtaaggga caatataaag gatataagga
    11401 gtaaagagtt tcatcaaact tacatcccca tagctagctt gcatcaaact cgtcatagga
    11461 accatatagt aaggcaaggc actatagagc agcatagaac caagccaaag aaacatcaaa
    11521 taggtgattg ccgaacgagt cacatttcct aaataatcaa ctatttgtaa aaaatagact
    11581 gcattgatga aaataccgat tagtaggaca caagtaaaga acaaatagct tgttatctct
    11641 ccatctagga gcctttgtaa actactccca tcagaaaata gagaattcca tccaagagga
    11701 gaaaaagtcc caaagaaatg agttaaaatt gcaattatca gcacagtcac taaatatatc
    11761 aaacaaggga tacttgcaac ttgcaaagtc aactttcttt ttaacccttg ataactcact
    11821 tctcttccaa tactcaatcg taaaacttta tttttcagct caatatattg aaaacctagc
    11881 aaaacaatga tgattggaat aataaatgat tgataaaaac ctagattgaa ctggagaata
    11941 cgaaaatcta atgctgattt taataagtca tttttaattg cttgtccatc gaatttagct
    12001 agatcgggcg catgaatatc aaaaaagaaa taagtcatca aaacatcacg ataaaccaaa
    12061 gcaagaaaaa gcaaagtaag caagacataa acaaatttat gccttgccaa agttaagaga
    12121 ggaatcttca taagccacct cctacaaata gaaagtaata taatactcaa tgaaaatcaa
    12181 agagcaaact aggaaactag ccgcaagttg ctcaaagcac tgctttgagg ttgtagataa
    12241 gactgacgaa gtcagttaca tatataatcc aaggcgacgt tgacgtggtt tgaagagatt
    12301 ttcgaagagt ataaatcaat gccttccgcc tttagacttc cctagttccc gtctcaagtc
    12361 aagcattttt ttgaaacaga tatagtctaa ccagtcacta gcaaaagcga taagtagtaa
    12421 taatagccaa ataccccata acttgatgtc tgccacattt ctcaagacga tattgaaaaa
    12481 cagaactgaa aaaactgtcc aagcaaggct aaaaagagca tagagggtga tgtaaatcca
    12541 gtaaaaatag taaaaaattg ggaaaaattt actttctcta ttatccttgt caatccagct
    12601 gaaaaagtaa aaacagggta ataagattat cattttaaac aagtgttcca tcacaagcct
    12661 ccttttttaa attgttttct ttagtttcgt tctattaaat gttattacca atataaacct
    12721 tggaatagcg tgtaataaat gattttagag gtaccataag ccacctccta caaatagaaa
    12781 ccgatataaa tcaatgcctt ccacccttag acttccctag ttcctgtctc aagcgaaaca
    12841 tttctttgaa acaggaataa gttaaccaat tcataccaat agctagcaga ataaaaagaa
    12901 accaaatgcc ccataacttg atatctgtca catttctcaa gacggtattg aaaaacagaa
    12961 ctgaaacaac tgtccaagca aggctaaaaa gagaatagaa ggggatgtaa aaccagtaaa
    13021 aataataaaa aattggaaaa aacttactat ttctgttggc cttctcaatc cagttatcaa
    13081 aataaaagta cggtgctaaa agtaagaatt taaacaaatg ttccatcacc gacatcaccc
    13141 tccttctttt gatagcgttt tctattattt tattatatca aaaaaatccg gaactgtcat
    13201 tccagattct acttttttat ttgcgttttc ttgcgatgag atgaatcggt gttccctcaa
    13261 aaacaaaggc cttgcggatt tgattttcca agaaacgcag gtaagaaaag tgcatgagtt
    13321 cttcttcatt gacaaagatg acaaaggttg gtggtttggt tgccacttgg gtcgcataga
    13381 aaatcttgag acgttttcct ttgtctgtcg gtgttgggtt gatggcaatg gcatccatga
    13441 tgacatcgtt caagacagct gatggaatac gtgtattttg actttcgctg atttgcttaa
    13501 tcatctcagg aagtttgtgg agacgttgct tggttaaagc tgatacaaag ataatcggtg
    13561 cgtaaggcag gtattggaac tgctcacgga tatcttcttc ccagtttttc atagtgtggt
    13621 tatctttttc aagcgtatcc cacttgttga ccacgataat catcccttta ccagcttcat
    13681 gggcaaatcc tgcgatacgc ttgtcgtact cacgaatgcc ttcttccgca ttgatgacca
    13741 tcaagaccac atctgaacgg tcaatagcac gcatggcacg cataacagag tatttctcag
    13801 tattttcata aaccttacca gacttacgca taccagccgt atcaatcatg gtaaactctt
    13861 gaccatctgt atctgtaaag tgggtatcaa tggcatcacg agttgttcca gcaacaggac
    13921 tagcaataac acggtcttct cccaagatag cattgatcaa gcttgatttt ccaacgttag
    13981 gacgaccaat caagctaaac ttaatgacat ctggattttc ttcctcatat tcatttggaa
    14041 gattttctac gatcgcatct agcacatccc ctgtaccgat tccatggaca gatgagatag
    14101 gcaatggttc acccaaaccg agagcataga aatcatagat atcatttctc atctcagggt
    14161 tgtccacctt gttgactgcg aggataactg gtttgtgggt cttataaagc ttacgagcta
    14221 cgtattcgtc tgcatcagta attccttcct taccagacac gacaaaaacg ataacatctg
    14281 cttcttccat ggcaatttct gcctggtgct tgatttgttc catgaaagga gcatcgacat
    14341 catcaattcc tcctgtatca atcatgctaa aagaacgatt gagccactca cccgttgcat
    14401 aaatacggtc acgtgtcact ccttcgacat cttctacaat ggagattcgc tcaccagcga
    14461 tccgattaaa tagggttgat ttcccaacat tgggacgtcc tacaatggca atagttggta
    14521 gggccataat ttctcacttt ctacaataat ttcttctgtt caagattttt tctagttgag
    14581 cttggttcag cttgaccaaa ctgttctgct aggcgctgac tccagcttgt ggtcgcacgc
    14641 gccccagcat agtcagcctg aacacggtca taagcttgga ttgcctcagt tgactgttct
    14701 tggtattctt cctcaaagac aacattctct agtggcagtc ttggtttcat atcatgatgt
    14761 tgatttggca cacccagtgc catcccaaag acagaatagg tgtagtcagg taggttaaag
    14821 agctctgcca cttcttcaga cttgtatcga accaaaccga taatcacacc accatagccc
    14881 aagctttcag ctgccaacaa ggcgttttgt ccagcaagag ctgcatcgac cgaactaatc
    14941 aagagacctt ccacaccttg gggttggaag gtgtcggtat gaagtcgggc tcccttttct
    15001 gctcggttca aatctccgac aaagagaagg aaaacagcag actggcgaat ggcttcttga
    15061 ggtaccaatt catacaaggc atctttcttc tcttgacttc gtaccacaat cacagagtag
    15121 gattggaaat tcttccaaga tgatgccatc tgggctgctg tcaaaatctc atttaagtct
    15181 acttggggaa tttcttgctc tttaaacctg cgcactgaag tatgagcctt catcaattta
    15241 atggtttctg tcatcgacgg tttactcctt ctaaacgagt ctcctcagcc aaataacgga
    15301 tgcgttccat gacccgtctg gcttcccagg tttcgtcatt tccatgtttc actttcgcaa
    15361 aatgcttctc caaatcttca aagttgaagt tggatgtgaa aaaggtcggt aaattttcct
    15421 gcatccgata ttggagaatg acctgcagga tttcgtcacg cacccaaacg gttgattgct
    15481 cggcgccaat atcatctaaa atcaggacct cagacagctt aatctcatcc accaaggtct
    15541 taacattgcc atcactgata gcatttttga catcaatgac aaagctagga tagtggagga
    15601 gagtggatga tacaccacgt ttttctgata aatcatgagc tagggcagcc accatgaaac
    15661 ttttacccac accaaagtct ccatacaagt aaagaccttt caaattattg gggtaatcgt
    15721 taacaaattc tatcattctt tttagaacag ttaagcgctg aacatcatca cgataaacat
    15781 ctaaaaaact gacatttttc aggctagatg gaaaattaat taagttgaga cgtttcttga
    15841 tagccgcttc tttttcagct gcgattagtt caggagtttc ttcataagaa acatctgcat
    15901 agccatggtt catgactaat ataggcttgt agcctttggc aatataatct gtatctcctc
    15961 ggaggaattt atctctctca gtgatgtatt ggttaaactt ggaaatacta cggttcaact
    16021 cgtcctgatt gagggattct tgctggacaa aggccgcaac atcaggatcc ttcatgattt
    16081 tctgaactaa atcttgatag tgaaaacgac ttggttgacg tttgagtaca tctccgacac
    16141 tttccatcta atcacctccg ttatctaatt ttgctaataa ttctagggtt tggcgttcca
    16201 tctcttctaa ttcctcagcg gatgacgtat ttttatattc aggattactc catttaggaa
    16261 tattggtttt tgctggggca gtctgattct gtttttgtgt ttttgctttc tgttctcgct
    16321 cacggatgcg caagactgcc ttttctgccg aatgaatctt ttgataggca tagtcattgg
    16381 ctaccttcat ggcatatttc tcattgatat ttgccgaatc gaccttatta aaggtcaata
    16441 aaagaatgat attgatgact tcgtccagca agcccaagcc agccatctgt tgcaagagtt
    16501 ctctttctgt ttgggtaatg gttcccttgc gtgtttgctt gatttctgcc aagaactgca
    16561 gggcagtttt acttttggct tctttgataa tggttgtttc cttaagacta aagtcagagg
    16621 aaactggttt ttgagcaatt ttttcccgca tgcgtttggt tgaaataacc tgagaaacag
    16681 ctgttgactt ggccaattga taggtttcaa accaagtcca tttcttctcc tcggcaatag
    16741 caaagaggtt taagacatcg gactgctcat ccgcaaaacg aagtccatct cgagccatca
    16801 gctggcgaaa atggtccaag tcaaaatcgt tggccacttt cttcttgaga ccaaggtctt
    16861 cttgactgcc tagttctgcc aattctggaa agacttgatt gagtgagaca ggtatttctt
    16921 caccatcagc actttcaact ttcaaatcct ccacagctac atcgccaatc tttttctcta
    16981 agagtctgcg ataaacagga tgctccaaga agtcttgact agatagagga gcatggagga
    17041 ctagctgata aacatccccc ttttgataga gggtcaagag attaaaagca gataagattt
    17101 tcaatgattt tatcagtcta tccatcccaa agttaagatg gttgagaatg cttgaaaaaa
    17161 gatattcctt tctaccatta tcccaaaaac tgattgtata aagataaagg ctcagtgcct
    17221 cctgaccgat aatcgggagg tagcactgta ccagagatga ggtatcttgc gacacccgat
    17281 tattctttag ataagaaaaa cggtcaattg gcttcattta tctttccttt ttctttttag
    17341 aggactgggt gatttgttgg agcaagctct ctaactcact gacatcctta aaactacgat
    17401 agacactagc aaaacgtaca taggtaatct cgtccaattc agccaactcc tccatgacga
    17461 gtgaaccaat gtcctcactt tgaatttcat tttcatttcg accacggagt ttctgttcga
    17521 tacgattgac taccatgttg atttcatcac ttgacacagg acgtttctgg gctgagcgga
    17581 taatcccatt aaagatttta tctctggaga attgttcccg tgtgccatct tttttaacaa
    17641 ccactaaggt tctttcttct actcgttcgt aggttgtaaa acggtgttgg cattcgtcgc
    17701 actcacgtct tctacgaatg gtgttccctt cttctgcttg gcgactatcg ataacacttg
    17761 acttggtagc cccacatttt ggacaacgca tcctttccct ccttatcgtt ttcttttcat
    17821 tataccattt tttaagcgat tcccaaaaca attcttcttt ttgcttgaca agttttttgt
    17881 tttgttgtat tatttaatta agacaaaagg gtaaaagaaa ggagactaag atgtcctgga
    17941 catttgacaa caaaaaaccc atctatttac agattatgga gaaaatcaag cttcagattg
    18001 tttcccatac actggaaccc aatcaacaac ttccaaccgt gagggagcta gctagcgagg
    18061 ctggtgtcaa tcccaatacc atccaaagag ccttatcaga ccttgaacga gaaggatttg
    18121 tctacagcaa gcgaacaact ggacgatttg tgactaagga taaggagcta atcgctcagt
    18181 cacgcaaaca attatcagaa gaagaattgg aacacttcgt ttcctccatg acccattttg
    18241 gctatgaaaa agaagaacta ccaggcgtag tcagtgatta tattaaagga gtttaagcct
    18301 atgtcattac tagcatttga aaatgtatcc aaatcatatg gagcaacacc agcccttgaa
    18361 aatgtttctc ttgacattcc agctggaaaa attgtcggcc ttcttgggcc aaacggctca
    18421 ggaaaaacaa ccctgattaa actaattaat ggcctcttac aaccagatca aggacgtgtc
    18481 ctcatcaacg acatggaccc aagcccagca accaaggccg ttgtagctta tttgcctgat
    18541 acgacctatc tcaatgagca aatgaaggtc aaagaagccc taacctactt caagaccttc
    18601 tataaagatt tcaatcttga acgcgcccat catctacttg cagacctggg cattgatgaa
    18661 aatagtcgtc tcaagaaact atcaaaagga aacaaagaaa aggttcaact gattttggtt
    18721 atgagccgtg atgctcgtct ctatgttttg gatgaaccca ttggtggggt ggatccagca
    18781 gcccgtgctt atatcctcaa taccattatc aacaactact caccaacttc taccgttttg
    18841 atttctaccc acttgatttc tgatatcgag ccaatcttgg atgaaattgt cttcctaaaa
    18901 gacggaaaag tcgtccgtca aggaaatgta gatgatattc gctacgagtc aggtgaatcc
    18961 attgaccaac tcttccgtca ggaatttaag gcctaagcaa aggagattat ttatgttttg
    19021 gaatttagtt cactacgaat ttaaaaatgt taacaagtgg tatttagccc tctacgcagc
    19081 cgtgctagtc ctttctgccc tcatcggaat acagacacaa ggctttaaaa atctacctta
    19141 ccaagaaagt caggctacta tgctactttt tctagctaca gtctttggtg gcttgatgct
    19201 tacacttgcg atttcaacca ttttcttgat tattaaacgc ttcaaaggta gtgtctacga
    19261 ccgacaaggc tatctgactt tgaccttgcc agtttctgaa caccatatca tcacagccaa
    19321 actaatcggt gcctttatct ggtcattgat tagcaccgct gtattggctc taagtgctgt
    19381 tattattctg gctttaacag ctccagaatg gattcctctt tcttatgtga ttacatttgt
    19441 agaaacacat ctccctcaga tctttcttac aggtatatcc ttcctactaa ataccatttc
    19501 aggaatcctc tgcatctacc tggctatttc cattggacag cttttcaatg aataccgtac
    19561 agcactcgct gttgcagcct acattggtat ccaaatcgtc attggattta ttgaactttt
    19621 cttcaatctt agttccaatt tctatgtcaa ttcactggta ggactcaatg accatttcta
    19681 tatgggagca ggtatagcca ttgttaaaga actcatattc atagctatct tttatctcgg
    19741 aacctactac atcttgagaa ataaggttaa tttgctttaa ataattttta cctagatatg
    19801 taacatactc atagaacaaa agagaccagg caaaaagtct ttaaaattag aaaacgcata
    19861 gtatcaagtg ttaaaaatcc ttgatattat gcgttttttg tgagctgact tatttccttt
    19921 cgctatatcg caaaatgaaa taagaacgga acgatgggat tttggaattc aaatcaattt
    19981 ataagaatgt tttagaagta atattatcct attccagatt cagttcacta tacaattgag
    20041 ttttcaagca acctgtttac ataatgtgta cataattagg ttcgtgattc cacccttttc
    20101 acctttaaaa acctcgcttt cgcaaggctc ttctatttat aagataaggc acgtttaaag
    20161 gttttccaaa tccctaaatc atccgtttga agaacgagac tagcatacat gcgtccgata
    20221 aatcctgttg ctaccaccgc aaaaatcact gtaatagcaa gtgaaatcca tgcttctgct
    20281 ccccccgcat agccattaat cgttcgaaac ggcataaaga aggtcgaaat aaagggaata
    20341 taagaaccaa tcttcaagag gagattgtca ccagctgcac ctagagctgt cactccaaaa
    20401 aaaccaccca taatcaaaat catcaaaggc gacaaggctt tccctgagtc ctcaggacga
    20461 gaaaccatag atcctaggaa ggctgccaag actacgtaca tgaaaagact gatcaaaata
    20521 aagagcaagg tattcagtga gatagcatct cccaagtgat ccaaaatacc agactgagcc
    20581 aagaatggca aatctttaaa gagcaaaacg gcagccagac cacctacaac atagatccca
    20641 atatgcgtta aaatcactag aaacagagcc atcatccgcg catagaaata gtgacttgcc
    20701 cttatgctag aaaaaacgac ttccataatt ttggtgcctt tttcactggc aacttcctga
    20761 gctgttacac ccgcataggt aatcagaatc atataaagaa agaatcctaa ggcacctgct
    20821 gcaattgttt gaataaactt tttattttcc ttggcttcat caatcttttc tgtgaattga
    20881 attgtctgcg ctaagcgttt ttcctgctct tgagacaagg aagcagttga acgattaagc
    20941 tgattttgca gttcattgag tgtacctgta acctcaaatt taattccatt ttcaagcgat
    21001 gtttcgccat gataaactgc ctttagaaca ctatcttctt gatcaatggt caaataacct
    21061 tttaattttt cttctttaat tgcttctttg gcacttgctt cgtctttata gtcgaagtta
    21121 acaccattta cattcttcag tccttctgct acagatggca ctgttgtcac tactgccact
    21181 ttattatttt tagccataga agaaccttgg atatgcccaa ttcctacaga gattcctaaa
    21241 aagaggaacg gcgaaatcac cataaagaag aaactccatg actcgacatg tcgaagatag
    21301 gtttccttga ttacaaccca catatttctc atacttccac tcctgattct agtttaaaga
    21361 tttcatcgat agttggcgct tgttggtcaa atgttgcgat atattgacct tgagtcaaga
    21421 ttgggaagag ttcccttcca gcgctctcat cctccaaaat caatttccaa ctgccttgtt
    21481 tggtcaagct cacctgtttg acatgaggaa gattttccaa ttcttccttg cttcgttcac
    21541 ttgaaacaaa gagacgcgtt ttcccgtatt gattgcggac atcctgaact ggtccgtgca
    21601 agaccacacg gccatctcgg atcatcagaa tatcgtcaca aagttcctca acattggtca
    21661 tgacatggtc agaaaagata atggttgctc cgcgctcttt ttcctgaaaa atgacttgtt
    21721 tgagcaattc tgtattaact gggtccaatc cactaaaagg ctcatccaag ataatcaggt
    21781 ctggttcatg aatcagagta ataatgagct gaatcttctg ctgatttcct tttgacagac
    21841 tcttgatttt atctgtcagc tttcctttca cttccaacct cttcatccat tgagggagtt
    21901 tttctttgac ttctttggca tccatgcctt ttagagtcgc caagtagcga acttgttcaa
    21961 gaactgtcaa tttaggcatg agactgcgtt cttcaggcag ataaccaatc cgagcatagg
    22021 tctcctgacg aatatcctga ccatccagac cgatttctcc ctgatattct aggaatttca
    22081 aaatactatg gaaaatcgtt gtttttccag caccattttt tccgactagt cccaaaatac
    22141 gacctggtcg cgcttgaaag tcaataccaa acaaaacttg cttggagcca aaacttttct
    22201 ctagacttct tacttctagc atctttcacc tccgaaattt cttgcactca ttatactcct
    22261 ttttgatagc ctttacaatg tttttgtcca tttttagaag actattgctg tgtaaaatat
    22321 ggcctggagc acttttatac tcaatgaaaa gcaaagagcg aactaggaag ctagccgtag
    22381 gctgctcaaa gtacagcttt gaggttgcag ataaaactga cgaagtcagc tcaaaacact
    22441 gttttgaggt tgtggataga actgacgaag tcagtaacta tatctacggc aaggcgaagc
    22501 taacgtggtt tgaagagatt ttcgaagagt attagtgata aatccattat acagtagcaa
    22561 actcaattta taccttccgc tcctcaactg tctattttta atcctgaatt gttatttgag
    22621 taactccttt ttcctcataa agttttcttc ctctaaaact tctggaaaaa agcgaatagt
    22681 ttcagacaac atttttataa gaaacaagtt catctgtcat ttcaagaagg agtaatcctt
    22741 tatctactaa tggacggaac ggaattcaac cgcttgtccg atatattttc taaggattat
    22801 atagtaaaat gaaataaaaa caggacaaat agatcgggac agtcaaatcg atttctaaca
    22861 atgttttaga agtagatgta tactattcta gtttcaatct gctatatcta ttatgcacac
    22921 cactatagga tctaataaaa atcacaacaa gttcattcat agatggttac ctcagggaac
    22981 taagaaaacg actacaaagg aagtcgcatt catcgaaaag tggattaaca actatcctaa
    23041 aaaatgcttg aactacaagt cccccagaga agacttctgg atgactaact tgaacttgaa
    23101 atttagcaat aattaattca ccatctaact atatttagta attatttcag aactgattaa
    23161 tattaaaatt aactaacaat tcaaaggatt catactagcc ataaattacg tccatcagag
    23221 agagactctt actactttta gattttagtc tttctagctt cagaatacat ctaaacttta
    23281 gggaaaatga ctattcgaaa gcgcgaatgc ctcaaaatta tctcagataa gctattcgaa
    23341 acttagaatg cttttaaatt tatggaattg cgattattcg aaacctagaa tgcatataac
    23401 ctttagttga cagacctatt ctaagtctcg aagggctatt tactttctat tccttatcaa
    23461 aaaagactca ttcccccttt ctcctccaaa atatggtata gtagaaatat actatctatg
    23521 aggagtttac atgtcacagg ataaacaaat gaaagctgtt tctccccttc tgcagcgagt
    23581 tatcaatatc tcatcgattg tcggtggggt tgggagtttg attttctgta tttgggctta
    23641 tcaggctggg attttacaat ccaaggaaac cctctctgcc tttatccagc aggcaggcat
    23701 ctggggtcca cctctcttta tctttttaca gattttacag actgtcgtcc ctatcattcc
    23761 aggggccttg acctcggtgg ctggggtctt tatctacggg cacatcatcg ggactatcta
    23821 caactatatc ggcatcgtga ttggctgtgc cattatcttt tatctagtgc gcctatacgg
    23881 agctgccttt gtccagtctg tcgtcagcaa gcgcacctac gacaagtaca tcggctggct
    23941 agataagggc aatcgttttg accgcttctt tatttttatg atgatttggc ccattagccc
    24001 agctgacttt ctctgtatgc tggctgccct gaccaagatg agtttcaagc gctacatgac
    24061 catcatcatt ctgaccaaac cctttaccct cgtggtttat acctacggtt tgacctatat
    24121 tattgacttt ttctggcaaa tgctttgaca cgtaaaaaat ccgtttggtt tcccaagtgg
    24181 atttttaaag cgtagattaa ctatagcttg atactaaata tactttggta tggaaattat
    24241 gcatattttt cgatagtgag gcgaggactt acctagcctt tccgccgtga tagaaacacc
    24301 tgaaatctaa tggtttcagg tattcggaaa ctttgagaca ctaggctcaa agtttaggta
    24361 tggaatttcg aagaaagtcg ctaccgtccg taatcactta aggaaaggct caaaaatatt
    24421 gttttcaacc acaaaatccg tttggtttcc caagcggatt ttgtgcttta ttttgaaact
    24481 tcttttgcaa gaacaaagtt cccaagtgtg gcagaaccat ttcctgcgac tgctggcgtc
    24541 acgatatagt cacgcacatc tggtactggt aggtaaccat taagaagaga tgtaaatttc
    24601 tcacggacac ggtccagcat atgttgttga gccatgaccc ctccaccaaa gacaatcacg
    24661 tctgggcgga aagtcactgt cgcattaacc gcagcttgag cgatatagta ggcttgaaca
    24721 tcccaaacag ggttgttgag ttcaatattt tccccacgta cacctgtacg agcttccaaa
    24781 cttggaccag ctgcataacc ttctagacat cccttatgga aaggacaaac acccttaaac
    24841 tctttttcaa tatccattgg gtgtctagca acataataat gacccatttc agggtgaccc
    24901 acaccaccga taaactcacc acgttggatg acgcctgcac cgatacctgt accgattgtg
    24961 tagtaaacca agttttcgat acgaccacca gcattgttac gggcaaccat ttcaccgtaa
    25021 gcagagctgt ttacgtctgt tgtgaagtac attggcacgt ttagggcgcg acgaagggca
    25081 ccaagcaagt ctacatttgc ccagtttggt tttggagtcg tcgtgataaa gccataagtt
    25141 tttgagtttt tgtcaatatc aatcggccca aatgaaccaa ctgcaagacc agcaaggtta
    25201 tcgaattttg agaagaactc aatggtttta tcgattgttt cgattggagt tgttgttgga
    25261 aattgtgttt tttctacaac gttaaagttt tcatcaccga cagcacagac aaactttgta
    25321 ccgcccgctt ccaagcttcc atataatttt gtcatgataa acctcttgtt tttattttct
    25381 ttattatagc atacttcgaa agtctaaatg tctctatttt ttagattttc ctctgtaaat
    25441 cttactatct aataaaaacg aacaaacatg tcatttgttc gttttcacat tagagaggat
    25501 tgattagatt ttcacttcga tcacagcatc ccccttcgaa actgaacctg ttgcgactgg
    25561 agctactgaa gcgtagtcag ctgtatttgt aacgataacc attgttgtat catcaagtcc
    25621 agctgcagcg attttgtttg agtcaaatgt tccaagaaca tcgccagctt tcaccttatt
    25681 accttgagca acttttgctt caaaaccgtc accgttcata gatacagtgt caataccaac
    25741 gtgaatcaaa acttcagcac catttcttgt tttcaaacca aaagcgtgcc ctgttggaaa
    25801 ggcaattgaa acttcagcat cagctagtgc atagaccacg ccttgacttg gtttcacagc
    25861 gataccttgt cccatagctc cacttgagaa gactgggtca ttgacatcag caagagcgac
    25921 aacatcaccg acgataggag ttacaagtgt ttcattttga agagctgctg gcgcaacttc
    25981 ttctttttct tcagccactt cagcttgttt tgcagctgca gttgcgtcta cttcatcttc
    26041 gtaaccaaac atgtaagtaa gagcaaaacc aagggcaaat gatacagcta ccataagaag
    26101 gtattgtgga agttgtccgt taccaacata aagcattgta ccagggatga tggtgatacc
    26161 attaccagta ccagcaagtc caaggataga agccaatcca ccaccgattg caccagcaat
    26221 caatgaaagg aagaatggtt tacggaagcg caagttcacc ccgaagatag caggctctgt
    26281 aatacctagg aaggcagaaa gagcagccgg gaaagcaagt gttttcagtt ttggattttt
    26341 tgttttaaca ccaaccgcaa cagtagcagc accttgagct gtcatagcag ctgtgatgat
    26401 agcgttgaat gggttagcat ggtcagcagc aagtaattgc acttcaagca agttgaagat
    26461 gtggtgcaca cctgacacga cgatcaattg gtgaacccca ccaatcaaga aaccaccaag
    26521 accaaatggc atgctaagaa tcgcttttgt agcaataagg atgtagtttt caacaacgtg
    26581 gaaaactggt ccaatgacaa agagtccaag gatagacatg accaaaagtg tcacgaatgg
    26641 tgttaccaag aggtcaatga catctggaac aaccttgcgg acagcttttt caaatttagc
    26701 tccgacaacc ccgatgatga aggctggaag aacggaacct tgcaaaccaa caacagggat
    26761 gaaaccaaag aagttcatcg ctgttacttc accaccttga gcaactgccc aagcgtttgg
    26821 aagtgagcca gagacaagca tcataccaag aacgatacca acggcaggat ttccaccaaa
    26881 tacacggaag gttgaccaca caaccaaacc tggcaagatg atgaaggctg tatctgtcaa
    26941 gatttgtgtg taagttgcaa agtcacctgg aagtggcatt tcaagagcgt tgaaaagacc
    27001 acgcacaccc atgaagagac ctgtcgctac gataactggg atgattggaa cgaaaacatc
    27061 accgaaagta cggatagcac gttggaacca gttcccttgt ttagcaactt ctgctttcat
    27121 gtcatcctta gatgatgttg gtaagccaag tacaacaact tcatcgtaca ttttgttaac
    27181 tgtacctgta ccaaagataa tttggtattg ccctgagtta aagaaagcac cttgaacttt
    27241 ttccaagttc tcaatcactt ctttattgat tttctcttca tctttgacca tgacacgtag
    27301 acgagtcgca cagtgggcaa cactattgac attttcacgt ccgcccaagg catcgatgac
    27361 tttttttgca atttcctgat tgttcatttg caaaaatctc cttatataac attttgttct
    27421 tgtttgaaag cgattttatt cgcccttacg actattattt tatcatgttt taaaaatatg
    27481 tcaagcgttt tgcagaaaaa atattctatc cacttagtgg gcaagtttta gattgattgt
    27541 ttttgactgt ttcatcagga attccttgaa aaataagttt gaaaccttgg ttaaaaagtc
    27601 ttttatttca ttatctttca cattttcgta aaaatttgat tgatttcctg tatttatttt
    27661 atgataatcg tttgacagtt tttcctcttt tttaacataa aaggcttgca ttttttatcg
    27721 aaaacagtta ctattaaaag tgataagatt tttggaggaa tgaatggaat ggacaactga
    27781 gcgtcgttac agactttatc aagattggac gcaagaagaa attcaacata taaaggaaaa
    27841 tatggcacaa tctccatggc atactcatta ccatgttgag ccaaaaacag gacttctcaa
    27901 cgacccaaat ggcttttctt actttgatgg caagtggatc ctcttttacc agaattttcc
    27961 ttttggtgca gcccacggtt tgaaatcttg ggcacagcta gaaagtgatg atttggttca
    28021 ctttaaagaa actggaatca aagttttacc agatactcca ttagatagcc acggtgccta
    28081 ctctggttct gccatgcaat ttggcgataa cttattccta ttttatacag gaaatgttcg
    28141 cgatgaaaac tggatccgtc acccatacca gatcggtgct ttgatggaca aggagggtaa
    28201 gattacaaag attgacaaga tcttgattga ccagccagca gactctactg accacttccg
    28261 cgatccacaa atttttaact ttaaaggtca atactatgct gtcgtcggtg gacaggactt
    28321 ggagaaaaaa ggcttcgtcc gtctctacaa ggctgtcaat aacgactaca caaactggca
    28381 agcagttggc gaccttgact ttgctaacga ccgtactgcc tacatgatgg aatgtcctaa
    28441 tctggtcttt gtagaggaac atcctgtcct tctctactgt ccacaaggat tggataagaa
    28501 agttctagac tacgataata tctttccaaa tatgtataag attggggctt cctttgaccc
    28561 taaaaatgcc aaaatggtag atgtgtctca acttcaaaac atggattacg gtttcgaagc
    28621 ctatgcaact caagccttca acgctcctga tgggcgtgct ctagcagtta gctggcttgg
    28681 tttgccagat gtttcttacc catctgaccg ttttgaccac caaggaacct tctctttggt
    28741 caaggaactc actatcaaag acgacaagct ctaccagtat ccagtcgctg ctattaagga
    28801 ccttcgtgct tctgaagaag ccttctcaaa ccgttcccaa accaagaaca cttacgaact
    28861 tgaactcaac ttggaagcta atagccagag cgagattgtc ttacttgctg ataaagaagg
    28921 taagggactt tcaatcaact ttgaccttgt aaacggtcaa gtgacagtgg atcgtagcca
    28981 ggctggagaa cagtatgccc aagaatttgg gacaactcgt tcttgcccta tcgagaatca
    29041 ggctactact gctacaatct tcatcgataa ctctgtcttt gaaattttca tcaataaagg
    29101 agaaaaagta ttttctggtc gtgtcttccc acatgcggac caaaatggta tcctgatcaa
    29161 atctggaaac ccaactggaa cttactatga attagattat ggtcgcaaaa ctaactgatg
    29221 tcgccaaact tgcaggcgtc agtcctacta ccgtttctcg ggttatcaat aaaaaaggat
    29281 atctatctga gaaaaccatc caaaaagtca atgaagccat gagagaatta ggctataaac
    29341 ccaacaacct ggctcgtagt ctgcaaggaa aatcagctaa gttaatcggc ttgattttcc
    29401 ccaatatttc caatgttttc tatgcagaat tgattgataa attggaacac caactcttca
    29461 aaaatggtta caagaccatc atctgcaaca gtgaacatga ttctgagaag gaacgcgaat
    29521 acatcgaaat gttggaagcc aatcaggtag acggcatcat ttctggtagt cacaacctag
    29581 gaatcgaaga ctacaatcgt gtgacagcgc cgattatttc ctttgaccga aacctatcgc
    29641 cagacatccc tgttgtctcc tctgacaact atgctggtgg ggttcttgct gcccaaacct
    29701 tggtcaagac aggtgcccag tctatcatca tgattacagg gaatgacaat tccaattcgc
    29761 caaccggact gcgccacgct ggttttgcat ccgtactccc aaaagctcct attatcaatg
    29821 tttccagtga cttttctccc gtcagaaaag aaatggaaat caagaatatc ttgacccggg
    29881 aaaaaccaga tgccattttt gcttcggatg atttgacagc tattctggtc attaaaatcg
    29941 ctcaagaatt gggcatttct gtcccaaaag agctcaaggt catcggctat gatgggacct
    30001 actttatcga aaattactac cctcaattgg ctactatcaa gcaacctttg gaagagattg
    30061 cttgtctcac tattgatctt ctcttgcaaa agattgaagg caaggaagtc gccacaactg
    30121 gttacttctt accagttacg ctattaccag gaaaaagtat ttaaacacaa gaaaactcag
    30181 accgattcgt ctgagttttt atgatcttaa attttcgaga tagcgctggg ctgtctctag
    30241 gttaaaggtt ttatctgaga tgaggcgctc tactagggga gcaacttcag attcactagc
    30301 cccagctagg agagctaggg atttggcctg tagtttcatg tggccttgct ggatgcccgt
    30361 acttaccaag gctttgaggg ctgcaaaatt ttgagcaaga ccgatggaca cgataatctg
    30421 ggctaattct ctggcagaag gatttcctag tagatcatga ctgagagcta cacgtgggtt
    30481 gaggccgata gagccaccct tagtcgctac aggcatgggc agggtcatct caccgaccaa
    30541 ttcttctctt tcaaggtcca gcgtccagca gctaagacct tgatagcgtc catctcgact
    30601 ggcaaaggca tgggccccag cttcgatggc acgccagtca ttaccagtgg caatcaaaat
    30661 cgcatcaata ccattaaaaa ttcctttatt atgagtagca gctcggtaag gatcagcctg
    30721 cgcaaactga ctagccaacg caattttctc cgcaatctct cgtccttgat ccttttggcg
    30781 gctcaagtag cgaaaggcga tgcgacagct tgcagtcacc agagaatcag tcgcgtagtt
    30841 ggacaggatt cccatgagac tctgtccctg actgagttct tctaagactg gtttcaaggc
    30901 ttccagcatg gtgttgagca tattggcacc catggcttcc tgggtatcga catgaatata
    30961 aacaacgaga aagtctggtt cgccttttat ctgctcgaca tgcagatcac gcgccccacc
    31021 cccacgttta acgatagaag gataggcttg attggcaagc tccaagagct ccgctttctt
    31081 gctggcaatc ttctcttgcg ctagtttagg attagcaact tgataaaggg ctacctgccc
    31141 aatcatctgg cgctgatgga cttgtgcagt aaaaccacct gcacgcttga tgattttgct
    31201 ggcatagctg gccgccgcaa ccacagaggg ttcttctgtc acatagggaa cggtgtattc
    31261 ctgaccgttg acaagtacct ccggaaccag tgaataaggc agagaaaaag ttcccactac
    31321 attctcactc agctggtctg ccacagtcac gctcatctgt tcatccttct ccagactagc
    31381 ttgtctctca ggactaagga gcgcctgagc ttttaacagc tcgaggcgct cttggtatga
    31441 ttttttagaa aatccattcc aacttatctt cattattttt caaccttgct ataacggcgt
    31501 tggtggtcga gaatttcaac caaggcaaaa tcttgatttt catagccagc aaactgggca
    31561 gagtttgttt catccaagtt tacttcctca aaaaagacct tttcatagtc tgcaacggat
    31621 agggcagttc gttggttgag cttgttcaaa cggtctttat ccaaataagc ttcatatcct
    31681 tcaaccaatt caccactgaa gaactcagcc acagctccac ttccgtaact ataaagggcg
    31741 attttatccc cagctttcaa gctatctgta ttttccaaga gagacaaaag tccaaggaaa
    31801 agtgaacctg tgtagatatt ccccaccttt tgactgtaga gaatagactg gtcaaaatgc
    31861 ttttgtaaga ggtctttttt ctcttgaggc aggctcttat ccatgatttt tttcaagcct
    31921 tttagcgcta atttaggata aggcaagtgg aaacaaacag ccgcaaaatc atccaaagta
    31981 agctggtagc gtttttgata ttcaagccaa gtcgttttca aactatccaa gtattgttgg
    32041 gtagaataga caccatttac ataaggagtt gtcgagtaat ttggtcgcca gaaatccatg
    32101 atgtcacggg tctgagctac attgtcatta ttaaaggcca tcatgcgtgg attttgtgta
    32161 atcaacatag ccacacttcc agcaccttga gttggttctc ccggagtttc aataccatat
    32221 ttggcaatat cactggcaat gaccaagacc ttggactccg gagaattttc cacatgcaat
    32281 ttggcataat ggagggcagc tgtcgcccca tagcaggctt ctttaatctc gaaactacga
    32341 gcaaagggct ggatgcccag caagccatgc acaaagacgg ccgcagcctt actctggtca
    32401 attcctgact cggtagccac aatgaccatg tcaacttctt gtctttcttg ctcagttaaa
    32461 atagagtcac tagcactggc cgccaaggtc acgatgtcct cagttagggg cgcaatactc
    32521 aattccttga gtaagagtcc tttacttaat ttttcagggt caattcccct cgcttctgct
    32581 aagtcttgta atttcaagac atattgactg gtcgcaaaac caatcttatc aataccgatt
    32641 gtcatattta cctctgtttt atcattcatg taaaaaatcg ttctatacta ttttatcaca
    32701 aatggcagta aaagagagaa aaaagacttg attcaccaaa tcaagcctct tattggtcat
    32761 cattttaaag aatgattagt tgctagagag ttcaccgata taagtagctt tataagctcc
    32821 attcacagtt atcagctcct ggaggatcaa atttcctgag taagtccttc ccatctcatc
    32881 tacaaatttt tgataaaact gactggtcgg aatttctctg acatccttat caaatgtctt
    32941 gtcaagtgtt ttactaacct tctcagcaat caattgatgc tcttgccatc cactttgaaa
    33001 ctctgagccc caactagaaa ccatgactgg gataaacaac aaggtcagta gacttacaga
    33061 caataaggaa aatagtagac ttcctgcaaa actagaatcc tagttcatga ttgataatgc
    33121 cagcaatcaa attcattcgt aatccgaagc gtttacgatg atttcgatag attgttgaaa
    33181 acattttaaa cgtttttact ttggcaaaga tgttctcaac cttgcttctc tccttggata
    33241 gcgcatggtt acaagcttta tcttcagctg ttagcggctt gagtttgctg gatttacgtg
    33301 gagtttgtac ttgaggatat atcttcatga gcccttgata accactgtca gacaagattt
    33361 taccagcttg tccgatattt ctgcgactca ttttgaacaa cttcatatca tg
//
LOCUS       DAVHKZ010000023        32232 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000023 DAVHKZ010000000
VERSION     DAVHKZ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32232
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.023"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(228..1316)
                     /locus_tag="VVO74_001283"
     CDS             complement(228..1316)
                     /locus_tag="VVO74_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU5695301.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALIGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTIKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            complement(1334..2002)
                     /locus_tag="VVO74_001284"
     CDS             complement(1334..2002)
                     /locus_tag="VVO74_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU5695302.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            complement(2021..4459)
                     /locus_tag="VVO74_001285"
     CDS             complement(2021..4459)
                     /locus_tag="VVO74_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU5695303.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIGGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKAALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPVTTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            complement(4610..5908)
                     /locus_tag="VVO74_001286"
     CDS             complement(4610..5908)
                     /locus_tag="VVO74_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU5695304.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            complement(5925..6233)
                     /locus_tag="VVO74_001287"
     CDS             complement(5925..6233)
                     /locus_tag="VVO74_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU5695305.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            complement(6279..6599)
                     /locus_tag="VVO74_001288"
     CDS             complement(6279..6599)
                     /locus_tag="VVO74_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU5695306.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            complement(6794..7774)
                     /locus_tag="VVO74_001289"
     CDS             complement(6794..7774)
                     /locus_tag="VVO74_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU5695307.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            complement(7787..8533)
                     /locus_tag="VVO74_001290"
     CDS             complement(7787..8533)
                     /locus_tag="VVO74_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU5695308.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            8655..9431
                     /locus_tag="VVO74_001291"
     CDS             8655..9431
                     /locus_tag="VVO74_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU5695309.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            9506..9703
                     /locus_tag="VVO74_001292"
     CDS             9506..9703
                     /locus_tag="VVO74_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU5695310.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            9921..10517
                     /locus_tag="VVO74_001293"
                     /pseudo
     CDS             9921..10517
                     /locus_tag="VVO74_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            10593..11042
                     /locus_tag="VVO74_001294"
     CDS             10593..11042
                     /locus_tag="VVO74_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000337416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU5695311.1"
                     /translation="MCTILVSIYYKIGLSSSGVYKAVADGEMTVGLSYEDPAVKLLND
                     GANIKVVYPKEGTVFLPASAAIVKKSKNMENAKKFIDFIISQEVQDTLGTTTTNRPVR
                     KNAKTSENMKPIDKIKTLTEDYDYVIKNKSDIVKKYNEVFTDIQSKQ"
     gene            11055..12146
                     /locus_tag="VVO74_001295"
     CDS             11055..12146
                     /locus_tag="VVO74_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695312.1"
                     /translation="MSEIEIINAKKIYHDVSVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNLSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMLALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASKIQVSEESTFEEDLQKGNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGT"
     gene            12136..13781
                     /locus_tag="VVO74_001296"
                     /pseudo
     CDS             12136..13781
                     /locus_tag="VVO74_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(13884..14576)
                     /locus_tag="VVO74_001297"
     CDS             complement(13884..14576)
                     /locus_tag="VVO74_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU5695313.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(14820..16157)
                     /locus_tag="VVO74_001298"
     CDS             complement(14820..16157)
                     /locus_tag="VVO74_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU5695314.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(16167..16433)
                     /locus_tag="VVO74_001299"
     CDS             complement(16167..16433)
                     /locus_tag="VVO74_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU5695315.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(16698..17084)
                     /gene="rplQ"
                     /locus_tag="VVO74_001300"
     CDS             complement(16698..17084)
                     /gene="rplQ"
                     /locus_tag="VVO74_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU5695316.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(17096..18031)
                     /locus_tag="VVO74_001301"
     CDS             complement(17096..18031)
                     /locus_tag="VVO74_001301"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU5695317.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(18074..18457)
                     /gene="rpsK"
                     /locus_tag="VVO74_001302"
     CDS             complement(18074..18457)
                     /gene="rpsK"
                     /locus_tag="VVO74_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU5695318.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(18475..18840)
                     /gene="rpsM"
                     /locus_tag="VVO74_001303"
     CDS             complement(18475..18840)
                     /gene="rpsM"
                     /locus_tag="VVO74_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU5695319.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(18858..18974)
                     /gene="rpmJ"
                     /locus_tag="VVO74_001304"
     CDS             complement(18858..18974)
                     /gene="rpmJ"
                     /locus_tag="VVO74_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU5695320.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(18999..19217)
                     /gene="infA"
                     /locus_tag="VVO74_001305"
     CDS             complement(18999..19217)
                     /gene="infA"
                     /locus_tag="VVO74_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU5695321.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(19334..19972)
                     /locus_tag="VVO74_001306"
     CDS             complement(19334..19972)
                     /locus_tag="VVO74_001306"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU5695322.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLT
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            complement(20123..21433)
                     /gene="secY"
                     /locus_tag="VVO74_001307"
     CDS             complement(20123..21433)
                     /gene="secY"
                     /locus_tag="VVO74_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU5695323.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(21446..21886)
                     /gene="rplO"
                     /locus_tag="VVO74_001308"
     CDS             complement(21446..21886)
                     /gene="rplO"
                     /locus_tag="VVO74_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU5695324.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(22031..22255)
                     /gene="rpmD"
                     /locus_tag="VVO74_001309"
     CDS             complement(22031..22255)
                     /gene="rpmD"
                     /locus_tag="VVO74_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU5695325.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(22227..22721)
                     /gene="rpsE"
                     /locus_tag="VVO74_001310"
     CDS             complement(22227..22721)
                     /gene="rpsE"
                     /locus_tag="VVO74_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU5695326.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(22739..23095)
                     /gene="rplR"
                     /locus_tag="VVO74_001311"
     CDS             complement(22739..23095)
                     /gene="rplR"
                     /locus_tag="VVO74_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU5695327.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(23179..23715)
                     /gene="rplF"
                     /locus_tag="VVO74_001312"
     CDS             complement(23179..23715)
                     /gene="rplF"
                     /locus_tag="VVO74_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU5695328.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(23907..24305)
                     /gene="rpsH"
                     /locus_tag="VVO74_001313"
     CDS             complement(23907..24305)
                     /gene="rpsH"
                     /locus_tag="VVO74_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU5695329.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(24590..24859)
                     /gene="rpsN"
                     /locus_tag="VVO74_001314"
     CDS             complement(24590..24859)
                     /gene="rpsN"
                     /locus_tag="VVO74_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU5695330.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(24877..25419)
                     /gene="rplE"
                     /locus_tag="VVO74_001315"
     CDS             complement(24877..25419)
                     /gene="rplE"
                     /locus_tag="VVO74_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU5695331.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(25443..25748)
                     /gene="rplX"
                     /locus_tag="VVO74_001316"
     CDS             complement(25443..25748)
                     /gene="rplX"
                     /locus_tag="VVO74_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU5695332.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(25826..26194)
                     /gene="rplN"
                     /locus_tag="VVO74_001317"
     CDS             complement(25826..26194)
                     /gene="rplN"
                     /locus_tag="VVO74_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU5695333.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(26220..26480)
                     /gene="rpsQ"
                     /locus_tag="VVO74_001318"
     CDS             complement(26220..26480)
                     /gene="rpsQ"
                     /locus_tag="VVO74_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU5695334.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(26505..26711)
                     /locus_tag="VVO74_001319"
     CDS             complement(26505..26711)
                     /locus_tag="VVO74_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU5695335.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(26721..27134)
                     /gene="rplP"
                     /locus_tag="VVO74_001320"
     CDS             complement(26721..27134)
                     /gene="rplP"
                     /locus_tag="VVO74_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU5695336.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(27138..27791)
                     /gene="rpsC"
                     /locus_tag="VVO74_001321"
     CDS             complement(27138..27791)
                     /gene="rpsC"
                     /locus_tag="VVO74_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU5695337.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(27804..28148)
                     /gene="rplV"
                     /locus_tag="VVO74_001322"
     CDS             complement(27804..28148)
                     /gene="rplV"
                     /locus_tag="VVO74_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU5695338.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(28160..28441)
                     /gene="rpsS"
                     /locus_tag="VVO74_001323"
     CDS             complement(28160..28441)
                     /gene="rpsS"
                     /locus_tag="VVO74_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU5695339.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(28545..29378)
                     /gene="rplB"
                     /locus_tag="VVO74_001324"
     CDS             complement(28545..29378)
                     /gene="rplB"
                     /locus_tag="VVO74_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU5695340.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(29396..29692)
                     /locus_tag="VVO74_001325"
     CDS             complement(29396..29692)
                     /locus_tag="VVO74_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU5695341.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(29692..30315)
                     /gene="rplD"
                     /locus_tag="VVO74_001326"
     CDS             complement(29692..30315)
                     /gene="rplD"
                     /locus_tag="VVO74_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU5695342.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKLVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(30340..30966)
                     /gene="rplC"
                     /locus_tag="VVO74_001327"
     CDS             complement(30340..30966)
                     /gene="rplC"
                     /locus_tag="VVO74_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU5695343.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(31183..31491)
                     /gene="rpsJ"
                     /locus_tag="VVO74_001328"
     CDS             complement(31183..31491)
                     /gene="rpsJ"
                     /locus_tag="VVO74_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU5695344.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(31757..>32232)
                     /locus_tag="VVO74_001329"
     CDS             complement(31757..>32232)
                     /locus_tag="VVO74_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU5695345.1"
                     /translation="NLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDIL
                     ALQAGMDVLTIEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELK
                     RRLARDTTVRNRYASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
BASE COUNT         9642 a         6861 c         5505 g        10224 t
ORIGIN      
        1 taattaatgt attcacaata aatagccgac aacctatgtc gctttttgat ttatgaagaa
       61 cgtatagtag actgaatctg aaatagtacg aaacaattgc taaaacactt atagaaatta
      121 attttacttt cccaatcgat ttgttctcat cttatttcaa tctgctatag aattcaatac
      181 gaggatcaat aaaagactac catttggaaa acagtagtcc ttattgttta ttttgaattt
      241 acataggcat ctacagcgat aatagcttga gcaacatctg aaggcgaaat cttaaacggc
      301 atctgatgaa ttgtctcacc ctccatagtt gcttgtttac caacttttat taaatcatca
      361 tatccaactt gatccaaatg catttctttt atagttgttg gcataccaat ttttttgtaa
      421 aactcaatat acttatcaag ttcttcttta ggtctatttt ccaataatag ttgtactaaa
      481 gttccataag ctactttttc accatgtgtt aaatgatgaa tgtcacctat caatgcagta
      541 aaaccattat gaattgcatg cgccgcagct aatcctccac tttcaaaacc tagaccactc
      601 aataaagtat tagcttcaac aatattttct aatgctggtg tcaccacttt agcttcacaa
      661 gctgccatag cctgtaaacc atctgcaaac agcgtttctt cacatttctt cgcaattgca
      721 actccagcca atgtttgctg ttgtcccaac atagtttttc catttgcctg cataaccgca
      781 cgcgcctcaa cccaagttgc taaaccatct gcaataccag acgctaataa acgcttaggg
      841 gcttgtgaaa taacttttgt atcaaccaaa actaaatctg gatttttaga ataaaataga
      901 taatgatcaa atgcaccttc atctgtataa ataacagata aagcagatac aggtgcgtcg
      961 gtcgatgcaa ttgttggagc aataataaca ggcttttcaa tcaaatctgc aatagctttt
     1021 gcgctatcaa tcgtctttcc cccaccaaga ccgataatac tatcacaatt ttctttctca
     1081 gccaaggcaa caactcgatt gatttcattg tcagaagctt caccattaaa tagcgccaga
     1141 acaatatgga aaccatacct atgtagataa tcttcaaatc gttttccaac aatatcataa
     1201 accaactgat cgcataatag aatagggcaa tttcccaaat ccaaaattga tttggcattt
     1261 tcaaacaagg cattttcccc ctgaatatat ctagaaggac tagcaaaaat tctcatatgt
     1321 atttcctctc tatctaaatg gaacgactat tttgaataac aaaccaatcg tcagaaaaat
     1381 catcaaccgc cttttggata gatggcatgg cgaaagctga ttcaaaaaca tccgctcctg
     1441 ctgtaacagc atgcgcacct gcagctaaag cattatttac ttgtgctaca tttttaaagg
     1501 atgcagctaa aatcttacta ggagagttct gtctatcaat agcaagagct aattgacgaa
     1561 tgacagaatt tgaatcaatg ttcagatttt ccattctatt ataatatgga gctaggtaat
     1621 ccgctcctgc ttcgatagct aataatccct gaataactgt ataaatagct gttgcagtga
     1681 tatggtagcc ctcttttttt agcgccttta ttgcacgtaa tccagctgga gtaacaggta
     1741 ctttgataaa tatatcatct cctgcttgtc ttcgaatttt atgagcatcc tttaagatgc
     1801 cttcaaaatc ttgagaaatc acctgaacat gaatagaggg tgtagagcca atcaattctc
     1861 ttacatcttt gattcgttca aaaaaattaa tagaaccctc tctttttgca atagtgggat
     1921 ttgaagttac cccagctagc ggcaaaattt cagaccactt tttaatctca tctaaattta
     1981 atgtgtcaag cataaattcc ataaaaagaa cctctttatt ttacaaagta tgctcagtac
     2041 gtcctataat gtcatcttgg gttgccttag aaagaacatt gaagaatgca gagtatcctg
     2101 caacacgaac aattaagtct ctgtgttttt caggatgttt ctgagcgtca atcagcgtct
     2161 ctctggaaac aacattgtat tgaatatggt acccatgtaa acgattaaag aatgttcgta
     2221 acaaagcaat tagttttaat ttatcttctt ctttggctaa cgtttgagga tttactttct
     2281 gatttaagag aaccccacct acgatttcat ctgttggtaa ttttgaaaca gattttaaaa
     2341 cagatgtagg gccatgttga tccatattat gtgatggtga acaaccctct gctaacggtg
     2401 tacccgcgtt gcgtccatct ggagttgcta atgttccacg tccctgccct acgttggctg
     2461 agatagaaga tgttcctgaa taacgaattc ctccaattgg acctcttcca taacgtgtat
     2521 taggatattt agcaatttca tcaacataaa tgtcataagc agcagtaacc aatttgtcag
     2581 cataatcatc atcattacca tacttaggtg catcatgaat caacatttct tgaatgacct
     2641 taccttcttc tccggcataa tctgtttcca gtgcatgcca aagctgactt gggcttatac
     2701 gttcttcctc aaacaccaat tttttaattg cagctaatga atccgacaaa tttgcaattc
     2761 caacttgcaa tcctgatata taatcatata ctgctccacc ttctttaagg tgttttccac
     2821 gaccaataca atcatcagtc aatgctgaac atagaatatc aggaacttct cgttccaatg
     2881 ataaatcaat agaattttca acaataacac tcattcgtgt caaatatctt agtgttttat
     2941 cccaagcatt ttctaattca gaaaagttct tcatatcctt aaaatgacca aagcttggtg
     3001 caaaccgttt acccgaagcc ggatcaattc catcattcat cgtgataagt agaaccttag
     3061 ggaagttcat ataactcata cctgtgcaac gatagcccca tttccctgga actgccgttt
     3121 caacacatcc aatggcactg taatcataag catcatcttc caatactcct tttgcaataa
     3181 aagaaggaat aataatctca tcattattaa atgcaggcat accaaaacca agtttcatca
     3241 cttcaataca ctcattcatg aaacgagcat ctaaacctgc atggtaacgt acagttagat
     3301 taggttgcgg tagatgggtt tgtgcaactg attttaatac caaataagat aatgggttaa
     3361 cagcatcctt cttatctcga gtctgtccac caattgtaac attttgatat aaaggacttc
     3421 ctgctgaaga aaatgtatgt gattgactgc gaaccttatt aattgtaatt gtcttaatcc
     3481 aaagatttgt cagacgttca acaatgctat cttctgtttc tttaccactt tctaaatcag
     3541 ccttcatata tggatacata tattgatcaa aacggccata tgaaagagag tggccattag
     3601 attcaatttg taaaatacat tgaataaacc aaactgattg aatagcttct gcaaaagtag
     3661 ttaccggttc atatgggact ctagagcaaa tatctgcaat ctcaagtaat tctttcttac
     3721 gtttaggatt tgcattttcg gctaaacttt tagcaagagc aacaaagcgc tttgcatata
     3781 ctttaatagc atcgattacg ataaatatag agtcgtaaaa atgatattta tcaatacttg
     3841 ctggatctgt taaatctaga gctgcttttg ctttacgagc ccgctcttca aaacctctta
     3901 agccaaattg caaaagtttc tgatagttaa ctgctaggtg agcatctcca gaattcatct
     3961 taccttccat accgaagaat cctgtttcca tataaacaga cacttcttca ggtaataagg
     4021 caccagctct agcacgtaaa ttattatttt cccaaaacgg agcaatactt ctaagttgtt
     4081 cttttgtttc ttctgtaata tagaaaacat ctccatcacg cttttcaaaa agatccaact
     4141 cattgagaac aaattctagc gtatattccg gaaaaatagg agcatcttta ttggaagaag
     4201 cttgatttcc cccaatcata gattcttctt caatatagat agtcatattt tccaaaattt
     4261 ctttcagcat atatgcacgt tttaggacat taggttgttc cttgtatcgt tcataggcgc
     4321 gtgttgctag aactgctctc tcagcatcaa tataaggttt tttatttaaa acatcttctc
     4381 gatatttgtt catcctttca gtaaggctgc caaaatattc tgtcttgatt gttgttcttg
     4441 ctacttctgt atttaccatc gtaaccacct ttctttcgaa aatattttta tttctttcga
     4501 aaatataata ccgattttta tagaaatttt caagctttta actagaaaaa ttttaactct
     4561 ctaattttta gcacaaatgt gtgagtttaa cagtaacaca caaatacctc taagattgtt
     4621 tgatttcatt ttggtaagct aaacgatcct gtactttaaa gaatggaaaa taaaccaatg
     4681 tagacatcgc taatatcacc agctgagtaa taactccttg ccatccaccc accaaaaatc
     4741 ctgataaaat agctggtgta ctccaaggca atgttacccc tgagaatggc tgcatgaaac
     4801 ctgttgcaat agctccatat actatcacag ctgcaagtac aggaacaaga atgaaaggta
     4861 caaacataac tggattcatg acaatcggaa atccaaatac aactggctca tttacgttaa
     4921 atattgctgg aaaagcggca acttttccta aggcttggta ttgttttgat tttgctgcaa
     4981 aaagcatggc aactacaaga ccaaacgtaa tccctgaacc tgatagaatt aaaaatgaat
     5041 ctaaaaattg ttgagtaaca atatgtgcac cattttctaa tgatagatta ccagaggcta
     5101 acatagcttt attagcatca agattagata aaagcagagc tgtcactact ccatttacta
     5161 ccgattgtcc atgaacacca aaccaccaca aaaatgatat aaagaatgca attccaatag
     5221 caccatacaa agatccagtt aaaccttgca atggaacttg aatagcagaa taaatcattt
     5281 ctatgaatgt tccgccatta gtcaatgact tcgctaaaat atatacaatc atagaaagta
     5341 agaaaattac aaatgctgga atcattgctt caaactgttt ggcaatagct tgtggaactt
     5401 gttctggcat cttaataaca atttttctct ttataaagaa ggtataaata cttcctacta
     5461 ccaaacctat aatgatagca ccgataattc cttgacctcc aaaccaaact ttactaatag
     5521 catccccaat tgcctcacct tgtttaggga tataagatga tcttagcaaa ataaagaatg
     5581 cagatacaga tagaactcca gctggtaaag cctctactcc gctattctta gcataagaat
     5641 aggcaattga aaaacaagaa attagaccca taatagcaaa agttcctgaa tatacttgca
     5701 taaacggctc tgtccaatta gctccaaaaa cactagcaat gctcttattt aatccttcga
     5761 acggcaattg tcccataatc aagaataaac taccaactac tgtcaatggc aaaattgcta
     5821 acatcccatc ttttagagct ataatgccac gcatattcac aaacttcatc atcggtgcaa
     5881 tgattttctg aacatccatc tttgccataa taaatctcct tttcttaccc actaatcaaa
     5941 gatagggcca aatctaatac ttttttccca tctaacatac catagtccat catcggaata
     6001 acagctatcg gaacatcaca cttatcacaa atttcttttg atttatctaa tgtataagca
     6061 acttgtggac ccaatagtgc aacatctata tttggcgcat aatccgctaa tttagactga
     6121 gaaaacgcct ctatttctgc ctcaactcca ctagcttgcg ctgcaatttt catattattt
     6181 acaagcatac cagtagaaaa acctgctgca caaaacaaac caatcttcac cattatgttt
     6241 tcctcctcta tgttaataac aatgataata ctctagtatt attttttatg aagttctttt
     6301 ctcaaactaa taatttcttt gattaaatta atctccgtca tactagtcat gagatgatct
     6361 tgtgaatgaa caaagagagc tgtaatttct gtctttgtac cagacgcttc ctgtgccaag
     6421 aattttgttt gtagattatg agcttctaat aaggctgcat cagctaactg gatttcttct
     6481 tcacatcgtt cacatgtacc attttttatg taatctaacg ctttataaat atgttgtttc
     6541 gcatcgccag catataaaat taaacccatg ataatttgat ctggaacaat aatttccata
     6601 aattcctcct catttcacta tgtaaaaagc ttttttcatt tgaaatttta aaattttctt
     6661 ttgtaactat agaatacaac tacataataa agttgtcaat ccaaaaacaa cagataaact
     6721 atttttgttt atataagcac aaatgtgcaa tcaactaaaa agaaaaacga taaactgaat
     6781 cagtctatca ttttcactca cctagaatct ctctaaaagt caaatcccca tcttcttcca
     6841 aaacttttaa aattgtattt ttgtctgtaa tcaaatgatt tactaaatta gcacgcaaga
     6901 cagaaagaat cgaagatact ttcgtatcac cgtaagcaac agctaaactt tgaggaatat
     6961 tttttaaatc ttccaaagag attgctatcg ttctttcctg taagttttca tagacttctt
     7021 taccttttga atcaaaaaat cgacaacaaa tttctcctac agttttaact ttggtcaatt
     7081 ctttaaagtc atcctctgta agcatgtcta accattgatg ttttccttta ttgctaaaat
     7141 caccaattcc gactacagct atatctaaat ctttccaact atttttcaaa ttttcaaaat
     7201 atcttgattg caaaatacca tctgctaaca atttattttc ttgcacaatc gttgcattca
     7261 taaatgtaca ctctccatga aattttctag acatttcata aatcagtgta ttcacatggt
     7321 atttagcgtg tatgtgacta ggaccacctg ctagaggata gaagtgaaca tttcggacac
     7381 ttttactgtg aattaaatct actaaattac ttaaactttt cccccaagaa aagccaattt
     7441 tcatattatc atcaattaaa ttcctaagga cacctgctgc aacttgagaa attctttcag
     7501 ataaaattgt tggattatca tcaaattcat ttggaataat ttctaaactt tccagaccat
     7561 atttttcttt tacataattt tccaacttaa acatatttgt atcaaaattc tctatttcaa
     7621 ttttaacaat tcctgcattc cttgcttctg ttaacattct actaatagag gttctataaa
     7681 ttcctaattt tgctgctatt tgtgactgat ttaagttttc aatataatac agataagcaa
     7741 ttttagagag cagtttattc ctatcttgat tcatacactt aacctcttac gaaactacct
     7801 taaccattat cccagcattt tctaatgtag ctatattttg tttagaaagt ttttcgtctg
     7861 ttattacttc atagacttga cttaaagcaa atcttcttac tgtacccctt ttatcaaatt
     7921 tacttgagtc agttagtaca atgactttat ccgacgctgc tgaaatatat tgaactacct
     7981 cactgcgcat taaatctttt cctgtaaagc ccatctcttt atcgtaacca tctgtcccaa
     8041 caaaagcttg atgcacatga aaagtctgta tcatttcttt taataaaggt cccacagtaa
     8101 cctgtgaatc cttctgaaac tctccaccaa gaacaataat acgacatgaa tcataagctc
     8161 tcacaaaatt tgctataaaa aatgaatttg ttacaatcgt aacatttctt ttttgcttgc
     8221 aaatttcctc agcaagtaaa gcacaggtcg atccagattc tatcattatt gtttcattat
     8281 ctgacaccaa ttttactgct tcctgaacaa tttttctctt aatttcataa ttaattgaca
     8341 aacgtacatt taagtcatct ccactattta atacagcata tccatgctct ctgtgtaata
     8401 aaccttttga ctctaattta tctaaatctt ttctaatcgt tactttcgat acatttaatt
     8461 tttccgataa tgtattaacg tcgatctttt catattctga tactaattta ataatttgtt
     8521 ccaatctttt cattttacac ctccgtttta ttctaccaaa ataaaaagca aaaaacaaca
     8581 aatcaacctt tcgttcgtaa ttgtttttct ttcgtttttg tgataggata gacttatgaa
     8641 gaggaggaac tcttatggaa atatctaaag gaattatttt taatattcaa cacttttcaa
     8701 ttcatgacgg cccgggtatt cgtacaactg tttttttaaa aggatgtcct ctgcgctgtc
     8761 catggtgttc taatcctgaa tctcaaagaa tgaaacctga aaaaatgaaa gatgctcaac
     8821 gagagaaatt caccttagtc ggtgaagaaa agactgtaga agaaattatt acagaggtat
     8881 taaaagacaa agaattttac gaagaatccg gtggaggttt aactttatca ggaggtgaaa
     8941 tatttgctca gtttgaattt gctaaagcca tcttaaaatc agctaaagaa catcacatac
     9001 acactgccat tgaaactact gcctttgttg atcatgaaaa atttatcgat ttaattcaat
     9061 atgtggattt tatctacaca gacctaaaac attataattc tataaaacat aaaaaagtga
     9121 ctggggtttt taatcaaatg attattaaaa acattcatta tgctttttct caaaataaaa
     9181 ctatcgtttt aagaatccca gttattccta attttaacaa tagtttagag gatgcagaaa
     9241 aattcgctac tctatttaac tcattaaata tcgaccaagt tcaactactc ccttttcatc
     9301 aatttggtga aaacaaatat cgtttattaa atcggaaata tgaaatggat ggagtcaacg
     9361 cacttcatcc tgaagatctt attgattatc aaaaggtatt tctgaaccac catattaatt
     9421 gttatttcta gttcatttcc ttgaaatgct ctagctattt gcagataaca agcatctata
     9481 taaggttatc aaagaagact tccccatgac tctaaatgaa tatatcttac aatatcgcct
     9541 gaaacaagct atagataaga tggctgaatc tcccaactcc cctttaagcg ctatctctga
     9601 ccaagttgga ttttcagact ataaatattt tgccaaagta tttaaaaagt atctccatat
     9661 ttccccaaag aaattgaaat cactcggaag aatagtaaaa taggctattc ttctttttgt
     9721 agagaatttt actctaatat agtgaattga aataagatgt gaacatctct atcaggaaag
     9781 tcaaattaat ttatagaaat attttagcag tcaaagtgta ctgttataga ttcaatacac
     9841 tatagaatag aattgtaggt tttaaaaacg cttacattgt tttaaaataa acttaaataa
     9901 cacaacggag atatcccatc atgaaaaaga aatggatgta ttatgctgct tgttcttcta
     9961 atgaatctgc cgatgacagt tcatctgata aaggagacgg tggttcgcta gtcgtttatt
    10021 gaccaaactc agaggactta attggagcaa ctattcctgc ctttgaagaa aaatatggta
    10081 tcaaagtaga actgattcaa gctggtactg gagaactttt caaaaaacta gagtcagaaa
    10141 aagaagttcc tgtagctgat gttatctttg gtggttctta tacacaatat gctacccacg
    10201 gagaactctt tgaaaactat acttcaaaag aaaatgataa tgttatcaaa gaatatcaaa
    10261 acacaactgg cttctctact ccttatacac tagatggtag tgttttaatc gtccaccctg
    10321 atttaactaa aggcatgaac atcgaaggat atagcgacct tctcaaacct gaactaaaag
    10381 gaaaaatcgc aactgctgac ccagcaaact cttctagcgc ctttgctcaa ttaacaaata
    10441 tgctacaagc tcaaggtggt tacaaagatg ataaggcttg gtcttatgta aaagatcttt
    10501 tcacacttat tgatggtata gtaaaatgaa ataagaacag gacaaattaa tcaggacagt
    10561 caaatcgatt tctaacaatg ttttagaagt agatgtgtac tattctagtt tcaatatact
    10621 ataaaatcgg tttaagttca tctggtgtct ataaagcagt cgctgatgga gaaatgactg
    10681 ttggtctctc ttatgaagat ccagcagtta aactcttaaa tgacggagct aacattaagg
    10741 tagtctatcc aaaagaagga accgtcttcc tacctgctag tgctgctatc gttaaaaaat
    10801 ctaaaaatat ggaaaatgcc aagaaattta tcgattttat tatctctcaa gaagtacaag
    10861 atacacttgg tacaaccact actaaccgtc ctgttcgtaa aaatgctaaa acaagcgaaa
    10921 acatgaaacc aattgacaaa atcaaaacac tcactgaaga ttatgattat gtcatcaaga
    10981 ataaatcaga tatcgttaag aaatacaacg aagtctttac agatatccaa tctaaacagt
    11041 aaaagaggtt cactatgagt gagatcgaaa ttattaacgc caaaaaaatc taccacgatg
    11101 tctctgttat tgagaatttg aacattacaa ttccaaaagg aagtctcttt acccttcttg
    11161 gagcttcagg atgtgggaaa acgacccttc ttcgtatgat tgcaggtttc aacagtatca
    11221 aagatggaga attttacttc gatgatacaa aaatcaataa tatggaaccc agcaaacgca
    11281 atatcgggat ggttttccaa aactacgcta ttttcccaca tttgactgtc cgagacaacg
    11341 ttgcttttgg tcttatgcaa aagaaggttc caaaagaaga attgattcaa cagaccaaca
    11401 agtatcttga actcatgcaa attgctcaat atgcggatcg aaagcccgat aaactcagtg
    11461 gtggacaaca acaacgtgtc accttggcat gcgccttagc ggttaatcta agtgttctcc
    11521 tcatggacga gccacttagt aatctggagg ccaaacttcg cttggatatg cgtcaagcca
    11581 tccgagaaat ccaacacgaa gtgggaatta caactgttta tgtaacccac gaccaagaag
    11641 aagccatggc tatttcagac caaattgctg ttatgaaaga tggggtgatc caacaaatcg
    11701 gccgaccaaa agaactctat cataaaccag ctaatgagtt tgtggcaacc tttatcggac
    11761 gcacaaatat tatccctgcc aatcttgaaa aacggagcga cggcgcttat atcgtctttt
    11821 cagatggcta tgcccttcga atgctagctc ttgatcaggt tgaggagcaa gctattcatg
    11881 taagcattcg tcccgaagag tttatcaaag atgaatctgg agatattgaa ggaactatta
    11941 gcgatagcgt ctatcttgga ctaaatacgg agtatttcat tgagacaggt tttgcctcaa
    12001 aaattcaagt tagtgaagaa tcaacttttg aagaagatct acaaaaaggc aatcgtattc
    12061 gtctacgaat caatacgcaa aaattaaaca tcttttctgc agatggttcc caaaacctga
    12121 taaaaggagt caaccatgga acgtaaaaaa ctaaatattt ggacagcctc ctctttcttc
    12181 atctttctta cctatcttgt ctttctcgtt tatcctatcg ttaccgtgct caagtaagca
    12241 cttatacatg aaggacaatt ctcactagct aattttgtca ctttctttag taaagtctac
    12301 tactctgaga cactagtcaa cagtttcaag gtttccatta ccgctactgt cacttcctta
    12361 gttgtaggaa ccctattagc ttatctcttc tctatgtatg acttcaaggg ggagaaattt
    12421 ctacaaatat tgattatcat tgcttccatg tcagctcctt tcgtaggagc ctactcctgg
    12481 gttctcttgc taggacgaaa tggggtcatc actaaatttt tgacaaatgc ccttcatctt
    12541 ccagctatcg atatttatgg attcaaagga attgtacttg tctttacact gcaactattc
    12601 ccactggtat ttctatatgt tgctggaaca atgaacagta ttgacaattc tctacttgaa
    12661 gcagctgaaa gcatggggtc cttcggattt aagcgtatcg taacggttgt tttacctctc
    12721 ctagttccaa ccttactagc agttccttgc ttgtatttat gagagcattc tcagactttg
    12781 gaacgcctat gttgattggc gaaggatatc ggactttccc tgtcctgatt tatacccaat
    12841 ttattagcga ggttggagga aattctgctt ttgcaattat ggcgattatc attgccttgg
    12901 cgattttcct tatccaaaaa cacattgcaa accgctacag tttcagcatg aatctgctcc
    12961 atccaattga gcctaaaaaa actacaaaag gaaaaatagc tgccatttat gcaacagtct
    13021 acggaattat ctttatctct gttttacctc aaatctactt aatttatacc tctttcctaa
    13081 aaacatcagg tatggtatct gttaaaggtt attctccaaa cagttacaag gtagctttcc
    13141 atcgtatggg atctgctatt ttcaatacca ttcgtatccc tttgattgcc ttagttctag
    13201 ttgttctatt tgcgacattt atctcctacc tagccgttag aaaacggaat ttgtttacaa
    13261 acttaattga cagcctcagt atggtacctt atattgtacc aggaaccgtt ctagggattg
    13321 ccttcatttc ttccttcaat actggtctat ttggaagtgg atttcttatg attacaggga
    13381 ctgctttcat cttgattatg tctctatctg tcagaagatt accttatact attcgctcat
    13441 ctgttgctag cttacaacaa atagcaccaa gtattgaaga agctgctgaa agcttaggaa
    13501 gtagtcgtct caataccttt gctaagatta caactccaat gatgctatct ggtatcattt
    13561 ctggagccat cttatcttgg gtcacaatga tttcaaaact ctctacttct atcctcctct
    13621 acaatgtcaa aacaagaaca atgactgtag ctatttatac agaggttctc agaggaaatt
    13681 acggtgtagc cgcagccttg tcaactatcc tgactgttct aacagtaggt tccttgctct
    13741 tgtttatgaa aatctctaaa agcaatagca ttacacttta gttttccaca tcaaaaacag
    13801 ccgaaaggag taccctcggc tgttttttct tatcttgata ttcttatcaa atccctagct
    13861 catggcaagc aagtctagac tgattaaata gagccttctt ccatcttctc acgtcctagc
    13921 tctcggtaac tacggtcacc gacaacttca accctaaact gaccgtcctc atattcaaga
    13981 atcgtcacgc taccattatc tagaccatgc ggatgcatgc cattaatcag ataaacaatg
    14041 gttccaatag tcattccatg gctgacaaca agggcgttac ctccaccttg atcttccatt
    14101 tcttttgcaa tcatttcaaa gccttccttg attcggccac tgagtttttc ccagccttca
    14161 gcccaaccag ctgtatcgac ctctaccaag ccctcagcca gttcagcata agacaattgg
    14221 tgaacgtggt ccacattaaa gatacgagga ataatgccca tgaaaagatc gccatcatag
    14281 gctccatcaa aactaccgaa acaccattct ctgatacgct tgtccatgcg ataagggatt
    14341 ttcccctgca agccaagttc ttcaaggata attcccatgg tctgaatggt acgaccagaa
    14401 tcactcgaat aagcgcgctc aaactgtaga tcagattctc gcaaaccgat tcctaactct
    14461 tgaatccctc gttcaccttc agcagttaag ggagtatcgc tccaaccttg cgcgcgacca
    14521 atcgtgttaa acatggtctt gccatgacgt accaaataca atcgtacttt taccattttc
    14581 cgtcctccgt ttgcttctat tatatcatga atgataaaat aaaagccacc catacaggcg
    14641 acttttgaag gagattatta tgaaaaagtt taggagttca ttaaataaag atattagatg
    14701 aaaatcaaat tcaaactaat tcagtgttat ctgtttcaaa taatattagg aggtctttat
    14761 ttaatgatta tagtatacac gtctaatctt aaatagaact taaaatttct cctattttct
    14821 taatttttaa aactatgaat tggtgctggg atttgtccac cgcgagagat gaagtcgaca
    14881 gacgaagccc cattaacctt cataacaggt gcagttccta atagaccacc aaactcaatc
    14941 atatcgcctt ctcttccttt gggaatgata cgaacagctg ttgttttcat gttgataaca
    15001 ccgattgctg cttcatccgc aatcatagcc gcaatggttt cagcaggcgt atcttctggg
    15061 atggcaatca tatccaatcc aacagaacag atagccgtca tagcttctag tttttctaaa
    15121 ttaagagagc cattttgcac tgcagcaatc attccttcat cctcagaaac agggataaag
    15181 gcaccagata aaccaccgac ttggttgcag gccatcactc cacccttttt aacttggtcg
    15241 ttcaagaggg ccaaggcagc cgtcgttcca tgcgtgccaa ctgtttctag ccccatttcc
    15301 tcaaggacac gtgccacaga gtctccaacc gcaggggttg gtgccaaact caagtccaca
    15361 ataccaaact ccacacccag tctctcactg gccatttgac caaccaattg accgatacga
    15421 gtgattttaa aggcagtttt cttaactgtt tcggctacta catcaaagct ctgtccacga
    15481 actttttcca aagcacgttt cacaacacca ggaccagaaa ctccgacatt gatgataaca
    15541 tctgcttccc caacaccatg aaaggcaccc gccataaatg gattgtcctc aacagcatta
    15601 gcgaatacaa ccaacttggc cactcccata tctgaaagat ttgctgtttc cttgataatt
    15661 cgtcccatat ctgccacagc cgtcatatta ataccagact tggttgagcc gatattgact
    15721 gacgagcaga ccttatccgt ctcagccaaa gcgcgaggaa tggaattgat gagaatctca
    15781 tctccctttt gataaccttt ttgtactaag gcagaaaaac caccaataaa gtccacacca
    15841 atctctttcg cagccttatc aagcgctttt gccagaacca cgtagtccgt cgcatctgtc
    15901 gctgccccaa tcagagaaat aggtgtcacc gatacacgct tattaacgat aggaattccc
    15961 aactcagccg caatttcatc accaacagct actaaattag ccgcctttgt cgtaattttt
    16021 tgatagattt tctccgcagc acgattgata tttggatcga tacagtccaa aagagaaatc
    16081 cccatggtaa tggttctaat atcgaagttt tgctcctcaa tcatggcgat ggtttcagta
    16141 acttgtctaa tatccatgat gacctcctag atattataca tagcttcgaa aatcgctgca
    16201 ctctgaatat tgatttttac attcaaagtt tgcccaaaag cttcaaattc attacgaaga
    16261 taggtaaaat cttgcttttc atcactagat acaacagcca tcatcgtaaa atattcatcc
    16321 aagacagttt gagagatatc gtcaatattc aatcctaatt ctgcaatttt accagaaaca
    16381 cctgcaacaa ttccagattt atctttacca acaacagtta taatggcttt cataagtaaa
    16441 ctccaattct tcttaaaata agaaacctta acattaaaca ggattctttt caaatagtat
    16501 agcataattc taacgaaaat actcaaaaac gcctgcttac gaagttgttc ttaagaaaaa
    16561 aacaatttcg taaacaagcg tctactatcc caacttatga tgagtgttcc cgctaggacc
    16621 gaaatcctag cggtagacca gagctagact aagagcacaa gactccatca tcataacact
    16681 caacaaaatt gatgatttta tactaattcg atgatcgcca ttggcgctgc atcaccacga
    16741 cgtggttcag ttttaaggat acgagtgtat ccaccgttac gttcagcata acgaggtgcg
    16801 atttctgaga acaatttttg aagtgctgta gtagaagtgt acttatcagt tgcttcatca
    16861 tagttttcag atgcgatttc attacgtacg aaagcagctg cttgacgacg tgcatgcaaa
    16921 tcaccacgtt tacctagagt aatcattttt tcaacagttt tacggatttc tttagcacga
    16981 gcttcagttg tcacgattga ttcgttgatc aaaaggtcag ttgtcaaatc gcgaagcatt
    17041 gctttacgtt gtgagctagt gcgtcctagt ttacggtaag ccatgtattc ctcctttatt
    17101 tatcttttaa tccaagaccc aaatcaatga gtttgagttt cacttcttcc aaactcttgc
    17161 gtccaagatt tcgtactttc atcatctctg cttcagattt ttctgtcaaa tcatgcacag
    17221 tattgatacc ggcacgtttt aaacagttgt atgaacgcac agacaaatcc agttcctcaa
    17281 tcgtacgatc taaaatacgg tcgtcagatt cagtatcagc ttctttcatc acttcagttg
    17341 acttagcaat ctcagtaaga tttgtaaaca aatcaagatg ttctgtcaaa atacgtgctg
    17401 aaagccctaa agcatcttct ggaataattg ttccatttgt caagatttca agggttaatt
    17461 tgtcgaaacc atcattgcta cctacacgag caggttccac ttgatagttg acttttgtaa
    17521 ctggtgtata aatagaatct acagcaagtg ttccaactgg tgcattatcc tttttatttt
    17581 catcagcagg tacatatcca cgaccactgt taacagtcat agtcgctttt agagaagaac
    17641 cttcaccaat tgtaaagaga taatgatctg gatttacaat ttcaatatcg ctatctgtca
    17701 aaatgtcacc agctgttact tcagcaggac cttcaacatc cagttcgatg attttttcgt
    17761 cttcaacgta cgatttcact gcaattcctt taatgttcag aatgatttgc atcacgtctt
    17821 cacgaacacc tggaactgtg tcaaactcat gtaacacacc atcaatgttg atagatgtca
    17881 cagctgctcc tggtagagaa gctagaagta cacgacgaag agagttacca agagttgtac
    17941 cgtagccacg ttcaagtggt tcgattacaa acttgccata atctttattt tcatcaattt
    18001 ttgttatatt tggtttttca aactcgatca tttagttact ccctcttaaa cgaaaagcag
    18061 tgtaatgcga tgattataca cggcgacgtt ttggaggacg agcaccattg tgtggcactg
    18121 gagtcacatc acgaattgct gttacttcaa gaccagcggc agcaagcgca cgaatagctg
    18181 actcacgacc agaacctgga ccttttacag taacttcaac tgatttaaga ccgtgttctt
    18241 gtgcagattt agcagcagct tcagaagcca tttgagcagc gaatggtgta gatttacgag
    18301 aacctttgaa accaagagca ccagctgatg accaagcaat tgcattacca tgcacatcag
    18361 taatcataac aatagtgtta ttaaatgtag cgtgaatatg agcaatacca gattcgatat
    18421 tctttttcac acgacgttta cgtgttggtt tagccaagac ttttacctcc tatattattt
    18481 tttcttacca gcaatcgcaa cagctttacc tttacgagtg cgagcgttgt ttttagtgtt
    18541 ttgtccacgg acaggaagtc cacgacggtg acggatacca cggtatgaac cgatttccat
    18601 caaacgtttg atgttcaagt ttacttcacg acgaaggtca ccttcaactt tgattgcatc
    18661 cacttcacga cggatagcat cttcttgatc tgatgtaaga tcacgtacac gaacatcttc
    18721 tgagattcca gcagcagcca aaattttctt agatgttgca agtccgatac cataaacata
    18781 agtcaatgag attactacgc gtttgtcatt tggaatatca actccagcaa tacgagccat
    18841 gttttctcct ttctatctta tccttgacgt tgtttgtgtt ttggatttgc tgggcaaatt
    18901 accataacac gaccattacg acgaataact ttacagtatt cgcaaattgg tttgaccgat
    18961 ggtcttactt tcatttctta tccctccaag tttttcgatt atttaaagcg gtaagtgata
    19021 cgtccacgtg tcaagtcata tggactcatt tcgacagtaa cacgatctcc cgctaaaata
    19081 cgaatatagt ttttacgaat tttaccagaa actgttgcta aaatctgatg tccattttca
    19141 agttcaaccg taaacattgc attcggcatt gtatcaacta ctttgccttc aacttcaatc
    19201 acatcgtctt ttgccacgca aaagcacctc cataaatttc gattcgatgc ctctagacac
    19261 agagacaaca attataagtc agactatctc agtataacat ttgtagcgga ttttggcaag
    19321 tgtgaaaaac gctttatttc aaatttgtca atactttttc aatatctgag aagacatcat
    19381 tgatatcttg attaccttcg atgtcatgaa ccaaaccttt ggcacggtag tgagcaatga
    19441 ttggttctcc ttgagcaata ttaacatcca aacgacgttt tactgtctca ggcttatcat
    19501 cttcacgttg gtagtaatct tcttctttat agtcaactgg tgggttaaag accttgtgga
    19561 aagtttctcc agttacgcgg tggatgatac ggccactcaa acgttccaaa aggctgtcag
    19621 ggttcacttc aatattgata acaccttcta gttcaatgcc aagttcagtc aatgttttgt
    19681 ccaaggcatg agcttgttca attgtacgtg ggtaaccatc caataagaat cctgtttctt
    19741 taatatcatc ttgtgaaaga cgttctttta cgattccatt tgtaacttcg tcaggaacca
    19801 attcaccctt gtcaatatat gacttagcaa gaacacccat ttcagtttga tttgccattg
    19861 cagcgcggaa catatcacct gttgagatat gtgcaacatg gaattgttct acgatttttg
    19921 ctgcttgagt tcccttacct gcaccaggta agcccataat caaaagattc atgatttgat
    19981 ctccttattt tatttttaaa tagaagcaaa aagtcttttc acccctattt aaaaacaaaa
    20041 tagaagaggg gagatccaac tcttacaaat gtcagagttt aaacctccac tccctcagca
    20101 tttactgatt cagtaaatac ttttattctg ttctgtccat gaaaccaaca tacttacgtt
    20161 tcaataggta accttccaat tgcttgattc cttcgatacc tgtagagata atgatcaaga
    20221 gacttgttcc accaaaggca acaacatcag aaagaccaaa tacatcttta gctgcaatcg
    20281 gtaaaatgga aatcacacca aggaagaggg aaccaacagt tgcaagacga cgaagaagtt
    20341 tagacatata ttcttctgta cctttaccag gacgaactcc atggatatag gcaccactct
    20401 tttgtaggct ctctgctgct ttttcaggat taatctgtac aaacgtatag aagaatgtaa
    20461 agagaataat caacaaagca tacatggcaa taccagttgg agaagtagtt gccagcatct
    20521 cttgtgctac ccttacccaa gcccaatcat gacctgtggc actcaaaaac tgaagaatag
    20581 ccgcaggcgc tgcagtaatc gaactggcaa agataacagg gataactcca gcagggttta
    20641 cctttaacgg aaggtaagag ctagatggag caccttgtgc aaccttagta tattggattg
    20701 gaattttgta ttctgcttgt tgaacataag ttgtaaagta aataatcaac aatacagtaa
    20761 taatcaaaat gattacgaaa atgatagatg aagtgatacg gctacttggg acgttcacaa
    20821 agtagtccac atagatgccc tgaatcatct ctggaattga ggaaacaatc ccggcaaaga
    20881 taatcatgga aacaccgttt ccgtatccct tatctgtaat ttgctcaccc aaccaagtga
    20941 caatcatact accagctgtt aagatgatac caatcgtcag aaaaacttgt ggagttaaag
    21001 cagttttaat caattgagct ccagccaagg tattaaaacc agctgtaatc ccgatagatt
    21061 gcacaaaagc gagaactaga gcaatataac gagtagcttg attcaatttt cttcgaccta
    21121 cttccccttg tttaccccac tctacaaact tgggtaaaat atccatttgc aagagttgga
    21181 caacaataga agcggtgata tagggactaa ctcctagggc aaaaatcgaa aagtttttta
    21241 gggcattccc cgacaccaag ctcaacatgt ttaagaagga taatccactt aaagcattca
    21301 agctattggc attcacacca ggaactgtaa tgctagttcc gatacgaaag accaaaacga
    21361 taaaaattgt aaataaaatt tttgatcgaa cctgcttgac tttaagagct tctcttaata
    21421 atttaaaaaa cataggtcac ctctcttaga tgacttctac tgaaccacct ttagcagtga
    21481 tagcttcttc agctgattta gagaatttag ctgctttcac agtcaatttc ttagtcaact
    21541 caccgttacc aagaatttta atacctgact tttcagcttt aacaattcct gcttcgataa
    21601 gaacaactgg agttacttca gcaccatctt caaagacgtt caattggtca aggttcacaa
    21661 ttgcgtattc tttagcgttg atgttagtga atccacgttt tggaagacga cggaacaatg
    21721 gagtttgtcc accttcaaaa ccaaggcgaa ctccgccacc gctacgagct ttttgacctt
    21781 tttgaccacg accagatgtt ttaccgttac ctgatgaagt accacgacca acgcggttac
    21841 gtactttacg agaaccttct gcaggtttca attcatgaag tttcattttt attttctcct
    21901 cttttgtaaa atgctagcgc cgataaggga gaaaaggttg tctcccccat caactcgcct
    21961 atacgatgtc atcatagatg actatatcta gttttagggg atggtacagt gcacatcccc
    22021 taaaacttca ttagtttact tcttcaactg ttactaagtg agatactgct gtaatcatac
    22081 cacggatagc agcgttatct tctttaataa cagagctgtt caatttgcca agtccaagtg
    22141 ctacaacagt tttacgttgt gatggaatgc gtccgattgg agacttagtc aaagtaattt
    22201 taatttgagc cattttatcc cctttcttat gccaaatcag aaactgaaat accacgaagg
    22261 gcagcaattt cttcagcgcg tttcaattgt ttcaaacctt caacagttgc acgaacaatg
    22321 ttgattggag tgttagaacc aagtgattta gatgtaatat ctgccacacc tgccaattcc
    22381 acaacggcac gaactgcacc accagcggca actccagaac cttctacagc aggtttcaac
    22441 aatactttag ctccaccgaa ttctgaaaga acttcgtgtg ggattgttgt tccaaccata
    22501 ggaacttcga tcaagttttt cttagcatca tctactgctt tacggattgc ttctggaact
    22561 tcttgagctt taccagtacc aaatcctacg cgaccattgt ggtcaccaac aacaacaaga
    22621 gctgcgaaac gaagacgacg tccaccttta acaacttttg taacacggtt gacagcaact
    22681 acgcgttctt ctaattcaac tgcattgtct ttaaatgcca ttttctagtg tcctcctatt
    22741 agaatttcaa tccgttttca cgagctgcat cagccaaagc tttcacacgt ccgtgatata
    22801 gatatccacc gcggtcgaac accacttctg aaataccttt agcgtttgca cgttctgcaa
    22861 cgagtttacc gacagcaacg gcttgttcag ttttagttcc ttttgaaact tctttatcaa
    22921 gagttgaagc acttgcgagc gttacacccg ctacgtcatc aatcacttga gcgtagatgc
    22981 ctgtattaga acggaatacg ttcaaacgtg ggcgatcagc agttccagag agttttccgc
    23041 gaacgcgacg gtggcgtttt tggcggagtt tgtttttatc tggttttgaa atcacagttt
    23101 tcacctcttt agttttaaat cgtgtgctat gcacaaagtt ggaaaatagg ttggtggttg
    23161 atgatcaacc actcaacatt atttacctgt tttaccttct ttacggcgaa cgaattcacc
    23221 aacgtaacgg atacctttac ctttatatgg ttctggtgaa cgaaggctac gtacgtaagc
    23281 agctgtttga ccaactactt cttttgaaat tccgctaaca acgattgttg ttgggtttgg
    23341 aagttcaaaa gtaattcctt ctggagcttc aacttcgtct ggatgagatt taccaacagc
    23401 caaaacaagt ttagatcctt gaagctgtgc acggtaacca accccacgca tttcaagttc
    23461 tttcttgaat ccttctgata caccaacaac catgttgttc aaaagggcac gagtagttcc
    23521 gtggatagtt ttcatttctt ttgaatcgtt tggacggtga agagttattt cagtaccttc
    23581 cacacggatt tcaatatctt ttgagaactc acgagtaagt tctcctttag gtccttttac
    23641 agttacaacg ttgtcattgt tagcgagttc aacaccagca ggcaacacga taactttatt
    23701 accaatacgt gacatgttta ttttctcctg ttaaattgtc aggccagaac ggccagtttt
    23761 cacggggttc agatacttat ttagttcaag agctgaactg aacacgctct aagaactgtg
    23821 caaaatagat aagttggctt gtttgtaaac aaacttctcc aacttcctaa ttttgctttg
    23881 ttctttacga gctttgtatc ttgattttac caaacgtaag cgataacctc accaccaaca
    23941 ttcttttggc gtgcttcttt atcagtaagc aaaccttcag aagttgaaag gatggcaatt
    24001 ccaagtccgt taagaacttt tggaaggtct tcacgttttt tgtagacacg aagtcctggt
    24061 ttagaaacac gtttcaagtt agtgataact ttctcaccat ttggtccgta tttaagaaat
    24121 acacggatga cgccttgttt gtcatcttca atgatttcaa cgttttttac aaaaccttcg
    24181 cgtttaagga tttcagcaat cccttttttg atgtttgatg caggtacttc aagtacttcg
    24241 tgtttagctt ggttagcatt acgaatacga gttaggaagt ctgcgattgg gtcagtcata
    24301 accattttgt ttttctcctc ttactagtag tttgcaagtt gcacttgcta gttaatacat
    24361 gatacaaaga gcgtaacagc acgagcaaaa atagacaatt taatgcagaa gcaatgctcc
    24421 aaagcaaatt agtctttttt gccaaagctg tagctcgtgt tcaaattggc aagcccaatt
    24481 gaacccgggc taaactctgt gtgaaaaaga taaactttcc tagaaacttt agtttcttcg
    24541 tcaagtttcc tatttttact tggagttttg acgctcttga tatcttaaat taccaagatg
    24601 cttttgttac accaggaatt tgacctttat gcgcaagttc gcgaaaagcg atacgactca
    24661 gaccaaattt gcggtaaact gaatgtgggc gccccgtaac cctacaacga ttatgtaaac
    24721 gagtcggtga ggcgttgcga ggtaatttag ataaaccttc gtagtcccct gccgccttta
    24781 atgcagcacg tttttcagca taacggtcaa caattttttg gcgtttagcc tctctagcta
    24841 ccattgattt tttagccatt agatttacct cctatattat tttgcaaaag gcattccaag
    24901 gcctgtaagc aatgcacgtg actcttcgtc agtgttagca gttgttacga taacgatgtc
    24961 aagaccacga gttttgtcaa cgtcatcgaa gttgatttct gggaagatta attgttcttt
    25021 cacaccaagt gtgtagttcc cgcgtccatc aaatgatttt gttgggacac cgtggaagtc
    25081 acgtacacgt ggaagtgaaa ctgataccaa tttatccaag aattcgtaca tacgttcacc
    25141 acgaagggta acttttgcac cgatcgcaac accttcacga agacggaagc cggcgattga
    25201 ttttttagct ttagtgataa gtggtttttg acctgagata agtgccaatt cttcagcagc
    25261 tttttcaagg cttttagcgt ttgatacagc ttcaccaaca cccatgttca aaacaatctt
    25321 atctacttta ggcacagcca tcactgatga gtagttgaat tgttctgtca aagcaggaac
    25381 tacttcatta agatattttt cttttaaacg atttgccatt atacttctcc tttccttcgt
    25441 gattaatcaa gcacttcgcc tgattttttg ttgtagcgaa cttttttacc gtctacaaat
    25501 ttgtaaccaa cacgaccagc tacaccattt ttgtccaaaa cttgaacatt tgatacgtgg
    25561 atagctgctt ctttctcgat gataccacct tgaggaagct cgttagttgg acgttggtgt
    25621 ttcttaacaa tgttaacacc ttcaacgata actttgttta cttttggaag ggcagtaagg
    25681 acaacagctt ctgttccctt atctttacca gcgattacgc gaactttgtc gccttttttt
    25741 acaaacatta ggtttctcct tgatttttct tacgcccata agggcaccct agcttgaagc
    25801 taggggacta gtttgttcct aaaaattaaa gtacttctgg agcaagtgac acgatcttca
    25861 tgaaaccacc ttcacgcaat tcacgtgcaa ctgggccaaa gatacgtgtt ccgcgaggag
    25921 ttttgtcttc acggatgata actgctgcgt tttcgtcaaa tttgatgtat gaaccatcag
    25981 cacgacgagc acctgattta gtacgaacga taactgcttt aacaacgtca ccttttttaa
    26041 ccgcaccacc aggagtagct tgttttacag atgccacgat aacatcaccg atgtttgcaa
    26101 atttacgtcc tgaaccacca agaactttga tagtcaagat ttcgcgagca ccgctgttgt
    26161 ctgcgacttt caaacgagtt tctgtttgaa tcatttcagt tttctccttt caggtttgat
    26221 tagatgatga ccgcttcttc aacaacttct acaagacgga aacgttttgt agctgaaagc
    26281 gggcgagttt ccatgatacg tacgatatcg ccttctttgg caacattgtt ttcatcatga
    26341 gctttgtatt ttttagagta gttaatacgt ttaccataga ctgggtggtt acgttttgtt
    26401 tcaactacaa ctgtgattgt cttgtccatt ttgtcagata caacacgtcc aacaagaact
    26461 ttacgattat tgcgttccat tgaaatttct ccttccctag tctattattt cgcttcagat
    26521 tgaactgttt tgatacgagc gatttgtttt ttaacttctt tcaagcgagc tgtttgttcc
    26581 aattgaccag tagcagcttg gaaacgaagt tcaaacaatt cttttttcaa ttcgttttcg
    26641 cgcttcgcga gttcttcttg agaaagacca cgaagttctt taacaaattc ttttacttca
    26701 ttaagtttca tgccttctcc ttattctgct tcacgtttta cgaatttaca tttaactggc
    26761 aatttgtggc tagcaagtcg aagcgcttca cgtgcaatct cttcagatac accagcgatt
    26821 tcgaacatca ctttaccacg tttaactggt gctacccaac cttcaggtgc ccctttacca
    26881 gatcccatac gcacaccgat agctttagca gtgtatgatt tgtgtgggaa gattttaatc
    26941 caaactttac caccacgttt catgtaacga gtcatggcga tacgagcagc ttcgatttgg
    27001 cggttagtga tccagtggct agttgtagct tgaagaccgt attcaccgaa tgctacttct
    27061 tttccacctt ttgcttcacc gcgcattttt ccacggaact cacgacggtg tttaacacgt
    27121 ttaggtacta acattggtta tttacctcct ttagtgtttt tacgagctgg aagaacttca
    27181 ccacggtaga tccatacttt aacaccaagt ttaccgtatg tagtatctgc ttcttcccaa
    27241 gcgtaatcga tatctgcacg aagtgtgtga agcggaacag ttccttcaga gtatccttca
    27301 gcacgggcga tatctgcacc gttcaaacga cctgatactt gagttttgat tcctttagct
    27361 ccagcacgca ttgcacgttg gattgcttgt ttttgtgcac gacggaaagc aacacgttgc
    27421 tccaattgac gagcaattcc ttcacctaca aggtgagcat ccaaatcagg ttgtttgatt
    27481 tcgatgatgt tgatgtgtac ttgttttcca gtcaatttgt taagttttgc acggagtgca
    27541 tcaacgttag caccaccttt accgataacc atacctggtt tagcagtgtg aagtgaaacg
    27601 ttaactttgt ttactgcgcg ttcgatttca atagttgaaa ctgctgcgtc agcaagttct
    27661 ttttgaacga atttacggat tgcaagatct tcatgaaggt aatccgcgta ttctttttca
    27721 gcataccatt tggcatccca atcacggatg atgccgacac gcataccaat tggatgtact
    27781 ttttgaccca cgattttacc tccttatttt tctgcaacag ctacagtgat gtgagctgta
    27841 cgtttgttga ttggtgaagc tgaacctttc gcacgtggac ggaaacgttt catagttggt
    27901 ccttcgtttg cgaatgcttc agatactacc aagttagctt tatccaaacc aaagttgttt
    27961 tcagcgttag ctacagctga gttcaaaact ttcaagatga tttcagcagc tttgtttgga
    28021 gtgaatgtca agattgcgat tgcatcggct acgcttttac cacggatgtt atcaagaaca
    28081 agacgtgatt tacgaggtga aacacgtact gtacgagcca ttgctttagc tgaagtaatt
    28141 tctgccattt atgttctcct tattttctac gtgttttctt gtcgtctgca gcgtgacctt
    28201 tgtaagtacg agttggtgca aattcaccaa gtttgtggcc taccatgtct tcttggatgt
    28261 aaacaggtac gtgtttacgt ccgtcataaa ctgcaatagt gtaaccaatg aaacttggga
    28321 agatcgttga acgacgtgac caagttttaa taactttttt cttttcgtcg ttagcttgag
    28381 cttcaacttt tttcatcaaa tgctcatcga cgaaaggtcc ttttttaaga ctgcgtccca
    28441 tttttatatt ttctccttta aatgttgtac cacagcggct tgcactccta tggagcgcta
    28501 ccgagctggc ggatttacta gttgcttaag cgactagttt aatattattt ctcgttgcga
    28561 cgacgaacga taagtttgtc agatttcgct ttcttgttac gagttttaag accaagagca
    28621 ggtttgcccc atggagtaga tggtgcttta cgaccaactg gtgctttacc ttcaccacca
    28681 ccgtgtgggt gatcgttagg gttcattaca gaaccacgaa ctgttgggcg gatacctttc
    28741 caacggctac gtcctgcttt accaaggttt acaagtccat gttgttcgtt tccgacaaca
    28801 ccaactgtag cacggcaagt tccaagaatc atacgaactt cacctgattg aagacgaaca
    28861 agaacatatt taccttcaga acccaatact tgagcagatg caccagcagc acgtaccaat
    28921 tcaccaccac gacctggttt caactcgatg ttgtgaatca aagtaccaac tgggatgtta
    28981 gcaagtggaa gagcgtttcc gactttgata tctgcttctg gacctgaaac gatacgttga
    29041 cctacttcaa gaccttttgg agcgatgatg tatgctttca caccgtcagt gtagtgtaca
    29101 agagcgatgt ttgcagaacg gtttggatcg tactcgattg ttttaacaac tgcttcaacg
    29161 ttgtctttat tacgtttgaa gtcaaccaaa cggtagaaac gtttgtgtcc accaccttgg
    29221 tgacgaactg tgatacgacc gttgttgtta cgaccagcct tgctcttcaa tgcaacaagc
    29281 aatgattttt caggagtgct tgttgtgatt tcagcgaaat ccaaagaagt catattacgg
    29341 cgaccgtttg ttgttggttt ataaacacga attcccacga tatttcctcc ttagattatt
    29401 cagcttcagc agcaaacaac tcgattgctt tagaatcagc tgtaagtgtg atgatagctt
    29461 ttttagtttt gttagtaaaa ccagtgtaac gtccaacacg tttagctttt ggttttacgt
    29521 tgattgtgtt aacattggca actttaacac cttcgaaagc agcttcaaca gcttgcttga
    29581 tcaaaagttt gtgtgcacga gtgtcaactt caaatacata tttccctgct tcaagttgag
    29641 ccattgagct ttcagtgatg acaggttttt tgataacatc atacaaattc attatgcaag
    29701 aacctcctcg attttagaga tagctgcttg tgtgacaaga agtttgtcgc tatttgcgat
    29761 gtcaagaaca cttgcagttg tagcagttgc aactttcacg tttggaaggt tacgagctga
    29821 aagagctgcg aattcatttc cttcttcaag gataacaaga actttagaat cgatgctcaa
    29881 tgctgcaaga acttttgcaa attcagcagt ttttggagct gtaaatgaaa gagcgtctac
    29941 agctacgaat ttgttttcag caactttttc agagtaaact aatttaagag ctaggcgacg
    30001 aactttttgt ggaagtttgt agccgtatga acgtggagtt ggtccgaaga caacaccacc
    30061 accacgccat tgtggtgagc ggatagaacc ttgacgagca cgtccagttc ctttttgacg
    30121 ccatggtttg cgtccaccac ctgatactgc agagcggttt ttaacagcgt gtgttccttg
    30181 acgaaggctt gcgcgttggc tgatgattac atcaaacaca actgattcat ttggttcgat
    30241 accaaatact gcatcgttaa gaacaacttg gccagcttct ttaccagttt ggtcaaataa
    30301 tgttacgttt gccattgtga ctgatttccc ctttctttat tatttaccag ctttaactgc
    30361 tgatttgata gtgataagag atttcttagc acctggtacg ttacctttga taaggataac
    30421 gttcttttct ggaacaactt gtacaacttc aaggttttga attgttacgc ggtcgccacc
    30481 catacgtcct gcaaggtttt tacctttgaa tacgcggtta ggtgcaacag gccccataga
    30541 acctggacga cggtggtaac gagaaccgtg agccattggt ccacgtgatt gtccgtggcg
    30601 tttgataaca ccttggaaac ctttaccttt agaagtacca gttacatcaa caacatctcc
    30661 agctgcgaat gtttcaactg tgatttcagc gccaacttcc aagccttcaa cgtttttgaa
    30721 ttcacgaatg aagcgcttag gagccgtgtt agctttcgct acatgtcctt tagcaggttt
    30781 gttgctcaat acttcgcgtt tgtcatcgaa accaacttgg atagcgttgt atccgtctgt
    30841 ttcaacagtt ttaacttgaa gaacaacgtt tggagttgct tcaataactg ttacagggat
    30901 caattcgcca gcttcagtga agatttgagt cattcccact tttttcccta agattccttt
    30961 tgtcatgaga aaatagttcc ttttctatat tttttattca aaaagttttt aacgagcgtt
    31021 ttttatgctc aagtctaaga tacaaagggc gtcaaactca aagtgaaaat aggaaactaa
    31081 cgcagtgtct agcggacaat aggaagttta tctttttcac accgagttta gcccgtgttc
    31141 aattagattg aaacaccagc ctctgctctt ttatatttta gattaaagtt tgatttctac
    31201 gtttacacca cttggaagat ccaatttcat caaggcatca actgtttttt gagttgggtt
    31261 aacgatatcg atcaaacgtt tgtgtgtacg catttcaaat tgttcgcgag agtctttgta
    31321 tttgtgagtc gcacgaatga ttgtgtagag gctacgttca gttggaagtg ggattggacc
    31381 cgcaacttgt gcacctgtac gagtagctga ttctacgatt tttgcagccg ctgtgtcaag
    31441 cgtacggtgt tcgtaagctt tcaaacggat acggattttt ttgtttgcca tctttttctc
    31501 cttttcgtct atttaagata ataggctagc tccacaagaa aaccgacgcg gtgttgcgtg
    31561 gcaatgcaac cgagcgtgtc gcaacctctt gcatcaaaac taaggctgta atttacagca
    31621 ccataataga ataacacaaa tcccctgcga ttgcaaggga tttgttaggt tttttcgttt
    31681 ttttgggatg aaactgtttt cctacttttt ctttctaaaa ttagggattt tcttctatat
    31741 ttcttctata cataagttaa gtcctcttga catcaaattt atcttctgat tggtccacta
    31801 agatatccgc cttagactca gtttctttat agtatcgcag atactgctcc cgtctcatct
    31861 gatggctagc caatataaag gatgcatagc gatttctcac agtcgtatct ctagcaaggc
    31921 gtcgctttaa ttcggtctcc tcatccgtgt agaaacagat ggttttttca aagagttcct
    31981 tgggtagaaa accaacagac atcccttcga caatcaaaat tggtttggct ccagacaaga
    32041 cctcactagc cttccaaggt tcttcaattg tcaagacatc catacccgcc tgcaaggcaa
    32101 ggatatctct ctgcaaactc tccagttcat gcgccactgg cagactggct gtcacctttt
    32161 gattcggcgc gtccttgggt actaccaaat agcgtccgga ggtgatatag ggatctgttt
    32221 ctagcaaatt ta
//
LOCUS       DAVHKZ010000024        31991 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000024 DAVHKZ010000000
VERSION     DAVHKZ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31991
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.024"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(25..1452)
                     /locus_tag="VVO74_001330"
     CDS             complement(25..1452)
                     /locus_tag="VVO74_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU5695346.1"
                     /translation="MKTTNKVAIYVRVSTTSQVEEGYSIDEQKDKLEAYCKIKDWKIY
                     DVYVDGGFSGANTQRPELERLISDVKRKKVDIVLVYKLDRLSRSQKDTLFLIEDVFAK
                     NDVAFISLQENFDTSTPFGKASIGMLSVFAQLEREQIKERMMLGKEGRAKNGKSMSWT
                     TIPFGYDYSKETGVLSVNPTQALIVNRIFTEYLNGKPVVKIIRDLNAEGHVGRKRPWG
                     ETITKYLLKNETYLGKVKYKDKVYEGQHEPIITQELFDLVQLEVERRQISAYEKYNNP
                     RPFRAKYMLSGLMKCGYCGASLGLRYTRKDKNGISHHKYQCRNRHSKDLEKRCESGWY
                     SKEELERGVIKELERIKFDPKYKNETLAKKEETIKVEEIKKQLERINNQVSKLTELYL
                     DEIITRKELDEKNDKIKTERQFLEEQLENQKSNVLSIRKRKLTRLLKDFDVEKLSYED
                     ASKIVKNIIKEIIVTKDGMSITLDF"
     gene            complement(1620..1820)
                     /locus_tag="VVO74_001331"
     CDS             complement(1620..1820)
                     /locus_tag="VVO74_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695347.1"
                     /translation="MSNESRPMEVIKHNLDCKCHRRREWIRVNDKWHAIEFSVDDPNE
                     PPMTEEEKANVALILQQHLSKE"
     gene            complement(1822..2613)
                     /locus_tag="VVO74_001332"
     CDS             complement(1822..2613)
                     /locus_tag="VVO74_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HEU5695348.1"
                     /translation="MARGRGKLTPQDKEDMKVFSANLNSILSDRNCKQAELSRATGIP
                     PSTLTGYVKGTSLPIPGNVQKIADFFGVPKSVLDPRFITNNFMVNDSSSNTPQIQTIY
                     DELEPPRQGKVLNYAKRQLKEQKNEEETKINEVSEAIRLYSYDYYDHPASAGTGQYLN
                     DVRVERIELPVDVDADFVIPIKGDSMEPDYHDGDLVFIQTSVDLNDGVIGVFNYNGDA
                     YIKQLVIDEDQAYLHSLNPEYKDMPITPDTDFRIIGEVVDLYREK"
     gene            2786..3061
                     /locus_tag="VVO74_001333"
     CDS             2786..3061
                     /locus_tag="VVO74_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015973618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695349.1"
                     /translation="MNTLNEKAINIFKAVAKETLIQGTYEENFLYSQLEAFCTNCRQF
                     AFGWTELAEEIERQERYLLDSGFTQEEIDDIRFDAAFAGMLDKLNVA"
     gene            3136..3303
                     /locus_tag="VVO74_001334"
     CDS             3136..3303
                     /locus_tag="VVO74_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001005822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695350.1"
                     /translation="MNESFLTILGISMIASFITNLIAYLAGKHHLKKKIKNHKMWFDS
                     EIERIKKKYHL"
     gene            complement(3294..3743)
                     /locus_tag="VVO74_001335"
     CDS             complement(3294..3743)
                     /locus_tag="VVO74_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695351.1"
                     /translation="MNNFSFIETLAIAAIPAFVSGMWSYIAAKGNSKHEIDKINIAHS
                     QELENVENQFKQDMEKMQKQHSQELYSLQQTHELRLLELEKVSQLDTQTDQGLKINDL
                     IFKAISGEISADVAIKNMSTLSHFANKQQPSDLQKQFVKKLSKKNHK"
     gene            3942..4112
                     /locus_tag="VVO74_001336"
     CDS             3942..4112
                     /locus_tag="VVO74_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695352.1"
                     /translation="MKEKLNEFLKFRSQFTKREWFEINQAVEACLNEKADQLKLDDSD
                     VEIISKRLGRSI"
     gene            complement(4337..4543)
                     /locus_tag="VVO74_001337"
     CDS             complement(4337..4543)
                     /locus_tag="VVO74_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695353.1"
                     /translation="MTDYQLEASLIVLGKEFDRTKKNGKESFSVHVSFFDGLDANQHL
                     QEFARQYPVKIDRSNSDQITFLIK"
     gene            4616..4843
                     /locus_tag="VVO74_001338"
     CDS             4616..4843
                     /locus_tag="VVO74_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5695354.1"
                     /translation="MPKMTLRAIRTNYNLSAKEVADKLNIHQQTLLKYEHDSSKIPMD
                     LLDKLARLYNVEKDFIFLGKKYELNHNLGEV"
     gene            4886..5248
                     /locus_tag="VVO74_001339"
     CDS             4886..5248
                     /locus_tag="VVO74_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU5695355.1"
                     /translation="MQYIIRNTHGNYTSLNNAYAQDKRLKATTIGILTVILMNKSDWV
                     VYPDEIARRLGISRRTVDEHFKLLEKAGYLRVYRLGLGRGKGVTVYRFFSDMPISDDY
                     FEYLKTNLEKELSTDNGV"
     gene            complement(5658..5849)
                     /locus_tag="VVO74_001340"
     CDS             complement(5658..5849)
                     /locus_tag="VVO74_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695356.1"
                     /translation="MKSFKDFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTIELLEKYHEWLHS"
     gene            5968..6111
                     /locus_tag="VVO74_001341"
     CDS             5968..6111
                     /locus_tag="VVO74_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695357.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     KTV"
     gene            6178..6975
                     /locus_tag="VVO74_001342"
     CDS             6178..6975
                     /locus_tag="VVO74_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001056933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEU5695358.1"
                     /translation="MNMNLNTNEILTTTEYDMFRKISNRKITENPKLEEELLSEGQRQ
                     PILVNEKMEVIDGQHRLYYLRKHRKPVRYIIDPTANFKTVISMNTSAVNWALQDYVYS
                     FALEGDPEFVKLAKFLDENELLSDKMVIVAGSGRRDGTAAHVVKKLKKGDYVFSNEKQ
                     LREFCKFYERVLNETKLPNKPFLQSVLWTLYTTSVFDENRMLTQLKKSDLTSEDIEGF
                     AKKKLLLTFLELYNGRWSDDHPSLIQYFINRKGSLTIPSLPKQDEDN"
     gene            6993..7130
                     /locus_tag="VVO74_001343"
     CDS             6993..7130
                     /locus_tag="VVO74_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695359.1"
                     /translation="MKVTVYVYGRKLEPDEPIIIPENHRFYDIWNGIVNEMLDNEEDV
                     A"
     gene            7130..7351
                     /locus_tag="VVO74_001344"
     CDS             7130..7351
                     /locus_tag="VVO74_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695360.1"
                     /translation="MKLLTKLKLRLEGVLKSVNLDWREVAVELMNDLFEERKRRFAFE
                     QENYDLKQELAAYKYKENFDIKARLQGEM"
     gene            7352..7606
                     /locus_tag="VVO74_001345"
     CDS             7352..7606
                     /locus_tag="VVO74_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695361.1"
                     /translation="MYIISIYVKNTETGNEDFSLIGRDFLPTGHQDYIARVFGTKEEA
                     IDYLKSISYIASGVHGNDWVYQNEKLPEIESRCRIWKVGE"
     gene            7619..7879
                     /locus_tag="VVO74_001346"
     CDS             7619..7879
                     /locus_tag="VVO74_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695362.1"
                     /translation="MFKALKTIKKIKQLQKEMHAFSLAFLALQDMGLMPETERSKAKA
                     QTMHDVSRVLKDVLDGKSVDEAIKRLNSEVKAEEVGQKDDQN"
     gene            8149..8967
                     /gene="bet"
                     /locus_tag="VVO74_001347"
     CDS             8149..8967
                     /gene="bet"
                     /locus_tag="VVO74_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HEU5695363.1"
                     /translation="MTNNQIVEAKGDFLTNPQLLNSGIIRKYLDPQGKASDEELAYFI
                     AQAKAQNLNPFTKEIYFIKYGTQPAQIVTAKSAFEKKADSHPQFDGKEAGVIYLMDGE
                     IKYSKGAFIPKGAEILGGWAKVYRKDRTYPTETEVSFEEYDNSKIRARVKELTQQGKD
                     VTYPVMNSYGKPIGENNWDTMPCVMIRKVALVSAYREAFPAELGASYEADEIQLDNTP
                     KDVTPQESREDVVARKMAQIDQFNKEQEANHADPEPAKTEEPIQGELLDGELEY"
     gene            8977..10041
                     /locus_tag="VVO74_001348"
     CDS             8977..10041
                     /locus_tag="VVO74_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001157031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEU5695364.1"
                     /translation="MQELQVIDDKKINKIYEMITTDELTRESFEKDLIEATEKYKDYI
                     PTAGTLKDDKAKRAEFNKLIESKNRIRIDTKNLLSETANTWDSYAKSIIDPFATVVSE
                     FDKGIKEIEEHQRQLKIDTVKSYLANKSAEYMLDPRLFDEKALEYVKASDFMADGVTL
                     KKATMKSLDDMVTFEFQKQQEFEKAKSAISGLCAEYGMTDSPYIRQLKDLTLAEVFGQ
                     IKADYEFEKQKEELRQDLERAERSNQELLAAQQTKQQEQAPKSTETPNFDPETGKILD
                     GGQILQNEPNALRGAENDLKRYAQKMTLEVYFVDTAEKDRFKAGLSQLGFDFKKNYQV
                     RGYQRIDPLTQAELNEQCGW"
     gene            10209..10532
                     /locus_tag="VVO74_001349"
     CDS             10209..10532
                     /locus_tag="VVO74_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695365.1"
                     /translation="MDIRKISDSVAIYSDGKKLQVIHNLGDEFILDFKVGEDSVWNLN
                     GQVVEIIDMIEPVFKVFSFCSKSGEGMQRLKHAIVHFEKFEQYIRDNQEDLMIWWHNP
                     GGEYD"
     gene            10525..10860
                     /locus_tag="VVO74_001350"
     CDS             10525..10860
                     /locus_tag="VVO74_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein Cse60"
                     /protein_id="HEU5695366.1"
                     /translation="MIKTVFFSCDYPHHEVIDDQINSWLAENPGIKLIDIKFQSNVSA
                     VADSGVSAEYWHTSALIIYKVPSENNISSINSNGLGFIISCEKCGSLSIIKGKDVGQN
                     VCYECKGEK"
     gene            10955..11371
                     /gene="ssb"
                     /locus_tag="VVO74_001351"
     CDS             10955..11371
                     /gene="ssb"
                     /locus_tag="VVO74_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU5695367.1"
                     /translation="MINNVTLVGRLVAPPDLRKTPNNVSSLQGTLAVNRNFKNENGER
                     EADFINFQAWRGTADIIAQYCSKGSLIGIIGRLQVRSYEKDGQRRYVTEVIAESVALL
                     ESRNSQHGQGNSFQNGNSSPFTDPNPFDLPNDGLPF"
     gene            11384..11782
                     /locus_tag="VVO74_001352"
     CDS             11384..11782
                     /locus_tag="VVO74_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695368.1"
                     /translation="MEIDKIIKKDVLEFMETISDNKIDASKINVTERIAIIIEKQKIE
                     VVTTLNYDMSISFDNKDTAPTLDDNGDLFEPVYKCKVKAIPKNDVFFTSLTRVKSNTK
                     TLQEVKKFFEFVNENRENLFEMAGFKGVLE"
     gene            11779..12210
                     /locus_tag="VVO74_001353"
     CDS             11779..12210
                     /locus_tag="VVO74_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HEU5695369.1"
                     /translation="MKLTLNIEPKPQSRPRFARRGSFTTTYEDKDMKTWRNHCQLLIA
                     NQYMGQPILEGALRTRLRFYIKPPQYISKVKKNQQALLDEIIPVGKKPDIDNYEKALY
                     DSMSGIVFQDDGQIALHDVGKFYSLNPRIEVEIEVMKSLSI"
     gene            12226..12408
                     /locus_tag="VVO74_001354"
     CDS             12226..12408
                     /locus_tag="VVO74_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000796349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695370.1"
                     /translation="MADYALYQGDVFVTLGTLAQISSETGITERMLKYYTYTSHQRRH
                     PNGRAVIKIEEEDNEN"
     gene            12433..12750
                     /locus_tag="VVO74_001355"
     CDS             12433..12750
                     /locus_tag="VVO74_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695371.1"
                     /translation="MMEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPIDYDLGATKDWLPKSKEFDDWVGYSPSMAQVVIAVYLIY
                     RGN"
     gene            12752..13444
                     /locus_tag="VVO74_001356"
     CDS             12752..13444
                     /locus_tag="VVO74_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEU5695372.1"
                     /translation="MNKQELIKKLEERRTITGNFQGYVVWWKDVKEIFEQLDESEIGH
                     ADEAPRYVKNILARLRELPLHDREVWLKAIMSEFEQDFSRAKWREGYEQGKIEGMVER
                     EKVIVPQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLDGY
                     EVEKEKRYFVKIKGNIKENMLVYGELLKRYFFTKSFSLDDVIYSHTRKELEDAKFGWV
                     FDCPGIEIEEVE"
     gene            13444..13605
                     /locus_tag="VVO74_001357"
     CDS             13444..13605
                     /locus_tag="VVO74_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695373.1"
                     /translation="MSLTLNSTIGDLVLAIGEIIVGSDGKTTTAILEIPDQSFYLEIE
                     LKLKEEVIN"
     gene            13602..13862
                     /locus_tag="VVO74_001358"
     CDS             13602..13862
                     /locus_tag="VVO74_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HEU5695374.1"
                     /translation="MKRFIAIWILLSAGLNIWQMDRIRDLEEKKPMVIYKADNAGVEI
                     FGKVVEKGRHGKLYTLTIRDYGVFVVTKDVYDKVKVGDEVLL"
     gene            13859..14281
                     /locus_tag="VVO74_001359"
     CDS             13859..14281
                     /locus_tag="VVO74_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695375.1"
                     /translation="MTETIKLPDYYEPDWKNARYGSLEELKELLLFKRIVKWDKDFLL
                     LEDGTKVTIEMSESDCCASAGGEFQDVSLDAVITNIEIGEPEEIPDHWGTGYKNKVTI
                     FHNQNPVAIANCEAEHNGYYYSVCSLVIGDIHFPVVNA"
     gene            14293..14730
                     /locus_tag="VVO74_001360"
     CDS             14293..14730
                     /locus_tag="VVO74_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695376.1"
                     /translation="MTPRYRAWIKTEKRMFFSDDILAIDYENKEIVTQQVYFENGLPD
                     DRDIYCYDFDEIELMQSTGLKDKNGKEIFEGDIVRTTRFLGRADEIGGFYEYDKEFIG
                     IVKQLEGSWVIDTGSDAVCLWTEIEENEIIGNIYENKEFGGRK"
     gene            14727..15098
                     /locus_tag="VVO74_001361"
     CDS             14727..15098
                     /locus_tag="VVO74_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695377.1"
                     /translation="MRPCKYPYSGRRKKQETPSPIFSARPIFDEVPIVEEVKVEFGVE
                     ASMGRIYPETLIHLDISGYGNRVHSVHRFPGILLSVGESIQLKMLFYKRLRNFTTDRF
                     LTFRESDWKFFIRDLVNEFKH"
     gene            15171..15575
                     /locus_tag="VVO74_001362"
     CDS             15171..15575
                     /locus_tag="VVO74_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEU5695378.1"
                     /translation="MNKAKELLKELQDLDMDIQSRIDEINELEAGLLSSPKWSEVKVQ
                     GGQTRKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRMINRLKNPKYRAVLRMTYINK
                     GTADSVCYDLNMSRTTYYRLKNEAVLALEEVI"
     gene            15656..15738
                     /locus_tag="VVO74_001363"
     tRNA            15656..15738
                     /locus_tag="VVO74_001363"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15687..15689,aa:Tyr,seq:gta)
     gene            16005..16484
                     /locus_tag="VVO74_001364"
     CDS             16005..16484
                     /locus_tag="VVO74_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEU5695379.1"
                     /translation="MAFFDYSKGGDGKLSGLRIKQKRFADEYIISGNATEAYKKAGYR
                     VSSDRVAGVEGHKLLKNPKIKSYIDERLKQLDSEKIADQQEVLSYLTSVMRGETQEQT
                     LISIGELGQTITDIDVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDIPD"
     gene            16462..17760
                     /locus_tag="VVO74_001365"
     CDS             16462..17760
                     /locus_tag="VVO74_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEU5695380.1"
                     /translation="MSQTYQIKQNDIVVDLPKTVGAGYGQFWRSRNLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETSRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFDKDELLRDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAESRL
                     IEELRSEHGISRIKESRKGKDSIMAGVSKLQGYTIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            17772..19241
                     /locus_tag="VVO74_001366"
     CDS             17772..19241
                     /locus_tag="VVO74_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEU5695381.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHSTEGSHLKKLKSYYL
                     GEHAILEHTRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMAELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKHQAEVFTENLHYHMVLRSTDSGTIQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNKD
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRSVR"
     gene            19150..20787
                     /locus_tag="VVO74_001367"
     CDS             19150..20787
                     /locus_tag="VVO74_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEU5695382.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEV
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTGLAYG
                     FSGLPESEIKHLQSFSWVGDGSTYSTNIWKNTGKLTSSIKDELLISLMTGRDTRETAQ
                     AIAERFNVGQNDARRLVRTESAFFHNQMELLSYEEADIEKYIFAAVLDKRTSRICQEH
                     DNQVYDRDKAVPGVNCPPMHPWCRSTTVGYDEDADYSKLKRRARNPETGKTELVPADM
                     TYKEWYSKYVAKDGEKVYNQDTREAKAKFYSEQLLSKISGVEPKITSDMQRIAGENKL
                     AGLEFRKKTVESLSRKIIADSLVENISLSKAVSKINDALRYTTIFDSDTFTEEYLKMK
                     QKLIAEGYKIVKVKNTWPVDGPYKGVNTVVEKDGINFEMQYHTQESFDLKNGSLHELY
                     EKYRDTNTSDLERMKLFKEMLDLSNGLEIPKNIERVK"
     gene            20789..20998
                     /locus_tag="VVO74_001368"
     CDS             20789..20998
                     /locus_tag="VVO74_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695383.1"
                     /translation="MKDIKYYRTTTNNAQVLRLIDGVMQVFDIEKKWVNSMDWFNKIF
                     FNDFTDFEEISENDAFTYIDRMVAA"
     gene            20995..21408
                     /locus_tag="VVO74_001369"
     CDS             20995..21408
                     /locus_tag="VVO74_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU5695384.1"
                     /translation="MIDIALAIAKKAHAGQVDKAGVDYIQHPLYVASQVNTEQEKAVA
                     LLHDVIEDSDITAADLFASGLSNEVVTAVQILTKKKGQSYQEYLGKVKSNNLARVVKL
                     ADLKHNSDLSRLKSVTNTDYERVKKYKNAIYYLST"
     gene            21451..21738
                     /locus_tag="VVO74_001370"
     CDS             21451..21738
                     /locus_tag="VVO74_001370"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695385.1"
                     /translation="MNKYKKLIELIENNGLEIQSKKCYDPQSAWHGEELWIVDKKKQN
                     KIFDLSGNGYCFHDAKVEEAIEEVEKYLLLKKMDTFDDFKKWVEKNAKPKK"
     gene            22002..22526
                     /locus_tag="VVO74_001371"
     CDS             22002..22526
                     /locus_tag="VVO74_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEU5695386.1"
                     /translation="MSEEINATVSTESTETVDTQENVDTVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTSAETVSESITSIQKAWEESVQKGVSERMKGSAPIKNAQT
                     VQQEVTEKWRKDFL"
     gene            22549..23574
                     /locus_tag="VVO74_001372"
     CDS             22549..23574
                     /locus_tag="VVO74_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HEU5695387.1"
                     /translation="MAFEELNTAESRKKHLGIIEDVLAVNSYSTPLVTSSDAVTLQGR
                     SFTVATGNTTELKDYKRNKDNEFDHVEVEEKVYTLDEEKYWGRFVDQLDERDSNGQVN
                     INYVIARQAAEVVAPYLDELRFGAALGNVSDNVAMGKTAGANNAYNAVLDVSEKLDEL
                     GITKERLLFVTPSFYKAIKSEIVRLPHGDADKKVLGKGYVGELDDYTVYKVPSKFLKG
                     VNALATAPGVVTSPVQVDNTKYNDNIPGRFGELVEQLLYTGAFVLEHFKKYIITIADS
                     KPAAKPSTQGKVVNRAKAWKTGTTYKEGDTVTHADKVYVAVKDISNSSTAPDTDTTNW
                     KEKTGKK"
     gene            23584..23772
                     /locus_tag="VVO74_001373"
     CDS             23584..23772
                     /locus_tag="VVO74_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695388.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVA
                     ISDVLEEIFPKPEFLEED"
     gene            23774..24085
                     /locus_tag="VVO74_001374"
     CDS             23774..24085
                     /locus_tag="VVO74_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEU5695389.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGEHSRTEGGIAVVYGENGLSTDLLQRIRMHRLARVAGHVFEA
                     E"
     gene            24066..24404
                     /locus_tag="VVO74_001375"
     CDS             24066..24404
                     /locus_tag="VVO74_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695390.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            24379..24894
                     /locus_tag="VVO74_001376"
     CDS             24379..24894
                     /locus_tag="VVO74_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEU5695391.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDRAIGEVYTNLKYAPYVEFGTGPIGQANHSGISPEV
                     SVTYKSNPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            24891..25259
                     /locus_tag="VVO74_001377"
     CDS             24891..25259
                     /locus_tag="VVO74_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695392.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGIVDLHSELVFQFRMEN"
     gene            25262..25675
                     /locus_tag="VVO74_001378"
     CDS             25262..25675
                     /locus_tag="VVO74_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEU5695393.1"
                     /translation="MLANGITLSYGETKDSYTKLVGLKEVPEFGIELEKVENTTLEDT
                     VKKYEFGIGDIGELEYKFSYNNSSATAPYRVLRKAADDKKKLYFEQAYPDGTKVIFEG
                     QVSVKLGGGGVNAVIDFTLKIALQSNLTFTDGIGG"
     gene            25680..26060
                     /locus_tag="VVO74_001379"
     CDS             25680..26060
                     /locus_tag="VVO74_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695394.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSLEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVDK"
     gene            26099..26449
                     /locus_tag="VVO74_001380"
     CDS             26099..26449
                     /locus_tag="VVO74_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695395.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYR
                     LSQMISNHVSLLLSKDAKAFEFWEYAPELFVEEQQAVEQERQKQALLLHKERMREFAE
                     RHNRKRKEEVNGNS"
     gene            26436..30029
                     /locus_tag="VVO74_001381"
     CDS             26436..30029
                     /locus_tag="VVO74_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695396.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSSSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIESTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILEQATAKYGDTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIERIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANG
                     LGRQKERITRALVALFDNIGNISEAVGNIAQDFSSTFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVAPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPILALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFAETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICQAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIGNIFGNLGSWFGGRWNDSKNALAEANTWLGDKFKS
                     GRDKVNSAFEKVGSWFGDRWNDIKDGVKEADTWFGEKFESAKKKTQNPFQKIGSWFGD
                     RWKDMQDALKEIPNWFKNLFNDAMDNAKNIVKSGIDKLKSFFNFDWSLPKIKLPHFNI
                     SGSFSLMPPRIPSFSVDWYARGGVFNSPSIIGVGEAGQEAVMPLERNTGWISILAQKL
                     AERMPANNVPTGYSLPAGDIVIQIAGHEFGRVAIQEINKEHERAGQTLLKI"
     gene            30038..30388
                     /locus_tag="VVO74_001382"
     CDS             30038..30388
                     /locus_tag="VVO74_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695397.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSEFFEVSYPDPMDGQVTKTFYVGARTAPSYTFTEK
                     FKPWSGAKFNLVER"
     gene            30393..>31991
                     /locus_tag="VVO74_001383"
     CDS             30393..>31991
                     /locus_tag="VVO74_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEU5695398.1"
                     /translation="MDALTRRQFDRSMFAKERTLAIRVGEYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMTTGRSLELDNVFITQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFIFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGFEAKIQAQIEAADKDFDQKVDKIKKDFNDQVELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKEAKRKAEEALRNAGASSSLAQESKRIGLDSVARLEAFKSQ
                     TTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQVEALSRTKNELDGASTLLAQE
                     AKRIELDSVARLEAFKSQTTSAQTA"
BASE COUNT        10399 a         5554 c         7247 g         8791 t
ORIGIN      
        1 aaatacagaa atacgctaga ccctttaaaa atctagcgtt atcgacatgc cgtcttttgt
       61 aacaataatt tcttttatga tatttttgac aatttttgaa gcatcttcgt agcttaattt
      121 ttcaacatcg aagtccttta gtagccgtgt tagctttctc tttcggatgc tcagaacatt
      181 cgatttttga ttttcgagct gttcttccag gaattgcctt tctgttttga ttttatcatt
      241 tttctcgtcc aactctttcc gagtgatgat ttcgtccaag tacaattctg ttaattttga
      301 gacttgatta tttatccgtt cgagttgttt ctttatctcc tcgaccttga tagtctcttc
      361 tttcttagcg agtgtctcat ttttatattt tggatcaaat ttaattcttt caagttcctt
      421 gattacaccc ctttcaagtt cctctttaga gtaccaccct gattcgcatc ttttttctaa
      481 atctttgctg tgtcggttcc tgcattggta tttatgatga gagattccat tcttgtcttt
      541 tcttgtatat ctcagaccaa gtgaagcacc acaatatccg catttcatta atccagaaag
      601 catatacttt gccctgaacg gccttggatt gttatatttt tcataggctg aaatctgcct
      661 tctttcgact tcaagctgga ctaagtcaaa caattcttga gtgataattg gttcatgctg
      721 cccctcgtat accttatctt tgtactttac ttttcccaaa taggtttcat ttttcagcaa
      781 gtatttcgtg attgtttcgc cccaaggtct ttttcttcca acgtgacctt cagcatttaa
      841 gtctctgatg atcttgacta ctggcttacc gttcaagtat tccgtgaaaa tacggttgac
      901 aatgagcgct tgggtcggat tcactgataa gacgccagtt tcttttgagt aatcatagcc
      961 gaatggtatt gtcgtccatg acatggattt tccattcttt gcccgtcctt cttttcctaa
     1021 catcatacgc tctttaatct gctcacgctc cagctgagcg aatactgata gcataccgat
     1081 tgaagccttg ccgaaaggcg tagaagtgtc aaagttttct tgcaagctga taaatgccac
     1141 atcgttttta gcaaacacat cttcaatcag aaacagagta tctttctggc tacgactgag
     1201 gcggtctagc ttgtagacta gcactatatc gactttcttg cgcttcacgt ctgagattaa
     1261 acgctccaat tcaggtcttt gagtgttagc acctgagaaa ccaccatcaa cgtagacatc
     1321 gtagattttc cagtctttga ttttacagta ggcttcaagc ttgtctttct gctcatcgat
     1381 agagtaaccc tcttccacct gcgaagtagt ggacaccctg acgtagattg cgactttatt
     1441 cgttgttttc attgaatttg tacccctttt ttgataaaat aggtacaaga aaacgtctca
     1501 aaaggtaata tcttttgaaa agtttttctt gccactagcc tcacgctcgg agtcgccaaa
     1561 ctttgagagc gtggggcttt ttttgtttgc aattatttcc attttggaaa cagttggttt
     1621 tattctttcg ataagtgttg ttgaagaatt aaggccacgt tggctttctc ttcctctgtc
     1681 ataggaggtt cgtttggatc gtctaccgaa aactcgatag catgccattt atcatttact
     1741 ctaatccact ctcttcgtct gtggcatttg caatctaggt tgtgtttaat cacttccatc
     1801 ggtctacttt cgttactcat gttatttctc cctatacaaa tccacgactt cgccgataat
     1861 tcggaagtcg gtgtctggtg taattggcat atctttatat tcagggttta ggctatgtag
     1921 gtaagcctgg tcttcatcaa taacaagctg cttgatataa gcatcgccgt tgtagttgaa
     1981 tactccgata actccgtcat tcaaatctac acttgtctga atgaatacca ggtcaccatc
     2041 gtggtagtca ggctccatgg agtcaccttt gatggggatg acaaagtcag catcaacatc
     2101 tactggtaac tcaatccgtt ccactcgtac atcattcaaa tactggcctg tacctgcgga
     2161 agctgggtgg tcgtagtagt cgtaactgta gagccgaata gcttctgata cttcgtttat
     2221 cttcgtttct tcttcgtttt tttgctcttt cagttgcctc tttgcataat tcaggacttt
     2281 gccctgtcta ggtggttcta gttcgtcgta gatggtttga atttggggag tattagaaga
     2341 agagtcattg accatgaaat tattagttat aaatctagga tctaatacag atttaggaac
     2401 tccaaaaaaa tctgcaattt tttgaacatt accagggatt ggcaaagaag ttccttttac
     2461 ataccctgtc aatgtactag gcggtattcc tgttgctcga gacagctcag cttgtttaca
     2521 atttctatca gataaaattg agttaagatt tgcagaaaag actttcatat cctctttatc
     2581 ttgaggagtt aatttccctc gtcctcttgc catattttta cctcctatct tctttactat
     2641 ataataccgt ttattttcga ttttgtaaat aaaaaattcg aaaaaattac gaaaaaattc
     2701 gaaaaatcat tgacatacga tttaaatcgt agtataatat aatcaagctt aaggaaataa
     2761 caaaaacaaa ccggagggaa acaccatgaa cacattaaac gagaaagcaa tcaacatctt
     2821 taaagcagta gctaaggaaa ctttaatcca aggcacttac gaggaaaact tcctttacag
     2881 ccagcttgaa gcattctgta ctaactgccg tcaattcgct tttggatgga cagagttagc
     2941 agaggagatt gaacgtcaag agcgttacct tctcgattct ggtttcactc aagaggaaat
     3001 cgatgacatt cgttttgatg cagcatttgc aggaatgctt gataaattaa atgtagcctg
     3061 attggtatca ccaaggttcg aatccttggc aggttgttgc tcatagagcg aaaaaagaga
     3121 gaaaggagta gaacgatgaa tgaatctttt cttacgatac taggcatatc aatgattgct
     3181 agttttatca cgaatttaat tgcttactta gctggtaagc atcatctgaa aaagaaaatt
     3241 aaaaaccaca aaatgtggtt tgattctgag atagagcgta tcaagaaaaa gtatcatttg
     3301 tgatttttct tggataattt tttcacaaat tgtttttgaa gatcggaagg ttgttgcttg
     3361 ttcgcgaaat gactaagagt gctcatattt tttattgcta catctgcaga tatttctcct
     3421 gaaatagctt taaaaattag gtcatttatc tttaagcctt ggtcggtttg agtgtctagt
     3481 tgagatactt tttcaagttc aagtaatctt aattcgtgag tttgttgcag cgaataaagt
     3541 tcttgtgagt gttgcttttg cattttttcc atatcttgtt taaattgatt ttcgacattt
     3601 tcaagctctt gtgagtgtgc aatgttaatt ttatcaattt catgcttgct gtttccttta
     3661 gcagcgatgt aagaccacat gccagaaaca aaggcaggta tggcagcgat cgcaagtgtt
     3721 tctataaaac taaaattatt cataagattt ctccaatcat tttattttga ttataccaca
     3781 tttgaaaggt agttagaatt ggaagataaa atcattgaac ttgctgatta cttcatcagc
     3841 gaaaacacaa cgtacagaga agctaaaata gcgtgtgaga agctatttct tcaagtcagt
     3901 catgagatag aactcagggc aatggaaagt aggacgaggg tatgaaagaa aaactaaacg
     3961 aatttctaaa attcagaagc caatttacaa aacgagaatg gtttgaaatc aaccaagctg
     4021 tcgaagcttg tttaaatgaa aaagccgacc agttgaaact ggacgactca gatgtagaaa
     4081 tcatttctaa aagactagga cggtctatct aaagaaaggg tcaaacaaat ggcgtctaac
     4141 agaactatat cagtaaatac atcagagcat gatgtattgt tgacggcaag aaaaaaccac
     4201 cctgctgtat tcgtcgatgg aatgtttctc gacggagttg agcgagtgga atttaccaat
     4261 cattatctgg agaagtgtga agttgtttta acgtttaacg atagagttga aaccaatccc
     4321 ttccctctaa acgatattac tttattagaa aagttatttg gtcagagttc gaacggtcaa
     4381 tctttacggg atattgtcgt gcaaactctt gaagatgctg attagcatct aaaccatcaa
     4441 aaaaagaaac atgaacacta aaactttctt ttccgttttt cttggttcta tcaaattctt
     4501 tgccaaggac aattagagaa gcttctaatt gataatcagt cataacatca cctcctttct
     4561 agctttatta tagcagaatt gcgaggaaca aatagaaaaa taaggaggta ggaacgtgcc
     4621 gaaaatgaca ttgagagcaa taagaacaaa ttataactta tctgcaaaag aagttgccga
     4681 taaacttaac attcatcaac aaacactgtt gaagtatgag catgatagtt caaaaattcc
     4741 aatggatctt ttagataaac ttgctcgact atacaatgtt gaaaaggatt ttattttttt
     4801 aggcaaaaaa tacgaattaa atcataatct aggagaggtg tgaatgaacg agcgagagtt
     4861 atagaaaggg gattaaatat gaggtatgca gtatataatc aggaatactc atgggaatta
     4921 cacatctttg aataatgctt atgctcaaga caaacgttta aaggcaacaa cgataggtat
     4981 ccttacagta atcttgatga ataagtctga ttgggttgtg tatcctgacg agattgcacg
     5041 acgtctagga ataagcaggc gcaccgtaga tgagcacttt aagcttttag agaaagcagg
     5101 ctatctcaga gtatatcgct tagggttagg cagaggtaaa ggtgtaacgg tatatagatt
     5161 tttttcagat atgcctattt cagatgatta ctttgagtat ctaaaaacta atcttgagaa
     5221 agagttatcc acagataacg gagtttaaaa atacagttgg aaaatattgc catgtgtaaa
     5281 attgccatgt gtaaaattgc catgtgtaaa attgccatgt gtaaaattgc cctctaataa
     5341 gtactaacta tacaacaagt actaactata caataatcta agcctaacgg cactaactta
     5401 gtaataacta ctaacttaca acaaactaat acttctctaa aaaataaaag agagaaattt
     5461 caattttagg actttgaaaa ataggaaagg agaaaaaatg agaccaagac gatatccgta
     5521 tagtgggaaa aaagagtcca cctttgtaaa ggccgaccct gagttagttg aaaaactttt
     5581 aagaaacact agttatcttg agtgtttaca aaaaaagcct atcaattttc agatagactc
     5641 agaagaattt aagcgtctta gctatgaagc cattcatgat acttctcaag taactcaata
     5701 gtagttatta cagaagtcaa accactgacc ttccccagtt gcaatccgtc tgtatggtca
     5761 atctgtttag tagcttcatt agctttagca gagatagctt gcatatcttc agctgttaaa
     5821 gattctcgaa aatctttaaa ggatttcata aaaactcctc ctttctattg gaattttgac
     5881 taaaacggtg agaggtccta gtcgagatta ttatagcaat ttaggaggat attacatcgg
     5941 tcttgaggct gatttttgga ggcaatattg gaagataaaa tcatagaact tgctgactac
     6001 ttcatcagcg aatctacaac gtacagagaa gctaaaatag cgtgtgagaa gctattgaaa
     6061 caagtcagcc atgagataga actcagggca atggaaagta agacagtcta gaagacaaca
     6121 aaaagcacct gacggcaatc aggcgcatac taaaaaactt tacaagagga ttataacatg
     6181 aatatgaact taaatacaaa tgaaatttta acaactactg aatatgatat gtttcgcaaa
     6241 attagtaata gaaaaataac tgaaaatcct aaattggaag aggagctact ttctgaggga
     6301 caacgtcagc cgattttggt aaatgaaaaa atggaagtta tcgacgggca acatcgtctt
     6361 tattacttga gaaaacatag aaaaccagtg cgctacataa ttgatccgac cgctaatttc
     6421 aagacagtaa tttcgatgaa tacatcagct gtcaactggg cattacaaga ttatgtgtat
     6481 tcgttcgctt tagagggaga tcctgaattt gttaaattag ctaaattttt agacgagaac
     6541 gaattgctta gtgacaagat ggtaatcgta gctggttcag gaagacgtga tggtacggca
     6601 gcacacgtag tcaaaaaatt aaaaaaaggc gattatgtat tttcaaacga aaaacagtta
     6661 agagaatttt gtaagttcta cgaacgcgtt ttaaacgaaa caaaactgcc taacaaacca
     6721 tttttacaat ctgttttatg gactttgtat acaacatcag tttttgatga aaacagaatg
     6781 ttgacacaat tgaagaaatc agatttgaca tcagaagata tcgaaggatt tgcaaagaaa
     6841 aaattgctat taactttttt agagctatac aacggaagat ggagtgacga tcatccttct
     6901 ttaattcaat actttatcaa cagaaaaggg tcgttaacaa ttcctagttt gcctaaacaa
     6961 gatgaagata attaaaaaag taggaagata aaatgaaagt cacagtatat gtttacggcc
     7021 gaaaattaga accagatgaa ccaattatca tcccagaaaa tcatcgtttt tatgacattt
     7081 ggaacggaat tgtaaatgaa atgctcgaca acgaggagga tgtagcttaa tgaaactact
     7141 tactaaatta aaactcagac tcgaaggagt tcttaaatca gtcaaccttg actggagaga
     7201 ggtagcagtc gaacttatga acgacctatt tgaggagcgc aagcgtcgct ttgctttcga
     7261 gcaagaaaac tatgacttga agcaggagct tgctgcctac aagtacaaag aaaactttga
     7321 tatcaaggct agactgcaag gagaaatgta gatgtacatt atatcgattt atgtcaagaa
     7381 tactgaaact ggaaacgagg atttcagttt gattggacgt gatttcttac cgacggggca
     7441 ccaagactat attgcaagag tttttggaac aaaagaagaa gcgattgatt acttaaaatc
     7501 tatatcttac atcgcatcag gtgttcatgg taacgattgg gtttatcaaa atgaaaaact
     7561 accagaaatt gagtcacgtt gccgaatttg gaaagtagga gaataaaagg agaacaatat
     7621 gtttaaagca ctaaaaacaa tcaaaaaaat caaacaactt cagaaagaaa tgcacgcttt
     7681 cagccttgcg tttctagctc tacaagatat gggcttgatg ccagaaactg aaagaagtaa
     7741 ggcaaaggct caaacaatgc acgatgtaag ccgcgtactc aaggacgtct tggacggcaa
     7801 gtcggtagat gaagcgataa agcgtctaaa tagcgaagtg aaagctgaag aggtggggca
     7861 gaaagatgac cagaattgaa cttgaaaacc gtgtatggct tttggctaat catgaagaaa
     7921 aaaacgaatt gctggatctt gggctaacgt caaagaccag atatgtgaag cgagttctgg
     7981 aactaggaaa ggtgtatgct catgtttgat tatgacagag atataatgca accgcctgaa
     8041 gaacgagaag aacgtgaccc agctgattgg attttcagcg ctggtcaatg gatctatgta
     8101 ggagattgtt agcctatgaa tagagaacac aacgaaaggt agaaggaaat gacgaataat
     8161 caaattgtag aagcaaaagg cgacttttta accaacccac agctacttaa tagcggtatt
     8221 atcagaaagt atcttgaccc acaaggaaaa gctagtgatg aggagcttgc ctattttata
     8281 gctcaagcca aagcccaaaa cctcaatcca tttacaaaag aaatttattt tatcaagtat
     8341 ggaactcagc cagcccagat agtcactgcc aaatcagctt ttgaaaagaa agcagatagt
     8401 cacccgcaat ttgatggcaa agaggcaggc gtaatctatc tgatggatgg tgaaattaaa
     8461 tactcaaaag gagcatttat tcctaaaggt gctgaaattc ttggcggttg ggctaaggtg
     8521 taccgcaaag accgtactta cccaacggaa acagaagtat cttttgagga gtacgacaat
     8581 tctaaaatac gtgcaagagt taaggaactg acacaacaag gtaaagatgt tacttatcca
     8641 gtgatgaact catacggtaa gccaataggt gagaataatt gggatactat gccttgtgtc
     8701 atgatacgaa aagtagctct agtgtcagct taccgtgagg cgtttcctgc cgagcttgga
     8761 gcaagctatg aggctgacga aattcagctg gataacacac ctaaagacgt cactcctcaa
     8821 gaaagccgtg aggatgtcgt agcacgcaag atggctcaga ttgatcaatt caacaaagag
     8881 caagaggcaa atcatgcaga tcctgaacct gctaaaactg aggagccaat ccagggcgag
     8941 ttgctagacg gtgaacttga atattaggag gacaacatgc aagaattaca ggttattgat
     9001 gataagaaaa tcaataaaat ctatgagatg atcacaacgg atgaacttac tagagagtct
     9061 tttgaaaaag acctcataga ggctactgag aagtacaagg actatattcc tacagctgga
     9121 actctcaaag acgacaaggc aaagcgggct gaatttaaca agttaattga gtctaaaaat
     9181 cgtatccgta ttgacactaa aaacttacta tcagagacag ctaacacatg ggatagttat
     9241 gctaagtcaa ttattgaccc atttgcaacc gtagttagtg aatttgacaa aggtatcaag
     9301 gaaatcgaag aacatcaaag acaactaaaa atagatacgg ttaagagtta cctagccaac
     9361 aaatcagctg agtacatgct ggatcctcgt ctctttgatg aaaaggccct tgagtatgtc
     9421 aaagctagcg attttatggc agatggcgtg acgcttaaaa aagccactat gaagtcactt
     9481 gatgacatgg tcacatttga atttcagaaa caacaagaat ttgaaaaagc caagtcagct
     9541 atttcagggt tatgtgctga gtacggcatg actgactcac cttacattag acagctgaaa
     9601 gacttgactc ttgctgaagt ctttggacaa atcaaagctg attatgagtt tgaaaagcaa
     9661 aaggaagaac tcagacagga tctagaacga gcagagcgat ctaatcagga gcttttagca
     9721 gcccaacaaa ccaaacagca agaacaggct ccaaaatcaa cggaaacccc aaattttgac
     9781 ccagaaacgg gcaaaatctt ggacggtgga caaatcctcc aaaatgagcc taacgctctt
     9841 agaggggctg aaaatgacct aaaacgatat gcccaaaaaa tgactttaga ggtgtatttt
     9901 gtagacacag ccgaaaaaga ccgtttcaag gctggtctaa gtcaactcgg atttgatttt
     9961 aaaaagaact atcaagtcag gggttatcaa cgtatcgatc cattaactca ggctgagcta
    10021 aatgaacaat gtgggtggta agtatgacag aaattgaaaa aatttcagaa gaattggctg
    10081 aatatggggt gcctgatgag ttaataggaa aaatagagga cctattagcg actctgtatg
    10141 gcgaaaaaag gaaattggag atagaaaaat cttgggatat ttctccagag tcaatgggga
    10201 gggtaaccat ggacatcaga aaaatatctg acagcgtagc catctactcg gacggcaaga
    10261 aattgcaggt tatccacaac ctaggggatg agtttatcct agattttaag gtgggagagg
    10321 atagcgtctg gaacctcaat ggccaagtcg tagaaattat tgacatgatt gagcctgtct
    10381 ttaaagtttt cagcttttgc tcaaaatctg gagagggtat gcaacgctta aaacatgcta
    10441 tcgttcactt tgaaaaattt gagcagtaca tcagagataa tcaggaagac ctgatgatct
    10501 ggtggcacaa tccaggaggg gaatatgatt aaaaccgtat ttttttcatg tgattatcca
    10561 catcatgagg tgattgacga ccaaataaat agttggcttg ccgaaaatcc aggcattaag
    10621 ttgattgaca tcaaatttca atcaaatgtg tctgctgtcg ctgacagtgg agtcagtgct
    10681 gaatattggc atacatccgc attgattatt tacaaagttc cctcagagaa caatataagc
    10741 agtattaatt caaatggttt aggtttcata atcagctgtg agaaatgtgg tagcttatca
    10801 ataatcaagg gaaaagatgt aggtcaaaat gtatgttatg aatgcaaagg agagaaataa
    10861 tgaatgattt tatcaaagag attgggatgg ctatcctatg gatgttttta gggtatctct
    10921 tgggagagcg tagcactaga gggggacaaa tcagatgatc aataacgtca cactggttgg
    10981 gaggcttgta gcgcctcctg atctacgaaa aacgcctaat aatgtatcta gtttacaggg
    11041 cacgcttgca gtcaatcgca atttcaaaaa cgaaaatgga gagcgtgagg ctgattttat
    11101 caatttccaa gcgtggagag gtacagctga catcattgct cagtattgca gcaagggctc
    11161 acttattggg atcattgggc gcttacaagt taggtcttac gagaaagacg gtcagcgtcg
    11221 atatgtgact gaagtaatcg ctgagagtgt agctctgcta gagagtcgca acagtcagca
    11281 cggacaaggc aacagtttcc aaaatgggaa tagctcacct tttaccgatc ctaacccctt
    11341 tgacctccca aatgacggtt tgccgtttta ggagggacag ttagtggaaa tagataagat
    11401 tataaaaaaa gatgtcttgg aatttatgga aacaatttct gataataaaa ttgatgcaag
    11461 taaaatcaat gtgacagaac gtattgctat catcattgag aaacaaaaaa tagaggtcgt
    11521 tacgactcta aactatgata tgagcattag ctttgataac aaagacacgg ctcctacact
    11581 agatgacaat ggtgaccttt ttgaaccggt ctacaagtgc aaagttaagg caattcccaa
    11641 aaatgatgta tttttcacct cattaacacg ggtcaagagc aataccaaga cgttacaaga
    11701 ggttaaaaaa ttctttgaat tcgtaaacga aaacagagaa aatctctttg agatggcagg
    11761 atttaagggg gttcttgaat gaaattgacc ctgaacattg agcctaaacc tcaatcacgg
    11821 ccaaggtttg caagacgtgg gagttttacc acaacttacg aagacaagga tatgaaaaca
    11881 tggcgtaatc attgccagct gctcattgct aatcagtaca tgggtcagcc tatccttgag
    11941 ggagctttga ggacacggct tagattttat atcaaacctc ctcagtacat ttctaaagtc
    12001 aagaagaacc aacaggccct cctggatgaa attataccag taggcaaaaa gcctgacata
    12061 gataactacg aaaaagcgct atatgacagc atgtcaggga tcgtcttcca ggacgacggt
    12121 cagatagcgc tacatgatgt aggcaagttc tacagtctaa atccacggat agaggttgag
    12181 attgaggtca tgaaatccct gagtatttga agaaatgagg agcagatggc tgactacgca
    12241 ttatatcaag gtgatgtgtt tgttacgctt ggaacattag cgcagatcag tagcgagaca
    12301 ggaattactg aaaggatgtt aaagtattac acttacacat cacaccaaag acgacaccca
    12361 aacggtaggg ccgttattaa aattgaggag gaagataatg agaattaaga cggaaagcgg
    12421 aggagttgga agatgatgga agagttaaag caaaaagtta atgaagtata caactggacg
    12481 gtagaagacg ggaagccgca acctcccaag caagatttac cacaagcggt gaaagaccgg
    12541 gcggactatt tttgggaaat ggcagaagat ggtatgacgt ttatgggagc gatggaatgc
    12601 atcttcgctg atgaaaagcc tatagactat gatttgggag ctactaagga ttggttgcca
    12661 aaatctaagg agtttgatga ttgggttggt tattcgccaa gcatggctca ggtagttatt
    12721 gcagtttatt tgatttatag aggaaactaa gatgaataag caggaattga ttaaaaaatt
    12781 agaggaacga agaacaataa ctgggaattt tcaaggttat gtagtttggt ggaaggatgt
    12841 aaaagaaatc tttgaacaac tagacgaatc cgaaataggt cacgcagatg aagctccacg
    12901 ctacgtaaag aacatactag cacgattgcg agaattgcca ttgcatgata gagaggtttg
    12961 gttaaaggct atcatgagcg aatttgaaca ggattttagc cgtgcaaaat ggcgagaggg
    13021 ctacgagcaa ggtaaaattg agggtatggt tgaacgtgaa aaagtcatag ttccgcagtg
    13081 tgtggcggaa tatatagaat ttaaaaagaa aaacaatttt catgtttacg gtgcaatgag
    13141 agtaattgaa gatcattatg ataagaaagt tcctgattgg ttttacgaaa ataacatcga
    13201 aaaattctgt cttgcttggc ttgacggcta cgaggttgaa aaagagaagc ggtattttgt
    13261 taagattaaa gggaatatta aagaaaatat gttggtttat ggagaacttt tgaaaaggta
    13321 tttctttaca aaaagcttta gtttagacga tgttatatat tcccacaccc gtaaagaact
    13381 agaagacgca aagttcggct gggtgtttga ttgtccaggg attgagattg aggaggtgga
    13441 gtgatgagcc ttacgctaaa tagcacaatt ggagacttag ttttggcaat cggagaaatt
    13501 atcgttggtt ctgatggtaa aaccactaca gcgatactgg agatacctga tcaaagcttt
    13561 tacttagaga ttgagcttaa attgaaggag gaggtcataa attgaaacga ttcatagcta
    13621 tctggattct gctatctgct ggattgaata tctggcagat ggacaggatt cgagatttgg
    13681 aagagaagaa gccgatggtt atctacaagg ctgataacgc aggcgttgag atattcggta
    13741 aagtcgtcga gaaaggacgg catggcaagc tatatacgct aacgatacgt gactatggtg
    13801 tgttcgtggt tacgaaggac gtgtacgata aagtgaaagt tggggatgag gtgttactat
    13861 gacagaaact attaaactac cagactatta tgagcctgat tggaaaaatg caaggtacgg
    13921 gtcgttggaa gagcttaaag aattgttgct ctttaagcgt attgtgaaat gggataagga
    13981 ctttttgctg cttgaagacg gcacaaaggt cactattgaa atgtctgaaa gtgattgctg
    14041 tgcctcagca ggtggggagt tccaagatgt atcacttgac gctgtgatta ctaatattga
    14101 aattggagaa ccggaagaaa tccccgacca ttggggaact ggttataaaa acaaagtaac
    14161 tatcttccat aatcagaacc ctgtagctat tgccaattgt gaagcagagc ataacggcta
    14221 ttattacagc gtatgctctt tagtgattgg tgatattcat tttccagttg ttaatgctta
    14281 ggaggattta acatgacacc aagatataga gcgtggataa aaacagaaaa acgtatgttt
    14341 ttttcagatg acattcttgc tattgactac gaaaacaaag aaatagtgac acaacaagtt
    14401 tattttgaga atggtttacc agacgataga gatatctatt gttatgattt tgacgaaatc
    14461 gaactcatgc aatcaacagg actcaaagac aagaacggca aggaaatctt tgaaggcgat
    14521 attgtacgaa ctactagatt tttgggtaga gctgacgaaa ttggcggttt ctatgagtat
    14581 gacaaggaat ttatagggat tgttaagcag cttgagggtt cttgggtaat tgatacgggc
    14641 agtgacgcag tatgtttatg gactgaaatt gaagaaaatg aaatcatcgg caacatctat
    14701 gaaaataagg agtttggagg acgcaaatga gaccttgtaa atatccatat tcaggaagaa
    14761 gaaaaaaaca agaaacgccg tcgccaatat tttctgcacg accaattttt gacgaagttc
    14821 caattgtaga agaagttaag gttgagttcg gagttgaagc tagtatgggg cgcatatatc
    14881 cagaaacgtt aatacattta gatatttctg gatacggaaa tagagtgcat tcagtacatc
    14941 gcttccccgg tattttactg agtgttggtg agtcaatcca actaaagatg cttttctata
    15001 aaagacttag aaattttact acagatcgtt tcttgacgtt tagagaatct gattggaagt
    15061 tctttatccg ggacctggtc aacgaattta agcattaaaa aaagccaaga cactctctgc
    15121 ctcagctaat agttctcgca aagactatta tatcacaaag gagacagaga gtgaacaagg
    15181 ctaaagagct cttgaaagag ttgcaggatc tggacatgga catccaaagc cgtatagacg
    15241 aaattaacga gcttgaggca ggtttgctct caagccctaa atggtccgag gttaaagtcc
    15301 aaggtggaca gactagaaaa gttgatgatg tctatactca gttggtagtg atgaaagagg
    15361 ctatagagca ggatactaaa gaggtcatta acagaaaact tgaattaggt agaatgatca
    15421 ataggcttaa aaatccaaag tacagggcag tattaagaat gacttacatc aacaaaggca
    15481 ccgctgatag cgtttgttat gatttgaata tgagtcgtac aacctactac aggttaaaaa
    15541 atgaggcggt cttagctttg gaagaagtca tctaacctca tagtgagctt atgggacttt
    15601 ttggaacagc acggttctaa aaatctgtta gaatggtagt atcaagaatt gaaaagagag
    15661 gtctcagaat tggtagatgg ttacctgtaa tgtaaggggg ctgtcatggc cttggaggtt
    15721 caagtcctcc cctctccttt gagtgtttgt gtcccagaat gagttaaatc ttctgggtgg
    15781 ggattcacat atcactcatt aactcctatc actcattaac ttaaaaatgg ttgcggaagc
    15841 gactggacct cgcatgattg cgtagctaat tatattccgg ataagttata atctagaggg
    15901 tttgattccc tcagaggttt taaagactac aaaaaataaa aaagaagtca aaatttaata
    15961 cgcacgcaag gttgtagtcg ccttgcaaga aggtcgcaca tcgtgtggct ttttttgatt
    16021 attcgaaggg tggtgatgga aaattgagtg gattgagaat aaaacaaaag agatttgcag
    16081 atgagtacat catctcaggt aatgcgacgg aagcctataa gaaagcaggt tatcgtgttt
    16141 ctagtgatag agtggcaggc gttgaaggac ataagttact aaagaatcct aagattaaaa
    16201 gttatataga tgaacggttg aaacagcttg attctgaaaa aatcgcagac cagcaagaag
    16261 tccttagtta tctaacctcg gtaatgcgag gagagacgca agaacagact ttgataagca
    16321 tcggagaatt gggtcaaacg attacggata ttgatgttgg agcaaaagac agaatcaagg
    16381 cagccgaact attaggaaaa cgtcataggc tttggacaga caaagtagag gcagacgttt
    16441 ctgggacggt ggtgtttgca aatgagtcag acataccaga ttaaacagaa cgatattgtt
    16501 gttgacttac ctaagacagt aggagctgga tacggacagt tctggcgctc aagaaatctt
    16561 tatcgtgttg taaaaggttc ccgtggttcg aagaagtcca agacaaccgc tttgaattat
    16621 gttatccgtc ttttgaagta tccctgggcc aacttgcttg ttattcgtag atactcgaat
    16681 accaacaagc aatcaactta tacggatttt aaatgggcgt gtaatgtgtt gggtgtgact
    16741 catttgttta aattcaatga atctttgcct gaaataacca taaaagcgac tggtcaaaaa
    16801 atcctattcc gtggtttgga tgatgaactc aaaatcacat ctatcacggt cgatgtcggc
    16861 agtctttgtt gggcatggtt tgaggaagca tatcaaattg agactgaaga caagttcagt
    16921 acagtagttg agtcaatccg tggtagctta gatgtacctg atttctttaa acaaatcaca
    16981 gtcacattta acccgtggaa tgagaggcac tggctcaaac gtgtgttctt tgatgaagag
    17041 actagccgag ctgatacatt cgctactaca accacttaca aatgcaatga gtggcttgat
    17101 gaagtcgata ttaagcgcta tgaggacttg tatcacacaa atccaaggcg tgcgagaatc
    17161 gtttgtgatg gtgaatgggg agttgctgaa ggtttaatct atgagaacgt gaccgtcaag
    17221 gatttcgata aggatgaatt gctacgagat tcagctaata agttatgtat cggtcttgac
    17281 tttggtttta ctcacgatcc aaccgctttg tgttgttcgt tgataaatga cacgacgaaa
    17341 gagatttatg tctttgatga ggcgtataaa gtcggattga taaccaaaga agttgcgaag
    17401 atgataaaag acaaaggtta tcatcgctca caaatcattg ctgatagcgc agagtcacgg
    17461 ctgattgaag agctcaggtc agaacatggc atatctagaa taaaagagag tcggaaaggt
    17521 aaggatagta ttatggcagg cgtatcaaaa ttgcaaggat acactattta tgtgcatcca
    17581 gattgtaaaa acatcatgga tgaattttat agttactgct accagcgaga taaagaaggc
    17641 aactggttga ataaaccaga ggataaaaac aaccacttga tggacgcttt gcgttacagc
    17701 cttcaatgta tcgaaggtgg gaaagcaacc gtccgcagac gttctgatta tggtctatag
    17761 agaggaaaga catgtaccaa tatttaacct atccacggga tggatatgat gagggttctt
    17821 tgaagaaaga cctgatttac aaattgataa cgatacatag cactgaaggc tcacatttga
    17881 agaagcttaa aagctactat ttgggtgagc atgctatctt agaacacacg agacgcaacg
    17941 tgaacgcacc taattacaag acggtagcca atcatgccaa ggatatcgca gacacggcta
    18001 cgggctattt tatgggcaat cctatcaagt ataacaatac tgctgacggt gatatcgatg
    18061 aactacttac agcctttgat ggtgctgaga ttgaccaagt agatgctcag aatgctttga
    18121 acatggctat ctatggtcgt gcttacgagt acatctatgc taaagagggt atggctgagt
    18181 tggattcaac tagtattgat ccggagaata ctttcatggt ctacgatgat agtattgagc
    18241 ggaagccttt gtttgcggtc tattactatg aagtaaaaga cgatacgaaa gacactacca
    18301 agcaccaggc tgaggtcttt accgaaaatc tgcactatca catggtgctg agaagtacag
    18361 attcaggaac aattcagagc gaggaggcaa cacctcacaa ccttggtcaa atcccaatta
    18421 tcgaatatcg caacaatcac tttgcaattg gtgactatga gcaacaaatt agcttgatag
    18481 acgcttataa ttccttgatg gggaatcgtg tcaatgataa ggaacaggct gtagagtcta
    18541 tacttgtctt gtatggcacg cagttagcag acactccaga agacgctaag gtagcaatga
    18601 agattctttc tgaagaaggt cttttggaat tgccgggcga tagtgcaagg gctgagttct
    18661 tgaagaatac gctggacgaa agtgctactg aaatcttgcg tacagctctt aaagaggaca
    18721 tctacacatt tagccatgtg cctaatttga ctgatgagaa tttcgcaggg aatacatcag
    18781 gcgtagccat ggaatttaag ctgatgggcc ttgagatgat tactaagacc aaggaagcga
    18841 actataagcg aggattgcgt cagcgtattg cgatttttgc tcattactta ggcatgaagc
    18901 agattgcttt agagtctcat tcaatcgttc cacaattcag tcgtggtttg cctaagaact
    18961 tgttagaaat ctctcagatt gtgaacaatt tggaaggcaa agtgaccaat agacagctta
    19021 tttctctctt gccgtttgtg gaagaccctg acgctgagct ggaagccttg gaagaagaga
    19081 aaaagaagaa catggaagac atgccgatgt tcaacaaaga caacacgaaa cccgaagacg
    19141 aggtagagga tgaagaatca ggagtattgg gcgaagagga aagccaatct gatttaccag
    19201 cagatggaca aggccgaaaa gcaggcagat cagttcgata aggtctatca ggaagccaag
    19261 acttacttgg ataaggaagt caataagatt tttgataagt tccaacgtga ttatggtcta
    19321 agtcaggtag aagctagaca agtcttgaag aacatgaaag acaagaaaaa tctgaatgaa
    19381 cttcgtaaag tacttgaagc gagaccgaat gacccgaaca tccaaagatt actagctgac
    19441 ttagacagcc cagcttattc tttccgtatg aagcgcctag agcgtttgag cgacgattta
    19501 gaccgtatgc gtgaatctat ctatcattca gagaagacag gctcagacgc cttttatagc
    19561 gacctgatga aggatagtta ctacaaggct acctttgacc tgcagcagca gacaggacta
    19621 gcatacggct tttctgggct tcctgagagc gagattaaac atctacagtc ttttagttgg
    19681 gtaggagatg gaagtacgta ctcaacaaac atctggaaga atacagggaa gcttacatca
    19741 agcataaaag atgaattact cataagcctt atgacaggcc gagatacacg agaaactgca
    19801 caagcaattg ctgagaggtt caatgtaggt cagaacgatg caagacgttt ggttcggaca
    19861 gaatcagcct tttttcataa ccaaatggaa ctactcagct atgaagaagc agacatagaa
    19921 aagtatatct ttgcggccgt cttagacaag cgtacatcac ggatttgtca ggagcatgac
    19981 aatcaggtct atgataggga caaggctgtc cctggcgtca attgtccgcc tatgcaccct
    20041 tggtgtaggt ctactactgt cggatacgat gaggacgcag attacagcaa gttgaagcgc
    20101 agagcaagga atccagagac agggaagacc gagctagtac ctgctgatat gacttataaa
    20161 gagtggtata gcaagtatgt tgcgaaagac ggggaaaagg tgtataatca agatacaaga
    20221 gaagccaagg cgaaatttta tagcgaacaa ctattgtcca aaatttcagg agttgagcca
    20281 aaaattacaa gtgatatgca acgtatcgca ggagaaaaca aattggcagg tcttgaattt
    20341 aggaagaaaa cagttgagtc attatcacgt aaaattattg cagatagcct agttgaaaat
    20401 ataagtttgt caaaagccgt gagtaagatt aatgacgcct taaggtacac aactattttc
    20461 gattccgata cttttacaga agagtatttg aagatgaaac agaagcttat cgcagaaggt
    20521 tataaaattg taaaagtaaa aaacacttgg ccagtagatg gaccatacaa aggtgtgaat
    20581 acagtcgttg aaaaagatgg tatcaacttt gaaatgcagt atcatactca ggaaagtttc
    20641 gacttaaaaa atggttcatt acatgaactc tatgagaagt atcgtgatac gaatacatct
    20701 gatctagaac gcatgaaatt atttaaggaa atgcttgatt taagcaatgg gcttgagatt
    20761 cctaaaaata tagagagggt gaagtgatat gaaagatatt aaatactacc gcacaacgac
    20821 gaacaatgct caagtacttc gtttgattga tggtgtcatg caagtttttg acattgaaaa
    20881 aaagtgggtt aatagcatgg attggtttaa taaaatcttt tttaatgact ttacggattt
    20941 tgaagaaatt tcagaaaatg atgcatttac ttatattgac aggatggtag cggcatgatt
    21001 gatattgcct tggctatcgc taaaaaagca catgcagggc aggtagataa agcgggtgtt
    21061 gattacatac agcatcctct ctatgtggcc agtcaagtca acactgaaca agaaaaagct
    21121 gtcgctcttt tacatgatgt gattgaggat agcgatataa ctgctgccga tttattcgcg
    21181 tctggcttgt caaatgaagt tgttacagcg gtacaaattt tgacaaagaa aaaaggtcaa
    21241 agttatcaag aatatcttgg gaaagtaaaa tcaaataatt tagcaagagt tgtaaaactt
    21301 gcagatttga aacataactc agatttatca cgtttgaaat ctgttaccaa tacagactac
    21361 gagcgtgtta aaaaatataa aaatgcaatt tattacttaa gcacctagag aaatctaagt
    21421 gcttttttcg tgctcagaaa ggagaatctg atgaacaagt acaaaaagtt gatagaattg
    21481 attgaaaata acggtcttga gatacaatct aagaaatgtt atgatccaca gagtgcttgg
    21541 catggtgagg agttatggat tgttgataag aaaaaacaaa ataaaatttt tgatttatca
    21601 ggtaacggtt actgttttca tgacgctaaa gttgaggaag ccattgaaga agttgagaag
    21661 tatctattat tgaaaaagat ggatacgttt gatgatttca aaaaatgggt ggaaaagaat
    21721 gctaagccta aaaaatgatg cttagaaagg agtgaagata tgtttatttg ggattgggta
    21781 tcaatcgctt tcgggtggtt ggtatttttg tttttaatgc tatttatcat agcgtttgtg
    21841 aaaaaagtaa ttgaagaaat caaaaaataa tctaaccgta tggaattccg tacggttttt
    21901 atattgtcca aactgtaccg atgacattaa aagctgtacc gttccgtcgc cggacgtaaa
    21961 acgagattat cgagtggcga cgtaatcgct ggaggacaat tatgtcagaa gaaatcaatg
    22021 caactgtatc tactgaatca actgagactg tcgacactca agaaaatgtt gatacggtgc
    22081 aggaagaaaa gcacgaacga actttcactc gtgctgaaat cggtaagatg ctatctgccg
    22141 aacgctctaa atgggaagct gagcaagaag ccaaggaaaa cgaagctaag aaacttgcca
    22201 agatgaacgc tgacgagaaa cagaaatatc agttggatca gcgtgagcaa gaactagctg
    22261 accgtgaaaa agctattgct cgcaaggaat tgaccgcaga agctaaagca atgttaagtg
    22321 aacgtgactt acctgttgag ttagtaaatg tagttgattt gacaagcgca gagacggtat
    22381 ctgaatctat tacctctatc caaaaagcat gggaagagtc agttcagaag ggagtttctg
    22441 aacgtatgaa aggtagtgca cctatcaaaa atgcacaaac agtccagcaa gaagtcacgg
    22501 aaaaatggcg taaagacttc ttgtaataaa agaaaagagg aaaaataaat ggcatttgaa
    22561 gaattaaaca cagcagaatc acgcaagaaa catcttggga ttattgagga tgtgcttgcg
    22621 gtaaattcat attcaacacc acttgtaaca tcaagcgatg cagtaacctt gcaaggtcgc
    22681 tcttttacag tagcaactgg taacacaaca gagttgaaag actacaaacg taacaaagac
    22741 aacgaatttg atcacgttga agttgaagaa aaggtttata cccttgatga agaaaaatac
    22801 tggggtcgtt tcgtagatca attggacgaa cgtgactcta atggtcaagt gaatatcaat
    22861 tatgttattg cccgtcaggc tgcagaagta gtcgctccat atcttgatga actacgtttt
    22921 ggtgcagcac ttggaaatgt aagtgacaat gttgccatgg gtaaaacagc aggagcgaac
    22981 aacgcttata atgcggttct tgatgtgtct gagaaacttg atgagcttgg aattacaaaa
    23041 gaacgcttgc tcttcgtcac tccaagtttc tacaaagcga tcaagtctga aatcgttcgt
    23101 ctaccacatg gtgacgcaga taagaaagtc cttggaaaag gatatgttgg tgaattggat
    23161 gattacacag tctataaggt tccttctaaa ttcctgaaag gtgttaatgc ccttgctact
    23221 gctccaggtg ttgttacatc tccagtacaa gtagataata ctaagtacaa cgataacatt
    23281 ccagggcgat ttggcgaatt ggtagagcaa ttgctttaca ctggtgcatt tgttcttgaa
    23341 cacttcaaga aatacatcat cacaattgca gattctaagc ctgctgctaa accatctact
    23401 caaggtaaag ttgtaaaccg tgctaaagcg tggaaaactg gaacaaccta caaagaaggt
    23461 gacacagtta ctcatgccga taaagtctat gtagcggtta aggatatttc taattcatca
    23521 accgcaccag acacagatac aactaactgg aaagaaaaaa ctggtaagaa ataggtccga
    23581 gttatgaaat ttaaaatcaa acaagatttc tatgattggg aatcaaatgt gaaacgactg
    23641 gcaggagagg aacttgagat tactgaggag cgctatgctg aactggctga caatattgcc
    23701 agcaacggtg tcgctatctc agatgttctt gaggaaatct ttcctaaacc tgagttctta
    23761 gaagaggatt gatatgtcta tagagttgct gaagaaatta acaggcgaag aagatactca
    23821 gcttctcatg ttgctccaaa caagggctac aaatcttatc ttgtcagaga ctaatcgcac
    23881 atctttgaca cctgctttaa gtcttttaat acctgaggtt gctatcgaac tccacaaccg
    23941 ctcaggagcg gaaggagagc attctagaac cgagggtggt atagcagtag tctacggaga
    24001 aaacggcctg tctacggatc ttctacagcg aatacgcatg cacaggctag caagggtggc
    24061 aggtcatgtt tttgaagcag agtagactga aaccttatcc aatgcgacgg tttgaaaaga
    24121 ctgtcactga ggaaggtgtc gcgaaagaag ggtatgccaa ggaagctgag acagtccgcc
    24181 ttgaattgtg gccagctagt agcaagctac aatctgaatt gtatggcgag cgtgtcaatg
    24241 atattttgaa cgcaaatgcc aacaagtcag ctactatcaa agtaaaagat ggtgtgtgta
    24301 tcgatagtca gacggaagtg actcataggg ttatttctaa aaaggtctac acacatcatc
    24361 aagttttgga gttagagcgt gtcagggcta ctaggggcag ataggcttat agctaaatgt
    24421 agacgattgg ctagtaaaaa aactggcgag gatatcgtct tacgtgcggt gcacaatgct
    24481 actataaagg ttgtccaagc agatgcaaga agactcgcac cagcgagaga tggagagctt
    24541 ataactagta tcaaaactag ggcaaaaatg gacggagata gggctatagg cgaagtttac
    24601 accaacctta aatacgctcc ttatgttgag tttggaacgg gaccaatagg acaagctaac
    24661 cattcgggta tctctccaga ggtcagcgta acttacaagt ctaatccttg gtatgtgcat
    24721 gaagaccaaa tcaatgtagg accgtaccac tttcaaaaga ttggggagtt ctacaagatg
    24781 tatggtcaac ctgctcagcc ttatctttat ccagctttga gagacaatca agagcgtgtg
    24841 tctaagaata tttcgaatta tgtccgtaga aagataagag aacaaataaa atgattaata
    24901 tcaagcctgt tatttataaa gaattgcaaa aggttgcaga taatgtgacc gatacttatc
    24961 ctagcgattg ggagactttc ccagtcgtta tttttttgga agaacaaaac aagccgggtg
    25021 attggtttga tgaccaggaa caaaaatcct ctatccgcta caaggtggat atctttgatg
    25081 ataccagcac tagtgagtta gctgttaaaa tcaatcagat ttttgagtct ttaggtttgc
    25141 gaagaactga ctgccaagac gtgccagacc cgtctcattt gagacataag gtcatgcgtt
    25201 ttgaaggtat cgtcgactta cactcagagc ttgtttttca atttagaatg gagaattaaa
    25261 catgttagca aatggaatta cgctttctta tggcgaaaca aaagatagct atactaaact
    25321 tgttggattg aaagaagtac cagagtttgg tattgaactc gaaaaagtag aaaatactac
    25381 tcttgaagat acggtgaaga agtacgagtt tggtattggg gacataggag aacttgagta
    25441 caagttctct tataataatt caagcgcaac tgctccttat cgtgtattgc gtaaggcagc
    25501 agacgacaag aagaaactct actttgaaca agcttatcca gacggtacta aggtcatttt
    25561 tgaaggccaa gtatctgtta agcttggcgg tggcggtgtc aatgccgtta tcgatttcac
    25621 acttaagatt gccttgcagt ctaatcttac atttactgat ggtattggag gttaattaaa
    25681 tggcgttaaa atacacaact tggaaagtta ctgacgaaaa agagttgaag ctacgtttga
    25741 catctcatca agctgcaact gtggaagaaa aaatcggcat gaacttgctg aagattttca
    25801 tgcctgaagc tggcgaagag ttcactttac cgcctttgaa agttatgttg ttgttagttc
    25861 acggagcctt gcagcagtat gaacatgggt attctcttga ggatgtctat gatttatacg
    25921 atgaatacgt ggacaatggc ggagaccaaa caaccttcat gacagaggtg ttgatgccac
    25981 tctttgaagt atcgggtttt actccacgag gaagcaagga caagaaaact tccaagaaga
    26041 aaatgacagt agacaagtaa tcttaacggt aactcagatt attgagaggc tttatcctat
    26101 gtttttggac atcgggggca agcctcttga tttttgggat ttgacggtac ttgaaatcag
    26161 agaaatgatt gaaagctata accgtgtcaa aatccaagag cgtaaagaaa agattattga
    26221 ctcatacaga ctttcgcaga tgatatccaa ccacgtttct ttattgttat ccaaagatgc
    26281 caaggccttt gagttctggg aatatgcgcc tgagttgttt gtagaagaac aacaagcagt
    26341 agaacaggaa cgacagaaac aagcactttt gttgcataag gaacggatgc gtgaatttgc
    26401 agagagacat aatcgaaaaa ggaaggagga agtaaatggc aactcttgat gaattgaaag
    26461 tcatgattga cgctgagata gcgcctttca ggaagaagat gaaagaagtc gagaatcagg
    26521 tcaaaggaac atctgaccaa gtgaaaaatg ctactgccaa agttcgtgaa cagtcgagct
    26581 caatcggtag tgcgtttggc aagctggcta agttcgctgg ttttgcaatc cttggtaaga
    26641 aattacttga tgttgggatg tattcaacgc agacggctct tgaagtatca gcgtctatga
    26701 accaaatcaa gcgacagatg ggcgagagtt cgcaatcttt cttaaaatgg gttaacgata
    26761 atgccaacgc tatgaatatg ggtgtgggtg aggctaccaa ctacggtgca gtctactcaa
    26821 acttattttc tggatttatc aaagatacca acaagctaag cgcctatacc gctaagatgt
    26881 tgcagacatc ggcagttgtt gctgaaggtt cagggcgcac gattacagac gttatggagc
    26941 ggattcgctc aggtttacta gggaacaccg aagcgattga ggacctagga atcaacgtca
    27001 acgtggctat gattgagtcc actgaagcct ttaagaagtt cgcaaacgga cagagctggc
    27061 aacagttgga ttaccaaacc cagcaacaaa tccgccttat ggctattctg gaacaggcta
    27121 cagccaagta tggggatacc ttgtctaatt ctgtaaatgg tcgtatcagc ctatttaagt
    27181 cgctgatgaa ggacgcagca ttgaaccttg gtaactctat gttaccgatt atcaatgcca
    27241 ttatgcctgt cttgaactct tttgctatgg tcttaaagaa cgttactgct aaactcgctg
    27301 agtttatcgc tttgatgttc aacaagaaag caacagtgaa agatggtgtt ggtggagcag
    27361 ttggagacat gggtaacgcc atgaaggatg ctgcaggcgg agcaggagac cttgctgacg
    27421 cagtagacga cgctggagat tcagcaggag gacttgctga caatcttgga gactccgcca
    27481 aaaacgctaa gaaggccgct aaagagttgc taggtctttt gggatttgat gagattaaca
    27541 tcttgcaaaa accaaaagat gacgacgcag gcgggtctgg aggcggtggc aaaggtggta
    27601 aaggaaaggg aggcggtggc ggacctttca aagacatctt gccagaagtc gagttgaccg
    27661 acatggacaa caaattcaag agcatttttg atggtcttgg agataagctc aaagggttgt
    27721 ttgacctctt caagaaaggt tttgatgcag catttagacc agaaggtata gaacgcatta
    27781 agactgcctt agaccaaata gctaagacaa tgggagaaat cgccactgac ccaagggttg
    27841 tgaatgcctt taaccgaatg gctgagaaaa ttgcttatgc tttagggcaa gtgacaggct
    27901 caataacaac tatcgggcta ggtatcggtg ttttccttgc cgaaagtatt gcaaatggcc
    27961 ttggaaggca aaaagaacgc attaccaggg cgctagtcgc tttgtttgat aatattggta
    28021 acatttccga ggcagtagga aacatcgctc aggacttttc tagtactttc tacgacgtca
    28081 ttacctcaac tggtgcggtt cgtatcggta gcgctattgt gtcaactctg ttgagtttga
    28141 catctaccat tgttgaagtt ggtagtaaat tagcaggaag tttgtttaaa ggttttgaaa
    28201 aagtcgttgt gacaagcgct cctaaaattt catcagtctt ccaaagttta ttagatactg
    28261 ttgcgcctgt atttgagagc attgaaaggt ctgttaacaa atttggcgat ggcttaagtc
    28321 gtgtttatga tgaacatgta gcccctgcta ttaactctat tgctaatgct tttaacggac
    28381 tgattgatat catacaaatc ctctgggaga attcttggca accttttgct gagtttttat
    28441 caggagtatt cggtgttagt attgaaggaa tttcagattt attaggaggt ggccttttag
    28501 ccactttggg actattggcg gatgctatta agttagtggc agatggtttc accgtttttt
    28561 ctgactggtg taaagaaaac aaagaaccta tcttggcttt gataacaact tggcaaacga
    28621 ttaatttctt atcatgggct gaacaagccg ggggacttgc aggagcattc agcttgttag
    28681 gtagtaaggt ctctttgatt gttggaggga ttaagaatct aggtcttgct attaaagcat
    28741 tgacatttga taagttggtc agttttgctg aaacaatcta tttgaacacc ttatatgcaa
    28801 aagattttgt ggtcaattca ggtaaaacaa ttgcacagct aggaaaaact gctttagaac
    28861 ttggtaaatc agctctagca tggactgctc atgcagcgaa aatgggatta gcaaccgcgg
    28921 cggaatttgc acattctgtt gcagcaggag tcgctacagc tgcaacatgg gcttttaatg
    28981 cagcgttagc agttttgaca agtccaataa catggattat tgcagcaatc gcagccttaa
    29041 ttgctatcgg tgttttgctc taccaaaatt gggacactgt tgttgagttt gctaaaactg
    29101 catggcaagg actatgtgat tttatcagtg gtatttgtca agcgattggc gaatttttca
    29161 gcggtctatg gacgaaacta caagaaatct ttgagccgat aggtcaatgg tttggcgaga
    29221 aattccagca agcatgggac gctattggaa atatatttgg caacttaggc tcttggtttg
    29281 gtggccgttg gaatgattct aaaaacgcac ttgccgaagc aaatacttgg cttggtgata
    29341 agttcaagtc aggtcgggat aaagtgaact cagcttttga aaaagttggc tcttggttcg
    29401 gtgaccgttg gaatgatatc aaagatggag tgaaagaagc tgatacatgg tttggagaga
    29461 aatttgagag tgcaaaaaag aaaactcaga atcctttcca aaaaatcggt tcttggtttg
    29521 gtgatagatg gaaagatatg caagatgcct tgaaagaaat ccccaactgg ttcaagaatc
    29581 tgtttaatga tgcaatggat aatgctaaaa acatcgttaa aagtggtatc gataaactaa
    29641 aaagcttctt taactttgat tggagcttac caaaaatcaa actccctcac tttaatatat
    29701 ctggtagctt cagcttgatg cctcctagaa ttccatcatt ctctgtagat tggtatgcac
    29761 gaggcggtgt attcaactct cctagcatca ttggggtcgg agaagctggt caagaagcgg
    29821 taatgcctct tgaacggaat acaggatgga tttctatctt ggctcaaaaa ctggctgaaa
    29881 gaatgcctgc taataatgta cctacaggtt attcattacc ggctggcgac atcgttatcc
    29941 aaatcgcagg ccatgagttc ggacgggtag ctatccaaga aatcaacaag gaacatgaac
    30001 gagcaggtca aaccttgctc aagatttagg aggttaaatg gcacaattga caatcaatgg
    30061 ggtggctgtg aagcctccca aatcttttca agtcggtatt caagatatcg atggagagac
    30121 agggcgtaat gccaatggcg acatggtgcg tgaccgtatc acgaccaaac gcaaactaga
    30181 ctgtgaatgg ggtatgatga ctcagggaga aataagtcag cttttacatg ctgtatcatc
    30241 tgaatttttt gaggtatctt atccagaccc catggatggc caagtcacaa agactttcta
    30301 tgtcggtgct aggacagctc ctagctatac ctttactgag aagtttaaac cttggtctgg
    30361 cgctaaattt aatctggtag agaggtaaga aaatggacgc tttaactaga cgacaatttg
    30421 acagatctat gtttgccaag gaaaggacgc tggctattcg tgttggtgaa tatgcttcac
    30481 gggatatcaa agaggctagt tttgagtatg gctacatcaa gggcgatact tataagcctg
    30541 gtggaacctg cgctggtagc ggtaaaatta cctttaccag tatcattacc acgttcaata
    30601 agctggatac cctgcaccct gagattggtc tactggttgg ggatacctac cagtgggtca
    30661 agatggggga atacttcatc aacgatattg agattgaccg aaaccgaaac actaccacgc
    30721 ttgaacttat ggacggtatg tttaagctca atcgtgagta cgtgacggac ttgcatttcc
    30781 cagctgaagt acgagaggtt attcaggaaa tctgcctgaa aacaggcatt gagttagcga
    30841 atgactattt cggaatcagc gcgatgcgtt atcatattga gcaagttcct gagggcaaga
    30901 aactttcctt tagggatatg ctgagcgcta tgactcagat gattgggatg tcttgcttct
    30961 tcaaccgaga aggaaagatg gaaatccgtg atttgaccga gtccaacatc acgattaacg
    31021 ctgacagtta cttcttgcat ggattgacca agagtgaaat cgagtatcag atagctggta
    31081 tcacttgtaa gacggataag aagtctctga cggtcggtat gacaacaggt cggtctttgg
    31141 aacttgataa tgtcttcata acccagagcg ctttaaatga cttgtattac aaactgaaaa
    31201 acctaactta ctatccgtat aatctcaact accaaggaca tttgttactt gaggttgggc
    31261 agtgggtaac cattcagacc aacaagaaag agacttttaa agttcctgtc ttaagtcaga
    31321 gctttatctt taaaggtggt ctgagaggtc gtatcagtgc agatagtaag gctggaaacg
    31381 atacccagta ttcttacgag ggtacgatta ccaagcagat taagcaacaa gatggctttg
    31441 aagcgaaaat ccaagcgcag attgaagcag cagataaaga ttttgaccaa aaggtcgaca
    31501 aaatcaaaaa agactttaac gatcaagtag aactggccaa agccagagct gaagaagtca
    31561 agagagaact gtctgacact atcaatcagc gctttaatag ctttgacaac gggccattga
    31621 aagaagctaa gcgcaaggct gaggaagctt tgcgaaatgc tggcgcaagt agttctcttg
    31681 ctcaggaatc caagcggatt gggctggatt ctgttgctag acttgaagcg tttaagtcgc
    31741 agactacgag cgcacaaacg gctctgtcgg gtgacttgga cgctctgaaa cggactatcg
    31801 cgaatgatat tcgaccgaag caagcacagg ctgaagctga gattgccaag caagttgaag
    31861 cacttagccg gactaaaaat gaactggatg gcgcaagtac cctgcttgca caggaagcta
    31921 agcggattga gctggattct gttgctagac ttgaagcgtt taagtcgcag actacgagcg
    31981 cacaaacggc t
//
LOCUS       DAVHKZ010000025        31091 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000025 DAVHKZ010000000
VERSION     DAVHKZ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31091
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.025"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(74..304)
                     /locus_tag="VVO74_001384"
     CDS             complement(74..304)
                     /locus_tag="VVO74_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU5695399.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            complement(314..1555)
                     /locus_tag="VVO74_001385"
     CDS             complement(314..1555)
                     /locus_tag="VVO74_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU5695400.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDLLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVIFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSLVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(1577..1729)
                     /locus_tag="VVO74_001386"
     CDS             complement(1577..1729)
                     /locus_tag="VVO74_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695401.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(1750..2028)
                     /locus_tag="VVO74_001387"
     CDS             complement(1750..2028)
                     /locus_tag="VVO74_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEU5695402.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(2021..2284)
                     /locus_tag="VVO74_001388"
     CDS             complement(2021..2284)
                     /locus_tag="VVO74_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU5695403.1"
                     /translation="MSKMSMSIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(2386..6777)
                     /locus_tag="VVO74_001389"
     CDS             complement(2386..6777)
                     /locus_tag="VVO74_001389"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU5695404.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VDKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     GAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(6881..8962)
                     /gene="fusA"
                     /locus_tag="VVO74_001390"
     CDS             complement(6881..8962)
                     /gene="fusA"
                     /locus_tag="VVO74_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU5695405.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(9387..9857)
                     /gene="rpsG"
                     /locus_tag="VVO74_001391"
     CDS             complement(9387..9857)
                     /gene="rpsG"
                     /locus_tag="VVO74_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU5695406.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(9877..10290)
                     /gene="rpsL"
                     /locus_tag="VVO74_001392"
     CDS             complement(9877..10290)
                     /gene="rpsL"
                     /locus_tag="VVO74_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU5695407.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            10707..14504
                     /gene="spuA"
                     /locus_tag="VVO74_001393"
     CDS             10707..14504
                     /gene="spuA"
                     /locus_tag="VVO74_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU5695408.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWHLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDLAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRNESVENSSKENIPATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            complement(14604..15653)
                     /locus_tag="VVO74_001394"
     CDS             complement(14604..15653)
                     /locus_tag="VVO74_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEU5695409.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SDGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHIPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            15710..15847
                     /locus_tag="VVO74_001395"
     CDS             15710..15847
                     /locus_tag="VVO74_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695410.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTNEVSNHTYGKATLTWFEEI
                     F"
     gene            complement(15924..17732)
                     /gene="glmS"
                     /locus_tag="VVO74_001396"
     CDS             complement(15924..17732)
                     /gene="glmS"
                     /locus_tag="VVO74_001396"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU5695411.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYFEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(17925..19304)
                     /gene="bglA"
                     /locus_tag="VVO74_001397"
     CDS             complement(17925..19304)
                     /gene="bglA"
                     /locus_tag="VVO74_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU5695412.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHCPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            complement(19404..21257)
                     /locus_tag="VVO74_001398"
     CDS             complement(19404..21257)
                     /locus_tag="VVO74_001398"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU5695413.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(21270..22529)
                     /gene="rseP"
                     /locus_tag="VVO74_001399"
     CDS             complement(21270..22529)
                     /gene="rseP"
                     /locus_tag="VVO74_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU5695414.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTVLPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPKDSQG
                     RYLLGVQPGGKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(22551..23354)
                     /locus_tag="VVO74_001400"
     CDS             complement(22551..23354)
                     /locus_tag="VVO74_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU5695415.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(23363..24121)
                     /locus_tag="VVO74_001401"
     CDS             complement(23363..24121)
                     /locus_tag="VVO74_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU5695416.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(24352..24816)
                     /locus_tag="VVO74_001402"
     CDS             complement(24352..24816)
                     /locus_tag="VVO74_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEU5695417.1"
                     /translation="MAAGSVRNFIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLE
                     KKLREDFPQYQWELKNQVYMHQHSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFE
                     LYAPYGLEDILNFQVRPTPHFLENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            complement(24905..25876)
                     /gene="ruvB"
                     /locus_tag="VVO74_001403"
     CDS             complement(24905..25876)
                     /gene="ruvB"
                     /locus_tag="VVO74_001403"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU5695418.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            26037..26129
                     /locus_tag="VVO74_001404"
     CDS             26037..26129
                     /locus_tag="VVO74_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU5695419.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            complement(26944..27360)
                     /locus_tag="VVO74_001405"
                     /pseudo
     CDS             complement(26944..27360)
                     /locus_tag="VVO74_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(27372..28064)
                     /locus_tag="VVO74_001406"
                     /pseudo
     CDS             complement(27372..28064)
                     /locus_tag="VVO74_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144882.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(28364..30865)
                     /locus_tag="VVO74_001407"
     CDS             complement(28364..30865)
                     /locus_tag="VVO74_001407"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU5695420.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDTSKPKFYALDMFPYPS
                     GVGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDISREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
BASE COUNT         9056 a         7283 c         5941 g         8811 t
ORIGIN      
        1 cagtgctttg agcaacctgc ggctagtttc ctagtttgct ctttgatttt cattgagtat
       61 cagatttagg aaattaactt cctcgtctcc aaaaaatagc taagacaatc atggcaccta
      121 aaacagctgg gataatagct gttcctgata aaactggccc ccaagttcca aagagcaagt
      181 gacctagaaa ggctccgatc caaccgagaa acatttttcc aaaacatccc attcgctctc
      241 cacgattggt catagcacct gctaaaaatc ccactaggag accaacgaac atacttccta
      301 acatattatc tccttaattt gcccaattcc cattacggaa aagaggtacc cgcgttccat
      361 cctcacgaat accatcgata tccatttggt tagaaccaat cataaagtct acgtgaacat
      421 ctgaacggtt aagccctgca gcttcaagct cctcttcgct catctccgct ccatcaacaa
      481 ggctagtcgc ataggctgca ccgatagcca agtggtttga cgcattttca tcgaaaaggg
      541 tgttaaagaa ggtaatgcct gactgagaaa ttggacttgg atctggtacc aaggcacatt
      601 cacccaaggc acgcgcaccc gcattttcaa agacaaggtc tttcataacc tgatcaccct
      661 tctcagcagt gatatctacg atttgtccat ccttaaagat caccttaatg ccttcaatga
      721 tatttccgtt gtagctaagc ggttttgtag aagtgacata accatctgca cgacggaagt
      781 caggcgctgt gaagacctct tctgtcggca tatttggcaa gaatccttcg ccctgtgcat
      841 tgacagcacc agctgattcc caaacgtggt tctttggcaa accaagtgtt aaatctgttc
      901 ctggcgctgt gtagtgaagg gctgaaaatt gctccttatt aagcatatcg gccttgctct
      961 tgagaatggc tgcatgctct tcccaggcct taacaggatc tgcttcgtag acacggcaag
     1021 ttttgaagat ttggtcccaa aggagatcga ctgcttcttc gtcgctcgca gcatttggga
     1081 agactttctt agcccactca agtccagcag cggctgctac agtccagcta accttgttag
     1141 attgagttgc gattcgcatt ggcttcatgg caagtcccat agctttagca gaagctgaaa
     1201 gcttgtcagc gtccactccg ttcaaggcac ctggatcaga tgaacgaact ccaagacggc
     1261 tagccttgtt ctccaagaga tagttcatct cagcaatctt gtattctggc acattgtcca
     1321 aacgctccat cggggcatgg aggaatttct cacggttaat cacatcatct gtccactgaa
     1381 cgatgacctc atgcgcaccc aaggcataag cttctttcac gattagatgt gccaattcac
     1441 gttgctccac atcaatagag agagccaaag tgtgaccagg ttgcacgtta attccgttcg
     1501 caaccaacaa tttcgcatat ttttctagat tttctttaaa atttggtaaa accatcctgt
     1561 tttctctttt ctatttttat ttttctttca aagcagaaaa gattcctgct aaagcaatag
     1621 cacctgacaa gagtgctgtc gataaaagaa ttgtacgatc agcaagttct aattgatatt
     1681 caaatacctt cttagccggc ttatcttccg caaatattct tagtttcatg agaaccccct
     1741 taaaatagat taaaataaat cactgtgact gcctgtcctc agcaaattta aaatcaattc
     1801 cgacttatct actttataaa ccaaaagcca atctggctgg gtatggcatt cacgaactcc
     1861 ttgaaaatgc ttggatgccg tcaatgaatg atcacgatat ctggcaggat gttctttttc
     1921 ttgaaccaga aaattcaaaa cttcttctaa taattctgcc ttcaaaccac gcttcatagc
     1981 caacttaaaa tcttttttaa actgtttatg ataacgaatc ttaagcacgt aagtcctcca
     2041 tcaaatctga gactgattca aaagactggc tcatattacg attttggtct aaatccgtta
     2101 acacttggag caacttccga ttttcgtcta gtctaacatc aaaaggtaat ccctgatatt
     2161 gaattgcctg acgaaggaaa atattaatag ctgttgtcat atccattccc agattactaa
     2221 acacctgttg ggcctgctcc ttaacctcac tatccagacg gatgctcata ctcatctttg
     2281 acatactctc accctctttc catagactat tttaacaaaa aagaaagcta atgtaaatct
     2341 attggatata cgttagcctc ttctaataga ttattaagca attttttaaa acaactcatc
     2401 aaacaaactc aactggttat cctctggcat atttccaaga atacccatct catccatctt
     2461 ttcaaccaag gttgatgaga gtccaccacg cttgcgtagt tctgttttag agaggaattc
     2521 tccctcttca cgcgcccgca ccagttgctt ggcaacgttc tctcccagac catccattgc
     2581 tacaaatggt gggataaggg tatccccgtc gatgaggaac tctgtcgcct gactacggta
     2641 gagatctaat ttgccaaact tgaaacctcg ttcccacatc tcattgacaa tctcaagagt
     2701 tgtatagaga tcgatttcca cattagaggc ttcattgttc ttccgttttt cagagatttc
     2761 ttccattctg cgcttgatgg cctccaagcc cgcacccatg gtcttgatat caaaagcctt
     2821 agcacgaatg gagaagtaag cacagtagta ataaatagga tggtgaacct tgaagtaagc
     2881 tacacgcaag gccatcataa cgtaggctgc cgcatgggcc ttagggaaca tgtacttaat
     2941 tttcccacag gattcgatat accactctgg caccttatta gccttcatgg cttcgatata
     3001 gccatttctc tcctcttctg aaatctttag ccacaaaccc ttacgtaccc gttccataat
     3061 ggtaaaggcc atcttaggtt ccagacccgc atgcatgagg taaaccatga tgtcgtcccg
     3121 acaaccgata acagtcgata ggtccgctat tccttgctta atcagatcct gagcattccc
     3181 caaccaaacg tcagtaccgt gggacagacc agacagctga agcaattccg caaaggttgt
     3241 cggatgggtt tcgtctacca ttccacgtac gaaatttgtt ccaaactctg gaatccccaa
     3301 catacccgta ggcgttccaa tttgttcagg tgttacccct agcacatcag tcccagaaaa
     3361 gagtgccatc acgccttcgt catccatagg aatttcatta gggtcaatac cagacaaatc
     3421 ctgaagtttt cgaatcatgg tcggatcatc atgtcccagt acatcgagtt tgaggacgtt
     3481 ctcatcgata tcgtggaagt taaagtgagt ggtctgccat tcagccgtga catcatctgc
     3541 tggatactgg acaggcgtaa aatcgtagac atccatgtag ttcggaataa caacgattcc
     3601 ccccgggtgt tggcctgttg tccgcttgac acccgccgct ccttgagcga ggcgttctac
     3661 ttctgcatca cgataaaact tgccataatc tcgctcgtaa cccttgacaa atccataggc
     3721 agtcttggca gctaccgtac caaccgttcc cgcacggaag gcatattctt caccaaagat
     3781 atcacgcaca tccaagtggg cgctaggctg atcttctccc gagaagttca agtcaatatc
     3841 aggaacctta tccccatcaa agccaaggaa ggtctcaaac ggaatatcct gtccgttttt
     3901 actgagtttg tgaccacagt ttggacagtc cttatggggc atatcaaatc ctgaaccgta
     3961 cgaaccatct gtgataaact cactgtactg acactgacca cagacatagt gaggagagag
     4021 aggattgacc tccgtaatcc caatcatggt cgcaacgaaa ctagatccga cagacccacg
     4081 agaaccaacc aaataacccc gttcattaga acgttgcacc agcatctgcg atgccagata
     4141 aatcacagca aatccattcc ccagtatgga tgttaattct ttttcaatcc gcaaatcaac
     4201 aatatctggc agcggatttc cataaatctc aaaagctttc ttataggtca actcagcaac
     4261 tgtttcttca gccttgtcga tgaaaggcgt atacaagtca cccttaacga cttcaacggg
     4321 ttcaaatatt tctgccaagg cattagtgtt ttcaataacc agtttacgag ccagttcctc
     4381 tcccaaaaag gcaaattcat ccaacatctc attagtcgtt cgaaaatgag cctttggaag
     4441 tggtgctggt tgggcatgtt caccatgacc gatagttcga ttaatcatcg caccctgtcc
     4501 caaactacgg acaataattt cacgataaat ctcttcttcc ggttcgatat agtgaacatt
     4561 tcccgtagcc agaacaggct tgccaaggcg atctccaacc tctatcaaac tcttgataat
     4621 ggtctggagt tcctccatat ccttgacctg ctctttggca atcaagggcg catagatagc
     4681 cggtggcatg acctcgataa agtcataata cttggccacc tcaaccgccc catccacacc
     4741 ttgagaaacg accacgtcaa aaacttcacc ctctgaacag gctgaaccta aaatcaagcc
     4801 ctctcgatgg gcatctagaa ccgttctcgg aatccgtggc actccttcaa aatacttggt
     4861 attagacaag gaaaccagct taaagatatt ttttagacct acctgattct tgacatagat
     4921 ggtcgcatgc ttgatccgag cttttttgta agaatctgga ctgattagat caatgttgag
     4981 tctagctaaa tcggtcacac catgtttttc tgctacctct ttgataaaga tgaaaagcag
     5041 acgaccagtc gcttccgcat cgtaattggc catgtggtga tgttccaagg ccacaccaaa
     5101 acgcttggtc aaaggcccca aaccatggcg tttatactca ggatagaggt ttctagcaaa
     5161 ctccagcgta tcaataactg gctgactaat ctttggaaga ccatgacgct cataattagc
     5221 attcataaag ccaacgtcaa aggtagcatt gtgggcaact aggaccgtat ccttgcaaaa
     5281 ttcttggaat tcttgcaaaa cttgttctag tggtttggca tttttgacat gatcatctgt
     5341 aattccagtt aactctgtag taaaggctga caagggatgc ccaggattga taaattcatc
     5401 aaattcagca ataacattcc ccttgtacat cttagaggcc gcaacctgaa tcaagtcatt
     5461 atagatagct gaaagtcccg tcgtttccac gtcaaagacc acgtaggttg cttctgacaa
     5521 gtccatctcc acttcgttat agacgatagg gacacggtcc tccacgatat tggcttccat
     5581 cccatagatc agctggattc ccgctttctt agccgcctta tagccatgtg gaaaggactg
     5641 gacattccca tggtccgtga tagcaaccgc cttgtgtccc cacttagcag ctgttgcaac
     5701 aatctcttcg acctctggca aagcatccat agtcgacatg ttagtatgag catgaaactc
     5761 aacccgacgc tcaccttctg gcatcaaatc cttccgctca tagtgaacaa cttcctgcag
     5821 atcctgtacg ttcatagtca aatcgcgtgt gaagttattc atctccacat tccctcgaac
     5881 tcggagccaa gaattcttct tgatgagatc aaacttctgg gcctcttcct cgtttttaac
     5941 ccacttttgc atagaaaaac ttgaagtgta gtccgtcatt ttaaagttga ttaaaacacg
     6001 acctgttcta gtcacttttt gctccacatc aaaaacaacc ccttcaaata ccagacgatt
     6061 ttcctctgtc gtcacttcga tcataggagt aatctccgcc ttatccagct tgggtttagc
     6121 tgcagctttt ttcgcttgaa aatcaaagac tggtttctct tccgctggag gaggtgccat
     6181 ctgctccagt tgttccatag cacggagcgc ttcctcattg gcagcttgaa caatctgctc
     6241 attttcagca tgaaaggcct cttcctgctc ttgggtcagg acatcattct tatcgacttg
     6301 acagttaaaa gttggaaaac caaacttttc aagttgtttg gctaaattag gaagatgatt
     6361 cttcttaaaa tgttccttat caatcgcctc agatccttca ataaatagct gattaccctc
     6421 agcacgaact tgcaaatttt gataaaggga cttaaaacct tgactagcac atggaccttc
     6481 agagaaagcc tccctatagt aggactgcaa gagctgattt gaaaattctt gagaccgagc
     6541 cttaatttca aaaacagctt tattgcctgt cttagaaaat tcttcgctca aacctttctt
     6601 taattctaaa aagatttcaa tcggtaaaat attagaaaat acgaaatgaa actcccatac
     6661 cttactaatt ttatgaacca caactcgctc aatattggcc tgtgctaaag caggagcctg
     6721 tctcatttca gcaggcatcc ccaattgatt catcaaaatt tcaaaactat ttgacattca
     6781 ttttcctcac attattcttc tactatttta ccatatttag aggtattttc taaagacaaa
     6841 aggaagccac taagtgactt ccttctagag tgaggacgga ttagtcttca cctttatttt
     6901 tcttaataat ttcttcttgt actgacttag gtacatcttc gtagtggtca aataccatca
     6961 tgaatgtacc acgtccttga gatgcagaac gaagaactgt tgcgtaaccg aacatttcag
     7021 caagtggaac gtaagcacga acgatttggc tgttaccgtg tgcttccata ccatctacac
     7081 gtccacgacg agcagttacg tgacccataa catcaccaag gttttcttct ggaacagtga
     7141 ttgttacaag catcattggt tcaaggatag ctggttgtgc tgatttagca gcttctttaa
     7201 gggaaagtga agccgcaatc ttgaaggcag tttcagatga gtcgacatcg tgatatgaac
     7261 catcataaag cttagcttta acgtcaacca ttgggtaacc tgcaagaaca ccgttagcca
     7321 tagattctac caaacctttt tcaaccgctg ggataaattc acgaggaacc acaccaccga
     7381 cgattgcgtt ttcgaattcg aatcctttac cttcttcgtt tggagtaaat tcaatccaca
     7441 catcaccgaa ttgaccttta ccaccagact gacgtttgaa gaatccacgt gcttgagtag
     7501 aagcgcggaa tgtttcacgg taagatactt gaggcgcacc tacgttcgct tcaactttga
     7561 actcacgacg catacgatca acaaggacgt caaggtgaag ttcacccata cctgagataa
     7621 ctgtttcacc agtttcaacg tttgtttcaa cgcggaatgt tggatcttct tcagccaatt
     7681 tttgaagggc gatacccatc ttgtcttggt cagctttaga ttttggctca accatcaatt
     7741 ggataactgg ttctggaacg ttgattgact caaggatgat tttagatttt tcatctgtca
     7801 atgagtcacc agttgtagta tctttcaaac caacggcagc agcgatatca cctgagtaaa
     7861 cagtgtcgat ttcttgacgg ctgttagcgt gcatttgaag gatacgtccg atacgttcac
     7921 gtttaccttt agaagtattc aatacgtatg aacctgattg aagaacacct gagtaaacac
     7981 ggaagaatgt caaacgacct acgaatgggt cagtcatgat cttgaaggca agagctgcaa
     8041 atggctcttc gtcagatgct ggacgagttt cttcagcgtc tgtatctggg ttaatacctt
     8101 tgattgctgg gatgtcaagt ggacttggaa ggtagtcgat aaccgcatca agcatcaatt
     8161 gaacaccttt gtttttgaag gctgaaccac acaatactgg gaagaattca acgttgatag
     8221 tcgctttacg gataccagct ttcaattctt cgttagtgat ttcttcacct tcgaggtatt
     8281 tcatcatcaa ttcttcgtca gtttcagcaa ctgcttcaat caatttttca cggtattctt
     8341 gagcttggtc aaggtattca gctgggatgt cttcttcaag gatatccgta ccaaggtcgt
     8401 tagtatagat ttcagctttc atcttgatta agtcaatgat accacggaag tcatcttcag
     8461 aaccgattgg caattggatt gggtgtgcat ttgcttgaag gcgatcgtga agtgtgctta
     8521 cagagtaaag gaagtcagca ccgattttgt ccattttgtt ggcaaatacg atacgtggaa
     8581 ctccgtactc agttgcttga cgccaaactg tttcagtttg aggctcaaca cctgattgtg
     8641 agtcaagaac ggtaaccgca ccatccaata cacgaagaga acgttgtact tcgattgtga
     8701 agtccacgtg tcctggtgtg tcgatgatgt ttacgcggtg gttgttccat tgagctgttg
     8761 tcgcagcaga tgtgatcgtg ataccacgtt cttgctcttg ctccatccag tccatttgtg
     8821 acgcaccttc gtgagtttca ccgattttgt ggattttacc agtgtagtaa agaatacgct
     8881 cagtagttgt tgttttaccg gcatcgacgt gagccatgat accgatatta cgagtttttt
     8941 caagtgaaaa ttcgcgtgcc atgaggtttg tttctcctat ttatttttga tttctattct
     9001 attataacac gattttaata aaaacggata ggcaggacct acccgttctc aatgttttca
     9061 tgctattgtt ggtttcaact tacgagatgg taagctgagt tatagctaat actaatcgat
     9121 ttagctaatt tgaacccggg ctaaagttag ttagccgatg tgagctggaa cgggatgctg
     9181 cgtgaaaaag ataaaactcc ttgtattcgt cgaatactgc gtcagtttcc tattttcacc
     9241 ttgcatcctt accgttccta gcatcatgat ttagttgagc tcaagctaaa agtctggaga
     9301 aaaagatgaa tctcattggt tgcaaccgca acctgcttcg attccctatt ttctctggga
     9361 ctttcttaac gctttcgcat cctatcttac caacggaagt gtgcgaatgc acggttagct
     9421 tcagccatac ggtgagtatc ttcacgtttc ttaactgctg caccagtgtt gttagcagca
     9481 tccaagattt cttttgcaag acggtcttgc attgtgtgtt caccacgaag acgagcgatt
     9541 gttaccaacc aacgaagtcc aagtgttgta cgacgttctg gacgaacttc aactgggact
     9601 tggtagttag aaccaccaac acgacgtgca cgtacttcaa gtacaggcat gatgttttcc
     9661 atagctgttt caaatacttc aagtgcatcg ttgccagtag cttctttgat ttgctcaaaa
     9721 gcaccgtaaa cgattgaagc agcagtacca cgtttaccat caagcataac gcggttgata
     9781 agacgagtaa ctagttgtga attgtatagc ggatctggca atacgtcacg ttttggagct
     9841 ctatttttac gactcatttc tctttatccc ctttccttat gcttttggac gtttagtacc
     9901 gtatttagaa cgaccttgtt tacgatcgtt aacacctgca gtatcaagtg caccacggac
     9961 gatatggtaa cgtacccctg gaaggtcttt tacacgtcca ccgcgaagaa gcaccacgct
    10021 gtgctcttgc aagttgtgtc cgatacctgg gatgtaggca gtaacttcga taaggttgct
    10081 caaacgtaca cgagcgaatt tacgaagggc tgagttaggt tttttaggtg tcattgttcc
    10141 aacacgagtt gcaacaccac gtttttgtgg tgaagaaacg tttgtttgaa cttttttatg
    10201 actattgtaa ccaacgttca aagctggtga tttagatttt tctacttttg atttacgcgg
    10261 tttgcgaacc aattggttaa ttgtaggcat ctacattctc ctgtgttttt ttatttttgg
    10321 tgatgataca cttggtgaca gatatcatct gtgtgtactt ttgcaacatt tgtcagcacg
    10381 tccctgtaca ctcttgagag accaaaagta aaaagtaccg tctattattg taacaaaatt
    10441 ttcccttgtt tgtcaagata tttttctttt ttattggtaa tgttagagat caatttctga
    10501 ataaaaatag ctgggaacac atcatcttcc taataatacg gcttggctta tgtgacattt
    10561 ttatctccgt catttatact gatatataaa atagtacaga aaacttctca aaagtaagaa
    10621 tttttttcac aaatcaaaga aaacgcttgc atattgtttt actacatgct atactgatat
    10681 agaaatttat tgattggaga atcattatga gaaaaacacc atctcacact gagaaaaaaa
    10741 tggtctacag catccgttcc ctcaaaaatg gaactggttc tgtccttatc ggcgcaagcc
    10801 ttgtcttgct tgccatggct acaccaacta tctcatccga cgaaagtaca ccaaccacta
    10861 acgaacccaa caacagaaat acaaccaccc ttgcccaacc tcttactgat acagcagctg
    10921 gctctggtaa gaacgaaagt gatatttctt cacctagaaa tgcaaacgct tccctagaga
    10981 aaacagaaga aaaacctgca acagagccaa ctacttctac tagtccagta acaactgaaa
    11041 ctaaggcaga agagcccatc gaagataact acttccgtat ccatgtcaaa aaacttcctg
    11101 aagaaaacaa ggatgctcaa ggactatgga cttgggacga tgttgaaaaa ccatctgaaa
    11161 actggccaaa cggagctttg tccttcaagg atgccaagaa agatgactac ggctattacc
    11221 tagatgtcaa attaaaggga gaacaagcca agaaaattag cttcctcatc aacaatacag
    11281 ctggaaaaaa tctaaccggc gataaatctg tagaaaaact agttccaaaa atgaacgagg
    11341 cttggttaga ccaagattac aaggttttct cttacgagcc acagcctgca ggaactgttc
    11401 gcgtcaacta ctaccgcaca gatggcaact atgacaagaa atctctctgg tactggggag
    11461 atgtgaaaaa tccaagtagc gctcaatggc ctgacggaac agactttacg gctacaggca
    11521 aatatggccg ctatatcgac attcctctta atgaagccgc aagagaattt ggatttttat
    11581 tactagatga gagcaaacaa ggagacgacg tgaaaatccg taaagaaaat tataagttca
    11641 cagatttgaa aaatcatagc caaattttcc taaaagacga tgatgaatcg atttacacaa
    11701 atccatacta tgtccatgat atccgtatga caggagccca acacgtaggc acttctagca
    11761 ttgaaagtag cttttcaaca cttgtcggtg ctaaaaaaga agatatcctc aaacactcca
    11821 acatcactaa tcacctagga aacaaggtaa ctattaccga tgttgcaatc gatgaagctg
    11881 gtaagaaagt gacctacagc ggagatttct ctgacacaaa acatccttat actgttagct
    11941 acaattccga ccaattcact accaaaacaa gctggcacct gaaagatgag acatacagct
    12001 atgatggcaa actgggagct gacctaaaag aagaaggaaa acaagttgat ttgacccttt
    12061 ggtcaccaag tgctgataag gtttctgttg ttgtctacga caagaatgac cctgacaaag
    12121 tagttggaac tgtcgctctc gaaaaagggg aaagaggaac ttggaaacaa actctagaca
    12181 gcacaaacaa actcggaatc acagatttca ctggctacta ttatcaatac caaatcgagc
    12241 gtcaaggtaa aactgttctt gcactcgatc cttacgctaa atctcttgct gcttggaata
    12301 gcgacgatgc caagattgac gatgcccata aagtggctaa agccgccttt gtagatccag
    12361 ctaaactcgg acctcaagac ttgacttatg gtaagattca caatttcaag actcgtgaag
    12421 acgccgttat ctacgaagct catgtgcgtg acttcacttc agatcctgcc attgcaaaag
    12481 acttgaccaa accatttggg acttttgaag ccttcattga aaaactagac tatctcaaag
    12541 acttgggtgt aacccatatc cagctccttc cagtcttgtc ttactacttt gtcaatgaat
    12601 tgaaaaacca tgaacgcttg tctgactatg cttcaagcaa cagcaactac aactggggat
    12661 atgaccctca aaactacttc tccttgactg gtatgtactc aagcgatcct aagaatccag
    12721 aaaaacgaat cgcagaattt aaaaacctca tcaacgaaat ccacaaacgt ggtatgggag
    12781 ctatcctaga tgtcgtttat aaccacacag ccaaagtcga tatctttgaa gacctagagc
    12841 caaactacta ccactttatg gatgccgatg gcacacctcg aactagcttt ggtggtggac
    12901 gcttggggac aacccaccat atgaccaaac ggctcctagt tgactctatc aaatacctag
    12961 ttgataccta caaagtggat ggcttccgct tcgatatgat gggagaccat gacgccgctt
    13021 ctatcgaaga agcttacaag gctgcacgcg ccctcaatcc aaacctcatc atgcttggtg
    13081 aaggttggag aacctatgcc ggtgatgaaa acatgcctac taaagctgct gaccaagatt
    13141 ggatgaaaca taccgatact gtcgctgtct tttcagatga catccgtaac aacctcaaat
    13201 ctggttatcc aaacgaaggt caacctgcct ttatcacagg tggcaagcgt gatgtcaaca
    13261 ccatctttaa aaatctcatt gctcaaccaa ctaactttga agctgacagc cctggagatg
    13321 tcatccaata catagcagcc catgataact tgaccctctt tgacatcatt gcccagtcta
    13381 tcaaaaaaga cccaagcaag gctgagaact atgctgaaat ccaccgtcgt ttacgacttg
    13441 gaaatctcat ggtcttgaca gctcaaggaa ctccatttat ccactccggt caggaatatg
    13501 gacgtactaa acaattccgt gacccagcct acaagactcc agtagcagag gataaggttc
    13561 caaacaaatc tcacttgttg cgtgataagg acggcaaccc atttgactat ccttacttca
    13621 tccatgattc ttacgattct agcgacgcag tcaacaagtt tgactggact aaggctacag
    13681 atggtaaagc ttatcctgaa aatgtcaaga gccgtgacta tatgaaaggt ttgattgccc
    13741 ttcgtcaatc tacagatgcc ttccgactta agagtctcca agatatcaaa gaccgtgtcc
    13801 acctcatcac tgtcccaggc caaaatggtg tggaaaaaga ggatgtagtg attggctacc
    13861 aaatcactgc tccaaacggc gatatctacg cagtctttgt caatgcggat gaaaaagctc
    13921 gcgaatttaa tttgggaact gcctttgcac atctaagaaa tgcggaagtt ttggcagatg
    13981 aaaaccaagc aggatcagtc ggaattgcca acccgaaagg acttgaatgg actgaaaaag
    14041 gcttgaaatt gaatgccctt acagctactg ttcttcgagt ctctcaaaat ggaactagcc
    14101 atgagtcaac tgcagaagag aaaccagact caaccccttc caagcctgaa catcaaaatg
    14161 aagcttctca ccctgcacat caagacctag ctccagaagc tagacctgat tctactaaac
    14221 cagatgccaa agtagctgat gcggaaaata aacctagcca agctacagct gattcacaag
    14281 ctgaacaacc agcacaagaa gcacaagcat catctgtaaa agaagcggtt cgaaacgaat
    14341 cggtagaaaa ctctagcaag gaaaatatac ctgcaacccc agatagacaa gctgaacttc
    14401 caaatacagg aatcaaaaac gaaaacaaac tcctatttgc aggaatcagc ctccttgcgc
    14461 tccttggtct cggtttctta ctaaaaaata aaaaagagaa ctaaactagc cctcctatag
    14521 aaaaatcccc caagcattat agctcggggg attaattttc gtacaatatt tgttgtccta
    14581 ataaacttga ttaggatttt ttattaagcc tctttcatag caaaataagc tcgtactttt
    14641 ggtgcaactt gtgttccgaa gagttcaata gctctcagaa cctggtcatg aggcatagaa
    14701 ccaagcggta tatgaagcat gaagcggtcc aatcctaaat cctctatcat gcgaatcaat
    14761 ttttcggcca cctgatctgg attgccaaca aacatggcgc catttggccc tacctgctcc
    14821 aaatattgct cataacgcaa ttcctgccag tgcggacggt ctttggaaat agcatccacc
    14881 acttgcttag tcggatggaa ataatctttc accgcctgct caccatcttc cgcaatccac
    14941 ccccaagaat gggctcccac tttcaagtct ttgtcagcat ggcccgcttc gcttccaatc
    15001 tcacgataag cctgaatcaa ctttttaaaa taacgtggat taccaccaat aatagcatat
    15061 acaatcggta gaccagcctg agcaatcttc actgttgatt cgacatgacc acctgtagct
    15121 atccacaagg gcaatttgtc ctgaactgga cgaggataaa cttctttacc agcaatcgtt
    15181 tgagtcaatc gaccttgcca gtctaacttg gtcttttcat tgactaactg aagcaagtct
    15241 aatttctcat caaaaagaga gtcgtagtct ttcaagtcat aaccaaacag agggaaagat
    15301 tccgtgaaag agccccttcc agccataatc tccgatcgtc catctgacaa agcatcgata
    15361 gtggcatact gttggaacaa acgaatcggg tccatgcttg acagaatgct gactgcactg
    15421 gtcaaacgga ttttcttggt attgactgcc ccagcggcca ggacaatctc tggggctgat
    15481 actgcaaaat ccgcccgatg gtgctcgcca atcccatata cgtccaaacc aaccttgtca
    15541 gccagctcaa tctctgccac caactggcga atgcgttcag catgactgta agtttgtcca
    15601 gtcccttcaa gctccgttat ttccccaaat gttgaaattc ccaattctac cattgtgatt
    15661 ctccttgtct atctctgtac ttcaatttga aaaattattc taatactcaa tgaaaatcaa
    15721 agagcaaact aggaagctag ccgcaggttg ctcaaaacag tgttttgagg ttgtggatag
    15781 aactaacgaa gtcagtaacc atacctacgg caaggcgacg ttgacgtggt ttgaagagat
    15841 tttctaagag tataacacga atcttgagta caagcaacca atttgctcac aagaaaaagc
    15901 ctagataact agactttttt agcttattct accgttactg acttggcaag gttacgtggt
    15961 ttgtccacat cgaggccacg gtggagggtt gcaaagtaag cgactaattg cgtcggtacg
    16021 accattgaaa ttggtgagag gtatggatgt acggtcgtaa ggacgatatc gtcggtatct
    16081 ttggctacat tctcttctgc gatagtgagg actttggcac cacgggctgc gacctcttgg
    16141 atatttccac gagtatggtt ggcaagaact ggatctgaca agagagccaa aacaggcgtt
    16201 ccttcttcaa tcaaggcaat ggttccgtgc ttgagttctc ctgccgcaaa accttcacac
    16261 tggatataag aaatctcttt gagtttgaga cttgcttcca tggctacgta gtaatcttga
    16321 ccacgtccga tgtaaaaggc gttacgagtt gtttcaagaa gttcacgaac cttggcttca
    16381 atggtttctt tctctgaaag agttgattcg atagactgag ctacgattga caattcatga
    16441 accaggtcaa aggcttgcgc tttagcatta ccatttgctt ctccgactgc ttttgcaagg
    16501 aaggcaaggg ctgcgatttg cgctgtatag gctttagttg atgccacggc aatttcagga
    16561 cctgcgtgaa ggagcatggt atagttggct tcacgtgaga gggttgaacc tggaacgttt
    16621 gtcactgtta agcttggaat tcccatttca ttagccttga ccaaaacttg acgactatcc
    16681 gctgtttcac cagattggct gataaagatg aagagtggtt tcttgctgag aagtggcata
    16741 ccgtagcccc actcagatga gattccaagt tcaactggtg tatctgtcaa ttcttccaac
    16801 attttcttag aagcaaatcc tgcatggtaa gatgttccag ctgcaaggat gtagatgcgg
    16861 tctgcgtctt gaacagcctt aatgatatct gggtctacga caacttgacc agcctcatct
    16921 gtgtaggctt ggatgagttt ccgcataaca gttggttgct cgtcaatttc cttgagcata
    16981 tagtaagggt aagttccctt accgatatct gacaagtcaa gttcagcagt gtagctagca
    17041 cgctcacgac gatttccatc atagtcttga acttccacac tatcagcctt gacgattacc
    17101 aactcttggt catggatttc catgtattgg ttagtttcac gaatcatagc catggcgtct
    17161 gagcagacca tgttatagcc ttctccaaga ccaatcaaaa gtggtgattt atttttagct
    17221 acgtagatga cttcaggatc ttgtgagtca accaaggcaa aggcataaga accacggatg
    17281 atgtgaaggg cttttttgaa ggcttcaaga actgagagcc cttcttcttc cgcaaatttt
    17341 ccaatcaaat gaacggctat ttcagtatct gtctgcccct tgaagtggtg acctgcaagg
    17401 tattcttcct tgatttcaaa gtagttctca atcaccccat tatgcaccaa gacaaaacgt
    17461 tctgtctcag agcggtgtgg gtgagcattg tcctcagttg gttttccgtg agtagcccaa
    17521 cgagtatgtc cgataccagt tgttccctca acaccagctg tcttggcaga caattctgca
    17581 atacgaccaa cagccttcac caaatggtta tcagcaccat ctaggacaaa aattcccgca
    17641 gaatcatagc cacggtattc aagcttttca agcccttgaa tcaaaatatc agttgcattt
    17701 gtgtttccaa caacaccaac aattccacac atagtatata cgacacaggc aagctgtgct
    17761 ttctccttaa aattggtata gtctaattca tcttttatag aatcagcaaa aacagtatat
    17821 acttgtttct ttcacttgtc aagagtaaaa attggtatag ttcaaattaa gctcctgtaa
    17881 gcataaaaac tctgaccgat tgggataatc agtcagagtc ctttttaaaa tccattatta
    17941 tcgcttaatt ctttgaacca gtggcctgat ttcttcagac gacgttcttg cgtttccaag
    18001 tctaattcga ccaaaccata gcgattttta tagctgttga gccatgacca gcagtcaata
    18061 aaggtccaaa tcaagtagcc cttacagttg gcaccatctt caatggcacg gtgaagttca
    18121 cgaagatgac cttttacaaa gtcaatacgg taatcatctt gaatcattcc atcttgacgg
    18181 aatttttctt ccccttcaac acccatacca ttctcagtca acatccactc aatattgcca
    18241 taattttcct tgatattttg ggcgatgtca taaatccctt gctcataaat ctcccaacca
    18301 cggtgagaat tgattttacg tccaggcatc acataaggct cgtaaaaatg ttctggtaag
    18361 agtggactat ctggatgctt agcaaatcga ggagccataa cacgcaaagg ttgatagtag
    18421 ttcacaccaa ggaagtccac cgtattatca cgaatgagtt ccaactcttc ctctgtagca
    18481 tcaggtaaaa gaccgtgttc atgcaagatt tctaccaact cctgtggata agtccccaag
    18541 acagatggat ctaagaaaga ttgggcctga aaaagggccg caatacgagc tgccttgaca
    18601 tcagcaggat gctggctacg tggataagcc ggtgtcaagt tgaggacaat cccaatcttg
    18661 gaatcaggca aaagttcatg gcaagcctta acagcccggc tgctggccaa ttgtgtatga
    18721 taggctacct taacagctgc ctctgcatcc accttatgtg gacaatgggc atcataaaaa
    18781 taaccaaatt ctacaggaac gatgggctcg ttaaaggtaa tccattgatc cactaaatct
    18841 ccataagtct caaaacaaaa acgagcatag tcttcatagg ctgagactgt cgccttattt
    18901 tcccaaccat caccatcctc ttgaagggca aaaggtaaat caaaatgata gagattgact
    18961 aacagacgaa ttcctttagc cttaatagcc tcaaagacct tacgataaaa atccacacct
    19021 tgagggttga ctttcccaca gccttgtgga aaaatccgtg accactgaat agaagtccga
    19081 aagactgtgt gaccagtctc taacaaaagc tcaatatccc gctcccaatt ttcataaaaa
    19141 gtcgatgtct tatctgaacc aatcccatta tagtaacgat ttggctccac ttggaaccag
    19201 taatcccaga gattgtctcc cttaccgtca ccagctacac gtccttctgt ctgcggtcca
    19261 gaagtagagg atccccagac aaaatccttt ggaaatctta gcataacatt tacctcttta
    19321 tctactcatt tctcccatta tacagaaaaa acaaggtaaa aactagttac attttttcct
    19381 tgtttttctt ctgattatag tttttatttc ttgcttagga tttcaagcgt ttcaagcacg
    19441 ttatctgcat gaacctcaat ggtgtcacca gttgccttga tcttaacttc tacaatgcca
    19501 tcggccgctt ttttaccaac agtgatacgg attggaagac caatcaagtc actatcgcta
    19561 aatttaacac cgacacgttc gttacggtca tctgtcaaga cttcataacc agctcccatc
    19621 aagcttgctt caagtttttc tgtcaaggct tgcgcttctt catccttgac attaacagta
    19681 atcaaatgca catcaaatgg tgccaattct ttagggaaat tgattcccca agcgtaacgg
    19741 tattcacctt ttggcgtttt gttaacaaag aggcgagcgt gttgctccat cactgctgaa
    19801 agaagacggc tgacaccgat accgtaacat cccatgatga ttggcacagc acgaccattt
    19861 tcatccaaga catctgctcc catgcttgct gaatagcgag ttccgagttt gaaaatatga
    19921 ccgatctcaa taccacgcgc aaagttaagg acaccttgtc catctgggga aatttcaccc
    19981 tcacgaactt cacggatatc cacatattct gcagtaaaat cacggcctgg gttcacacca
    20041 gtcaagtggt agccatcttc gttagcaccg acaactgcat tgcgaacatc ttgcacctta
    20101 cgatctgcaa taattttaat attctctggc aaaccaactg gtccaagtga accaaatcct
    20161 gcttgaacaa cattcgccac ttcttcttcg ctagcaacgt caaagaaatc tgctcccaag
    20221 tgatttttca acttgacttc gttgagttgg tcatttccaa ctagaagggc tgcaacaagc
    20281 tcaccatctg caatgtagaa gagggtttta atcgtttgtt cttctggaac attgaggaaa
    20341 gctgcaactt catcaattga tttaacatct ggcgttgcaa cacgagtaac ttcttcttca
    20401 gcgacaacac ggttgcttgg tttgtactcg tttgttgcca tttctaagtt agctgcatag
    20461 ctagactcac ttgagtaagc aatggtatct tcaccagaga ctatccattt gagcaattct
    20521 gccttgattt cttcttgcac ttctgcagga atttcgtcaa atgaggcaac tgacttgtcc
    20581 aagacaaccc agcggtcaag gtctgtacga gcagatgtaa tggccataaa ttcttggcta
    20641 tccttaccac ccatggctcc accgtcacca ataatagcct tgaagtctaa accactacga
    20701 gtgaaaatac gctcataagc tgctttgtac tcatcataaa cactatccaa actatcatag
    20761 ttagcgtgga aactataagc atccttcatg ataaactcac gtgtacgaag aagtccatta
    20821 cgcgggcgtt tttcatcacg atacttgggc tgaatttgat aaaggttgag tggcaattgc
    20881 ttgtaagatt taacagaatc acggacaata gctgtaaagg tttcttcgtg agttggacct
    20941 aagataaagt ctgatttttc acggtttttt agtttgtaaa ggtcttcacc ataggtttcg
    21001 taacgacctg attcacgcca caattctgca ctaagaaggg ctggagccaa catctcaaca
    21061 gcaccaatct tttcgaattc ttggcgcatg atgtttttag ctttttcaat cacacggttg
    21121 gcaagtggta gataagaata aacacctgct gaaacttggc gaacataacc agcacgcaac
    21181 ataagagcat ggctgataac ttgagcatcg cttggcattt cgcgaagcgt tgggataggc
    21241 attttacttt gtttcataat attcctcgat tatctaaaaa agagtcgcat aatgtcattc
    21301 caagtcacag caatcatcaa gacaaccatg atgaccactc cggccaaggt gacataggtt
    21361 tcaatttctt gtttcaatgg tttgcggcgg atggcttcta ggatattgag cacaatctta
    21421 ccaccatcca aggctggaat cggaataaga ttaaaaatcc caatattgat ggaaatcatt
    21481 gccaagaagt acaagatatt ttcaattcca tttttagcag catcactact tgccttaaag
    21541 atagcaacag gtccacccaa cttgttcaaa tctggttgga aaatcagatt tttcagagct
    21601 gagagaattc ggagagctga gtcagcagca gttgtaaaac cacctacaaa catggataga
    21661 aaatctgact taccccccgg ttgaacacct agaaggtaac gaccttgact atctttgggt
    21721 gtaacagtga cttgtttgtc actccccttt tcagaaatag tcacatccaa agtcggtgcc
    21781 gtcttatctt tggtttctgt ttccacagct tggatcaagc tttcccagtt gctaacctca
    21841 tgtgagccaa tcttggtaat ttgtgccgtt tctggtactc ctaccttggc caaggcacct
    21901 tggggcatga tatggaactg attggtatca acatctctga caccaccctg cataaagatt
    21961 aaaacccaaa aaacaacgac acctaagata aaattgttca taggacctgc aaaattggta
    22021 atcagtttgc cccagatagt cgcattttga tattgaacat ctaaaggtgc aatccgaacc
    22081 tcagtaccat ctgcttccac aaccgttgca tcgtgatcca ctgcaaatgt tttttcttct
    22141 tccagaacca atcctttgat aaagagcttg tcttcaaaat caaactgggt cacctgcata
    22201 gggaggactg tttgatccaa ttttttacct gagagattga tgcgtttaac cttaccatca
    22261 tcagcaagtg tcaaactaac aggcgttcct gtcttgattt cagttgtatc atcaccccaa
    22321 ccggccatgc ggacatagcc acccagaggc aagattcgaa tggtataggc cgttccatcc
    22381 ttgccaatgt gagcaaaaat tttaggtccc ataccgatgg caaattcacg tactaaaatc
    22441 cctgatttct tggcaaagta gaagtgcccg aactcgtgca ccactacaat aatcccaaaa
    22501 actagaataa aggttaaaat tccaagcata gtgtttcctc cgtcttttga ttaaaagagt
    22561 ccaaataagt gcatgattgg aaatacaagc aacatactat cgaaacgatc caaaacacca
    22621 ccatgtccag ggataaattt cccagaatcc ttaacaccaa aatgacgttt gatcgaactt
    22681 tctagtaaat caccaaattg tccagcaatg ctaaagaaaa tagcaaagac tgacatcttg
    22741 taaattccat atggaagagc aactgtactg tcaactatca taaagataat ggttactaaa
    22801 attgctccta aaataccacc caaggcaccc tcaagggttt tattaggcga tacccttggt
    22861 gctaactttc gtttcccata gttcatccca acaagatagg caccactgtc tgtcgcccag
    22921 acgatacaca aggctaagag agccttgtcc aaacctgcaa cacgagcatc tagtaaagca
    22981 ttaaatccaa agcccacgta gaagctcata gcaagaggga aaaccgcatc ctcaatcgta
    23041 taagacttgc taaaaacggt cgttcctaac atgattgaaa tcaaaacact ataggcaacc
    23101 acattcccat caactggcaa aaaagtcagg taattctcca agggaatggt caatgcaaag
    23161 gttgcaaaga gggtcaagag gccctccatc gtcatggtct ctagacctct catcttcaaa
    23221 agttcatgca tggctagcat ggctatgatt ccgattgcta tctgaagcaa gaggccccca
    23281 atcattaaaa ttggtaggaa aatagccagg gcaatccctg caaacaaggt tcttttctgt
    23341 aaatcctggg tcatatttcc tcctaaactc ctccaaatcg gcgatgacga cgattatagg
    23401 caagaatagc ttcctgcaag gccgcttcgt caaaatcagg ccataaggtg tccgtaaaat
    23461 aaagctcact ataggctccc tgccatggaa ggaaattgct caaacgtaat tctccactag
    23521 tacggataat caagtctggg tctcgtaagt ccttaggcaa atgctgagta aagagatagt
    23581 taccaatcaa ttcctctgtg atgtcacctg ggttgatttt ggcatctaaa acatcctggg
    23641 aaatcaactt aagcgcctgt gtaatctcag cacgtccacc atagttaaga gcaaaattaa
    23701 gaatcaatcc tgtgttgttc ttagtcaatt cctcagcctt ggttaaagct tcaaaggttt
    23761 gcttaggcag gcggtctgtc tccccaatca tttgaatctt aacattattc gcatgtagtt
    23821 ccgggacata attatcataa aactctactg gcaagttcat gataaacttg acttcctgat
    23881 ctggacgggt ccagttttcc gtagaaaaag catagaccgt aataaccttg acgcccagtt
    23941 tgttggctgc cttggtcacg gtttgcaatg cttccatgcc cgccttatgt ccaaaaactc
    24001 gcggttgcat acgtttttta gcccaacggc cattgccatc catgatgatg ccgatatgag
    24061 caggaacctg tgtcggaacc tctacttcca cagccttatc tttcttaaaa aatccaaaca
    24121 tgatcttatt cctattcaaa aatctatcgt ttcattatac catatttccc cattttcttc
    24181 tatcactaag ctatttattc tcaggcacca tgcccatttt tcaaaaaaat aagccgcctg
    24241 attgggcgac tttattttta tagggagatt attatgaaaa agttttagga gtttaagtta
    24301 aggtcttctt aacttatgaa cttagtgtac actccctagc ttaaagtttc cttaagtatt
    24361 tttaaaaatc aaatttttcc atttctcctg ccaatttttc ttggataaac gtgtttgata
    24421 gagttccatt cggtcttcat tttctaagaa atgaggagtt ggacgaactt gaaaattcaa
    24481 aatatcctcc aaaccataag gtgcatagag ttcaaaatct gattcttcat tcaagcgcag
    24541 tccaactgcc gtacaccgtt ctggatactt actcatagca tcacgagaac tggtatagga
    24601 agcagtgtga ggactgtgct ggtgcatata gacctgattt ttcaattccc actggtactg
    24661 aggaaaatcc tctctcagct ttttctccag taataaggtt tcctcataag aaaaatctgg
    24721 atcaaagaaa atcacatcta tatctgtttc atgatcaaaa ggggatttgt ctgacaaaag
    24781 attccagatg aaatttctga cagaacctgc tgccaactac gagtctttca aaccaaggtc
    24841 tcggatgatc gtcagaatgg ccatcatatc tggattttct ctaaaagcct ctaagatttc
    24901 ttgcttattt ttcactgtat tcataaccta agtgctcata tgccttagca gtcgccaccc
    24961 gtccagaccg tgtccgcatg ataaaacctt tttgaatcaa gtaaggctca tacatgtctt
    25021 caactgtctc acgctcttcg gcgatattga cagaaagagt tcctagacca acaggtcctc
    25081 cactgtacat ctcaatcatg gtacgaagga ttttttgatc cacatagtcc aaaccttcat
    25141 ggtcaacatc cagcatagtc aaagccttat cggtaataat atcatcgatt accccattcc
    25201 ccattatctg ggcaaaatcg cgcacgcgct tgaggagacg attggcaata cgaggggttc
    25261 cacgactacg tagggccaac tcagatgctg cctcatgagt gatttccatc tcaaaaatat
    25321 ctgccgtccg ctcgacaatt tctgtcaagt cagcatgggc ataatactcc atatgacctg
    25381 taatcccaaa acgtgcccgt agtggatttg agagcatacc agcccgagtc gtcgcaccaa
    25441 tcaaggtaaa aggaggcaac tccaaatgaa cactgcgact gccttcacca gccccaatca
    25501 taatatcgat gtagaagtcc tccatggcac tataaagcac ttcttccact gacatgggta
    25561 agcgatgaat ctcgtcaata aagaggacat ctccaggctc taactcattc aaaatcgcta
    25621 ccaaatcacc cgctttttcg ataacaggac cagacgtttg cttgagattg actcccagtt
    25681 cattggcaat gacaaaagcc atggttgttt tcccaagccc tggagggcca aataagagca
    25741 catgatccag cgcttcatcc cgcattttag cggcttcgat aaagatctga agctgatcct
    25801 taaccttatc ctgaccaata tattcacgta aatactgagg acggagcgtg cgttctacta
    25861 actcctcatc acccatcatc tcattatcta aaattctact catggctcta ttatatcaaa
    25921 aaaacaagcc acaaacaaaa aagccacctg attgggtgac tcctaagttt agcacttatg
    25981 tggtataata ttatacggca cttctacacc gcctacgaaa ggaggtgaga tagcccatga
    26041 tggaattagt actcaaaact atcatcggac caattgtggt cggtgtcgtt cttcgtatag
    26101 tcgataaatg gctaaacaag gacaaatagt gtcaaaaaag acctcaagct tatttggtcg
    26161 tgagcttggg gtcttttcta gcctatgata tagaactagt actcaattcc tttttattat
    26221 cccatagttc acgaattttg tcaaaggttt acattttctt caaccgctgt acgacaagac
    26281 ggttaagatt aagagaacgt tagggattct atcaatttca tagaaatttt gatttcgtaa
    26341 acgaagagac aatcttacat gtcacttctc atttaatacg ccactactag acaagcaaaa
    26401 tcattattac agtagttcca gttcttcaat taacagtcac ttacaatcaa attgagtttg
    26461 aactagctga agcgaccaca gacctatttc ttagttatat tcgctaaaaa agtccccgcc
    26521 aattccccga ccaaaatccg aaaaataccg aaaaatatcg aaaaattatt tttagaatag
    26581 tccccaaaag cctgaaatag agctaaaaaa ctccacctga ttgggtggag ttaagggaga
    26641 ttattatgaa aaagaaaagt ttaggatttt attaaataaa gttaggaggt ctttatttaa
    26701 taactacatg atacaagacg aaacttaaaa ctagcttaac ttttctaaaa ttttactatt
    26761 ttgcaaaaaa tttctatcac cagcacctca ccacgcaaaa aagccacctg attgggtggc
    26821 ttcattagga gattgtgatg aaaaaagttt aggattttat taaataaagt taggaggtct
    26881 ttatttaatg attatataat actagaccat ccttaaattt tgcttaagaa aaaacaagtt
    26941 ttgttatttt ttacgattca tccaagtcat ccctatccaa ttataggtgg ataagatttc
    27001 aaagcccata gaacgattaa atcccacgtt tttttctgtc tgttctgtcg ccagctggac
    27061 ttgataggcc tctttaaaat ttcctaaagc ctgtttcatc aaggagctac caatcccttg
    27121 gcgctgatag ctagacaaaa caatcaaatc ctgtacaaaa actgatgaaa aaccatctcc
    27181 aaccaaacga atcaagccca caacagcatc accatcaagt gccagataaa ttattaatga
    27241 atgatacaag gtctactcca gcatctgagg ttgatttgta taatttgtcc aaccgacagc
    27301 ctgatagaga tgcaaaacat cctcgaactt gacgatttct tgctttctaa tagtgatcat
    27361 gtcaacacct cttaaaactc tctcaagctc ttgtactgct gtccattttt atcaaaattt
    27421 tcaggacgca accatgtttc caaacgatct ttgactttgg gccagtcctt atcaatcata
    27481 gacaaccaat ccatatctct cgtacgcccc ttataaacca ctgcctgacg gaaggttcct
    27541 tcataaataa agcccaaacg ctccgcagca cgtctggatg gcaggttaag agcatcgcat
    27601 ttccactcat aacgacgata gttaagctct tcaaagacat agcgagccag tagatactgg
    27661 gcttctgtcc ctatccgtgt ccccctgagt tttggagaaa aagtgacagc tcccacttct
    27721 attactccgt tactggtcaa tacgcatgag agaaaaagtt cccaaagcct taccagttgc
    27781 cttgtctatg attgcatagt aaaaacggtc cttacgacca acatctgatt taaaaggctg
    27841 accagttcct caatgtctgc tactggctcc tgaaagaggt aggtccacat ctcctgagga
    27901 gtatcaggac cataaacagc tagcaaatcc tccgcatgct tttccactga aagagcctct
    27961 atcctagcat aacgcccttc taagagatca ataaaagtca gttcacctgg tgtataacct
    28021 tccattgact caccaatcat ctgaccatat tcgtttactg gtataacttt ctccttgttt
    28081 cgcttttcaa actttatagt tgcccatagt atagcgtatt gaaataagat gagaacaaat
    28141 cgattgggaa agtaaaatta atttctataa atgttttagc aattgtttcg tactatttta
    28201 gattcagtct actatatatc atactttcat aagaaggttc aaaaaatcct ccagattcta
    28261 ctctgaagga ttcctatctt atttcacaac aatgttaact aatttagttg gcttcaatag
    28321 tccagtggac tattgaaggt ggcagataga gctaataaac tcgttattta acgacgatat
    28381 taacgagttt attcggtacc gcaattactt tcacgatttc cttaccgtca atttctgctt
    28441 tgactttttc atcagctaaa gcgatttctt gtaattcttc acgtgatata tctttagcaa
    28501 ccatgagttt ggcacggact tttcctttga tttggacaac aatttcaatt tcatcttcaa
    28561 ccaatttgct ttcgtcccaa gttggccaag ctacataaga gattgactca cctgtttctg
    28621 cgactgtttg ccagagttct tctgccaagt gaggtgcaaa tggtgcaatc aattgaataa
    28681 agcctttggc atagtcaaca taaagcttat cttccttgtt agcagcattg acaaagacca
    28741 taagttgggc aatagctgtg ttgaatttga gagactcaat ttgctcagta acagctttga
    28801 ctgtttcgtt gtaaaccttg tcaagagcac cattgttttc cgcaaggatt tctttacttg
    28861 taatcaaacg gtaaactcgg tcaaggaact tacggcttcc ttccaaacct tcttctgacc
    28921 aagcaatcga agcatcgagt ggtcccataa acatttcata aacacgaagg gtatcggcac
    28981 cgtattgttc caccacatcg tctgggttaa caacgttctt gagcgattta gacatcttgg
    29041 ctggcgcttg ctccaactct tcccctgttt ctacatgaaa gaaggaacca tcacgttttt
    29101 caaccttgtc ggttgccaca agagcaccac ggtggtcacg gtagcttgtt cccaaaatca
    29161 tcccttggtt aaagagtttt tggaatggtt ccttagtcgg aacaacaccg aggtcataga
    29221 ggaatttatg ccagaaacga gcataaagca agtgaagtac agcatgttcc gcaccaccca
    29281 cgtagatatc tactggcaac cattgtttga ggaggtcctc atcagccaat ttctcagtat
    29341 tgtgcgggtc aatatagcgg aggtagtacc agcttgaacc agcccattgt ggcatggtgt
    29401 tagtttcacg acgacctttg acaccatctt cacgagtcac ttcaagccaa tctgtcaagt
    29461 tagctagtgg actttcacca gtacctgaag gacggatatc cttggttaca ggcaagacaa
    29521 gcggcaattc agtttcagga acagctgttg aagttccatc ttcccaatga atgattggaa
    29581 ttggctcacc ccagtaacgt tgacggctaa agagccagtc gcggaggcgg taggtaacct
    29641 tctcctgacc acagcctttt tcttccaagc aagccacaat cttggcaata gcgtcttctt
    29701 tattcaatcc atctaggaag tctgaattga catgcaggcc atcctctgtg taggcagctt
    29761 cttcgacatt tccaccttca agtacttcga cgattggaag gtcaaattgt ttggcaaatt
    29821 cccagtcacg ttggtcgtgg gcaggcacag ccataaccgc acctgttcca taactagcaa
    29881 gaacatagtc cgcaatccag attggcattt ccttaccatt gacagggttg atggcatagg
    29941 cacctgtcca aacaccagtt ttttccttag caaggtctgt acgaaccaag tcagacttaa
    30001 ggctggcttg gtgtttatag tctgctacag cttctgcttg ctctgaactt gtgatagcgt
    30061 ctactaattc atgttcagga gccaagacag tgaaagtcgc accgaaaagt gtgtccggac
    30121 gagtagtaaa gactgtaaat tccttgtctg ttccttttac tttgaaagtt acattggcac
    30181 cagttgattt accaatccag ttgcgttgca tatccttgat agactctgac caatctagtt
    30241 catctaagtc attgagcaag cgctctgcgt aagccgtgat tttgagcatc cattggcgca
    30301 ttggtttgcg gacaactgga tagcctccac gctcagaagt tccgtcagga agcacttctt
    30361 cattggcaat ggcagttccc aattcctcaa cccagtttac tggcacttca gcttcatagg
    30421 ccaagccttt ttcgtaaagc ttggtgaaaa tccattgagt ccacttgtag tagtttggat
    30481 ctgttgtgtt gacttcacga tcccagtcat aagaaaatcc aagcgcattg atttgacgtt
    30541 tgaagttggc aatgttttcc gctgtaaatt ctgctgggtc attaccagta tccatagcgt
    30601 attgctctgc aggcaaacca aaagcatccc aacccattgg gtgaaggaca ttgtagcctt
    30661 gcgcacgttt gtaacgactg aggatatcgg ttgcagtata accttctggg tgtcctacgt
    30721 gcagaccaac tccagacgga taagggaaca tatcaagcgc ataaaactta ggttttgatg
    30781 tatctgttcc tgtcttaaat gtatgatgtt ctgcccagta gccctgccac ttaggctcaa
    30841 tttctttatg attataaaaa ctcatggtct ctctccaatt ttgtgatgtt actattatac
    30901 catttttgag ggaatttgaa atgtgtttaa agaaaaaact gtatactgta tctcattaat
    30961 tttgatgact atgaattgct ctatctccca ctttttatcc cattgttatg cagtaaatca
    31021 aggagtaagt caagacgctt atctcgtata gcacaaaata cttattttag accgaagata
    31081 aaactggaat g
//
LOCUS       DAVHKZ010000026        31086 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000026 DAVHKZ010000000
VERSION     DAVHKZ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31086
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.026"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..1138)
                     /locus_tag="VVO74_001408"
     CDS             complement(<1..1138)
                     /locus_tag="VVO74_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU5695421.1"
                     /translation="MLSLDQIHLLLNTPEDEFHDFKQKWHHSKTELVRDILNFVNTSH
                     HEDCYIIFGIDNITLDIIGVNNDDNRRNEEDLTDLLHKLFISTNNQIKISIQTETIDN
                     KEIDILIIHDTDKVPVFLTKDYKPKKDTALPKGLIYAINGSINTPKDSSAPFELINEL
                     FQKFNHTDLNIKEQYFHVLKDYKNWFFIENEDGRFFIYNPNPDFYIKLNDDDANRFKT
                     MSYSLNQYQTNIDWQLVQLRYRHLTIDECMAMYLDQGNCLVPSPEVESFKIDYQETIY
                     YHCLYKNTLKYQLLKVFSSIPGLEKYPLTRFKNSIVIYDTKLELKKTHNLINSKFSSK
                     DIVNQLEVTEKDFDFYYKKARHKNPDYSIQENQVNLTELNLVRLL"
     gene            1500..1856
                     /locus_tag="VVO74_001409"
     CDS             1500..1856
                     /locus_tag="VVO74_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695422.1"
                     /translation="MKRDVRDIRKQFRLTEAEEKQILALMRERGETNFSDFLRKSLLS
                     SDLQKQMETWFALWQSQKLEQISRDVHEVLILAQSERQVTQEHVSILLTCVQELIQEV
                     ANTIPLSKEFREKYMR"
     gene            1861..2226
                     /locus_tag="VVO74_001410"
     CDS             1861..2226
                     /locus_tag="VVO74_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEU5695423.1"
                     /translation="MEHRYRTNLKKVFLSDSELNQLNINIDQSGCKSFSEYARRTLLD
                     PGMNFITIDTNGYQDLVFELKRIGNNINQIARSVNQSQLIPGEELQELKKGIGELIKE
                     VDKEFNLQAQKLKEFHGHH"
     gene            2213..4036
                     /locus_tag="VVO74_001411"
     CDS             2213..4036
                     /locus_tag="VVO74_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEU5695424.1"
                     /translation="MVITKHFAIHGKSYRRKLIKYILNPEKTNNLALVSDYGMKNFLD
                     FPSYEEMVQMYHENFISNDTLYDFRHDRMEENQRKIHAHHIIQSFSPEDHLTPEQINR
                     IGYETVKELTGGKFRFIVATHVDKDHLHNHIIINSVDSNSDKKLKWDYKVERNLRMIS
                     DRFSKIAGAKIIENRYSHQRYEVYRKTNHKYELKQRLYFLMEHSRDFEDFKKNAPLLH
                     VEMDFRHKHATFFITDSTMKQVVRGKQLNRKQPYTEEFFKNYFAKREIESLMEFLLLK
                     VENMDDLLQKAKLFGLTINPKQKHVSFQFAGVEVKETELDQKNLYDVEFFQDYFKNRK
                     DWQAPETEDFVQLYQEEKLSKEKELPSDEKFWESYQEFKSNRDAVHEFEVELSLNQIE
                     KVVDDGIYVKVKFGIRQEGLIFVPNMQLDMEEDKVKVFIRETSSYYVYHKDAAEKNCY
                     MKGRTLIRQFSYENQTIPLRRKATVDMIKEKIAEVDALIELEVENQSYVTIKDELVHE
                     LAASELRINELQERMSTLNQVAEYLLASVESKQEMKLNLSKLNITENISANIVEKKLK
                     SLGNQLELERGRYEKMVVRLDKFINRLNTGLSKGDGIDFQK"
     gene            4150..5016
                     /locus_tag="VVO74_001412"
     CDS             4150..5016
                     /locus_tag="VVO74_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5695425.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEEVNELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKFYMEWIKSLIDFYFYGQKEEAITRLENMLPQLNVSDLNYLQVSNTLFN
                     FYYDIEDLERFNEIRDKLEHQVNQLNLNTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKEYRTTYLLADLYLLMGSVSENFSSKSSVKEYFETAHFLYKLEENMSMA
                     LKVEHYFADITE"
     gene            5607..5858
                     /locus_tag="VVO74_001413"
     CDS             5607..5858
                     /locus_tag="VVO74_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000098314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695426.1"
                     /translation="MSSQMKAFLNELQGNMEVVGEFFDNPEKVIRKFGIVGREKEALL
                     IRDLNDMDDYALSIQNSVASPSGAHSSTCHFVRQDLQSA"
     gene            6087..6389
                     /locus_tag="VVO74_001414"
     CDS             6087..6389
                     /locus_tag="VVO74_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695427.1"
                     /translation="MKNKYDVKRIIPDELSESLDIFLKNYSETGLSDYNTYLFYGFIL
                     KSYKLPRENRYSIKLLVKELQNRGLKVTLIINIYYHALNCLALNDGLKIYEEDFLI"
     gene            6386..7725
                     /locus_tag="VVO74_001415"
                     /pseudo
     CDS             6386..7725
                     /locus_tag="VVO74_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105427.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
     gene            7739..8656
                     /locus_tag="VVO74_001416"
     CDS             7739..8656
                     /locus_tag="VVO74_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695428.1"
                     /translation="MNCFLKMNNVSVRYDDVIALKDITLQINKGDFIGLLGSNGAGKS
                     TLINSIVGFQEIYLGEIEYCDKDLIVSSQPFAHLGFTPQTTVIDFYTTVKDNVILGLN
                     LAGKFGKNAEKLCQIALEIVGLADKKNNLVETLSGGQLQRVQIARAIAHNPDFYILDE
                     PTVGLDTESAEKFLMYLKDKSLEGKTIIISSHDINLLEKFCKKILFLQNGSISFFGDM
                     RDFVDNSTIKLNFSMQNRISRYQIEFLENFRFKVHIEDNDSFTIEVPIEENILDVINE
                     VGKACEIKNFSTSKLTLQESYLQRIGGEK"
     gene            8653..9453
                     /locus_tag="VVO74_001417"
     CDS             8653..9453
                     /locus_tag="VVO74_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5695429.1"
                     /translation="MKADQLRHKSDLGLRGLAIIAKNEIIAFFRSKGLIISQFLQPIL
                     YVVFIIIGLNSSIKNIQFNDIKTSYAEYTIIGVIALLIIGQMTQVIYRVTIDKKYGLL
                     ALKLCSGVRPLYYILGMSIYSILGLIVQEIIIYIITLAFEINIAMDRFFYTVLLSIVV
                     LLFWDSLAILLTMFINDYRRRDIVIRFVLTPLGFTAPVFYLIDSAPSIVRWIGQLNPL
                     TYQLTILRNFYFKNSTTLELVFLLLTSLLVLISVSFIIPKIKLILIER"
     gene            9611..10084
                     /gene="tnpA"
                     /locus_tag="VVO74_001418"
     CDS             9611..10084
                     /gene="tnpA"
                     /locus_tag="VVO74_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSpn6 family
                     transposase"
                     /protein_id="HEU5695430.1"
                     /translation="MREDNQSLSHTTWNCKYHIVFAPKYRRQIIYGRYKASIGRIIRD
                     LCERKGVIIHEANACSDHIHMLISIPPKLSVSSFMGYLKGKSSLMIFDKHANLKYKYG
                     NRKFWCRGYYVDTVGRNQKVIAEYIQNQLQEDRVADQLTLFESVDPFTGEINKRK"
     gene            10341..10562
                     /locus_tag="VVO74_001419"
     CDS             10341..10562
                     /locus_tag="VVO74_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5695431.1"
                     /translation="MYRRLRDLREDHDLTQKQIATILSFTNSAYAKIERSEHALTADV
                     LVKLSDFYDVSTDYLLGLTDFPDKIRFRK"
     gene            10864..11097
                     /locus_tag="VVO74_001420"
     CDS             10864..11097
                     /locus_tag="VVO74_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU5695432.1"
                     /translation="MEIKYVSVENSVAEWADKKSILKRWEGLNLYTLNRWIKEMRENK
                     RFSLYVINPTHKLVFINLEGFECFLRWKQKRTK"
     gene            11173..12681
                     /locus_tag="VVO74_001421"
     CDS             11173..12681
                     /locus_tag="VVO74_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU5695433.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKYKDPLTDKWRTVTVSYTRNTSRAR
                     KQAEREVMDKIEKLTSSLESQYNPEMITTFGELKESWFQTWCVSVKPQTIKREELVIE
                     RLGKIIGDEFLLDRITPLLMKNCLNKYLDKYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KYSPMTAVKIDVPLEKKRESRKRLDAKFLAIHELQAFFDVLGQCRNASYYDLAIVLLL
                     TGIRIGEAAFLPSDVDFDKGILHIDKALQYHDLKVDEFYFDTTKTVNADREVALPIAA
                     SEAIQRTIKRNQEFEAYMEQNPSPAFKKCDSVFQTEYGSPITSHSFRQVLKRVEEKLL
                     KNCQKDYGFKWVKHVTPHSFKHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHN
                     ISRSQENTVTALNQFVEKHNFHFKELKSYTCKYSRMIEQFIETCDDNNKVELSVDEFK
                     DLLHLGSRYSPKHIVSNLLLKIKKDIVKYHPQFDIKIVKLSGNQIKGFSISW"
     gene            12762..13613
                     /gene="ylqF"
                     /locus_tag="VVO74_001422"
     CDS             12762..13613
                     /gene="ylqF"
                     /locus_tag="VVO74_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU5695434.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEKAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            13600..14379
                     /locus_tag="VVO74_001423"
     CDS             13600..14379
                     /locus_tag="VVO74_001423"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU5695435.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQVVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            14395..15945
                     /locus_tag="VVO74_001424"
     CDS             14395..15945
                     /locus_tag="VVO74_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEU5695436.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            16531..17601
                     /gene="xerS"
                     /locus_tag="VVO74_001425"
     CDS             16531..17601
                     /gene="xerS"
                     /locus_tag="VVO74_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU5695437.1"
                     /translation="MKREILLERINKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAINLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(17674..18663)
                     /locus_tag="VVO74_001426"
     CDS             complement(17674..18663)
                     /locus_tag="VVO74_001426"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU5695438.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(18727..20412)
                     /gene="lpdA"
                     /locus_tag="VVO74_001427"
     CDS             complement(18727..20412)
                     /gene="lpdA"
                     /locus_tag="VVO74_001427"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU5695439.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELES
                     EEDGYLIAILKGEGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESSLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVITDKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            complement(20476..21519)
                     /locus_tag="VVO74_001428"
     CDS             complement(20476..21519)
                     /locus_tag="VVO74_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU5695440.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     RVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            complement(21737..22729)
                     /locus_tag="VVO74_001429"
     CDS             complement(21737..22729)
                     /locus_tag="VVO74_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEU5695441.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            complement(22745..23713)
                     /locus_tag="VVO74_001430"
     CDS             complement(22745..23713)
                     /locus_tag="VVO74_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU5695442.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            complement(23867..25228)
                     /gene="pdrM"
                     /locus_tag="VVO74_001431"
     CDS             complement(23867..25228)
                     /gene="pdrM"
                     /locus_tag="VVO74_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU5695443.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            complement(25239..25499)
                     /locus_tag="VVO74_001432"
     CDS             complement(25239..25499)
                     /locus_tag="VVO74_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695444.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            complement(25513..26781)
                     /locus_tag="VVO74_001433"
     CDS             complement(25513..26781)
                     /locus_tag="VVO74_001433"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU5695445.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALFLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            complement(26794..27258)
                     /locus_tag="VVO74_001434"
     CDS             complement(26794..27258)
                     /locus_tag="VVO74_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU5695446.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            complement(27268..27921)
                     /locus_tag="VVO74_001435"
     CDS             complement(27268..27921)
                     /locus_tag="VVO74_001435"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU5695447.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            complement(28059..28706)
                     /locus_tag="VVO74_001436"
     CDS             complement(28059..28706)
                     /locus_tag="VVO74_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695448.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSDDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            complement(28720..29433)
                     /locus_tag="VVO74_001437"
     CDS             complement(28720..29433)
                     /locus_tag="VVO74_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU5695449.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(29892..30272)
                     /locus_tag="VVO74_001438"
     CDS             complement(29892..30272)
                     /locus_tag="VVO74_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEU5695450.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            complement(30694..>31086)
                     /locus_tag="VVO74_001439"
     CDS             complement(30694..>31086)
                     /locus_tag="VVO74_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU5695451.1"
                     /translation="DHVQRNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKP
                     ESPKPTEEPEEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLK
                     NNLLFGTQDNNTIMAEAEKLLALLKESK"
BASE COUNT         9948 a         5650 c         5779 g         9709 t
ORIGIN      
        1 tcaataacct aactaagttt aattcagtta gatttacttg attttcttgg atgctataat
       61 caggattttt atgtctagct tttttatagt aaaaatcgaa atctttttct gtaacttcaa
      121 gttgattcac tatgtctttt gatgagaatt tactatttat caagttgtga gtctttttca
      181 attctaattt tgtgtcataa attactatac tatttttaaa tctagttaaa ggatattttt
      241 cgagaccagg tattgaagaa aatactttca gcaattggta ctttaaagta tttttgtata
      301 agcagtgata ataaatagtc tcctgataat ctattttaaa actttctact tcaggggaag
      361 ggactagaca attaccttga tctaaataca tagccataca ctcgtcaatt gtaagatgac
      421 gatatcgaag ttgtactaat tgccaatcaa tattagtctg gtattgattt aaactataag
      481 acatagtttt gaaacgattt gcatcatcgt cgttaagttt aatataaaaa tcgggattag
      541 gattataaat aaaaaatctt ccgtcttcat tttcaatgaa gaaccaattt ttatagtctt
      601 ttaaaacatg aaaatactgc tctttgatat ttaagtcggt atgattaaac ttttgaaaca
      661 actcatttat taactcaaaa ggagcagagg agtctttagg ggtatttata gagccattta
      721 tagcatatat taatcctttt ggtaatgcag tatctttctt aggcttataa tcttttgtta
      781 aaaatacagg aactttatct gtatcatgaa taattaagat gtcaatttct ttgttgtcta
      841 tagtttcagt ttgtatgcta attttaattt gattatttgt tgatataaag agtttatgta
      901 gtaaatctgt tagatcttct tcatttcttc tattatcatc attgtttaca ccgattatat
      961 ctaaagtgat attatcaatt ccaaagatga tataacaatc ttcgtgatgt gatgtattga
     1021 caaaatttaa gatatcacgc accaattcag tttttgaatg atgccatttt tgtttaaaat
     1081 catgaaactc atcttcgggt gtattcaata gtaagtgtat ttgatctaga ctcagcattt
     1141 ttatttctcc aaatattagt ttacagaaat tttatcatag aatcagagaa agtcaatcat
     1201 aactatatta gctgtgatac ctttttcaaa tcttccctgt tatcctaata tcattcatag
     1261 aaaatcaatt tttgattttc tatgggggtt tgggggcgaa gtcaccaagt tatcttatcg
     1321 ttggctgtca aaactagaaa gttttgatag gctggcgata tgatttttga gatattgtgg
     1381 acacaatatc tgagctcgca aagccttaca agaatgaaaa tcagttgttg gaaaagtgta
     1441 ctgacattgt atggtagctc acattgtcag tacaagtatt ttggaaagga agtagcagta
     1501 tgaaacgaga tgtgcgtgat attcggaaac aatttcgttt aacagaagca gaagaaaagc
     1561 aaattctagc tttgatgaga gagcggggag agactaattt ctctgatttt cttcgtaaaa
     1621 gtttactttc ctctgattta caaaaacaga tggagacatg gtttgccctc tggcaatccc
     1681 aaaaactaga acaaatcagt cgtgacgttc atgaagtttt aatcttggca cagtcagaac
     1741 gtcaagtcac ccaagagcat gtatctattc tcttaacgtg cgtgcaggaa ttgattcaag
     1801 aggttgcaaa caccataccc ctcagtaaag aatttcgtga gaagtacatg aggtaagcac
     1861 atggaacatc gttaccgaac caatctcaag aaagtgtttt tgtctgatag tgagttgaac
     1921 caactaaata taaatatcga tcaaagtggt tgtaaatcct tttctgaata tgcgagacga
     1981 actctactcg atcctggtat gaattttatc acgattgaca caaacggtta ccaagattta
     2041 gtgtttgagt taaagaggat tggcaataat atcaaccaga ttgctcgaag tgttaatcaa
     2101 tctcagttaa ttcctggtga agaattgcag gagttgaaaa aaggaattgg tgaattgata
     2161 aaagaagttg ataaggaatt taatctgcaa gcgcagaagc taaaggagtt ccatggtcat
     2221 cactaaacac tttgccattc acggaaagag ttaccgcaga aagcttatca agtacattct
     2281 caatcctgag aaaaccaata atcttgcctt ggtgtcggac tatggcatga agaattttct
     2341 ggactttcct agctatgagg aaatggtgca gatgtatcat gaaaatttca tcagcaacga
     2401 tacgctttac gattttcgcc acgacaggat ggaagaaaat caacgaaaaa tacacgctca
     2461 ccacatcatt cagtctttct cgccagagga tcatctcact cctgaacaaa tcaatcggat
     2521 aggttatgag actgtgaagg aattaactgg tggcaaattt cgttttatcg ttgcgaccca
     2581 tgttgataaa gaccacctgc acaatcacat cattatcaat tcagtagata gcaattctga
     2641 caaaaagctc aagtgggact acaaggtgga gcgaaatctt cgcatgattt ctgaccgttt
     2701 ttctaaaatc gcaggtgcta aaatcattga gaaccgctat tctcaccagc ggtatgaagt
     2761 ctatcgtaag actaatcaca agtatgaact caagcagcga ctctattttt tgatggaaca
     2821 ttctagggac tttgaggatt tcaaaaagaa tgctccgcta ctacatgtgg agatggattt
     2881 ccgtcacaag catgccacct tttttattac ggactcaact atgaaacagg tggtgcgtgg
     2941 caagcaactc aatcgcaagc agccttacac agaagaattt tttaagaact actttgccaa
     3001 aagagaaata gaaagtctca tggaattttt attgctgaaa gttgagaata tggatgattt
     3061 acttcagaaa gcaaaacttt ttggactaac tatcaatcct aaacaaaagc atgtttcttt
     3121 tcaatttgca ggagtggagg taaaggagac agagctagac cagaaaaatc tttatgatgt
     3181 agagtttttc caagattatt ttaaaaatag aaaagattgg caagctccag aaactgagga
     3241 tttcgttcaa ctttatcaag aagaaaagtt atccaaagaa aaagaacttc caagcgatga
     3301 gaagttctgg gagtcctatc aagagttcaa gagtaacaga gatgccgttc atgaatttga
     3361 ggtggagttg tcactcaatc aaattgaaaa agtagtggat gatggaattt acgtcaaggt
     3421 caagtttggt attcgtcagg agggacttat ctttgtgccg aacatgcagc ttgatatgga
     3481 agaggataag gtgaaggttt tcatcaggga aaccagctcc tactatgtct accacaaaga
     3541 cgctgccgag aaaaattgtt atatgaaagg tcgaacctta attagacagt tcagctatga
     3601 aaatcaaacc attccattac gcagaaaagc gacagtcgat atgattaaag agaagattgc
     3661 ggaagtggat gctttgattg aactggaagt agaaaatcaa tcttatgtca cgattaaaga
     3721 tgagttagtg catgaactag cagcgtctga attaagaatc aatgagttgc aagaacgaat
     3781 gtcaaccttg aatcaagtag cagaatatct actggcttca gttgaaagta agcaagaaat
     3841 gaaattaaat ctttcaaaac tgaatataac tgagaatatc agtgctaata ttgttgagaa
     3901 aaaattgaag agcctgggga atcaactgga attggaaagg ggcaggtatg aaaagatggt
     3961 agtcaggcta gataaattta taaatcgctt aaatacagga ctttcaaaag gagatgggat
     4021 agattttcaa aaataggaat ctagccaata attatataca atgtgtatct tttgtaaaat
     4081 atatttgaaa tttagattta atcatgttac aattaacatt gaaatcaaat agaaaaggaa
     4141 gatgcaaacg tgggtacact attagcaaca agattaaaaa atagacgaaa agaattaaaa
     4201 atgtctcagc gagaattagc tgagggtatc tgtaaacagg ggcaaattag tcgattagag
     4261 agtggagagt tcacccctgg agcggatttt ttacatgccc ttgctaagaa attaaaagtt
     4321 agtatggact acttttttga tgagcaggtt gtagaggaag tcaatgagtt atcagagttt
     4381 aagaagttag cacagacatt tatcacaaat cgtaattatg aatctttaaa atatatatat
     4441 gaattggaaa atgtaaaagc ccatcgctta tctctagcag ataaatttta catggaatgg
     4501 ataaagtctc ttatagattt ttatttttat ggacagaaag aagaggcaat tacacgatta
     4561 gagaatatgc tacctcagtt aaatgtatct gatttgaact accttcaagt ttcaaacact
     4621 ctattcaatt tttattatga tattgaagat ttagaacgtt ttaatgagat tagagacaag
     4681 ctagagcatc aagtgaatca gcttaattta aacacaattg aagagttaga actatcaatt
     4741 aagttcaatt ataacgtttg tcgataccta tggttacaga aaaatattga agaagctatt
     4801 acgaaaatca cagctacgat aaagcaatgt aaggagtaca ggacaactta tctattagct
     4861 gatttgtatt tattgatggg aagtgtaagt gaaaattttt cttctaaaag ttcagtaaaa
     4921 gaatattttg agactgctca ttttctctac aaacttgagg aaaacatgtc aatggctttg
     4981 aaagtcgaac attattttgc agatataaca gaataaggaa tacggtgttc tagtgagcat
     5041 cgttttttaa atctaatttg aatacaaaaa agtattaaat aaaaaaaaat aaaaaaagat
     5101 tataaaaata cttgacaagc taattttgaa gtgataaaat aaatgcaaga aaacgaaagg
     5161 agaggtatat gagaagtttg tttaggaaaa ttgttgcttt gttagtcata ggattaatcc
     5221 tattagggac tgctggagga actcaagttc ataagatggc tagagggatt gatcaaggtc
     5281 ctgcgaatgg tatttataga taggagatta tagtcactta aaaatcaaca aattataaaa
     5341 tttttgtttt acttaaatag atattttatg atgggcgaag tttttataac tagttcctat
     5401 aagtacagaa acctatttta atttactaat ttcaaaacaa ttttttgaga tatatgtaat
     5461 taaatctaaa ttaagcttta aaaaattatt tttagcaatt tgattttgaa agtgtcatgc
     5521 agcaatatga aagcgtagaa tagaggtgtt tccaatgtac aagtaagttt tgattccaaa
     5581 taaagtaata gaaaaggagc tatataatga gtagtcaaat gaaagctttc ttgaatgaac
     5641 ttcaaggaaa tatggaagtt gttggagaat tttttgataa tcctgaaaag gtaattagaa
     5701 aatttggaat tgtcggaaga gagaaggaag cattgctaat ccgtgactta aatgatatgg
     5761 atgattatgc tctttcaatt caaaatagcg ttgcatcgcc ttctggggca catagtagca
     5821 cttgccattt tgttagacaa gatttacaat ccgcataatt gttaatatat aaaacataaa
     5881 atttcaattt tcaattaggg ataatagaat tccttactat gatatagaaa gtgaattaat
     5941 taggaaatct tagtcagagg tttctgatta attcattttt tatatattaa gagtgatgtg
     6001 aaatgttcaa attgtgagac tactctcgga ttgttgtata gaaatttaaa attttattgt
     6061 gagcttttta aggaagagtg gccgatatga aaaataaata cgatgttaaa agaattattc
     6121 cggatgaatt atcagaatca ctagatattt ttctaaaaaa ttattctgaa actggattgt
     6181 cagattataa tacttatctc ttttatggtt ttatcttgaa gtcctataaa ttgcctcgag
     6241 aaaatagata tagcataaaa ttattggtga aggaattaca aaatagagga ctgaaagtta
     6301 cattgattat caacatttat tatcacgctt taaattgttt ggctttaaat gatggtctaa
     6361 aaatttatga agaagatttc ttaatatgaa ttacgaaaag tatttaaact atttggacta
     6421 tgaaactgaa atagaagacg cataccataa tttattatta gaatataaaa ttagtgataa
     6481 ttttagtgat gaacattggt tatataattt gccgtctaat atcacccaat ctaagggatt
     6541 taaaatacac ctgagcgctt caatattaaa tgctaatttg gttgctaaaa aattctttga
     6601 ttttatattt tctagagaga agaagataaa tttcaaaatt ttggttagca ttaaagaact
     6661 ttctttgcaa aatacagggc ttaatggtta ttcacaagtc gggaaattca ttacaattta
     6721 tccaaaagat aataaagagt ttcaacgttt gttacacaaa ttagaaatat tgtataaagg
     6781 tgtaaagggt gtaaacatac catcagattt caacttagcg aggttgtata ttacagatat
     6841 ggggagttcg taaaagatag cactttcaag gataaaagag ataagaaaat cccttcaaat
     6901 gtgaatgttc caataaggga ttactatatt ccaagatata acactattcc tgatcaatat
     6961 attattttgg aagtgatttc taaaaatgcc aaaggtggag tttataaagt atttaatact
     7021 caaaagcgag tttattcttt attaaaagaa gctagtgatt tatcgttggt tgattttaca
     7081 aatagagatt ctgtgaatcg tttaataaat gaaagagaaa tattagtaga attggaaaag
     7141 gaggaattta ctccaaaagt ttttaacgat ttttacataa agaattcgta ttttgtggaa
     7201 tttgagttta ttattgcaga taaattaagc gagtataata tggttagtgg ctcgtatgat
     7261 tggtttttaa cattaattga ttatatggag ataataaact ccaaatataa tctttcctat
     7321 agagatttat catttaataa tatacttatt gataatagaa ataatattta tattatagac
     7381 tttgagcatg ccctaaggaa agaaactcaa attgaagaaa aaaagttgcc tctatttgga
     7441 actccagggt tttatgaaac caacttaaat ttattgaata atcaaccaga ggatattatg
     7501 ggattggttt tgttattata ttggagtcag aatttagatg attttaacgt cttttcaaaa
     7561 atgagttttt tagaagcgat ggagtatgca atgaatttta attcgcgtcg cttagacaca
     7621 cttgataaat cagattggct ttatgatatt tataaaaaag cgttcaatta taaatatgat
     7681 actttttctg aattaaaaaa agattttata gaggtattaa aataaaggta ggggtgttat
     7741 gaattgtttc ttgaaaatga ataatgtaag tgttcgttat gatgacgtaa tagctttaaa
     7801 agatataact ttacaaataa ataagggaga tttcattggc ttattaggtt caaatggtgc
     7861 aggtaaatct acgttaatta attctattgt aggttttcaa gagatttatt taggagaaat
     7921 agagtattgt gataaagatt tgatagttag ttctcaacct tttgctcatt taggctttac
     7981 tcctcaaacc acagtaattg atttttatac tactgtgaag gacaatgtaa tattggggct
     8041 gaaccttgct ggaaagtttg ggaaaaatgc tgagaagttg tgtcaaatag ccttagaaat
     8101 tgttgggtta gctgataaaa aaaataattt ggtagaaaca ttgtcaggtg gacaactgca
     8161 acgcgtccag attgctagag caatagctca taatccagat ttttatattt tagatgaacc
     8221 taccgttggt ttagatactg aatctgccga aaaattttta atgtatttaa aagataagag
     8281 tttggaagga aaaactatta tcatatcttc acatgacata aatctactcg aaaagttttg
     8341 taaaaaaata ctttttttac aaaatggctc catatcattt tttggtgata tgcgtgactt
     8401 tgtagataat tcaactatca aattaaattt ttcaatgcag aatagaattt ctagatatca
     8461 aattgaattt ttagaaaatt ttagatttaa agttcacatc gaagataatg atagttttac
     8521 aatagaagtc cctatagaag aaaatatctt agatgttatc aatgaggtag gaaaagcatg
     8581 tgaaattaaa aacttttcaa caagtaaatt aaccttacaa gaaagttatt tgcaaagaat
     8641 aggaggagaa aaatgaaggc tgatcaatta aggcacaaat cggacttagg tttaagaggt
     8701 ctagcgatta ttgctaaaaa tgagattatt gcttttttta gaagtaaagg tttaattatt
     8761 tctcagtttc tacaaccaat cttatatgtt gtttttataa taataggatt aaattcttcg
     8821 ataaagaaca ttcagtttaa tgatataaaa acctcttatg cagaatatac aatcattggt
     8881 gttatagctt tattgataat cgggcagatg actcaagtta tttatagggt gacaatagat
     8941 aaaaaatatg ggctacttgc tcttaagtta tgcagtggag ttcgtccttt atattatatt
     9001 ttagggatga gtatctattc tatattaggg ttgatagttc aagaaattat tatatatata
     9061 attacgttag cgtttgagat aaatatcgca atggatagat ttttttatac agttttgtta
     9121 tctattgttg ttttattatt ttgggactcc cttgcaattt tacttacaat gtttatcaat
     9181 gattacagaa gacgtgatat tgtaatacgt tttgtactaa caccgcttgg ttttacagct
     9241 cctgttttct acttaataga ttctgctcct agtattgtga gatggattgg tcagttaaat
     9301 cccttaactt atcaattaac tattttgaga aacttttatt ttaaaaattc aacaactttg
     9361 gaattagttt tcttattgtt aacatcatta cttgtcctta tatctgtatc ttttattata
     9421 ccaaagataa aattgatact gatagaaaga taaaagttgg gtcatccaac ttttttgttg
     9481 tctcccgaaa accactagct atgctagtgg ttccatagag cttttagcgt ggtaacaaaa
     9541 agaacctcct aaaatgataa gatagaagtg gtttctccgc cactacaaca tatcatacag
     9601 gaggtacctc atgagagagg ataatcaaag tttatcacat accacatgga attgtaaata
     9661 tcatattgtt tttgcaccca aatatcgtcg tcaaatcatt tatggcagat acaaagctag
     9721 tatcggaaga atcatacgtg acttatgtga gcgtaagggt gtaataatcc atgaagcgaa
     9781 tgcttgttca gaccatattc acatgcttat cagtattcct ccgaaactta gtgtttcgtc
     9841 ctttatgggc tatttaaagg gcaagagcag tttgatgatt tttgataagc atgcgaattt
     9901 aaaatacaaa tatggcaatc gcaagttttg gtgtagaggc tattatgtag atacggtagg
     9961 ccgtaatcag aaagtgatag ctgaatatat tcagaatcaa ttacaagaag acagagtagc
    10021 agaccagctc acgttattcg agtcagtaga tccgtttact ggcgaaataa ataagaggaa
    10081 gtaactaagg tgctttagca cctgctcggg aaagtggtgc gcgaggaagc tatttcggtg
    10141 ggcctttggc cctggccggt agaagcggct tatagccgca gaacaaacca ccagttcaca
    10201 ctggtggttt tgatttaaaa aacttgatac ataaaaataa aagtctatat aaaggatggt
    10261 aaaattcctg ttgtccgatt tggacaatat cctaaatagt tacaatatat ggtctatact
    10321 ttttcttagg agaaagctag atgtacagac gtttgagaga tttgagggag gatcatgatc
    10381 tgacccaaaa gcaaatagct acaatacttt cgtttacaaa ttcagcttat gccaaaattg
    10441 aacggagtga gcatgcgttg acggctgatg tattggttaa actctcagat ttctatgacg
    10501 tcagtacaga ctatttattg ggattaactg attttcctga taaaattcgc tttagaaaat
    10561 aatctcctca atttcataga gtttgaaaat gagtgagatt ttttatttgc cctttgacaa
    10621 ctgaatagcc taaaatggta ctttcctcat ttgtggagca gttttgcttg attcgccaag
    10681 ataggagcgg ggacaatcac caataaaata gagcgatact ctatctgcca tgatgcaaat
    10741 gatatacaat gatacttctg aacgttcagg ctgccgtcgt aaaagagcag taagtgagat
    10801 tcttatgatg accccatcag tcatgccatg gagggagaag aaattattcg aaaggatgat
    10861 aatatggaga taaaatacgt atctgttgaa aattcggtag ctgagtgggc ggataagaaa
    10921 agcatactga aacgatggga aggtttgaat ctctacactc ttaacagatg gatcaaagaa
    10981 atgagagaaa ataagagatt ttctttatac gtcatcaatc ctacacataa gctggtgttt
    11041 ataaatcttg agggattcga atgctttttg agatggaaac aaaagcggac aaaataagga
    11101 agtcatggta taatatagag tagttattta ttctatacaa caatgattta tttcttttcg
    11161 aggaattaaa ttatgtatta tgtaactaaa acaaattcaa aaggacaacc cttgtatcaa
    11221 gtggttgaaa aatataaaga tccacttact gataagtgga gaacagtaac tgtcagctat
    11281 actagaaata ctagtagagc acgaaagcaa gctgaaagag aggtaatgga taaaatagaa
    11341 aaactgacct cttcccttga aagtcagtac aatcctgaaa tgattacaac ttttggagag
    11401 ttaaaagaga gttggtttca aacttggtgc gtatctgtca agccccagac aataaaaagg
    11461 gaagagttgg tgatagaacg gcttggtaaa attatcggtg atgaattttt actcgatcga
    11521 attacaccac tactgatgaa aaattgtctt aataaatatc tggataaata cgacgcttca
    11581 ccttcaacaa tgacacatat aaaaagtacg tgtaacaaga tatttaatca cggtgtgcta
    11641 tacaatgtca ttaagtactc tccaatgacc gctgttaaaa tagatgtgcc tctggagaaa
    11701 aagagagaat caagaaaaag gcttgatgct aaatttcttg caattcatga attgcaagcc
    11761 ttttttgatg ttttagggca gtgtagaaat gctagctatt atgaccttgc tattgtatta
    11821 ttactgacag ggattcggat tggagaggct gcttttttac catcagatgt tgattttgat
    11881 aaggggattt tacatattga taaggctctc caatatcatg atttaaaagt tgatgaattt
    11941 tattttgata cgactaagac cgtcaatgct gatagagagg tagccctccc aatagcagcg
    12001 agtgaagcaa tccagagaac tataaaaaga aatcaggaat ttgaagccta tatggaacaa
    12061 aatcctagtc ctgctttcaa aaagtgtgat agtgtatttc aaactgagta tggttctccg
    12121 ataacttctc actcatttcg tcaagttttg aagagggttg aggagaagtt gttaaaaaat
    12181 tgtcagaagg attatggttt taaatgggtc aagcatgtga cccctcattc tttcaaacat
    12241 atgcacatta gttatcttca aagtaatgaa atgcacatag ctgtaaagga tattatgact
    12301 agagttggtc atgcgaattt tgaaaccacg atgggctaca cccataacat cagtcgttca
    12361 caagaaaata ctgtaactgc tttaaatcaa tttgtagaaa agcacaattt tcactttaaa
    12421 gaattgaaga gttacacctg taaatattcg agaatgattg aacaattcat tgaaacttgt
    12481 gatgataaca ataaagtaga gttaagtgtt gatgaattta aagacttatt acaccttggt
    12541 tcacgttact cacccaaaca tattgtttca aatttactgt taaaaatcaa aaaagatatt
    12601 gtcaaatatc acccacagtt tgatataaag attgtgaaat taagcgggaa tcaaatcaaa
    12661 ggtttttcca tttcgtggta gttttggtgt tcgcttggtg tttagacgat agtaaaataa
    12721 atgaggggtg ctaaaccctt gctacgaaag gaaaaaactc aatggctact attcaatggt
    12781 ttcctggtca catgtctaaa gctcgtcgac aggtgcagga gaatttaaaa tttgttgatt
    12841 ttgtgacgat tttagtagat gcacgcttgc ctctatctag tcaaaatcct atgttgacca
    12901 agattgttgg tgataaacca aaactcttga ttttaaacaa ggccgacttg gctgatccag
    12961 caatgaccaa ggaatggcgt cagtattttg aatcacaagg aatccagacg ctagctatca
    13021 actccaaaga gcaagtgact gtaaaagttg taacagatgc ggccaagaag ctcatggctg
    13081 ataagattgc tcgccagaaa gaacgtggga ttcagattga aaccttgcgt actatgatta
    13141 tcgggattcc aaacgctggt aaatcaactc tgatgaatcg tttggctggt aaaaagattg
    13201 ctgttgttgg aaacaagcca ggggtcacaa aaggtcaaca atggcttaaa accaataaag
    13261 acctggaaat cttggataca ccggggattc tctggcctaa gtttgaggat gaaactgttg
    13321 cacttaagtt ggcattgact ggagctatca aagaccagtt gcttcctatg gatgaggtta
    13381 ccatttttgg tatcaattat ttcaaagaac attatccaga aaagctggct gaacgcttca
    13441 aacaaatgaa aattgaagaa aaagcgcctg tgattattat ggatatgacc cgcgccctcg
    13501 gtttccgtga tgactatgac cgtttttaca gtctcttcgt gaaggaagtc cgtgatggca
    13561 aactcggtaa ctatacctta gatacattgg aagacctcga tggcaacgat taaagaaatc
    13621 aaagaattcc ttgtgacagt caaggagtta gaaagcccta tttttttaga gcttgaaaag
    13681 gataatcgct caggagttca aaaggaaatc agcaagcgta aaagagccat ccaagctgaa
    13741 ttagatgaaa atttgcgctt ggaatccatg ctttcttatg aaaaagaact ttataagcaa
    13801 ggattgacct taattgcagg tattgatgag gttggtcgtg gtcctcttgc tggtcctgta
    13861 gtcgctgcgg ccgttatttt acctaaaaat tgtaagatta aaggtctcaa cgacagcaag
    13921 aaaattccta aaaagaaaca tctggagatt ttccaagtcg ttcaagacca agccttgtcg
    13981 attggaattg gtatcataga taatcaggtc atcgaccaag tcaatatcta tgaagcaacc
    14041 aaactagcca tgcaagaagc aatctcccag ctcagccctc aaccagagca ccttttgatt
    14101 gatgccatga aactggactt gcccatttca caaacctcca ttatcaaagg agatgccaac
    14161 tccctctcta tcgcagcagc atctatagta gccaaggtaa cacgtgatga attgatgaag
    14221 gaatacgatc agcagttccc tggctatgat ttcgctacta atgcaggata tggcacagct
    14281 aaacatctgg aaggcctcac aaaactagga gttaccccaa ttcaccgaac cagctttgaa
    14341 cccgttaaat cactggtttt aggtaaaaaa gaaagttaat tgaaaggaaa taccatggag
    14401 gaacaatcgg aaatagtccg ttctaagaaa gaattcgcct ttgcatccag cactatacta
    14461 tcccaagttg gtcgaggaat cattgtcggc ctcatcgttg gaattatcgt cggatccttt
    14521 cgtttcttaa ttgaaaaggg cttccacctg atacaaggag tttatcaaga tcaagggtac
    14581 ttagtgcgca atctttttgt actggttttg ttttatatac tcatctgttg gctcagtgcc
    14641 aaactaacac ggtcagaaaa agatattaaa ggctcaggaa ttcctcaagt cgaagccgaa
    14701 ctgaaaggcc tcatgtccct caactggtgg ggcattcttt ggaaaaaata tgtgctaggt
    14761 attcttgcta ttgccagtgg actcatgctg ggtcgagagg gacccagcat tcaacttgga
    14821 gcagttggtg gtaaaggaat tgccaagtgg ctcaaatcca gtccagtaga ggaacgttcc
    14881 ttgattgcta gtggagctgc agcaggttta gccgcagcct ttaatgctcc tattgcagca
    14941 cttctctttg ttgtagaaga agtctatcac catttttcgc gctttttctg ggtctcaact
    15001 ctagcagcca gcatcgtagc aaactttgtg tctctactca tgttcggttt gacaccagta
    15061 ttggatatgc cagataacat tcctcccatg accctagacc agtattggat atatctcgtc
    15121 atgggaattt tccttggatt ttcaggtttt ctctatgaga aagctgtatt aaacgttgga
    15181 agagtttatg acttgattgg tcaaaaaatc catttggata gggcttatta tcccatcttg
    15241 gcttttatcc ttatcatacc agtcggaatc ttcttacctc aaatcattgg tggcggaaat
    15301 cagcttgtcc tttctttaac tgaacaaaat tttagtttcc aagttttatt agcttacttt
    15361 ttgatccgct ttatttggag tatgattagc tatggaagtg gactgccagg aggaattttc
    15421 ctccccattt tagctcttgg ttctttgctt ggtgccttag ttggtgttat ctgtgtcaat
    15481 cttggacttg tcagtcaaga gcaattccct atatttgtca ttctaggaat gagtggctat
    15541 tttggagcca tatcaaaagc tcccttaacc gctatgatcc tcgtaactga gatggtagga
    15601 gatattcgca acctcatgcc acttggtctt gtcactcttg tttcttatat tatcatggat
    15661 ttgctcaaag gtacgccagt ctatgaagcc atgctggaaa aaatgcttcc agaagaagta
    15721 tctagcgaag gagaagttac acttatcgaa ataccagttt ctgataaaat tgctgggaaa
    15781 caagttcatg aactcaactt accacacaac gtcctcatca caactcaagt ccataatggc
    15841 aagagccaaa cagttaacgg ctcaaccaga atgtatctgg gtgatatgat tcacctggtt
    15901 attccaaaaa gtgaaattgg aaaagtcaaa gatttgttgt tgtagtatga gcatttacat
    15961 aatttatgtt atgtaaatgc tcagcttgat ttatttagaa aaccgattct cagaaatgag
    16021 atcggttatt ttttactgat gaggaatttt acatataaat aattgaactt tattaaaaat
    16081 aagactataa ttaattaagt tagaaatgat aaagcataaa gctagaaagg agtttactgt
    16141 atcaaatctg tacagtaaga ttaaaatcat gaaaaagaaa acaatagtaa ttatagtgaa
    16201 atgaaataga aataggataa aacaaacagg acaatcaaat caatttctag caatgtttta
    16261 gaagtccaga tgtactattc tagtttcaat ctattataca atgtgttttg tatctcatag
    16321 ctccttatat agctcttcag ttatgtagta ttaacagaag tttagtgggt gagattttca
    16381 ttattttcct tattctgttt tgtttgtagg tctaagtctt tttatcactt tgaaaaactc
    16441 ctataacatc tttctgaaaa actataattt tcttgaaaaa tatacaagtc tatgctatac
    16501 tactagtata cttacttatg gagaaaatac atgaaacgtg agattttact ggaacgaatc
    16561 aacaaactaa aacaactcat gccctggtat gttctggaat actaccaatc taaactggct
    16621 gtgccctaca gttttacaac cctgtacgaa taccttaagg aatatgaccg atttttcagc
    16681 tgggttttgg agtctggtat ttcaaacgct gataaaatat ccgatattcc tttatcagtt
    16741 ttggaaaata tgtctaagaa agacatggaa tcctttatcc tttatctacg tgaacgtccc
    16801 ttgctgaatg ctaatacaac aaaacaaggt gtttcacaga caactatcaa tcgaacctta
    16861 tcagcacttt ctagtcttta caagtatcta accgaggagg ttgaaaacga tcagggggaa
    16921 ccttatttct atcgtaatgt aatgaaaaaa gtttcaacca agaaaaagaa agaaaccctt
    16981 gctgccagag ctgaaaatat caagcaaaaa ctctttctag gtgatgaaac agaaggtttt
    17041 ctaacttata tcgatcaaga gcacccacaa cagctttcaa atcgagctct ctcatcattc
    17101 aacaaaaata aagaacgaga tttagccatt attgcccttc tcttggcatc tggtgttcgc
    17161 ttatctgaag ctattaatct agatctaaga gatctcaatc taaaaatgat ggttattgat
    17221 gttactcgaa aaggtggcaa acgtgactca gtcaatgtcg ctgcttttgc taaaccttat
    17281 ttagagaatt atctggccat tcggaatcaa cgctataaaa cggaaaaaac agatacagcc
    17341 ctttttttaa ctctctacag aggtgttcct aatcgtatcg atgcttctag cgttgagaaa
    17401 atggttgcta aatactcaga ggattttaaa gtacgtgtaa caccccataa actgcgccat
    17461 acactagcaa ctaggctcta tgatgctact aaatcacaag ttttagtcag tcaccaacta
    17521 ggacatgcca gcacacaagt cactgacctc tatacccata ttgttaatga tgaacaaaag
    17581 aatgctctgg atagtttatg attttacgta ttttaaatta tgtaaataaa tatcaaaaaa
    17641 agaagttggt tagttggcca acttcttttt gatttatcca actaccgctt cagcgatttc
    17701 ttcacggcta ataccagcga agtagcgtgt gatatcaatg gtttttagcg ccttaagaac
    17761 atcttcgcgt tcgtatttca ccccacgaag gacatcttct actgcagcaa cgtcttcaat
    17821 accaaagaag tcaccataaa tcttgatgtc ttggattttt gattcagtaa cgttagcaaa
    17881 gacttcaacc ttaccactag tgaatttggt tccacgacgg acgttaaatt caggtgattt
    17941 accatagttc cagtcccaag ttccaaactt agtatccttg atgcgattga tttcggccaa
    18001 ttcttcttct gaaaagacgt attcagtcat ctctgggtac tcttttttca tgtattccaa
    18061 gagtaaatca cggaattttt cgactgtgat tttttttggt aattcattga taatattggt
    18121 tacacgggca cggacggatt tcacaccttt tgattcaaat ttatcttttg aaaccttaag
    18181 ggcatttgcg aggactgaca aatcaacgtc aaagagcaag caaccgtggt gcatgatacg
    18241 gccgttgata taggcttggg cattgccaca gaacttctta ccatcaatct caaggtcatt
    18301 acgacctgtg aactcagctt taaccccaag ttgagccagg gtattgataa ccggagttga
    18361 gaagctcttg aagtcaaatg ccttattttc atcttctttg gagatgatcg tgtagttgag
    18421 gttatttaaa tcgtggtaaa cagctccacc accactaata cggcgaacta cctcaatacc
    18481 attttcgcga acataatcac ggttgatttc ttcgatagtg ttctggtgac gaccaacaat
    18541 gatagatggc ttgttaatcc aaagtaggaa gatttgatcc tcatccaaaa ggtgtttaaa
    18601 ggcgtattct tccaaggcaa tattaaaagc agtgtcattt gaatgattga taatgtattt
    18661 catgatatcc ctttacttta tatgatagaa actggaaata accttccagt ctaatctatc
    18721 tttgttttat tttttcttag gtgaatggat ggccattcct agaacatctg caaacgcttc
    18781 gtacatcact tcagagtaag ttgggtgccc gtggatggtc ttcagcattt cctcaacagt
    18841 gatttccatt tcgatgatgc ttgatgcttc gtttattaat tctgcggctg caggaccaat
    18901 aatgtgtaca ccaaggattt ctccgtattt cttatcagtg ataactttta cgaaaccttg
    18961 agcagcgtca gatgcaatag cacgaccgtt agcagcaaag ttaaacttac cgatggcaac
    19021 atcgtatttc tcacgggctt gttcttctgt caaacctact gctgctactt cagggagagt
    19081 gtagatggct gcaggagtca aattcaattt ggcaactgca tgatttcctt taagggcatt
    19141 ttcagcggaa acttcaccca tgcggaaagc tgcgtgagcc aacatcttag taccgttgat
    19201 gtcacctggt gcataaatgc ctggaactga agtttccatg tattcgttga ccttgataca
    19261 accacgatcc aattcaaact caacctctcc aataccttca aggtctggca tacgaccaat
    19321 tgaaagaaga gctttgcttg cgatgatatc gtcttttcct tcaaccttga tacgaagttg
    19381 accattttcc tcaatgattt cttgcagttt agtaccagtc aagatggtca ttcctttacg
    19441 ctcaaggatc aagcgaaggt tcttagaaac ttccgcatcc atagctggaa ctatacggtc
    19501 catcatttcg ataacagtca cttttgaacc aaatgtcatg aaggcctgac cgagttcgat
    19561 accgacaact ccaccaccga tgataacaag gctttctggc acttcgttca tttcaagaat
    19621 gtcatcacta gtcatgacaa gtgaagattc cataccaggg acgttgatct tgctgacttt
    19681 tgaaccacca gcaagaatga ttttcttggt ttcaagcaat tcagaaccat ttaccaagac
    19741 gttcttgtct ttagtgattg taccaattcc tttatgaaca gtaactccgt agctacgaag
    19801 aagtcctgca acaccaccaa caagagtatt aacaacttta gatttagttt ctaaaagttt
    19861 ttccatatca acagtgaagt taggattttc aatcacgata ccacgatttg cagcatgacc
    19921 gatattttca ataatttcag cgttatgaag gtaggtcttg gttggaatac atccacggtt
    19981 taagcaggtt ccaccaagtt cagatttctc aacaagggca accttaccgc cgagttgggc
    20041 agctttaatg gctgcaacat aaccagcagg acctccacca atcacaacga tatcaaaagc
    20101 atcatcgctc ttaccatcat cgtttgaggt acttgctaca ggtacagggc tagcttctgg
    20161 cgatgctgct ccagctgttg ggatgttttc cctttcttca ccaaggtaac cgataacttc
    20221 cgttacaggg acagtttcac cctctccttt gagaatggca atcaagtacc catcttcttc
    20281 ggattccaat tccatgctga ctttatcagt catgatttcc aaaaggattt ctccttcttt
    20341 tacaaattct ccgacttttt tattccattg gacgatttgt ccttctgtca tatccacgcc
    20401 ggcttttggc ataattactt ctaaggccat gtcttccttc ctttatctat atcttaaaaa
    20461 tgaatactct tgctcttaaa tcaacattga gattggggtt tcaatcaact ctttcaagtc
    20521 cttcataaac ttagcaccag ccataccatc tacgacacgg tggtcaatag ttaatcctaa
    20581 actcatgatt gggcgaatca caatttcacc attgacgaca actggcttct cgattgtcga
    20641 actgacacca aggatagctg agttgggttg gttaataatc ggaccaaagg actgaacacc
    20701 aaacattccc aaattactga ttgtgaatgt tgaattttgt aactcacttg gagccaattt
    20761 accatccaag gtacggccaa taacatcctt aaaggctaca accagttctg aaagactcat
    20821 cttctcagca ttgtaaacaa caggtgtcat caatccatta tccatcccaa ctgccatggc
    20881 aagattgaca tagttgtgag tgataatagt cttgccatct tctgtcaatg aagcgttgat
    20941 gtatggatgt ttcataagag tcttaacaac tgcaagtgaa agaaggtctg ttacagtagt
    21001 cttcttccca gttgcttcca tgattggctc aagaaccctc ttacgaagag ccaacatttc
    21061 agtcatatca acttcatagt tgagggtgaa ggttggcgca gtcaagtaag attcaaccat
    21121 gcgttgggca ataaccttac gcattggtgt cattggaata cgctcgattt caccatatgg
    21181 tgttacgtta tcagggactt cttccacttt ttcaatctga gcaggagatt tgatgctatc
    21241 gttttcgata ttttcaggaa gcagggccaa aacatccttc ttcatgattt taccacgatg
    21301 accggttcct tggatttcct gccaagcaat gttatgttcg agggcaattc gttttgcaag
    21361 tggcgaaatg cgaaccacgt ttgtgtcttt ataagtttcc acgtcttctt tgtggacacg
    21421 accgtttgca cctgagccag aaacgtcgta gaggtttatc cctaaatcat ccgctaactt
    21481 tctagctgca ggagtcgctc ttagcttgtc atcagccatg acctctccaa ttctatttat
    21541 gatacaaagg gcgtcaaaag cgactgaaaa ataggaaatc gacgatggct tcgatgaagc
    21601 caaggagatt tatctttttt ccgagctttt agcccgtgct ctaatctaag atattaatga
    21661 cgaagagctc tgcacctaaa agatacaaag tttctcgtca gctttatttt atttacataa
    21721 cttatcttat gtaactctat tctttgttat aagtttttcg gattgcatct ttgatacttt
    21781 caactgttgg aatcattgca ttttctaggt tttgtgcata aggcatcggc acatcttctc
    21841 ctgcacaacg gcgaattggt gcatctagat agtcaaatgc ttctgattct gaaataatag
    21901 ctgaaatttc accgatatag ccacttgttt tgtgggcatc gttgaccaga acaaccttac
    21961 cagtcttctt cactgagttt atgatgatat ccttatcaag cggaacaagg gtacgtgggt
    22021 caacaatttc aactgaaatt ccttcttctg ctaattcttc agcagcttga accacacggc
    22081 gaagcatttt tccataagta acaactgtta catccgttcc ttggcgtttg atttcaccaa
    22141 ccccaagtgg aattgtgtag tctggatcaa ctggcacttc ccctttttgg ttaaattctg
    22201 acttgtactc aagtataata actgggtttt tatcacggat agaagactta agcaggcctt
    22261 tcatgtccgc aggtgttcca ggtgccacaa ccttaagtcc tggaatgtga gtaaaccaag
    22321 actctagaga ttgtgagtgc tgggcggcag agccaactcc gttaccagct gcacaacgaa
    22381 cagtcattgg aacctgacct ttaccaccaa acatgtaacg tgttttagca gcttggttga
    22441 cgatattgtc catggcaata acagagaagt ccatgaaggt catatcgacg attggacgaa
    22501 gtcctgtcat ggcagctcct gctgctgctc cagagatggc agcttcagaa atcggacagt
    22561 cacggacgcg ttctggacca aattcttcaa gcattccaac agaagtaccg aagtctcctc
    22621 cgaagacacc gacgtcttct cccatcaaga acacattttc atcgcgacgc atttcctcag
    22681 acatagcaag gataatggtg tcacggaagg acattgtttt tgtttccatt ttatctcttt
    22741 ctccttagtc tgcgtaaata tcttcaaagg ctgattcaag cggtgggaat gggctttcct
    22801 ctgcaaattt aacagaagct tctactgctt cctttacttg cgcttggatt tcttccaatt
    22861 cttcggcact tgcaatgtta ttttcaataa ggtaattgcg gaggttttcg attggatctt
    22921 tttgtttcca caattccact tcttcacgcg tacgatattt accagggtca gatgatgagt
    22981 gaccgagcca gcgataagtt acactttcaa tcaagactgg accattgcca ctgcgaacat
    23041 ggtccacagc tttctgaaat ccttcataga catcgatgac attgttacca tcttcgatga
    23101 acattccagg aattccataa gcggcgctac gttgatggat atgttctata ttggtcattt
    23161 tcttgatatc cgcagagata ccgtaaccgt tgttaatgca atagaaaatg actggcaggt
    23221 tccagataga agccatgttc actgcttcgt ggaaaacacc ttcattggtc gcaccatctc
    23281 caaagaagca gacaacgatt ttaccggtat tttgcatttg ctgactgagg gctgcaccga
    23341 cagcgatccc cataccacca cctacaatac cattggcacc aaggttccca gcatcaaggt
    23401 cagcgatatg catagatcca cctttccctt tacaggttcc agtgtattta ccaaggattt
    23461 cagccatcat tccgttgagg tcaatccctt tagcaatagc ttgcccgtgt ccacggtggt
    23521 ttgaggtaat cagatcatct ggattgagag ctaacatagc ccccacgtta gctgcctctt
    23581 caccaacaga aaagtgcgtc attcctggca ctttcccttt ctttactaat tgtgcaattt
    23641 ttaagtccat gcgacggatt tcttccatct tacggaacat ttctagcaaa agatttttat
    23701 ctaaagttga catcttcttg cctttctaac tttcttctta ccttactatt ttaccgtttt
    23761 tggcaaatac tgtcaaagtt tttctaaaag aaatttcaca aaataaaaaa gaaaaccccg
    23821 tgaaaacaag ggattttctt atcaagaata ttttttcaca aactttttag cgtttggatt
    23881 ttgctaaaga ttcaaatctc ttcataatca cagttaaacg ccaacggtag agcgccccac
    23941 tcacaatcaa actaataatc aagccgatcc agtaagaata agctccaaaa tctgttagag
    24001 aatcaaatag cgtagccaca gggattgcta cgccccaata accaagcaaa ccaaggtaaa
    24061 aaggaataac tgtatcctta tacccccgca aaattccctg aagcggcgcc gcaaaggtat
    24121 ctgctaactg gaagaaaaga ctataagtta aaaaacgcac tgtcaaatcg ataaattttg
    24181 ggtcgttacc ataaagactg gccacatttc ccctaaaaat gtaaaggaag gttaaggtga
    24241 aggccgcaaa aatgagggca gtccatcttc ctagaccaat ataggttttc gcatcatcaa
    24301 atcgcttggc tcccacttca taggaaacga caatagccat agccgatgag atactcatag
    24361 gaaaggcgta cataagactt gaaaagttca tagctgactg gtgactagct ataatcaagg
    24421 acgaaaactt agccataatc aagccaacca ctgaaaagat agccacttcc gcgaagacag
    24481 ttcccccaat aggcagacct aaacgaactc cttccttaat tttatccata ttaagtggaa
    24541 ttcgtttctc aaggtgtaag gctttgagct tctcctgttt aaataaaacc agaacagaaa
    24601 tcccaagcaa gacccagtag gccaaggatg ttcctaaacc agcaccagcc cctcccagtt
    24661 ctggaacacc aaaggcaccg taaatcaaga gatagttaaa tccgctattg agagggagta
    24721 acaaaagcat gaggtacatg gacagtttgg tcaagcccag cgaatccagc aaggaacgaa
    24781 tgacgctaaa gagcaacaag gggataatcc cgatagataa aaaccaaaga tagcgaaccg
    24841 ctactgccgc tactgctgct tctaacccaa tatgattcaa gattgttggt gccaagaaaa
    24901 gtaccatccc cagcaatacc acagataggc ccaaggccaa ataaataaat tggtaaaaat
    24961 cagacgcaac ttcttccttt tttcctcgac caagatggtg accaatgata ggcaccaagg
    25021 ctgacacaat ccctgttaga aatgtaaaga aaggattcca gatactggtt gccatagata
    25081 caccagccaa gtccatagtg ttgtattgac ctgtcattgc agtatcaaca aaagaggcag
    25141 aataattggc aaattggtaa atcaggattg ggaagaaaat ttttaaaaat aatactaact
    25201 tctctcgtaa acactttgtc ttatacatac ttctctttct attctgattt atctaaacca
    25261 aagagtttca gaccatagtt tttcaaactt agcggaggtt tattagattt tgaagtagta
    25321 tgccaacacg cacatgtacg acaataatag cttctaacta aacctccgtt atcatattga
    25381 accgcatggt cagctttttc tttagtttca tattgaattt tggaacgatt agctgcggga
    25441 cagtaaattc cactattaga tttcgcttgt ctctccctac gttttcgaaa ataattcata
    25501 ttctaactcc tatcaagctt gatagacgat ttgtccctta cagatggtat atttaacctg
    25561 cccttttaag gtttcaccga tgaatggtga attagctgct ttggaagcaa aatgggagtc
    25621 cacaaggcgg tcagccttgg catcaaaaat agtgatatct gctggaccat tctcagccaa
    25681 gtaacctgct tcaaagttgt aaagcttggc tgggttgtat gtcatttttt caagtaattc
    25741 catcaagctc aactcaccag cttctactaa ataggtcaag ctgagagaca gggatgtttc
    25801 taagccagtc ataccagatg gcgctttggt aatatcctca acattttttt catctacatg
    25861 atgaggcgcg tggtcagtcg caataactgt gatgacacct gatttgagac cttcgataac
    25921 ggcacgacgg tctgattcca aacgaagcgg tggattcatc ttagcattgc taccttgtgt
    25981 taaaaaaagt gcttctgtct tagagaaatg ctgtggcgct acttctgctg tgacttctgc
    26041 acctaacccc tgagcaaact ccactacttt aacactttct tccttagaca aatgctggat
    26101 gtgaacatgg gctttagttg cataggcaat catgacatca cgcgccatca tagcgtactc
    26161 agccacccca gtagcaccgc agatatggaa atgttctcta gcaatatttt cattaaagcc
    26221 aagaacaccg ttcaaacctg gatcttcctc atgaaggctg ataaaggtat tgagtttttt
    26281 ggcttcctcc atggcttcct tgacaatctt actgctctca agcggaatac cgtcatcaga
    26341 gaaaccagcc gcaccagctt ctaagagcgc cttaaagtca gtcaagtttt taccattaaa
    26401 gtttttagta atggtcgcaa ctgtcttgac attaatcttc tctttggcag ctgactggag
    26461 aactgcttgc aaagtctcca cgtctgaaat ggttggactg gtattagcca tcatgacgac
    26521 agtagtaaaa ccacctgcag cggctgccag ggcaccagta tgaatgtctt ctttatgtgt
    26581 ttgaccaggt tcacggaaat gcacatgaat atcgaccaaa ccaggagcaa ccacaagacc
    26641 agtagcatca atcgtttctg ctccttcttc cgtgatctca ggcgcaattt tgataatttt
    26701 cccatcttga actaagacat cacaaacttg atccaaacca gacttgggat ccattacacg
    26761 accatttttg attagtagca tctgctttct cctttattca tagaaatcaa cttgggtatc
    26821 caacaattta tccccatcat aaacaaactt ggctgaaaag aagggtttat cctctaaaag
    26881 ccactcaaca aaggtgtggt caccttccca agtcggcttg ctcaaaacct catcataggg
    26941 aacccattct agcgtcccct cattgcagtc aatcaagtcg ccctcaaact ccgtcacctt
    27001 aaaaacatag gtgtaccagt ctaaatctgg tgtaaattca ggaaaagtga tgacaccttt
    27061 tagaactggc ttggctttga gccctgtttc ttcaaggatt tcacgcgccg cgcattcctg
    27121 gggcgtctct cctctctcta gcttaccacc cacaccaatc catttccctt catggacatc
    27181 attgggtttc ttattacgat ggagcatgag cagttctttc ccattatcaa tgtagcaaat
    27241 cgtcgctaac tgaggcatat tttctcctta tctaagccaa tcgattggct cttgtcctgt
    27301 ctcttttaag aatgcattgg ccttggaaaa gggcttggaa ccccaaaatc ctctataaac
    27361 cgacaaagga cttggatggg ctgattcgat aatcaagtga tgaggattgg taactaatgc
    27421 cttcttctta cgtgcataag ctccccagag tacaaaaacg actggtctat ctagatgatt
    27481 gaccacctga atcacagcat cagtaaaagg ctcccagatt tgaccagcat gaccattggc
    27541 ctgtccagca ggaacagtca aacaagcatt aagaagcaag actccttgct cagcccaagc
    27601 tgtcaaatca tgagatttct taactccgat atcatctgac aattctttca agatattttg
    27661 caaggatggt ggagctggga tagagtcagg tacagaaaaa ctcaagccct gcgcttgacc
    27721 tggtccgtga taggggtctt gccctagaat taccacctta acttcttcaa gcagtgttgt
    27781 caagagagcc tgaaaaacct tttccttggg tggataaata atcccctgag aatagacctg
    27841 ctccataaac tgattgattt tcccgaaata accctcaggt aattgcgcct taatcaaagc
    27901 atgccaagac gagtgttcca tagccgactc cttcattttt actgcctcta ttatagcaaa
    27961 aagtggctat ggaaaccact ttttacagtt tatctaaaga tttaataaat cgactatata
    28021 tacgatttga atacgtgaat acagtttata aagactggct attttttata attacttttt
    28081 aaatcattaa gcattttact acctctttcg aagattatct tttctgaaat atttttaaac
    28141 atattaaaat ccatttcaga aaaaggagtt tctttagaaa cttgccatat agtctttaaa
    28201 taattttttt ctaaaaagtc gtcaaaatta gaaaaaaatc gaaaatacaa tgcattctct
    28261 tggtgtaaaa tcgctctttt taaaggataa tactctttaa tattattaac tttttgttcg
    28321 taggcatatt ttgctacatg atctaggtat atatcaaaaa agtcatgagg aaaatctccc
    28381 atacagccat tacgattcat attgaggcta tattttcgat tagtaagata attcggaaat
    28441 atatttccta ttactctaag attatctact tgtgaatccc ttctcccaat ataatcccct
    28501 tctttgacta atgatggaga tttccaagta aaaattaaat cgtcagagaa atttttctta
    28561 tcaaaaaact taaaaagaga ttgataaata ctatttgcta attgacaagt gtcagatgta
    28621 aattcataat taacagcttc attaaaatca acttcagaca tttcaatgta ctcttcaata
    28681 gtaatattag ctttttttgt agtcattagc taatctcctt taaaatgtga tcttttcaag
    28741 aatattttta tctaaacaat ccagcaagtc ttggtaagaa tagacttcgt aagtcggctg
    28801 ggcttgtgtg tgattttcga ggtgatgagg attataccag atagtgtcaa tccccgcatt
    28861 attgccacct tgaatgtcgg cggttagaga atctccaatc atcagcgtct tttctttact
    28921 aaatccagca atttgctggc caatcttttc ataaaagaga gcatccggct tttgagtttg
    28981 caactgttct gagataaaga cttgattgaa ataaggtact agaccagatt gagccaaacg
    29041 tcctgtctga atggcagtaa tgccatttgt cgcagcatac aagttataat cacgctcaat
    29101 gaggctgtcc aagagatcat gagcgcccga tagtgtttgt ccctgctgag cgagataaaa
    29161 ttggtaacgc tgggcaagaa aactaccgtc tttttcctgt ccaaaatgag aaaataaacg
    29221 agaaaagcgc gtgttaacca gctcttgttt actgattttc ttcagctcca agtctttcca
    29281 gagagccttg ttcataggaa cgtaataatc tttataagcc tgaatatccg caactccttc
    29341 ttcttttaga agttgggtca aagccacatc ctcagcagca tcaaaatcaa gaagagtgtg
    29401 gtcgaggtcg aagagtagaa atttgtagaa caatttgagg ttttcctttc tgaaaattca
    29461 ttaagaacat tatatcataa agcacctcat acaattaact aatttaatca cttaaaaaaa
    29521 attcgaacac tttctataca actgacagct caaatctttc agaatagaac aatactaact
    29581 atcgagcacc ctgtcttcat aaatatatgt gtaattctag acctagaatt cctataaact
    29641 aaatgctttc atactcttcc aagtaattga ttgccttaaa ttttaatttt tgaaggattc
    29701 taaagctaga atagtcccat cacaatcagt tttgattgat tcacaattta gaaacactat
    29761 agtttcactc ctgttaaaat aaaaaggaac tgcataaagc aatccctttc tgattttgaa
    29821 atcatttact taacatttta tagttgagat aatcaatagc ttacctataa aaagagttat
    29881 agtaaaattc cttatttatt gatttcaagc tccgctaact gtgtttgaat aactgacagt
    29941 tctgcaccag cctgaagaag agcagctgca ttataggcac cttctacaat tggaaccctg
    30001 ttgatgatga tacttttatc actgaaatca gtcaccattt ttaagttcat tttagcagaa
    30061 cctaggtcaa aaaaggcaag taaagtatct gctggatttt cggaaacaac cctatctact
    30121 tgatcaaaac tcgttccaat tcctccgccc tcggttcctc ctacataagt aatcggaaca
    30181 tctttagcta ctttactaat cagttcaaca acaccttctg caatgtgttt ggaatgtgaa
    30241 acgataacaa gaccaatacc aatactttcc atcaaaccac cccagtttct aaaatagcag
    30301 taaagagtaa tcctgatgag aatgatccag gatcaatatg tccaagaaac cacatgctcc
    30361 taagacaaga gctaacagac tggccatcaa taatagtatt gttctttttt tcatcattac
    30421 tccttaacta gtgtttaact gatcaattag ccagtaaata gtttatcttt atttacacta
    30481 tctgttaaga tatagtaaaa tgaaataaga acaggacagt caaatcgatt tctaacaatg
    30541 ttttagaagt agaggtatac tattctagtt tcaatctact atattttgca cattttcatg
    30601 aaaaaaatga gaactagaac tcacattctg ctctcatttt tcgttttccc gttctcctat
    30661 cctgttttta ggagttagaa aatgctgcta cctttactta ctctccttta ataaagccaa
    30721 tagtttttca gcttctgcca taatagtatt gttgtcctgg gtgccaaata gtaaattatt
    30781 ttttaatcct gtgagagtct ctttggcatt ggacttgata attggatcct ggatttttcc
    30841 aagtaaatct tcagcctctc tcagtttttc ttcaaccttt tcagtctcga cctgaggttc
    30901 ttctgattcc tctggtgatt cttcttctgg ttcctctgtt ggttttggag actctggttt
    30961 ctcgctttgc ggtttctctt ctcgaggggt ttcttcctca ggtttttctg tctgaggttt
    31021 ctcctcgctt ggtttttccg tttgattggt atcagcttga ccatttttgt ttctttgaac
    31081 atggtc
//
LOCUS       DAVHKZ010000027        29985 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000027 DAVHKZ010000000
VERSION     DAVHKZ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29985
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.027"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..1620)
                     /locus_tag="VVO74_001440"
     CDS             complement(<1..1620)
                     /locus_tag="VVO74_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEU5695452.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKEIMNGDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVEYNDHLEITAYHISDDVMQRSITPVS
                     VTSQSCGMALSRMVQNTKTALGDFSFNSDIQDRRTFNTTETETLYSILLDGKHSIVGT
                     WEGELVRDNFAITVKKSRGENRGVVITTHKNLKNYQRTKNSQNVVTRIHAKSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKTVEELQKWAQSKFSNEGIDKVSDAI
                     KIEAYELDGQVVHMGDTVNLKSWKHNVDAFKKAIAYEFDALKEEYLSLTFDDKAGIGG
                     SRASGGLSSAADAILGVTESAQEIALEKALQNADLDFDHKAGLLRQEISDDIELAKAK
                     AEEVKRELSDTINQRFNSFDNGPLKETKRKAEEALRQAGASSSLAQEAKRIGLDSVAR
                     LEAFKSQTTSAQTALSGDLDALKRTIVNDIRPKQAQVEAEIAKQAEALSRTKNELAGA
                     SSSLAQEAKRIELDSVARLEAFKSQTTSAQTA"
     gene            complement(1621..2343)
                     /locus_tag="VVO74_001441"
     CDS             complement(1621..2343)
                     /locus_tag="VVO74_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEU5695453.1"
                     /translation="MTKINELTIDGVKTSSFKCEILVETRPQIIVSSSKTSLLEHDGI
                     SGAIVQSNRHRRLIEKSYHISLINPTDEDLYRFSSLLNREKFWLENEQEPSVKYWCYK
                     VDDFKIIKDDFGAWTVDVKFTCHPTKYFKGSDTQRLTRSGTLTVQGSALAFPKITIVG
                     QSAVETSFTIAGQVIRLEKLSESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            complement(2340..5078)
                     /locus_tag="VVO74_001442"
     CDS             complement(2340..5078)
                     /locus_tag="VVO74_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEU5695454.1"
                     /translation="MTETFEGLYVKFGANTVEFDRSVKGINNALSSLKKDFNNINRQL
                     KMDPDNVDLLNRKLLNLQEQARVGAMKIAELKKQQKELGESEVGSAQWNKLQLEISKV
                     ESQMKVVDQTMNSTKKHIEDVGNPKSILNLNKEINNVAKELDIVNQKLELDPKNVELS
                     EEKMKLLGKQSSLAKDKVQELKRKQEELGKEKIGTEEWRQLQNEIGQAEVEVLKIDKA
                     MGNLGDSSRSATGNIKEATGYLKADVMMNIAEKAGQLGQKMVDAGKKTVDAWSEIDEA
                     MDTVTTKTGLTGEALLGLQEIAKGIATSLPSATFQESADAVGELNTQFGLTGDTLQSA
                     AEYLLKYSKITGEDISNSAINAKKAIDAYGLSNEDLARVLDSVTKVGQDTGQSYDSIF
                     QKAIDGAPQIKMLGLSFKEGATLIGRFEKSGIDSSAALASLSKATVNYAKDGKTLTEG
                     LNETVNAIQNATSKTEAIRIASEVFGNRAAPKMVDAIQRGAFSFNDLAEAAQNSSGTV
                     ATTFAETKDPFDDLTTYSNKAKEGLAEIGGTLLETVIPALEPLMGMLESAVNWFTSLN
                     ETDQQTIVILGLVTTAVMLLLGAIAPLVIAIGAIGAPVGIVVAAIVAAIAAITLIIQA
                     IMNWGTISEWLQSTWDACAAWLSELWTNIVTTATTAWSSFTAWLSEIWSSVVSTGQSL
                     WSSFTSTLSNIFSSLISGAQSLWSSFTSTLSNLWSGLVSTGSNLFNNLSSTISGIFNG
                     ILSTASNIWNSIKSTISNAIDGAKNAVSNAIQAIKNLFNFNISWPHIPLPHFYVSGSA
                     NPLDWLSQGVPSIGIEWYAKGGIMTKPTLFGMNGNRAMVGGEAGAEAILPLNKSTLGA
                     IGQSIANTMNTSNSINVNFSGVTIREEADLNRLADVVGTRIAEELQRKTNLRGGFA"
     gene            complement(5265..5741)
                     /locus_tag="VVO74_001443"
     CDS             complement(5265..5741)
                     /locus_tag="VVO74_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000591561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695455.1"
                     /translation="MIKKELSFTAFDSYGEERERTETVRFLYSLPAIKMYEQRTGRNF
                     FDDNQKALTAYTQLALATGVNGRLSALTDEEKVKLMPLLMEPDFMNFLTEVIPCLYGE
                     VENGRLVQNELTAETASLAPWFGDLIDIGFFSDLFYEFNRSRAKVPQDRKKPQQKS"
     gene            complement(5743..6411)
                     /locus_tag="VVO74_001444"
     CDS             complement(5743..6411)
                     /locus_tag="VVO74_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEU5695456.1"
                     /translation="MTYKYDTREVTHGNTTGFFAKISKTESGTLDLKKPYPFTGLRKT
                     SFETSQESNAYYADNVEHVRLQGKKSTEGSITTYQIPKQFMIDHLGKKLTTSTPPALI
                     DTGVNANFIWGYAETVTDEFGSEVEEFHIWTNVKASAPKGSTTTDESSATPKEIEIPC
                     TASPNNFILDSDKKPVSEIVWRDTDKGVVRAKFDKLFASSTPMKLIDFINEALGTTAI
                     VPGG"
     gene            complement(6425..6769)
                     /locus_tag="VVO74_001445"
     CDS             complement(6425..6769)
                     /locus_tag="VVO74_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000534622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEU5695457.1"
                     /translation="MGSGSVNVKTLKIDIQNQVLEIIEKAGKSTAGDIRDGSPRRNGV
                     YEKGWTHETIEDIAVVYNNGKEKSLAHLLENGHATKNGGFVAPQEHIRPAYLKNKEIF
                     LNNMKSIKIRPN"
     gene            complement(6756..7103)
                     /locus_tag="VVO74_001446"
     CDS             complement(6756..7103)
                     /locus_tag="VVO74_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695458.1"
                     /translation="MAKKFFTRQEIQEILEKNTLKSKVFYMEREEKSSPDNVILYYRL
                     TPGSSITADDTVHMRKVTIQISHYHKKKLDSIEELMLSNFMCEPSQLNLKQPDTDYLL
                     TTYRIEVFTSGKW"
     gene            complement(7103..7408)
                     /locus_tag="VVO74_001447"
     CDS             complement(7103..7408)
                     /locus_tag="VVO74_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail adaptor protein"
                     /protein_id="HEU5695459.1"
                     /translation="MKSSRVSIILCYDERTEVEKGVFEKQVVEKKVKAEKEKIYQRRL
                     DKALADGQVLTARFRIRSNYVTDSLDYVKYKGKEYKVNVGTESDDDHYTIIELGELK"
     gene            complement(7405..7740)
                     /locus_tag="VVO74_001448"
     CDS             complement(7405..7740)
                     /locus_tag="VVO74_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000154006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695460.1"
                     /translation="MTILNQIKEMVEVDVEEEIFDTQFLSYINSGISYLTRNNIPINR
                     IDKESELTEWNEIEEDDKETILDWLHLRCVQRFDKSLMTGNSTTRSWIDEELTNILYQ
                     LKAIYGVKS"
     gene            complement(7766..9019)
                     /locus_tag="VVO74_001449"
     CDS             complement(7766..9019)
                     /locus_tag="VVO74_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000855225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEU5695461.1"
                     /translation="MKTLVELMEERQKHADELSEIKFKKASIEEKLESATIGEEELAQ
                     LKSDAEGLVSKADELKNTISKLDVEIEEKQDNLNKAAKSIKEVQKGKIQMEYLKTKEA
                     ALDFARILMDNEGSSNSARKAWEANLVEKGVTDVNKILPEPVLIAIQNAFNDYDGILN
                     HVTKDPRYAVRVALQTQQAKAKGHQNGKTKKDESFVFIDYTINSAAVYIKYSFEYADL
                     KKDTTGAYFNYVMNELAQGFIRAVERAVVIGDGKNSDDDDKITEIKSIAEETLAQLFD
                     TQEISVDGEFDSTVLENLVKGIDKLAANTTPILVTSKTIARKLKMVKDGEKRYIDPQP
                     FAPISQTGNVIAGYQVYVYDWMEDATNPIIAFADKAYKMIGDDVSADRFEDYDVTMNR
                     RHIELASVLGGRLGQYKSAVKFTKG"
     gene            complement(9033..9575)
                     /locus_tag="VVO74_001450"
     CDS             complement(9033..9575)
                     /locus_tag="VVO74_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HEU5695462.1"
                     /translation="MEKLKTFVVKSVEEESADFHFEAYASTYGNTDRDGDVMAKGCFD
                     NTLKTKAVVPMCLNHDRNRVIGKHELSVDEKGLRTRSTFNLSDPEAKKTYDLMKMGAL
                     DSLSIGFFINDYEPVDAKQPYGGWIFKEVEIFEISVVTVPANPQATIDNIKGFDMSVV
                     DKRIAQANMKQDIMSKLATI"
     gene            complement(9622..10764)
                     /locus_tag="VVO74_001451"
     CDS             complement(9622..10764)
                     /locus_tag="VVO74_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEU5695463.1"
                     /translation="MNKYINNLREVFARIFRPSNRKSTRTYLQRNLNYWRRNSIYLDN
                     IYNKISTDTAQVRFKHVRITRNPTGVDKMEWFENSDLANVLSFSPNPLEIPVVFWANV
                     TRAMLKDGVAVVVPRWENGRLIEIWFAKKTISWTAERVEIMIDDVEIELPLSDVWVFE
                     NPKLNVTSQLNQITELIDINLDALTEKLGRGNSKLRGFLKLPTKAADEHLKKQAKSRV
                     DSMMELAEIGGIAYLEQGEEFMELNKDYSTASKEEMEFLKSQLYHAHGINEKLFTCDY
                     TEEQYRAYYSSVMKLYQRVFSEEINRKYFTKTARTQGNKLLVFFDMADMISFKDLVEG
                     GFKSKYAGLMNSNEFRETYLGLPGYEGGEVFETNLNAVRIEPSESN"
     gene            complement(10773..12485)
                     /locus_tag="VVO74_001452"
     CDS             complement(10773..12485)
                     /locus_tag="VVO74_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEU5695464.1"
                     /translation="MVEMRYFDKYAQLVYSGKIRVCELTMKSIKRVERYKEQYIFKQE
                     EVDKRIEFIEEECSNTKGLAGKLHLALPQKVWLETTWGFYHTVEVTKTDPDTLEEYKD
                     FEERRLIHEVPIIVPRGTGKTTLGSAIGEVGQIIDGEWGADIQLLAYSREQAGYLFNA
                     SRAMLSNEESLLHYMREADILRSTKQGILYETTNSLMSIKTSDYESLDGTNAHYNIFD
                     EVHTYDDDFIKVVNDGSSRKRKNWITWYISTNGTKRDKLFDKYYNIWVDILDEKIVNH
                     SVMPWIYQLDDVSEIHNPDMWQKAMPLLGITTEKETIAKDIEMSKNDPAQQAELMAKT
                     FNLPVNNYLAYFSNEECKGWLDKFDKSLFVGNEERSARCVLGVDLSDVNDICSVSFMV
                     VRGEERQYLNKKFMPRHTIEGLPKELRDKYAEWELSGQLHVHELDYNDQAYIFEELRQ
                     FMSENRILPVAVGYDRWNAKELIRLINDYYGDICHDIPQTVKSLSNPLKVYKEKAKMG
                     KIIFDDPVATWNHANVRVKIDANNNVFPNKEKAKEKIDVFASQLDAFICYENFKEDLS
                     YYFD"
     gene            complement(12478..12963)
                     /locus_tag="VVO74_001453"
     CDS             complement(12478..12963)
                     /locus_tag="VVO74_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695465.1"
                     /translation="MILKINEVLEKLGISRATLTRYRKKLGIFEETRSNITKSQFKEL
                     EKLANQRQKYTREERVELSRKTFKLIPKEKMLEINDNDSVGLKNLKTQYNHNQKVIEN
                     FQLEINKVINDGELPDKYLLDGMEKYQKLNMQIMSTIEKQSPQGDSLKEMIQEKLARY
                     G"
     gene            complement(13100..13417)
                     /locus_tag="VVO74_001454"
     CDS             complement(13100..13417)
                     /locus_tag="VVO74_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEU5695466.1"
                     /translation="MTFKNPKHSDWFRTWQIKFYNSKPWRTLRNRIRSIKRMRCDMCG
                     RLIHGKSIVDHIIEIDETNYQDESITLNEDNLQLLCLECHNTKTFQSKINLNLENRNI
                     NLF"
     gene            complement(13847..14389)
                     /locus_tag="VVO74_001455"
     CDS             complement(13847..14389)
                     /locus_tag="VVO74_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU5695467.1"
                     /translation="MNIVEPLRDKDDIQAMKDYLSSWNEKYYMLFLLGINTGFRVGDI
                     LKLKVKDVQGWHIKVREQKTGKYKSIKMTRPLKNELREFVKDKELHEYLFQSRVGKNK
                     ALSYKTVYWFLKRAAEDLGIDNVGTHTMRKTFGYHYYKKYKNVADLMSLFNHSSPAVT
                     LIYICVRQDELDTKMSNFSL"
     gene            complement(14498..14962)
                     /locus_tag="VVO74_001456"
     CDS             complement(14498..14962)
                     /locus_tag="VVO74_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695468.1"
                     /translation="MGKKNLITARRDYLEFELNDKYLQIDKLIGQRRHELERLYEVKH
                     LTVPGIDDTGASGSGTFVNRSENLAVAYASDPMVLRLENFQTAISKLLDVLEPDDKKI
                     FHLKWGEHTRYDWIQVWHKMENGDTGYLYRHSKQIYRRREIILDTLAKLLFM"
     gene            complement(14999..15529)
                     /locus_tag="VVO74_001457"
                     /pseudo
     CDS             complement(14999..15529)
                     /locus_tag="VVO74_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670043.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            complement(15592..15765)
                     /locus_tag="VVO74_001458"
     CDS             complement(15592..15765)
                     /locus_tag="VVO74_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695469.1"
                     /translation="MEDEQNILEIQLILGKQVLEIVLDLLKDDSKTGVVLPLNINDRE
                     FTITVEKEVTDRD"
     gene            complement(15765..16052)
                     /locus_tag="VVO74_001459"
     CDS             complement(15765..16052)
                     /locus_tag="VVO74_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695470.1"
                     /translation="MTQTLEEGMKNQSKCIKVPREIRPFDIGYRIVNKYGQALALRNG
                     ASIFDLPFLAEKAIEKEFGKNDPDFDIGKHSVEEVAIVNLSKFHSYFEEVE"
     gene            complement(16052..16576)
                     /locus_tag="VVO74_001460"
     CDS             complement(16052..16576)
                     /locus_tag="VVO74_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEU5695471.1"
                     /translation="MNKQELIEKYKELENSSFDIAAIVVCQLVLKDLEQLDEPKPVKV
                     KQFVADWYEENKDSFEFNVWDWIAFRDEAKKSENREFNNWINNTRENPIQTLVNMHNF
                     GYEVEKEKRYLVKVKGVHFTNYLISGNRKDIWFFHSAYEPEHQIIAHTRKELEEAGFG
                     WVFDCPGIEIEEVE"
     gene            complement(16578..16892)
                     /locus_tag="VVO74_001461"
     CDS             complement(16578..16892)
                     /locus_tag="VVO74_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695472.1"
                     /translation="MEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMAE
                     DGMTFMGAMECIFADEKPTDYDLGATKDWLPKSKEFDDWVGYSPGMSQVVIAVYLIYR
                     GN"
     gene            complement(16867..17076)
                     /locus_tag="VVO74_001462"
     CDS             complement(16867..17076)
                     /locus_tag="VVO74_001462"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695473.1"
                     /translation="MKYDKQAEIDGLKRTIEQNEEKIIEYSKPCDARKRRIRALERDL
                     LRKKNKELRRKVEELEGDGRVKAKS"
     gene            complement(17063..17230)
                     /locus_tag="VVO74_001463"
     CDS             complement(17063..17230)
                     /locus_tag="VVO74_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695474.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEVR"
     gene            complement(17357..17584)
                     /locus_tag="VVO74_001464"
     CDS             complement(17357..17584)
                     /locus_tag="VVO74_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695475.1"
                     /translation="MLELYFVYNGHCKFYLGTFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGEKND"
     gene            complement(17584..17778)
                     /locus_tag="VVO74_001465"
     CDS             complement(17584..17778)
                     /locus_tag="VVO74_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695476.1"
                     /translation="MFILKHGTREDKPFLRSAIISVTGLDISCSEEKKAMRFISRAAA
                     LQVSKALRGSFGNFYPVEVE"
     gene            complement(17793..18563)
                     /locus_tag="VVO74_001466"
     CDS             complement(17793..18563)
                     /locus_tag="VVO74_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU5695477.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQERVNELANAENERERKYYLEKFSLYDEILKNATLDNFETPTEKEAEK
                     LAFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLIS
                     TDIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            complement(18557..18715)
                     /locus_tag="VVO74_001467"
     CDS             complement(18557..18715)
                     /locus_tag="VVO74_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695478.1"
                     /translation="MGILELIEQFEIDYYPLSYEKKTLLADQPIHQVVACLSEMASWH
                     ECGGRLVW"
     gene            complement(18703..19530)
                     /locus_tag="VVO74_001468"
     CDS             complement(18703..19530)
                     /locus_tag="VVO74_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEU5695479.1"
                     /translation="MSEIKWIKIKTDIFDDEKMCLIDASPDRDAIIVIWIKLITLAGK
                     LNTKGVLTISKNIVYTDEMLAQTFHRPLNTVRMALEVFEKFGMVEKIDGVIMLPNWEK
                     HQNIDGMEKIKEQNRNRAARHRQKQKLLAQNNESNVTDNVMDNVTVTHGNALDKELDK
                     DIEINNNKVMISSSLSENLKNSGIHLTDKSHQQLLDYVGLDGMSFDMLNRAVEKTSGS
                     HKPSFNYLIAILESWKKKGFTSIEQVDEDDRKYKEGKKSRQQNDKTSEQEVRDEWGF"
     gene            complement(19523..19816)
                     /locus_tag="VVO74_001469"
     CDS             complement(19523..19816)
                     /locus_tag="VVO74_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695480.1"
                     /translation="MEELIEWLETKEKLNREMISDEETSDFNLHLENDNDTMFMIKEY
                     LNDYNKLAKDYRILSSENRLLKLEKMELEGRHIYEDMRMKYRANRRKWGARYV"
     gene            complement(19832..20152)
                     /locus_tag="VVO74_001470"
     CDS             complement(19832..20152)
                     /locus_tag="VVO74_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695481.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     ASMIIRGYNHAYERGREAERQEIRKNIRRPFKGFTYDNEPPQGLRPEPLALPEPKQSA
                     IRFL"
     gene            complement(20238..20495)
                     /locus_tag="VVO74_001471"
     CDS             complement(20238..20495)
                     /locus_tag="VVO74_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU5695482.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCE
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            complement(20508..21221)
                     /locus_tag="VVO74_001472"
     CDS             complement(20508..21221)
                     /locus_tag="VVO74_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HEU5695483.1"
                     /translation="MNEIFNFHGQEVRTLTIDDEPWFVGKDVADILGYAKPLDAISRH
                     VDEDDSVKYGLTDNLGRTQNTIIINESGLYSLILSSKLPQAKEFKRWVTSEVLPAIRK
                     QGGFIREDLDEDAFIALFTGQKKLREQQTSMLEDIDYLKSEQPIHPSYAQSLLKKRKA
                     RVVACLGGIDSPAYADKIFAQSVFRQAEIDFKDHFNISRYDLLPKKHADAALAYWMTW
                     EPSTNTKMKIMKLNSFDEG"
     gene            21276..21953
                     /locus_tag="VVO74_001473"
     CDS             21276..21953
                     /locus_tag="VVO74_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002878731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEU5695484.1"
                     /translation="MYVPIKPTGDFSTNFTLSDSCKICKNITCPTVVNETTQSIDNDH
                     YRFCATRYCQQCNHYFVDEIEVTITVDSFANIDYQYDILDVKPELPSDIPISKELAKL
                     SPIGKEIYTQALKAEQEKLDHIAGIGFRKSLEFFVKDFVISFELENKDKVAKMPLKQV
                     IDNYIDNKTLKTFATATVYIGNDETHYTKKHSDKDLQDLKKFLHGFLHYMEMQLNLLD
                     AYQLLDR"
     gene            complement(22078..22239)
                     /locus_tag="VVO74_001474"
     CDS             complement(22078..22239)
                     /locus_tag="VVO74_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695485.1"
                     /translation="MNELVWFYFTIIINIVIGFATYYASKRDRKKRIDEYKKIQDDEL
                     ERVRKKFDL"
     gene            complement(22249..22446)
                     /locus_tag="VVO74_001475"
     CDS             complement(22249..22446)
                     /locus_tag="VVO74_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695486.1"
                     /translation="MNNAAQKVTRIDKDAWEIATELANEYGVSICHIISESVRYCAEN
                     AEFKEMDVVVKRLVVGSKVLE"
     gene            complement(22463..22666)
                     /locus_tag="VVO74_001476"
     CDS             complement(22463..22666)
                     /locus_tag="VVO74_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU5695487.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQAELAKQVSVASSVISELLKYG
                     KGSDYVKEKVVDILGIENPWENS"
     gene            22721..23203
                     /locus_tag="VVO74_001477"
     CDS             22721..23203
                     /locus_tag="VVO74_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695488.1"
                     /translation="MKSSFFHYLKEIILYGVLVPILTVIVGFHLFTTFYPISDSLLTD
                     FLKAFTEQRILAIVFVLILCFIFFGSIYYCISCGRNRKLIPDKVYTQITTYISSVGLG
                     TAVIAVATLTLTELQFSILTGWIAFIALLLPLLKFKVQYSTYQSSDNVAQKTTENKAN
                     "
     gene            23509..23874
                     /locus_tag="VVO74_001478"
     CDS             23509..23874
                     /locus_tag="VVO74_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5695489.1"
                     /translation="MFSLFEKIKELCQNRGISINSLEETLGYSRNTIYSMKNKKPNAE
                     RLQEIADYFNVSTDYLLGRTDNPAIAGDSKEYTWQGKTLNVEEMASNVMMFGGRELTD
                     EKKKIIQSIIEGYLKEAGD"
     gene            23887..24270
                     /locus_tag="VVO74_001479"
     CDS             23887..24270
                     /locus_tag="VVO74_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEU5695490.1"
                     /translation="MTEKEIISHFQVRIVDFDGELIPDELGFYEKETNTAFLSNKLSK
                     KERVKVLLHELGHKDHTRSEYQNARLRCENEADRNMIHHLVKDALESLDDPTEFDYLK
                     FMSYYNLKTVTNEVMVKEEYLALVN"
     gene            24308..25120
                     /locus_tag="VVO74_001480"
     CDS             24308..25120
                     /locus_tag="VVO74_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEU5695491.1"
                     /translation="MQKTVEKILFRVAGVTKYKKAVKEACNMIAEDNGIPEYSKYYGD
                     LSAKEIREEVEEYGLKVFKYRDLDIFNIELIPETDNKYDPNAIKVLIFDNHIGYVPAT
                     VSKSIRKYFDDERYHFLIECEIKGGPYKEWDDYEEKVVINNDLDVGFEIYLTIVDSSQ
                     KEVIQSESSEIIDDNIFNKEVTKTESIETKTTEAEHIEQNIVSDSFADIVNEINLSET
                     SPKKKLPANKIIFSALYLFLVFFGVVGIPIAPFLAVPLTAWSLYKLYKLFRK"
     gene            25294..26442
                     /locus_tag="VVO74_001481"
     CDS             25294..26442
                     /locus_tag="VVO74_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU5695492.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGVNTNLTLDQYWDIYSKKRLSTGRWNDTSYYLNDNLYK
                     NHIKTKFGSIQLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
     gene            complement(26684..27970)
                     /locus_tag="VVO74_001482"
     CDS             complement(26684..27970)
                     /locus_tag="VVO74_001482"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU5695493.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(28201..28437)
                     /locus_tag="VVO74_001483"
     CDS             complement(28201..28437)
                     /locus_tag="VVO74_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEU5695494.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            28702..29499
                     /locus_tag="VVO74_001484"
                     /pseudo
     CDS             28702..29499
                     /locus_tag="VVO74_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(29534..29743)
                     /locus_tag="VVO74_001485"
                     /pseudo
     CDS             complement(29534..29743)
                     /locus_tag="VVO74_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(29909..29982)
                     /locus_tag="VVO74_001486"
     tRNA            complement(29909..29982)
                     /locus_tag="VVO74_001486"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(29946..29948),aa:Asn,seq:gtt)
BASE COUNT         8773 a         6451 c         4897 g         9864 t
ORIGIN      
        1 agccgtctga gcgctcgtag tctgcgactt aaacgcttca agtctagcaa cagaatccag
       61 ctcaatccgc ttggcttcct gagcaagaga gctacttgcg ccagccagtt catttttagt
      121 ccggctaagt gcttcagctt gcttggcaat ctcagcttca acctgtgctt gcttcggtcg
      181 aatatcattc acgatagtcc gtttcagagc gtccaagtca cctgacagag ccgtttgtgc
      241 gctcgtagtc tgcgacttaa acgcttcaag tctagcaaca gaatccagcc caatccgctt
      301 ggcttcctga gcaagagagc tacttgcgcc agcttgtctc aaagcttcct cagccttgcg
      361 cttagtttct ttcaatggcc cgttgtcaaa gctattaaag cgctgattga tagtgtcaga
      421 cagttctcgc ttgacttctt ccgccttggc cttggcaagt tcaatatcgt cagaaatttc
      481 ctgtctaagc aatccagcct tatgatcaaa gtctaagtca gcattttgaa gagccttttc
      541 aagggcgatt tcttgtgcag attctgtcac tccaagaatt gcatcggctg cgctagatag
      601 gccaccagaa gctctagaac caccaatacc tgccttatca tcgaaagtca gagagaggta
      661 ttcttctttt aaggcatcga actcataagc aatagctttc ttgaatgcat cgacattatg
      721 tttccagctc ttgagattga ccgtgtcgcc catatggacc acttgcccat caagttcata
      781 agcttcaatc ttgatagcat cagagacctt gtcaattccc tcatttgaga acttagactg
      841 tgcccacttc tgcaactctt caacagtttt agcattgttg ttctcatact ctttttcatt
      901 gatataaggg tatgagttga taagaggact atcaacagtc actctgatag tcgtttcttt
      961 ttcagcacct tcaggtttaa aagtcgactt tgcgtgaatt cttgtgacaa cattctgact
     1021 gttttttgtg cgttggtagt tcttcagatt tttgtgcgtt gtaataacaa caccacgatt
     1081 ctccccacga ctcttcttga cagttatcgc aaagttatca cgaaccagct cgccttccca
     1141 tgtaccaaca atgctgtgct taccgtccag caatatagag tatagggttt ctgtttcagt
     1201 cgtattgaag gtcctacggt cctggatatc actgttgaat gagaagtctc caagagccgt
     1261 tttggtgttt tgtaccatgc gagaaagagc catgccacaa ctctgactag tcacacttac
     1321 tggtgtgata gaacgttgca tcacatcgtc tgaaatgtga taggctgtga tttccagatg
     1381 atcattgtat tcaacaggtt tcttaatgcg aaatagctgc gcaccaagaa caggagtcgg
     1441 cgcttttatc aacatatctt cttggatgag ctgataaata ccagagtcgg aaatgggata
     1501 tttcacagtt aaggtgaaat caccattcat gatctcttta acaatcgccg aagtcgcttc
     1561 atgaagtggc tccccgttcc atcgaacagt tcttacatct ttattaagta gataaagcaa
     1621 ttatgcccac ccccaaaccg tttcgatttc aatcgattga atacctgggc ctaaaacaac
     1681 cccaatattc ttaactttcg ctggatcaac tgtaataaaa tcccctgacc atttgactgg
     1741 cttccctgtt gtcgttttaa agctaggatt gtcaggatta ttaaccatca caagcgattc
     1801 tgagagtttt tcaagcctaa tgacctgacc agcgattgta aatgaagtct caacagcgct
     1861 ctgaccaacg attgtgattt taggaaaagc aagagcagaa ccttgaacgg tcaaggttcc
     1921 acttcttgtc aatctctgtg tatcggagcc tttaaagtat tttgtaggat ggcaagtgaa
     1981 ttttacatcc accgtccatg caccaaaatc atctttaata attttgaaat catccacttt
     2041 atagcaccaa tatttcacgc ttggctcttg ttcattctct aaccaaaatt tttcacgatt
     2101 taacagagaa gaaaaacggt ataagtcttc atccgttggg ttaatcaagc taatgtggta
     2161 gcttttttca atcaacctac gatgcctatt tgattgaaca attgcaccac taatcccatc
     2221 atgttctaaa agactagttt ttgaggagga tacgatgatt tgtggtcgtg tttcaaccag
     2281 aatctcacat ttaaatgatg atgttttcac tccatcaatg gttaactcat taatttttgt
     2341 catgcgaaac ctcctctcaa attagttttt ctttgtagtt cttcagcaat acgtgttccg
     2401 actacgtcag ctagtctatt caaatccgct tcttctcgga tggtcactcc tgagaagttg
     2461 acattgatgc tattcgatgt attcatcgta ttagcaatgc tttgtccaat tgcaccaaga
     2521 gttgacttat tgagtggaag gattgcttct gcaccagctt ctccaccaac cattgctcta
     2581 tttccattca ttccaaataa agttggtttg gtcatgatac cacccttcgc ataccactca
     2641 ataccgatgc ttggaacgcc ctgacttaac cagtctaatg gattggctga accacttaca
     2701 tagaagtgtg gtaatggaat gtgcggccaa ctgatattga aattaaatag attcttaata
     2761 gcttggatag cgttagatac tgcattttta gcaccatcaa tagcatttga aatagttgat
     2821 ttgatagagt tccaaatatt gctagcagtg gataagatac cattaaaaat tcctgaaatc
     2881 gtgctactca aattattaaa caaatttgac ccggttgaga ccaggccaga ccataaattg
     2941 gaaagggtag aagtaaaact tgaccacagt gactgagctc ctgaaatcaa acttgagaaa
     3001 atattggaca aggtgctagt aaagctagac cacaaagact gtcccgttga gactactgaa
     3061 gaccaaattt cagaaagcca agcagtgaaa cttgaccacg ctgtagtagc agtcgtaaca
     3121 atattagtcc acaattcaga aagccaagcg gcgcaagcat cccacgtcga ctgaagccat
     3181 tcagatatgg tcccccagtt catgatggcc tgaatgatga gtgtaatagc ggcaatagca
     3241 gcaactattg ccgctacgac aattccgaca ggcgcaccta ttgcacctat agcaatgact
     3301 agcggtgcta ttgcaccaag cagtagcatt acagcagttg taacgaggcc aagaatcacg
     3361 atagtctgtt gatcagtttc atttaagctg gtaaaccaat tgacagcaga ttcaagcatg
     3421 cccatcaaag gttctaaagc tggtataaca gtctcaagta gtgtaccacc tatctcggca
     3481 agcccttctt ttgctttgtt ggaataggtt gttaggtcat caaatggatc ttttgtctca
     3541 gcaaatgttg ttgctacagt tcctgatgag ttttgtgctg cttcagctaa atcattaaaa
     3601 ctaaatgccc cacgttggat agcatctacc attttaggag cggctctatt tccgaaaact
     3661 tcagaagcaa ttcttattgc ttctgtctta ctagtagcat tctgaattgc attgacagtc
     3721 tcgttcaacc cctcagtcaa tgtctttccg tctttagcat agtttactgt agcctttgaa
     3781 agtgaagcta aagctgcaga agagtcaatc ccactttttt caaatctacc aattaatgtc
     3841 gccccctctt taaaagataa tcctagcatc ttaatctgtg gagctccatc aattgctttt
     3901 tgaaagatgg agtcataaga ttgaccagta tcctggccga cctttgttac tgagtccaat
     3961 actctcgcta gatcctcatt agataaaccg taagcatcaa ttgctttctt ggcatttatt
     4021 gcggaatttg aaatatcttc tccagttatt ttcgaatatt tcaataggta ctctgctgca
     4081 gattgcaaag tatcaccagt aagtccaaat tgtgtattta actcaccaac tgcgtcagca
     4141 gattcttgaa atgtagccga tggtaaggat gtagcgattc cttttgcaat ttcctgaagt
     4201 cctaacaagg cttcgccagt aagtccagtc ttcgtcgtaa cagtatccat cgcttcgtcg
     4261 atttcagacc atgcatctac tgttttttta ccagcatcaa ccattttttg acctagttgt
     4321 cctgcctttt cagcaatgtt catcattaca tcggctttta agtatcctgt agcttccttg
     4381 atgtttcctg ttgctgaacg gctcgaatcc cctagattcc ccatggcttt atctatcttt
     4441 aacacctcga cttctgcttg cccaatttca ttttgaagtt gtcgccattc ctctgttccg
     4501 attttttcct ttcctaattc ctcttgtttc cgtttcaact cctggacctt atccttggct
     4561 aatgaagatt gtttacctaa taacttcatt ttttcttcgg acaactctac atttttagga
     4621 tctaattcaa gcttctggtt gacgatatca agttcttttg caacattgtt gatttctttg
     4681 ttgagattta aaatagactt tggatttcct acatcttcga tatgtttttt ggttgaattc
     4741 attgtctggt caacaacctt catctgtgat tcaactttag aaatttcaag ttgaagctta
     4801 ttccactgtg ctgacccaac ttcagattct cccagttcct tttgttgctt tttgagttca
     4861 gcaattttca tagcaccaac acgagcttgt tcttgtaagt tgagcaactt acgattcagc
     4921 aagtcgacat tgtctggatc catcttcaat tgtctattga tgttgttgaa atcttttttc
     4981 agactagata aagcattatt gatacctttt acagatctgt caaattcaac agtattagca
     5041 ccaaatttga catataagcc ttcaaatgtt tcagtcatag atttcctcct ttcagtttta
     5101 gtcagacatt acatttagta attctgcgtt tgataaagtt ttcttctcat tttcattgat
     5161 actcatctga tgtagtgttc ccatcagata attaaagtgt tgactttctg cccaaaaaac
     5221 atccatccga ttttcaaaaa caaccttata aattttttca gaagttatga cttctgttga
     5281 ggcttttttc tatcttgagg aacctttgct ctacttcggt taaattcata aaagaggtct
     5341 gaaaaaaaac caatatcaat caaatcacca aaccaaggag caagagaggc tgtttcagca
     5401 gtcagctcat tctgtaccaa gcgaccattc tcaacctcac cgtacagaca agggatgact
     5461 tcagttagga agttcatgaa atctggctcc ataagtaatg gcattagttt gaccttttct
     5521 tcatcagtta aagcagataa acgaccattt acaccagttg caagagcaag ctgtgtgtaa
     5581 gctgtgagtg ctttttggtt gtcatcaaag aagttgcgac ctgtccgctg ttcatacatc
     5641 ttgatagctg gtaaagagta aagaaagcgc actgtttcag tgcgctctct ttcttcacca
     5701 taactatcaa acgctgtgaa tgatagttct tttttaatca ttttatcctc ctggcacgat
     5761 ggctgttgtt cctaaagctt cattgataaa atcaatcaat ttcattgggg tacttgaagc
     5821 gaacaattta tcaaatttag cacggacaac acccttgtct gtatcacgcc atacaatttc
     5881 tgaaacaggt tttttatctg aatctagaat aaaattgttg ggtgacgcag tacatggaat
     5941 ttcaatttct tttggtgtag cagaactttc atctgttgta gtgctgcctt ttggagctga
     6001 tgcttttaca ttggtccaga tgtggaactc ttcaacctca gaaccaaact cgtctgtaac
     6061 cgtttcagca tatccccaaa taaaattcgc attcacacca gtatcgatga gcgctggagg
     6121 agttgaagtt gtcagctttt tacccaagtg atcaatcatg aattgtttag gaatttgata
     6181 agtcgtgatg gatccctcag ttgatttctt accttgaaga cggacgtgct ccacgttatc
     6241 tgcgtagtat gcatttgatt cttgtgaagt ttcaaaagat gtttttcgca atcctgtaaa
     6301 tggatacggt ttttttaaat cgagtgtgcc agattctgtt ttggaaatct tggcaaagaa
     6361 tcccgtggta ttaccatgag ttacctctcg tgtgtcatat ttataagtca ttgtgactcc
     6421 ttccttaatt tggtctgatt tttattgatt tcatattatt gagaaagatt tctttatttt
     6481 tgaggtatgc tggtctgatg tgttcttgag gtgctacaaa tccaccattt tttgttgcat
     6541 ggccattttc taacaagtga gcaagcgact tctctttccc attgttatat actacagcga
     6601 tatcttcaat ggtctcgtga gtccatcctt tttcatatac tccgtttctt ctaggacttc
     6661 cgtctctaat gtctccagcg gtgctttttc ctgctttttc tatgatttct aaaacttgat
     6721 tctggatatc gatttttaat gttttcacat taacgctacc acttcccact tgtgaatacc
     6781 tcgattctgt aggttgtaag taagtaatct gtatcaggct gttttagatt caactgacta
     6841 ggttcacaca taaaattaga caacatcaat tcctcaatgc tgtctaattt cttcttgtga
     6901 tagtgactga tttgaatagt cacttttctc atgtgtactg tgtcatcagc agtaatacta
     6961 ctacccggag ttaaacgata gtaaagaata acgttgtcag gagaggactt ttcctcacgt
     7021 tccatataga acacttttga ttttaaagtg tttttttcta ggatttcttg aatttcttgc
     7081 ctggtgaaga acttcttagc cattatttca attctcctaa ttcaattatc gtgtagtggt
     7141 catcatcaga ttcagttcca acatttacct tgtactcttt ccctttgtac ttcacgtagt
     7201 ctaaggaatc tgtcacatag ttagaacgta tccgaaatct tgctgtcaaa acttgaccat
     7261 ctgccaaagc tttatcaagt ctacgttggt agatcttctc tttttcagct ttgactttct
     7321 tttctacaac ttgtttttca aaaacacctt tttcgacctc tgtacgctca tcgtaacaaa
     7381 ggatgattga tactctagat gatttcatga tttaactccg taaatagctt ttaattgata
     7441 aagaatattt gtcaattctt catcaatcca gctccttgtt gttgaatttc ctgtcatcaa
     7501 ggatttatca aatctctgaa cacatctcaa atgtaaccaa tctaaaattg tttctttatc
     7561 atcctcttca atctcattcc attctgtcaa ttcgctttct ttatcgatgc gattgatagg
     7621 aatgttgttt ctcgttagat atgaaatccc actatttatg tagcttaaaa attgagtgtc
     7681 aaagatttct tcttcgacat caacttcaac catttcttta atttggttaa ggattgtcat
     7741 tttagactcc cctttctatt taaaatcaac cttttgtgaa tttcacagct gatttgtact
     7801 gaccaagtcg gccaccaagc acgctagcaa gttcgatatg acggcgattc atcgttacat
     7861 cataatcttc aaagcgatca gcagaaacat catcaccaat catcttataa gccttgtcag
     7921 caaatgcgat aattgggtta gtcgcatctt ccatccagtc atagacatat acttggtaac
     7981 cagcaatgac attccctgtt tgtgaaattg gtgcgaatgg ttgtgggtca atgtagcgtt
     8041 tttcgccatc cttaaccatt ttaagtttac gagcaatggt ttttgaagtt accaaaattg
     8101 gagttgtatt tgcagcaagt ttatcaatcc ctttgacgag gttttctaaa acagtactgt
     8161 caaattcccc gtcaacactg atttcttgtg tatcaaatag ttgagcaagt gtttcttctg
     8221 cgatagattt aatttcagtg attttgtcat catcatcact atttttacca tctccgataa
     8281 caacagcacg ttcaactgca cggatgaagc cttgtgctag ttcattcatc acatagttga
     8341 agtaagcacc tgttgtatcc ttcttcaagt cagcatactc aaaactgtac ttgatgtaga
     8401 cagctgcaga gttgattgta taatcgataa atacaaaaga ttcatctttc tttgttttgc
     8461 cattttgatg gcctttagct tttgcttgtt gcgtttgaag cgcaacacgt actgcataac
     8521 gaggatcttt ggttacatgg ttcaggatac catcgtaatc attaaatgca ttttggattg
     8581 caatcaatac tggttcaggt aagattttgt taacatcagt tacacctttt tcaaccagat
     8641 ttgcttccca cgctttgcgg gcactgtttg agcttccttc attatccata aggattcgag
     8701 cgaaatcaag tgcagcttct tttgttttta agtattccat ttgtatcttg cctttctgta
     8761 cttccttgat agatttagca gctttattga gattgtcttg tttttcttca atctcaacat
     8821 ctaacttaga aattgtgttc ttgagttcat ctgctttgga taccaatcct tctgcatccg
     8881 atttcaactg tgcaagttct tcttctccaa tagttgctga ctccaatttc tcttcgattg
     8941 aagctttttt aaatttgatc tcagataact catctgcatg tttttgtcgt tcttccatca
     9001 attcgactag tgttttcatt ttttctcctt ttttaaatcg ttgcaagttt actcatgata
     9061 tcttgcttca tgttcgcctg agcgattcgc ttgtcaacca cagacatatc aaatccctta
     9121 atattatcaa tggttgcttg aggattggct ggcacggtca cgacagatat ttcaaagatt
     9181 tcaacttctt taaaaatcca tccaccgtaa ggttgcttag cgtcaactgg ctcataatca
     9241 ttaataaaaa atccaatgct cagactatcc agtgccccca tcttcatgag gtcataggtt
     9301 ttcttagctt ctggatcgct tagattgaat gttgaccgtg ttcgcagacc tttttcatct
     9361 accgacagct catgcttacc gatgacgcga ttgcggtcgt gatttaagca catagggacg
     9421 acggccttag ttttcagggt attgtcaaaa caccccttgg ccatcacatc accatctctg
     9481 tcggtattgc cataggtgga ggcataagcc tcaaagtgaa agtcagctga ctcttcctca
     9541 actgacttga cgacaaaggt ttttaatttt tccatatcct acctcctttc ttaaaatttc
     9601 tgccaaccgc ccaccctatt tttaattact ttcgctcggc tcgatacgga ctgcatttag
     9661 attggtttcg aatacttctc caccttcata tcctggaagc cctagatagg tttcacggaa
     9721 ttcatttgaa ttcatcaaac ctgcgtattt agatttaaat ccaccttcta ctagatcctt
     9781 gaatgaaatc atgtcagcca tatcaaagaa gaccaagagc ttgtttcctt gtgtccttgc
     9841 cgtcttcgtg aaatattttc tattaatttc ttcagagaat acacgttgat ataatttcat
     9901 gacgctagaa tagtaagctc tatattgttc ttctgtgtag tcacaagtaa acaatttttc
     9961 attaattcca tgagcatgat aaagttgaga tttcagaaac tccatttctt ctttagaagc
    10021 ggttgagtaa tctttgttta attccataaa ctcttcacct tgctcgagat aggcaatgcc
    10081 accaatttca gcaagttcca tcatgctatc aactctactc ttagcttgtt tcttcaaatg
    10141 ttcatctgct gctttagttg gtagttttaa gaatcctctc aactttgaat tccctctgcc
    10201 taacttctcg gttaacgcat caaggttgat atcaattaat tctgtgattt ggtttagttg
    10261 acttgtcacg tttaatttag gattttcaaa aacccagaca tcgctaagag gtagctcaat
    10321 ctctacatca tcaatcatga tttcaactct ctctgcagtc catgatatgg ttttctttgc
    10381 aaaccaaatt tcaatcagtc gaccattttc ccaacgtgga acaacgactg caacaccatc
    10441 tttcagcata gctcttgtta catttgccca aaatacaact ggtatttcaa gaggatttgg
    10501 agagaaagat aaaacatttg caagatcact attttcaaac cactccatct tatcaactcc
    10561 cgtcggattt cgagtgattc tcacatgctt aaatcgaact tgtgcagtat ctgttgaaat
    10621 cttattgtag atattgtcta agtaaatcga atttcttctc caataattca aatttctttg
    10681 taaataggtc cttgtggatt ttctattgct tggtctgaaa atcctagcaa aaacctctct
    10741 taaattattt atatatttgt tcattcttca cctcaatcaa agtaataact caagtcttcc
    10801 ttgaaatttt cgtagcagat aaaagcatct aactgactag caaatacgtc aatcttttct
    10861 tttgcttttt ctttatttgg aaatacattg ttattcgcat ctatcttgac acgaacattt
    10921 gcgtggttcc aagttgccac aggatcgtca aagatgattt tccccatctt agctttttct
    10981 ttatacactt ttaaaggatt ggataagctc ttgaccgttt gtggaatgtc gtgacatata
    11041 tctccgtagt agtcattaat taagcggata agctcttttg cattccagcg gtcatatccg
    11101 actgcaactg gtaagattct attctcactc ataaactgcc ttaattcttc aaagatataa
    11161 gcttgatcat tgtagtccaa ctcatgaaca tgaagctgtc cactaagctc ccactcagcg
    11221 tatttgtccc tcagttcttt cggaagtcct tcaatcgtat gacgtggcat gaatttcttg
    11281 ttcaaatact gacgctcttc gccacgcacg accataaatg agaccgaaca aatgtcattg
    11341 acatccgaca agtcaacacc aagcacacag cgagcactcc tctcctcatt tccgacaaac
    11401 aaactcttat caaacttatc taaccaaccc ttacactctt cattactgaa gtaagcaaga
    11461 tagttattaa cagggagatt aaatgtttta gccatcagct cagcctgttg tgctggatca
    11521 ttcttgctca tttcaatatc cttggcaatc gtctccttct cagtcgttat accgagtaaa
    11581 ggcatagctt tctgccacat atctggattg tgaatttcag aaacatcatc cagctgataa
    11641 atccaaggca tgaccgaatg attgacaatc ttttcatcaa gaatatctac ccagatgttg
    11701 taatacttat caaaaagctt gtcccgtttc gtcccattgg tggagatgta ccaggttatc
    11761 caattttttc gcttgcgact cgaaccatca ttcacaacct tgatgaagtc atcatcataa
    11821 gtgtgcactt catcaaaaat attgtagtga gcattagtac catcaagact ttcatagtcg
    11881 gaagtcttga ttgacataag actattagtt gtctcgtaca agataccttg tttagttgac
    11941 cgtagtatgt cagcctcacg catatagtgt agcaagctct cttcgttcga cagcatagct
    12001 ctagaagcat taaacagata tccagcttgt tcacgactgt aagctagaag ctgaatatca
    12061 gcaccccact caccgtcaat aatctgacca acctcaccaa tggcagaacc aagggttgtt
    12121 tttcctgtac cacgaggtac aataataggc acctcatgaa tgagacgcct ttcttcaaaa
    12181 tctttatatt cttcaagtgt atcgggatct gtttttgtaa cttcaactgt atgataaaaa
    12241 ccccacgttg tttctagcca gaccttctga ggcaaagcca agtgtaactt tccagcaaga
    12301 cctttagtgt tgctgcactc ttcctcaatg aactcaatcc gtttgtcaac ttcttcttgt
    12361 ttaaagatgt attgttcctt gtacctctct actcgtttaa tcgacttcat cgtaagttca
    12421 caaacacgaa tcttccctga gtagaccagc tgagcatatt tatcaaaata tctcatctca
    12481 accatatcga gccaacttct cctgaatcat ttctttgagg ctatcaccct gtggactttg
    12541 cttttcaatc gttgacataa tctgcatgtt tagcttttga tacttttcca ttccatcaag
    12601 taaatactta tcaggtagct caccgtcatt gatgacttta ttgatttcca attggaagtt
    12661 ttcaatcact ttttgattat gattgtattg agttttaaga tttttcaaac ctactgaatc
    12721 attgtcattg atttcaagca ttttttcttt tggaattaac ttgaaagtct tacgagatag
    12781 ttcaacacgt tcttctcttg tatacttctg ccgttgattt gccagctttt ctaactcttt
    12841 gaattgactt tttgtgatat tcgaccgagt ttcttcaaat atgcctagct tttttcgata
    12901 cctggtgagg gtagcacgac ttattcctag cttttctaaa acttcattga ttttcaaaat
    12961 catactcctt tcttgtatca attttcgtca tttttggggg agaggtatat aagaggattg
    13021 acaccgttat tattttgggt gtgtgaaaat tttaaatagg ggggatctga taaaaataaa
    13081 aaattcaaaa aataaaaaat caaaataaat taatattccg attttctaaa tttaaattta
    13141 ttttactttg aaatgttttt gtattatgac actcgagaca aagtaattgc agattatctt
    13201 cgttgagagt aatagactca tcttgataat tagtttcatc aatctctata atatggtcaa
    13261 caatgctctt gccatgaatt aaacgtccac acatgtcaca gcgcatacgc tttatacttc
    13321 tgattctatt tctcaaagtt ctccaaggtt tcgagttgta gaatttaatc tgccaagttc
    13381 taaaccagtc agagtgttta ggattcttga atgtcatagc ttgaatgatt caactcggat
    13441 ttctcttgtg tatctgttca tgaacgaaat catcttatac attggcttgt cccatgcata
    13501 aattattgat gtgtcaacta gaatctcact agtcaacgag tacggatacc tttttggtct
    13561 catgcttacc tccaacaaaa agagaacaga tctagacttg ctctccgaat ttttcgcatg
    13621 atacaaatat atcagattca ttttgtcaat gctatatctt tttttgacaa gatttatttt
    13681 tgagttttga atttatgtaa aatatctctg ttgaattagt tatatcttat attttatcca
    13741 attttgtttc atactaaaaa actagcacgg acaacgcttc aggccctctt caaaatataa
    13801 actagaaacc tcctcgttat ggatagttga aaaaatcaaa aaaatattag aggctaaaat
    13861 tactcatctt agtatcaagt tcatcttgcc ttacacaaat ataaattagt gtaactgctg
    13921 gacttgaatg attgaataat gacatcaagt ctgcaacgtt cttgtacttc ttatagtaat
    13981 gatagccaaa tgtttttcgc atcgtgtgag ttccgacatt atcgattcct aagtcttcag
    14041 cagctctttt aagaaaccag tataccgtct tatagctgag cgccttattc tttccgacac
    14101 gactctgaaa tagatactca tgtaattctt tatctttgac aaattccctc aattcattct
    14161 tgagtggcct tgtcatttta atgctcttgt atttccctgt tttctgttcc ctaactttaa
    14221 tatgccaacc ttgaacatct ttaaccttta gtttgagaat atctccgaca cgaaaacctg
    14281 tattgattcc caaaagaaat aacatgtaat acttttcatt ccaagatgat agatagtcct
    14341 tcatggcttg gatatcatcc ttatctcgta acggttcaac aatattcata gttttactcc
    14401 tttcacaaaa aaataaagca ctaagatttt ctcagtgctt tggatagtat caatctatca
    14461 tattcttttt gtcaatgcta tacttttttt tgacaagtta catgaacaat aactttgcaa
    14521 gtgtatcaag aatgatttca cgtcttctgt aaatctgctt actgtgcctg tatagatacc
    14581 cagtgtcacc attctccatt ttatgccaaa cttgaatcca atcgtaccta gtgtgttctc
    14641 cccatttcaa atgaaagatt tttttatcat caggttcaag tacatcgagt agctttgaaa
    14701 ttgctgtttg aaagttttcc agtcttaaaa ccatcggatc gcttgcataa gcaactgcta
    14761 ggttctcaga cctatttacg aacgtgccac ttccgcttgc accagtatca tcaataccag
    14821 gaacagtgag atgtttcact tcgtacaatc gttctaattc atgtcttctt tgaccaatca
    14881 atttgtcaat ctgtaagtat ttatcattga gttcaaactc gagataatct cttcgtgctg
    14941 ttattaggtt ctttttgccc aaaccttacc tcccatatat cttttagttt tgacccatag
    15001 gaaaaactct tctggtgcct ctttttctag aatgtccaat aatgaacact cgttcccgat
    15061 tttgggggac tccgaaattc ttgctgttaa gcacttgcca ttccacgttg taccccagtt
    15121 catccaaggt tgagataatg gtctcgaatg taactccatt ttcgtgattg agcaatcctt
    15181 taacattctc aaggaataga tatttaggtc tgagaataga tgcgaaccta gcaatttcaa
    15241 agaacaaagt tcctcgtgta tcttcaaaac ctcgtctgtt tcctgcaatt gagaaagctt
    15301 ggcacggaaa tcctccacag ataatgtcca cacttccgat tcctcgaata gattcatctg
    15361 atactgctgt gatgtcatgt aattctattt ctcctttcgt attgtgtatc gctttatagc
    15421 tttctctagc aaacttgtca atttcacaaa agccaataca tttatggccg gcagactcca
    15481 ttcctaaacg aaaaccgcca attcctgcga ataaatccaa gaatttcaca acatcacctc
    15541 atccccgact ttcaccttgt catacacgtc cttcataacc acaagcaccc cttagtcacg
    15601 atctgtgacc tccttttcta cagtaattgt aaattcacgg tcatttatgt ttaaaggtag
    15661 aactacccct gtttttgaat cgtcttttag caaatccaat acaatttcta aaacttgctt
    15721 acctaaaatc aattgtatct ctaaaatatt ttgctcatct tccatcactc cacctcctca
    15781 aaataactat gaaatttact taaattgaca atagcgacct cttcaacaga atgctttccg
    15841 atgtcaaagt ctggatcatt cttcccaaac tctttttcta tagctttttc agccagaaaa
    15901 ggcaaatcga atatacttgc cccatttctt aaagcgagcg cttgaccgta tttgttcact
    15961 attcgatacc ctatatcaaa cggtctgatt tcccttggga cttttatgca tttactttga
    16021 ttcttcattc cttcttcaag tgtttgtgtc atcactccac ctcctcaatc tcaatccctg
    16081 ggcaatcaaa cacccagccg aacccggctt cttcaagttc tttgcgggtg tgggctatta
    16141 tttgatgttc tggttcataa gctgaatgaa aaaaccatat atcttttcgg tttccagaaa
    16201 taaggtaatt agtaaaatgt acacctttca ccttcaccaa ataccgcttc tctttttcga
    16261 cctcgtagcc gaagttgtgc atgttgacga gggtttgaat aggattttct ctggtgttat
    16321 taatccaatt attaaactct ctattttctg attttttagc ctcatccctg aaagcaatcc
    16381 aatcccaaac attaaattca aaagaatcct tattctcttc ataccaatcc gccacaaatt
    16441 gctttacttt gactggtttt ggttcatcta gctgttctaa gtcttttaaa actagctgac
    16501 aaactacaat cgctgcaata tcaaatgaac tattctccag ctctttatat ttctcaatca
    16561 attcctgctt attcatctta gtttcctcta taaatcaaat aaactgcaat aactacctga
    16621 gacattcctg gcgaatagcc aacccaatca tcaaactcct tagattttgg caaccaatcc
    16681 ttagtagctc ccaaatcata gtctgtaggc ttttcatcag cgaagatgca ttccatcgct
    16741 cccataaacg tcataccatc ttctgccatt tcccaaaaat agtccgcccg gtctttcacc
    16801 gcttgtggta aatcttgctt gggaggttgc ggcttcccgt cttctaccgt ccagttgtat
    16861 acttcattaa ctttttgctt taactcttcc atcaccttcc aactcctcca ctttccgtct
    16921 caattcttta ttctttttcc tcagcaaatc gcgctccagc gctctaatcc gtctcttgcg
    16981 tgcatcgcac ggcttcgaat actcgattat cttctcttcg ttttgctcga tcgtgcgttt
    17041 cagtccgtca atctcagcct gtttatcgta cttcatcttc taaaaatctt tcaatagctt
    17101 ctctgtagga gacttccacc agaccgtcta agtcgttcag ggcttcaata tagtctggac
    17161 gaccttgccc gtactgctct ttcaaaaatt caacaaagag atgaatttcc tgataggtta
    17221 ctccaaccat gtttcttacc tcccactaaa aatgtaacgt tattgatcat ctttcttttc
    17281 ctttcttgct gcacgttccc cgactaaata gccgagaaat aaccacagaa tagccattcc
    17341 aaattcttta ataagttcaa tcattttttt ctcctcctga aaaagtcgct aaatagtaac
    17401 aatccttaga accgtagtca aatcgtgtcg tccgctgacc aatgtgcttc tgaaatcttg
    17461 gatgagtgat agccgagaaa gcccactgat gatcttccat ctgttcaatg agatcatcga
    17521 cattgtcaaa cgttccaagg taaaacttgc agtgcccgtt gtagacgaaa taaagctcta
    17581 acatcactcc acctcgacag ggtaaaagtt cccaaaggaa cctctcaatg ccttgctaac
    17641 ctgtaaggct gccgcccgag aaataaaccg catggctttc ttctcctcgg aacacgaaat
    17701 atccaagcca gtcacactga taattgcaga ccttagaaac ggcttatcct ctcttgtccc
    17761 atgctttaaa ataaacatca gccaccccta ttctaaaaat attgctttcg cttgtttgtc
    17821 aaatcattga aaaccatcaa atggtcttta tctacaccct tcattagtct ggacatgaaa
    17881 ggtctgccat atcttttttg aatatcggta gaaatcaaat ttgtggtaat gattgtgttt
    17941 gaacgcttat tcaagatatt gtagagaata gtaaatgacc attcgctatc tttttccatt
    18001 cctaaatcat ccaaaaccaa gaacttagca ctagcaattt tattgaccag aaactcttcc
    18061 tgactaaaat cagctttaat cttcatcagc aagtcagtta cgttaataaa aatagcaatc
    18121 tctttcgtgt actcagatag agccttaacc atagcaaaag ccaaatggct cttacctgtt
    18181 ccagcttctc cttgtaacac gatgttgttc ctagcaccct cagaccactc acgacaaatc
    18241 ctctttgcaa aagctagctt ttccgcttct ttttcggttg gtgtttcaaa attgtccaaa
    18301 gtagcatttt tcaaaatttc atcataaaga gagaactttt caagatagta tttcctctct
    18361 cgctcattct cagcattagc cagttcattc actctttcct gattttcttc atgaatccgc
    18421 tcagattcac acatgcgaca tacaacactc tcggtcctca atatctttat caaagggatg
    18481 ttatgctttt cgcagaactc ttcttgttgt tctgtattcc tacgataaga taaggcgatt
    18541 tcctcaaaca cattgtctac catactagcc gacctccgca ttcatgccag ctagccattt
    18601 cagacaagca ggcaaccact tgatgaattg gttggtctgc taaaagagtt ttcttctcgt
    18661 agcttaacgg ataatagtca atctcgaact gctcaattag ttctaaaatc cccattcgtc
    18721 ccttacctcc tgttccgatg ttttatcgtt ttgttgtctt gacttcttac cctctttata
    18781 tttacggtcg tcctcatcca cctgctcaat cgatgtgaag cctttctttt tccaactttc
    18841 aagaatggct attaggtaat tgaaactagg tttgtgtgat ccggaagttt tctcgactgc
    18901 acggttcaac atatcgaaac tcattccatc aagtcccaca taatcaagta actgttgatg
    18961 tgacttatca gttagatgga ttccgctatt tttcaaattt tcagaaaggc tggaactaat
    19021 catcacctta ttattattta tctctatatc tttatctaat tctttatcta gtgcgttacc
    19081 atgcgttact gtaacgttat ccataacgtt atcagtaacg ttactttcgt tgttctgtgc
    19141 aagtaatttc tgtttttgtc ggtgacgtgc tgctctattt cgattttgct cttttatttt
    19201 ttccatgccg tcaatgttct gatgtttctc ccaattgggt aacattatca ctccatcgat
    19261 tttttcaacc attccaaact tttcaaaaac ttcaagagcc atacgaactg tattcaacgg
    19321 acggtggaac gtttgtgcaa gcatttcatc ggtgtataca atgtttttag aaatggttag
    19381 tacgcctttt gtattcaatt tgcctgctag tgttataagt ttgatccaga ttacaataat
    19441 tgcatcacga tcaggcgagg catcaattag acacatcttt tcatcgtcaa aaatatccgt
    19501 tttgattttt atccacttga tttcagacat accgagcacc ccacttcctg cgattggcac
    19561 ggtacttcat ccgcatatcc tcatagatgt gcctgccttc cagctccatt ttttcaagct
    19621 taagtagacg attttcagac gatagaattc gatagtcttt ggctagcttg ttataatcgt
    19681 tcaagtattc cttgatcatg aacatggtat cattatcatt ttctagatgt aggttaaagt
    19741 ccgatgtttc ctcgtcagaa atcatttccc tgtttaattt ttctttggtt tcaagccatt
    19801 caatcaattc ttccatttcc tgacctcctc attacaaaaa tctgattgca gactgtttag
    19861 gttctggcaa agctaacggc tcaggacgca atccttgagg cggttcattg tcgtaggtaa
    19921 agcccttgaa cggacgacga atattcttgc ggatttcttg acgttcagct tctctaccac
    19981 gttcgtaagc atggttatag cctcgaataa tcatagacgc aaattcttgc tcttctcgtc
    20041 tttcttcttc cttgcgttgt tcctgcaatt tgatatgacg gcaagcccct gcaaatccaa
    20101 gcagtaaggc tccaaccccc atcaactggt ctaaaatcgg tggttcaaac atttttatct
    20161 ccttatcctc tttttgtgct ataatatagt caaataattt tgctaagacc ttgtccagaa
    20221 gccttttagt aaagttatta tatttgatta gagagccatt ctttgatggc tctttttgac
    20281 catttcttac caggtaattc ctttggaaat ccctttaagt aacgataatt atctgaaaat
    20341 gtggcatact taattcctag aaattcgcag gtagtgttca catccatcaa ctctggatag
    20401 tgatcactat ctttttctat ttcgactagc cttgtgattg tgtccttgat aatagattta
    20461 atccattcag atagtgaaag tagaacattg tccatcttct tcccctccta cccttcgtca
    20521 aatgagttca atttcatgat tttcatcttg gtattagtgc ttggctccca cgtcatccag
    20581 taagcaagag cggcatccgc atgcttcttg ggtagtaagt catagcgact gatattaaaa
    20641 tgatccttga aatcaatctc agcttgtcta aataccgact gagcgaaaat cttatcagca
    20701 taagcaggac tatcaatacc acctaagcaa gccacgacac gagctttgcg cttcttcagg
    20761 agcgactgag catagcttgg atgaatcggt tgctcgctct tgaggtagtc gatatcttcc
    20821 agcatgctag tctgttgctc ccgcaatttc ttctggccag taaaaagagc gataaaggca
    20881 tcctcgtcca agtcctcacg gataaaacca ccctgcttgc gaatagctgg caaaacctct
    20941 gatgtcaccc aacgcttgaa ctccttagct tgaggcaact tgcttgataa gataagagag
    21001 tagagaccag attcgttgat gatgatagtg ttttgtgttc gacctaaatt gtcggtgagt
    21061 ccgtatttca cggagtcatc ttcatcaacg tgccgagaaa ttgcgtccag tggtttagca
    21121 tatcctaaga tatctgcaac atctttccca acgaaccacg gctcgtcatc aattgtcaaa
    21181 gtacggactt cctgcccgtg aaaattaaaa atttcgttca taatattcct ttctaaattt
    21241 ggtataataa aaataaaaac aaggggtgaa taatcgtgta tgtacctata aagccaactg
    21301 gagatttctc aaccaatttc acacttagtg attcctgtaa aatctgtaaa aatattactt
    21361 gtccaacagt tgtgaacgaa acaactcaga gtatagataa cgatcactat cgattttgcg
    21421 caactcgcta ttgtcaacaa tgtaaccatt attttgttga tgaaatcgaa gttacaataa
    21481 ccgttgatag tttcgcaaat attgattatc aatacgatat attagatgta aagccagaac
    21541 ttcctagcga catcccaata tcaaaagaat tagcaaaact ctctcctata ggcaaagaga
    21601 tatatactca agcacttaaa gctgaacaag aaaaacttga tcatatagct ggtatcggtt
    21661 ttcgcaaatc cttagaattt ttcgtaaagg actttgttat ctcttttgaa ttagaaaata
    21721 aagataaagt tgctaaaatg ccactgaagc aagttattga taactatatt gataataaaa
    21781 ctttgaaaac atttgcgact gcaactgttt atataggtaa cgatgaaacc cactatacta
    21841 aaaaacatag tgataaggat cttcaagatt tgaaaaaatt ccttcatgga ttcttgcact
    21901 atatggaaat gcaacttaat cttttggatg cttatcagct tcttgatagg tgagcatagc
    21961 attctcgatt ttatccaact tctcagcaat atatgccacg gtcctcaata cttcattgag
    22021 ggctgttctt tctagttcgt tcataatgtt cctttctaag taaagacttc taaaaaatca
    22081 taaatcaaat ttttttctaa ctctttcaag ctcatcatct tgtattttct tatattcgtc
    22141 gatgcgcttt tttctatctc ttttgctagc gtagtatgtg gcaaaaccaa tgactatgtt
    22201 gataatgata gtgaaataaa accatactag ttcgttcatc ttcccctcct actccagcac
    22261 cttactgccg actaccaatc gtttaacgac aacgtccatc tccttaaatt cggcattctc
    22321 tgcacagtag cggacgctct cgctgatgat gtgacaaata gatacgccgt actcgttcgc
    22381 cagctccgta gcaatctccc aggcatcttt gtcaatccgt gttacttttt gcgctgcgtt
    22441 gttcatacta tttcctcatg ctctaactat tttcccaagg gttttcaata cccaaaatat
    22501 ctacgacttt ttctttcaca taatcacttc cttttccata cttcagcagt tctgaaataa
    22561 ctgatgatgc tacagatact tgttttgcca attcggcttg agtcatatcc agctcaatca
    22621 aacgagtttt gattttagcc ttgattatct ttagttcttt actcatattt ttcctttcta
    22681 aatttgatat aattaaaata aaaacgattg gaggagaata atgaaatctt cattttttca
    22741 ctatctaaag gaaatcatct tatatggtgt cctagttccg attttgacag ttatcgtagg
    22801 atttcacctt tttactacct tctatcctat ttctgattca ctgttaacag atttcttgaa
    22861 agcttttaca gaacaaagaa tccttgctat tgtattcgtt cttattcttt gctttatatt
    22921 tttcggttca atttattact gtatttcatg tggacgaaat agaaaattga tacctgataa
    22981 agtttataca caaatcacaa cttacatttc atctgtaggt ttagggactg cagtgatagc
    23041 tgtcgctacc ttgactctca cagaattaca gttttcaatc cttacaggtt ggattgcttt
    23101 tatcgctttg ttgttgccac ttctgaagtt taaagtccaa tacagcacct atcaaagtag
    23161 cgacaatgta gcacagaaaa ctaccgaaaa caaagccaat taagaaaggc tctaccattc
    23221 tcctctcccc ctttctttta aaaaattatc taaaaagtta gcgaattcct tgacaaaaaa
    23281 caatctatag tttagaattt aatcatagag aaaagaccta ctaaaagtaa ggttctacct
    23341 agaaaacgga cgccaatcag tttcattagg ctttattttt tagttgtctt gttcgctaac
    23401 tctttagctt acaaataata ttctaaacta tagattgcat tttgtcaaca tatttacaat
    23461 caaaagttta aatatttttt gtcatgcctt agaaaggttg ataaatcaat gttttcttta
    23521 ttcgaaaaaa taaaagaact ttgccaaaat cgtggaattt ctataaattc tcttgaagaa
    23581 acattaggat atagtagaaa tacaatctat agtatgaaaa acaaaaaacc aaatgctgaa
    23641 cgtcttcaag aaattgctga ctacttcaac gtgtccacag attatttact tggtcgcacg
    23701 gataatcctg ctattgctgg tgattcaaaa gagtacactt ggcaagggaa gaccctaaat
    23761 gttgaagaaa tggcatctaa tgtcatgatg tttggcggcc gagaattaac agatgaaaag
    23821 aagaaaatca tccagtctat cattgaaggt tatctcaaag aagctggtga ttagaggtac
    23881 tgcttagtga ccgaaaaaga aattataagt cattttcagg ttcgcattgt cgattttgac
    23941 ggtgagctaa tacctgatga acttggattt tacgaaaaag aaaccaacac agctttcttg
    24001 tctaacaaac tcagcaaaaa agagagagtt aaggtactat tgcatgaact cggacacaaa
    24061 gaccacacac gctcagagta ccagaacgct cgcctacgct gtgaaaacga agctgatagg
    24121 aatatgatcc atcatctcgt aaaagacgca ctagaaagct tagacgaccc cacagagttt
    24181 gattacctca aattcatgtc ttattacaat cttaaaactg tgactaatga agtcatggtc
    24241 aaggaagagt acttggcatt agtaaattaa aaattgcatt gaagatattt atatagaggg
    24301 gaaatatatg caaaagactg ttgaaaaaat attattcaga gtcgctggag tgacaaaata
    24361 taaaaaagca gtaaaagaag cttgcaatat gattgctgaa gacaatggga ttccagagta
    24421 ttcaaaatac tatggcgatt tatcagctaa ggaaatcagg gaagaagttg aagaatacgg
    24481 tctaaaagtt tttaaatatc gagatttaga tatttttaat attgaactca ttccagaaac
    24541 ggataataaa tatgatccca atgctataaa agttttgatt tttgataatc acataggata
    24601 cgtccctgca acagtctcta aatctattcg taaatatttt gatgatgaaa gatatcattt
    24661 cctaatagaa tgtgagataa aaggcggccc atacaaagaa tgggacgatt atgaagaaaa
    24721 agttgtcata aataatgatt tggatgttgg ttttgaaatt taccttacca ttgttgattc
    24781 ttcacaaaaa gaagtaattc agagcgaatc atctgagata attgatgata acattttcaa
    24841 taaagaagtt acgaaaactg aatctattga aactaaaaca actgaagctg aacatattga
    24901 acaaaatatt gttagtgata gtttcgctga tatagtaaac gagattaatc tttcagaaac
    24961 atctcctaag aaaaaacttc ctgccaataa aatcatattt tcagcactgt atcttttctt
    25021 agtctttttt ggagttgttg gtattccaat cgctccattc cttgcagtcc ctttgacagc
    25081 ttggagtttg tataaactat acaaactatt cagaaaataa aaaaaagccc cacaatcgcc
    25141 ctcgccaaag tttgattgtg aagcttacct tgtataaaaa tcagccatta aaaaggcctc
    25201 ttttctatac cctattttac accatgaaag gggtgatgtc aatattctca atgtttagac
    25261 cttgtccaga agcctgtaaa caaggagaat acaatgaaat ataataaaac aaaataccca
    25321 aatatctatt actatgagac tgctaaaggc aagcgttact atgtcagacg ttcttttttc
    25381 ttccgaggta aaaaaagaga aaaaagtaaa agtggtttca caactctccc tcaagctcgt
    25441 gcagccttgg tagagcttga gcaacaaatc caagaacaag aattaggtgt caatacgaat
    25501 ctgacacttg atcaatattg ggatatttat tctaaaaaga gattgtcaac agggcgctgg
    25561 aatgacactt cctactacct caatgataac ctctataaga atcatatcaa aaccaaattt
    25621 ggttctattc agcttaaaaa tttggataga aatgagtatg aactctttat cgctgaaaag
    25681 ttgcagaacc ataccagata cactgttcaa accctcaatt ccagcttcat ggcattgctg
    25741 aatgatgccg tgaaaaatgg taatctgctc tcaaatcgct tgaaaggtgt tttcatcggc
    25801 cagagtgata tccctgctgc aaacaagaaa gtgactctca aagagttcaa gacttggata
    25861 gcaaaggcag aagagattat gccaaaacaa ttctacgctc tgacctatct gacaattttt
    25921 ggattgagaa gaggagaagt ctttggattg cgtccaatgg acatcactca gaacgacagc
    25981 ggacgggcta tactgcatct tagagacagt cgaagcaacc agaccttaaa agggaaagga
    26041 gggcttaaaa cgaaggattc agagcgatat gtctgccttg atgatatcgg aacagacctg
    26101 atctattatc tgatagctga agcttctaag attaagcgaa agttaggaat tatcaaggaa
    26161 cagcacaagg attatataac tatcaacgag aaaggtggtc tcatcaatcc aaatcagcta
    26221 aatagaaact tcaatctagt gaatgaagca acaggattgc atgtaacacc tcacatgatg
    26281 cgccacttct tcacgactca aagcattatt gcaggggttc cgcttgaaca attaagccag
    26341 gcgctggggc atacaaaggt ttatatgacg gatcgttaca atcaagtaga ggacgaactt
    26401 gctgaagcga caacagacct atttcttagt catattcgct aaaaaagtcc ccgccaattc
    26461 cccgaccaaa atccgaaaaa taccgaaaaa tatcgaaaaa ttatttttag aatagtcccc
    26521 aaaagcctga aatagagcta aaaaactcca cctgattcgg tggagttaag ggagattatt
    26581 atgaaaaaga aaagtttagg atatttgtta caacaagtta ggaggtcttc ttgtaaccgt
    26641 ctatagtata cccgacctat cttaaacaaa tcttaaaaat ctcttaggac caaacacttt
    26701 ctaaaatatt tgtttgttca cgaccaggac ctactgagaa agtagaaata cgaacgccaa
    26761 ccaattcact cacacgacga acatagttac gcgcattctc aggaagatct tccaaattgc
    26821 gaactccggt aatatcttct gaccaacctg gcaactcttc atagataggc ttgcaacgtt
    26881 tcaattgctc aagactagct ggatagtagt caatacgttg accgtcaaga tcataggcca
    26941 cacagatttt cacagtatcc aaaccgctca aaacatcaat agagttcaaa gaaaggttag
    27001 taataccaga aacacgacgg ctatgacgca tcacaactga gtcaaaccaa cctacacgac
    27061 gtggacgacc agttgttgta ccatactcat gacccacttc acggatacgt tctcccactt
    27121 catcaaacaa ctcagttggg aaaggaccat ctcctacacg actcgtataa gctttacata
    27181 cacctacaac cttgtcaatc ttgcttggac cgacaccaga accaattgtc acaccaccag
    27241 ctacagggtt tgatgacgta acaaatggat aagtaccttg gtcgatatct agcataacac
    27301 cttgtgcacc ttcaaaaagc acacgtttgc cattatcaag cgcatcattc aagataacag
    27361 atgtatctat cacgtatttc ttgatttgtt gaccatattc gtaatattct tcaaaaatat
    27421 catcgaaaac aatcgcttta ctgtcataca atttttcaaa aagacgattc ttttcagcaa
    27481 ggttacgttc taaacgctca cggaaaatat ctttatctaa aagatctgca atacgaattc
    27541 caacacgagc agccttgtcc atataagctg gaccaattcc cttaattgtc gtaccaatct
    27601 tattgtcgcc cttagcttct tcttgcaagc gatccaactc gatatgataa ggcaaaataa
    27661 catgcgcacg atcagaaata cgcaagttat cagttgttac accttcctca tgaagatagc
    27721 tcaactcttt tacaagagat ttaggattta caaccatacc attcccaatg acagatattt
    27781 tttcagggaa gaaaatccca gatggaatca agtgcaactt aaatttctta ccgtcaatca
    27841 caatcgtgtg accagcatta tcaccacctt ggtaacgtgc aatcacttct gcattcgctg
    27901 aaaggaagtc tgtaatcttc cctttacctt catcacccca ttgggtacct acaacaacaa
    27961 ctgaagtcat aatcttgtct gagccctcag gctcttcctt tctcacatac atggcaggac
    28021 tctcacctgc aattatatct tacaatttat tataataaaa aatcgtcttt ttatcaagaa
    28081 gaaacaatag aaagatttgc tatttccaac tattaaaaaa tgatttagaa aaattactag
    28141 ctatttacta tcatctttcc ataaaagagt aaattagttc ggaaatttac taaaattacc
    28201 tcaacaagaa ataaaacccc gattcattac caatttttca agatacaaac gataagcaac
    28261 acgataatgg taaacaataa aatccttacg acaaccaatg ccatatctca ctaaataata
    28321 aattaaaaat ttaaaatgaa catgttccca gtcaaaatta tcaccaaatg taggaccata
    28381 ctcttcttca atactatcat agaaattagc catctgctca taaatttttt gtaacataat
    28441 caaatactcc ttttcttttt tataaactta ttctaacaaa aaattttaca cattcactat
    28501 caattcctga attgttaaaa taccagcctc aacaagataa aaataggaaa agttgacaga
    28561 atagaaacaa atttgctacc taaatttcaa acgattaaag ttctaaaaag accgccttaa
    28621 aacttttggg taaatcctat tagaactata atatttttat ataggtatta tggttctgat
    28681 tttctagtat aaaaaattca aactagaatt cttcttagaa aaggccgttt taagtgctat
    28741 cactgttcaa aaatgagggt cgctgaaact tctatcgtca agaagaatca tcaaattcct
    28801 tgtatcatca accaaaagat tgctcagaag ctaattaaaa agacttctat gaccgacatt
    28861 gatcatcagt tgtctatttc aacttcaact gtcattcgca agatcaatga ttttcacttt
    28921 gagcatgatt tttcgcgtct tcctgagatt atgtcctagg acgttgaaac agtccgggga
    28981 gtgactgttt caatcgggag atggagatga gctttattgc tcaagacttt gataagctca
    29041 atatcataac tgttcttgag agcagaacac aagccatcat ccgaaatccc atgaatacaa
    29101 ggctatcaag cgatactgaa agctcattca acaagatagt cagaaactga gtgataaacg
    29161 attttatcgc cctacttttc gtatgcactt gactaataaa gaaattctag ataaactttt
    29221 gagctattcc gaagacttga aacaccacta taatctctat cagctcttgc ttttccacct
    29281 ctttttcaga ctctgtttaa aaccttcctc aaagataaag agaaaatcgt caacgccctt
    29341 caattacctt attccaacgc caaactggaa gccaccaata atctcatcaa acttatcaag
    29401 tacaatgcct ttggttttag gaactttgaa aacttcaaaa aagaaaggac gaaatttgtc
    29461 ctttctagat cttcgctttc ttcaacccac tacagttgac aaagaaccga aaaatgtctc
    29521 gcctctaata tagtcaattg aaacaagaac aagacaaaag agcctcataa aaggtattgc
    29581 aacttgctaa tacctttttg gggttctttt tgatatgaac ccatgttttc tcaataggat
    29641 tgtactcagg tgagtaggga ggaagaggta aaagtttatg cccaaactct tcacacaaga
    29701 gttctagctt acccattcta tggaatcttg cattgtccat aatatagtag attgaaacta
    29761 gaatagtaca cctctacttc taaaacattg ttagaattcg attttactgt cctgatcgat
    29821 ttgtcctatt cttatttcat tttactataa cacgaaatag attattatta cataacaaaa
    29881 aagaggtcta aacctcttaa ctaaattact ccgccagtag gactcgaacc tacgacatca
    29941 tgattaacag tcatgcgcta ctaccaactg agctatggcg gatta
//
LOCUS       DAVHKZ010000028        29310 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000028 DAVHKZ010000000
VERSION     DAVHKZ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29310
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.028"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            186..416
                     /gene="blpU"
                     /locus_tag="VVO74_001487"
     CDS             186..416
                     /gene="blpU"
                     /locus_tag="VVO74_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEU5695495.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            1131..3284
                     /locus_tag="VVO74_001488"
     CDS             1131..3284
                     /locus_tag="VVO74_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU5695496.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLFSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNSLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3297..4646
                     /locus_tag="VVO74_001489"
     CDS             3297..4646
                     /locus_tag="VVO74_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU5695497.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQSEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQFFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4816..5523
                     /locus_tag="VVO74_001490"
     CDS             4816..5523
                     /locus_tag="VVO74_001490"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU5695498.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIVG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5725..9450
                     /locus_tag="VVO74_001491"
     CDS             5725..9450
                     /locus_tag="VVO74_001491"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU5695499.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFTQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVCVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEAANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9543..10985
                     /locus_tag="VVO74_001492"
     CDS             9543..10985
                     /locus_tag="VVO74_001492"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU5695500.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            11022..12044
                     /locus_tag="VVO74_001493"
     CDS             11022..12044
                     /locus_tag="VVO74_001493"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU5695501.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            12041..12586
                     /gene="purN"
                     /locus_tag="VVO74_001494"
     CDS             12041..12586
                     /gene="purN"
                     /locus_tag="VVO74_001494"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU5695502.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12670..13179
                     /locus_tag="VVO74_001495"
     CDS             12670..13179
                     /locus_tag="VVO74_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU5695503.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            13204..14751
                     /gene="purH"
                     /locus_tag="VVO74_001496"
     CDS             13204..14751
                     /gene="purH"
                     /locus_tag="VVO74_001496"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU5695504.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDATYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14873..16135
                     /gene="purD"
                     /locus_tag="VVO74_001497"
     CDS             14873..16135
                     /gene="purD"
                     /locus_tag="VVO74_001497"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU5695505.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKTFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16326..16817
                     /gene="purE"
                     /locus_tag="VVO74_001498"
     CDS             16326..16817
                     /gene="purE"
                     /locus_tag="VVO74_001498"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU5695506.1"
                     /translation="MTKPIISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTP
                     DLMFKHAEEAYSRGIKVIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYS
                     IVQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSN
                     ELI"
     gene            16804..17895
                     /gene="purK"
                     /locus_tag="VVO74_001499"
     CDS             16804..17895
                     /gene="purK"
                     /locus_tag="VVO74_001499"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU5695507.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPVSRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEVD
                     LEAAYALAESADCVLEEFVNFALEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVAENPSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            17905..18132
                     /locus_tag="VVO74_001500"
     CDS             17905..18132
                     /locus_tag="VVO74_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEU5695508.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            18195..19493
                     /gene="purB"
                     /locus_tag="VVO74_001501"
     CDS             18195..19493
                     /gene="purB"
                     /locus_tag="VVO74_001501"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU5695509.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19548..23486)
                     /gene="strH"
                     /locus_tag="VVO74_001502"
     CDS             complement(19548..23486)
                     /gene="strH"
                     /locus_tag="VVO74_001502"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU5695510.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKADVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYDDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKIISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAVTHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQEEDIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKVLPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(23799..24515)
                     /locus_tag="VVO74_001503"
     CDS             complement(23799..24515)
                     /locus_tag="VVO74_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU5695511.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIEFISCDRDH"
     gene            24863..26650
                     /locus_tag="VVO74_001504"
     CDS             24863..26650
                     /locus_tag="VVO74_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU5695512.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYIAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEERGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26647..27123
                     /locus_tag="VVO74_001505"
     CDS             26647..27123
                     /locus_tag="VVO74_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU5695513.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            27151..28056
                     /locus_tag="VVO74_001506"
     CDS             27151..28056
                     /locus_tag="VVO74_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU5695514.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            28043..28858
                     /locus_tag="VVO74_001507"
     CDS             28043..28858
                     /locus_tag="VVO74_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU5695515.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28865..29269
                     /locus_tag="VVO74_001508"
     CDS             28865..29269
                     /locus_tag="VVO74_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU5695516.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
BASE COUNT         8053 a         5725 c         6899 g         8633 t
ORIGIN      
        1 tagtaaaaaa gtgattagaa aacatctttt ttaaaaatag agatgatttt gaaacaaaaa
       61 agctaattca agacgtttcg atgccaattc aagatttgga tgaaaaaaat taatagatac
      121 tgttatacta aacttgtcaa gtttgtaaca agacaaatat taaaaataaa aaagaggtat
      181 tcgttatgaa tacaaaaaag atgtcacaat ttgaaattat ggatactgag atgcttgctt
      241 gcgttgaagg tggcggatgc aattggggag attttgccaa agcaggtgtt ggaggaggag
      301 cagcacgagg tcttcagcta ggaattaaaa caagaacatg gcaaggtgca gcaactggtg
      361 ctgcgggagg agctatactt ggaggtgtgg cctatgcagc gacatgttgg tggtaattat
      421 ggattttaaa agttttatta ttggtttagt agttggtata tttggtcctt atatggatga
      481 tttaattaga aaaaaatttt taaagtcttc ggagaagaaa acagaaaaat ctgttaaaaa
      541 ataatcaaaa ctataaatga tgaatctgaa tcaaaattat tttgcgcatg taaagaggag
      601 tcttatagta acgagtcaaa aaaggagtaa ctatgaatcg taatttagaa cggtgttatc
      661 tattctgact aggaatagat cataccagag gtagcttaga aatagcagag acattagaaa
      721 ttgaagtaat aaataggatg tcgtaagtgt tactatcaat gatttatttg tttcaagctt
      781 gcctagggtg acagtaaaaa atcaatttcc tttcaatagc atatttttag tgggcaggac
      841 tcttgttctg cctatttttt tatccaaaaa gtgcagttgg gagggagata ggctcatttg
      901 ggaaggaagt ccagtttttg tttagtgatt ggggtaagat agttgttatc agatgagttt
      961 atactcttcg aaaatcaaat tcaaaccacg tcaacgtcgc cttgccgtat atatgtgact
     1021 gacttcgtca gtcctatcta caacctcaaa acagtgtttt gagcagcctg cggctagttt
     1081 cctagtttgc tctttgattt tcattgagta ttagggaaaa ggagatgaat atgaaatttg
     1141 ggaaacgtca ctatcgtccg caagtggatc agatggactg cggtgtagct tcattagcca
     1201 tggtttttgg ctactatggt agttattatt ttttggctca cttgcgagaa ttggctaaga
     1261 cgaccatgga tgggacgacg gctttgggct tggtcaaggt ggcagaggag attggttttg
     1321 agacgcgagc cattaaggcg gatatgacgc tttttgactt gccggatttg acttttcctt
     1381 ttgttgccca tgtgcttaag gaagggaaat tgctccacta ctatgtggtg actgggcagg
     1441 ataaggatag cattcatatt gccgatccag atcccggggt gaagttgact aaactgccac
     1501 gtgagcgttt tgaggaagaa tggacaggag tgactctttt tatggcacct agtccagact
     1561 ataagcctta taaggaacaa aaaaatggtc tgctctcttt tatccctata ttagtgaagc
     1621 agcgtggctt gattgccaat atcgttttgg caacactctt ggtaaccgtg attaacattg
     1681 tgggttctta ttatctgcag tctatcattg atacctatgt gccagatcag atgcgttcga
     1741 cactagggat tatttctatt gggctagtca tcgtctacat cctccagcaa atcttgtctt
     1801 acgctcagga gtatctcttg cttgttttgg ggcaacgctt gtcgattgac gtgattttgt
     1861 cctatatcaa gcatgttttt cacctcccta tgtccttctt tgcgacacgc aggacagggg
     1921 agatcgtgtc tcgttttaca gatgctaaca gtatcatcga tgcgctggct tcgaccatcc
     1981 tttcgatttt cctagatgtg tcaacggttg tcattatttc ccttgttcta ttttcacaaa
     2041 ataccaatct ctttttcatg actttattgg cgcttcctat ctacacagtg attatctttg
     2101 cctttatgaa gccgtttgaa aagatgaatc gggataccat ggaagccaat gcggttctgt
     2161 tttcttctat cattgaggac atcaacggta ttgagactat caagtccttg accagtgaaa
     2221 gtcagcgtta ccaaaaaatt gacaaggaat ttgtggatta tctgaagaaa tcctttacct
     2281 atagtcgagc agagagtcag caaaaggctc tgaaaaaggt tgcccatctc ttgcttaatg
     2341 tcggcattct ctggatgggg gctgttctgg tcatggatgg caagatgagt ttggggcagt
     2401 tgattaccta taataccttg ctggtttact ttaccaattc tttggaaaat atcatcaatc
     2461 tgcaaaccaa gcttcagaca gcgcaggttg ccaataaccg tctaaatgaa gtgtatctag
     2521 tagcttctga gtttgaggag aagaaaacag ttgaggattt gagcttgatg aagggagata
     2581 tgaccttcaa gcaggttcat tacaagtatg gctatggtcg agacgtcttg tcggatatca
     2641 atttaaccgt tccccaaggg tctaaggtgg cttttgtggg gatttcaggg tcaggtaaga
     2701 cgactttggc caagatgatg gttaattttt acgacccaag tcaaggggag attagtctgg
     2761 gtagtgtcaa tctcaatcag attgataaaa aagccctgcg ccagtacatc aactatctgc
     2821 ctcaacagcc ctatgtcttt aacggaacga ttttggagaa tcttcttttg ggagccaagg
     2881 aggggacgac acaggaagat atcttacggg cggtcgaatt ggcagagatt cgagaggata
     2941 tcgagcgcat gccactgaat tatcagacag aattgacttc ggatggggca gggatttcag
     3001 gtggtcaacg tcagagaatc gctttggcgc gtgctctctt gacagatgcg ccggtcttga
     3061 ttttggatga ggcgactagc agtttggata ttttgacaga gaagcggatt gtcgataatc
     3121 tcatagcttt ggacaagacc ttgattttca ttgctcaccg cttgactatt gctgagcgga
     3181 cagagaaggt agttgtcttg gatcagggca agattgtcga agaaggaaag catgctgatt
     3241 tgcttgcaca gggtggcttt tacgcccatt tggtcaatag ctagaaagag gagaggatga
     3301 aaccagaatt tttagaaagt gcggagtttt ataatcgtcg ttaccataat ttttccagta
     3361 gtgtgattgt acccatggcc cttctgctcg tgtttttact tggctttgca actgttgcag
     3421 agaaggagat gagtttgtcc actagagcta ctgtcgaacc cagtcgtatc cttgcaaata
     3481 tccagtcaac tagcaacaat cgtattcttg tcaatcattt ggaagaaaat aagctggtta
     3541 agaaggggga tcttttggtt caataccaag aaggggcaga gggtgtccaa gcggagtcct
     3601 atgccagtca gttggacatg ctaaaggatc aaaaaaagca attggagtat ctgcaaaaga
     3661 gcctgcaaga aggggagaac cactttccag aggaggataa gtttggctac caagccacct
     3721 ttcgcgacta catcagtcaa gcaggcagtc ttagggctag tacatcgcaa caaaatgaga
     3781 ccatcgcgtc ccagaatgca gcagctagcc aaacccaatc cgaaatcggc aacctcatca
     3841 gtcaaacaga ggctaaaatt cgcgattacc agacagctaa gtcagctatt gaaacaggtg
     3901 cttccttggc cggtcagaat ctagcctact ctctttacca gtcctacaag tctcagggcg
     3961 aggaaaatcc ccaaactaag gttcaggcag ttgcacaggt tgaagcacag atttctcagt
     4021 tagaatctag tcttgctact taccgtgtcc agtatgcagg ttcaggtacc cagcaagcct
     4081 atgcgtcagg gttaagcagt caattggaat cccttaaatc ccaacacttg gcaaaggttg
     4141 gtcaggaatt gacccttcta gcccagaaaa tcttggaggc agagtcaggt aagaaggtac
     4201 agggaaatct tttagacaag gggaaaatta cggcgagtga ggatggggtg cttcatctta
     4261 atcctgagac cagtgattct agcatggttg cagaaggtgc cctactagcc caactttatc
     4321 catctttgga aagagaaggg aaagccaaac tcacagccta tctaagttca aaagatgtag
     4381 caagaatcaa ggtcggtgat tctgttcgct atactacgac tcatgatgcc gggaatcaat
     4441 tttttctaga ttctactatt acaagtattg atgcgacagc tactaagact gagaaaggga
     4501 atttctttaa aatcgaggcg gagactaatc taacttcgga gcaggctgaa aaacttaggt
     4561 acggggtgga aggccgtcta cagatgatta cgggcaagaa aagttatcta cgttattatt
     4621 tggatcaatt tttgaacaaa gagtaatgtt cgtgttttta gagttaaata atttttaaac
     4681 tgtgagaaag attcttcttg cagttttttc tttacaattt ttgaaaaaca tatgctattt
     4741 attcggttaa attcttgtgt tttttggttt tttgtggtaa aatgtgctca agtaatacga
     4801 aaggcgaact ttaaaatgtc aaaacaattg atctattcgg gaaaagctaa agatatctat
     4861 acaactgagg atgaaaatct tattatttca acttacaagg accaggcgac tgctttcaac
     4921 ggtgtcaaga aggagcagat tgtaggtaag ggagtcttga ataatcagat ctcatctttt
     4981 atttttgaga aattaaatgc ggctggtgtg gcgactcact ttgtggagaa actttcagac
     5041 acggaacaac tcaataaaaa ggttaagatt attcctttgg aagtcgtgct ccgcaactat
     5101 actgctggtt ccttttcaaa acgttttggt gtggatgagg gaatcgcctt ggagactccg
     5161 attgtcgaat tttactacaa aaatgatgat ttggatgatc catttatcaa tgatgagcat
     5221 gtgaaattcc tacagattgc gggtgaccag cagattgcct acttgaagga agaaacgcgt
     5281 cgtatcaatg aactattgaa agtctggttt gctgagattg ggcttaaatt gattgacttt
     5341 aagctagagt tcggttttga caaggatggc aagattatct tggcagacga attttcacca
     5401 gataactgcc gcttgtggga cgctgatggc aaccacatgg ataaggatgt tttccgtaga
     5461 ggattgggag aactaaccga cgtttatgag attgtttggg aaaagttgca ggaattgaaa
     5521 taatctgttt gcaacggaaa accttcgtct ctcaactaaa aggactcagg ctgaaaaggt
     5581 cccccagacc ttttcactct gtagagaact aggtgaacta acagatgttt acgaaattgt
     5641 ctgggaaaag ttgcagggtt taaaataaca acctcaaggc tgtttgggaa tattgcaaga
     5701 gctgaaataa aggaataaga attgatggat aaacgtattt ttgttgaaaa aaaggctgat
     5761 tttcaggtca agtcagagag tttggttaga gagctccagc acaacttggg actgtcaagc
     5821 ttgaaaagta ttcgtattgt gcaagtatat gatgtatttg acttggctga ggacttgttt
     5881 gcacctgcag agaagcacat tttctctgag cagggaaccg accatgtttt agatgaagta
     5941 tctgtgcagg cggatcttgc taactatgct ttctttgcca ttgaaagtct gccagggcag
     6001 tttgaccagc gtgcagcttc gtcacaggaa gccttgcttt tgttgggaag ttcgagtgac
     6061 gtgacagtca acacagccca actttacttg gtgaataaag atattgatgc gactgagttg
     6121 gaagctgtca aaaactacct gctcaatcca gttgattctc gtttcaagga tatcacgaca
     6181 gggattgcca agcaggagtt ttcagagtca gacaagacca ttccaaaatt gactttcttt
     6241 gaaagctata cagcagaaga ctttgctcgc tacaaggccg agcaagggat ggccatggaa
     6301 gtggatgatt tgctctttat ccaagactac tttaagtcaa tcgggcgcgt gccaactgag
     6361 actgaactca aggttttgga cacttactgg tctgaccact gccgtcatac gacttttgag
     6421 acagagttga aacacatcga cttttcagct tctaaatttc aaaagcaatt gcagtcaacc
     6481 tatgacaagt atattgccat gcgcgaggag ttaggtcggt ctgaaaaacc acaaaccttg
     6541 atggatatgg cgactatttt cggtcgttat gagcgtgcta atggacgatt ggatgatatg
     6601 gaagtctctg acgaaatcaa tgcctgctca gttgaaattg aagtggatgt tgatggtgtc
     6661 aaggaacctt ggctcctcat gtttaaaaat gaaacccaca accatccaac agaaattgag
     6721 ccatttggtg gagcggctac ctgtatcggt ggagctattc gtgatccgtt gtcaggccgt
     6781 tcctatgttt accaagccat gcgtatttca ggtgctggtg atattacagc accgatttcg
     6841 gaaactcgtg ctgggaaatt gccacaacaa gtcatttcta aaacagcagc tcatggttat
     6901 tcttcatatg gtaaccagat tgggcttgcc acaacctacg ttcgtgaata cttccaccca
     6961 ggctttgtag ctaaacgtat ggaacttggt gccgttgttg gtgcggctcc caagggcaat
     7021 gttgtccgtg aaaaacctga agcaggtgat gtgatcatcc ttctcggagg caaaacaggt
     7081 cgtgatggtg tcggtggtgc gacgggctct tctaaggttc aaacagttga gtctgtagag
     7141 actgctggtg ctgaggttca aaaaggaaat gccatcgaag aacgcaagat tcagcgcctc
     7201 ttccgtaatg gcaatgtcac tcgtctgatc aagaagtcca atgactttgg ggcaggcggc
     7261 gtctgtgtgg ctatcggtga attggcagac ggtcttgaaa tcgacctcaa caaggtgcct
     7321 cttaaatacc agggcttgaa tggtacagaa attgccatct ctgaatcaca agaacggatg
     7381 gcggtcgtgg ttcgtcctga agatgtggat accttcgttg ccgaatgtaa caaagaaaat
     7441 attgatgctg ttgtggtggc gacagtaact gaaaaaccaa atcttgtcat gcactggaat
     7501 ggtgagacaa tcgttgactt ggagcgtcgt ttccttgaca ccaatggtgt gcgcgtggtt
     7561 gtcgatgcca aagttgtgga caaggatgtc aaactcccag aagagcgtca aacatctgct
     7621 gaaacactgg aatcagatac ccttacggtt ctatctgacc tcaaccatgc aagtcaaaaa
     7681 ggattacaga ctatctttga ctgctctgtt ggacgctcaa cggttaatca cccacttggt
     7741 ggtcgttacc aactcacacc aactgaggca tctgtgcaga aattgccagt tcaacacggt
     7801 gtgactcata ctgcgtcggt cattgctcaa ggtttcaacc catatgtagc tgaatggtct
     7861 ccataccacg gtgctgctta tgcggttatc gaagcaactg ctcgtttggt ggctgctggt
     7921 gccaactggt ccaaggctcg tttctcttac caagagtatt tcgagcgtat ggataaacaa
     7981 gcagagcgtt tcggtcagcc agtagctgct cttctaggtt ctattgaagc acaaattcag
     8041 cttggcttgc catctatcgg tggtaaggac tccatgtctg gtacctttga agaattgacc
     8101 gttccgccaa ccttggttgc ctttggggtg acgacggcag atagccgtaa ggtgctctct
     8161 ccagaattta aagctgttgg ggaaaatatc tactacatcc caggtcaagc cctctctgca
     8221 gagattgatt ttgacttgat taagaaaaat tttactcagt ttgaagccat ccaagctgac
     8281 cataaagtga catctgcatc agctgtcaaa tacggtggtg tagttgaaag tttggctctt
     8341 gctacctttg gaaactatat tggtgcagag gtgaccttgc ctgaacttaa aacagctttg
     8401 acagctcaat taggcggctt tgtcttcaca tctcctgaag aaattgctgg agtagagaag
     8461 gttggacaaa cgaaagcaga ctttacactg actgtcaacg gtgtgaagct agatggacac
     8521 aagcttgaca gtgcatttca agggacattg gaagaagttt acccaacaga atttacccaa
     8581 gcgaaagaac tagaagaagt accagctgtg gcatcagatg ttgtgattaa agccaaagaa
     8641 aaggttgaaa aacctgtggt ttacatccca gtctttccag gaaccaactc agaatatgat
     8701 tcagctaagg ccttcgaaaa agaaggtgca gaggtcaatt tggtgccatt cgtgaccttg
     8761 aatgaagaag ctattgtcaa gtcagttgaa actatggttg acaatatcga caagactaat
     8821 attctcttct ttgctggtgg attctcggct gcggatgaac cagatggttc agctaagttt
     8881 atcgtcaata tcctgcttaa tgaaaaagtg tgtgtggcta ttgatagctt tatcgcccgt
     8941 ggtggtttga ttatcggtat ttgtaatgga ttccaagcct tagtcaaatc gggtctccta
     9001 ccctacggaa actttgaagc tgctaacagt actagcccaa ccctcttcta caatgatgcc
     9061 aaccaacacg tggccaagat ggtggaaact cgcattgcca ataccaactc accatggttg
     9121 gctggtgtgc aagtgggcga tatccacgct attcctgttt cgcacggtga agggaagttt
     9181 gtcgtgacgg ctgaggaatt tgcagagctc cgtgacaatg gacaaatttt cagccaatac
     9241 gttgacttta acggtaaacc aagtatggat tctaagtaca atccgaatgg ttctgtccat
     9301 gccatcgaag gaattaccag caagaatggt caaatcatcg gtaagatggg ccactcagaa
     9361 cgttatgagg atggtctttt ccaaaatatc ccaggcaata aagaccaaca cctgttcgca
     9421 tcagcggtta aacatttcac tggaaaataa gacttacaga ttttctaata gatagtatca
     9481 gtaatgtaaa agtcatgtaa atctagctct tgatgattac aaatgaaaat taggtataaa
     9541 aaatgacata cgaagtaaaa tctcttaatg aagaatgtgg tgttttcggt atttggggac
     9601 atccagatgc tgctaagttg acctattttg gactccacag tcttcaacac cgtggtcagg
     9661 agggggcagg aatcctctcc aatgatcaag gacaactgaa gcgccatcgt gacatggggc
     9721 ttttatcaga agttttcaga aatccagcca atttggataa attgacagga gctggtgcga
     9781 ttgggcatgt gcgttatgcg actgctggcg aagcttctgt tgataacatc caacccttcc
     9841 tcttccgttt tcacgatatg cagtttggtt tggctcataa tggaaatctg accaatgcag
     9901 cctctctcaa gaaagaactg gaacaaagag gagcaatttt cagcgcgact tcggactctg
     9961 aaatcttggc tcacctcatt cgtcgcagtc ataatcctag cctgatgggc aaaatcaagg
    10021 aagcgctcag ccttgtcaaa ggtggttttg cctatatctt gctgtttgag gacaagttga
    10081 ttgcggctct tgaccctaat ggctttcgtc cgctttctat cgggaaaatg gccaacggag
    10141 cggtggttgt ttcctctgaa acctgtgctt ttgaggtcat tggtgccgag tggattcgtg
    10201 atttgaagcc aggtgagatt gtgatcattg atgacgaggg cattcagtat gacagctata
    10261 cagatgatac ccagttggcg atttgttcta tggagtatat ctactttgcc cgccctgatt
    10321 ctaatatcca cggtgtcaat gtccatacgg cacgtaagag aatgggagcg caattggcgc
    10381 gagaatttaa gcatgaggca gatattgtag ttggtgtgcc caattcttcc ctaagcgcgg
    10441 ctatgggatt tgcggaagaa tcaggcttac caaatgaaat gggtctgatc aaaaaccaat
    10501 acacccagcg aacttttatc caaccgactc aagaattgcg ggagcaagga gtgcggatga
    10561 aactgtctgc tgtttcgggt gttgtcaaag gcaaacgtgt ggttatggtg gatgattcca
    10621 ttgtacgtgg aacaacctct cgtcgtatcg ttcagctctt gaaagaagcg ggtgcgactg
    10681 aggttcacgt tgccattgga agtcctgcac tagcgtatcc atgtttctac gggattgata
    10741 tccagacccg tcaggagctg attgcagcca atcatacggt cgaagaaact cgccaaatca
    10801 ttggtgcgga cagtctgact tatctttcaa ttgatagctt gattgagtcg attggtatcg
    10861 aaacagatgc gccgaacggt ggtctctgtg tcgcttactt tgacggtgac tacccaacgc
    10921 ctctctatga ctacgaagaa gactatcgta gaagtttgga agaaaagacc agtttttaca
    10981 agtaggcgac agattctcca ttaaagaaaa ggaaaaaaca aatgacaaat aaaaatgcat
    11041 atgcccagtc gggtgtggat gttgaagcgg gttatgaagt tgttgaacgg attaaaaagc
    11101 acgtggcccg tacggagcgt gcaggtgtca tgggagctct tggtggcttt ggtggtatgt
    11161 ttgacctttc caagactggg gttaaagaac ccgtcttgat ttcagggact gacggtgtcg
    11221 gaaccaagct catgttggct atcaagtacg acaagcacga taccatcggg caggactgtg
    11281 tggccatgtg tgtcaacgac atcattgctg caggtgcgga acccctctat tttctcgact
    11341 acgtagcgac agggaagaat gaaccagcta agctagaaca agtggttgct ggtgtggcag
    11401 aaggttgtgt gcaggctggt gctgccctca tcggtgggga aacggctgaa atgccgggca
    11461 tgtacggcga agacgactat gacttggctg gttttgcggt cggtgtggct gaaaaatctc
    11521 aaatcattga cggttcaaag gtggtagagg gagatgttct tctcggactt gcttcaagtg
    11581 ggattcactc aaatggttac tctttggttc gtcgtgtctt tgcggattac acaggtgagg
    11641 aagtcctacc agaattggaa ggcaagaaac ttaaggaagt tctacttgag ccgactcgta
    11701 tctatgtcaa ggctgtcttg ccgctcatca aagaagagtt ggtcaacggc attgcccaca
    11761 tcacaggtgg tggctttatc gaaaatgtcc ctcgtatgtt tgcagatgac ctagctgctg
    11821 aaattgatga aagcaaagtt ccagtgcttc caattttcaa agcccttgaa aaatatggtc
    11881 agattaaaca cgaagaaatg tttgaaatct tcaatatggg tgtgggactt atgttggcgg
    11941 tcagccctga aaatgtagag cgtgtaaaag aattgttgga tgaagcagtc tatgaaattg
    12001 gtcgcatcgt caagaaagaa aacgaaagtg tcattatcaa atgaaaaaaa tagcggtttt
    12061 tgcctctggt aatggctcaa attttcaggt gattgccgaa gaatttccag tggagtttgt
    12121 cttttcagac catcgtgatg cctatgtgct tgagcgtgca aagcagctcg gcgttctgtc
    12181 ctatgctttt gaactcaagg agtttgagag caaggcagac tacgaagcag cccttgtcga
    12241 actcttggaa gaacaccaga ttgacttggt ttgcctagca ggctacatga aaatcgttgg
    12301 accaacctta ttgtcggctt atgaaggtcg gattgtcaac attcatccag cctacttgcc
    12361 agaatttcca ggagctcatg ggattgagga tgcttggaat gctggcgtgg gtcagtctgg
    12421 tgtgaccatt cactgggtgg attcgggtgt ggatacaggc caggtcatca aacaggttcg
    12481 tgtgccacga ctagctgatg ataccattga cagatttgaa gctcgcatcc atgaagcaga
    12541 gtacaggctg tatccggaag tagtgaaggc tctatttaca gattgacttt ttgatgattc
    12601 atatgatatc tttgatttta aattggagtc agtgtttgtt gaagacggct tcaaacggag
    12661 gtatttgtaa tattagaatc taaaaaaaca actcgatatg tattttatgt ctatctgatg
    12721 ttattaactt ggggaatctt atttaagttt gaaacaaatc ctgaatttat agcatttttc
    12781 ttagctccaa ggtatatcaa ttggattcca ttttcagaac cactaatagt cgatggaaaa
    12841 attgtttttg ctgaaatgtt atttaatctg atttccttta ttccattagg tgtttgtttc
    12901 cctttgataa aaactaattt atctagttta agaatagtcg ggacaggttt cttgattagt
    12961 ttattgtttg agtgcttaca gtatatttta gcaataggta taacagatat aacggatttg
    13021 actttaaata cgctaggtgt ctgtgtaggc ttactgattt atcaaatttt tataagagtg
    13081 ttcaaatcac agactagaaa atggatcaat atcttaggta tgcttagcct tggttttgct
    13141 tatcttgttt tactgttact gcatttaatt ggtgtttaac taatgattaa aaaggagaat
    13201 ataatgacta aacgcgtctt aatcagcgtc tcagacaaag cgggcattgt tgaatttgcc
    13261 caagaactca aaaaacttgg ttgggagatt atctcgacag gtggaactaa ggttgccctt
    13321 gataatgctg gggtggatac cattgctatc gatgatgtga ctggtttccc agaaatgatg
    13381 gacggtcgtg tgaagaccct ccacccaaat atccacgggg ggcttctcgc tcgtcgtgac
    13441 ttggatagcc acttggaagc ggctaaggac aacaagattg agctcattga ccttgtggtg
    13501 gtcaaccttt acccatttaa ggaaactatc cttaaaccag atgcgactta tgctgatgca
    13561 gttgaaaata tcgatattgg tgggccatct atgcttcgtt cagcagcgaa aaatcatgcc
    13621 agtgttacag ttgtggtaga tcctgctgac tacgctgtgg ttttggacga attggcagca
    13681 aacggcgaaa cctcttatga aactcgccaa cgtttagcag ccaaagtatt tcgtcacaca
    13741 gcggcttatg acgccttgat tgcagaatac ttcacagctc aagtgggtga aagcaagcct
    13801 gaaaaactca ctttgactta tgacctcaag caaccaatgc gttacggtga gaatcctcaa
    13861 caagacgcgg acttttacca gaaagctttg cctacagact actccattgc ttcagccaaa
    13921 cagctcaacg ggaaagaatt gtcatttaat aatatccgtg atgcagatgc tgctatccgt
    13981 atcatccgtg acttcaaaga tagtccaacc gttgtggctc tcaaacacat gaatccatgt
    14041 ggaattggtc aagctgatga catcgagact gcttgggact acgcttatga gtctgaccca
    14101 gtgtctatct ttggtgggat tgtcgtcctc aaccgtgagg tggatgctgc gacagctgag
    14161 aagatgcacg gcgttttcct cgaaatcatc attgcaccaa gctatacgga tgaagcgcta
    14221 gccattttga tcaataaaaa gaaaaacttg cgtatccttg ccttgccatt taatgctcaa
    14281 gaggctagcg aagtggaagc agaatacaca ggtgtagtcg gtggacttct cgtgcaaaat
    14341 caagacgtgg tcaaggaaag cccagctgac tggcaagtgg tgaccaaacg tcagccaacc
    14401 gagacagaag cgactgctct tgagttcgct tggaaggcta tcaagtacgt caaatcaaat
    14461 ggtattatcg tgaccaacga ccacatgaca cttggtgttg gtccaggtca aaccaaccgt
    14521 gtggcttctg ttcgccttgc cattgaccaa gccaaagatc gtctggacgg ggcggtcctt
    14581 gcttcagatg ccttcttccc atttgcggat aacgtggaag aaatcgctaa agcaggaatt
    14641 aaggccatca tccagcccgg tggctctgtc cgtgaccaag aatccatcga agcagcggat
    14701 aaatacggct tgactatggt ctttacaggt gtgagacatt ttagacatta agaagataaa
    14761 agggaagaaa acagtttctt tccttttttg gcttaaaatg ctaactgaaa caagattaaa
    14821 acgaactttt ttgatataat attggtaaat aattcgcaaa agaggttgag gaatgaaact
    14881 gcttgttgtc ggttcgggtg gtcgtgagca tgcgattgct aaaaagttac ttgaatcaaa
    14941 agatgtggaa aaagtctttg tagctcctgg gaatgatggg atgactctgg atggtttgga
    15001 attggtaaat atctctattt ccgaacattc taaattgatt gacttcgcaa agaccaatga
    15061 tgttgcttgg acctttatcg gtccagatga tgcccttgct gctggtatcg tggatgattt
    15121 taaccaagct gggcttaaga cctttggtcc gactagggct gcagcggagc tggagtggtc
    15181 caaggatttt gccaaggaaa tcatggtcaa atatggtgtt tcgacagcag cctatggcac
    15241 attttcagat ttcgaggaag caaaggctta tatcgaaaag catggtgcgc ctatcgtagt
    15301 caaggcggat ggcttggcgc ttgggaaggg tgtcgtcgtt gctgagacgg ttgagcaagc
    15361 ggtcgaagcc gctcatgaga tgcttttgga caataaattt ggtgactcag gtgcgcgcgt
    15421 ggttattgag gaattccttg aaggagagga attttcactc tttgcctttg tcaatggtga
    15481 taagttctac atcatgccaa cggctcagga ccacaaacgt gcctacgatg gcgacaaagg
    15541 gcctaacacg ggtggtatgg gtgcctatgc gccagttcca cacttaccac agagtgtagt
    15601 tgatacagcg gttgacacca ttgtcaagcc agttctagaa gggatgatta aagaaggtcg
    15661 cccttatctg ggagttcttt acgcagggct tatcctgaca gctgatggac cgaaagtcat
    15721 cgagttcaac gctcggttcg gagatccaga aactcagatt atcttgcctc gcttaacctc
    15781 tgactttgct caaaatatca cagatatcct ggatagcaag gagccaaata tcatgtggac
    15841 ggacaagggt gtgactctgg gtgtggttgt cgcatccaag ggctacccgc tagactatga
    15901 aaggggcgtt gagttgccag ccaagacaga aggcgatgtc atcacctact atgcaggggc
    15961 taagtttgcg gaaaatagca gagcactgct ctcaaacggc ggacgagttt atatgctcgt
    16021 taccacagca gataccgtca aagaagccca agccagcatc taccaagaac tatcccaaca
    16081 aaaaatagaa ggactcttct accgaacaga tatcggaagc aaggcaatta agtaaagata
    16141 taagaataac gcgccgtagt cgccaaacac gataatggtc gtcgtggtga aaagaccaga
    16201 acagtgaatg ttctggtcag ggggaaattt ggagaccgta ggctcaaagt ttaggaatga
    16261 aaccgaaggt ttgcttccgc ctccatcacc taagatcatt attaaaaaag aagaaaagga
    16321 aaattatgac caaaccaatt atttccatca tcatgggctc aaaatccgat tgggcaacca
    16381 tgcaaaaaac agcagaagtc ttagaccgct tcggtgtagc ctacgaaaag aaagttgttt
    16441 ctgcccaccg tacacctgat ctcatgttca aacatgcaga agaagcatat agccgtggta
    16501 ttaaggtcat catcgcaggt gctggaggcg cagcccactt gccaggaatg gtagctgcca
    16561 aaacaaccct tcctgtcata ggggtacctg tcaagtctcg tgctcttagt ggagtggatt
    16621 cactctattc tatcgttcag atgccgggtg gggtgcctgt tgcgaccatg gctatcggtg
    16681 aagctggagc gactaacgca gctctctttg ccctccgtct cctctctgta gaagataagt
    16741 ccattgcgga tgcacttgcc aactttgctg aagaacaagg aaaaatcgca gaggagtcgt
    16801 caaatgagct catctaaaac aatcggaatt atcggtggcg gtcaactggg tcagatgatg
    16861 gccatttctg ctatctacat gggccacaag gttatcgcgc tggatcctgc ggcggattgc
    16921 ccggtctctc gtgtggcgga aatcattgtg gcaccttata acgatgtaga cgccctccgt
    16981 cagttggcag accgttgcga tgtcctcact tacgagtttg aaaatgtcga cgctgacggt
    17041 ttggatgccg ttatcaagga tggacaactc cctcaaggga cagacctgct ccgcatttcg
    17101 caaaatcgta tttttgaaaa ggactttttg tcaaacaagg ctcaagtcac tgtggcaccc
    17161 tacaaggtcg tgacttctag cctagacttg gcagatatcg acttgtcgaa aaactatgtc
    17221 ctcaagactg cgactggtgg ctacgatggt catggacaaa aggttattcg ttcagaagta
    17281 gacttggaag cagcctatgc gctagcagaa tcagcagact gcgtcttgga agaatttgtc
    17341 aactttgccc ttgagatttc tgtcatcgtg tcaggaaatg gcaaggaggt gacgtttttc
    17401 ccagttcagg aaaatatcca ccgcaacaat atcctgtcta agaccatcgt accagcccgc
    17461 atttctgaaa gtctagtaga caaggctaaa gctatggcag tgcgaatcgc agaacaactc
    17521 aacttgtctg gaactctctg tgtggaaatg tttgcgactg atgatgacgt tattgtcaat
    17581 gaaatcgccc cacgaccaca taactctggg cactattcta ttgaagcctg tgatttctct
    17641 cagtttgaca cccatattct cggtgttctc ggagcaccat taccagtcat caaactccat
    17701 gcgccagccg ttatgctcaa tgtcctaggt caacacgtcg aggctgctga aaagtatgtc
    17761 gcagaaaatc caagcgccca cctccacatg tatggtaaaa tagaagcaaa gcataatcgt
    17821 aagatgggac atgtgacctt gtttagtgat gtaccggata gtgtggatga gcttggggaa
    17881 gggattgatt tttaggacaa gtctatgata caaattatcg ttaatacatt tattgaaaag
    17941 gataagactg gagcagttgt tgaagtgttg tatgccagtg ctgaccaaga taaggtacaa
    18001 gctaaatatg aagaactagc tgcacaatac cccgaaaatt atttagctat ctatgatgta
    18061 ccgctggata cggatttgaa tacactagat cattacccgt ctgtgtttat tggaaaagag
    18121 gagtttgagt agaaatcttg gtttacctag atagcttatt cccaacagct taagaagaaa
    18181 ggaaaaatta acacatgatc aaccgttact ctcgccctga gatggcgaat atttggagtg
    18241 aagaaaataa ataccgtgct tggcttgagg tggaaatcct ctctgacgag gcatgggctg
    18301 agttggggga aatccctaag gaagatgtgg ctttgattcg caagaaggcg gactttgaca
    18361 tcgaccgtat tttggaaatt gagcaggaga cgcgccacga tgtggtggct ttcacgcgtg
    18421 cggtttctga gactcttggt gaagagcgca agtgggttca ctatgggtta acttctaccg
    18481 acgtggtgga tactgcttat ggttacctct acaagcaggc caacgacatc atccgtcgtg
    18541 accttgaaaa cttcactaat atcatcgctg acaaggccaa ggagcacaag ttcaccatca
    18601 tgatggggcg tactcatggt gtgcacgctg agccgacaac ctttggtctt aaattggcaa
    18661 cttggtacag cgaaatgaaa cgcaatatcg agcgcttcga gcatgcggct gctggtgtag
    18721 aagctggtaa gatttctggt gcggttggga actttgccaa tatcccacca tttgtagagg
    18781 agtatgtctg cgataaactt ggcatccgtg cccaagaaat ctctacacaa gtccttcctc
    18841 gtgaccttca cgctgagtac tttgcggttc ttgccagcat tgcgacttca atcgaacgta
    18901 tggcgactga gattcgtggt ctacaaaaat ctgagcaacg cgaagtagaa gagttctttg
    18961 ctaaagggca aaaagggtct tcagcaatgc ctcacaaacg caacccaatc ggttctgaaa
    19021 atatgactgg tctggcgcgt gtcattcgtg gtcacatgat tacggcttat gaaaacgtcg
    19081 ctctctggca cgaacgcgat atttctcact catcagctga gcgtatcatc acaccagata
    19141 cgaccatttt gattgactac atgctcaacc gttttggaaa tatcgtcaag aacttgacag
    19201 tcttcccaga aaatatgatc cgaaacatga actcgacttt tggtcttatc tttagccaac
    19261 gggctatgtt gacattgatt gaaaaaggca tgacccgtga gcaagcctat gacttggtgc
    19321 aaccaaaaac agcctactct tgggacaacc aagtagactt taaaccactt cttgaggcag
    19381 attcagaagt aacatcacgt ctcacacaag aagaaatcga tgaaatcttc aacccagttt
    19441 attacaccaa acgagtggat gatatctttg aacgtcttgg actaggtgat taattaaaaa
    19501 ataaacagcg agcttcaatc tcgctgttta ttttttatcg aaaagactta gtcttctttt
    19561 cttttagtga gtccataggc tgctagtgtg gacatgagtc ctgcgactac tagtcctgca
    19621 gaatcgtgag ttcctgtttc aggaagtttt ttctctgtta ccacaggagc tggatcttga
    19681 ggaagaactt tgctttcctc agcaggagca gttgatggag ctggttggct tgggatttct
    19741 agttttggtt tttcttcagc aatagcggct tgtccgtttt catcgcctac atgtgttacc
    19801 atagttccga cttcgactat ttgagtaacg gcttcctgtg ctacgacact atttacaagt
    19861 gttttcactt ccttaccatc ggcagaagtg ctcacagagt agaagttgct acgatgtcca
    19921 ttgacgccct tagtaatgac ttgtgttttt cctttgagta agagtggatt ttcacgagtc
    19981 actgtggtaa atggaatgtc ttcttcttgg atatccagtc taggttttac ctcagtagtt
    20041 ggtgcaagac cactttcatc acccttgtga gttacaggag cgccaacttc aaccacttgg
    20101 tttataactt ctttggttac ctggctatca aggactgttt ctgttgtttt tccattttca
    20161 gtgagtacag agatgtaatg agttcgttca cctttgactc ctgctgtgat aatattttcc
    20221 tgaccggctg ggaggttagg attttctttc ttgataactt caaatggaat ttcttcagtt
    20281 cttgtgatga gttctggtct ggtttcaaca ttggcagcca cttcattttc atctaggctt
    20341 cctgaatgag ttacagctgg tttgaggcct tgaagagcgg cttttaggtt ggctacaagt
    20401 gtgtcaagct cagcttgttt attacggttg aggttgtaat ttagagctgt tttagctgcg
    20461 tcaagggcct caagactttc tttactatat ccttctaagt ttgtaggaat tttagctaat
    20521 tcttcgcgga gagcattata attagcacgg aagtagtctt tgttgtggtc tgcaaaggca
    20581 gtcatgagtt caaagatttc ctcttccttg tattcagcgc ttggtctatc tgcccagatt
    20641 gaaagcatac ttccgactgt tggaagatct acttcaggat atttggtaga agctagttga
    20701 ttgaatggtg tttttccagt attctcaata gctttcttga ggaaaccacc accatcttct
    20761 ggtttttgac caagaatgta gtaccagtca ccgttggtat tcaagaattt atagcctttg
    20821 cttgctaggt attgaggtga tgcgaggtta tatccccacc agcctttaga ccagtaagaa
    20881 atcaagacat ctttgtcaaa ctgaacatcg tccttgtctt catagtagaa gccatcgttg
    20941 aaggccattg gttgaagccc tctttctttg gccatagctg cgagggtgtt ggcatattcg
    21001 gcaaatttgc catagagttg ataccacttg aggtagtacc agccttgggc actagtcgca
    21061 tcgttggcgt attcgtcagt accaaagttg aaaatctttg ttttacctgc aaagaagtcc
    21121 atgtatttac cgatgagggc ttttacaaag ttcatcgctt cttcgttttt caagtccata
    21181 gttgtttttg aaactttatc aaagtgggct tgaggatttt taatacctaa tttttccatg
    21241 gcaaccagca tagcatccat gtgacctgga ctgttaatag ctgggatgag acctatgtcc
    21301 ttagatttag cgtattcaat tagctctgtc acttctgcct gtgttagtgc agtaccgttt
    21361 ggatcgtcgt agtaagcttt agttccttcg ataatagctt ttttaacgtc atcactagca
    21421 taggtttttc cgttggcagt aatggtcata tcatcgagta gaaagcgaag tccgtcattt
    21481 cctagaagga gatggacatc agaatatccg agctcactgg ccttgtctac gatgcgtttg
    21541 agctggttca gagtaaagta tttgcgtcca gcatcgattg agattatctt gtttttggca
    21601 agtttttcaa cctcacgttt agcttcttct tctttttgag cttcaggcgt gagggtcaag
    21661 ttgttgacag tttcttgaag tttagcaatg gcttgatcaa tcgtatcttg ttgggcacgg
    21721 ctaaggttgc tatcgagaga gcgaatagct ttttcagctt cttttacggc cgtgacgctt
    21781 tctgcagtat aacggttcag gtcttttggt acctcgttaa gtgcttgctc tgcagattca
    21841 taatcagctg cgaagtattc agcgttggca tttgcaaaat gacgcatgag tttgaagagg
    21901 cgtgatggtg aataacgtgc agatggagtg tcagcccaag cagctaccat accaccgatg
    21961 attgggatat cagctccttc tgtttttggt acagaagtga ttggtgtgtt tttaatacca
    22021 ttgagcccct gatcgagatt gtaccagcct tggccatcag cgtttcgtcc aagaacgtag
    22081 taccaagcat cattggtatt aaggatttgg tgaccttttt cagctagtag tttagaagaa
    22141 gcgacatcgt agcctcccca accaccagtc cacatagaaa cgatgatgtc tttgtcaaaa
    22201 ctaccaaagc ttgtgtcgct attgtagtag ataccgtcgt taaaggccat tggtttgaga
    22261 ccgtgcgatt ttacaatacg agcgaggtca ttggcgtagg caataaattt ttcatagcct
    22321 tttacagggt agccttcgtt tggatagtat ttatcagctt gaagcacact ccaaccttta
    22381 gcatctgtcg catcattggc atattcatca agtccgatgt tgaagatttc agtctttttc
    22441 gcgaaataag cagcatactt gtcgataagg gcttttgtaa aagcgacagc ttgttcgttg
    22501 tcaagatcga cagtacgggc tgattccttc ccaaaatagc taaagttagg gttttggatt
    22561 cccaattctt tcatggcatt gagaatcgca tccatgtgcc caggactatt tactgtcgga
    22621 atgagaccga tacctttatc tttggcatag ttaatcagat ctgtcatttg actttctgtt
    22681 aagtgattgc cgtttggatc gtcgtaataa tcatttgtac ctttttcaat ggcgcgtttg
    22741 acatcgtcac tggcataggt cttgccgtta gctgtgatgc tcatatcgtc caacatgaaa
    22801 cggagtccat catttccgac taataggtgt aaatcagtgt agccataatg tttcgcttta
    22861 tcgatgattt ccttgagctg ttctggtgag aaatatttac gtccagcatc aatagaaaca
    22921 attttctttt tcgctagttt ttcatttaca gttgcagcac gttcctttcc tgcctctgtt
    22981 tccggtttgt cagcctctgc tttcgcttca tcttttttag ctggtttatc cttgtcagtc
    23041 ttgtctgtat ttgactcttt agaatcaacc tctttcgctt cttccttttt agggctagct
    23101 tcttctgcct ttttattagc agtttctttt tcagcagaag ttggagttac cacgtctgct
    23161 ttatcactag gagttgaact aacttcctct tgtggttttt cttctgtttt tggaagacta
    23221 gctaccttat cagtagctgg agtttctgtt tctacagttt ttggagcttc tggttgaagc
    23281 tctgctttag gtgtttcctc agtccgattt tcggatgatt gaggggaatc agaaaccgta
    23341 tggatggtcg gttggttttc tgtagtagta ggagtaactc catcggctgc aacagtctgt
    23401 gcttggaagg caaatccaat tagaacagaa gctgctccta cagcgtattt acgaatagaa
    23461 aaacgctgtt gtttttcatg tttcattgca aaacctcctg attgcattgt tatattgata
    23521 gcgattatat aaatcaacgc ctttatttta tttcttatat taacgagagt caagaggaga
    23581 tgacaaaaaa ctataataag tataaaaaaa tataaaattt aaacttaaga tttcagattg
    23641 gtcgaaaata catatatata tctagtataa tttttggttc tatttctata aaatattcca
    23701 caaattatag aatcttccaa aaataggtaa gcgctacctt tttggtgtgg tataataagc
    23761 atagaaaaag cccgagcgat taggctcagg ctttcttctt agtgatcacg gtcacatgag
    23821 atgaattcaa tcttgtagta atcagatcgt ttgtaagttt cactgtattc taaaacttgg
    23881 ccagttgatt cgagtttggt gattttagtt tgtaggacag tagggaattg ttcatcgact
    23941 ccgaggactg aagccgcatg ttctggagtt ggaaagacta tttcgttgat ttcttcaaag
    24001 tgttcatcat tcatgtgaat gtggtagtct aacttgaaac gattatagat agaactatag
    24061 tattcaaggt ttggataatt tgcgttgata tattgttctg ggatgtagga tgtatggtag
    24121 atataaacga caccgtttga ttcgcggata cgttcaatct tgtagtagaa ttgatcgccg
    24181 cgtagaccca atttttccaa gtaaacaagc ttgtttccgc gttcaattga aagaacagtt
    24241 accttatcat ctttagcatt gaagagttca atatctgaaa actctacaag cttgtgtttg
    24301 cgtgcacgtg aaacgaaggt tccttttcct tgttggcgga caatatagcc atctttggca
    24361 aggtcgttta aggcgcgaac aactgtgata gagctgacat cgtacattga aatgagttct
    24421 gcttcagtgt aaaatttatc tccactgcta aactgcccag agatgatttt attttttaat
    24481 tcgtctttta tgtattgata tttgggaatt gccatatttt tacctctatt ttccttctcc
    24541 atagaaaatt ttaccataaa agcgaaaaaa atagtagtct tttgaataaa aaattagaat
    24601 aatagtttga aaaattaagc gatataggga ttgctcatat tttatcaatg tattctatac
    24661 aaaattattt taggtcctat attccgaatt taaagagcgt ttgaaatggg tctaaaaatg
    24721 tttgaaacta attgaatgtg tgtataatag taaaaatgca gtaaatatcc cgacaatttc
    24781 tattgacaat tcaaacagat tggtttataa ttaatataac aacaaatgaa agcgcaaact
    24841 ttcgcggtcg gaaggtagtt ttatgacacg atttgagata cgagatgatt tctatctcga
    24901 tggaaaatca tttaagattt tatctggtgc cattcattat tttagggttc ctccagagga
    24961 ttggtatcat tcgctctata acttgaaggc tcttggtttt aatacggtag agacttatat
    25021 tgcttggaat ttacacgagc ctcgtgaagg tgagtttcat tttgacggtg atctggattt
    25081 agagaaattt ctccaaatag cgcaggattt gggtctctac gcaattgtgc gtccgtctcc
    25141 atttatctgt gcggaatggg aattcggtgg cttaccagct tggctcttga ccaagaacat
    25201 gcgaattcgc tcatccgacc cagcatatat cgaggcagtt ggtcgctact atgatcagtt
    25261 attgccaaga ctggtgcctc gtttgttgga caatggtggc aatattctca tgatgcaggt
    25321 tgaaaatgag tatggttctt acggagaaga taaggcttac ctgagagcga ttcgacagct
    25381 aatggaagag cgtggcgtaa cctgtcctct ctttacatca gatggtccat ggcgagctac
    25441 tctgaaagct ggaaccttaa ttgaagagga cctctttgta acaggaaact ttggttctaa
    25501 ggcaccttac aacttttcgc agatgcagga attctttgat gaacatggta agaaatggcc
    25561 actcatgtgt atggagttct gggatggttg gtttaatcgc tggaaagaac cgattatcac
    25621 acgggatcct aaggaattgg cagatgcagt tcgagaggtt ttggaacaag gctctatcaa
    25681 tctttacatg ttccacggtg gtacaaactt tggtttcatg aatggttgct cggctcgagg
    25741 aactttggac ctgccacaag ttacgtctta tgattacgat gcccttctgg atgaagaagg
    25801 aaatccaact gctaaatatc ttgcagtcaa gaagatgatg gcaacacatt tttcagagta
    25861 tccgcagttg gaaccactct acaaagagag tatggagttg gatgctattc cactagttga
    25921 aaaagtttct ttgtttgaaa ccttagatag cttgtcaagt cctgtagaaa gtctctatcc
    25981 tcaaaagatg gaggagctgg gacaaagtta tggctaccta ctttatcgaa cagaaacaaa
    26041 ctgggatgca gaagaagaaa gacttcgtat cattgatggt cgagataggg cccagctgta
    26101 tgtcgatggt cagtgggtta aaactcaata tcagacagag attggggaag atatttttta
    26161 tcaaggtaaa aagaaagggc tatctaggtt agatatcttg atagaaaata tggggcgtgt
    26221 caactatggg cataagttct tagcggatac gcaacgtaag ggaattcgga caggggtctg
    26281 taaggatctg catttcttac taaactggaa acactatcca cttccactag acaatcctga
    26341 gaaaattgat ttttcaaaag gatggactca aggacaacca gccttttacg cttatgactt
    26401 tacagtcgaa gagccaaaag atacttacct agacttgtct gagtttggta agggagttgc
    26461 ctttgtcaat gggcagaatc taggacgttt ttggaacgtt ggcccaactc tctcacttta
    26521 tatccctcat agctatctca aggaaggtgc caaccgcatc attatctttg aaacagaagg
    26581 tcaatataaa gaagagattc atttaactcg taaacctaca ctaaaacata taaaggggga
    26641 aaacttatga caattgtagg atgccgtatt gatggacgtt tgatccacgg acaagtagcc
    26701 aatctttggg ctggaaaact aaatgtttca cgcattatgg ttgtagacga cgaagttgtc
    26761 aacaacgata ttgaaaagag tggtttgaaa cttgcgacac caccaggtgt gaaattgagt
    26821 attttgccag ttgagaaagc tgcagccaat attcttgctg gtaaatacga tagccaacgt
    26881 ctctttatcg tggctcgtaa accagaccgc ttccttggct tggtagaagc aggtgtacca
    26941 cttgaaaccc ttaatgttgg gaatatgtct caaacaccag aaactcgttc tattacacgt
    27001 tctatcaacg tagtagacaa ggatgtggaa gacttccaca aactggcaga aaaaggtgtt
    27061 aaacttactg ctcagatggt tccaaatgat ccaatttcag actttttgag cttattaaaa
    27121 taggaaaaaa atttttagga ggtcattgtt atgatacaat ggtggcaaat tttacttctc
    27181 actttgtact cagcttatca aatctgtgat gagttgacga tcgtttcatc tgcaggttcc
    27241 cctgtatttg ctggtttcat tactggttta atcatgggag atgtgactac tggtttactt
    27301 atcggtggta acttgcaact gttcgttctt ggggttggta ccttcggtgg tgcttctcgt
    27361 atcgacgcaa cttctggtgc ggttcttgcg acagccttct ctgtttcaca aggaattgat
    27421 gcaccgcttg ccattactac aatcgctgta ccagtagcag ctctcttgac ttacttcgac
    27481 gttcttggtc gtatgactac taccttcttc gctcaccgtg tggatgctgc aatcgaacgc
    27541 tttgactata aaggtattga acgcaactac ttgcttggtg cgattccgtg ggctctatct
    27601 cgtgcccttc cagtcttctt tgcccttgct tttggtggtg cctttgtaca atcagtagta
    27661 gacttcgttg aagcctacaa atgggttgca gatggcttga cacttgcagg acgtatgctt
    27721 ccaggtcttg gatttgcaat cttgcttcgt taccttccag ttaaacgtaa ccttcactac
    27781 cttgctatgg gatttggttt gacagctatg ttgactgttc tttactcata tgtaacaggt
    27841 cttggtggcg ctgttgctgg tatcgtaggt actcttcctg ctgaagttgc tgaaaaaatt
    27901 ggtttcgtga acaacttcaa aggtttgtct atgattggta tttctatcgt aggtattttc
    27961 cttgcagtgc ttcacttcaa aaatagccaa aaagtagctg tagcagcacc ttctacacca
    28021 tcagaaagtg gggaaatcga agatgacgaa ttctaattac aaacttacaa aagaagattt
    28081 taatcaaatc aacaaacgta gcttgtttac tttccaatta ggttggaact acgaacgtat
    28141 gcaagcttct ggttaccttt acatgatctt gcctcagttg cgtaaaatgt atggtgatgg
    28201 aactcctgaa ttgaaagaaa tgatgaaagt tcatactcaa ttcttcaata cttcaccatt
    28261 cttccatacc attatcgctg gttttgacct tgccatggaa gaaaaagatg gtgtaggttc
    28321 aaaagacgct gttaacggta tcaagacagg tttgatggga ccattcgctc ctcttgggga
    28381 tacaatcttt ggttcacttg tacctgctat catggggtca gtcgcagcaa ctatggctat
    28441 cgctggccaa ccttggggga tcttcctttg gattgcagtt gcagtagcgt atgacatctt
    28501 ccgttggaaa cagttggaat ttgcttacaa agaaggggtt aaccttatca acaacatgca
    28561 aagtaccttg acagctttga ttgacgctgc atctgtactt ggtgtcttca tgatgggtgc
    28621 tcttgtagca acagtgatta actttgaaat ttcttacaag ttgccaatcg gtgaaaagat
    28681 gattgatttc caagacatct tgaaccaaat cttcccacgt ttgcttccag caatctttac
    28741 tgcctttatc ttctggttgc ttggtaagaa aggtatgaac tctactaaag ctatcggtat
    28801 tattatcgta cttgctttgg ctctttctgc ccttggtcac tttgcacttg gaatgtaatt
    28861 ccttatgact aaatcattaa ttttggtgag ccatggtcgc ttctgtgagg agcttagagg
    28921 tagcacagaa atgattatgg gcccacaaga caacatttac acagtagctc ttcttccaga
    28981 agatggccca gaagaattta ctgctaaatt tgaagctgtt attgaaggat tggatgattt
    29041 cctagttttt gcggatcttc tcggtgggac accttgtaat gtggtgagtc gcttgatcat
    29101 ggaaggtcgt gatattgacc tttacgcagg gatgaatctt ccaatggtga ttgaatttat
    29161 caatgcgagc cttacaggcg cagatgcgga ctacaagagc cgtgctgcag aaagcattgt
    29221 gaaagttaat gacctgttag cgggcttcga tgatgacgaa gatgaataat actcttcgaa
    29281 aatctcttca aactacgtca acgtcgcctt
//
LOCUS       DAVHKZ010000029        27540 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000029 DAVHKZ010000000
VERSION     DAVHKZ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27540
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.029"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            143..2125
                     /locus_tag="VVO74_001509"
     CDS             143..2125
                     /locus_tag="VVO74_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5695517.1"
                     /translation="MKSSRLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSEEQKTSTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2426..7729
                     /locus_tag="VVO74_001510"
     CDS             2426..7729
                     /locus_tag="VVO74_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU5695518.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPRAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKVTFLVTGAETGD
                     TWVGIYSTGNASNTRSDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVAED
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSNQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(7896..10055)
                     /locus_tag="VVO74_001511"
     CDS             complement(7896..10055)
                     /locus_tag="VVO74_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEU5695519.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(10052..10648)
                     /gene="recU"
                     /locus_tag="VVO74_001512"
     CDS             complement(10052..10648)
                     /gene="recU"
                     /locus_tag="VVO74_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU5695520.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10714..11241
                     /locus_tag="VVO74_001513"
     CDS             10714..11241
                     /locus_tag="VVO74_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU5695521.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGTLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            11311..11640
                     /gene="gpsB"
                     /locus_tag="VVO74_001514"
     CDS             11311..11640
                     /gene="gpsB"
                     /locus_tag="VVO74_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU5695522.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11661..12041
                     /gene="rnpB"
                     /locus_tag="VVO74_001515"
     ncRNA           11661..12041
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VVO74_001515"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12126..13283
                     /locus_tag="VVO74_001516"
     CDS             12126..13283
                     /locus_tag="VVO74_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU5695523.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQIENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MASGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLCSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13296..14690
                     /gene="mapZ"
                     /locus_tag="VVO74_001517"
     CDS             13296..14690
                     /gene="mapZ"
                     /locus_tag="VVO74_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU5695524.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14766..16190
                     /gene="gndA"
                     /locus_tag="VVO74_001518"
     CDS             14766..16190
                     /gene="gndA"
                     /locus_tag="VVO74_001518"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU5695525.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSHKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16202..16891
                     /locus_tag="VVO74_001519"
     CDS             16202..16891
                     /locus_tag="VVO74_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5695526.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVAYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            16989..18005
                     /gene="cbpC"
                     /locus_tag="VVO74_001520"
     CDS             16989..18005
                     /gene="cbpC"
                     /locus_tag="VVO74_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU5695527.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGQFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEPKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYFGNKWYYLRSSG
                     AMVTGWYQDGLTWYYLNAGNGDMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVNYNG
                     EWVQ"
     gene            18127..19005
                     /gene="mvk"
                     /locus_tag="VVO74_001521"
     CDS             18127..19005
                     /gene="mvk"
                     /locus_tag="VVO74_001521"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU5695528.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFWVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            18987..19940
                     /gene="mvaD"
                     /locus_tag="VVO74_001522"
     CDS             18987..19940
                     /gene="mvaD"
                     /locus_tag="VVO74_001522"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU5695529.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            19927..20934
                     /locus_tag="VVO74_001523"
     CDS             19927..20934
                     /locus_tag="VVO74_001523"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU5695530.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            20918..21928
                     /locus_tag="VVO74_001524"
     CDS             20918..21928
                     /locus_tag="VVO74_001524"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU5695531.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDNS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            22005..22703
                     /locus_tag="VVO74_001525"
     CDS             22005..22703
                     /locus_tag="VVO74_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU5695532.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            22700..23695
                     /locus_tag="VVO74_001526"
     CDS             22700..23695
                     /locus_tag="VVO74_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU5695533.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FFFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            23709..24341
                     /locus_tag="VVO74_001527"
     CDS             23709..24341
                     /locus_tag="VVO74_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5695534.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            24342..24583
                     /locus_tag="VVO74_001528"
                     /pseudo
     CDS             24342..24583
                     /locus_tag="VVO74_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            24565..24819
                     /locus_tag="VVO74_001529"
     CDS             24565..24819
                     /locus_tag="VVO74_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU5695535.1"
                     /translation="MAANYLKAMQSYLKETDLPKLEQLVVTKSWWDTVDILDRVVGSL
                     VYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLAS"
     gene            24844..25110
                     /locus_tag="VVO74_001530"
                     /pseudo
     CDS             24844..25110
                     /locus_tag="VVO74_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            25260..25499
                     /locus_tag="VVO74_001531"
     CDS             25260..25499
                     /locus_tag="VVO74_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695536.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            25580..26401
                     /gene="cbpG"
                     /locus_tag="VVO74_001532"
     CDS             25580..26401
                     /gene="cbpG"
                     /locus_tag="VVO74_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEU5695537.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            26420..27442
                     /gene="cbpF"
                     /locus_tag="VVO74_001533"
     CDS             26420..27442
                     /gene="cbpF"
                     /locus_tag="VVO74_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HEU5695538.1"
                     /translation="MKLLKKMMQIALATFFFGLLATNTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSQAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLNPATGI
                     MQTGWQYLGNRWYYLHSSGAMATGWYKEGSTWYYLDAENGDMRTGWQNLGNKWYYLRS
                     SGAMATGWYQESSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAINTTVGGYYLNY
                     NGEWVK"
BASE COUNT         8434 a         4950 c         6350 g         7806 t
ORIGIN      
        1 tatagttgag ggatttttaa atgatattca tattttttgc aaagatgttg tttgaaaaat
       61 aattttcaaa aattctgaaa attctgttga caactttctg aaaagagtct ataatggaga
      121 gaaagtttta aaggagaaaa tgatgaaaag ttcaagacta tttgcccttg cgggcgtgac
      181 attattggcg gcgactactt tagctgcatg ctctggatca ggttcaagca ctaaaggtga
      241 gaagacattc tcatacattt atgagacaga ccctgataac ctcaactatt tgacaactgc
      301 taaggctgcg acagcaaata ttaccagtaa cgtggttgat ggtttgctag aaaatgatcg
      361 ctacgggaac tttgtgccgt ctatggctga ggattggtct gtatccaagg atggattgac
      421 ttacacttat actatccgta aggatgcaaa atggtatact tctgaaggtg aagaatacgc
      481 ggcagtcaaa gctcaagact ttgtaacagg actaaaatat gctgctgata aaaaatcaga
      541 tgctctttac cttgttcaag aatcaatcaa agggttggat gcctatgtaa aaggggaaat
      601 caaagatttc tcacaagtag gaattaaggc tctggatgaa cagacagttc agtacacttt
      661 gaacaaacca gaaagcttct ggaattctaa gacaaccatg ggtgtgcttg cgccagttaa
      721 tgaagagttt ttgaattcaa aaggggatga ttttgccaaa gctacggatc caagtagtct
      781 cttgtataac ggtccttatt tgttgaaatc cattgtgacc aaatcttctg ttgaatttgc
      841 gaaaaatccg aactactggg ataaggacaa tgtgcatatt gacaaagtta aattgtcatt
      901 ctgggatggt caagatacca gcaaacctgc agaaaacttt aaagatggta gccttacagc
      961 agctcgtctc tatccaacaa gtgcaagttt cgcagagctt gagaagagta tgaaggacaa
     1021 tattgtctat actcaacaag actctattac gtatctagtt ggtacaaata ttgaccgtca
     1081 gtcctataaa tatacatcta agaccagtga agaacaaaaa acatctacga aaaaggctct
     1141 cttaaacaag gatttccgtc aggctattgc atttggattt gaccgtacag cctatgcctc
     1201 tcagttgaat ggacaaactg gagcaagcaa aatcttacgt aatatctttg ttccaccaac
     1261 atttgttcaa gcagatggta aaaactttgg cgatatggtc aaagagaaat tggtcactta
     1321 tggggatgaa tggaaggatg ttaatcttgc agattctcag gatggtcttt acaatccaga
     1381 aaaagccaag gctgaatttg ctaaagctaa atcagcttta caagcagaag gtgtgacttt
     1441 cccaattcat ttggatatgc cagttgacca gacagcaact acaaaagttc agcgcgtcca
     1501 atctatgaaa caatccttgg aagcaacttt aggagcggat aatgtagtca ttgatattca
     1561 acaactacaa aaagacgaag taaacaatat tacatatttt gctgaaaatg ctgctggtga
     1621 agactgggat ttatcagata atgtcggttg gggtccagac tttgccgatc catcaaccta
     1681 ccttgatatc atcaaaccat ctgtaggaga aagtactaaa acatatttag ggtttgactc
     1741 aggggaagat aatgtagctg ctaaaaaagt aggtctatat gactacgaaa aattggttac
     1801 tgaggctggt gatgagacta cagatgttgc taaacgctat gataaatacg ctgcagccca
     1861 agcttggttg acagatagtg ctttgattat tccaactaca tctcgtacag ggcgtccaat
     1921 cttgtctaag atggtaccat ttacaatacc atttgcattg tcaggaaata aaggcacaag
     1981 tgaaccagtc ttgtataaat acttggaact tcaagacaag gcagtcactg tagatgaata
     2041 ccaaaaagct caggaaaaat ggatgaaaga aaaagaagag tctaataaaa aggctcaaga
     2101 agatctcgca aaacatgtga aataactgtt gcaaaatata agaaaggatt tagtatttcc
     2161 cttgaatgct gaatcctttt ttacatttgt aaagaaagat tctaaatgta ctgaccccca
     2221 aaagttggag cctctttttg tcagaataga gaaaattttt gttaatttta cttgtttcct
     2281 attgctttct cagctattat ttgttatatt aaaagcataa ttatttttta tttatcaggg
     2341 ttaagcattg cactttcaga ggaaggagta ttttttaaaa aggaaatgta aacgcttgct
     2401 aaaaaatgaa aggatttaga agtttatgaa taaaggatta tttgaaaaac gttgtaaata
     2461 tagtattcgg aaattttcat taggtgttgc ttctgttatg attggagctg cattctttgg
     2521 gacaagtccg gttcttgcag atagcgtgca gtctggttcc acggcgaact taccagctga
     2581 tttagctact gctcttgcaa cagcaaaaga gaatgatgga cgtgattttg aagcgcctaa
     2641 ggtgggagaa gaccaaggtt ctccagaagt tacagatgga cctaagacag aagaagaact
     2701 attagcactt gaaaaagaaa aaccggctga agaaaaacca aaagaggata aacctgcagc
     2761 tgctaaacct gaaacaccta agacggtaac ccctgaatgg caaacggtag agaaaaaaga
     2821 acaaaaggga acagtcacta tccgagaaga aaaaggtgtc cgctacaacc aactatcctc
     2881 aactgctcaa aatgataacg caggaaaacc agccctgttt gaaaagaagg gcttgaccgt
     2941 tgatgccaat ggaaatgcaa ctgttgattt aaccttcaaa gatgattctg aaaagggcaa
     3001 atcacgcttt ggtgtcttcc tgaaatttaa agataccaat aataatgttt ttgtcggtta
     3061 tgacaaggat ggctggttct gggagtataa atctccaaca actagcactt ggtatagagg
     3121 tagtcgtgtt gctgctcctg aaacaggatc aacaaaccgt ctctctatca ctctcaagtc
     3181 agacggtcag ctaaatgcca gcaataacga tgtcaatctc tttgacacag tgactctacc
     3241 agctgcggtc aatgaccatc ttaaaaatga gaagaagatc cttctcaagg cgggctctta
     3301 tggcaatgac cgtacggttg tcagcgttaa aacagacaat caagaaggcg taaaagcgga
     3361 tgatactcct gcccagaaag aaacaggtcc ggttgttgac gatagcaagg tgacttatga
     3421 tacgatccag tctaaggtac ttaaggcagt aattgaccaa gccttccctc gtgtcaagga
     3481 atacagcttg aacgggcata ctttgccagg acaggtgcaa cagttcaacc aagtctttat
     3541 caataaccac cgaatcaccc ctgaagtcac ttataagaaa atcaatgaga caacagcaga
     3601 gtacttgatg aagcttcgcg atgatgctca cttaatcaat gcggaaatga cagtacgcct
     3661 gcaagttgtg gacaatcaat tgcactttga tgtgaccaag attgtcaacc acaatcaagt
     3721 cactccaggt caaaagattg atgacgaaag aaaactactt tcttctatta gtttcctcgg
     3781 caatgcttta gtctctgttt ctagtgatca aactggtgct aagtttgatg gggcaaccat
     3841 gtcaaacaat acgcatgtca gcggagatga tcatatcgat gtaaccaatc caatgaaaga
     3901 cctagccaag ggttacatgt atggatttgt ttctacagat aagcttgctg ctggtgtttg
     3961 gagtaactct caaaacagct atggtggtgg ttcgaatgac tggactcgtt tgacagctta
     4021 taaagaaaca gtcggaaatg ccaactatgt aggaatccac agctctgaat ggcaatggga
     4081 aaaagcttat aagggcattg ttttcccaga atacacgaag gaacttccaa gggctaaggt
     4141 tgttatcact gaagatgcca atgcagacaa gaaagtcgat tggcaggatg gtgccattgc
     4201 ttatcgtagc attatgaaca accctcaagg ttgggaaaaa gttaaggata tcacagctta
     4261 ccgtatcgcg atgaactttg gttctcaagc acaaaaccca ttccttatga ccttggatgg
     4321 tatcaagaaa atcaatctcc acacagatgg tcttgggcaa ggtgttctcc ttaaaggata
     4381 tggtagcgaa ggccatgact ctggtcactt gaactatgct gatattggta agcgtatcgg
     4441 tggtgtcgaa gacttcaaga ccctgattga gaaggctaag aaatatggag ctcatctagg
     4501 tatccacgtt aacgcttcag aaacttatcc tgagtctaaa tacttcaatg aaaaaattct
     4561 ccgtaagaat ccagatggaa gctatagcta tggttggaac tggctagatc aaggtatcaa
     4621 cattgatgct gcctatgacc tagctcatgg tcgtttggca cgttgggaag atttgaagaa
     4681 aaaacttggt gacggtctcg actttatcta tgtggacgtt tggggtaatg gtcaatcagg
     4741 tgataacggt gcctgggcta cccacgttct tgctaaagaa attaacaaac aaggctggcg
     4801 ctttgcgatc gagtggggcc atggtggtga gtacgactct accttccatc actgggcagc
     4861 tgacttgacc tacggtggct acaccaataa aggtatcaac agtgccatca cccgctttat
     4921 ccgtaaccac caaaaagatg cttgggtagg ggactacaga agttatggtg gtgcagccaa
     4981 ctatccactg ctaggtggct acagcatgaa agactttgaa ggctggcaag gaagaagtga
     5041 ctacaatggc tatgtgacta acctctttgc tcatgacgtc atgactaagt acttccaaca
     5101 cttcactgta agtaaatggg aaaatggtac accggtgact atgaccgata acggtagcac
     5161 ctataaatgg actccagaaa tgcgagtgga gttggtagat gctgacaata ataaagtagt
     5221 tgtaactcgt aagtcaaatg atgtcaatag cccacaatat cgcgaacgta cagtaacgct
     5281 caacggacgt gtcatccaag atggttcagc ttacttgact ccttggaact gggatgcaaa
     5341 tggtaagaaa ctttctactg agaaggaaaa gatgtactac ttcaatacgc aggccggtac
     5401 aacaacttgg acccttccaa gcgattgggc aaagagcaag gtttaccttt acaagctaac
     5461 tgaccaaggt aagacagaag agcaagaact aactgtaaaa gatggtaaaa ttaccctaga
     5521 tcttctagca aatcaaccat acgtacttta ccgttcaaaa caaaccaatc ctgaaatgtc
     5581 atggagtgaa ggcatgcaca tctatgacca aggatttaat agtggaacct tgaaacactg
     5641 gaccatttca ggcgatgctt ctaaggcaga aattgtcaag tctcaagggg caaacgatat
     5701 gcttcgtatt caaggaaaca aagaaaaagt tagtctcact cagaaattaa ctggcttgaa
     5761 accaaatacc aagtatgccg tttatgtcgg tgtcgataac cgtagtaatg ccaaggcaag
     5821 tatcactgtg aatactggtg aaaaagaagt gactacttat accaataagt ctctcgccct
     5881 caactatgta aaagcctacg cccacaatac acgtcgtaac aatgctacag ttgacgatac
     5941 aagttacttc caaaacatgt acgccttctt tacaactgga tcggacgtct caaatgttac
     6001 tctgacattg agtcgtgaag ctggtgatca agcaacttac tttgatgaaa ttcgtacctt
     6061 tgaaaacaat tcaagcatgt acggagacaa gcatgataca ggtaaaggca ccttcaagca
     6121 agactttgaa aatgttgctc agggtatctt cccatttgta gtgggtggtg ttgaaggtgt
     6181 tgaagataac cgcactcact tgtctgaaaa acacgatcca tatacacaac gtggttggaa
     6241 tggtaagaaa gtcgatgatg ttatcgaagg aaattggtca ctcaagacaa atggactagt
     6301 gagccgtcgt aacttggttt accaaactat tccgcaaaac ttccgttttg aagcaggtaa
     6361 gacctaccgt gtaacctttg aatacgaagc aggttcagac aatacctatg cttttgtagt
     6421 cggtaaggga gaattccagt caggtcgtcg tggtactcaa gcaagcaact tggaaatgca
     6481 tgaattgcca aatacttgga cagattctaa gaaagccaag aaggtaacct tccttgtgac
     6541 aggtgcagaa acaggggata cttgggtagg tatctactca actggcaatg caagtaatac
     6601 tcgtagtgat tctggtggaa atgccaactt ccgtggttat aacgacttca tgatggataa
     6661 tcttcaaatc gaagaaatta ccctaacagg taagatgttg acagaaaatg ctctgaagaa
     6721 ctacttgcca acggttgcca tgactaacta caccaaagag tctatggatg ctttgaaaga
     6781 ggcggtcttt aacctcagtc aggccgatga tgatatcagt gtggaagaag cgcgtgcaga
     6841 gattgccaag attgaagcct tgaagaatgc tttggttcag aagaaaacgg ctttggtagc
     6901 agaagacttt gcaagtctta cagctcctgc tcaggctcaa gaaggtcttg caaatgcctt
     6961 tgatggaaac ttatctagtt tatggcatac atcatggggc ggaggagatg taggcaagcc
     7021 tgcaaccatg gtcttgaaag aagcaactga aatcactgga cttcgttatg ttccacgtgg
     7081 atcaggttca aatggtaact tgcgtgatgt gaaacttgtt gtgacagatg agtctggcaa
     7141 ggagcatacc tttactgcaa ctgattggcc agataacaat aagccaaaag acattgattt
     7201 tggtaagaca attaaggcta agaaaattgt ccttacaggt actaagactt acggagatgg
     7261 tggcgataaa taccaatctg cagcggaact tatctttact cgtccacagg tagcagaaac
     7321 acctcttgac ttgtcaggct atgaagcagc tttggctaag gctcagaaat taacagacaa
     7381 agacaatcaa gaggaagtag ctagcgttca ggcaagcatg aaatatgcga cggataacca
     7441 tctcttgacg gaaagaatgg tggaatactt tgcagattat ctcaaccaat taaaagattc
     7501 tgctacgaaa ccagatgctc caactgtaga gaaacctgag tttaaactta gctctttagt
     7561 ttccaatcaa ggtaagacgc cagattataa gcaagaaata gatagaccag aaacacctga
     7621 acaaatcttg ccagcaacag gtgagagtca atctgacaca gccctcttcc tagcaagtgt
     7681 tagtctagcc ctatctgctc tctttgtagt aaaaacgaag aaagactagt atttagtaaa
     7741 acctcttaac aagattacgg aagcagtctc tatcttttcc aatgaggttt atagtacaga
     7801 aaaagcctga gaagatgtct tctcaggctt ttgttaagca cataaataca atagtgctat
     7861 gacaaaatca cccagaaaaa tctgggtgat aaatgttatg gttgtgctgg ttgaggattc
     7921 tgattttgtt gatcaggggt tgtatttgat tgttgcgtat tattgttagg attggtagtc
     7981 gtactattat ttgtgcttgg agtggttgag ctagactgtg aagttgaact atctgatgat
     8041 gagcttgaac tttcagttga tgggggttgt tgtggagcag gtgagttcca cgtagaacga
     8101 gcaccatttt taaatacgaa ttctccattt ctgtagagcc cctctggtat attccaatcc
     8161 tctggattgc ttccttcaga cagataggtc atcatagagc ggtaaacttt ggcagcgacc
     8221 gtaagaccat tgcctacaag tggtgtcaga cggttagaat agcctgtcca tacagccatt
     8281 gaatatttac gcgtatagcc agcaaatagt tcatcaggtg ctacaaattg agaggtcttg
     8341 atgtggtttt caatttcctc gtctgtatag ttagaggttc ctgttttacc agcctgaggg
     8401 agccaagcaa gataggcatt tcgtccagtt ccataactca agactgtttt catcatgtcg
     8461 gtcatcatat aggctgtcgt ttccttcatg gcacgagttc cgacattaga gaactctttt
     8521 tcactcccat cactaaagac gactttatgg atatacattg gtttatagta agttccacca
     8581 tttgcaaagg cagcgtaagc agcagccatc ttttcactac ttgctccata ttttttgtct
     8641 gattcggttg tgttacttga aatggcattt gagtagtgaa tacttgggta gtcgattccg
     8701 agaccattta ggaaagtctt ggcgcggttg agtccgacct tgtttagagt ttccacggct
     8761 gggacgtttc gcgattgttg cagggcgtat tgcaaggtga tgttgccaaa gtagccccta
     8821 tcccagttat aaacaggggt atttgtccca gggtagttat agggctcatc gtgaacgata
     8881 gtagcagttg aatcgtagat accgtactcc aaggcaggag catagtctgt gatcggtttc
     8941 atagttgatc cccagtcgcg gtttgtttct actgcttggt taattccgaa ggaaacatta
     9001 cttgactgat ggcgtgctcc tagctgggca atgactttac cgttagaaac atcaacaatg
     9061 gtagaagcga cttgcaattc atcgtctgga taggcaacgt attcgtctgt attgtaaata
     9121 tcccacagat gtttttgagc ttcttggtct acatttgtgt agacatccat cccagttgtg
     9181 agcaggttat agcctgtttc ttcttcaact tgattgatga cttccttgag gtaattatcc
     9241 atgtaagcag ggtaattact tgctgatttg agactttgta gtccatcagt aattggtgta
     9301 ttgactgctt tctcatactg ttcagcagag atgtagcctt gatttttcat ttcagataag
     9361 accaagtttc ggcggtcttg ggctgcttct ggatgtgaat aggggtcata ttggtttggt
     9421 gcctgaggca ttccagccag caaggctaac tgaggtaaac ttaaattatt gaggtcttta
     9481 ccatagtagt tttgagctgc tgtctgcatt ccatagttcc cattagacat gtagacctta
     9541 tttatatagt aggtcaagat ttcttgcttg gttgcttttt gttctaactg aatcgctaac
     9601 caagcttcct gagccttacg agaaatagtc tggtcggaag tcgaagttga aaagtaagtc
     9661 aacttaatca actgttgagt gagagttgat ccaccttgga gggaattgct ttgcagattg
     9721 cgcaagaaag ctcccaggat acggatggta tcaatccccc tgtggtcgaa gaagcgatgg
     9781 tcttcgatag aaacgattgc tttaaccaaa tctgtgggaa tatcattagc ttgggcattg
     9841 acgcggcgtt cagaacccaa gtcagcaatg agttgatttt tattgtcgta gattttacta
     9901 gaagttgttg caactagttt actctcggat aggctaggag ccttgctaac gtagtagaaa
     9961 aaaactcctc cgcctaagac aatggctgcg ataaccaagc ttaagaagct aatgctcaga
    10021 tacttgatta ggcgcagaat cgttggtttg ttcatcttgt tttaccacct aataaatgtt
    10081 ctttgataac attgagataa ggaatttgag ggaaggcacc agccttgatt tcatatccat
    10141 attctcgaat atattcaagt ggcattgatt tttgtccctt atcttgatga tagaagcgaa
    10201 tcaaatcgaa tgccggcaat aagtaggttt cttgctgaga agaaaagtga agaaggacaa
    10261 agcagattcc ttgttgagca aggacttgtt ccatatgctg aatctgatgt ggatgaaaat
    10321 ttttcatcgg aatcgcacgt ttttgttttg tttccttgac ttcaaagtcg atgtaatatc
    10381 cattataaac gccagaatag tccgtcgttg aagcttgtcg aaaataggct tcaacaatct
    10441 tggcacgact tcgttgtgga tagtccactt gtacgatttg aataggagtt ggtttcttat
    10501 gtataacagc caagccctga gacaaatagt agtcgttggt agcattgatc atcttttcaa
    10561 aagacattcc tcgatttgcg aaatttttgg gttgagaaag agatgtttgt cttttttgtg
    10621 atgaaacttt atgtggatag ttgaccataa ttctccttat tggtacaata acatcacttt
    10681 attataccat aatttgcaca gaaagggtta aaaatggcta cagctttggt tttaggctat
    10741 tctgcttttg atttgggttt attttctgat aaggatcctc gtcttaaatt gattaaaaaa
    10801 gcgatacgta aagatttaga ggctatggca gcagatgggg tgtcttggct tgtgtttaca
    10861 gggactttgg gctttgaata ttgggtttta gaggttgctc aggagatgaa aaccgaatac
    10921 ggtttccagt tggccaccat ttttgctttt gaaacccatg gggaaaattg gaatgaaggc
    10981 aatcagatga aactgagtcg ctttaagcag gtagactttg tcaaatatgc ctatcctcgc
    11041 tatgaacaca aggggcagtt aagagattac cagcagtttt tgctggaaaa cacgactagt
    11101 tcctatcttt tttatgatga agaaaatgaa acaaaactag cttattttta ccaaaagatg
    11161 aaaaatcaag aggactattt tataaagaga ttaacatttg atcaattaaa tgaacttgct
    11221 gaaaattttt ccgaaaattg aagctttgac cttgattttt gtttgccttt ttttatataa
    11281 taatactagc aagcgagaat ggagagagac atggcaagta ttattttttc agcgaaagat
    11341 atttttgaac aagagtttgg acgtgaagtc cgtggctata ataaagtaga agttgacgag
    11401 tttttagacg atgtcatcaa ggactatgaa acctatgctg ccttggtcaa gtcacttcgt
    11461 caggaaattg cggatttgaa ggaagaatta actcgtaaac cgaaaccttc accagttcaa
    11521 gcagaacccc ttgaagcggc aattacaagt tctatgacga attttgatat tttgaaacgc
    11581 ctgaatagat tggaaaaaga agtttttggt aaacaaattt tagataactc agatttttaa
    11641 gtagttattt gagatgtgca atttttggat aatcgcgtga ggagaattgc ttctcatgag
    11701 gaaagtccat gctagcacag gctgtgatgc ctgtagtgtt tgtgctaggc gaaaccataa
    11761 gcctagggac gagaaatcgt tacggcagtt gaaatggcta agtccttgga taggccagag
    11821 taggcttgaa agtgccacag tgacgaagtc tttctggaaa cagagagagt ggaacgcggt
    11881 aaacccctca agctagcaac ccaaattttg gtcggggcat ggagtacgcg gaaacgaacg
    11941 tagtattctg actgctatca gctagagctg ttagtggtag acagatgatt atcgaaggaa
    12001 gtggtcctag tcacttctgg aacaaaacat ggcttataga aaattgcata taggttgggg
    12061 ctgagaaatt ttctcaacct cattttttaa agtggacata tagaaaggtc ttgcaagact
    12121 gtaacatgaa aaaagaattt aatttaattg caactgtggc agcagggctt gaggctgtcg
    12181 ttggtcgtga agtgcgagag ttgggctacg attgtcagat tgaaaatgga cgtgttcgtt
    12241 ttcaaggaga cgtgagagct attatcgaaa ccaacctttg gctgcgggca gcagatcgta
    12301 tcaaaattat cgtaggaacg ttccctgcta agacttttga agagctattt cagggagttt
    12361 tcgctttaga ttgggaaaat tatttaccac ttggagctcg gttcccgatt tcaaaagcta
    12421 aatgtgttaa gtccaaactt cacaatgagc ccagtgttca ggctatttct aagaaagctg
    12481 ttgtcaagaa attgcagaaa cactatgctc gcccagaagg ggttcctctg atggagaatg
    12541 gcccagagtt taagattgag gtctctattc tcaaagatgt ggcaactgtc atgattgata
    12601 cgaccgggtc tagcctcttt aaacgtggtt atcgtaccga aaaaggtggc gctcctatca
    12661 aggaaaatat ggcagcagcc attttacaac tttctaactg gtatccagac aagcctttga
    12721 ttgatccgac ctgtggttcg gggactttct gtattgaggc agttatgatt gctagaaaga
    12781 tggcgtcagg tcttcgtcgc tcttttgcat ttgaggaatg gaactggatc agcgatcgct
    12841 tgattcaaga agtgcgcaca gaagcggcta aaaaagtaga ccgtgagctt gagctggata
    12901 tcatgggctg tgatattgat gctcgcatgg tggaaattgc taaggccaat gctcaggcag
    12961 ctggtgttgc aggagacatt acttttaagc agatgcgcgt gcaggattta tgttccgata
    13021 aaatcaatgg agtaatcatt tccaatccgc cttatggtga acgtttgtca gatgatgcag
    13081 gggtgaccaa gctctatgct gagatggggc aagtatttgc accgctgaaa acttggagca
    13141 aatttatcct gactagtgat gaagcttttg aaagcaagta tggtagccaa gcagataaga
    13201 agcgtaagtt atacaacgga accttgaaag tggatctgta tcaatatttt ggtcagcgtg
    13261 tcaaacggca agaggtaaaa tagaaaggga tactcatgag taaaaaaaga cgaaatcgtc
    13321 aaaaaaaaga aggtcaagaa ccgcaatttg attttgatga agcaaaagag ctaacagttg
    13381 gtcaagctat tcgtaaaaat gaagaagtgg aagcaggagt cttgcctgag gattccattt
    13441 tggacaagta tgttaagcaa cacagagatg aaattgaggc ggataagttt gcgactcgtc
    13501 aatacaaaaa agaggagttc gttgaaactc agagtctgga tgatttaatt caagagatgc
    13561 gtgaggctgt agagaagtca gaagcttctt cggaggaagt tccatcttct gaagacatct
    13621 tactaccctt gcctctggac gatgaggagc aaggcttgga tcctctattg ctagatgatg
    13681 aaaatccaac agaaatgact gaagaagtgg aagaggagca aaacctttct cgtctggatc
    13741 aagaggactc agaaaagaaa agtaaaaaag gctttatttt gaccgttttg gcgcttgtat
    13801 cagtaattat ttgtgtcagt gcttattatg tctaccgtca agtggctcgt tcgaccaagg
    13861 aaattgaaac ttctcaatca actacagcca atcaatcgga tgtggatgat tttaatacac
    13921 tttatgacgc cttttacaca gatagcaata aaacggcttt gaaaaatagc cagtttgata
    13981 aactgaatca actcaagact ttacttgata agctggaagg tagtcgtgaa catacgcttg
    14041 ccaaatctaa atatgatagt ctagcaacgc aaatcaaggc tattcaagat gtcaatgctc
    14101 aatttgagaa accagctatt gtggatggtg tgttggatac caatgccaaa gccaaatcgg
    14161 atgctaaatt tacggatatt aaaactggaa atacggagct tgataaagtg ctagataagg
    14221 ctatcagtct tggtaagagc cagcaaacaa gtacttctag ctcaagttca agtcaaacta
    14281 gcagctcaag ttcaagtcaa gcaagttcaa atacgactag tgagccaaaa ccaagtagtt
    14341 caaatgagac tagaagtagt cgcagtgaag tcaatatggg tctctcgagt gcaggggttg
    14401 ctgttcaaag aagtgccagt cgtgttgcct ataatcagtc tgctattgat gatagtaata
    14461 actctgcctg ggattttgcg gatggtgtct tggaacaaat tctagcgact tcacgttcac
    14521 gtggctatat cactggagac caatatatcc ttgaacgtgt caatatcgtt aacggcaatg
    14581 gttattacaa cctctataag ccagatggaa cctatctctt tacccttaac tgtaagacag
    14641 gctactttgt cggaaatggc gctggtcatg cggatgactt ggactactaa gcagtcgtta
    14701 caaaattctt tcttttcaaa agtaaaaatg ataaaataaa acaaatgaaa caagaggagt
    14761 gtcaaatgac aaaagctaac tttggtgtcg taggtatggc cgtaatgggt cgtaaccttg
    14821 cccttaatat tgaatcacgt ggttacacag ttgctatcta caaccgtagt aaagaaaaaa
    14881 cggaagatgt gattgcttgc catcctgaaa agaattttgt accaagctat gacgttgaaa
    14941 gttttgtaaa ctcaatcgaa aaacctcgtc gtatcatgct gatggttcaa gctggacctg
    15001 gtacagatgc tactatccaa gcccttcttc cacaccttga caagggtgat atcttgattg
    15061 acggaggaaa cactttctac aaagatacca tccgtcgtaa tgaagaattg gcaaactcag
    15121 gtatcaactt tatcggtact ggagtttctg gtggtgaaaa aggtgccctt gaaggtcctt
    15181 ctatcatgcc tggtggacaa aaagaggcct acgaattggt tgcggatgtt cttgaagaaa
    15241 tctcagctaa agcaccagaa gatggcaaac catgtgtgac ttacatcggc cctgatggag
    15301 ctggtcacta tgtgaaaatg gttcacaatg gtattgagta cggtgatatg caattgatcg
    15361 cagaaagcta tgacttgatg caacacttgc taggcctttc tgcagaggat atggctgaaa
    15421 tctttactga gtggaacaag ggtgaattag acagctattt gatcgaaatc acagctgata
    15481 tcttgagcca taaagacgat gaaggccaag atggaccaat cgtagactac atccttgatg
    15541 ctgcaggtaa caagggaact ggtaaatgga ctagccaatc atctcttgac cttggtgtac
    15601 cattgtcact gattactgag tcagtgtttg cacgctacat ttcaacttac aaagaagaac
    15661 gtgtatatgc tagcaaggtg cttccaaaac cagctgcctt caactttgaa ggagacaagg
    15721 ctgaattgat tgaaaagatc cgtcaagccc tttacttctc aaaaatcatt tcatacgcac
    15781 aaggatttgc tcaattgcgt gtagcctcta aagaaaacaa ctggaacttg ccatttgcag
    15841 atatcgcatc tatctggcgt gatggctgta tcatccgttc tcgtttcttg caaaagatta
    15901 cagatgctta caaccgcgat gcagatcttg ccaaccttct tttggacgag tacttcttgg
    15961 atgttactgc taagtatcaa caagcagtgc gtgatatcgt agctcttgcg gttcaagctg
    16021 gtgtgccagt gccaactttc tcagcagcta ttacttactt tgatagctac cgttcagctg
    16081 accttccagc taacttgatc caagcacaac gtgactactt tggtgctcac acttaccaac
    16141 gtaaagacaa agaaggaacc ttccactact cttggtatga cgaaaaataa gtaggtcagc
    16201 catggggaaa cggattttat tacttgagaa agaacgaaat ctagctcatt ttttaagttt
    16261 ggaactccag aaagagcagt atcgggttga tctggtagag gaggggcaaa aagccctctc
    16321 catggctctt cagacagact atgatttgat gttattgaac gttaatctgg gagatatgat
    16381 ggctcaggat tttgcagaaa aattgagtcg aactaaacct gcctcagtca tcatgatttt
    16441 agatcattgg gaagacttgc aagaagagct ggaagttgtt cagcgttttg cagttgcata
    16501 catttataag ccagtcctta tcgaaaatct ggtagcgcgt atttcggcga tcttccgagg
    16561 tcgggacttc attgatcaac actgcagtct gatgaaagtt ccaaggactt accgcaatct
    16621 taggatagat gttgaacatc acacggttta tcgtggtgaa gagatgattg ctctgacccg
    16681 ccgtgagtat gaccttttgg cgacacttat gggaagcaag aaagtattga ctcgtgagca
    16741 attgttggaa agtgtttgga agtatgaaag tgcgaccgag acaaatatcg tagatgtcta
    16801 tatccgctat ctacggagca agcttgatgt taaaggccaa aaaagctaca ttaaaaccgt
    16861 gcgtggtgtt ggatatacca tgcaagaata gataagcagt tgcagttgtg taactgcttt
    16921 tttgaggagt ttttatatat tgacatgcag tcgggtcttt gctacaatcg ttttaggagg
    16981 atatatagat gaaacttttg aaaaaaatga tgcaagttct actagcagtc tttttctttg
    17041 gtttgctagc tacaaatacg gtatttgcga ataccacagg tggccaattt gttgataagg
    17101 ataatagaaa atattatgta aaagatgatc ataaagcaat ctattggcat aaaatagacg
    17161 gtaaaactta ctattttggt gatattggag agatggttgt cggttggcaa tacttagaaa
    17221 ttcctggaac aggttatcgt gataatttat tcgataacca accagttaat gagattggcc
    17281 ttcaggagaa gtggtactat tttggacaag atggtgcttt gctagaacaa acagataaac
    17341 aagtactaga gccaaaaacg tctgaaaata caggaaaagt atacggtgaa caatatcctc
    17401 tatctgctga aaagagaact tattattttg ataataatta tgctgtaaag acaggctgga
    17461 tttatgaaga cggcaattgg tattatttaa ataagctagg aaattttggc gatgattctt
    17521 acaatccact accaattggt gaagttgcta agggttggac tcaagatttt catgttacta
    17581 ttgacattga tagaagcaaa cctgctccat ggtactacct agatgcttca ggtaagatgc
    17641 ttacagattg gcaaaaagta aacggaaaat ggtattattt tggctcctct ggttctatgg
    17701 caacaggttg gaaatatgta cgaggcaaat ggtattactt agataataaa aatggtgata
    17761 tgaaaacagg atggcaatac tttggtaaca agtggtacta cctccgttca tcaggagcta
    17821 tggtaactgg ctggtatcaa gatggtttaa cttggtacta cctaaatgca ggtaatggag
    17881 acatgacgac aggttggttc caggtcaatg gcagatggta ctacgcttat agctcaggtg
    17941 ccttggcagt gaatacgacc gtagatggct attctgtcaa ctataatggc gaatgggttc
    18001 aataatgaaa gaagcgattg tgaatggaaa caatcgcttt ttttgtgaaa atataataaa
    18061 atagatagga aagaattaat acttgtatga aaaataagac gttttttcgt ctagtaaaag
    18121 gaaaaaatga caaaaaaagt tggtgtcggt caggcacata gtaagataat tttaataggg
    18181 gaacatgcgg tcgtttacgg ttatcctgcc atttccctgc ctcttttgga ggtggaggtg
    18241 acctgtaagg tagttcctgc agagagtcct tggcgccttt atgaggagga taccttgtcc
    18301 atggcggttt atgcctcact ggagtatttg aatatcacag aagcctgcat tcgttgtgag
    18361 attgactcgg ctatccctga gaaacggggg atgggttcgt cagcggctat cagcatagcg
    18421 gccattcgtg cagtatttga ctactatcag gctgatctgc ctcatgatgt actagaaatc
    18481 ttggtcaatc gagctgaaat gattgcccat atgaatccta gtggtttgga tgctaagacc
    18541 tgtcttagtg accaacctat tcgctttatc aagaacgtag gatttacaga acttgagatg
    18601 gatttatccg cctatttggt gattgccgat acgggtgttt atggtcatac tcgtgaagcc
    18661 atccaagtgg ttcaaaataa gggcaaggat gccctaccgt ttttgcatgc cttgggagaa
    18721 ttaacccagc aagcagaagt tgcgatttca caaaaagatg ctgaaggact gggacaaatc
    18781 ctcagtcaag cgcatttaca tttaaaagaa attggagtca gtagccctga ggcagacttt
    18841 tgggttgaaa cgactcttag ccatggtgct ctgggtgcca agatgagcgg tggtgggcta
    18901 ggaggttgta tcatagcctt ggtaaccaat ttgacacacg cacaagaact agcagaaaga
    18961 ttagaagaga aaggagctgt tcagacatgg atagagagcc tgtaacagta cgttcctacg
    19021 caaatattgc tattatcaaa tattggggaa agaaaaaaga aaaagagatg gtgcctgcta
    19081 ctagcagtat ttctctaact ttggaaaata tgtatacaga gacgaccttg tcgcctttac
    19141 cagccaatgt aacagctgac gaattttaca tcaatggtca gctacaaaat gaggtcgagc
    19201 atgccaagat gagtaagatt attgaccgtt atcgtccagc tggtgagggc tttgtccgta
    19261 tcgatactca aaacaatatg cctacggcag cgggtctgtc ctcaagttct agtggtttgt
    19321 ccgccctggt caaggcttgt aatgcttatt tcaagcttgg attggataga agtcagttgg
    19381 cacaggaagc caaatttgcc tcaggttctt cttctcggag tttttatgga ccactaggag
    19441 cctgggataa ggatagtgga gaaatttacc ctgtagagac agacttgaaa ctagctatga
    19501 ttatgttggt gctagaggac aagaaaaaac caatctctag ccgtgacggg atgaaacttt
    19561 gtgtggaaac ctcgacgact tttgacgact gggttcgtca gtctgagaag gactatcagg
    19621 atatgctgat ttatctcaag gaaaatgatt ttgccaagat tggagaatta acggagaaaa
    19681 atgccctggc tatgcatgct acgacaaaga ctgctagtcc agccttttct tatctgacgg
    19741 atgcctctta tgaggctatg gactttgttc gccagcttcg tgagaaagga gaggcctgct
    19801 actttaccat ggatgctggt cccaatgtta aggtcttctg tcaggagaaa gacttggagc
    19861 atttatcaga aattttcggt catcgttatc gcttgattgt gtcaaaaaca aaggatttga
    19921 gtcaagatga ttgctgttaa aacttgcgga aaactctatt gggcaggtga atatgctatt
    19981 ttagagccag ggcagttagc tttgataaag gatattccca tctatatgag ggctgagatt
    20041 gctttttctg acagctaccg tatctattca gatatgtttg atttcgcagt ggacttaagg
    20101 cctaatcctg actacagctt gattcaagaa acgattgctt tgatgggaga cttcctcgct
    20161 gttcgcggtc agaatttaag acctttttcc ctaaaaatct gtggcaaaat ggaacgagaa
    20221 gggaaaaagt ttggtctagg ttctagtggc agcgtcgttg tcttggttgt caaggcttta
    20281 ttggctctct ataatctttc ggttgatcag gagctcttgt tcaagctgac tagcgctgtc
    20341 ttgcttaagc gaggagacaa tggttccatg ggcgaccttg cctgtattgt ggcagaggat
    20401 ttggttctct accagtcatt tgatcgccag aaggcggctg cttggttaga agaagaaaac
    20461 ttggcgacag ttctggagcg tgattgggga ttttttatct cacaagtgaa accaacttta
    20521 gaatgtgatt tcttagtggg atggaccaag gaagtggctg tatcgagtca catggtccag
    20581 caaatcaagc aaaatatcaa tcaaaatttt ttaagttcct caaaagaaac ggtggtttct
    20641 ttggtcgaag ccttggagca ggggaaagcc gaaaaagtta tcgagcaagt agaagtagcc
    20701 agcaagcttt tagaaggctt gagtacagat atttacacgc ctttgcttag acagttgaaa
    20761 gaagccagtc aagatttgca ggccgttgcc aagagtagtg gtgctggtgg tggtgactgt
    20821 ggcatcgccc tgagttttga tgcgcaatca accaaaacct taaaaaatcg ttgggccgat
    20881 ctggggattg agctcttata tcaagaaagg ataggacatg acgacaaatc gtaaggacga
    20941 gcatatcctc tatgcccttg agcagaaaag ttcctataat agctttgatg aggtggagct
    21001 gattcattct tccttgcctc tttacaatct ggatgaaatc gatctttcga cagagtttgc
    21061 tggtcgaaag tgggactttc ctttttatat caatgccatg actggtggaa gtaataaggg
    21121 aagagaaatc aatcaaaagc tggctcaggt ggcggaatcc tgtggtattt tatttgtaac
    21181 gggttcttat agcgcagccc tcaaaaatcc aacggataat tctttttctg tcaagtctag
    21241 tcatcccaat ctcctccttg gaaccaatat tggattggac aaacctgtcg agttaggact
    21301 tcagactgta gaagagatga atcctgttct attgcaagtg catgtcaatg tcatgcagga
    21361 attactcatg cccgagggag aaaggaagtt tagaagctgg caatcgcatc tagcagatta
    21421 tagcaagcaa attcccgttc ctattgtcct caaggaagtg ggctttggaa tggatgccaa
    21481 gacaatcgaa agagcctatg aattcggtgt tcgtacagtg gacctatcgg gtcgtggtgg
    21541 caccagcttt gcctatatcg aaaaccgtcg tagtggccag cgtgattacc tcaatcaatg
    21601 gggtcagtct accatgcagg cccttctcaa tgcccaagaa tggaaagata aggtcgaact
    21661 cttggttagt ggaggggttc ggaatccgct ggatatgatt aagtgcttgg tttttggtgc
    21721 taagtctgtg ggattgtcac gaaccgttct ggaattggtt gaaacctaca cagttgaaga
    21781 agtgattggc attgtccaag gctggaaagc agacctacgc ttgattatgt gttcccttaa
    21841 ctgtgccacc atagcagatc tacaaaaagt agactatctt ctttatggaa aattaaaaga
    21901 agcaaatgat cagatgaaaa aggcgtaacc agcgcctttt ttccatcctc agactgaggt
    21961 gacttttttg aattgtgata aaatagaagg gagaggatga acctatgaga aaatttaaaa
    22021 tctttttatt tatcgaagcc tgtcttctga caggagctct gattttgatg gtatcagagc
    22081 atttttcgcg ttttctgctg atactattcc tctttttgct tttgattcgc tactacactg
    22141 gtaaagaggg gaataatctt cttttagtag cggcaaccat tctcttcttt ttcattgtta
    22201 tgctcaatcc ttttgtgatt ctagctattt ttgttgcggt tatctatagt ctctttcttc
    22261 tttacccgat gatgaaccag gaaaaagagc agaccaattt ggtttttgaa gaggttgtga
    22321 cggttaagaa ggagaaaaat cgttggtttg gaaatcttca tcatttttca agctaccaga
    22381 cttgccaatt tgatgatatc aatctctttc gcttcatggg caaggacact attcatctgg
    22441 agagagtcat cttaaccaat catgacaatg tcattatcct cagaaagatg gtaggaacga
    22501 ccaaaatcat cgtacctgta gatgtggaag tcagtctcag cgttaactgt ctctatgggg
    22561 atttgacttt tttcaaccag cccaagcgag ccctccgcaa tgaacactat catcaagaaa
    22621 caaaagacta tctcaagagt aacaagagtg tcaagatttt cttgaccact atgattggtg
    22681 atgttgaggt ggttagagga tgaaaaaaca agcctatgtc attatcgctc tcacctcctt
    22741 cctgtttgtc ttttttttct cccatagctt gctggaaata cttgattttg actggtctat
    22801 ctttttgcac gatgtcgaaa aaacagaaaa atttttcttt ttattgttgg ttttcagcat
    22861 gtccatgacc tgtctcttag ccctgttttg gcgagggatc gaagagcttt ctctaagaaa
    22921 aatgcaggct aatctcaagc gtttattggc agggcaagaa gtggttcagg ttgtagatcc
    22981 agatttggat gccagtttca agtccttatc aggtaaactt aaccttttga cagaggctct
    23041 tcaaaaagct gaaaatcata gccttgctca ggaagaggaa atcatcgaga aggaacggaa
    23101 gcgaattgct cgggatttgc acgatacagt cagtcaggag ttgtttgcgg cccacatgat
    23161 tttatcgggt atcagtcagc aggctttgaa attggataga gaaaagatgc agacccagtt
    23221 gcagagtgtc acagctattt tagaaacagc ccagaaggat ttgcgggttt tgctcttgca
    23281 tttgcgacca gttgaactgg agcagaagag cttgatagaa gggattcaaa ttcttttaaa
    23341 agagcttgag gacaagagtg atcttagggt tagtctcaag cagaatatga cgaaattgcc
    23401 taagaaaatc gaggagcata tcttccgtat cctgcaagag ttgattagca ataccctccg
    23461 ccatgcccag gcatcttgcc tagatgtcta cctctatcag acagatgttg aattgcaact
    23521 gaaggtggtg gacaatggga ttggtttcca gttagggagc ttagacgact tgagttatgg
    23581 actgcgaaat atcaaggagc gggttgaaga tatggctgga acagttcaac tcttgacagc
    23641 tcccaagcaa gggctggcgg ttgatatccg tattcctctg ttagataagg aatgataaag
    23701 gagtaaagat gaaaatttta ctagtagatg accatgaaat ggtccgattg ggcttgaaaa
    23761 gctactttga cctccaagac gatgtagaag ttgtgggtga ggcgtccaac gggtctcaag
    23821 ggattgactt ggccttggaa ctgcgtccag atgtcattgt catggatatt gtcatgcctg
    23881 agatgaatgg gattgacgcg accttagcaa tccttaaaga atggcctgaa gccaagattt
    23941 tgattgtgac ctcttatttg gacaatgaaa aaatcatgcc agtcttagat gctggtgcca
    24001 aaggctatat gctcaagact tctagtgcag atgaattgct tcatgccgtc agtaaggtag
    24061 ctgctggcga gctggccatt gagcaagagg ttagcaagaa ggttgaatac caccgcaatc
    24121 atatggaact tcatgaagaa ttgactgcgc gtgagcgaga tgttctccaa ctcatcgcca
    24181 agggctacga aaatcagcgc atcgcagatg acctctttat ctctctcaag acggtcaaga
    24241 cccacgtgtc caatattctt gccaaacttg aagtcagcga tcgtacccag gcggctgtct
    24301 atgcctttca gcaccatttg gtggggcaag aggagtttta gatgagttta gcagatttac
    24361 ttgaggagct agaagcagca aaagactcta aaaaagcaag gtccatggaa gcctatatgc
    24421 gccatcaatt ttcttttcta ggtattgcgg tgcctgaaag aaataaactc tataaaatat
    24481 tttccagaag cgaaaaaaac aaagattatc gattgggatt ttgcagacac ttgctgggaa
    24541 aagaatccta gaaaatacca atatgtggct gctaactatt tgaaagcaat gcagtcttat
    24601 ctaaaggaaa ccgatttgcc taagctagag cagttagtcg tgacaaaatc ctggtgggac
    24661 acggtagata tcctagatcg agtagtaggg agtttggtgt atgaacactc tgaactagaa
    24721 gaaataatct taatactctt cgaaaatctc ttcaaaccac gtcagctcta tctgcaacct
    24781 caaaacagtg ttttgagcaa tctgcggcta gcttcctagt ttgctctttg attttcattg
    24841 agtataaaat ggagcctatc agataatatc tggctgagac gtgtcgctat tgaccaccag
    24901 ttgttaagaa aagagaagac caatactcaa ttaatggaaa agattctact tcataacttg
    24961 aaccaaacag aattttttat caataaagcc attggctgga ctctgcgaga ctactccaaa
    25021 acgaatccca cttgggtaac atgctttatt gagaaaaaca aggaaagaat ggctgaactt
    25081 agtatcaaag aagcaagcaa gtacctctag cgtgattgaa aagcgcagtc attaattgaa
    25141 aagtttacct gtttatgtga taatggaggg tatttaaaga aggtggtaga tttcttgatt
    25201 ctatagtaga ttaagaaatt tagaatagta cgctataatt acattaggag gatacaataa
    25261 tgaagaaaac tgtttataaa aaattgggta tttcaattat tgcgagtact ttattggcta
    25321 gccagttatc gacagtatct gctttgagtg ttatttctag tacaggtgaa gaatatgagg
    25381 taagtgagac actagaaaaa ggtccagagt ctaatgattc ttcattatct gagatttcac
    25441 caacgtatgg ttcatactac caaaagcaat cagaagtatt atcggtaatg atgatttgat
    25501 taaaattgat aatactttac agtatccgta ttcgacttca gctatggttt tatctaagta
    25561 ttatggagta gccgatggaa tgaatgtaga agggagggga agtgcgaatt ttattaaaga
    25621 taatgtgtta attacagcgg ctcacaacta ctacagacat gactatggga aagaagcgga
    25681 tgatatttat gttcttccgg ctgttagtcc aagtcaagaa ctatttggaa agatcaaagt
    25741 aaaggaagtt cgttatttga aggaatttag aaatttaaat tctaaggatg caagggaata
    25801 tgacttggct ttattaattc tagaagagcc cattggtgca aaattaggga ctttgggtct
    25861 tcctactagt caaaaaaatt tgacaggaat aactgtgact atcacaggct atccatcata
    25921 taattttaaa attcatcaaa tgtatacaga taaaaaacaa gttttaagtg atgatggcat
    25981 gttcttggat taccaagttg atactttaga ggggtctagt ggatctacag tttatgatgc
    26041 tagtcaccgt gtagtaggag tgcatacttt aggagatgga gctaatcaaa ttaacagtgc
    26101 agttaaatta aatgaacgaa atttgccatt tatttattcg gttcttaaag gttactctct
    26161 tgaaggatgg aagaaaataa atggtagttg gtaccattat agacaacatg ataaacaaac
    26221 gggttggcag gagataaatg atacttggta ttatttagac agttccggta agatgcttac
    26281 agattggcaa aaagtaaatg gaaaatggta ttatctcaat tcaaatggag caatggttac
    26341 aggtagccaa actatcgatg gtaaagttta taacttcgct tcatctggtg agtggattta
    26401 atgttggagg atatataaaa tgaagctttt gaaaaaaatg atgcaaatcg cactagccac
    26461 atttttcttc ggtttgttag cgacaaatac agtatttgca gatgattctg aaggatggca
    26521 gtttgtccaa gaaaatggta gaacctacta caaaaagggg gatctaaaag aaacctactg
    26581 gagagtgata gatgggaagt actattattt tgatccttta tccggagaga tggttgtcgg
    26641 ctggcaatat atacctgctc cacacaaggg ggttacgatt ggtccttctc caagaataga
    26701 gattgctctt agaccagatt ggttttattt tggtcaagat ggtgtattac aagaatttgt
    26761 tggcaagcaa gttttagaag caaaaactgc tacgaatacc aacaaacatc atggggaaga
    26821 atatgatagc caagcagaga aacgagtcta ttattttgaa gatcagcgta gttatcatac
    26881 tttaaaaact ggttggattt atgaagaggg tcattggtat tatttacaga aggatggtgg
    26941 ctttgattcg cgcatcaaca gattgacggt tggagagcta gcacgtggtt gggttaagga
    27001 ttaccctctt acgtatgatg aagagaagct aaaagcagct ccatggtact atctaaatcc
    27061 agcaactggc attatgcaaa caggttggca atatctaggt aatagatggt actacctcca
    27121 ttcgtcagga gctatggcaa ctggctggta taaggaaggc tcaacttggt actatctaga
    27181 tgctgaaaat ggtgatatga gaactggctg gcaaaacctt gggaacaaat ggtactatct
    27241 ccgttcatca ggagctatgg caactggttg gtatcaggaa agttcgactt ggtactatct
    27301 aaatgcaagt aatggagata tgaaaacagg ctggttccaa gtcaatggta actggtacta
    27361 tgcctatgat tcaggtgctt tagctattaa taccacagta ggtggttact atttaaacta
    27421 taatggtgaa tgggttaagt aatgaagact aattgtaaac tgtgatggat acttaacttt
    27481 gtataatagg tggataaaag tcttcacaat caaaaaacgc atagtatcaa ggtttttctg
//
LOCUS       DAVHKZ010000030        24983 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000030 DAVHKZ010000000
VERSION     DAVHKZ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24983
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.030"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(305..592)
                     /locus_tag="VVO74_001534"
     CDS             complement(305..592)
                     /locus_tag="VVO74_001534"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU5695539.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            901..1173
                     /locus_tag="VVO74_001535"
                     /pseudo
     CDS             901..1173
                     /locus_tag="VVO74_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1284..1487)
                     /locus_tag="VVO74_001536"
     CDS             complement(1284..1487)
                     /locus_tag="VVO74_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU5695540.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(1518..2126)
                     /locus_tag="VVO74_001537"
     CDS             complement(1518..2126)
                     /locus_tag="VVO74_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU5695541.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(2165..2335)
                     /locus_tag="VVO74_001538"
     CDS             complement(2165..2335)
                     /locus_tag="VVO74_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU5695542.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(2347..2913)
                     /gene="amaP"
                     /locus_tag="VVO74_001539"
     CDS             complement(2347..2913)
                     /gene="amaP"
                     /locus_tag="VVO74_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU5695543.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSNLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(2997..3161)
                     /locus_tag="VVO74_001540"
     CDS             complement(2997..3161)
                     /locus_tag="VVO74_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU5695544.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            3604..5085
                     /locus_tag="VVO74_001541"
     CDS             3604..5085
                     /locus_tag="VVO74_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU5695545.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            5447..6448
                     /locus_tag="VVO74_001542"
     CDS             5447..6448
                     /locus_tag="VVO74_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU5695546.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            6599..7516
                     /locus_tag="VVO74_001543"
     CDS             6599..7516
                     /locus_tag="VVO74_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU5695547.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            7527..8417
                     /locus_tag="VVO74_001544"
     CDS             7527..8417
                     /locus_tag="VVO74_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU5695548.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            8446..10062
                     /locus_tag="VVO74_001545"
     CDS             8446..10062
                     /locus_tag="VVO74_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU5695549.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVENLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            10072..11391
                     /locus_tag="VVO74_001546"
     CDS             10072..11391
                     /locus_tag="VVO74_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU5695550.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKIEQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(11601..11673)
                     /locus_tag="VVO74_001547"
     tRNA            complement(11601..11673)
                     /locus_tag="VVO74_001547"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11638..11640),aa:Lys,seq:ctt)
     gene            complement(11938..13209)
                     /locus_tag="VVO74_001548"
     CDS             complement(11938..13209)
                     /locus_tag="VVO74_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU5695551.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELENAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            13479..13679
                     /locus_tag="VVO74_001549"
     CDS             13479..13679
                     /locus_tag="VVO74_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695552.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            13883..14062
                     /locus_tag="VVO74_001550"
     CDS             13883..14062
                     /locus_tag="VVO74_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695553.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            14199..14378
                     /locus_tag="VVO74_001551"
     CDS             14199..14378
                     /locus_tag="VVO74_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU5695554.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            14415..14867
                     /locus_tag="VVO74_001552"
     CDS             14415..14867
                     /locus_tag="VVO74_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU5695555.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            15158..15628
                     /locus_tag="VVO74_001553"
     CDS             15158..15628
                     /locus_tag="VVO74_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU5695556.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFIMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            15684..16226
                     /locus_tag="VVO74_001554"
     CDS             15684..16226
                     /locus_tag="VVO74_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695557.1"
                     /translation="MLEKVKQFFRSRSAKTEPSVDILPRNRFEDLDFERVLKSGARRL
                     VNEEGRYAEDGKITELEFPEDFAEFEFLVGFKTEEEEQFQQLLARLNSIDNAIQSYLE
                     SEMQQPIPQYAKDLGYTQKRWEKTFYFHPWILSGEENPPNLRYVADYVNDEFTVYFAK
                     KHGRWQAYWDAECQKVIEES"
     gene            16276..16440
                     /locus_tag="VVO74_001555"
     CDS             16276..16440
                     /locus_tag="VVO74_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="HEU5695558.1"
                     /translation="MELLNSRMDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPG
                     GGKSVRENLI"
     gene            16550..17584
                     /locus_tag="VVO74_001556"
     CDS             16550..17584
                     /locus_tag="VVO74_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU5695559.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGISK
                     SSVSRELSED"
     gene            17586..19829
                     /locus_tag="VVO74_001557"
     CDS             17586..19829
                     /locus_tag="VVO74_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008288790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HEU5695560.1"
                     /translation="MNTLLTLRGKSFTPKSAKGRGPITIPADSIVTLNHLNELYTSLE
                     RVKEYWSNNTIIDGVLISVYYNRVLAKSNRIDGFFNVGGGNAIPNETIVGAKFSNDKS
                     RHIITHYISKEVLDKTIEHTKKVITIFKDYFASAPMTSMVFSDSSKFNQIDYSKYGLS
                     KSKFKQYLRDACFVKGFGIEQADMSTIRNSIVTIYDVKTNLLTLLKQLDIDVSEANIM
                     DQTTVLLDEKNIELLLLKAPYLVSMIVEDFSSLSPENFYNDGNTFYNNLPFPTNEPII
                     GVIDTLFDDRVYFNEWVEYHDLISPDISKGSQDYKHGTAVSSVIVDGASLNPKLDDGC
                     GRFRVRHFGISLQSGFNSFTIIKQIREIVSQNPDIKVWNLSLGSNDEIRENFISVEGS
                     LLDEIQFDNDVIFIIAGTNGIAPDGQRKKIGAPADSLNSIIVNSVDFSNQVVSYSREG
                     VVLSFFIKPDVSYYGGGNGDFINVCEPLGLARVAGTSFAAPFIARKMAYLIHIMGLSR
                     EEAKALLIDSAIPWNDKKTFADISLLGYGVVPIKIEDILSTPDDEIKFIVSDVSRAYE
                     TYNYDFPVPISKEHYPYVAKATMCYFPKCSRNQGVDYTNTEMQLSLGVLDKKGIKTIN
                     NDNQYSENAPGYVREKSARNIFRKWDNVKHLGEKFSSRKKAKPILNPSNPQWGMSVKT
                     IERLRNDDGYGIRFGVVVTLKELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSL
                     NEEIEFE"
     gene            19880..20899
                     /locus_tag="VVO74_001558"
     CDS             19880..20899
                     /locus_tag="VVO74_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU5695561.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYKDFYEFQNRTYISRKENEEEYSN
                     LIYESLFSDTVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEIVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDNMRTSLPVINQPAIDKKYNENLYQHDIVNILTLNYT
                     NVIDKLYNESAKSFSNQLRTNNYKFHIAPPIHAHGTVDICTVLGVSDETQISNSFDEE
                     QKESLIKNLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDGYIWNQIAEQSIRSS
                     VPVIIYHYVPHFDAGNPTRVKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIF
                     NLMER"
     gene            20912..21862
                     /locus_tag="VVO74_001559"
     CDS             20912..21862
                     /locus_tag="VVO74_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU5695562.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQACLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     IFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVVAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            21864..22607
                     /locus_tag="VVO74_001560"
     CDS             21864..22607
                     /locus_tag="VVO74_001560"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU5695563.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            22618..24414
                     /gene="pepF"
                     /locus_tag="VVO74_001561"
     CDS             22618..24414
                     /gene="pepF"
                     /locus_tag="VVO74_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU5695564.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETA
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(24474..24746)
                     /locus_tag="VVO74_001562"
                     /pseudo
     CDS             complement(24474..24746)
                     /locus_tag="VVO74_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            24734..24916
                     /locus_tag="VVO74_001563"
                     /pseudo
     CDS             24734..24916
                     /locus_tag="VVO74_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
BASE COUNT         8025 a         4206 c         5046 g         7706 t
ORIGIN      
        1 ttatataatt tatttcatat tttgtaaggt cagtgtgaaa atatttaaat agacttcctg
       61 taaaaactgg atttaacgcc ctccatttgt caaattaagc tagacagtct taccaactca
      121 gaaaatacct gatgaggtat ttggtatcca aaggatttag gtgggatgtg atttcttgag
      181 gctgggaaaa agtctttaaa attaaaaaat gtataatatc aggtgttgga aaaactttga
      241 tactatgcgt tttattgtgg gaatatttat ttcattttct cctgaaattg agtttttacc
      301 cagcctaaaa ttcttgactg acttcgttga aatctgtctg ctttggcaag tcatgacacc
      361 ttaaaagtct atttgaatgt tcgttgagac accgctgtct tggacatcct agattcgcaa
      421 aaaagctctc actatcgtga tgattggaaa tatctttcca ttttgaaaac tcttttccac
      481 agtcaaacgt aatagattta aagaggttca ctagaaattg tgccagccac ccttggatgg
      541 attctgccat atcctttgcc ttacgactct tggtcttcaa actgacaatc aattgactat
      601 acctgttcgc tcacaaatag gagagaactt tttacgaaaa tctaatgaat atgccacaag
      661 aacattatac cgcaacgtgt actatttttg gttcatttta ctatagaaac tattgaagca
      721 cctgtacgaa aatatagtag attgaaacta gaatagtaca cctctacttc taaaacattg
      781 ttagaaatcg atttgactgt cccgatcgat tcgtcctgtt attatttcat tttactatac
      841 attatgaaaa aggggagata gaaagcaaac agccttgaaa tcaatgttga ctgcgattat
      901 gaacctgaat cagcccctca aaagggactg tatatgaatg aacgttacca gtgtttaaaa
      961 actaaagaat atcaggcact tttatcttcc aagggtagac aaattttcgc taaacgtaag
     1021 attgatatga aatctgtctt tgggcagata aaggtttgtt tgggttataa gagatgtcat
     1081 ctgagaggta agcgtcaagt gagaattgac atgggattca tactcatggc caacaacctg
     1141 ctgaaatata ataagagaaa gaggcaaaat taaaaagcta gagttccgca attgggaatc
     1201 tctagctttt tgttttctga gaatcatctt gactcagact cttttgacta atgttaccaa
     1261 aaaagataaa gtaactttta accttattta tcgtcgccac tcaacatgtt tttaacacct
     1321 tctacagcac cttctacagc gtctttagcg tcttcggcaa cttcttttac tttagaaaca
     1381 actttttcag ctgctccttc tttttccatt ttttcatcac cgatggcttt cccaacacct
     1441 tctttaatag aacctttagc ttgatttaat ttttcttcta ctgacatgat aatttctcct
     1501 gttatattta ttttatctta gtttacacga gtgttttcgt gagatactac accatttgct
     1561 gcacctttaa cagcttctac accttcgcta actttttctt gaacagttga gaaaccagat
     1621 ccaagaccag atttagcttt ttcgaattgt tctgaagtga attctcctgt tgattcagca
     1681 acgtcagata cgcgatcttg aaggcttact gagtctgctt catgctgttc tttagttttg
     1741 atgtcgacaa cgtttacgtt gatttcaaca atttccaagt cagtcatttt agcaacttct
     1801 gaagatacga tttctctgat ttctgaatat aaagctggaa catttttttg gtactcaaca
     1861 ataacgttta agtcaactgc aacttgtgtt ttaccaactt ctacgttaac accacttgtt
     1921 acgtcatcgc tgttaacgat tttttcttta agatttgaga agaaaccacc atcgattccc
     1981 aaaagacctg aaacgttttc tagtgaaaga ccaatgattt tttggataac tttatcttcg
     2041 taagtaagtt cccctttgat ttcgtgagct acaacagtag catctttctt ttctacgtta
     2101 gtgtttgtgt ttttttcgtt tgacatatga aactccttta attaaattag taatttttat
     2161 ttttttattt atctatatag tttttttcga tatataatcc agctgcaact cccagtgctc
     2221 ctaaaatcaa tacaaatatt gttttgaaga agccaaagga gacaatcaaa caagccagaa
     2281 atacgcctat gagaccagcg ataattggat atcgatattg tttaagccat tccatttttt
     2341 acttccttac ttcacacgac taacagtctt tttgttttga ggttttggtt ggtaattttt
     2401 tactgcaact tcaagtttta cttgacgctc aataccaaaa aactgcttca atccattagt
     2461 tatttcattt tgaattattt ggcatctgtc agcgatgttg tctgaaggaa gaattttacc
     2521 ttctacatga acgaaacatt tattttttcg taaatttaca tgaacagttg ggttcttgat
     2581 caatctatga tcactcacca aacttctaac aaaaccttcg attgccgaat tctttaattt
     2641 taatgtatcg tttttagttt caagttggat ttccaagtaa cgtttaggat aaaacatcac
     2701 aactaaaatg gataataaaa ctaaagttga tagaaccact gtcccccaaa agacatatct
     2761 agcaagatag aattcaacta cggagttctg tctccagcta agtagatgaa tacctagatt
     2821 actaacttga tgataatcta tcaaaacagg aaggaaaatt gtcaagatta aaatacagaa
     2881 aataatgaaa catattttct ttgcttttga catatacaat cctttcgatt taacatttaa
     2941 actatttttc ccgtcattga tttaaaaata gtttgctaac tttactggcg aaaagtttac
     3001 tttctacctg taaagaatga cactacagta atcacaatcg ctgcacctac aatagatggg
     3061 agcaaagcca ttccagcgat tgatggaccc caactaccta aaagagattg tcctgcatat
     3121 gccccgacta aaccagcgaa tacatttgcg atgattccca tagaactact tttttagtga
     3181 ttttacctgc caagagacca ataagacctc cagcaataat tgatcacaac actgcctacc
     3241 ctcctttttt attttaatat caaaaaatca atttctttga ttaatactat tatataactt
     3301 taatatagaa aagtcaatta tttcgattgt tattattata taattttaaa aaatcaaatt
     3361 ctttaattgt tgctattata taatttttaa aattaaaaat ataatcttta gacttgaatt
     3421 tgattctgta ttcacgccct caatagacgg taaaataaga aaattgttta tatattgtct
     3481 ccgtagtgtt attatacgaa ataaaagatt ttaggaaaag tcgttatatc atgctatacc
     3541 tattctttgt ggtataattg caagaggttt aatccgataa tttataaaga gagaaagata
     3601 ttcatgagag atttattatc taaaaaaagt cataggcaat tagaattatt agaattatta
     3661 tttgaacata aacgttggtt tcatcgttct gaactagcag agttattaaa ttgtacagaa
     3721 cgtgcagtca aagatgatct atcccatgtt aaatctgctt ttcctgactt gatttttcat
     3781 tcttctacta atggtatacg cattattaat accgatgata gtgatattga aatggtttac
     3841 catcatttct ttaaacattc aactcatttt tcgattttag aattcatctt ctttaatgaa
     3901 ggttgtcaag ctgagagtat ttgtaaagaa ttttatatca gttcatcttc gctctatcgt
     3961 attattagcc aaatcaataa agtgattaaa aggcaatttc aatttgaagt cagtctgacc
     4021 cctgttcaaa tcattggaaa tgagagagac attcgttact tttttgcaca atatttttca
     4081 gaaaaatatt atttcctaga atggccattt gaaaattttt catcagagcc actatctcaa
     4141 ttgttagaat tggtttataa ggaaacaagc tttccaatga atttgtcaac gcatagaatg
     4201 ctaaagttgc tcctagttac gaacctatat agaataaagt ttggtcattt tatggaagta
     4261 gataaagatt cttttaacga ccaaagtttg gattttttaa tgcaggcaga aggaatagaa
     4321 ggtgttgctc agagttttga atcagaatac aatatctctt tagatgaaga agttgtttgc
     4381 caattatttg tgtcttactt tcaaaaaatg tttttcatag atgaaagtct ctttatgaaa
     4441 tgcgtaaaaa aggatagtta tgttgaaaaa tcttaccatc tattgagtga ttttattgat
     4501 cagatttcag tcaagtatca gattgaaatg gagaataagg ataatctgat ttggcatctg
     4561 cataataccg cacatctgta tcgtcaagag ttgtttactg agtttatttt atttgatcaa
     4621 aaagggaata caatcaggaa ctttcaaaat atttttccaa aatttgtttc agatataaaa
     4681 aaagagcttt ctcactattt agagactctt gaggtttgtt ctagttcaat gatggtaaat
     4741 catctatctt ataccttcat cactcatacc aaacatttgg tgattaattt gctacaaaat
     4801 cagcctaaac taaaggtttt agttatgagt aattttgatc agtatcatgc aaaattcgtt
     4861 gcagagacac tttcttatta ctgtagcaat aattttgaac tggaagtttg gactgaatta
     4921 gaattatcaa aggaatcttt agaagattca ccttatgata tcattatttc taattttatt
     4981 attcctccta ttgaaaataa gagactcatc tattcaaata atataaacac ggtctcactc
     5041 atatacttgt taaatgccat gatgtttatt cgattagatg agtaaccaaa aataacaaaa
     5101 aaacgctatt tcgcgtttga actgtacctc aaaagttaga cagaaaaaat ctaatttttg
     5161 gggtgttttt gttaagaaaa gaccttcaat catttaagca aaatgtacat ctagatttat
     5221 agccctctaa aactcttgct ttttttgtag aagatacgaa aaaagccata aaaccaaggc
     5281 ttttcctgtt ttatgtagat gtttacacat gaaaattgaa gtattttcaa aagctaattg
     5341 gagtgatttt attcatgatg ggataaatga tctggccaaa aatgattgag aaatagttgc
     5401 ttaaaaagca tttgcatgat actatatatt gaaaggaggt gataatatgg tagaacaaag
     5461 aaaatcaatt accatgaaag atgttgcttt agaagcagga gttagtgttg gaactgtttc
     5521 acgtgtaatt aataaagaaa aaggcattaa agaagtaact ttgaaaaaag tggaacaagc
     5581 gattaaaact ttgaattaca ttccagatta ctatgctaga ggaatgaaaa aaaatcgaac
     5641 agaaacgatt gcaatcattg taccaagtat ctggcatccc ttcttttcag aatttgctat
     5701 gcatgtggaa aatgaagtct ataagagaaa taacaaatta ctcttatgtt ctataaatgg
     5761 tacaaataga gagcaagact atctggagat gttgcgtcat aataaagttg atggagtggt
     5821 tgccattacc tatagtccaa ttgaacatta cttgacgtca ggaattccct ttgttagtat
     5881 tgaccgcaca tactcagata ttgccattcc ttgtgtttca tcagataatg atgcaggtgg
     5941 aagagaagca gctaaacaat taattagtaa aggatgtcag catttagcct ttgtgggcgg
     6001 acataataca accattaatg aaaccaaacg tcgtagaatt tcatttgaaa agtatgtcca
     6061 agagcataaa atacctctta gtatttttga tttggatgag acagttactg actattatgg
     6121 aaagctagag agtttcttgg aagaaaattc ttctatagat ggaattttta caatcaacga
     6181 ttttacagct ttggatgtga ttgaaatact agaaaaaaat ggcaaacgta ttcctcatga
     6241 tgtccaaatt attggatacg atggaattaa aatggctgga gatagagatt atctactttc
     6301 aactattgaa caaccattgg aagaaatggc aaaagaagcg gttcgtattt tgtttgatat
     6361 aattgatgga aagactgtta atttgcagac aatcctacca gtaaaatttg ttgaaggaaa
     6421 aacaacaaaa aatgaaaata agtcttgaca gaaagcgcta tcaatgatag aatgaattca
     6481 gataaaaaga tttattttta aaacaaaaat gaaacgtttc aaaaaaagaa ataaaaagac
     6541 agcgccaagc gctatctttt atagaaaaaa tgaaacgttt caaaaaaagg aggttgctat
     6601 gaatagcaaa gcgaagcaag tttctctttg ggaaagaatc aagaaacaaa aactcttgtt
     6661 attgatgact gtccccggtt tagttttaac ctttatcttt aaatacatcc ctatgtatgg
     6721 ggttttaatc gcatttaaag attacaatcc tttaaaagga attttaggga gtgattggat
     6781 tggtttttct gagtttacaa aattcatatc ctctcccaac tttggtatct tgttagccaa
     6841 cacattaaaa ttaagtatct atggtttatt gcttggcttt ttaccaccaa tcattcttgc
     6901 gattatgctc aatcaactct tgagtgaaaa agtcaaaaaa cgaattcagc tcattttata
     6961 cgcaccaaac tttatctcag tcgttgttat tgtcggtatg attttcctct tcttttcagt
     7021 gggaggacca atcaacaatt ttctttctat gtttggaatg aaggctgact tcttgacaaa
     7081 tccagacttc tttagaccct tatacatctt tagtggtatc tggcaaggaa tgggctgggc
     7141 ttcaacgctc tacacggcaa cattggtaaa tgtagatcca gccttagtag aagcagctcg
     7201 actggatgga gccaatatct tccaacgaat ctggcacatt gatattccag ctcttaagcc
     7261 tattatggtt atccaatttg ttttagctgc aggtggaatt atgaatgtcg gatatgaaaa
     7321 agcattcttg atgcagacat cgttaaattt gccaacttct gaaattatct cgacatatgt
     7381 ctataaagtt ggtcttgtat caggagacta ttcttactca acagcggttg gtttgtttaa
     7441 tgcagtgatt aacgtagtat tgcttgttgc agttaaccaa atcgttaaac gcatgaataa
     7501 tggtgaagga atttaaggag gaaagtatga aaaattcgat tatggataca aaatttgata
     7561 gacgtatctt actcttaaat aaaatcatta ttgtctttat cgttttgatg actttgcttc
     7621 ctttacttta tatcgtcgta gcatccttta tggatcctaa ggttctggtt agtagaggga
     7681 ttagctttaa tccagccgat tggactgtag aaggttacca gcgtgtattc agtgaccaat
     7741 ctattctaag aggttttatc aattctctac tatactcttt tggatttgca gctttaacag
     7801 tattgctatc tgtgtttaca gcttatcctc tttctaagaa agacttggtt ggacgtcgtt
     7861 ggattaacta cttcttgatt gtgactatgt tctttggtgg tggtttagtc ccaacttact
     7921 tgctcgtaaa agaattggga atgctcaata ctccatgggc tatcattgtt ccaggtgctg
     7981 tcaatgtttg gaatattatt cttgctaggg cctatttcca aggattgcct gaagaattag
     8041 ttgaagctgc tgtcattgat ggagcgaatg acttgcagat tttctttaaa atcatgcttc
     8101 ctcttgcaaa accaattatg tttgttctct tcctctatgc ttttgtagga cagtggaact
     8161 catactttga tgcaatgatt tatatcaagg atccaaactt ggaaccattg caacttgtac
     8221 ttcgtaaaat tctcattcag agccaaccag gtcaagacat gattggagca caagcggcta
     8281 tgaatgaaat gaaacgttta gctgaattga ttaaatacgc aactattgtc atttccagct
     8341 tgccattgat tgttatgtat ccattcttcc aaaaatactt tgataaagga attatggctg
     8401 gttcacttaa aggataaaaa aagaaaaaat aaaaggagtt ttctcatgaa attcaaaaca
     8461 ttctcaaaat cagcagtttt gttgacagct agtttagcag tacttgcagc ctgtggctca
     8521 aaaaatacag cttcaagtcc agattataag ttggaaggtg taacattccc gcttcaagaa
     8581 aagaaaacat tgaagtttat gacagccagt tcaccgttat ctcctaaaga cccaaatgaa
     8641 aagttaattt tgcaacgttt ggagaaggaa actggcgttc atattgactg gaccaactac
     8701 caatccgact ttgcagaaaa acgtaacttg gatatttcta gtggtgattt accagatgct
     8761 atccacaacg acggagcttc agatgtggac ttgatgaact gggctaaaaa aggtgttatt
     8821 attccagttg aaaatttgat tgataaatac atgccaaatc ttaagaaaat tttggatgag
     8881 aaaccagagt acaaggcctt gatgacagca cctgatgggc acatttactc attcccatgg
     8941 attgaagagc ttggagatgg taaagagtct attcacagcg tcaacgatat ggcttggatt
     9001 aacaaagatt ggcttaagaa acttggtctt gaaatgccaa aaactactga tgatttgatt
     9061 aaagtcctag aagctttcaa aaacggggat ccaaatggaa atggagaggc tgatgaaatt
     9121 ccattttcat ttattagtgg taacggaaac gaagatttta aattcctatt tgctgcattt
     9181 ggtatagggg ataacgatga tcatttagta gtaggaaatg atggcaaagt tgatttcaca
     9241 gcagataacg ataactataa agaaggtgtc aaatttatcc gtcaattgca agaaaaaggc
     9301 ttgattgata aagaagcttt cgaacatgat tggaatagtt acattgctaa aggtcatgat
     9361 cagaaatttg gtgtttactt tacatgggat aagaataatg ttactggaag taacgaaagt
     9421 tatgatgttt taccagtact tgctggacca agtggtcaaa aacacgtagc tcgtacaaac
     9481 ggtatgggat ttgcacgtga caagatggtt attaccagtg taaacaaaaa cctagaattg
     9541 acagctaaat ggattgatgc acaatacgct ccactccaat ctgtgcaaaa taactgggga
     9601 acttacggag atgacaaaca acaaaacatt tttgaattgg atcaagcgtc aaatagtcta
     9661 aaacacttac cactaaacgg aactgcacca gcagaacttc gtcaaaagac tgaagtagga
     9721 ggaccactag ctattctaga ttcatactat ggtaaagtaa caaccatgcc tgatgatgcc
     9781 aaatggcgtt tggatcttat caaagaatat tatgttcctt acatgagcaa tgacaataac
     9841 tatccaagag tctttatgac acaggaagat ttggacaaga ttgcccatat cgaagcagat
     9901 atgaatgact atatctaccg taaacgtgct gaatggattg taaatggcaa tattgatact
     9961 gagtgggatg attacaagaa agaacttgaa aaatacggac tttctgatta cctcgctatt
    10021 aaacaaaaat actacgatca ataccaagca aacaaaaact agaggttgat tatgggagat
    10081 aagaaataca cagtagaaaa agccaatcgt tttatagcag aaaataaaca tctcgttaat
    10141 actcaatata agcctgaaga acatttttca gctgagattg gttggatcaa tgatccaaat
    10201 ggatttgtct attttcgtgg agaataccat ctcttttatc aattctatcc atatgatagt
    10261 gtttgggggc ctatgcactg gggacatgct aaaagtaagg acttggtgac ttgggagcac
    10321 ttgccagtgg cacttgctcc tgaccaagat tatgaccgaa atggttgttt ctcaggctct
    10381 gccattgtca aggatgatcg cctctggctc atgtacactg gacatatcga agaagaaacc
    10441 ggtgtccgcc aagtgcaaaa tatggcattt tcagatgacg ggattcactt tgaaaagatt
    10501 gaacaaaatc cagttgcaac tggatcagac ttgccagatg agttgattgc tgctgatttt
    10561 cgtgatccaa aactctttga aaaagatgga cgctattact ccgtagtagc tgccaaacac
    10621 aagaataatg tgggctgtat cgttctacta gggtccgata acctagtaga atggcagttc
    10681 gaatccatct ttttaaaagg ggtagaacac caaggcttta tgtgggaatg cccagattac
    10741 ttcgagttag atgggaaaga ttgccttatt atgtcaccca tgcgttatca gcgtgaggga
    10801 gactcatatc ataacatcaa ctcatcgctt ttgttcacgg gtaaggtaga ttggggagaa
    10861 aaatgtttta tcccagaatc agttcaagaa attgatcatg gccaagactt ctatgcgcct
    10921 caaacattgt tggacgatca aaatcgtcgt atcctgattg cttggatgca gacatggggg
    10981 cgtacccttc caacccatga ccaagaacac aaatgggcat gtgccatgac tttacctaga
    11041 attttaagat tggaagatgg caaactaaga caattccctg ttaaaaaagg ccaatatcaa
    11101 atccaaatag ataaagattg tcattaccac ttaggaaatg atatagatta tcttgaattt
    11161 ggttatgata gtaatgcgca gcaagtttac attgatcgta gccatcttat tcaaaaaatt
    11221 ctaggtgaag aagaacagga cactagtcga cggtatgtag atattgaagc taaagaattg
    11281 gaagttgttc tagataaaaa ttccatcgag atttttgtca atcaaggtga agcaagcttg
    11341 actgcaactt attacttaac ggtgccagct gagctatcac gaattgatta aaaattaagt
    11401 tatttctcct aaagaaaaag ttctctttct aaaatagtgg aaagaggact ttttgtgttt
    11461 tgggtatata agcttagttt atggtatttg taaaattggt gttggattat gatttaagct
    11521 agttttctaa agaatttgaa aaaaatttta tttaagcaaa aaaaaccctt ggttccaagg
    11581 cttttcctgt tgtatttata tgccccctac agggatcgaa cctgtgaccc acggattaag
    11641 agtccgctgc tctgccagct gagctaagga ggcaaagaaa aaagctgtat tggtgccgaa
    11701 acttcacggt ttgtattgaa cccgcgcaat taagcaggtg ggcaactcgc tctaactgaa
    11761 gctgtttccg tgtgagacgg cctacatgct gttagaagac ttttgtttcc ctaataatac
    11821 aaaaaatagt cggtcaacac ttaagtgtga agtcgtacac cacagcgttt ctatacttat
    11881 atgataccac tttttcaaaa aaaatcaaga ggaaagtgca attttttgaa aaggatttca
    11941 gatttttcgc aaacggtcga tagcttcctt tctttgagcc aaagcccgtt catatttacc
    12001 agtatcttct gcttggaaat agtgatgatt acgaattttt tctggcagat agtcttgctt
    12061 gacccaattt ccaggatagt tgtgtggata gagatagtct tgggcattct ccagttcctt
    12121 gcttccactg tagtgcccat cacgtaggtg tcgcggaata ggcaagtgcc ctgatgtttt
    12181 gaggtcagca agtgccttat ccatagctac ataggctgag ttggattttg gagaaagggc
    12241 caaatcaatc acgacattgg caatgagaat gcgggcttct gggaacccaa tcttctgggc
    12301 agcatccaga gcagtcacgg tatgaatctg ggcctcagga ttggctaagc cgatatcttc
    12361 ataggcgata acagtcaagc gacgagcgag actaggcaga tccccagcct caatcaagcg
    12421 ggcagtatag tggagactgg catccacatc tgagccacga atagactttt gcagggcaga
    12481 tagaacatca tagtgaccgt ctccatcctt gtccatagtg atgtagcttc tctgaagact
    12541 attttccatg atgtctaagg tgatgtggcg aatgccctcg tcattctcag gggtagagag
    12601 aacagctaag tccagtgagt taaaggcaga gcgaaggtct ccgtttgtag aggttgcgat
    12661 gaaatccagc gcatcctcat ctagttctat tggaaaatca aaaccacgtt cagggttact
    12721 tagagctatc tgcagggcct ctttgacgtc ttggttagac agaggttcca actcgaaaat
    12781 ttgaactcgg ctacgaatgg caggagtgac agagaagaaa ggattttcag tcgttgctcc
    12841 aatcatgatg accagtccac tttccaagag aggcaagagg aagtcttgct tggtcttatc
    12901 tagtcgatga atttcgtcta gcaataggac gagaccacca gaaaatttag cttcttccga
    12961 gatttcttgc agtcgctttt tactatcaac tgtcgcattg aaagttcgaa aggcatactt
    13021 ggtcgttcca gcgatggcag aggcaatact ggttttgccg attccaggag ggccatatag
    13081 aatcatggag gacaggcggt tggcttccac catgcggcgg atgatttttc caggtccgac
    13141 cagatgctcc tgaccgatga cctggtcgat ggttttaggg cgcatgcgaa gcgcgagatt
    13201 gtctggcata gcagtccttt ctagcgtgga tttgagtaga atgactcatc tactatatct
    13261 tactatgtcc attctagcct attagttgtg atatttcaat ggttttgtaa taatcaggga
    13321 gtgagataga atctttttta ctatttaatt taatgaggag aggtatcagc atgagagatt
    13381 tgattttcct taaagctcaa aataggatag ttgagcctaa agaagtggaa gtgctgactt
    13441 gagaaataat attgctgaat gtcattgtat gaactataat gaaaagagag gtgataagca
    13501 atggaaatga tggaccaagt caggaaattt tgatttttac aaaacaaatt cgtcattgga
    13561 ttcttagtga tcaagttatt tcagggaaaa gaaaactttt cttccgggaa gatactccaa
    13621 aagagatttt agatttgtac gaaaacatta aatctaaact tgattttgct taccaataag
    13681 tttattctaa taatgggttg aaaaaatatg aaaaatagaa taattgatgt ttttgaagta
    13741 gtaaatcgca tccttgtaat aactgttgaa aatcctgatt tcgaagactt gagagttaat
    13801 catactcaat gaaaatcaaa gagcaaacta ggaaactagc cgcaggctgt acttgagtac
    13861 ggtaaggcga cgttgacgtg gtttgaattt gattttcgaa gagtatcagt ttgtaaaaat
    13921 tggagataaa aaatatagag tacgcagtgt tcctatgatt cattcaactc cgcctcaatc
    13981 tgtcttagat cgagatactt ttacaattga ctatacagat gatgaattgc tcgataaaga
    14041 agcagttttt actactcatt agaaaaatag gtctgaataa attggcttcc cttagaacca
    14101 catctagggg cttttatgta taatagaata ataagtatca ctcctttaca atacgtgtaa
    14161 cacgtgttat aatggtgttg tcaggaggta aaagcgctat gcctatgaca caaaaagaga
    14221 tggttaaact ccttacggcc catggttgga taaagactag aggcggtaaa ggctcccata
    14281 ttaaaatgga gaagcaaggg gaaagactta tcacaatccc tcatggtgag ctgaataagt
    14341 acactgaaag agggataaga aagcaagctg ggttgtaaaa ttcagcccct gttttttgat
    14401 atggaggtag tgaaatgtta gttacgtatc cagctttatt ttattatgac gacacagacg
    14461 gaacagaagc gacttatttt gtccatttcc cagattttga atactcagct acacaaggag
    14521 aggggatttc tgaggctttg gctatggggt cggagtggct agggataact gttgcagatt
    14581 tgatagagag tgatggagag ttacctcagc catcagatat caatagcttg tctttaattg
    14641 ataatgatcc ttttaaagat gatgaagatt tcgtgtcaac ctatgacctt gataaatctt
    14701 ttatttctat ggtatctgtt gatgtatcag aatacctagg aagtcaggaa cccataaaaa
    14761 agactttgac cataccaaaa tgggcagata agttgggacg agaaatggga cttaactttt
    14821 ctcagacttt gacagacgct attgcagata agaaagttca agcctaagat taagcgtggt
    14881 atcgtggtaa tagtcaataa aaaagcacgt ccacttgtgc tagttactcg cctattgatt
    14941 ttatagattt attagccctt tcgagggctt tttatattga tttttatgag aaatgaagaa
    15001 atcagacttt taagaaaatc actgatacca agggtttaaa tgaggtaata tggtataatt
    15061 aggacataaa ataattttgt ggtaagatgg tagtatctat tttagcatat ttccgagcaa
    15121 tcggggcgat taaagagtcg catagaaaga ggacaaaatg gcaacatacg gatttttaga
    15181 tgttttagag gaagagttgg acaagaactt tccctttgac tttgagatta gctgggacaa
    15241 acgcaaccat gcggtagaag tgagttttct attggaagcg caaaatgctg caggtgtgga
    15301 gatggtggat gaagacggag aggtttcatc agatgacatt ctttttgagg aagcggtcct
    15361 tttctacaat cctgccaagt caacagtcaa tgaggaagac tatttgactg ttattcctta
    15421 cctgcctaaa aaaggatttt cccgtgaatt tttagcttat tttgcgcttt tccttaaaga
    15481 tactgctgag gttgggctag atgtcctcat ggactttttg gaagacccag aagcagagga
    15541 atttatcatg gaatggaacc aagaagtctt tgaagaagga aaagttggct tggaagaggg
    15601 agaattttat ccttatccaa ggtattagaa aagattctaa gtggacattt ttaaataatg
    15661 aattcaagga gaagggggag attatgctag aaaaagtcaa acagtttttc aggagcaggt
    15721 cagctaaaac tgagccgtca gttgatattc ttccccgcaa tcgctttgag gatctagatt
    15781 tcgagagagt attgaagtca ggagctcgtc gccttgttaa tgaggaagga cgctatgctg
    15841 aggatgggaa aatcacagaa cttgaatttc ctgaagattt tgcggaattt gaatttctag
    15901 ttggttttaa gacggaggaa gaagagcagt ttcagcaact attagctcgt ttaaatagta
    15961 ttgacaatgc tattcagtcc tatttggaaa gtgagatgca acaacccatc cctcagtatg
    16021 ccaaggatct cggctatact cagaagaggt gggagaaaac cttttacttc catccttgga
    16081 tattaagtgg tgaggaaaac ccgcctaatc ttcgctatgt tgcagattat gtaaatgatg
    16141 agtttacggt ttattttgct aaaaaacatg gcagatggca agcatactgg gatgcagagt
    16201 gccaaaaagt aatcgaagaa agctagctcg tattttccta gagagtaatt gttatcatag
    16261 aaaagagtaa atatcatgga attattgaat agcagaatgg atttccaagg ttgcaagatt
    16321 gccctctttt gtggggataa gctactgacg attttgcgtg atgacaagga cgatatccct
    16381 tgtcccaaca tgtgggagtt gccaggtggg ggaaagagtg tcagggaaaa tctgatatag
    16441 ttttgcatta aaagaatatc ctttcaaggt tattcttttt taattttgtc ccaaaataat
    16501 tgactttgtc ccaaaaatat agtattattt gtataaggag gaatgaatca tgaaaaaatc
    16561 agatgttctt gatttaataa agtatcatta tgagggcaga gagacagaat ttagaaatca
    16621 atccatagca attgctcgga acttcaataa acatggtgat acacaaatag cacaatatat
    16681 tatggggtta atgtctcaaa gtgatagatt catgccacaa atagaaaatc ctagtgagta
    16741 tttgactcct gctaaactag atattggtcc tctcccattg cctctttcaa ttatgaatga
    16801 tttaaaagga ataataaacg ctgtcaatca tcatattgga ataaataaat ttttatttgt
    16861 gggatctcca ggtactggaa aaactgaaag tgtaaagcag gtggctagac ttattggcaa
    16921 ggaattactt gtagtagatt tcagtcactt agtagatagt aagctagggc aaacagtcaa
    16981 aaacttagca actcttttta atgaaatcaa taatcttcct ttcaagcaaa attatatcat
    17041 cctatttgat gaaattgatt ccatagtgtt ggatagggtt aatcagaatg atttaagaga
    17101 aatgggacga gtgacttctg cctttttaaa ggagttggat aggctgtcac cagaaattgt
    17161 attaattgca acaacaaatc tttttgaaaa tcttgataaa gcagttacga gaagattcga
    17221 tgccataatt gactttgacc gttatactga tgaagataaa gtagaagtag ctactattat
    17281 tttaaatgag ttattaaagc aatttaagaa tgtagctaga gatttaaaat tatttaaaaa
    17341 aattatcaat agtgccaatg taataccgaa tcctggtgat ttgagaaact caataagaac
    17401 gtcattggca tttagtgacc catcagatcc gcatgattac caaaaacgcc tgctaagaag
    17461 tttgcataat ggtagaaatt tatctatttc taaattatcg aagctaggtt ttactgttag
    17521 agaaattgag attttgacag gtatttctaa gagtagtgta tcacgagagt taagcgagga
    17581 ttaaaatgaa tacattattg acattacgag gtaaaagttt tacaccaaag tcagcaaagg
    17641 ggaggggacc gataacgatt cccgcagatt ctattgttac gctaaaccat ttaaatgaac
    17701 tttatacatc ccttgaacga gtaaaagaat attggtctaa taacacaatc attgatggag
    17761 tacttattag tgtgtattat aatcgtgtcc tagctaagag caatcgtatc gatggttttt
    17821 ttaatgtggg tggcggaaat gcaattccaa atgaaacgat tgtgggtgca aaatttagta
    17881 atgataagag taggcatatt attacacact acatttcaaa ggaagtgtta gataagacaa
    17941 ttgagcatac taaaaaagtt ataacaatat tcaaagatta ttttgctagt gctcccatga
    18001 cgagtatggt gttctccgac tcttcaaaat ttaatcaaat tgattattct aagtatggtc
    18061 tgtcgaaatc aaaattcaaa caatacttaa gagacgcttg ctttgtcaaa ggatttggta
    18121 ttgaacaggc agatatgtct actatacgta attctattgt aacaatctac gatgtaaaaa
    18181 ctaatctctt aacattactt aaacaacttg atattgatgt ttcagaagct aacatcatgg
    18241 accagacaac tgttttactt gacgaaaaaa atattgagtt actactgcta aaagcacctt
    18301 atctagtatc aatgatagta gaagattttt ctagcctgtc accagagaat ttttataatg
    18361 atgggaacac tttttataat aatctccctt ttccaactaa tgaacctatt attggtgtca
    18421 tcgatacgtt gtttgatgat agagtttatt tcaatgagtg ggtagagtat catgatttaa
    18481 tttcaccaga tattagcaaa ggaagtcaag actataagca cggtacagca gtttcctcgg
    18541 taatagtaga tggagctagt ttgaatccaa aactagatga cggatgtgga agatttagag
    18601 tcagacattt tgggatatct ttacagagtg gtttcaattc cttcacaatt atcaaacaga
    18661 ttagagaaat tgtgtctcaa aatcctgata ttaaggtttg gaacctttcg cttggatcaa
    18721 atgatgaaat tagggaaaac tttatttctg tcgagggttc gttgttagac gagattcaat
    18781 ttgataacga tgtaattttt attattgcag gcactaatgg gattgcccct gatggacaac
    18841 gaaaaaagat tggagcacca gcagattcac tcaattcaat tattgtaaat tctgttgatt
    18901 ttagcaatca agtcgtttct tattcacgcg aaggagttgt cctgtctttc tttatcaaac
    18961 ctgatgtttc atactatggc ggggggaacg gagacttcat aaatgtttgt gaaccactag
    19021 ggctggctcg agtagctggg accagttttg cggctccatt tattgctaga aaaatggctt
    19081 acctcattca tattatggga ttaagtcgtg aagaagcaaa ggctttatta attgattcag
    19141 cgataccatg gaatgataaa aaaacattcg cagacatttc tttacttgga tatggggttg
    19201 tgccaatcaa aatagaagat attttgtcta cacctgatga tgaaattaaa tttatagtct
    19261 cagatgtttc tagagcatat gaaacttata attatgattt cccagttcca atttctaaag
    19321 aacactatcc atatgtagca aaggccacta tgtgctattt tccaaagtgt tctagaaatc
    19381 aaggagttga ctatactaat acggaaatgc aacttagttt gggagtttta gataagaaag
    19441 gcattaaaac aattaataac gacaatcaat attctgaaaa tgcaccagga tatgtgagag
    19501 aaaagtcggc acgaaatatt tttaggaaat gggataatgt caaacattta ggagaaaaat
    19561 tttcttctcg taaaaaagct aagccgattc tgaatccttc taatcctcaa tggggaatga
    19621 gtgtaaaaac aattgaacgg ttaagaaatg atgatggtta tggtatccgt tttggagtag
    19681 ttgttactct aaaggagttg aatggtgtca atagaatcga agattttatt caacaagccg
    19741 aattacgcgg ttggctagtt aatagattgc aagtagaagc tcaagtagac ctctttaata
    19801 gtttaaatga agaaattgaa tttgaatagt ggatatttta tccttattct agatcttagg
    19861 aacacaagag ggcaaagata tgaatattac ttatatagtt ggaaatggtt tggatttgca
    19921 atatggtttg aaaacaagat ataaagattt ctatgaattt caaaatagga cttacataag
    19981 taggaaagag aacgaggaag aatattcaaa tctcatttat gagtctctat tttctgatac
    20041 agtaaatgat tatgaaaatt ggtcagattt tgaattgtca attggtaaat taacaaaaga
    20101 taacgacctc atctcctcaa gtatagaaat aaaggagaaa tttatagatg attttagtga
    20161 aatagttgat gatttaagag aatatctacg catacaacaa gaaaaaaatc ttgagaaagg
    20221 taatgcaatt gactttataa gcactctaga taatatgagg acctctctcc ctgtaattaa
    20281 tcaacctgct atcgataaaa aatataatga aaatctatat caacacgata tcgtgaatat
    20341 attaactctt aattacacaa atgtaatcga taaattatat aatgagtcag caaaatcatt
    20401 tagcaatcaa ttacgaacta ataattataa atttcacatt gcgcctccaa ttcatgcaca
    20461 tggaacggta gatatttgca cagttttagg agttagtgac gagacacaga tttcaaatag
    20521 ttttgatgaa gaacaaaaag aatccttaat aaaaaattta gttttgaaga actatagaga
    20581 aaatatggat gttaaaaata gcgatattat aaaaaattct gacatcataa ttctttatgg
    20641 ggtttctttg ggagagactg atgggtatat ctggaatcag attgctgaac aatcaatcag
    20701 aagttctgtt cctgtcataa tttaccatta tgtacctcat tttgatgcag gaaaccccac
    20761 tagagtaaaa cgcttatata gaaatgtaga agacaaattc atacaaaata gtggaattga
    20821 tttagagtta gagaagaaat taagagataa ccttattgtt gttattggaa agactatttt
    20881 taatctgatg gaaaggtaag caaaatacat aatggaaaca tggcaagagt taaaagttac
    20941 agtgaagcgt gagggagagg agttggtttc caatctcttg attgagctgg gagcgcaagg
    21001 agtcgcaatc gaagacagta tggactatgt gggaaatgtt gaccgctttg gcgagatttt
    21061 cccagaggtg gagcagcaag aagaaatcgt agtgacagcc tactaccctg acacggtgga
    21121 tgtgacagtg gttgaggcgg atttgcaggc ttgtctagca gaattgacag attttatgga
    21181 tttgggagag ttaaaaatag gtacgactgc cttggctgag gaagactggg cagacaactg
    21241 gaagaaatac tatgaacctg ctcgcatcac tcatgatttg accatcgttc cctcttggac
    21301 agactatgag gcgactgcgg gagaaaaaat tatcaagctg gatcctggca tggcttttgg
    21361 tacgggaacc cacccaacta ccaagatgag catttttgcc ttggaacagg ttcttcgtgg
    21421 tggcgaaacg gtgctagatg tgggaactgg ttcaggggtt ctctctattg ccagctcgct
    21481 tctgggggct aaagaaattt tcgcctatga cctggatgat gtggcagttc gtgtggctca
    21541 ggaaaatatt gagctcaacc ctggaatgga aaatatccat gtagtggcag gcgatttgct
    21601 taaaggcgtg gagattgaag cagatgtcat cgtggcaaac atcttggcgg atatcctcat
    21661 tcatctgaca gaggatgctt atcgcttggt taaggatgaa ggttacctga tcatgagtgg
    21721 cattatcaag gataagtggg acatggtgcg cgagttggct gaatcagctg gatttttcct
    21781 cgaaactcac atggttcaag gggaatggaa tgcctgtgtc tttaagaaaa ccaaggatat
    21841 ctctggtgtg attggaggct agcatgcagc agtattttgt aaaaggcagt gctatctctc
    21901 ctgtcactat cgagaacaag gaaaccagta agcatatgtt tcaggttatg cgcttgaaag
    21961 aagaggatga ggttacctta gtctttgatg atggcatcaa gcgcttggcg cgcgtgctgg
    22021 atatggaaaa tcgtcagttt gagttggtcc aagaattaaa tgacaatgtg gaactaccag
    22081 tccaagtgac catcgcatct ggatttccca agggagacaa gctggagttc atcgctcaaa
    22141 aagtaaccga actgggtgct agccaaatct gggcctttcc tgcagactgg tcagttgcca
    22201 agtgggatgg caagaaattg ggtaaaaaag ttgaaaaact agaaaaaatt gcccttggag
    22261 cagccgagca aagcaagcgt aatattgtac caagtattaa acttttcgag aaaaaagcag
    22321 attttctagc tcagctggac cagtttgact ctatcatagt agcctatgaa gaatcagcta
    22381 aagaaggaga agccgctgcg cttctgcaag cagtcactgg tcttgaaaca ggagccaaac
    22441 tgctctttat ctttggtcca gaaggcggtc tctcacctgc agaaatcgaa agttttgaag
    22501 ctaagggagc cgttttggca ggcctaggtc ctcgtatttt gcgagcagaa acagcaccgc
    22561 tttacgcttt atcagccctt agtgttttag tagaattaga gaaataagag gaagaaaatg
    22621 gaacaaaaac accgttcaga atttccagag aaggaactct gggacttaac agccctatac
    22681 caagaccgtg aggatttctt gcgtgcaatc gagaaagctc gcgaagacat caaccagttt
    22741 agccgtgatt acaagggcaa tcttcacact tttgaggatt tcgagaaggc ctttgcggaa
    22801 ttggaacaga tctacattca gatgagccat attggcaact atgcttttat gcctcagacg
    22861 acggactata gcaatgacga atttgccaat attgcccaag ctgggatgga atttgaaaca
    22921 gctgccagcg tagccttgac cttctttgac gatgccttgg tggcagcaga cgaggaagtc
    22981 ttggaccgtt tgggtaaatt gccacattta acagctgcca ttcgtcaggc taaaatcaaa
    23041 aaagcccact acttaggggc agatgtggag aaggccttga caaatctcgg tgaagttttc
    23101 tatagtccgc aggacattta tactaagatg cgagctgggg attttgaaat ggctgacttt
    23161 gaagcccatg gcaagaccta taaaaacagc tttgtcacct atgagaattt ctaccaaaat
    23221 cacgaggatg ctgaggttcg tgagaaatcc ttccgttcct tctcagaggg acttcgtaag
    23281 caccaaaata cggctgcagc agcctatctg gctcaggtca agtctgaaaa actcttggct
    23341 gatatgaagg gatacgactc tgtctttgac tatcttctag ctgaacaaga agtggaccgt
    23401 gtcatgtttg accgccagat tgacctcatc atgaaggact ttgcaccagt cgctcagaga
    23461 tacctcaagc atgttgccaa ggtaaatggt cttgaaaaga tgacctttgc agactggaaa
    23521 ttggacttgg acagcgccct gaatcctgaa gtgactattg acgatgccta tgatttggtc
    23581 atgaagtcgg tagaaccttt ggggcaagaa tattgtcagg aagttgctcg ttaccaagaa
    23641 gagcgctggg tggattttgc tgctaacagt ggcaaggatt ccggtggtta tgcggcggac
    23701 ccatatcgcg tacaccctta tgtactcatg agctggacag gccgtttgag cgatgtctat
    23761 accttgattc atgaaatcgg gcattctggt caattcatct tttcagacaa tcaccaaagc
    23821 tatttcaacg cccacatgtc gacctattat gttgaagcac cgtcaacctt caatgaattg
    23881 ctactcagtg attacttaga gaaccagtct aatgacccac gtcaaaaacg cttcgctctg
    23941 gctcatcgct tgacagacac ctacttccat aatttcatca cccacctctt ggaagccgcc
    24001 ttccagcgta aggtgtatac attgattgaa gaaggggaga cctttggagc aagcaagctc
    24061 aacagcatta tgaaggaagt tttgacagat ttttggggcg atgccattga aatcgacgac
    24121 gatgcagctt tgacttggat gcgccaagct cactactata tgggcttgta tagttacact
    24181 tactctgctg gtcttgtcat ctcgacagct ggttaccttc atcttaaaaa ctcagaaact
    24241 ggagctgaag actggctcaa tctcctcaaa tcaggtggta gcaagacacc acttgagtca
    24301 gccatgatta tcggtgctga tatttcaaca gacaaaccac tccgtgatac catccaattc
    24361 ttgtctgaca cagttgacca gattatcgcc tacagtgctg agttggggga gtaaggggat
    24421 agagaggttg ttatagaatg ggtatggaca gttatttgct taaaagtcca tgtttaaatc
    24481 ccccattcct tttcgaggaa ttctttgccc ttctctgtaa tggtaagtga acgtggcgtt
    24541 tgtgcaggga tgaccaattg tttttcactg aaaaattcta aaagagcatt gccgagagct
    24601 ccgccgacat gatttttacg ttcgctccaa tccaaacatt tagggcaaaa tttccgtttt
    24661 ttctttttca attcatccgt atcaatgtgt aattttcttt ggaaataaga cttcccagct
    24721 tcagtgagtt ggaagtcttt ttctgatcgg attgaagatt actggacttt cagtaaaccc
    24781 agctcgtagc ttggcaccag ctgtcttggt gggcggcgca gcccttcaac aagtttggat
    24841 tttcatcctt gcaccaatcg ctggtggagt tcttgcagcc cttgttgcaa aaaatttcct
    24901 tggaacagaa gaataattga aactcaaaaa gccttgctcc tcatcttgag gaacagggct
    24961 ttttcgtatg atactcttcg aaa
//
LOCUS       DAVHKZ010000031        23995 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000031 DAVHKZ010000000
VERSION     DAVHKZ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23995
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.031"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(209..613)
                     /locus_tag="VVO74_001564"
     CDS             complement(209..613)
                     /locus_tag="VVO74_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU5695565.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGLKYYKK"
     gene            complement(610..774)
                     /locus_tag="VVO74_001565"
     CDS             complement(610..774)
                     /locus_tag="VVO74_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695566.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            complement(1071..1190)
                     /locus_tag="VVO74_001566"
     CDS             complement(1071..1190)
                     /locus_tag="VVO74_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU5695567.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            complement(1193..1351)
                     /locus_tag="VVO74_001567"
     CDS             complement(1193..1351)
                     /locus_tag="VVO74_001567"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695568.1"
                     /translation="MQLGDFAKAGVGGAAARGLQLGIKTGTWQGAATGAAGGAILGGV
                     AYAATCWW"
     gene            complement(1288..1422)
                     /locus_tag="VVO74_001568"
     CDS             complement(1288..1422)
                     /locus_tag="VVO74_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HEU5695569.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWEILPKQVLEEQQQEVFN
                     "
     gene            complement(1491..1760)
                     /gene="blpJ"
                     /locus_tag="VVO74_001569"
     CDS             complement(1491..1760)
                     /gene="blpJ"
                     /locus_tag="VVO74_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEU5695570.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGSGLTCLGGMVGDKLGLSW"
     gene            complement(2226..2423)
                     /gene="blpI"
                     /locus_tag="VVO74_001570"
     CDS             complement(2226..2423)
                     /gene="blpI"
                     /locus_tag="VVO74_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEU5695571.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            2704..4857
                     /gene="blpA"
                     /locus_tag="VVO74_001571"
     CDS             2704..4857
                     /gene="blpA"
                     /locus_tag="VVO74_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HEU5695572.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLVIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            4868..6229
                     /locus_tag="VVO74_001572"
     CDS             4868..6229
                     /locus_tag="VVO74_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU5695573.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSIISSIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTSNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPIITDTREVLITYYVASDYLPLLDKGQTVRLKLEKIGNHGITIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            6286..6441
                     /gene="blpC"
                     /locus_tag="VVO74_001573"
     CDS             6286..6441
                     /gene="blpC"
                     /locus_tag="VVO74_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU5695574.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(6486..7826)
                     /locus_tag="VVO74_001574"
     CDS             complement(6486..7826)
                     /locus_tag="VVO74_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU5695575.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGIGLTFERIFKAFLLKILL
                     AFVFVMIGYMVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQEQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDIERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLRDSSQKLQDNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(7840..8577)
                     /locus_tag="VVO74_001575"
     CDS             complement(7840..8577)
                     /locus_tag="VVO74_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5695576.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(8582..8920)
                     /locus_tag="VVO74_001576"
     CDS             complement(8582..8920)
                     /locus_tag="VVO74_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5695577.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            9196..9525
                     /locus_tag="VVO74_001577"
     CDS             9196..9525
                     /locus_tag="VVO74_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU5695578.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(9693..10742)
                     /locus_tag="VVO74_001578"
     CDS             complement(9693..10742)
                     /locus_tag="VVO74_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5695579.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(10739..11470)
                     /locus_tag="VVO74_001579"
     CDS             complement(10739..11470)
                     /locus_tag="VVO74_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695580.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            11538..11948
                     /locus_tag="VVO74_001580"
     CDS             11538..11948
                     /locus_tag="VVO74_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU5695581.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            11958..12245
                     /locus_tag="VVO74_001581"
     CDS             11958..12245
                     /locus_tag="VVO74_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695582.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            12406..12582
                     /locus_tag="VVO74_001582"
     CDS             12406..12582
                     /locus_tag="VVO74_001582"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695583.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDTTHIYTASRR"
     gene            complement(12611..13747)
                     /gene="dnaJ"
                     /locus_tag="VVO74_001583"
     CDS             complement(12611..13747)
                     /gene="dnaJ"
                     /locus_tag="VVO74_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU5695584.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(13952..14305)
                     /locus_tag="VVO74_001584"
     CDS             complement(13952..14305)
                     /locus_tag="VVO74_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695585.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDYTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(14318..16141)
                     /gene="dnaK"
                     /locus_tag="VVO74_001585"
     CDS             complement(14318..16141)
                     /gene="dnaK"
                     /locus_tag="VVO74_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU5695586.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(16621..17145)
                     /gene="grpE"
                     /locus_tag="VVO74_001586"
     CDS             complement(16621..17145)
                     /gene="grpE"
                     /locus_tag="VVO74_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU5695587.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(17172..18206)
                     /gene="hrcA"
                     /locus_tag="VVO74_001587"
     CDS             complement(17172..18206)
                     /gene="hrcA"
                     /locus_tag="VVO74_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU5695588.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(18370..18879)
                     /locus_tag="VVO74_001588"
     CDS             complement(18370..18879)
                     /locus_tag="VVO74_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEU5695589.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            19486..21819
                     /locus_tag="VVO74_001589"
     CDS             19486..21819
                     /locus_tag="VVO74_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU5695590.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVDKEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            21832..23295
                     /locus_tag="VVO74_001590"
     CDS             21832..23295
                     /locus_tag="VVO74_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU5695591.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTNDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            23295..>23995
                     /locus_tag="VVO74_001591"
     CDS             23295..>23995
                     /locus_tag="VVO74_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU5695592.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLP"
BASE COUNT         7700 a         4843 c         4303 g         7149 t
ORIGIN      
        1 attcatagaa ctatagtaaa atgaaataag aacaggataa atcgatcagg acagtcaaat
       61 cgatttctaa caatgtttta gaaatagagg cgtactattc tagtttcaat ctactatact
      121 ataccatatt ttgtttcgca gggaatctat tataaaaggg taagtattgc aaaaacactt
      181 acccttttct tttatacttc attaagctct actttttata atacttcaag ccccacatga
      241 gcagaagcat gatgattaag cagagaacag cgccaatata agcgattatt tgttggtagg
      301 attctcctgc tgtgatacct ctatacaaac aaataataga cataaaacct gtcaagccga
      361 tgaacataag ttgattggtt ctaggactaa ccaaatcatc atcttcaaac tctcttatcc
      421 tcatttccct agtgagataa acagtaacca aaatagaagc caagttaata actactaaaa
      481 gaaattggaa aactacggaa aaatttaaaa actgacgaga tagaaataga taagtagaaa
      541 caagcaaggg caactgacct aagaacaatc tcgcaaggaa gatgttccgt tttttagcaa
      601 gaaaagtttt catttctttt ctcctttctt tttattgata gcaaaataga tcataactgc
      661 aatcacatag gctatggtat aaaatagctg ataccaagca ctctccctaa gcggatatag
      721 aaagatggac atgattagat acagaacgaa aataatcagt atttttttct tcataagatt
      781 tcctcctaaa tgtgcgattt atcttagttg agcaagaaca tttacactgc tagtatagca
      841 cttattttga ccttggatca ctcaaatcat aaatggtcat caaaacctct tgaattgtaa
      901 aaattaaaaa agcaagcatg aaaaacatac tttcctcttt atattgtatt gataccaact
      961 tgtttgtaga cttttcatcc tgctatcaca tatcattttg acaggcgaaa caaaattaaa
     1021 gaaactcccc tgtaaattaa gctagcaaat acaggggaga aatttatttt ttagggggta
     1081 ctatctgtat cctttttggg aaattttgaa aatatttttc taattaaatt atccatataa
     1141 ggaccaaata taccaactac taaaccaata ataaaacttt taaaatccat aattaccacc
     1201 aacatgttgc tgcataggct acacctccaa gtatagctcc acccgcagca ccagttgctg
     1261 caccttgcca tgttcctgtt ttaatgccta gttgaagacc tcttgctgct gctcctccaa
     1321 cacctgcttt ggcaaaatct cccaattgca tccgccacct tcaacgcaag caagcatttc
     1381 agtatccata acagaaaatt gtgacatcat ttttgtatcc atgacaaata ctcctttttt
     1441 aaaaaactaa aataaatcag aatagaatcc tcataatttt actataagtc ttaccaactt
     1501 agtcccaatt tatcaccaac catacctcct aagcatgtta atccactccc aattgcacca
     1561 atgtgtgctc caacaaatgc accagcaagt ccagctactc ctaaagtggc caaacctgct
     1621 ccagttccac cagttataat tcccgtagtg actcctgtaa tcagtgcatt ttgacaatca
     1681 gtggagctat accccccttc aactttcgca agcatttcag tatccataac ctctaactgt
     1741 gacaacattt ttgtattcat gatgaatacc tcctttttat tttcaatttg ttaccaaagt
     1801 cttaaattca ataaacaaat agatttttta tagtatcttt ttgattttct taaaaaagta
     1861 tatacgtcta ctatcttctt aaaggtagca gtacctattt ttagtctaag atttcaataa
     1921 tcttgagtat ctaaaatatc ttaatttcgt tattctcctt gcaataaaaa gttttactat
     1981 actatttatt aacttgcaga aagcaaaaaa tattagtaaa taatagttta tagttaagtt
     2041 ttttattcct accaatccat caactaagta aagcatcaac gattacataa acgattgata
     2101 atataattaa aattttgcta actatcttat tctcatcatt cttagataac tttgatattt
     2161 tgtaagtaag taaataagac agtaaattaa tagcgataat aatactatat ttaagaatca
     2221 taatcttaca aagaggacat aattcctgaa cctacacaaa taagtgttgc tgctccccca
     2281 gttatcggac cagtcgcagc agctaatagt actgctccaa tacaaccacc gattgcagat
     2341 cctaaattgc ctcttcctcc actaactatt tcgagttctt cattatccat aacagaaaat
     2401 tgttccatca tttttgtatt catgacaaat actccttttt tatttttaat ttttgtcttg
     2461 ttgcaacttt gacaagttta gtatatcatt attttttaat ttttttcatc caaatcttga
     2521 attgccatcg aaacgtcttg aattagcttt tttatttcaa gccacctcta aatgtttaaa
     2581 aaaaataatt tctaatcact tttttaccat tcaggaagtt ttaatgacta ttcaacattt
     2641 cataaaatat gaacttagtt ttatggcata atatacctat ccactatatg aaaggaattg
     2701 ccaatgactt cttataaacg tacatttgtt cctcaaatag atgcgagaga ctgtggtgtc
     2761 gctgccttag cctcgattgc taaattctat ggttcagatt tttctctagc tcacttgaga
     2821 gaacttgcaa agaccaataa agaagggacg actgctcttg gcattgtaaa agccgctgat
     2881 gaaatgggct ttgaaacaag gcctgttcaa gcagataaaa ctctctttga catgagtgat
     2941 gtcccctatc catttatcgt tcacgttaac aaagaaggaa aactccaaca ttactatgtt
     3001 gtctatcaaa caaagaaaga ctatctggtt attggtgatc ctgacccttc tgtaaaaatc
     3061 actaaaatgt caaaagaacg ctttttctct gaatggactg gagtagctat ttttctagct
     3121 cccaaaccca gctatcaacc ccataaagat aaaaagaatg gtctactaag cttccttcct
     3181 ctgattttca aacaaaaatc tctcattgct tacattgttc tctcaagctt attggtcact
     3241 attatcaata taggtggttc ttattatctc caaggaatct tagatgaata catcccaaat
     3301 cagatgaaat caactttagg aatcatctca gttggtctgg ttatcaccta tatcctccaa
     3361 caagtcatga gcttctccag agattatctc ctaaccgttc tgagccagag attaagcatt
     3421 gatgtgattt tatcctatat tcgccatatt tttgaacttc ccatgtcttt ctttgcgaca
     3481 cgtcgtacag gagaaatcat ttcacggttc acagatgcta actctattat agatgccttg
     3541 gcttctacca ttctttctct tttcctggat gtttctattc tgattcttgt agggggcgtc
     3601 ttactggcac aaaaccctaa tctcttcctt ctttctctta tttctattcc tatatacatg
     3661 ttcatcatct tttcttttat gaagcctttc gaaaaaatga accatgatgt catgcaaagt
     3721 aattctatgg ttagctctgc cattatcgaa gatatcaacg ggattgaaac tataaagtcg
     3781 ctcacgagtg aagaaaatcg ctatcaaaat atagacagcg aatttgtaga ttatttggaa
     3841 aaatccttta agctcagtaa atattctatt ttacaaacaa gtttaaagca gggaacaaaa
     3901 ttagttctga atatccttat cctatggttt ggcgctcaat tagtcatgtc gagtaaaatt
     3961 tctatcggtc agctgattac ctttaacaca cttttttctt actttacaac tcctatggaa
     4021 aatattatca acctccaaac caaactccaa tctgcgaagg tcgctaataa ccgtttgaac
     4081 gaagtctatc tagtcgaatc tgaatttcaa gttcaagaaa accctgttca ttcacatttt
     4141 ttgatgggcg atattgaatt tgatgacctt tcttataagt atggttttgg acgagatacc
     4201 ttaacagata ttaatctcac gattaaacaa ggagataagg ttagcctagt tggagttagt
     4261 ggttctggta aaacaacttt agccaaaatg attgtcaatt tctttgaacc ctacaaaggg
     4321 catatttcca tcaatcatca ggatattaaa aacattgata aaaaagtctt gcgccgtcat
     4381 attaattacc taccccaaca agcctatatc tttaatggct ctattttgga aaacttaacc
     4441 ttgggcggta atcatatgat tagtcaagaa gatattctaa aagcttgtga agtagctgaa
     4501 atccgtcaag acattgaaag aatgcctatg ggctatcaaa ctcagctctc tgatggagct
     4561 ggtctatcag gaggacagaa gcaacgaatc gctctcgctc gtgctctttt aactaaatct
     4621 cctgttttaa tactagatga agctactagc ggtcttgatg tcttgactga gaaaaaagtt
     4681 atagataatc ttatgtccct aactgataaa accattctct ttgtagccca tcgtctcagt
     4741 atagccgaac gaaccaaccg tgtcattgtt cttgaccagg ggaaaatcat tgaagttggt
     4801 agccaccaag agttaatgca ggcgcaaggt ttctaccatc atctattcaa taaataagga
     4861 gaatgtcatg aatcctaatc tttttagaag cgtcgagttt tatcagagac gttaccataa
     4921 ctatgcgaca gtgttaatta tacctctttc attactattt actttcatct tgattttctc
     4981 ccttgttgcc acaaaagaaa ttactgtcac ttcccaagga gaaatcgccc ctacaagtat
     5041 catttcatct attcagtcaa ccagtgataa tcctatcctt gctaatcatt tagtggcaaa
     5101 tcaagtagtt gaaaaagggg acttactcat caaatactct gaaacaatgg aagaaagtca
     5161 gaaaactgcc ttagcaactc aattacaaag acttgagaag caaaaagaag gacttggaat
     5221 tttgaaacaa agcttagaaa aagcgactga tcttttttct ggcgaggatg aatttggcta
     5281 ccataatacc tttatgaatt ttactaaaca atcccatgat attgaactgg gtatcacaaa
     5341 gactaacact gaggtttcaa atcaagctaa tcttgccaat agcagttcat cagctattga
     5401 acaagaaatt acaaaagttc aacaacaaat tggagaatat caagagctga gagatgctat
     5461 cataaataac agagcacgct taccaactag caatccacac cagtcaattt tgaatcgtta
     5521 tcttgtagcc tcacaaggac aaacacaagg aacggcagag gagccatttt tatctcaaat
     5581 taatcaaagt attgcaggtc ttgaatcatc tatcgcaagc ctcaaaattc agcaagctgg
     5641 tatcggaagt gtagcaactt atgataatag tttagcaacc aaaattgaag tactccgcac
     5701 tcaattttta caaacagctt ctcagcaaca actaaccgtg gagaaccaat taacagaatt
     5761 aaaagtacaa ctagatcaag cgacacagcg cttagaaaac aataccttaa ccgctccaag
     5821 taaaggtatc gttcatctga acagcgaatt tgaaggtaaa aatagaattc caactggtac
     5881 agaaattgct caaatattcc ctatcatcac agatacaaga gaagtactaa tcacttacta
     5941 cgtagcttct gactatctac ctctactaga taaaggacaa actgtaagat taaaactgga
     6001 gaagattgga aatcacggca ttaccatcat cggccaactt cagacaattg atcaaactcc
     6061 taccagaaca gagcaaggca atctctttaa attaaccgct cttgcaaaac tatctaatga
     6121 ggatagtaaa ctcatccaat atggcttaca aggtcgcgtc actagtgtaa ctgcaaagaa
     6181 aacatatttt gattatttca aagataaaat tttaacccat tctgattaat tttcagataa
     6241 cactctataa ctatttatta tcttatcaaa aaggagaatc ataacatgga taagaaacaa
     6301 aacttaactt catttcaaga actaacaact accgaactca accaaattac aggtggagga
     6361 ctgtgggaag atatcttata cagccttaat ataattaagc ataacaatac gaaaggactt
     6421 catcatccaa tacaactata aaaaataaga ccgagtaaca agaactctcg gtcttatttt
     6481 tttcatcatt ctgtaggtat catagtaagc acctgacgaa agacttgatc ttgacaggta
     6541 gtatttaaac tggcattggg ataactttcc acaatcttca taacggtata gagaccgaca
     6601 cctctctcct cccctttaga actaactcca aaggagaaga tttcagaaat atcgatgccc
     6661 tcttctttga tggagttttc aatgataaaa gtctcctgtg ctccactttt taaaaaggca
     6721 attgaaacat gaggttgacc ggcctctgca ctcgcttcaa tagcattatc acaaaggata
     6781 gacacaatgg ttagaaaatc aagcagtctc atcccctcaa cctgaatctc ttcaggaact
     6841 tcgacattaa agacaatgtc cttttctcta gcttttataa attttccagc taggagactt
     6901 ttgagggcac gatcccgaac attcaccaat ctgcccaggt catatttatt gtcctgcaat
     6961 ttctgactgg aatcccttaa gaccaagtca tagacctctt ttatctgctc catatcctcc
     7021 tcttcaatac ccagacgtaa acttgtcaag aggttggtgt agtcatggcg aaaactcctt
     7081 acttccttgt aaagttcctc tatatgccga ctatagcgtt ctatatctct atagcgcaag
     7141 acctgctctt ggtccagtct atcatggagt ttgtccttca aataggtatc caatttcttg
     7201 ataaccccca taaaaaatag gaggtaaaac actagaatga gatggcgaac agtcgttgat
     7261 tgaatacctt gctcatattc aaagtaagac agactttgta tcaccaaata gtaagccccc
     7321 attatccagt taatcttagt cagggacttt tgaaaacctg tatctagaat ctcccttctc
     7381 aaactagtaa aatcatagtc caaccatttc aaaaaggcta gagaaatgaa gaaattgaaa
     7441 attattatac ataacccagt aaatgagtag ccatcatata cttgctcttg tcccaaaaat
     7501 ggaagcacaa aataggagac tcctctataa aagagattca ccaatatcat tggaaagaga
     7561 ccataaaaga aaaggagttt tttaggaagc cctcttaaca ataagaaaga caagcctatg
     7621 ccgtacaagg gttccataaa ataagatagg taaacatttc ctaccatata gccaatcatt
     7681 acaaaaacaa aggccaacag tatcttcaaa agaaaggcct taaaaatcct ctcaaaagtg
     7741 agaccaattc catctacctt aaagaaaatg acaattttta atccgtgagt aacaagtgta
     7801 tacaacaata tccaagcaac attcataaac tctcctagct cagtgtaagt tattaatagc
     7861 ctcagacact tccctgacct tataacgcgc gatcagacag cttccaccat tgggaaagaa
     7921 aaggagtttt tctttcttat ccaaatgcac cacatttgca ggattgatga gaaaagagcg
     7981 atggcactgc aagagacggg gttcctgctt aaaaacctcc tctaaactcg ccgtaaattc
     8041 tagcctgtcc gtcttggtat agagaataac acgatggggt cttggggatg tttcgagata
     8101 gtaaacctct ttgaaaggat attggaattg ggcaaatttt gatttaaagt aaaagcaatc
     8161 ttccgccaga cttttactat cttgactatt ggcatagagg agggctgtct cgatacgaga
     8221 ttcaaactcc tctgccgaaa gggccttatc aatgtagtcc aaagctgaca cttggtagcg
     8281 aaaggacaga ggcataaact ccgagtgagt cgtcacaaag acgattaggg cataagggtc
     8341 ttgttcccga atctttctag ctacttccag tcccttcatc tcttcatttc gaatctcaat
     8401 atccaaaaag aatagctgat gggccccctt ctcatgcacc tctgccagca gttggtccgg
     8461 cttgccaaat acctcaaaag agctaggaat gatatgatgt gctttcaaaa gtttctcaat
     8521 cgtcgtttca attctagtct gttgggaaaa atcatcttct aaaacaaata ttctcatctt
     8581 cttactctcc ctctttcaac catttttgac gtatttctct atagcgacgt ctggcatact
     8641 tgacagcata ttgaccttct tctccgagaa aaaggattct ttcttgaaaa tcaatcgatt
     8701 ttaatttatc aagattaacc aaacaatttc gatgacatct catcaaagtt tccccacatt
     8761 ggttctcaag attacttaaa ttttgaagca tattaaaact agctttttct gtaacaatct
     8821 gtacggtatg ggctttagtt ggatgtgttt ggatatagta gatatcgtcg atgtttactt
     8881 tatagactgt tttctgtgtc tgaataatca tatgtttcat tggattctcc tcctaagaaa
     8941 agaataacag aaaaggtcta gcccaagcac acccaatcct aaacagtctt tgaaaactcc
     9001 taaaaggatt attttctaca acatcatgat gagcttacaa ctattttatc ataaaattca
     9061 ctcagcgcaa ttcaagacat ttcaatgaca attaaagatt tgaataaaaa aaaagaatta
     9121 aaagtgataa actaacagta tcaaaacaca gttgccagaa gtaagactgg cacccagatt
     9181 aaaggaggca ttcccatgac agatacagac cccatcaaaa gagctcatac tttgattact
     9241 gacttaaaca aagcctacca agcatgcaaa caggcaagcg ctgacgacgt ccgctttcag
     9301 gagcaattaa actctattct tggttttcta gccaaggctg aaacagtgga taatcgattc
     9361 ttgattgaac tagaaaaatt ttaccagact tccagtcttc tcatgggact cagcgctctt
     9421 gatccagatg ctccaactcg cgccgcttgg cgggcctatg accgcttcca ctttgaccaa
     9481 gtcaagacca agttaatact caatgagaat caaagagcaa actaggaagc tagccgcaag
     9541 ctgtacttga gtacggtaag gcgacgctga cgtggtttga agagattttc gaagagtata
     9601 agtctctacg gaccaaccat tatcctgtag taacaaaaaa gaagctgaga cagactgaac
     9661 tcaacttctt ttttagtgtc gtatcagcaa tgttagtcct gcatctgacg ttttacctga
     9721 taaggcaaat acaagactag taaaaccaaa ccagctccta gtaaggctag aagggccagt
     9781 ttttcttgga aggtaatcaa cccaacaact aattccacaa gtaaaacaaa actggtcaat
     9841 cctcgaacta cctcctgcaa gcctttttcc ttttgcccct tgtccagcgg aaagagttgg
     9901 gtcaaatact ggtagtcaaa ggcatgatag agggccagca actggaagag caagaggtag
     9961 ttaaagagaa ctaccactgc tgtcgcaatc caagcttgct cgataaaaac ctgcgccagt
    10021 acggaaagta atagaagacg aagactgaga gcaaagaggt cgccatttcg cagataagaa
    10081 cgcagataga gattttgcca aatcttccca ggcaccttct gaacagcctt taagataaag
    10141 tccagatagg cacgacgctt aacgctgttt gaaattccct tgacctgcgt aaagagggca
    10201 aagaaacgaa gcaagacttg cttacgcttg ctttcttgag aaataacata gtcccagtcc
    10261 agtccagttt cagtgaaaaa tttgctggcc ttttgacgaa agtggaaata ttttcctacc
    10321 cccaataaaa gcacatagag cagaaaaact ggcaagccat aacccattgc taaaaataaa
    10381 ggcgcaaata acagcaagaa aagggtctgt acaaagagcc aaaagactag ggaaatgcca
    10441 gtttgacgct tgagatggag cttgatttcc tcttctccaa ctaagagaaa gagcttgtct
    10501 ggagcctcca tataggtggc aattcctccc caaagtaaaa gtaaaacaga cgtaattcct
    10561 acaaacaaaa ggataggcca atgattttca ggaaaatgtt gtaagagttg actgtactgg
    10621 taggctagaa agcccaacag gacaagcagg aacaagacaa agtggtcatt gagcacatag
    10681 cgcagataac caagacactc cttacgaaag gcctgctttc tctttaaaaa caagtctttc
    10741 ataggtcctc ctcttttgtc agagccaagt aaatatcatt caaactagcc tcaggcatat
    10801 caaaggcttc gcgtagttgc aggagattgc ctttggcacg cacctctccc ttgtgaagaa
    10861 tgacaaaggc atcacacatc ttctccgccg aatccagcac gtgggtactc atgagaatag
    10921 acttgccctt ttgcttctcc acttccaaaa gctgaatcaa atcagaaata gccagcggat
    10981 caagaccaag gaaaggctca tccacgatga aaagacttgg atccaccaca aaagcacaga
    11041 taatcatgac cttctgcttc atcccttttg aaaaatgaac agggaaccag tctaatttct
    11101 gttccaaacg gaacattttt aacaagggct ctactcgttc gaaagccact ttttgctcaa
    11161 taccgtaagc catagcaacc gtttcgatat gctctctgag ggtcaattcc tcatacagac
    11221 taggcgtctc aggaatgtag ccaatctgct tgcggtagct agtcgcatct ccttgcagag
    11281 tcaggccatt gatattgatg gagccactat aaggtgccaa cagaccgata atctcattga
    11341 tcgtcgttga tttcccagca ccattgagac caatcaaacc gaccaactgc ccactttcaa
    11401 cagtaaagga cacatctttc aaaacaggaa catgaacata gccacctgtc aggtttttaa
    11461 tttctaacat attttctcca aatctggtat aatgtagcta tattatatca aaattcagta
    11521 cagtagaggt agattttatg tcagattgca ttttttgtaa aatcatcgca ggggaaattc
    11581 ctgcttcaaa agtatatgaa gatgagcagg tccttgcctt tcttgatatc tctcaagtaa
    11641 cactaggaca caccttggtc gtgccaaaag aacactatcg caatcttttg gagatgaatg
    11701 ctacgagcgc cagccaactc tttgcccaag taccaaaagt agctcaaaaa gtcatgaaag
    11761 tcactaaggc tgctggtatg aatatcattt ccaactgtga agaagtcgct ggtcaaacag
    11821 tttttcatac tcacgttcac cttgtgcctc gctacagtgc tgacgatgac ctcaagattg
    11881 attttatcgc ccacgaacca gactttgaca aacttgctca agtcgctgaa accatcaaaa
    11941 acgcttaagg agttgctatg aaattatcca acctactgct atttgcagga gctgcagccg
    12001 gaagttatct ggttacaaaa aatcgccaaa ccatcacaga tgaagtctta aataccactg
    12061 accgcgttca agctatcaaa gacgatgtgg atattatcca aaatagcctg caaatcatcg
    12121 accagcaaaa agaacttatc aaggaatacc aagaagactt gacttacaag tttaaggtct
    12181 tggaaaagga tatccagact agactagctg tgataaaaga aatgcaggga actgaagata
    12241 agtaaaaaga gcccccggct cttttttaaa acgtaaacaa gttatagtga attgaattta
    12301 gaatagcaca tcatagtttc taaagcattg ttagagatta ctttaaaatc ctcttatcaa
    12361 tttgttcata ttctatttca atctactata tatatcccat caactatgca tcataattta
    12421 ggtaactcat actcaataaa aatcaaaaag caaactagaa agctaggcac agactgctca
    12481 aaacaccgtt ttaaggttgt ggatagaact gacgaagtca gctcaaaaca ctgttttgag
    12541 gttgtagata cgactcacat atatacggca agccgacgct gacgtggttt gaagagattt
    12601 tcgaagagta ttattctcca tcaaaggcat ctttaatatg gtcaaagaag ccttttttct
    12661 ttggatttac tttcaagtca ccagcagccg cgaattcttt caaggctact ttttggcggt
    12721 cgttcaagcc tgtcggtgtt acgacattaa cagtaacgta ttggtcacca actgcaccgc
    12781 cacgaaggct cggtgccccc ttactacgta ggcggaattt cttaccagtc tgagttccct
    12841 ctggaataac caattcaaca tcaccgtgaa cagttggaat atctactgta tcaccaagag
    12901 ccgcttggac aaagttgagg ttgagattgt agaagatagt cgttccttca cgttcaaact
    12961 tgtcgctagc ttctacagaa actactacat acaagtcacc ataaggtcca ccgttaaagc
    13021 ctgcttcacc ttgaccagcg aggcgaattt gttgacctgt ttccacacca gcagggattt
    13081 tcacatgtac gctatgagct tgtttctcat gacctgttcc atgacaggtt gtacatggat
    13141 atttgatttc ttttcctcga ccgtgacaga catcacaggt tacttggcga cgcatcatac
    13201 caagaggagt ctgcgtatcg acgttaatga caccagcgcc atgacagcgt ccacaagtga
    13261 ctggacttgt ccctggctta gcaccagagc cattacatgt acgacagcca gcttcacgat
    13321 gatacttaac ttccttctca gttccgaaga tagcttcttc aaaggtcaaa ttgacacgat
    13381 actggagatc atctccttgg cgaggagcgt ttggattgcg cgaagaaccg cctccgccga
    13441 agaaacttga gaaaatatcc tcaaaaccac cgaagccacc tgccccattg aaaccgccga
    13501 aaccaccagc tccaccaaaa ccaccattgg cgcctgcagc accatactgg tcataggcag
    13561 cacgtttttg gtcgtcactc aaagtctcat aggcttcttg aacttccttg tacttgtcct
    13621 cagcaccagg ctccttgttg atatctgggt gatatttttt ggaaagctta cgataagcct
    13681 ttttgatctc gtctgccgaa gcgttttttg acacccccag acgatcataa aattcagtat
    13741 tgttcataca agataccaag accgtaaaat tcgactgaaa aataggaaat ctgacgctgg
    13801 agcgacgctc ctagacagat ttctcttttt tccgagaatt taggtcgggt tcaattcctt
    13861 tcttttatat tgatgagata atactccagc cactcggccc tatccctttt taccgaaaaa
    13921 cagaggctgg gttgcaacct ctgtggttag attattcatt tgaaataaaa atggttgtat
    13981 tatctctagt agtaatcttc aaagaccttt tagctaaatc aaactcaaat ttattatagt
    14041 gtgggtcttg tgttttatat aggtgtaact cctgacatat atgatccgaa aagtaaatca
    14101 taacatcttt aaacacagaa gtgtagtcat atttactctt accaacagct acttctgtaa
    14161 attctttata aatgacattt ccatttcttt ccacagtcac cagcatttct gttggattat
    14221 aatccaaatt aaataattct tcaaaaaact ttatcttttc atgataatct gcaatgtcag
    14281 aaagattatt tttattaaca ctcataacac tagcccctta cttttccgta aactctccgt
    14341 ctacgacgtc atcgcctgcg tttcctgttg cttgtgcgcc ttctgctcct tcttgagctt
    14401 gttgcgctgc tgcggcttgt tcgtagagtt taacagcaag tccttgagct ttttcgttca
    14461 atgcttcaag ttttgctttc atgtcgtcca agttgttgtc ttcttgagct ttcttaaggt
    14521 catcaagggc agcttgggca gcgtcacgtt ctgcgtcgaa gcctttacct tcagtttcct
    14581 tgattgtctt ttcagtcgca aagattgctt ggtctacttc attacgaagg tctacttctt
    14641 ctttacgttt cttatcggct tcagcgtttg cttctgcatc tttcatcatg cggtcgattt
    14701 cttcgtcagt caaacctgag ttcgattgga tgacaatagt ttgttctttt tgagttccaa
    14761 ggtctttggc cttaacagac acgataccgt tcttgtcgat atcaaatgtt acttcgattt
    14821 gaggaattcc acgaggtgca gctgggatat cagtcaattg gaagcgtcca agagtcttgt
    14881 tatctgctgc cattgggcgt tcaccttgaa gaacgtggat atcaacggct ggttggttgt
    14941 ctgctgctgt tgagaagact tgtgatttag atgttgggat tgtagtgttg cgatcgataa
    15001 gttttgtaaa tactccaccc attgtttcga taccaagtga caatggcgtt acatcaagaa
    15061 ggacaacatc cttgacatca ccagtaatca caccaccttg gatagccgca cccatagcaa
    15121 ctacttcatc agggtttact gatttgtttg gttctttacc agtttcagct ttaacagctt
    15181 caacaacggc agggatacga gttgaaccac caacaaggat aacttcgtcg atttctgaca
    15241 agctcaaacc tgcatctgaa agggcttgac gaactggaac ttttgtacgt tcaacaaggt
    15301 cacgagtcaa atcatcaaat ttcgcacgag ttaaagtcat ttccaagtga agaggtccag
    15361 cctcacctgc agtgataaat ggcaagctga tttgtgttga agttacacca gaaaggtctt
    15421 tcttcgcttt ttcagccgca tctttcaaac gttgcattgc catcttgtca gtagacaagt
    15481 cgataccgtt ttctttcttg aattctgcta ccaagtggtc aatgattttt tggtcaaagt
    15541 cgtcaccacc aagtttgttg tcccctgcag ttgacaatac gtcgaagaca ccgtcaccca
    15601 attcaaggat agagacgtcg aatgtaccac caccaaggtc aaataccaag attttttctt
    15661 ctttgtcagt cttgtccaaa ccataagcaa gagctgctgc agttggttcg ttaacaatac
    15721 gttctacttc aagaccagca attttaccag cgtcttttgt tgcttgacgt tgagcgtcgt
    15781 tgaagtaagc cggaactgtg ataacagctt tggttacttt ctcaccaagg tagtcttcag
    15841 cgtagccttt caagtattga aggatcatag ctgagatttc ttgtggagtg tattcttttc
    15901 catttgcaga aactttttca gaagttccca tcttagattt gatagagata actgtatctg
    15961 ggtttgtgac tgcttgacgt tttgcagcat caccaacgat gatttctccg tttttgaatg
    16021 agactacaga tggagttgtg cggtttcctt ctgggtttgc gatgattttg ctttcagttc
    16081 cttcaagaac tgcaactgct gagtttgttg tacctaagtc aataccgata attttagaca
    16141 tgtgtttttc tccttgttag ttaattttct atttttcttt ttgatactct tcttaagtgg
    16201 cgacgccgtc agagcttgac ttcgtcaatc tctttgacta aactttgagc ctaaggtctc
    16261 aaaatttgcg caaatagcgc cacggcgaag agtatcgtgt ttggttcgct tcgctcacta
    16321 ttacaaagcc aaacatattt tatctttctt catagtttat tgtcgtttcg gacaagtttt
    16381 ctattatgta aattgcgaca cgaagagtcg aaatcgattt tatttcgacg acgagttagt
    16441 aaggaagcta ggcaaacgcc atagcgattg ccgttttctg acgagttgct ttagctaccg
    16501 tcagaattgc cgaatcgaac acgccctaag ctctgagtaa aaaagataga ttttcttgtg
    16561 ttcatcgaac acttcgtcaa tctcctattt ttactgcgag ctttttacgg gctttgtatc
    16621 ttagttatac accactacca ttgctgggcg taggatgcgg tcatggagtt tgtagccttt
    16681 ttgaaagact tgagcgatgg tatctactgg gtgttcatcg tctgctggga gagtttggat
    16741 ggccatatgg tagttatggt caaattcgcc atctgctgcg atttcttcaa ttccttcttc
    16801 tttcaaagcg tgaatcaagc tttcttgcac catccccaag cccttcttca catcatctgt
    16861 caaaccttca actgcaagtg cacgctcaag gttgtcaaga gatggtaaga ttgcttttgc
    16921 caagtcctgg ctacgataac gttgcaagtt ttgacgttct tcattggcac ggcgttggat
    16981 attttgcatt tctgcatgag cgcgaagata tttgttttcg aactcatctg cacgttcatt
    17041 tgccaagtcc aactcagact tttcaggagt tgtttcttca gctgtttcca caacttcctc
    17101 ttcttgaact tcttctactt cttcattttt tatatcttgg gccatgttcg cctcctttaa
    17161 tgatttcaat cttaatgtac ttcgtaatga ttactgctga ggtagcggta aaaatctgtc
    17221 aacttcatgg tcaaaacacg gttgaccaca ttgatttgat tgattagctg ttggtaatcc
    17281 agattaactg gaccgataat ggctagaatt ccaactcccc gataaggaat gaggaactta
    17341 ctactaatca ccgctaggtc agctaaacag gactcttgac cgtctgcaat acgaacattt
    17401 tgcatctgat cctcacgcaa cccctcacga atctccaagg ccaccttttg cggttggtca
    17461 aagaactgat aggctgctag attggcaaaa ttcaagagat tgaccttgcc cgccatcaca
    17521 atgttttcgt tgaacatttc cttaaagatg tgttcaaaga gatcgatgac attatccgtt
    17581 gttgtaaagt aacgctggat aatctgcgga atctccgtcc gaatcttgta gtgaatatct
    17641 aaaacggtgt gaccgaggaa acgttcctga atgatgctct tcagtttcag caaatcctcc
    17701 tgcaagaagt tccttggaat cagaaactga ctagtaaccg ttcgcgactc gtctagggta
    17761 aataccgcca aggctgtatg ttgccccaaa acaacgatat caaaggctgt caaacgttgc
    17821 ctgctcggct caacatccag tgccactacc gtacagccac tcaggtctgt tagcaagtta
    17881 gcagcctctt gcagaatatc ctccaatttg aagaattcct gatcaaaggc tttgacaatc
    17941 tcatatacct cattttcagc cagccggtga aaatccagtg agtgtttcac atagtactga
    18001 aaaccagcaa cacttggcat ccgaccgctt gaagtatgag ccttctcaag caacccttgt
    18061 ttttctagtt ccgccatgtc attacgaatg gttgcactgc tagagttaat agactcttgc
    18121 aaggcttttg atccgacagg ttcgtgcgtt ttggtaaaga tgtcaataat cagatttaaa
    18181 atatcctgct gacgctctgt aaccatctca tcactcctct ctgtctgatc aattagcact
    18241 caatgcatcc aagtgctaac ttatgattct attatacacc cttagaagag aatgtcaaga
    18301 caaaaactca aaaaattagc actcttttat caagagtgct aaaaatcaat ctgaagacct
    18361 agaaccttgc tattcatcta ctcggtattt cctttttagt ctgaaataac catgaattag
    18421 ataagaaatc agaaaagcat ataaaacaaa aataagaaag aaagacatag aaagatcctc
    18481 tctaaacaaa ctcgtacaaa caacaagacc acctaagaaa gtagttgtac aggaacgaag
    18541 tctagatcgc ataacttccc atttgagccc cttactcata tagacttgat cctctggaag
    18601 taaatcagaa gacgatttac gaagaatcga acaagaacct gctcctatca attcccaacc
    18661 tctatctcta aaatcttgca gttcatgctt atatttttta agaaatctag aatcatagat
    18721 acggtagatg acatcgtctg gttgacattg gtcaaaatag aacaaaccaa aacgactcgt
    18781 tctatacctc caacctttca aatgcatctc atgtaaatat tcttcttcct tgtccaaatc
    18841 aacaatagtg aaaatccgaa attctactct gctattcatt gtcttacccc aaaattagaa
    18901 aacatgcctg gcgttattta ttagataatt ctttccgctt ttgactcaat ctccaaaaaa
    18961 tataagaaat ctgaatcgca aaaactatca ataaaaccca atctattatg aaagtcaaaa
    19021 acacttccca actgaaagaa ctacctccag tgacaaactt tgagaaaaac ggtagtagag
    19081 ctaaaaagag aagcaaaata ggaagcatcc gcattgttaa aatccttttg gcataaaaaa
    19141 atctttattt aaacgaaaat attatggcaa aatttacgcc agtttttgaa cggctgatgt
    19201 agatatttta tactttcaaa atgtttaaat gtgattattt atttttgaaa aatagctcac
    19261 cagcccgact gaaagtgctt ataaatgata ataagtcgcc tgccgaaaac agcgaaaaat
    19321 agcggtgtta tgcggagata atctgacgcg atgcgaaagt atattgcata cttattttca
    19381 acaatttagc agagtatttt tataagtgtg atataataga agtataattt gttctgatag
    19441 tttattttat ggagaagtag atttttagaa tgcggagggt tcaatatggt tgagtttata
    19501 aagtctaaga aagaaatgag tgaggaggat attaaagcaa atttcatcac tcctgctatt
    19561 gtatccaaag gatggaaaaa tggtgagcat atcgcttacg aagaatactt cactgatggt
    19621 cgaattgagg ttagaggaga taaggctcgt cgtaaagaag gaaaaaaatc agactattca
    19681 ctgtattacc aatttggaac tcgaattgca attgttgagg caaaggataa taaacacagc
    19741 gttcgagcag gattacaaca agctattgaa tatggagaga ttttagatgt tccatttgtt
    19801 tattcttcga atggtgatgg ctttattgaa cacgaccgta tcacgagaga agaacgtgag
    19861 ctggagttag acgaattccc tactcgtgaa gaattatttt ctcgtatgac gaaggaaaaa
    19921 ggattgacgt acgaaattac agaagctatc tcaactccat actatacaga cgccttctca
    19981 atgaaaacgc cacgctatta tcagcaaata gctatcaacc gtactattga aacagttgcc
    20041 agaggacaaa aacgagtaat gtttgtgatg gcaacaggaa cggggaaaac gttcatggct
    20101 tttcaaatta ttcatcgcct tcgaaaagct ggtttggcta aacgagtttt attcttagcg
    20161 gatagaaaca tcttagtaga ccaaacgatg gctgaagact ttaggccatt cgaaaaggta
    20221 atgacgaaaa ttacaccaaa acttttgact gctcctgaaa aattaaattc ttttgaaatt
    20281 tatctagggc tttatcagca actaactggt gaagatggaa ctgaaacaca ttatcaaaaa
    20341 tttgacaaag acttctttga tttaatcgta attgatgaag cgcaccgtgg ttcagctaag
    20401 gaaaacagta actggcgtaa gataattgat tatttcagtt ctgcgacaca gattgggatg
    20461 accgctactc ctaaagaaac caagaatgct tccaatacgg aatactttgg tgagccaatc
    20521 tatacttata gtttaaaaca gggaatcgag gatggttttt tggctccata tcgtgttatg
    20581 agggttaatt tagatgtgga tgtggatggt tatcgtccag aaactggaaa agttgatgct
    20641 aacggacaat taatagaaga taggtactac ggcaggaaag attttgataa aaccattgtc
    20701 attgatgata gaacgcaaag agttgccaag tttgtttctg attatatgaa gcaaaacaat
    20761 gcacgatttg ataaaacaat tgttttttgt gttgatattg accatgccga gcgaatgcgt
    20821 gctgcacttg taaaagagaa tctagactta gtccaagaag actatcgtta tgtcatgcaa
    20881 gtaactggtg acaacgctga aggaaaagct caactggata actttatgga tgtcaattct
    20941 aattttcccg ctatggtaac aacgtctaaa ttattaacga caggagttaa tgctaaaaca
    21001 tgtcgtttga ttgttttaga ctctaatatc caatccatga ctgaatttaa acaaattatt
    21061 ggtcgtggca cacgtcttta tcctcaaaag gggaaagaat tttttacgat tattgatttt
    21121 cgaaatgtta ccaatttgtt tgctgaccct gattttgatg gtgatcctgt gaaggtgctg
    21181 gaaacaggtg cgaaaacagt cagtggttct acgcccggtt tcgtagataa ggaaggtgac
    21241 ccagtagaaa aatatatcgt tacagacaag caggttacca ttcttaattc tactgttcaa
    21301 gtattggatg aaaacgggaa actgattacc gaaagcctga ccgactacac tcggaagaat
    21361 atcttaggta gctacgccac tttgaacgat tttatcacag tttggcatac ggcggataaa
    21421 aagaagctta tcttagacga actttataaa aaaggagttt atctagatgc tattcgagag
    21481 tcggagggaa tatcagaaca agaaatcgat gattttgatt tactcctaaa acttgcctat
    21541 ggtcaaaaag aattaaccaa aacggaacgt atcaataaac tcaaacaaag cggatattta
    21601 tataaatata gtgaggaagc gcgtgctgtt ttggaaattt tactgaacaa atacatggat
    21661 aaaggtattg gagaactcga aagcattgaa acattaaaac ttccagaatt tcagatatat
    21721 ggtggaacct tcaaaatcat caatacttat tttggagata aaaaacgata tttacaagca
    21781 attaaagaat tggagcaaga gctatttaca gtagcttaat gaaaggaaag tatgtcaatt
    21841 acatcatttg taaaaagaat tcaagatatc actcgaaacg atgctggtgt taatggtgat
    21901 gctcaacgta ttgagcaaat gtcttggtta ttattcttaa aaatttatga tagccgtgaa
    21961 atggtttggg aattagaaga agacgagtat gagtcaatta tcccagagga attaaaatgg
    22021 cgaaattggg ctcatgctca aaatggggaa cgggtattga caggcgatga attacttgat
    22081 tttgtcaata acaagttatt caaagagttg aaagagcttg aaataacttc aaatatgcct
    22141 attcgaaaaa cgattgttaa atcagctttt gaagatgcga acaactatat gaaaaatggc
    22201 gtcttgttac gccaagtcat caatgttatt gatgaagttg atttcaatag ccctgaagat
    22261 cgtcattcgt ttaatgatat ttacgaaaaa attcttaaag atattcaaaa tgctgggaac
    22321 tcaggagaat tttatacgcc acgtgcagcg actgatttta ttgccgaagt tcttgaccca
    22381 aaacttggag aatcaatggc agaccttgct tgcggaacag gaggcttctt gacttcgact
    22441 ctgaaccgtt taagtagtca acgtaaaact agtgaagata ccaaaaaata taatacagct
    22501 gtttttggta ttgaaaagaa agcatttcct catcttttag cagttacaaa tctgtttctt
    22561 cacgaaattg atgaccctaa aattgttcat ggaaatactt tggagaaaaa tgttcgtgaa
    22621 tatacgaatg atgaaaaatt tgacattatt atgatgaatc caccttttgg agggtcagaa
    22681 ttagaaacaa taaaaaataa ctttccagca gaattacgga gttctgaaac agctgattta
    22741 tttatggctg tcattatgta tcgtttgaaa gaaaatggtc gtgttggagt tattttacct
    22801 gatggttttc tatttggtga aggtgtaaaa actcgcttga aacaaaaact ggtagatgag
    22861 ttcaacttgc atacgattat taggttgcct catagtgtct ttgcaccgta tacaggaatc
    22921 catacgaaca ttcttttctt tgataaaaca aagaaaacag aagaaacttg gttttatcgt
    22981 ttagatatgc cagatggtta taaaaatttc tcgaaaacta agccgatgaa gtcagaacac
    23041 ttcaatcctg ttcgtgactg gtgggaaaat cgtgaagaga ttctggaagg taagttctac
    23101 aaatctaaat catttacacc tagtgaattg gctgagttga attataattt agaccagtgt
    23161 ggttttccaa aagaggaaga ggaaatctta aatccctttg agttgattca gaattatcaa
    23221 gcggaaagag caactttaaa tcataagatt gataatgtat tagctgatat tttgcagttg
    23281 ttggaggaca aataatgaca ccagaacaac ttaaagcaag tattctccaa agagcgatgg
    23341 aagggaaatt agtgccgcaa aatcccaatg acgaacctgc aagtgaatta ttaaagagaa
    23401 ttaaagctga aaaagaaaaa cttatcagtg aaggaaaaat caaacgagat aaaaaggaaa
    23461 ctgagatatt tcgtggtgat gatgggaaac attatgggaa gtttgctgat ggaagtactc
    23521 aagaaattga tgttccttat gatattcctg atacttggga gtgggtgagg ttttctacat
    23581 tggttgaaat tgtcagaggt ggctctccac gaccaatcaa agattatctt acttctgaag
    23641 tagatggaat aaattggata aaaataggtg atactgaaaa gggtgaaaag tatataaata
    23701 atgttaaaga aaaaatcaaa aaatcagggc ttaacaaaac tagatttgta aaaaaaggta
    23761 catttttgtt aactaattct atgagttttg gtagacctta tattttgaat gttgatggtg
    23821 caatacacga tggatggttg gctatttcga actatgaaaa ctcattaaat aaagattatc
    23881 tattctatat tctttcatca aatgtagttt attctcaatt tctatctcta attagtggag
    23941 ctgttgtgaa aaacttgaat agtgataaag ttgcttctat tcttatccct ctccc
//
LOCUS       DAVHKZ010000032        23843 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000032 DAVHKZ010000000
VERSION     DAVHKZ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23843
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.032"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(381..1577)
                     /gene="tuf"
                     /locus_tag="VVO74_001592"
     CDS             complement(381..1577)
                     /gene="tuf"
                     /locus_tag="VVO74_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU5695593.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2499..3368)
                     /locus_tag="VVO74_001593"
     CDS             complement(2499..3368)
                     /locus_tag="VVO74_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU5695594.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3592..4212)
                     /locus_tag="VVO74_001594"
     CDS             complement(3592..4212)
                     /locus_tag="VVO74_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU5695595.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKAPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPIPQPNPEHPSVPTPNPELPNQETPIPEPTPEPGTPKTETPVNLDPEV
                     PTYETGKREGLSNTGTEANATLASAGIMTLLASLVLGFFKKKEDEK"
     gene            complement(4170..5276)
                     /locus_tag="VVO74_001595"
     CDS             complement(4170..5276)
                     /locus_tag="VVO74_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEU5695596.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEVDTNSASLTGNIVSEGRTVTLVYRESEAPTTVTVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKENRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5387..5641)
                     /locus_tag="VVO74_001596"
     CDS             complement(5387..5641)
                     /locus_tag="VVO74_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695597.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5981..6427)
                     /locus_tag="VVO74_001597"
     CDS             complement(5981..6427)
                     /locus_tag="VVO74_001597"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5695598.1"
                     /translation="MDETGIDRYLYRPYAGAPRGEKVYEKISGRRFERISIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNAGFHPKNILDELCIQDKHF
                     FLPLPPYSPDLNPIEQAWAILKKKVTDLLREVPTIFECLECFFKTR"
     gene            complement(6500..6825)
                     /locus_tag="VVO74_001598"
                     /pseudo
     CDS             complement(6500..6825)
                     /locus_tag="VVO74_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7059..8777
                     /locus_tag="VVO74_001599"
     CDS             7059..8777
                     /locus_tag="VVO74_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU5695599.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8888..9235
                     /locus_tag="VVO74_001600"
     CDS             8888..9235
                     /locus_tag="VVO74_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU5695600.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9514..10350)
                     /locus_tag="VVO74_001601"
     CDS             complement(9514..10350)
                     /locus_tag="VVO74_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5695601.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKLSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10363..10992)
                     /locus_tag="VVO74_001602"
     CDS             complement(10363..10992)
                     /locus_tag="VVO74_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU5695602.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGVGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASELLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11002..11643)
                     /locus_tag="VVO74_001603"
     CDS             complement(11002..11643)
                     /locus_tag="VVO74_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU5695603.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11789..13018)
                     /locus_tag="VVO74_001604"
     CDS             complement(11789..13018)
                     /locus_tag="VVO74_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU5695604.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13008..14174)
                     /locus_tag="VVO74_001605"
     CDS             complement(13008..14174)
                     /locus_tag="VVO74_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU5695605.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFIAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14318..15331
                     /locus_tag="VVO74_001606"
     CDS             14318..15331
                     /locus_tag="VVO74_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU5695606.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15376..15795)
                     /locus_tag="VVO74_001607"
     CDS             complement(15376..15795)
                     /locus_tag="VVO74_001607"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU5695607.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(15806..17212)
                     /gene="atpD"
                     /locus_tag="VVO74_001608"
     CDS             complement(15806..17212)
                     /gene="atpD"
                     /locus_tag="VVO74_001608"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU5695608.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17298..18176)
                     /locus_tag="VVO74_001609"
     CDS             complement(17298..18176)
                     /locus_tag="VVO74_001609"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU5695609.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18192..19697)
                     /locus_tag="VVO74_001610"
     CDS             complement(18192..19697)
                     /locus_tag="VVO74_001610"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU5695610.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19712..20248)
                     /locus_tag="VVO74_001611"
     CDS             complement(19712..20248)
                     /locus_tag="VVO74_001611"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU5695611.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20248..20742)
                     /gene="atpF"
                     /locus_tag="VVO74_001612"
     CDS             complement(20248..20742)
                     /gene="atpF"
                     /locus_tag="VVO74_001612"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU5695612.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(20756..21472)
                     /gene="atpB"
                     /locus_tag="VVO74_001613"
     CDS             complement(20756..21472)
                     /gene="atpB"
                     /locus_tag="VVO74_001613"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU5695613.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21507..21707)
                     /locus_tag="VVO74_001614"
     CDS             complement(21507..21707)
                     /locus_tag="VVO74_001614"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU5695614.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(21782..22790)
                     /locus_tag="VVO74_001615"
                     /pseudo
     CDS             complement(21782..22790)
                     /locus_tag="VVO74_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(23248..23646)
                     /locus_tag="VVO74_001616"
     CDS             complement(23248..23646)
                     /locus_tag="VVO74_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5695615.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFYLQDYLYIRQRYYYQKNL"
BASE COUNT         7081 a         5099 c         4326 g         7337 t
ORIGIN      
        1 actattgtat aatgcttttt gatttgagtc tagtattata ctcttcgaaa atctcttcaa
       61 accgcgtcag cttcgccttg tcgtatagat gttactgact tcgtcagttc tatctacaac
      121 ctaaaaacag tgttttgagc agtctgcagc taactttcta taacaaaatg aaataagaac
      181 aagacaaatc aatcaagaca atcaaatcga tttctaacaa tgttttagaa gtagatgtgt
      241 actattctag tttcaatata ttatagtttg ctctttgatt ttcattgagt attagttcaa
      301 tatctaaaaa aagaaccttg ccaagcaaga ttcttttagt gtctgactta aataattgtt
      361 cttctgggaa ctaaatcgaa ttaagcttcg atttctgtaa ccatacctga accaacagta
      421 cgtccaccct cacggataga gaatgtagta ccttgttcta cggcgattgg gtgaatcaac
      481 tcaacgtcga ttgtcacgtt atcaccaggc attaccattt cagtacctgc tggaagttcg
      541 attgaacctg taacgtcagt agtacggaag tagaattgtg gacggtagtt gttgaagaat
      601 ggagtgtgac gtccaccttc ttctttagta aggatgtaga cttcaccttt gaatttagtg
      661 tgtgggttga ttgaacctgg tttagcgata acttgtccac gttcgatttc atcacgttga
      721 acaccacgaa gaaggacacc tacgttatct ccagcaagac cttcgtcaag ttgtttacgg
      781 aacatttcaa caccagtaac aactgctttt tgagtttctt ctttgatacc aacgatttcg
      841 atttcgtcgt tgactttaac gataccacgg tcgatacgtc ctgaagcaac tgtaccacgt
      901 ccagtgattg agaatacgtc ctcgactgga agaagcaatg gtttgtcagt gtcacgttct
      961 ggttctggga tatactcatc aactgtgttc atcaattcca taacgatgtc ttcgtattta
     1021 gagtcacctt caagagcttt aagtgctgaa ccttggataa ctggaagatc gtcacctggg
     1081 aagtcgtatt ctgacaatag gtcacggatt tccatttcaa ccaattcaag caattcttcg
     1141 tcgtcaacca agtcaacttt gttcatgaag acgataaggt gtttaacacc aacctgacgt
     1201 gaaagaagga tgtgctcacg agtttgtggc attggtccgt cagttgaagc tactacaagg
     1261 atagctccgt ccatttgagc agcaccagtg atcatgtttt taacgtagtc cgcgtgtcct
     1321 ggagcgtcga tgtgagcgta gtgacgtttt tcagtttcgt actcaacgtg cgcagtgttg
     1381 atagtgatac cgcgttcgcg ttcttctgga gcagcatcga tagacgcata gtctttaggt
     1441 tggttaactg atgaaggcaa gcgacgtgcc aaaacagttg tgatagctgc agttagggta
     1501 gttttaccgt ggtcaacgtg tccgatagta ccaatgttaa cgtgtggttt actacgatcg
     1561 tatttttctt ttgccatttg agtaaaagcc tccaataaaa tatattttat agatagacag
     1621 taggcaatac agtctaactt tccttactat tttatcaaat ttcagctaaa ttgcaagtgt
     1681 tttacaacgt ttttgtgaat tattcttggt aaaaatttaa ctaattaata gaaagtacta
     1741 aatagactta tccttcaagg agttttcagc attatccatc cactcacttg ctgaaaatgt
     1801 aaacagtctc tggtttatat agtaaaatga aacaagaata gggcaaatcg atcaggacag
     1861 tcaaatcgat ttctaacaat gttttagaag tagatgtgta ctattctagt ttcaatctac
     1921 tatacaacct caaaactgtg ttttgaacaa cctgcggcta gcttcttagt ttgccctttg
     1981 attttcattg agtataaaat tgcagataaa acgataacaa tcataggact cagcagagtc
     2041 aatgtaggtc gaagaatagc ccccctaatc gcttatttta tagcaaaatg aaatagaaac
     2101 tgaacatttt gttgaggaag gtaaatcaat tcctcacaat gtttgagaaa gaagggggga
     2161 ctattccaac ttcaacccac tataaagcag acttacaaga tagggaaccc atctccgata
     2221 atattccgat aatatatagt agaatgaaaa ctgcacaatt tgattggaga attcaaacca
     2281 atttctaaca atgttttaga aacaagggtc tattatttca actgcaacct actatagccc
     2341 attgaagctg gaatagccca ctgagacttc taaaccactg ctggagagga gtttgtttag
     2401 agtttctttc atttccctaa aaaatcaaaa agagagaacc agtctgatcc tctcttactt
     2461 atagatggtg ctcactcaaa tgttaaagga gctatttctt agagataaag gaatttgaat
     2521 acagctactg ccgcaattgc tgctgcgata ggtgctacta ctggtaccca agaataccac
     2581 cattttgaat cgcctttatg ctcaccaaga actgattttg gaaggaaagc atgaaggaga
     2641 cgtggtccca agtcacgggc tgggttcaag gcaggtcctg taggtcctcc aagtgatgtt
     2701 accaaagcca taacgaggaa tccaagtgcc aagtgagcca cagaaagtcc tgaagcagtg
     2761 tgtggagcca cctgtgcttt aatagccaag tcagaaaaat caactgtttg tcctgcttct
     2821 attgcctttt gtttcatgaa ttgaagcact tcagcaccaa agaagttttt agtcaaacca
     2881 agagctgcaa agaacaaaac aaatgaacca acaaactcat taatcaaacc attgacagtt
     2941 gctgcatagc gactttcttt tgtaccatgg tcaatacttg aaatagttga gaaagttccc
     3001 aagatgttat ttgggttttc agttttcaag tagaatggac ggtatgttgc cacaactaag
     3061 gcttggccaa agatagcccc caagacttgc gcgataatgt aaggtaccac ttgtgcccaa
     3121 gggaaaagac cgctaactgc aagccctaga gtgaaagcag ggttgatgtg attcccagat
     3181 acgttaccaa acatcaaggc tgggatcata acccccatac cataaccaac agcgatgacg
     3241 atccagccac tttggtgacc tttcgtacct ttaagttcaa cgttggcaac tgcaccattc
     3301 ccaagaatga tcaaaatggc agttcccaaa aattcagtgg catacttcag tgcccatgtg
     3361 aaatccattt gctagattct ccttaaaatt ttttagatat tccttatttt atcaattttt
     3421 accctattta gcaactgatt tctggaaata tttttaaaaa aataggattc atagtttccc
     3481 agttcaacgg acttgtaagc gtttttattc ttcacgaaag acctcgttct caaaaccagg
     3541 aaaaaagccc acatctgtga gcttttcctg gttcctagat tctaaaatct attatttttc
     3601 atcttctttt ttcttgaaga atcctaatac tagactagct aacaaggtca tgataccagc
     3661 actagccaag gtagcattag cttctgtacc tgtgtttgac aatccctctc tcttacctgt
     3721 ctcataagtc ggaacttctg ggtctagatt cactggagtt tcagtttttg gagtacctgg
     3781 ttctggagtt ggctctggta ttggagtctc ttgatttggt agttctgggt ttggtgtcgg
     3841 aacacttgga tgctctggat ttggttgtgg gattggtttt tctggagttg gtttatctgg
     3901 tgttgataaa cggtcatacc ttaccgttat ttctttatca ctagagtctg acgtaacttc
     3961 ttgtgattca actgttggaa tatctggagc tttgtacttg tcaatcttac cagatacaac
     4021 ctcgtcccag tttcctgttg tccattcacc gtaggttaca actcccgtga ccttgttctc
     4081 agtttttgta cggcttaagg ttacaggttg aacaacatct tcttttacat tttggttcgt
     4141 aactttatca acgtaatgaa tgatacgcgt tatagtcttc gtctcagtag aggttgctgt
     4201 tttgggaacc actgtttcct caacattcta acggtagtaa tagtcaactg ttgcaccgtc
     4261 ttctggtacg catttgcagg agttgctacc aaggtgtatg ttgttttcct tgtgataact
     4321 cggttttctt tgtcctcagt tgttgttttc ccttcaatag tttttgattc tgtggtatac
     4381 tcagaaccta tcgctaaatc agcttttata acagactctg ccaacttctc ttggctacct
     4441 tctttatagt aattggctgt tactgtaaca gtggttggcg cttcgctttc tctataaact
     4501 aaggtcactg ttctaccttc gcttacaata ttcccagtta aacttgcaga atttgtatct
     4561 acttctttaa aagtataata ttttccgtca gtagtagtca tgctactgag ttttttatct
     4621 gtgacattgt agctggtacc aatcagttgt tttttattgg taatgtaggt tccgtcactt
     4681 tctttttctc caattccagt atcatttttc aatgatagca aacgcccttg ttcatcaaca
     4741 tagcgaactt tcacattttc tgagattagt tctgccaatt ctgaggtttt tttctttttc
     4801 ttgatttctt cggttatttt ccctttctct tcttcgggaa tatttagttt tggaatgatt
     4861 ttttcaacaa cggttcgtga tggttccaca gtatcttgga tgactgaaaa gtcagctaga
     4921 attgggagat tatactgaac acggtgactt tgagtgttta ctcctactct ttcattattc
     4981 tctgaaaata cttgtacggt ataagaaaca acatcttttc ctaatagaac atccccagta
     5041 gagaaatagc cgccttttcc tagtttgcta tctccagagc ccacttcttt cctaatctta
     5101 tcagatagtt ttttaccagt cagtacattc gttcgcacaa tccctttgtc tacccctaca
     5161 aagtgggaga actttttgaa ctcttcagaa ccagatctag cccaaccatt attaagggca
     5221 tttgcttttg tatttgtatt ctctctcaaa agtttggcga ttagaattat attcatcggc
     5281 acttagagtt gctgctatat ctgactcttg aataccaact tccttactac catttctagc
     5341 ggcagtatat gtgtatttat ctgtttctac ttctagctga ttatccttaa catgataggt
     5401 aattttctcc tggtataaga gtcttcagta gtttatatgc tctgtcatca tctttagctt
     5461 tagaagcagc tgagtttagc caagttgggg tattaggagt atctttatca gcctgtttca
     5521 agacattatt caagtcattt gctagcctat tggttgtcct cactgtgaaa gttttcttcc
     5581 agtctgaacc acttttatta gacttagata tgctcatgaa atcctggtca acattcaaca
     5641 caatatcgcc ttgtttttta gcatcttccg ttgcttctgc ttcaaattga tcatggagtt
     5701 tttgttgctc tggtgtatag tttttttatt tacacgattt aatgtactat tttttatttt
     5761 agtattaaga actccattaa tacgattttt aaactctgct tcaaaaaatc ccttaatttg
     5821 ttggtgcgca agttcaacat tcaaaccttt tttatacaag tcttcattct gaacgatttc
     5881 ggctacacgg tgaatggttt gattgtatac cgtcttctct taaccagcag tatccttagt
     5941 tttaatgact actcgatagg ttcctttaga accgttatag tcatctagtt ttaaaaaagc
     6001 attccaaaca ttcaaaaata gttggaactt cccttaataa atccgtcact ttctttttca
     6061 agatagccca agcttgctca ataggattca aatccggtga ataaggtggt agaggtaaga
     6121 aaaagtgttt atcttggatg cagagttcat ccaaaatgtt cttgggatga aaaccagcat
     6181 tgcccatgac aataacatga ggtgtcttca aagcaggtag gagttgcgtt ttgaaccact
     6241 ccacaaagaa atcgcttgtc atgcttttct tgtaaatcat gggagctata aactctccgt
     6301 ctacttgtcc tgcaacaatt gaaattcgct caaaacgacg tccgctaatc ttttcataga
     6361 ctttctcccc tctaggagcc cctgcataag gacgatagag atagcggtcg attcctgttt
     6421 catcaatata aacaggtgct aggtgcttta aactattaaa attcttaaga aataaggcta
     6481 cttttctggg tcttgttcct taaagctcgt catctttttt taaagtgacc ttaatctgct
     6541 ttaaagctgc ccatactgaa ggaacagcac aatcaaaatg tgccgcaatt tcccgtaaaa
     6601 aagcatctgg atgagcctct acaaaggctt tcaattcctc taaaggaatc tttcggtttt
     6661 tgacgactcg ctttttcctc tctatgtgtt cttgttcacg tctttctttt cccacgtgaa
     6721 gagagttctg acgccaacac caaaaaactt ggctgcctcg acatggctgt gcccctcttt
     6781 gatgtaatct aatgctcgct gtttaaaatc agtactatat gccatagctt tattataata
     6841 tgcttgttta aaactaagta actatatcaa tgttttgtta tgagaagact tacttttttt
     6901 actgaaattg aatttttcct agcctaaaca tcatataacc ccaaaattca atctgacctg
     6961 gtttgaagag attttcgaag cagataaggt tttactaaaa ctaaaaaaaa tgatataatc
     7021 aaactgatta aatgttttaa aaataaagga gaatttgaat gtcttaccaa gaaaattacc
     7081 agaaatgggt tgattttgtg gagcttcctg actaccttcg tcaagatttg gaaaatatgg
     7141 acgaaaaaac taaggaagat gccttctata caaatcttga atttggtact gcaggtatgc
     7201 gtggcttggt tggtgctggt acaaaccgta tcaacatcta cgttgttcgc caagctactg
     7261 aaggattggc tcgtttgatt gagtcaaaag gtggaaacga gaaagaacgc ggtgtagcaa
     7321 ttgcctacga tagccgtcac ttctcacctg agtttgcctt tgaatctgcg gcagttcttg
     7381 ctaaacacgg catcaaatct tacgtatttg aaagccttcg tccaactcca gaactatcat
     7441 ttgcagttcg tcatctcaac tgtttcgcag gtatcatggt cacagccagc cacaaccctg
     7501 ctccatttaa cggttacaag gtttacggtg aagacggtgg acaaatgcct ccacacgatg
     7561 cggacgcttt gactacttat atccgtgcaa tcgaaaaccc atttgcagtt gaagttgctg
     7621 atgtggaaac tgaaaaagct tctggcttga ttgaagttat cggcgaagct gttgacatag
     7681 aataccttaa agaggttaag gacataaaca tcaacccagc cttgattgaa gaatttggta
     7741 aagacatgaa gattgtctac acaccacttc atggtactgg tgaaatgttg gctcgtcgtg
     7801 ctcttgccca agcaggattt gactctgttc aagttgttga agcgcaagca actgctgacc
     7861 cagacttctc aactgtaaca tctccaaacc cagaaagcca agcagccttt gcccttgctg
     7921 aagaacttgg tcgtcaagtt ggtgcagatg ttcttgtcgc aactgaccca gacgctgacc
     7981 gtgttggtgt tgaagttctt caaaaagatg gtagctacct caacctttca ggtaaccaaa
     8041 tcggtgctat catggctaaa tacatcttgg aagctcacaa aaacgctgga actcttcctg
     8101 aaaatgccgc tctctgcaaa tctatcgttt caactgactt ggtaacgaag attgctgaaa
     8161 gctacggcgc aactatgttc aacgtcttga caggtttcaa atttatcgct gaaaaaatcc
     8221 aagaattcga agaaaaacac aaccacactt acatgatggg atttgaagaa agcttcggtt
     8281 acttgattaa accatttgta cgtgataaag atgccatcca agccgttctt gtcgttgctg
     8341 aacttgctgc ctactaccgt tctcgtggtt tgacacttgc tgacggtatc gaagaaatct
     8401 ataaagaata tggctactac gcagaaaaaa caatctctgt tactctttca ggtgtcgatg
     8461 gtgctgaaca aatcaaagcg attatggcta aattccgcaa caatgctcca acagaatgga
     8521 acgcaacagc tatcactgtc gtagaagact tcaaggcaca aactgctact gttgctgacg
     8581 gtactgttac aaacttgaca actcctccaa gtgatgtgtt gaaatacaca cttgctgacg
     8641 gttcatggat tgccgttcgc ccttcaggta cagaaccaaa aatcaagttc tacattgcag
     8701 ttgtagggga aaccaacgaa gaatcacaag ctaagattgc taacatcgaa gcagaaatca
     8761 atgcatttgt aaaataaaga cctataaaag atgagaccaa ccaacctcat cttttttcgt
     8821 atcaaatcta agcaatttta gaaactttat ggcatactag acttatcaat gaaagcgagg
     8881 taatctcatg gaacaatttt tagataacat caaagacctt gaagtcacta cagttgtgcg
     8941 tgcgcaagaa gctcttgata aaaaagaaac tgcaaccttc tttatcggtc gcaaaacttg
     9001 cccttactgc cgtaaatttg caggtacatt gtcaggtgtc gtagctgaaa ccaaagctca
     9061 catttacttc atcaatagtg aagaaccaag ccaactcaat gatttgcaag cattccgctc
     9121 acgttatgga atcccaactg taccaggttt tattcatatt acagatggac aaatcaacgt
     9181 ccgttgcgac tcttcaatgt cagcacaaga aatcaaagat ttcgcaggat tgtaaaaaat
     9241 cagctaacaa gtcttaaaat cacaaaaacg cataatgtaa ggtgcaaaaa ccttgatatt
     9301 atgcgtttta ttgttcctaa aacagttaca tcagtatttc attacagaac attttaattt
     9361 tggaagtcaa atcaattttt aacaatgttt tagaaatcac agtgggctat tccatattca
     9421 attatccaga ttcaatcgct attatcgttt tcctagatta caaaaaaaac tacgttttgc
     9481 taatcaaaac gtagtctcag ccactatttt atcttactgt ccttctttta cttctttggt
     9541 tgctacatct tctccaaacc atttttggct gatttcttgg aacttgccgt ccttgtaaag
     9601 actagaaaaa gcttcattta tcttcttaac caaggttgta tcttccttac gggctccaac
     9661 cgcaaaagct tctgtttcta gtccaactgt aaagacatta taatcgttta aaacaccttc
     9721 tgcttctaaa taatagtttg cataaacacg gtcaatcaat agaccatcaa ttcgatcgtt
     9781 tttcaaatca atcaaggctt cattaaaggt ttggtattga ttcgcttcct tattagcgac
     9841 aatattcttc aaaagttctg gatttgcttc aaagtccgca taaccagatg aaccagcttg
     9901 agctcctaat gtctttccag tcatatcctt tgcagtcgtg ataccagata atttcttcgt
     9961 aaccaatacc tgctcattct tcatatatga gttactgaaa gccacctttt cacggcgttc
    10021 gtctgtagcg gaatagccat tccaaatcag atcaatcgtt ccttttgtca attcagcttc
    10081 tttcaaatcc caatcaatcg gttgccaatt taccgtgatt ccgtattttt caaaaacagc
    10141 tgtagctaaa tcaatatcaa atcctgcata agaaccatct ttctgagcaa atcccattgg
    10201 aacaaaagta ctatcaaatc caatagtaat agacttgtta gactggtact ttgaccaatt
    10261 atctccacta gtttcgctag aatttttccc acaagctact aagaacaaag cagtcatcag
    10321 actgactaat acaagcatcc attttttcat ccatttttcc tcctatttag gttctacttt
    10381 caataataca tctgcgatat tttcagcaaa ctgcaaatca tgggtaacca caatctgggt
    10441 catcccaagt tccctatttt gcaagattag cttctccact tccaaacgta attctggatc
    10501 cagggcagaa gttggttcat cgtagccaat gatttctggg tcaatcatca tagcacgcgc
    10561 caaagccact cgctgctttt gcccaccaga tagtgagaaa ggataggcct ctgcgtgtcc
    10621 tcctagtcct aactgttcca agagttcact cgccttcttc tcagcctctt cctgcttcat
    10681 tcccatggtc ttcacaggcg ataaagtcaa attttccaga actgatagat gaggaaatag
    10741 ttgaaaatct tggaagacaa atcccagtag gttgcgcttc tgcaattcat ccagctctaa
    10801 aggttgtcca ttataaaaga tttgccctga atcaatggtt tcaagacctg caagcatacg
    10861 taaaagagtt gtcttaccta caccagaagg tccaacgata gccaggattt gcttttcagg
    10921 aatacttaga ctgaaattag acaggatttg tttgtctcca aagactttat tgatatttcg
    10981 taattctaac atggcagcct cctatctata ataactatac ttcttctcaa cttttttgga
    11041 aataattgtc acaatcccaa tcaaaatcaa ataaatggct cctgccaaga acataggaac
    11101 cagactagca tcgcggttag cagctgttcg actagccaag ataaggtctg aaattccgag
    11161 agcatagacc aaagaagtat ccttgaccaa actcataact tcattaaaga cactaggaag
    11221 aacgatcttg gtcacttggg gcaagataat atagcgcact ctgtcaaaag ggctaaactt
    11281 caagaccttg gcagcctcat actgtcctct tggaatagtg tcaattcccc cacggaaaat
    11341 ttctgcaaag taagccgcat aattcaaaac aaaggcaata atagctgcag gaaggcggtc
    11401 taaacgaatc ccaatacttg ggagcacata atagataaaa atcagttgca agagtaaggg
    11461 ggttcctcgc ataacccaga tgtaaatgtt aatcagataa tggaggggct tccaatggac
    11521 ttgcaaggca aaggcaatca aaacgcccaa gggaatcgaa aatagcaaga ccagtgcaaa
    11581 gacctgtaca gtcgtgctcg caccattcag taaactcggt aatatctcaa ataaataaga
    11641 catactgcac ctcctaaaag taattgttcc tattatagca tgaataaaca agattaccaa
    11701 gtatttttgt aaaaagattc taccatatac aaataaaaac cgtagctatc aaaagagata
    11761 aactacagtt ctatatgttt aaacattctt acaatctctc aaacagttct tgcatttgca
    11821 catcatctgg aaccagtttt aagtaagtgt gagcatggac ttttgcttct tcaaaatgtc
    11881 ccaattcacg caagagatag atatagtgtt ccagaaattc tggattgtcc ttcaaatctc
    11941 ctgtcaactc ttgataatgc tcataagcag tatccaaatc gtccatttct tgataagaac
    12001 gagcaatcat ccacttggtc aaaagatttt ctggctcctc actctgcaag tctagaatat
    12061 cctcataacg ctcctgctcc agataaatag tggctaaacg aagcaagatt tcttctgtat
    12121 cctcagcgtc ttcttttgca gtaaggagat aattttctgc accactagca tcatgcaatt
    12181 cataagaaaa ttgtgaagca gctagcaaga ggcgagtttc aaagggattt ttctctaatc
    12241 cttgcttagc gatacgcagg gcttcttgaa cttgatgttc cttatgtaaa gcctgactgt
    12301 acccatactc atagccttca aagtcaggag aaatggtatc aagctgctta aagtagaggg
    12361 tggctttttg atattcttct tgatcaaaat aaagactggc caactcaaaa gctgttaagt
    12421 catcgtattc taactccagg gctttttcta aaaactcagt agccgtttca aatttcccta
    12481 actgagcata ggcaaagcca attcgttgat aggtggaaat gcccgtttgc tcataaatcg
    12541 agcgattatc taactgggca taggcttgaa tagccgcttg gtaattttcc aactcactat
    12601 ccaactctgc caaacccaat atcaagagag aatcctctga gtaggtcaag gcctccaata
    12661 atttctcacg tgccacatct gtcaaacctt ccagctggta aaggtctgcc ttcagagcca
    12721 aagacgagac ataccagtca ctgtcagctt ggatttcctc aagataggta aaggcttctt
    12781 ctatttgacc atcctcgcta gcaattgcag ctagattaag atgaacctct ggaaaatcct
    12841 ctacaatttt caggtaaatt tccttggcct gaggatagaa accaatccct tcaagataag
    12901 ttgccaactc atacagaaga tcacttgaat cattttctaa agctttggcg aaataatgct
    12961 cagccttagt taaatcttgc tcctccaaag cctgtaacat ctgttgacta ttgttcactc
    13021 ttgacttcct caccctctaa ttcatataga ccactgacta ccttatacca ttcgaaaatg
    13081 gctgaaatga caaccttagc agaggcataa accggaatac caagtaaaac tccccagata
    13141 ccaaacatag atcctgaagt taacaaaaca aagagaacat taataggatg gatgtttaat
    13201 tgacttccca aaatcaatgg agagacaaaa cggccttcaa tagtttgttc tacaataaag
    13261 acaatcacta ctttcaaaag catgactgga ccagcaatca aacccaatac tagggcagga
    13321 agcatggcta gaaagctacc aagataaggg accagattta aaataccagc agtaaccccc
    13381 agcgtaaccg catagcgtag accaataatc ttgaagaaga tgataaacat tactgctaca
    13441 ataatagcca ctgtcacttg ccctcgaaca tagttggaca actgttgatt cacatctgat
    13501 agaacttgtc caacaggttc cttcaatttt cttggaatga attgggtcaa atagttacgc
    13561 aagcctttcc catcacgcaa gagataaaag agcatgaaag gaacgataat caaggcaaca
    13621 atcacttgag aagctccgct aataaaggca ctcacccagt tgactgcctg agatgaaacc
    13681 ttacttgcca aaactgtagc ctggctagaa aaattggtca aaacttgctc taattgaggt
    13741 ctgaaatcat ctggcaggtg ctgggctacc aatccattaa caatcctatc tatatcttct
    13801 aagtaaacag gaacgtttct tgcaaaggtc aaaacctgac gttgcagatt tggaatggcg
    13861 actgccaagc cccaaatgat aaagagagcg atgataacaa agacaatagt gatagctata
    13921 acacgattaa ccttatgctt ctccatccaa tcaacaatag gattcaacaa ataatataac
    13981 aaaccagaca aaatgactgg caacatcaca actgctataa agtctaaaac aggtgaaaat
    14041 agaaaactaa tcttacttaa aataaaaaga ttcaatccca ataataaggt tactaaaaat
    14101 accgtaattg ccttgttatc taaaaaccac ttgaaaaacc aagataggct aaaatgtttc
    14161 tctttttgct ccataaatac ttcctttcta ttgttctctc attataccat ttttgaaaca
    14221 aaataactct tttttaaagt gcttacatct aattgaatgt ctttaatttg cttgtttttg
    14281 tgatataata gtcttatctt tacacagagg tatagtaatg aaagaaactg tttattttgg
    14341 aacttataca cgtcgtactt ctcaagggat ttacaaggca gactttgata cagaaactgg
    14401 tcagctttca aatctagaac tttttgcagc tgagccaagt ccaacctacc ttgcctttga
    14461 ccagcaccaa catttataca ctgttggtag ccaagacgat aaggggggaa ttgcagccta
    14521 tcaaactgac gggactgtgt taaatcatgt tgttgaagaa ggagctcccc actgttatgt
    14581 tgctgtcgat gaaaagcgtg atttggttta cgcagccaac tatcacaagg gacaagtcct
    14641 tgtttataaa cgccaggaag atggtagtct tctacttagt gatatggatc aacacagtgg
    14701 ccaaggtcca catgaaaatc aagcttcccc ccatgttcac tatacagatt taacacctga
    14761 ccactatcta gtgacctgcg acttgggaac tgaccaagtc atcacctatg acctcgatca
    14821 agaaggaaaa ttatctaagc tctataccta tcacagcaag ccaggagcag gctcacgcca
    14881 tatcattttc cataaccact ataaaatcgc ttatctcatt tgtgaactca atagtactat
    14941 cgaagtttta atctacgatg gcgttggcga atttgaacgt atgcaggtta tttcaacttt
    15001 accagaagct tacgaaggct ttaatggaac cgctgctatt catctctcta aagacggtaa
    15061 atacctctac gcttctaacc gtggccatga ttctatcgca gtatatacca tccttgcgga
    15121 cggtagctta gagttattag aaatcgttcc aacgcatggt cagactccac gtgattttga
    15181 tttgacaccc gaccaaaaat ttctcattgt tgtccatcaa gactctgaca atgcaactgt
    15241 ctttaaacgt aattgtgaca atggtcgtct agcagaactc tccaacgact tccatgttcc
    15301 cgaagcagtc tgcatccgtt ttgctcctta aaacaccata aaaaatgaac ttggtatttt
    15361 caagttcatt ttttcttata gtctatttcc gacattaata cggttaatag cacgttgcaa
    15421 agcaatctta gcacgacgtt cttggtcaat caaatgtttg tcttgtgctt cttcaattgc
    15481 acgttctgca cgaagtttgg cacgttctgc acgactgata tcgatatcac gagcacgttc
    15541 tgcagagtca gcgacgattg tgatcatatc attggcaatt tcaataacgc caccgtttac
    15601 tgcaatccag ttcacgtgat ctttatcatc gatacgtttt acctttactt catcaactgc
    15661 taaaaccgca atcatatttt catgtcgtgg caagatcccc atctcaccat ccagagttcg
    15721 aaccgataca tagctggcat ggtgatcata gacgagacca tctggtgtca cgatctggac
    15781 agttaactga gccatagatc acctcttaaa atcccatttt ttcagctttt gcaatcacat
    15841 cttcgataga acctacacca cggaaggcat cttctggcaa gtggtcgtat ttaccatcaa
    15901 ggatttcctt aaagccacgt acagtttcag caactggaac ataagaacct ggctgaccag
    15961 taaattgttc cgcaacgttg aagttttgtg acaagaagaa ctggatacga cgggcgcgag
    16021 caaccaaggt cttttcttca tcagaaagct catccatacc aaggatagca atgatatctt
    16081 gcaattcatg gtaacgttga aggacacgtt ttacttcagc agcaactgca tagtgctctt
    16141 ctccaacgat ttcaggtgcc aaggcacgtg agcttgaagc aagtgggtca acggctgggt
    16201 agatacccaa ttgtaccaac ttacgttcca agtttgttgt tgaatccaag tgagcgaagg
    16261 ctgttgctgg cgctgggtca gtatagtcat ccgctggcac atagatagcc tggatagagg
    16321 ttacagaacc cttcttggtt gatgtgatac gttcttgcaa ttgacccatt tccgtagcaa
    16381 gtgttggttg gtaaccaacg gctgatggca tacgacccaa aagggcagat acttctgaac
    16441 cagcctgagt gaaacggaag atattatcga taaagagaag cacgtcttgg ccttccacat
    16501 cacggaagta ttcagcgatt gtcaaaccag taagggcaac acgcatacgt gctcctggtg
    16561 gctcattcat ctgaccaaag accatggctg ttttctcgat aacgcctgat tctttcattt
    16621 cccagtaaag gtcattcccc tcacgagtac gttccccaac accagtaaat actgaaatac
    16681 caccgtgctc ttgggcaatg ttgtgaatca attcttggat taagacggtt ttaccaactc
    16741 cggcaccacc gaaaagtcca actttaccac ctttaaggta aggggcaaga aggtcaataa
    16801 ccttgatccc tgtttcaagg atttcagaag aggtagacaa ctcatcaaaa gttggagctt
    16861 ttttatgaat tggctgacgc tctgcgtctt ctgtaaaagg agcttccaaa tcaatggtat
    16921 ctcccaaaac gttgaagaca cgtcccaaag tttctttacc tactggtaca gagattggac
    16981 gacctgtgtc caatacttcc attccacgag tcaacccatc tgttgattcc atggcgatag
    17041 tacgaaccat accatctcct aactccaagg ctacttcaag gacgattttt gtttttcttt
    17101 cgtcattttt gtagacgaca agtgcattgt taatctcagg aagtttttcc cctgctgcaa
    17161 acaaaacgtc tacaacggga ccgataacct gagcaatttt acctgaactc atctccttct
    17221 cctattctat ataagatact gtcggttcct agctcaacta ggtcctaagt tcattttcat
    17281 acgagctgga ctagagccta ttctaaggca ctagcacctg ctacgatttc tgtaatttct
    17341 tgtgtaatcg ccgcctgtct ggcacggtta tactgaattg tcaaatcatt gatgactttc
    17401 ttagcattat ctgtcgctgt ttgcatggct gtcatacccg cagcattctc agctgtcttg
    17461 gcatcgataa tggcaccgta aatcatactt tctgcaaact gaggcaacaa ctgctccaga
    17521 atttcttctc ggctggtttc caattcaaaa gtcaagctgt actcttcatc cgcttcattt
    17581 ggatccaagt caacaatcgg aagcatttgt tccacacgca tttgactggt tagcgtattg
    17641 acatggtggt tgtagcaaac ataaagctca tcaaagagtt cattttggta catttcaaca
    17701 gtttttgaaa taatcttacg aacttgatca aagctaggtt ggtctgccaa gccacgtaat
    17761 tcataaagtg gttgaatacc gcgagcctta aagaaatcag ctcccatccc accgatacag
    17821 atcatttcaa aacctttacc gtctgggtgg tattcttctt tcaactccat aacagctttc
    17881 aaaatagagg aattataacc tccaaccaaa ccgcggtctg aagtgataac gatatagcct
    17941 gtcttcttca cagaacggct aatcaacatc ggattagttg aagcaccagc tccattacca
    18001 tgaaggatat ctgtcaaaag tttacgcact ttctgagcgt aaacttggaa gttgcgagca
    18061 gcttcttcag agcgacctaa cttagcagcc gataccattt gcatggcatt agtgatttga
    18121 ctcgtatttt ttgttgaggc gatttttgtt ttaatatcat ttagagacac tgccatctga
    18181 cacctctatt cttattggaa gctagattga ttgagaaact ctgtaatcgc agcatccaag
    18241 actgcttctt ctggcaagtc ttttgtatca cgaatggttt ccaaaatctc tggatgttga
    18301 gcatcaaaga aggcatggaa ctcttcctcg aaacgaacaa tatcatctac tggaacagta
    18361 tccaagaaac catgtgtcaa agcataaaga atggttactt gtttctcaac aggtaatggt
    18421 ttgtgaacag gttgtttcaa gacctcaacg gtacgacgtc cacggttcaa cttagcctgt
    18481 gttgctgcgt ccaagtcaga accaaactta gtaaaggctt ccaactcacg gtatgaagca
    18541 aggtcgatac gaagtgtacc agcaaccttc ttcatggctt tgatttgtgc agaaccacct
    18601 acacgagata cagatgaacc cgcatcgatg gctggacgaa tacctgcatt gaagaggcca
    18661 tcgccaagga agatttgtcc atcagtgata gaaatcacgt tggttgcgat ataggctgag
    18721 atatctcctg cttgtgtctc gataaatggt agggctgtaa ttgatccacc accaagttca
    18781 tcagaaactt tagctgagcg ctcaagcaaa cggctgtgga gatagaaaac atcccctggg
    18841 aaggcttcac gacctggagg acgacgaagc aagagcgata gttcacgata agctaccgct
    18901 tgttttgata gatcatcgta tacaatcaaa acatgcttac cttgatacat aaattcttcc
    18961 gccatagcaa ccccagtata aggagctagg aagagcaatg gagatggttg tgaagcagag
    19021 gctgtcacaa cgattgtgta gtccaaggca ccgtactgac gaagtgtttc tacttgcgta
    19081 cgaactgttg attctttttg tccaatcgcg acgtagatac agatcatatc ttgatctttt
    19141 tggttcaaga ttgtatcaat cgcaatggtt gttttccctg tctgacggtc accgataatc
    19201 aactcacgtt gaccacgacc aatcggtaca agggcgtcaa tagctttcaa accagtttgc
    19261 aatggttctg aaacagactt acgttgcata acaccaggag ctggtgcttc tactggacga
    19321 gttttatcag tgtggatttc tccaagaccg tcaactggac gaccaagcgg atccacaaca
    19381 cgaccaatca gactttcacc tacagggact tccatgattt tccctgtacg gcggattgta
    19441 tcgccttcac ggatatctgt aaagtcacct aggatgataa taccaacgtc tgttgactcc
    19501 aagttttgag ccataccata agagccgttt tcaaaattca acaactctcc actcatgaca
    19561 ttttcaaggc catgagcacg cgcgataccg tccccgatat aggttacaac acctgtttca
    19621 gtcacatcaa aattgggttt gaaattttca atttgttgct taattaaagc gctgatttct
    19681 tgtgcgttaa ttgccaaaag aacaccactt tctatttcaa attttcttta acaactttaa
    19741 gttgttgttt aatactcaca tcaattgtct tgtgattggc aaaaatgaca aaaccaccaa
    19801 tgagactttc atcgatttgt tcttttacac tccttacttt cagagacatt tttttctcaa
    19861 tcaaagggag caaacgagtc ttctgttcat cagttagagg atgagcagac gtaatcgtca
    19921 cttcaaatcg atttgtttct ttttcaagtc ggttcaagca atctacaagc acatcataaa
    19981 aaagatttgc tctgtgattg taggccagaa cctggataaa gttttgtaat aaaggcgaca
    20041 cagaatcttg gaaaaaagca attgtttttt ccttatccga ctcgtctact gccacttgtt
    20101 ttaaaaaaga aggcagacct gttttttcaa caacttgctt gatttgagtc aagtctgaaa
    20161 agatacggtc ttcttctcct ttttcaagta ccaattggac aaaaggcatg ctgtattttt
    20221 caattacctt tactgttttc ttgtccatta agcttctcct agctgatcga tatactgatc
    20281 aatgagtgct ttatgggcat gactgtcaag gttttgtgag atgattttac cagctaagct
    20341 gatggtcaaa tctgcgacct cacccttaac actctgtaaa gcttctactt tattttgagc
    20401 aatttcttga ttggcttttt cttttaagtg tcctgcttct agtttagcat ctgctaagat
    20461 attagcctta ctttgctcag ctgtttcctt tgcattttca atgattgtct tagcttcttt
    20521 acggctacca gccaattcat cttcgcgttt ttgagccaat acttctgctt tttgacgggc
    20581 ttcttcagct ctgtcaatat ctgaagcaat tttttcagct ctttcttcga aaatgcctgt
    20641 aatattagac catgcaaatt ttttaatcaa gactagcaaa agaataaaag agccagtgat
    20701 taaaataaaa ttaccaatta attcacctac tgttacgtgc atcagttact cctttctatt
    20761 cctcttcaat attaatctta ttccctaaat acacagatgt caaaagagta aaaacataag
    20821 cttggatgca ggaaataaag acagaaaatg cagtccaagc caaattagct ccaaaggcta
    20881 ctggatacca ataaatagct tggtgggaaa gaagaagtaa caaactcgtc atgacctctc
    20941 ctgcaaagat attcccaaaa atccgcaaag ccaaagataa gaagtttgta aattcttcca
    21001 agatattcat cggtatgaca aaaacaggac tcataaaaga ttttatactt tttttaaatc
    21061 cacgacgacg aacgctttct atatgtgtca acaaaatgac aagaaaagat aaggttaagt
    21121 catactgtaa attagcggtt ggcgaactcc accagttagt cccatcgatc gtttgaagct
    21181 ttgtcattaa gccaaggtta ttggcaatca ccatgaaaag gaataaacaa aggaaaaaga
    21241 gtgagtaatc tttcatgtag cgcgaaccaa tgttaggttc tgtaaatcca ataacaaagt
    21301 catagacata ctcaagtaca ttttgctttc ctttgggttt caaggtcata ttgcggcttg
    21361 cccaataaat aaagacaaaa ataactccca caatcaacaa agtcatggct aacatagtca
    21421 gattgaagat aacaggacca atagagatga ttggattaat actttcttcc atctaaaatc
    21481 ctcccttttc ttctcgttcc atgtatttat ttgataataa atgagaagac aagagttaca
    21541 aagaaagttc cttcaataaa ggcaacacct aaaaacatca aactacgaaa ctcagaaagc
    21601 atatctggtt ggcgtgctac tgatttaaac agtccattca tcaataaacc ttcaccgaca
    21661 gatacgccca tacaggcaat acataagcct aaaaatgtta aattcataac aaattctcct
    21721 ttaaaataaa atttacttac ttagtgtagt cctaaaattt aaatttgtca acttttaacc
    21781 gctattggaa gcgtttaata aaaattattt ccattttgct aaatttcaag ttcaagttag
    21841 ccatccagaa gtcttctctg ggtgacttgt agtccaagca ttttttagga tagttgttaa
    21901 tccacttttc gatgaatgcg acttctttgg gagtcatttt cttggttccc ttaggtaacc
    21961 atctacgaat gagcctgttg tgattctcat tagttcccct ttcccaagag gcataggggt
    22021 gcgcataata gatgtgctcc tcagaaaata catcaaacaa gcgattgaat tccgttccat
    22081 tatctgccgt gatggaaaga atcttgtgtt gttttaagat gagttttaga gcctgattga
    22141 ccacctcagc acttttattt ggaatcaatc ggatgatctg atgtctactc tttcgatccg
    22201 tcaagacaag caagcagtag tttttcgctc tcgtaagtag aaccgtatca atctcataat
    22261 gcccattctc caagcgaaga ttgatagctt cagaccgctg ttcgatggat tgaccagcag
    22321 gtttaaagtt ggtgctagcc tgtttcttaa gcgcttttcc ttttctaggg taaagcagat
    22381 cctgtttgct taaccccaat tttccatgat gaatccaata gtaaatggtt gaaattccca
    22441 cgttaacccc tttagccatc accatcattt caggcgaaaa tttttggtta tgatagtgga
    22501 gaatcttttc ctttagttcc ttggtcaagc ttgatttctt gaccgagcgc ttgcgattgt
    22561 tttcataaga ctgttgagca tagtcggcag aataaacctc tttgaagcgc ccttttccaa
    22621 gacattgtcg gactgtccca cgcttgattt cagtgtggat agtttgagga acttttccaa
    22681 gcagagaggc aatttctcta tttgatttcc ccttcttttt tccatctttc gattaagcga
    22741 cggctatcga ttgtcaaatg ttcgcctttt gtagtataat ggttttgcat ctctgtgcct
    22801 ttcttgtgtt tgtggttgaa caacaagtat aacacagagg tgttttctta tgcctacaag
    22861 agctttcatt atttccattt tctttcggat ttcactctat tctgaaaaac ttgtgtatat
    22921 ttactgaagc tagcaagtct tacctgtaaa tttaatgaaa gcaacacaaa atccgagagg
    22981 ggaatctcgg attaatgtca atttaaaaag atagagagtt tttagtttaa ataaattgtt
    23041 ttaaaatatc aacaacatca cttcttttct taacctgata agccttgatt cctaattttg
    23101 gagctacgat tatattgtcc tcaatatcgt ctagaaagac acaatttcta ggttataact
    23161 ggtatttatc gatagttact catatacatc agtccacctc catacttatg tgcgagcctc
    23221 tctttgtatt atacctccat actcacctta cagattcttt tggtaataat atctttgcct
    23281 aatgtagaga tagtcttgca aataaaaaac ttccttgtag ccatgtttct gataaaagtc
    23341 cggtgcctgg aactgataag tattgacaaa ggcaaaacaa caatttcgat tcttagcttc
    23401 actttctgcc tgttgcaata gttttgaacc gattccttgc cctcgcagtt cctcttttac
    23461 aaacaaatac tcgatttcta gccaatttcc aaaagtctct gctatcaaac ccgcaaggag
    23521 attgcccttt tcatcttcga cataaagatt aagtggctca ctttcagcct cttccctttt
    23581 tgaacggtta taaacacgaa tcagattccc tatttcttgc gatttatgtg attccttatt
    23641 ttccaatcta aagtataatg aaatgaaata aaacatgcgc aaatcgatta aggaatttaa
    23701 tctaatttct aataatgtct tagaaatcaa agtttactat tttaacttca atgcactata
    23761 catctaatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gttgctcaaa
    23821 acactgtttt gaggttgtag ata
//
LOCUS       DAVHKZ010000033        22112 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000033 DAVHKZ010000000
VERSION     DAVHKZ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22112
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.033"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(1..2316)
                     /locus_tag="VVO74_001617"
                     /pseudo
     CDS             complement(1..2316)
                     /locus_tag="VVO74_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458145.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
     gene            complement(2395..2922)
                     /locus_tag="VVO74_001618"
     CDS             complement(2395..2922)
                     /locus_tag="VVO74_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU5695616.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(3005..4336)
                     /gene="hk06"
                     /locus_tag="VVO74_001619"
     CDS             complement(3005..4336)
                     /gene="hk06"
                     /locus_tag="VVO74_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU5695617.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIYE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(4333..4986)
                     /gene="rr06"
                     /locus_tag="VVO74_001620"
     CDS             complement(4333..4986)
                     /gene="rr06"
                     /locus_tag="VVO74_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU5695618.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDEITQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            complement(5307..7739)
                     /locus_tag="VVO74_001621"
     CDS             complement(5307..7739)
                     /locus_tag="VVO74_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU5695619.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(7741..8199)
                     /locus_tag="VVO74_001622"
     CDS             complement(7741..8199)
                     /locus_tag="VVO74_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU5695620.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRDLLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            complement(8322..9047)
                     /locus_tag="VVO74_001623"
     CDS             complement(8322..9047)
                     /locus_tag="VVO74_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695621.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLE"
     gene            complement(9047..10054)
                     /locus_tag="VVO74_001624"
     CDS             complement(9047..10054)
                     /locus_tag="VVO74_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU5695622.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(10093..10851)
                     /locus_tag="VVO74_001625"
     CDS             complement(10093..10851)
                     /locus_tag="VVO74_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5695623.1"
                     /translation="MRNLRSILRRHISLLGFLGVLLIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            complement(10814..11104)
                     /locus_tag="VVO74_001626"
     CDS             complement(10814..11104)
                     /locus_tag="VVO74_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU5695624.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     regulatory      complement(11175..11277)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(11360..12706)
                     /gene="cbpD"
                     /locus_tag="VVO74_001627"
     CDS             complement(11360..12706)
                     /gene="cbpD"
                     /locus_tag="VVO74_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU5695625.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKTEPLASGTVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     gene            complement(12795..13061)
                     /locus_tag="VVO74_001628"
     CDS             complement(12795..13061)
                     /locus_tag="VVO74_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695626.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            complement(13063..14415)
                     /gene="dnaB"
                     /locus_tag="VVO74_001629"
     CDS             complement(13063..14415)
                     /gene="dnaB"
                     /locus_tag="VVO74_001629"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU5695627.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            complement(14458..14910)
                     /gene="rplI"
                     /locus_tag="VVO74_001630"
     CDS             complement(14458..14910)
                     /gene="rplI"
                     /locus_tag="VVO74_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU5695628.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            complement(14907..16880)
                     /locus_tag="VVO74_001631"
     CDS             complement(14907..16880)
                     /locus_tag="VVO74_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU5695629.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQIIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            complement(17016..17564)
                     /gene="raiA"
                     /locus_tag="VVO74_001632"
     CDS             complement(17016..17564)
                     /gene="raiA"
                     /locus_tag="VVO74_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU5695630.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            complement(17644..18306)
                     /locus_tag="VVO74_001633"
     CDS             complement(17644..18306)
                     /locus_tag="VVO74_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU5695631.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            complement(18303..19601)
                     /locus_tag="VVO74_001634"
     CDS             complement(18303..19601)
                     /locus_tag="VVO74_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU5695632.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            19657..20292
                     /locus_tag="VVO74_001635"
     CDS             19657..20292
                     /locus_tag="VVO74_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU5695633.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            20577..21497
                     /gene="cysK"
                     /locus_tag="VVO74_001636"
     CDS             20577..21497
                     /gene="cysK"
                     /locus_tag="VVO74_001636"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU5695634.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLVLAPDNGERYLSTALYEL"
     gene            complement(21694..22092)
                     /locus_tag="VVO74_001637"
     CDS             complement(21694..22092)
                     /locus_tag="VVO74_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5695635.1"
                     /translation="MKAPIPKAPLAHSFGSASIIAHTIHQKFNLKVPNYRQEEDWAKM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
BASE COUNT         6392 a         5000 c         3732 g         6988 t
ORIGIN      
        1 gccatagcac cattagcgtt gagatagtac catgagccat tgtattctag ccagcctgtt
       61 gccattgaac catcagtatt gtagaagtac cacataccgt tttcttgttt ccagcctgtt
      121 tttggagctt ctggagctgg agccggagtt tctggagctg gtgcttccgg aatttgcggt
      181 gtgtctggag cctttggtgc ttctggaacc tgcggtgtgt ccggagcctt tggtgtatct
      241 ggaacctttg gtacctctgg gctctttggt gcttctggaa cttgcggtgt gtccggagcc
      301 tttggtgtat ctggaacctt tggtacctct gggctctttg gtgcttccgg aacttgcggt
      361 gtgtctggag cctttggtgt atctggaacc tttggtacct ctgggctctt tggtgcttcc
      421 ggaacttgcg gtgtgtctgg agcctttggt gcttctggaa cctttggtac ctctgggctc
      481 tttggtgctt ctggaacctg cggtgtgtcc ggagcctttg gtgtatctga aacctttggt
      541 acctctgggc tctttggtgc ttctggaacc tgcggtgtgt tctgaattaa gcctttttgg
      601 aatttagtaa caaccgtatc catgtctgca aataccttgt ggactgtatt ctcaatttct
      661 actttggtat ttacattatc aatttcagaa agtgcttgct ttttaagttt atcaaggtcc
      721 ttaataagag caacaatctg atgatgtttt tctttcttca gatgatgttt ctttatatca
      781 tctaaaatct tgctcatgta tgttgctata gcaagtttag ctttttcttt ctcctgatta
      841 atatctggta cgcttggttt ctcaccctct ggttgtggtt ttggctctgg gttttccggc
      901 tgtggtttaa cctctggtac caatttcgct ttagcttctt tcaatttaga catggcatcg
      961 ttcaatttgg ttaattgcat tgccaattca tccattgtca ctgctgtctg tgatagaagc
     1021 ttcttgcttt tgtcaacaac ttctttcgca taagttctag tctcattata ggcttttcca
     1081 gcttctcctg tgagtttagc cccatctgga acagtctttg tttcatcgtc tagtttgttc
     1141 aaggcttctt ggaattgacg aatcaagtct tgtaactttt tcttttcagc ttcggtcgcc
     1201 ttttgtcctg gactttggga agttgatgga ggtgtttgcg tcaccggtgg tacaaccatt
     1261 gaaccacctg cttgtcctcc tggttggggt gctggttggt tttctttttc tctattttgg
     1321 tgagtcacga taagagactc tatttttcct tctgcttcct ttcgcaagtc ttctaccgat
     1381 tttttatctg aagcatcctc taattttgtc ttgtattctt ccacaacctt cttagccatc
     1441 cataagaaga tctgcaaacc aaaaaacaga tggatccagc ttcgttaaac gagttaccat
     1501 ataggtagac agagtttctt tcgctttgtc tatcgtttcc ttaagttctc tcgaatcgcc
     1561 tacttgcgga gaatttcttc gcactctaga ttttggcgtt tctttggttg agttatctaa
     1621 tttatacaaa tacgtttttt caatatctga tttaattttt tctagttttt taacattact
     1681 tttagcagct tctactttag atttagcagc attaattttc tcagtatctt gaggtatttg
     1741 aacttgagct tgtgcaaact caagctcaag ctctgccttg gcgaccccta cttctgcttc
     1801 cgcaatttcc agttcgattg ttttgtaagt attggttggg tagttacggc gatcttcttc
     1861 tttttgagct ttggcttttt tctcagcttc tgctaccttt tttcctgatt tcaatgtatc
     1921 ttttttaaac tgctcaaaag ctgcggttaa ctcttctttt gtttcttttg tttttaacgt
     1981 caactcagct tccgacttct cttttaatcc atacaaatac ttcgttttaa ttctgctcaa
     2041 ctttttgttg aagtcgacat tttgggtatg ttgaactttt ttcaaatttt tattgacatc
     2101 cttcaatata ctttgtagat gcgactcgac ttcatcagca tacttcttcg atatatcttg
     2161 cccactagat gtaaccgtga ggttattctt actcctaacc ccttctgcat ggactactcc
     2221 tcctaagaac aagctggcaa ctactacact agctactcca atactaaatt tacgaattga
     2281 ataatgtact tttctttcgc tttttgatgc aaacatgttt atttccttct atattttttc
     2341 tttaacctta ctatatcact tcaatatgaa ctgtatatga gtcgaatttt gtatttatct
     2401 ctttatgctt ccatttggga ttataacttc atgtaatagc ttttcctctt cagctattcg
     2461 tcgatacaaa ataactgcat aaactggaaa aactaaaaca aaagtcatat aggcatgact
     2521 caacaaggtc aagccaatca actcaggtaa aatatttaaa aagtaattag ggtgttttac
     2581 tgtcctaaac aagatatgat ctacatattt gtgattattg acaagcataa gcttcactgt
     2641 ccaaatatct cccaacaagt gaatcaccaa catcaacatc agcatagaaa aaataagcaa
     2701 gactaaacca accatgccca tgccatcaaa aattgtcttg tgcaccattg cctcaaccaa
     2761 gcaagagaga taaaaaacaa tatgagccat agttaatcgt tttgtattct caactccaaa
     2821 ttctttcccg ccattgctaa ggattcgttt ctcattctct atcgaacgct ttaaaaaaat
     2881 caatcgaata aagaatgtta ctaaaataat cgctaatacc atattagtat cctttctttt
     2941 atctacacaa agaataacac acttatgtta accctatatg aactttaata aaaaactaat
     3001 ctgtctacaa gctaatctta aattccatac cgtgttcata agggagaaaa ctataatcca
     3061 tttgatagct ttctaaaata ttattcacaa tgtaaagacc caaaccggaa ctttcatcct
     3121 tatctgtcac gatttgagaa tgataaaata tatcaaataa atgttctagt tcttggtcac
     3181 ttagaggcgc acatgtattt ttgatagaga gatagccatc ttgctcggat atgattacgc
     3241 gcccattttt atctgaatat ttaattgcat tactaatcag gtttgtcaaa accttatcca
     3301 atgccctaag actcatgacg actctggtag catctgtcaa ttgattttca attgtaacac
     3361 ctattgaatg agctaattct tgataacgtg ataaaatatc tactaaaact ggcttaacag
     3421 tcaaagtctc acgacactct gtccactctt ggaatttaga agactccagt acttcttcca
     3481 ataagtggct catctggtca atcttattta tactctttgc aatatatttt ggatgatctt
     3541 tgtaatctcc aatattatgc tgcatattct ctaggataat tctaagactg gctaaagggg
     3601 ttttcaactc atgtgatgct ccgcggacaa aggaaacctt ttgattttgc aattttacaa
     3661 tttgctcatt acgactttcc aactcataaa taaccttcaa caagtgctca tacataccat
     3721 taatctgttt tccaacttca ccaacttcat ctttcctact ttcatcaaaa cgaatattgt
     3781 catccaaatc ttgcatttta ctagtcactt ctgaaatgta aaaaagagga ttgagcaagc
     3841 gtttagtata aaaataagaa aaaacaaagg aaaaagcaat tgtaaccaaa aatgtatatg
     3901 ggagatacaa aagcaaaata ttctttgctt ctttgtagac atccaccccg tgaacaaatt
     3961 gcactgttac ctgtttacca tctgctgtac taacagacat atctaacatc acgatataat
     4021 ttgatagctt tccatcttta atatccaagt catgcacaag agggagccgc ttatctacaa
     4081 tatctctttt aaggtgagca gatatggtca aggactttga ataagactgg agtaagcttg
     4141 gaatttcatc agatgtctta gtctttaaat actccgtaaa cactcttgcg ctctcattaa
     4201 acttttcccc ctccagttga atataataaa aaggaaaggt caaataaata gctatatgaa
     4261 tgactagacc aacaccacct agaattgcaa aacttcttaa aaaggacttg gttaataatt
     4321 taggattttt tatcataaac taatcttata cccaacattt ttcacagtca cgatacaatc
     4381 taaagctaat tttttgcgaa gagtacgaat atagacatca acgaccctat cacaaggtaa
     4441 atcagctaca tcttttgaaa tttcttccaa tatctgctct ctacttaaaa cttgattttt
     4501 atgctgaatc aaacacttta gtaccagtaa ttcctttggt ttgagatcaa tttcttcatt
     4561 tttataatgt gctttgtaag aggtaaaatc cactgttaca tcctgatatc gccaaatatc
     4621 ctctatgacg tagtaacgtc tgataagcgc cttaatacgc ttgacaagca gtaccaaaga
     4681 aaaaggtttt gtcacatgat catcagcata gagatcaaat acctgtgact gagtaatttc
     4741 atctcccaga gcactcaaga cgatgacagg aatatcgtgc ttttgattga tttcttttaa
     4801 cacttcaaaa ccactcttcc taggcatcat taaatccagt accatgagat ggatagggag
     4861 atcttgaaat ttttccaaga cctcttgtcc atccttagcc ataatgacat gataaccctc
     4921 ttctgtcaga aatgctgcaa ttccttctct aatcatttcc tcgtcatctg caactaaaat
     4981 gttcatctct ctccctttct actaccagaa ctccatacat ctatttcctg tatgctattt
     5041 gaaaatttcc taccagccta tcatctatga taatagaatg gatttcattt atccgctact
     5101 ttttgtcaac aacaacgtca atacaagaaa atcattcatc ttgcagctta tactcttcga
     5161 aaatctcttc aaaccacgtc agctctatct gcaacctcaa aacagtgttt tgagcaacct
     5221 gcggctagct gcctagtttg ctctttgatt ttcattgagt ttcactccac tgtgacttat
     5281 ggtcagatgc tggtactttt attcttttat gcaatatcaa attttaactg gcctgctttg
     5341 acaccaatct taagtgtgct gcctgccact aaatctccct tgagaagaag ttctgccaac
     5401 ttgtcctcca cttctgtttg cagggttctg cgaagtgggc gagctcccat ctctgggtca
     5461 tatccttgat ttgctaacaa tttcagagct gaagcttgta atttcaagtc aatgcctttt
     5521 tcagccaaac ttgccactaa aggcttgacc ataatcttca ccacttcctg catatgatca
     5581 ctagataggc tatggaagac caccttctca tcaatacggt tgatgaattc cggtctataa
     5641 gcttttttca gttcttcaaa catgcgtttt tccatatttt cctggtcaaa acgaatatcc
     5701 ttagccccaa aaccaacagt cttatcatca cgaagggcag tcgcacctag gttcgatgtc
     5761 ataatgataa tggtatttga aaaatcgacc ttgcgtccct tgctatctgt caagacaccg
     5821 tcatccagaa cctgcaagag aacattaaag atatctgggt gagccttctc tacctcatca
     5881 aagaggagaa cggaataggg tttattgcga accttctctg tcaactcccc accttcttcg
     5941 taacccacat agcctggagg agctccattt agacggctgg ctgcgaattt ctccatatac
     6001 tcactcatat caaagcggat aagggctgat tcgtcatcaa agagaacttc tgccaaagcc
     6061 ttggccaact cggtcttacc gacacctgtg ggtcctagga acataaagga accgatcgga
     6121 cgcttgtgac tgcgaattcc tgactgatta cggcgaatcg cacgactaat acttgaaaca
     6181 gcttgatctt gaccgataac ccgtttatgg agttctgctt caagatttag atatttctta
     6241 gcgtcagtct gagtcagctt ttgaactggg attcctgaca agcgactcaa ggtggtcaaa
     6301 atatcagact ctgtcaccaa gtctttgtag acaggtactt cctcttcttt tgcgattagc
     6361 tgggctgcct gtttccactt gccatccatc agggccttgt cagctggact caaatctgaa
     6421 tcgtctgctt ttacatgctt tgccttattt tgcactgttg ctgctgcttc gtccaagagg
     6481 tcgatagcag agtctggcaa gtgacgactg gttaaataac gatgagccat cttaaccgct
     6541 gtttcaaccg cttcatctgt gatttgtaca cggtgatgtt tctcataagt cgccttcaaa
     6601 ccttgtaaaa tagtcatact atctgccaca cttggttctt caatcgtcac tttagcgaaa
     6661 cgacgagaaa gtgccgcatc tttttcgata tgtttttgat attcttcctg agtagtggca
     6721 ccaaccgttc tcaaagttcc acgcgccaag gctggtttca agatattggc cgcatccaga
     6781 gtcgaatcaa tcccgctacc agaacccatg atggtgtgga gttcatcgat aaagaggatg
     6841 acttggccat cttcttcaat atccttgatg atattattca tgcgttcttc aaagtcacca
     6901 cggaagcgtg tccctgcaac gacattcatc aaatcaagtt ctaacacgcg catcttagcc
     6961 atttccgcag gcacgtcacc actagcaata cgctgggcaa gaccaagggc cagagctgtt
     7021 ttcccgacac cagcatcccc aaccaagaca gggttgttct tagtcttacg gctcaagatt
     7081 tgaatcatac gtgagatttc cttgtcccga ccgatgactg gttctaactt gccagaacgc
     7141 gcttgctctg tcaaatcatg cgtatagtcc tcgagaccac cactaggagt ctgcggcatg
     7201 cccatcatat tggccataga attttgcttg tcagctactg tacgatggcg ttggcgtaaa
     7261 gccttgagat cttcacgagt ccagcctgca cgttcttcta aatttcgacg aagggcagca
     7321 atcttgacct gatctttctt gtcttcataa gaaaaaccag ccctctccaa gatacgagtc
     7381 gccaaggcat tgccatcatg caaaatcgca tagaggacgt gctctgtccc tagtacctta
     7441 gcatggacca ctgacgctac atactctgct tcatcaaaaa gaacctgcaa acgacgggag
     7501 aacggcaatt ccgtaaaggt ttcatcctgg ctatagtccg tttcagtcag ttccaaagcc
     7561 acctcttcta aacggtccat ctcatacgga taatcattta aagttgcccc tgctacacta
     7621 taactgtgat tagacatggc aatcaacaag tgccacgact ctagataacg agctccaaaa
     7681 tgtccagcaa ccatgtaggc actttcgata cattcattca atgcttttga atagttcatc
     7741 ttacttccct tttctatcta cctcttgtat gacctgacgt agcatgtttg ctcgaacaac
     7801 tggagcttct tctcctaaaa cgcgatccaa agctactgat tctagcaaat tcatctcctg
     7861 cttggtcatc aattcctgct caaccaaaag ctggagaata tcctcataaa tttcttgact
     7921 gactcgctca ccaatcgagt aaagcagatc ccggagcatt tcatgatgac tagaaaactc
     7981 aatccgtcct atacgaatgt agcctccgcc accacgctta ctttcaacca agtagcctct
     8041 actttccgta aagcgtgtct tgatcacgta gttaatctga ctaggaacaa cctgaaaggt
     8101 atctgccaac tgactccgtt gcaactccac gataccagat tgatctaaaa tcgccttgat
     8161 gtaggcctca atatgatccg atgtattttt aaatctcata acaaacccac ctctctcttt
     8221 aaaccttgac cttgtttgac tattataccg aaattttctc atttttaaaa gaaaaagggc
     8281 gctggtaaag gataatcttc accaactccc tatttttcta cttattctaa gcctaattct
     8341 gccaagattt gacgtttgta ggcaatcttt tggacttcct tgtcctcatc ttcagaccaa
     8401 tctagtttaa tttctgaaac aatctgccca gggcgatttt tcaagatata gatgcggtcg
     8461 ctgagattga gggcctcctc aatactatgc gtgatgatca gagttgttag ctgcaactgt
     8521 ttgtgaatct caagatacca agcgtggagt tccatctttg tcatctcatc caaggcgcta
     8581 aaggcctcat ctaagagaaa gagcttgtgc ccaaaaaggt aggtccggag taaggctaca
     8641 cgctggcgca tcccaccgct aagttcatga ggatacttgt ctcttacagc tgtcagctgg
     8701 aaggtcgcaa gaattttatc cgctcgggaa atagcttctg ccttatccac cttttgaatc
     8761 aagaggggca gaatgatatt tccaagcacc gtcttgtgct ccaagagcag atccttttgc
     8821 aacatataac tcacgcgccc cttgggattt tcttcaccat caaggacaat tctccctgac
     8881 tgaacttcta aaatcccagc gattagatta aagagggtgg tctttccaac accacttggg
     8941 cctaggatgg aaaccacttc gcctgaagtc acctgtagat tgatatcctc taaaatcctc
     9001 tcctgaccat aggcataact gacgtgctct agtctaattt ctgtcattat ttcacaaatt
     9061 cgttggtgaa gcctttgtct gtcaagtctt ctttaaggat accattttct ttatcccatt
     9121 tgtagaaagc attccagcga gctgcgtcaa attgacccca tttttccttg tcgcttgcgt
     9181 attcttttga caagtatttt tgagattcga tgacaaagtc acgtttttcc ttgagttcag
     9241 gtgcattctt gatgagaata tctgcagctt cttctggatg ttccatggca tattggtagc
     9301 cttttttgat ggcttggatg actttgcgag cttcttcttt gttatctttc agatagtcgt
     9361 tgtttgcgat gataactggt gaatagtagt caaactcctt gacatagtct ttcaagtaca
     9421 tgaagttagc atctacacct tgagatttag caaggatacc atcccaaccg tagtaaatcc
     9481 aagcagtatc aaagacgcca ttggcaatcg gtgtgattga gtttgagtcg ttatttggta
     9541 ctttttcaac cttctcaaag tctccacctt gagattctac caaggttttc aacatagcaa
     9601 gttcagttgg gtcattccat gtcccatatt tcttaccaac caagtctttt ggactgctta
     9661 cattatcaga tttacgagag atgattcctg atgtattgtg ttcaacaata gctgcaacgg
     9721 cagtgattcc tgctcctttt tccaatttct tagccatgta gtcttggaaa tacactgcaa
     9781 atggtgcctt tccgttgata accaagtcag aagaactttc ttctggtggc aatttcaaat
     9841 caacatccac tccagcttct ttgaaataac ctttttcctt ggcaacataa agccctgtgt
     9901 ggttggtatt tggtgtccag tctaggataa agtcaacctt cttaagttct gcctctttgt
     9961 tgtctttaga agcagttcct tgaccacagg ccacaagcac aacagctaca agagctgtta
    10021 caagcgttaa aaacactttc catgttttct tcattttgat ttcctctttt ctttttcaga
    10081 aacattctaa ttctacgaac gtttccattt aatcacatat ttttcactga tatcgaccag
    10141 cttcataccc aaaagactga taatcgacac cagaataata atggcaaaca tggtatcata
    10201 ctgaaacaat tttttagact gaatcatata aacaccaaga ccttcaaaac ctcccaacca
    10261 ctcagatacc acagttgtga taaaggcgta ggagacactg accctcagac ctgcataaaa
    10321 gtaaggcagg ctaactggga ttttaaaatg ccacaggatt tgccaaggct tggcccgcat
    10381 cagactaaac aaggtcagca tatccttgtc gcaatgccta aaaccgtcca aaatactaac
    10441 gatgatggga aaggttgtcg ttaagataat caagacaatc ttgggcaaaa tcccataacc
    10501 tagccacaag accaggatag gagctatggc aatggtcgga atggtctgaa tgaccaccat
    10561 catagggtaa atcaggtcat tgagccaagt caaactatcc atgagcacag ccataagaca
    10621 ggcaatcaaa actcccaaaa tcagccccag taaagccact ctcaaggtcg cccagctatg
    10681 gtgccagaga aattctctgt cacgaacaaa gggctggaga atttcaagag gtgtcggcag
    10741 gataaacttg gggagaagtt taagaaaacc tgctaactgc cagattaaca agactccgag
    10801 aaagcccaat agactaatgt gtcgtctcag tatacttctc aagtttctca tcaatactta
    10861 aaatctctcc tacatttatt ttgacattgg caaagacatt gtctgcctcc tgccctgcca
    10921 cttccagcgc ttcttttaga atgcgcataa gctcatcaaa ctccccttcc aagaccgttt
    10981 caaatggtgt cactaccatc gtcacttctt gagtttgcag ataagcaatg acctgatcaa
    11041 taacagctat ccgatcaatc ccctgtgcta ggggtaaaac ttgcaaggca atgcttgctt
    11101 tcataagaac ctcctcttct cgttttcctt tttaaaaaaa gaaaaacctt taccatacat
    11161 ggaaaaggtg caaaattaga ctaagtatcg ttccctccgc tggcattacc cagatcaggt
    11221 gcggtcgaag tttaacactt cctctcagac tgtacacaga ctcccatata ttatatgtat
    11281 atatgatagc gcaaaataag aaaaatgtca aggaaactgc ttacagaaaa gagcaggaaa
    11341 tttctcctac tccaattttc tatactcgtt ctccatcact gtttactctg tagccatcca
    11401 ccgtcgtatt aacagctaag gcgcctgaag agtaagaata ataccactta ccagagacct
    11461 ggtaccagcc tgttttcatt gcccctgaac tacccagata ataccacgag ccattctcct
    11521 ttaaccatcc tgtctgcatt tcaccagata atttcaaata ataccagcta gaaccgtctt
    11581 tcagccatcc tgttgattta gaaccatttg atttgaaatg ataccaacta ccatttattt
    11641 tcttccaacc gacagttgaa ctattattgg atccatagct agagatattt cctgattgat
    11701 tctgataatt ttgtgaagaa gtcactccct ctagctgtat atagcgacga cttccattat
    11761 aggcagtata actcaaccac ttgtagccgt ctttttcaag tatctgatca taatgaacct
    11821 tctctccagg ataatagtaa tcaatcacag ttccgctaac taggggttca gttttgatag
    11881 cagacttggt cttaaaataa tgagttccac ctgttgaaga aagaacagaa ttacctagag
    11941 gatttttatt cacagcctcc aattgaacat aacgatagct tccattatag gcagtataac
    12001 tcaaccactt atagccgtct ttttcaagta tctgatcata atgaaccttc tccccaggat
    12061 aatagtaatc aatcacagtt ccgctagcta ggggttcagt tttaatagca gacttggtct
    12121 taaaataatg agttccgcct gttgaagctg aggattgact attcccaaca ctgccgccat
    12181 ccaaatcttt aaaatgaata aatcctgtca tcgtgtttgc ttttataact cgtttattat
    12241 aggattctgt ataaccatag ttatattcct caatctcaat ctgatctccc attacatttg
    12301 acacccaggc aacatgacca taagttcctg cagtagacca agtaatggaa ccaatcgtcg
    12361 gtgtattatc tacacgataa ccttcccgac gagcacgatg tccccattca ttcgcatttc
    12421 cataagctgc cggaatttca aaaccattga cattactcaa acgaaaggct acaaaagaag
    12481 tacactgacg agaatacatg cgccactgat caatctcctg gctcccattt ttataataag
    12541 caggataatc atccccgcgc gcaatcgatc catttcctcc ggaataggca tagacactat
    12601 caccagctgc tagcatcaat cctactacta aaaaaggaac aagcttttta actgacatct
    12661 tcaagtaata acttgtccct cttgctataa acggtaaaat tttcattctt cctccttgaa
    12721 aaataatata aagcgatgat tgccttcacc taaattattc ggagaaaaaa gaaaaagtga
    12781 gaaaatttct cactttagtc aagataatga atcaaattct tttctgtaag aatatctgag
    12841 taagtaaagg attcaacgta aacattaact tgtttatctc cttccacatc cccaaactcc
    12901 acaataaata gagatggata aacttcaatt agcttaccca atctattttt ttggcgctta
    12961 cgaccattct ccaaagtcat ttctacgact tgtccctcat gtgccttgat ttcttctttg
    13021 atttttttca tcttggctac atctgtaaat gcatctgaca tcttatgcct ccctctttga
    13081 gatacttgaa aatttattgt attctttttg gaaaatcaat tccactgttc cacgagctcc
    13141 actacggttt ttctcgataa taacttccac cttattattt gggataccct cctcttcttc
    13201 accaccacgt tcatagtagt catcgcgata gagaaaagct acgatatcag cgtcctgctc
    13261 aatagaccca gattcacgaa tatcagacaa gaccggtctc ttgtcctgac gttgttctac
    13321 accacgagaa agctgactca gagcgattac tggaaccttc aattccttgg ctagtatttt
    13381 caactgacga gaaatttcag aaacttcttg ttgacgattt tctcgaccag ttcccgtgat
    13441 aagttgcaaa tagtctatca aaatcaaacc aagatttcca gtttcttgag ccaatttacg
    13501 agaacgagaa cgaatctctg taatccgaat acctggcgta tcatcgatat agatactggc
    13561 gttagctaga ttaccctgag caatagtata tttttgccac tcctcatctg tcaattgccc
    13621 tgtacggata gaatgtgact ccactaagcc ttctgcagct aacatacgat ctaccaagct
    13681 ttccgcaccc atttcgagtg aaaaaatagc aaccgttttg tccaacttag tcccaatatt
    13741 ctgagcgata ttcaaggcaa atgctgtctt accaactgct ggacgagctg ctaagataat
    13801 caactcctcc tcatgaagtc ctgttgtcat atgatccaaa tcacgataac ctgtcgcaat
    13861 acctgtaata tcggtcgttt gttgcgagcg agcttccaga tttccaaagt tgagattcaa
    13921 cacatctcga atgttcttaa acccgcttcg atttgcattt tcactgacat caatcaaccc
    13981 tttttctgcc tgagcaataa tttcatcagc tggttgtgac gcttcgtaag cttggttgac
    14041 agactctgtc aacttggcaa ttaaacgacg tagcattgct ttttctgcaa caatcttagc
    14101 ataatactcc gcattagcag aagttggcac agaattaaca atctcaacca agtaagacaa
    14161 gccaccaata ttctgtaaat caccttgatt atcaaggata gtacgaaccg ttgttgcatc
    14221 tatggcatca ccacgatcgg ataaatcgac catggcttgg aaaatcaaac gatgggcata
    14281 cttaaaaaag tcccgagact caatgtattc tcgcacaaaa acaagtttac tctcatcaat
    14341 aaagatagcc cctaaaacgg attgctcagc taagatatct tgaggttgta ctcgtaactc
    14401 ttctacttct gccatcagac ttcccttctt ttacaatctt gtcaagaaag tgtaaactta
    14461 tccttctttc acacgaagat tgattacact tgtgatatct tgatagattt tcactggcac
    14521 atcaatcaaa ccaaccgctc gaatcggagc ttgtacttga atatgacgtt tatcaatctt
    14581 aattccaaat tgcttttgca attcttctgc aatcttctta ttggtaatag aaccaaaggt
    14641 acgaccatct ggaccaactt tttcaacaaa ttctacaaca gtttcttctg cttcaagttg
    14701 tgctttaatt gcttttcctt ctgcaatcat ctcagcgtga gctttttctt ccgatttttg
    14761 tttaccacga agttcaccta cagcttgagc agtcgcttct ttggctagat tctttttgat
    14821 aagaaagttt tgcgcatacc ctgttggtac ttccttaatt tcgccttttt taccttttcc
    14881 tttaacatct gctaaaaaga ttactttcat tcttctttct ccttttcctt tatttcattt
    14941 aatacaattt ctgtcagttt ttcacctgct tctgacaagg ttacatcttt aatttgagct
    15001 gctgccaaat taaagtggcc tccaccgcct aactcttcca taatccgttg tacattcagt
    15061 ttactacgac ttcgagctga gatagagata aatccttgtg tattcttcgc aagaacaaaa
    15121 ctcgcttcaa tacctgacat ggctaacatg gcatctgctg ccttactaat aacaactgta
    15181 tcatagcatt tcgtgtcctt agcctctgct attagtacat ctgaacctaa tttacacccc
    15241 tgtaaaataa gttcattgac ctcacgatat tcttcaaaat ctgtcgcagc gatttcctgg
    15301 atagcaatac tatcacttcc gcgcgttctg agatagctag caacatcaaa tgtccgacta
    15361 gttactcgcg aggtgaaatt tttagtatcc aacatcatac cagccatcaa aacacttgct
    15421 tgcatacgac tcaaacgatt tttcttagaa ttctggaact gaatcaattc cgttaccaac
    15481 tcactggcac tacttgcacc actttcgata taagtaataa ccgcattatc tggaaaatcc
    15541 tgatcccttc tatggtggtc aataacaatg atttgggtaa ataaatcata aaattctttt
    15601 gataatgtta aggctgtctt tgaatggtct acaagaatca acaaagaacg attggtcacc
    15661 atccccattg catccttaac agacaacaac ttcgtaactc cttctttttc tatgaatgaa
    15721 acagctcgtt caatatctgg agacatttgt tcttcatcat aaagagcata gctattttca
    15781 atcacattgc tggcgaacaa ctgcatacct acagcagagc ccaaagcatc catgtctaaa
    15841 tttttgtgac cgactacaaa aacctgatct acactccgaa tcttatctga aatagctgtc
    15901 atcatagcgc gcgtacgagt ccgtgtacgc ttgattgaag cagcagaccc accaccaaaa
    15961 taaactggat ttttcgtttc gtcgttttcc ttaacaacca cctggtcgcc accacgtact
    16021 tcagccaagt tcaaattgag caaagcaact ttccctatct catcatgatt tccatcgcca
    16081 taagaaaatc ccatacttaa ggtcaagggc aactgtctct gtttcgactc ttctctgaaa
    16141 gcatcaataa cagaaaattt atcattcatc aagccctcaa gcaccgtgta gtcagtaaat
    16201 agataaaatc gatccatact tacccgacga gaaaacatca tgtatttttc tgaaaactct
    16261 gatataaaat tagctacaaa actattgatt tgactaatat ctgactcaga agttgcatcc
    16321 tccaaatcat cataattatc cacagagaca atcccaatca ctggtcgact tgttaccaat
    16381 tcatctgtta tggcttgttc cctggataca tctacaaaat acaaaacacc ggaagaagca
    16441 tccatatgaa cagcataacg cttctcacca agcttggcat aagtagacgg atttcctact
    16501 gaagccttga taatcgtttg aacagcttct aaatcaaaat caccatcttc cttggtcaaa
    16561 atcaattcag catagggatt aaaccactca acctctccag aagataaatt caatttcata
    16621 acacctacag gcatctgttc caatagagct gtcaaacttt cttccgcttg gtggtttaca
    16681 tactgtatct gttctacatc actccttgta taatgcactc tcagtttctt aaataaaaaa
    16741 acatagcctc ctacaaaaag aaacaaaatt aaaaccgtca acagattatt attaacaaaa
    16801 ataatgaaag tggataagac tccaaacgca atcaatccta ctagaatagg aaaaattgga
    16861 cttacataaa attttttcat tcaaaacctc ttggcaccca ttataccata atacccctca
    16921 aaaagcgact ttttaaaagt gtaatcagta attctatcaa ttataagaaa aaggtagttt
    16981 acaattcagt aaacctacct ttacacatat tgaaattaag attctttaac ctctaacaaa
    17041 ccaatttcgc catcctcacg acgataaatc acattggttg tctgatcttc aacatccaca
    17101 tagataaaga aatcatgccc caataaatcc atttgtagaa ttgcttcttc caaatccatt
    17161 ggttttaaat caatttgttt tgaacgaaca actttagact ggacaatatt tgaatcttcc
    17221 accaaagcat ctgtaaataa ttgaccagtt gctaccttat ttttattttt acgctcgatt
    17281 tttgttttat ttttacgaat ctgacgttca attttatcag ttacaaggtc aattgaacca
    17341 tacatatctt gagatacatc ttctgcgcgg agagtaatag atccaagcgg aatcgttact
    17401 tccactttag ccgttttttc acgataaact tttaagttaa ttcgggcatc caactcttgt
    17461 tctggttgga agtacttttc gatcttttcg agtttagaaa ctacataatc acgaattgct
    17521 tctgttactt ctaggttttc accacggata ctatatttaa tcatatgagt accttctttc
    17581 taaacatttt tgtttttatg attttattat aacgctttca ttctattttt gcaaattttt
    17641 tcctcatctt acaagggaaa atgtttttac atccttagca ccagcttctt ccaacagttt
    17701 cttaacacga tttatagttg ctcctgtagt atagatatca tctataagta ggattttttt
    17761 aggaatagtg actccacttt taataaagaa aggaagttct gtccccaagc gctctgaacg
    17821 atttttagaa gaactggctc tctcttctct tttctctaat aaatccagat actcaaagcc
    17881 tgctgcctct accaagccct caacctgatt aaatcctctg ttagcatatc tatcaggact
    17941 taggggaatt acaacaaatt gatactcttt gtactttttc aactcctcac ttaaaaatga
    18001 agcgaaaact tttcttaaca ggaagtctcc atcaaactta taccgactga aaaaatcctt
    18061 catagcttga ttgtaagtaa aaatcgctct atgactgact tcaactcctt ctttacacca
    18121 aagttgacag tcttgacact ttgttgacaa ctctgttttc atacaatttg gacagttctc
    18181 ttccccaatt ctttcaaaag tagaatcaca gtctgaacaa agacaagagt catcattcct
    18241 cagaagtaag agactactaa aagttaaaac agtcttcata gtctgcccac ataacaagca
    18301 cttcatagac cagcctcctt attcatcatc tgaatttcct taatcgcctt cttgattgaa
    18361 gcatttaacc catcatggaa gaaaagcaaa tctcctgtcg gtctatccat gcttcgtcca
    18421 actcgtccac caatctgaat caaactagac ttggtaaaca aacgatgatt ggcctctact
    18481 acgaaaacat ccacacaagg gaaggtaact ccacgctcca agattgtcgt actgataagt
    18541 attgtcagtt ctccatctcg aaaagcttgt acttgctcta atcgatcctc tgttacagaa
    18601 gatacaaagc caattttctc atttggaaat tgctcctgta agatttcttc taactgctcc
    18661 cctttcttaa tttctgaagc aaaaatgagt aacggataag ctgtctttct ctgcttctca
    18721 atataggact ttaactttgg tgacaaacga ttcttgtcta agtagcgatt aaaatccgat
    18781 aaccaaattg gttttggaat aatcaacgga tttccatgaa accgtctcgg taaactcagt
    18841 ctttttagtt ctcctaaacg gaccttttta tctaactcat tggtcgaagt cgctgttaaa
    18901 aagattctca atccattctc ctttacacta ttcttgacag cgtggtaaag cgtgggatta
    18961 tcaacataag gaaaagcatc tacttcatcc actatcagca aatcaaaagc ttgataaaac
    19021 ttcaataact gatgggttgt tgcaacaact agtggtgttc gaaaataagg ttccgattct
    19081 ccatgtagca aagctatccc gcaagaaaaa tcctgttgca ggcgcttgta cagctccaaa
    19141 caaacatcta tgcgaggact agccaaacac actgcaccac ccgcattgat cactttagcc
    19201 actacttgat aaatcatttc tgtctttcca gctcctgtta ccgcatgaac taaggttggc
    19261 ttttgcttgt ctactgcttg aagcagtccc tctgacacct tctcttgaaa aggagttaat
    19321 tggccgcgcc atttgagaac atcttgcttc ggaaaatcct cctgcggaaa atagtataaa
    19381 gtttgatcac ttctgactcg cttcatcagc aagcactctc gacaatagta agcaccgatg
    19441 ggcaaatacc attcttctag aatagtacta ttacaacgtt gacagaaaag tttccccttc
    19501 tcctttctca ttgctggaag tttctccgcc aactgacgtt cttcttctgt taattcattc
    19561 tcagtaaata aacgaccgag ataatctaaa tttactttca tacttcttta ttcgtaaaaa
    19621 ctagcacttt agattatttt ttagtacaat taaatcatgg aatttaggac aattaaagag
    19681 gacggccaag tccaagaaga aatcaaaaaa tctcgcttta tctgccatgc caagcgtgtt
    19741 tatagcgaag aagaggctcg tgacttcatt actgccatca aaaaagaaca ctacaaagcg
    19801 acacataact gctctgcctt tattattgga gaacgtagtg aaattaaacg tacaagtgat
    19861 gatggtgagc ctagtggtac tgctggtgtt cccatgcttg gggtactaga aaatcacaat
    19921 ctcaccaatg tctgtgtggt cgtgacacgc tactttggtg gtattaaact aggcgctgga
    19981 ggactaattc gtgcttacgc cggcagtgtc gccttagctg tcaaagaaat tggtattatt
    20041 gaaataaaag aacaggctgg cattgctatt caaatgtctt atgctcagta ccaagagtac
    20101 agtaacttcc ttaaagaaca tgatctcatg gagctggata caaactttac agatcaagtc
    20161 gatacgatga tttatgttga taaagaagaa aaagaaacta ttaaagctgc acttgtggag
    20221 ttttttaatg gaaaagtcac tttaactgac caaggtttac gagaggttga agttcctgta
    20281 aacttagtgt aaacaatgaa taatacagcg tttcgttgac attctcacaa ctactttagc
    20341 gagcaaaata aaaagatgcg taccaaaata tactagaaaa tgaagcaatt caaacgaaac
    20401 ctgatatcgt tttccttcac acctatttac tagaattaac tgaacgcaat cacttgaaaa
    20461 ttaatgactt tgatctatga tatatagaaa tcctatcgct tcgataggat ttctatattt
    20521 tacaaatggt atggatagcg ttatactaaa gatatcttat acaaagaggt attcatatgt
    20581 ctatttataa caacattact gaattaatcg gtcaaacacc gattgttaaa cttaacaaca
    20641 tcgtgccaga aggtgctgca gacgtctata taaagcttga agcatttaat cctggttcat
    20701 ctgtaaaaga ccgtattgcc cttagcatga ttgaaaaagc tgaacaagat ggtattctga
    20761 aacctggttc tactattgtt gaagcaacaa gtggaaacac tggtattgga ctttcatggg
    20821 taggtgctgc taaagggtat aaagtcgtca tcgttatgcc tgaaactatg agtgtagaac
    20881 gacgtaaaat tatccaagct tatggtgctg aactcgtcct aactcctggt agcgagggaa
    20941 tgaaaggtgc tattgctaag gctcaagaaa tcgctgctga acgtgatggt ttccttcctc
    21001 ttcaatttga caatccagct aatccagaag tacacgaaag aacaacagga gctgagatac
    21061 tagctgcttt cggtaaagat ggattagatg cctttgttgc tggagtaggt accggtggaa
    21121 cgatttctgg tgtttctcat gcactcaaat cagaaaattc taacattcaa gtttttgcag
    21181 tagaagcaga tgaatctgct attctatctg gtgaaaaacc tggtcctcac aaaattcaag
    21241 gtatctcagc tggatttatt cctgatacac ttgatactaa agcctatgat ggtatcgttc
    21301 gtgtaacatc agatgacgct cttgcactcg gacgtgaaat tggtggaaaa gaaggcttcc
    21361 ttgtagggat ttcctcagct gcagctatct acggagccat cgaggttgcc aaaaaattag
    21421 gtacaggtaa aaaagtcctt gtcctagcac cagataacgg tgaacgttat ctctctacag
    21481 cactttatga attgtaaccg tccaataacg aagtatattg aaaaatctcc agactagaga
    21541 actcacggat agttcctaat ctggagattt cttatttgca cttttcttgt acaactttag
    21601 tccatggtaa ataagcctct aaaacctctt tgtttacgag agtttccacg tttggaagac
    21661 attctagaag ataggataga tatttctcac tatttataat ggattgaaat aagatatgaa
    21721 caaatcgatt aggacatgat ggtaaagcgt aatcccttgt ttctcagctt tcccagacaa
    21781 aaaagtccaa tagtaagtca gctgactatc actctctagc accctataag aagtttcatc
    21841 cgcatgaagt aagggctgag tcaatagtct ctctcgcaag aggttataga ggggctccaa
    21901 atagtattga ctcgtcttga tatgccaatt agagatttcc ttgcgtgtga ttggtaaacc
    21961 catcttagcc caatcttctt cttggcgata attgggtacc ttcagattaa acttctgatg
    22021 gatggtgtga gcgataatag aagctgagcc aaagctatgc gctaaagggg ctttaggaat
    22081 aggagctttc acaagcttat ccagatgatt at
//
LOCUS       DAVHKZ010000034        21676 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000034 DAVHKZ010000000
VERSION     DAVHKZ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.034"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..743)
                     /locus_tag="VVO74_001638"
     CDS             complement(<1..743)
                     /locus_tag="VVO74_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEU5695636.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMT"
     gene            complement(758..1606)
                     /locus_tag="VVO74_001639"
     CDS             complement(758..1606)
                     /locus_tag="VVO74_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEU5695637.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(1603..3078)
                     /locus_tag="VVO74_001640"
     CDS             complement(1603..3078)
                     /locus_tag="VVO74_001640"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEU5695638.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(3401..4756)
                     /locus_tag="VVO74_001641"
     CDS             complement(3401..4756)
                     /locus_tag="VVO74_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU5695639.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMAYKTEL
                     S"
     gene            complement(4766..5083)
                     /locus_tag="VVO74_001642"
     CDS             complement(4766..5083)
                     /locus_tag="VVO74_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU5695640.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEKTSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(5100..5417)
                     /locus_tag="VVO74_001643"
     CDS             complement(5100..5417)
                     /locus_tag="VVO74_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU5695641.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(5432..6328)
                     /locus_tag="VVO74_001644"
     CDS             complement(5432..6328)
                     /locus_tag="VVO74_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEU5695642.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNQEIIKAVQSAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(6331..7593)
                     /locus_tag="VVO74_001645"
     CDS             complement(6331..7593)
                     /locus_tag="VVO74_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU5695643.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            7873..9051
                     /locus_tag="VVO74_001646"
     CDS             7873..9051
                     /locus_tag="VVO74_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU5695644.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(9279..9725)
                     /locus_tag="VVO74_001647"
     CDS             complement(9279..9725)
                     /locus_tag="VVO74_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5695645.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            9795..10454
                     /locus_tag="VVO74_001648"
     CDS             9795..10454
                     /locus_tag="VVO74_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU5695646.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(10506..11657)
                     /locus_tag="VVO74_001649"
     CDS             complement(10506..11657)
                     /locus_tag="VVO74_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU5695647.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRASNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSICLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(11672..12403)
                     /locus_tag="VVO74_001650"
     CDS             complement(11672..12403)
                     /locus_tag="VVO74_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695648.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            12632..12733
                     /locus_tag="VVO74_001651"
                     /pseudo
     CDS             12632..12733
                     /locus_tag="VVO74_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(12705..13481)
                     /locus_tag="VVO74_001652"
     CDS             complement(12705..13481)
                     /locus_tag="VVO74_001652"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU5695649.1"
                     /translation="MPKTLTEKLNAIKVTGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIAGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(13474..14697)
                     /gene="trpB"
                     /locus_tag="VVO74_001653"
     CDS             complement(13474..14697)
                     /gene="trpB"
                     /locus_tag="VVO74_001653"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU5695650.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(14675..15274)
                     /locus_tag="VVO74_001654"
     CDS             complement(14675..15274)
                     /locus_tag="VVO74_001654"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU5695651.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVSLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(15261..16028)
                     /gene="trpC"
                     /locus_tag="VVO74_001655"
     CDS             complement(15261..16028)
                     /gene="trpC"
                     /locus_tag="VVO74_001655"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU5695652.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALAEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVVQRIKELQIDKG"
     gene            complement(16025..17029)
                     /gene="trpD"
                     /locus_tag="VVO74_001656"
     CDS             complement(16025..17029)
                     /gene="trpD"
                     /locus_tag="VVO74_001656"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU5695653.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(17040..17606)
                     /locus_tag="VVO74_001657"
     CDS             complement(17040..17606)
                     /locus_tag="VVO74_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU5695654.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEEGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(17603..18964)
                     /gene="trpE"
                     /locus_tag="VVO74_001658"
     CDS             complement(17603..18964)
                     /gene="trpE"
                     /locus_tag="VVO74_001658"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU5695655.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEEMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYLYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKTKSMTRIGE
                     LRP"
     gene            complement(19336..19479)
                     /locus_tag="VVO74_001659"
     CDS             complement(19336..19479)
                     /locus_tag="VVO74_001659"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695656.1"
                     /translation="MDRTDEVSSKYCFEVVDRTDEVSNHTYGKATLTRFEELFEEYKD
                     VPR"
     gene            complement(19468..19548)
                     /locus_tag="VVO74_001660"
                     /pseudo
     CDS             complement(19468..19548)
                     /locus_tag="VVO74_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(20150..21151)
                     /locus_tag="VVO74_001661"
     CDS             complement(20150..21151)
                     /locus_tag="VVO74_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU5695657.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(21259..21522)
                     /locus_tag="VVO74_001662"
     CDS             complement(21259..21522)
                     /locus_tag="VVO74_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695658.1"
                     /translation="MVFAFHLPLDELITNVIFKEKINSMLKCYIDRLLYVFINPTHFT
                     EKVNLQFYGSFFSYEFICREVGNILKNKGVKCNLNFFEGKEYL"
BASE COUNT         6753 a         4775 c         3442 g         6706 t
ORIGIN      
        1 gtcattccca tgacaaagaa taacatccct ttaaaacagt atcttaccca attttcaggt
       61 aagacttttg atacaaccgt ccccaatacc cctccgcata tagaagcaag aaaaataact
      121 ggaacaggtg ctaaatgata ctgatttaaa cctgtaacca caacaattgt agccaaatga
      181 gacaactggg aaaagaaaat aattgcaaga gaatacatcg ttgcttcttt tatcgaaata
      241 gaaaaaaaca ccatcaataa agatacattg agcggaccac caccaatccc taaaaaacta
      301 gaaatcaagc ccaatagaag accacaaatc atatagaatc ctatcttatc aaattgataa
      361 gtttttttaa aatctgttaa aacaaatgat acaagtagca tcacaaatag taaaatcatt
      421 tgaacaatgg atactagccg tactgataat tgagataaca aaacttgaaa aataagatga
      481 cctagaaacc ctcctaaaac agaagaaaag gataccgtaa aaatcaatct ccattttatc
      541 tctttacttt gtgaaaatct tttggttgtt gaaataatcg ccattataaa aacagagaaa
      601 ctagaataaa aagcaatatc actgaccgaa tggtatccaa aactatccat aagtggctta
      661 attataattc caccacccat gcctgatata gaacccaatc cactagctat tataatgatt
      721 agaaaataaa taatctcaac cactttttaa gtccatccta ttctttcaaa catctaaaac
      781 ctagatggct actagtggaa gtagaaatac atccatttct agcagctact cggtatcgat
      841 tacaataaga acaatgacat aaaaaggaac ctcctctgat agcatactcc tcatcttgta
      901 tcccatattt tggcaactca tagtcatctt cattaaaact agctaataag gtatatctcg
      961 gattgcgaca ccattcccaa acattcccaa tcatttgata tagaccaaaa tcattaggta
     1021 aaaattcata gacaggagcc gttcctataa atccatctaa ggcagtattt tcataaggaa
     1081 atcttccttg ccaagtattg gcatgataat atccaccttc taaaagagta tctccccaag
     1141 gatattcaga ttgtcttcct cctctagcag catattccca ctgtgcttca gtcggtaaag
     1201 acattccgct ccaattacag aaagccaatg catcttctaa agcaacatga actactggat
     1261 ggtcttctaa acccactaga ttactattct caccgtaggg atgtttccag caagcgttcg
     1321 gaacttgtaa ccaccacgga gccccagcag gatgaggata tccctccctt tctgcctctg
     1381 gaacgaacaa tataaaaaca aaagaccact cttgtcgctc agctagtgtt ttatagcctg
     1441 tttctttcac aaattgagca aattcttgat tcgtaactgg agtatccgca atggaaaaat
     1501 cctttacact aacagcgact tgaggacctt caaaatcatc taaaaagccc tcttcagaat
     1561 ttgttcccat cataaatgtc ccacccttga tttttttcat tttcatgatt gactatcccc
     1621 cgttttcgtt agagttggcg ttattttaga aagttcaaca ggaactaact cttcatccac
     1681 aacaaaacct tcttctctat atctaagaaa gtctactaat tttttcttca tctgacgaac
     1741 aataggttgg tatttttcac ttggatacaa atcattcatt tcatgcggat cttttttcat
     1801 atcaaataac tgataatgat ttaaaacagg aaaccagata aatttccact ggtctgtcaa
     1861 gatatattga ctagaatctt ttcctaaagc atgttcacca tgaaattctg ttcgccaccc
     1921 ctcgtactgt ccaaataata aattcttaac actccgtcca tctagttcat ctgtagtagt
     1981 tcctcctgcc aaatccacga gtgaaggaaa aatatcttga attttcacta attgcttgat
     2041 tgttccccta ttaccagcta tcaatccagc cggatcgtaa ataaacgaag gaatgtggat
     2101 acttccctga taaggatatc cctttctaaa cagataatgt tcaccaagct gatctccatg
     2161 atccgaaaca aaccagataa tcgtatcttt atcatgacga aattctttta gggcagtcaa
     2221 aaagcgacta atttgatggt ctatatgagt aatcaatcca aaataagcag caaccattct
     2281 tctttgatca tcttccttta atttccctct taaagcataa atagacggaa tttgcttttc
     2341 taatacttcc caattcccga tatgcaaatc gagaaattga ggcaagcgtt ccatatacat
     2401 atcaaaatag tattttgggg gatttaatgg agcatgtggt ttttcaaaag acattttgag
     2461 aaaaaaagga accgttggat ctcttctttg taaaaatgaa atggactcac tcacaaccca
     2521 gtttgttgga tgtaacttct catctttatc ccaaggtcta gcttcccaag aattacaatc
     2581 cattccgtca tcaatcaaat caacatcata accaacttta ccctttaaaa aggctagata
     2641 gtcactagca taatcaaatt gacttccata agccttatca tactttctat caacatgtag
     2701 atacccatcg tgaagtaaga catgatcaaa cccaagtctc tgtctggaag gaaaaacatg
     2761 catcttacca atacactctg tttgataacc catatcttta aagacttttg gaagagtatt
     2821 agtaaaattc caaggcacct catcttgata accaactcgt ccacttttat cttggtctaa
     2881 gccagtcaat aaagctgccc tagcaggaac gcaagaagga actggagaat aggcattttc
     2941 aaaattataa cctacactag ccatcatatc taatgttgga gtgctaacta gcttatcctt
     3001 actattcaag gataaggcgt ctgctctcat ttgatctaca acaatcaaaa taatatttgg
     3061 ctgttttgtc tgaaccataa aatctccttt ctaatatggc aaaagaggca caagaagata
     3121 tctaccttta ctgcacccct ttctatatca atctctctat ataaaacaat aacattcttg
     3181 ttatgtttta tagaaaaatg aactaaaata tgactaaatc gattaggaaa ttcaaatcat
     3241 tttctagtac tgttttagaa gttacagtgt actattccaa cttcaataaa ctataaacct
     3301 ttgtctaata acaattttag tggagataag aaatcctaca cctaactcat cttacacgta
     3361 atctatttct attttatcac aaaaaacgca agtaagacca ttaactcaat tcagttttat
     3421 atgccatttt cacaaatggg aaataagtca agacactaat aatcaaacaa acaactgata
     3481 agatgatggc acgccaatca aatgctgtag agaagaaacc atataaaatt ggaggcatta
     3541 cccaagtaac gttttgtgta acaggtgaaa caagacccca gcttgttgcc cagtaagcta
     3601 ccgttgccat gaaaaccgga ctaagtacaa atggtataaa tagcaaagga ttcaagacaa
     3661 ctggtaaacc ataattgacc ggctcaccaa tattaaacag aactggtgct agaccaagtt
     3721 tagcaacttt tcgataatga ctgtttcttg aaaaaattaa aatagcaagt actaatccta
     3781 atcctccaaa ccagacaaac gccccaaaag acccacttgt ccatatataa ggaatcggtt
     3841 cacctttttg gaaagcatcc agattcgcta acatagcaac tccaaacagc ccttccatga
     3901 tgggagccaa tacatttcct ccatggagac caaaaaacca gaataactta ttcaaaaaga
     3961 tcatcagaat aactgcaaag aaactttgag acaaacctag taatggcgtt tgtaacacct
     4021 tgtaaaccca atcaatcaat aagtcattgc taagtaaatg gaaaacataa gtcaagatgg
     4081 ctactatata catcgccata aatcctggaa tgatagaagt gaacggctta gcaatcgcag
     4141 ggggaactga atctggtaac ttgattaccc agttcttttt cattacttta cagaaaataa
     4201 tagaggctaa aaatccaatc atcatggctg taaagtagcc tctggcatta atatggtttc
     4261 ctggaatcac attcccaata gttaccatca gatttttacc atcaaatgct agattatcaa
     4321 ttccttgtaa gatttgatct aatttcacat ctcctacatt tgccaaaggg aaactctttg
     4381 taactgtact tccaatcgaa atgacaaacg aagcaagtga taccaaacca gcagaaactg
     4441 tatcaacctt gtaaatctta gcgatattca ctcccaagca atagatgaac aacaaggaaa
     4501 caattggtat acttcccttg aataccaaat tattgatgtc aacaagccac tgaaaggttt
     4561 tcgtaatact ttctaggtga aattgttgtg gtaaatccac tagaaaagca tttaataaca
     4621 aagcaatgga acctgtcata ataacaggca tagtccccac aaatgaatca cgtaaagcaa
     4681 ctaaaaactt ctgattccca actttcattg caattggaga aagtttttct tgcattttat
     4741 ccaacattgt attcatacca aactcctaat ttttttcaaa tcgttcgtat acttctacca
     4801 cttctttcgc caagtcaaca aaagtcagac tcgtcattaa atgatcttgc gcgtgtacca
     4861 tcaagaggct aattgatgtt ttttccccct gtgcctctct tgtcaacatt tctgtttgag
     4921 ccttatgcgc ctgtaataag gcagcattcg catcagctaa tcttcgattg gctttagaga
     4981 aatccccttt ttttgctgcc tgaatagcct ccatagcatt acttttggct tccccaccat
     5041 acataattag ccccattaca gattctaaat tactttcatc cataacattc tcctcaatct
     5101 tagtctaata aactttcagc taaatctaaa actttagaac cattcatcat tccgtaatct
     5161 gtcatcggaa taaccgccac aggaatctgt ctatctttta gtttttcttg aaagtcccct
     5221 agtaaatagc gaacttgagg acctaaaagc aacacattta cttcttttgt tgctacaatt
     5281 tcttctgctt caggagctgg aactgcaaaa atttctgcat ccaacccctt atcttctgct
     5341 gccttttgca tctttgtcac tagcagactt gtactcatac ctgctgcaca tgctaacata
     5401 attgttactt tagccatagc ttactccttt atcacctatt tactgaccta gccaagcgag
     5461 atactgtatg tctcactcct ctaattgcct tgctcaatgc ataaatatta tcgactgttg
     5521 ccagtccccc atatcctgcg tcacctatat gttgaatatc aactccacaa attttatttc
     5581 taagtgcaat ttccttgata gtatctgtat cagatgtttc ttggctagta ccaatagcac
     5641 tcaatacaag accaccctta ctatgaacga gatcaacgac ttcacgcaac tcttggtcat
     5701 gaaaggctgg aacggttcca actgctggaa caagtatcac atccgcacct gcttccaaca
     5761 attgctctgc gacagaaagc tctgccacag gctcattcac tcctgccccg tgcattttac
     5821 cagctataat caaacctgag aaattctctt tagcagattg aactgctttg ataatctctt
     5881 gattgctaac tcctgttcca ggatttccag tcaaacagac aaagtcaaaa cctaactcct
     5941 ctattcgatt caatgtttca acactagcaa cacgacctgc aacaatttcc tgtgtttcct
     6001 ctagcatctt tgcagatggg tcaatcggtt ccaaatttac accaattgga caagcaacaa
     6061 gctggtgtaa gcgatgaata acatcatcac ctgaactatc caaagcataa attttaggct
     6121 caaaaacatc aacacaattc aataaaatca tatcagctcc aaaagctcta gcaatttcag
     6181 aattagttat atccccaaca aatgtctcac gagtaactac attttcagat agaacaactc
     6241 taccttcact tgctaaaata ctttgtttta attcttcagc attcatctgt aatatctcag
     6301 atggatttgc actaattaaa cgtttcattc tcaatcctcc aataacttaa accgtttttc
     6361 aatagctatt acaaatggta aataaagtaa gacatccaaa acaatcaata caatttgtaa
     6421 taatgaacca gaaatacttc ctgtagcaag taaaccactt ataacaggtg gcatagtcca
     6481 acctggatct gtataagtta gcggaaccaa acctgatgcc attgctcccc acgctactag
     6541 taagttaaac attggagcta agataaatgg aactagtaac aaaatgttca aaacaatagg
     6601 aacgccaaac attgctggtt catttatatt aaataatcca ggtataacag ttataggtgc
     6661 caaagttttt agttgtttac tagctttctt cttatgtgct aaatatccta acgcaagaac
     6721 taaacctatg gttgcaccac cgccacctat gaatacaaaa ttatccataa atacgctagt
     6781 aaaaatattt ggaagagttt ctccagtttg ataagctact ttatttgcat ctagattagc
     6841 taaccataac ggtttcataa ctgcattaac aacatttcct ccgtgtaatc ctacaaacca
     6901 aaaactacta ttaaggaaaa ttaagataag aagaccaata acattatttc ctaaaagtcc
     6961 aagtggacct cccaaagcta cttgagcaat ttcatgaaga ttaggtaaac ttaatttatc
     7021 taaagttgca taaacaatca accaaccaac aatagtcact gcaccaggaa taatggcact
     7081 aaagctttta gatactgctg gtggaacacc atccggcatt tttatctgta tattatgatt
     7141 tataaaccat tggtagatat agccattaat caatcctaaa atcatagcaa caaataaacc
     7201 ttttgatgcc atgaaagcgg taggcattcc tgctccagcc tctcctgtaa tgaaaggcgt
     7261 aactgtaata aaagatgata atgacacaat accagcagga ataccatcaa ctttgtattg
     7321 tctagccata aagtaagcga taccaaaact agctacaaga ccaagtaatc caaaactact
     7381 atcaacaccc ttccataaat agtcagcaac accaatatca cccagatatt tttcccatcc
     7441 tggaatagga aaacttgcaa taaccattag taatgaacct atcaacaata aaggtatagt
     7501 tagagtaata ccgtctcgaa tagaaaccaa cgctttatta ttacccaatc tagccgctac
     7561 tggaagtaac ttttcttgta ataatttttc cataaccttt tcctcttaaa tatattttat
     7621 tatcaaaagt tatcaattat ctttattttt tgacgtcaag ttgttatttg attatctttt
     7681 gttatttata ttttacaact ataagaaagc cttgtcaagg atttgtgtaa atatttgatt
     7741 attttttatt atcaatatat aataaaaaga gaccagtaag caatgaaaag cttaaaaaga
     7801 ttaacatcta catttatcca tagcaaaaaa tcataggatt ttaagaatct gacaactagg
     7861 aagaaaacta atatgacctt atctaagaaa caattacaac taagagctaa aatactggaa
     7921 acagtttaca cattaggtcc catttcacga attgaaatcg ctactaaaac aggaataaca
     7981 cctgcaacaa ctagcagtat cacaaatgat ctgattaaag aaaatattct cttagaactt
     8041 ggtgaagacg aacacgatac aagcgtaggg agaaaaaaaa tcctgctaga cattcaagct
     8101 aaacgatttt actacattgg ttgtgaacta tctgaaaaac atttcacttt tgctttagga
     8161 gataatctag gaaatatctt aaaggaagag aaagaaattg ttactaaaca gttaatccaa
     8221 gaaaagggaa atcaactcat taaccagaca ctaaagcaat tcttaaataa ctgctctgat
     8281 tatgaaatag aagcaattgg aatcgcgcta cctggtcgct atttagataa ttataaaata
     8341 acaacaaaca atcctttatg gcaacatatc gacttagaaa tgattcaatc ccactttgat
     8401 aagcctttgt ttttctctaa caatgttaac tgtatggcta taggtaaacg cctatttagt
     8461 cgccaacaga atgaccctaa ttttgcttat tttcattttg ctagaggtat gcactgttct
     8521 tatatctacg acggaaacat ttatgggaaa ggaaatctaa tgattggaga aatagggcat
     8581 acagttgttt catctgaggg agaagaatgt agctgcgggc gcaagggatg cttacaaact
     8641 tttgctggag aatcttggtt aatcaaaaaa tcaaaaattc tatatcatca atctccctat
     8701 tctctacttc ctagtttagt caaaaatgcc gatgatattg atatccaagt tattttaacc
     8761 gcttatcaat taggtgacac tggaataatc acacttatcc atcaagcctt actctatctt
     8821 agtcaaacca ttttaaatat cagtatgatg attgactctc aaaaaatcta cctacatagt
     8881 cctttactaa caaatcaaca catcatccaa aaactatata gtgaaatgaa ctacaaaccc
     8941 aaactgctct ataatcgcct acctgaagtc attattgaac cttacaatga ttttacagcc
     9001 gcacactcag ctattgcact ttgtttgtat catacaattc tacattctta attttctatt
     9061 acatttaata aataggctaa aaagagggag tatatcataa aaagcgaata aacctgtttt
     9121 ctgaaaatca gaattctgtt ttgttcgctt tctttatatt tggaattata ctcctatctc
     9181 ccctttttca taatgtataa taaaatgaaa taataacagg acgaatcgct cgggacagtc
     9241 aaatcgattt ctaacaatgt tttagaagta gaggtgtact attctagttt caatctacta
     9301 tattttcgta caggtgcttc aaccatttga acgatttcaa atccttcttt ttggtaaaga
     9361 ttctgagctc tttgatttgc ctcgaagaca tttagagaaa tactatctat atcttcattt
     9421 tcaaaggcca aactaacaaa tttccttaaa gcctggctac ctaagtcttg ctcctgtttc
     9481 tgggggttga taaaaaatct cccgatatga agattgctgt cttctagcct gattttctgg
     9541 ataagtccca caaactcttg ttcatcaaag attgaaaaga ctccttccaa ggcttgaagg
     9601 gtcagtagaa aaggaatcct tggtcccatc cattgttctt gaaaggattt gcctagggag
     9661 ttggaccact ggcatacaaa ttgagcgttt tctatactca ccttttcttc aaaacgaatt
     9721 gtcatctttt cctcaccatc ttatctatgt ttctccatta tactatttct cccatttttt
     9781 acgaatagat aagtatgatt gatttttatt tttttctcgt cgggagcatt ctcgcttcct
     9841 ttcttggttt ggtcattgac cgttttccag agcaatccat tatcagttca gccagtcact
     9901 gcgattcctg tcagactcgc ttgcgtccct tagatttgat tccgattctc tcacaggtct
     9961 tcaatcgctt tcgctgtcgc tactgcaaag ttcgctatcc tgtctggtat gccctctttg
    10021 aattagtctt aggactcctc tttctgcttt actcttggga attgctttcc ttggggcaag
    10081 tcgtcctaat caccgctggt ttgaccttgg gtatctacga ctttcaccat caggaatatc
    10141 ccttactggt ctggatgact ttccacctaa tcctaatagc ttcctctggc tggaatctgg
    10201 tcatggtctc cttccttgct cttggaattt tggctcattt tatcgatatc cgcatgggcg
    10261 caggagattt cctcttttta gcttcttgtg ctctcgtctt tagcgtaacg gagttactga
    10321 tcttgattca gtttgcttct gcgacgggta tcctggcctt tatcctgcaa aagaaaaagg
    10381 aaagacttcc tttcgtgcct ttcctcttac ttgctacttg tttgattatt tttggtaagc
    10441 tactgcttgt ctgataaaat ccaatttctg ccatatgtcc ttcatgaaat tatttcacag
    10501 ttaaattata aattatttct tttgtacaaa gggatgatgt tatcaaatcg atctgttctt
    10561 ctatcttctt gatactgatc aaaaaatttc atttcgactg aaaatatttc gcttataaac
    10621 tgtaaacaaa tactttgttt agacattata gtcgctagac tgactagatg attactcaaa
    10681 acgacgtcca gaatactctt tactttgctt ggttttttaa caaaaatttg atcatccaaa
    10741 ggttcaatca ttttgtaacc tttttgcgca atttgacgat aaaagtaaga atgttgcttt
    10801 ggagtcaata atcctaactt aaaagctcga tactctaaag cctgtatcga aacattcaaa
    10861 tccgacttca ataaaatata actatcagga ttgctggcac gcttgccaac cctctcttca
    10921 aatttgacta aaaactcttc ttttggcaat aaaaaacatg atgcaaaata atttgcttct
    10981 tgctccaaac gatcgccatc ttcattcata tccttatatt tatgtaaaag aatatgtcct
    11041 agctcatgag ctaagtcaaa atttcgacgt acagatgatt tattcgttcc caacacaata
    11101 taaggtcttc ccaattttga ccatgcgcta taagcatcag cttggccatt aattaatcgt
    11161 tccacgatat agatacctga acgttctaat ttataaagca aatcatgatt atcttttgaa
    11221 atacctaatt tttccctggc ataaagagcc aattcctcaa tggattctcc cttatgataa
    11281 gattcactca ctacattact taggtcatga attataatat taggtataat tacaaaactt
    11341 tcaaaataat caatcaaact atctacctta tgtaaataca tagtttgaat atctattgtt
    11401 ttccgtgttg ctaggtctgc atttctaaag gcaattacag aagaatcaaa tcgaatgctc
    11461 tcttcttcct gttcaaaata agttaaatca acatgaaatt ggttggccaa atgcattttg
    11521 gttgataatt taggtttcgt ttcgttggac tcaaactgcc aaatggcttg ttccgttaaa
    11581 ttaattctct gagctaattc tgctctactt aaaccattta acagccgtaa ttctttcaat
    11641 acccgaccat taaacattta tatactcctt actacttttg accttcttgt ttttctattc
    11701 ttggaataat ttcaaaatct tctgtttccg ataattctga aaaattagga atatcttgat
    11761 atttagcttc ttcgaaatgg tacgaacttg attgaatata ctcagacaaa tcttgaatca
    11821 agtgtagctg accagttcgt gcatcaggca taacaacatc tacagatata atattgtttt
    11881 ctgagtccgc ctcataagtt aaaatcataa atttttcgat attcgaattt ttagtagctt
    11941 gttcaatttc ttgaatcatt tcatcagaaa ctaactccat ctgaattgga aaggaatgac
    12001 tatcttcatc atttttgtag gaagaatgtt gattaagata aagtgtattc atctgagcgt
    12061 attcaaataa gtagccactc ttattttttt gtaccaaagg aaattggttc gtaagtcgct
    12121 tcttaccctt tataattaac aatactttcc catatttttc tgtatttgtt tcaaattcta
    12181 aatatcccca agtctgtcct gctaattgta atttatactc aaacaaatct gctgatgcaa
    12241 atgcagtatc aatatgatta ggtcgcgtcc atgcataacc attcgacact atcattgtct
    12301 ctcttttttc tagacgttca tctacataat ctttttgccc tttcatcaaa gtatctacaa
    12361 ttttttgtgc ctcaagcgaa tcaaagagat cctgattcaa cataattctt cctcctccaa
    12421 atacttttta atgaattata tcattttctt aaagaaatta ctacaataat tatctttttc
    12481 ttaaagttct gtgtcagagt aatttagaaa attatatctt ctatagtaaa atcaattaaa
    12541 aactgaacaa atttattggg aaattcaaat cgctttctga aaatatttta ggaaccgtag
    12601 tgtaatattc cagattcaat tcactataaa actgaccttt ctcctgcaaa agaaaaagga
    12661 aagacttcct ttcgtgcctt tcctcttact tgctacttgt ttgattattt ttggtaagct
    12721 actgcttgtc tgataaaatc ctgaatcggc tctccttggt ggagagcttt tactattttt
    12781 gaaccgacga taacaccatc tgacaccgca ttgaagcgtt ccagatcggc ttgactagat
    12841 acaccaaaac ctgtcaagac tgggatgtcg gccacttgat gaagttgcgc caagtgcttg
    12901 tccaaatctg cacggtaatt gcctgatttc cctgtcaccc cattgatggc aacggcatag
    12961 acgaatccct ccgcccctgc aatcaactct ttctggcgct caattcctgt ggtcaagctt
    13021 actaaaggaa tcaaggcgat atctgtatct gccaaaaatg gttctacaaa gttggcatgt
    13081 tcatgaggca agtctgggat aatcaagccc ttcacagctg tatcagccag atctttgaca
    13141 aagttctcca caccgtactg aaagaggggg ttgaagtagg tcatgatgac cagtggaatc
    13201 tctgtttcaa tggttttcaa ggtttcaact aaagcctggg tagaggtccc gtgggctaaa
    13261 ctgcgcaagc cagcttcttc gataacaggt ccatctgcaa cagggtctga aaagggaata
    13321 cccacttcaa tagcagagac acccaaatct tctaaaaagt gaattgtttc agcaagaccg
    13381 tccaaacctt tctcgtggtc accagccatg atatagggaa cgaaaattcc ttttccagtt
    13441 acttttatag cattcaattt ttctgttagt gtcttaggca tgagcttctc ccttctttgc
    13501 tgcatctgct tccaagcggt ctttgacttg aaccacatcc ttgtccccac gacctgatag
    13561 gcagacaatc atagactttt ctggtccaag ttctttggcc aatttcaccg caaaggcgat
    13621 agcatggcta gattccaagg ctgggataat cccttccaca cgagacaaga gttggaatcc
    13681 ttccaaggct tcttcgtctg tcacagggac atagctggca cgtttaatat cgtggtagtg
    13741 agaatgctct ggaccgatac caggatagtc caaacctgct gagatagaga aggcttcaag
    13801 aatttgacca tgggcatctt ggagcacatc catgagggaa ccgtgaagga cacctggacg
    13861 acccttggtc aaggtagctg cgtggtgctc cgtatccaca ccaagtccag ccgcttcagc
    13921 tccatacatg gctactgact catcttctac aaagggatgg aagagaccaa tggcattcga
    13981 cccaccacca acacaggcta ctagggcatc tggcagattt tgtcctgtca agtcacggta
    14041 ctgttgttta gcctctcgac caatgacact ttggaagtca cgaacaattt ctggaaatgg
    14101 atgaggcccc aaggcagaac caaggatata gtgggtatca tctatattag ccacccatga
    14161 acgaagagct gcattgaccg catccttgag cacgcgcgaa ccatctgtca cggcctcgac
    14221 cttagctccc aaaagctcca tacggaagac attgagggct tggcgtttga catcttcctc
    14281 acccatgtag atggtacatt ccatgttaaa gagggccgca gcagttgcag ttgccacacc
    14341 gtgctgacca gcaccagttt ctgcgataat tttcttttta cccatacgtt tggcaagcca
    14401 aacttgtcct aaggcattgt taatcttgtg ggctcctgta tggttaaggt cttcccgttt
    14461 gagataaatc ttggctccgc cgatatgctg ggtcaagttt tttgcgtagt aaaggggagt
    14521 ttcacgtccc acatactggc gcaaaagttg gtttaattcc tcttggaaac ttgggtctgc
    14581 ctgactttca cggtaggcct tctccaactc caaaactgct gtcatcaatg tttctgggac
    14641 aaaacgtccg ccgaattttc cgtaaaatcc atctttattt ggttcctgat atgccatgct
    14701 ttaccctctc tataaatctt ctaatctttt catgatcttt ttgtccatct gtctccactc
    14761 cgctcgatac atctactgca tagggagtaa aatgttgaat tgcttttact acattatctt
    14821 cattaaggcc acctgcgata aagaagggct gtgctagtcc agtcgtatcc agttgacccc
    14881 aatcaaagga ctgaccactt cctgccacag gggcatcaaa gagtagataa tctgcctgag
    14941 aattggggac atgcccattt ccatctacct gcacagcctg aatactggca caaggcaaat
    15001 tctcaaataa atcatctgcc acctgaccgt gaacttgaac caagtccaag ctaactttgt
    15061 caatcgcttc cagcagttct acccgacttg gtgaaacaaa tactccaacc tttttcacat
    15121 ctgcaggaat aagctttgcc aactcagctg cctcttctaa agtcacctgt cttttactag
    15181 gtgcgaagac aaaaccgata tagtcggctc ctgctgaaac ggctgtttcc accgcttctt
    15241 tggtcgatag tccacaaatc ttaacctttg tcaatctgca actccttgat tctctggacc
    15301 acattttctg cctgcataag agctgtccct accaaaattc cgttaaagta tggggctagt
    15361 cgttccgcat cctgccctgt gaaaatggca gattcagaaa tgtaatagcg accttcctca
    15421 aagtaagggg ctaaatctac actggtctgc aagtcgacct caaaggtagt caagttgcgg
    15481 ttgttgaccc cgataatctc agcaccaagt ctgtgggcta cctctagttc agctagattg
    15541 tgagtctcca ctaagacttc cagaccaagc tctgtcgcgt agtcgtaaag ttccttaaga
    15601 cgttcttctg ccaaggctgc cacaatgagc aagataactg tcgcacctgc attgcgagcg
    15661 cggataattt gcttttcatc tatgataaag tctttgttga gcgtcggaat ctctacctga
    15721 ctggaaattt cccgtagata atccaaatgc cctttaaaga aaacctcatc tgtcaacacc
    15781 gaaatcatca ctgctccgtt ttcttcataa gtctgggcct gttgcacaat atccacatcg
    15841 agattgatat ctcccaaact agggctagct ttcttgacct cagcgattac ctgcaagcgg
    15901 tcctgatgat tcttcaaaaa ttctgccaag cgataggtct ggcgcagagg ctggatttgc
    15961 tccagcttca tctgctccac ctcacgcgcc ttctgctcta agattcgtgc taaaaattcc
    16021 tgactcattt ttggtactcc tgtaacagtc tgagtttttc aagggccttg cctctagcaa
    16081 tcacttgacg ggccaaggca actccttcct tgatgctatc aatcttacca ttagcataga
    16141 aaccaagacc agcattcaag actgtcgttt ccaagaatgg acttgcttcg tttttcagaa
    16201 cgctaagcaa aatttctgca ttttcctgag cattcccacc acgaatatct tccatagcat
    16261 agccttccat tcccaaatcc tctggagtaa agcttgacaa gctgatttcg ccattttcaa
    16321 gaagtgcaat cttggttgtt ccgttcaagc cagcttcatc caacccttct ggtccagcaa
    16381 ccacgatggc acgtttgcga cccatatttt tcaaaacctg agctgtactt tctaggagtt
    16441 ctggacgact aattccaaga agctgtgttt ctaaagccat tggatgaatc agtggaccag
    16501 tcaagttcat aatcgttgga attcccaatt ccaaacgagc tggcatgatg tatttcatag
    16561 ctgggtgcat atttttagcg aagagaaaga cgattccagt tttatcaaag accttaccta
    16621 gttcagctgg tttgaggtca agattgattc ccaaggcttc gaggacatct gcggaaccag
    16681 atttagaaga aatcgagcgg ttaccatgct tggccatgtg aataccgcca ccagccaaga
    16741 caaaggctgc agttgtggaa atattaaaac tgaaagactt gtccccacct gtaccacagt
    16801 tgtccatggc atcatgaatc tcagttggaa tatgctgggc atgtcctctc atgacttggg
    16861 caatggctgt gcgttcttca ggtgtttccc ccttcatctt aagagctaag aggagagaag
    16921 caatctgcgc ttcagttaca cgcccagtta cgatacgctc aatgacatcc gtcatttcca
    16981 cacctgataa attttcaaat tttgctagtt tttcaataat ctctttcatc ctagtttcct
    17041 cactttacaa ccttctcgat aaaattccga atagaagaca agccgtctgg cgttccaatg
    17101 ctctctggat ggtactggaa gccataaatc ggtaggtttt tatgttgaat ccccatgatg
    17161 gcttggtcat cagtcgaacg agctgtcact tcaaagtctt ctggcatttc ctcaatcaaa
    17221 atactgtgat aacgcatgac cgcacgtcct tcctcaatac cttgatacaa aacagatggc
    17281 gcttcaaagt tgatattgct ctgtttccca tgcatgactt ttggagccaa acctagctta
    17341 ccaccaaaga cttctgcaat ggcttggtgg cccaaacaaa tccctagaat cggcttcttg
    17401 cctgcaaaat cacgaatcat gtcttccatc tttccagcat caactggcca accaggacca
    17461 ggagaaaaga ccagaccatc tgctttttca gcttcttcat acagcttgga atcatcattt
    17521 ctcagaacct gaacttctgc aaaattccca atgtattggg ccaagttata ggtaaaagaa
    17581 tcatagttgt caatcaataa aatcatggtc ttagttctcc aattctagtc atagattttg
    17641 ttttgttaat ggtttcttgg tattcgtttt gggcgataga gtcgtagaca atccctgccc
    17701 cagcctgcac ataagctctt tgatttttga gaatcatggt tcggatggcg atggccaaat
    17761 ccatatcacc cgtcgcagac aagtagccga ttgctcctgc gtatacgccc cgtttttctg
    17821 tttccagttc atagatacgt ctcatagctc gaatctttgg cgctccagaa acggttccag
    17881 caggaagcgt tgctttcaag gcatccatag cagtgagttc tggaagcaaa cgccccttga
    17941 ccacgctggt caaatgcatg acgtagcgga agagctccac ttccatatac ttagtgactt
    18001 ggacactggt cgtttcagag atgcggccaa tatcgttacg ccccaagtct accaacattc
    18061 gatgttctgc tgtttccttc tcatcagaga ggaggtcagt cgccaaggcc ttgtcttctt
    18121 catccgtagc ccctcttggt cgcgtccctg caatcggatt ggttgtcacg atgccatttt
    18181 tgacagaaac caaactttct ggactggctc cgatgatttg ataatcccca aagtcatata
    18241 aatagaggta attggatgga ttggtcacgc ggagatttct gtagaagtca aatggatttc
    18301 cagtaacttc tgctgagaag cgctgactga gtacacattg gaacatatcg ccattacgaa
    18361 tcaagtcgcg agcggtttcc accatttcct caaatttatg tggagcgata tgcggtttga
    18421 agtctaacgg agatagatcc aagtcttcaa attcatttgg agcaggaatg cgtaattcct
    18481 caagcacttg gttcaaggat ttttccaagg cctcttgact gcgctcacta taaagtgcat
    18541 cctctatgac atggattttt tccttcttgt ggtcaaagac catatagctc tcatagacaa
    18601 agaaatgcat gtctggcgtc ccaattgtat cctcagggat ttgaccaatt tcttcataaa
    18661 gcgaaatcat atcgtaaccc acaaaaccaa tggctccacc accaaaaggt agctctgagt
    18721 ggtgctgact cttatgaatc acttcataaa ggaaatccaa gggatcccga tcaatcactt
    18781 gaccattttg atagagaact ccattttcaa acttaatctc aaaaactgga ttataggcta
    18841 ggatagaaaa acgagctgtt tccttgtctc tcggaatact ctctaaaata accttatgtt
    18901 gcccctttaa gcgcatataa gccaagattg gtgataagac atctccatga atgattcgtt
    18961 ccattgtaat ttccctttca gttctacttc tagtcagtgg tgactgtatg aaaaatcccc
    19021 acgcaaaata acttgcgtga ggacgaaatt cgcggtgcca cctcaattat aggatttctc
    19081 ctatctctca ttcctgtctc agatatctcc tgtaacaggc tgtgcgataa agggcactcc
    19141 cttgagaatg atgttttctt ctctcgtttc agatgaaccc aactttacag ctttctctgc
    19201 ttgttttcag caaccacaag ctctctgtga gagaaagaac tgtaattttt ccatctatta
    19261 ttttttagct tctagtagtc tgcaatcgca gctaggtcct tgcctccacg accagagaca
    19321 ttgatgaaga gatgttcatc tcggtacatc tttatactct tcgaacaact cttcaaaccg
    19381 cgtcaacgtc gccttgccgt aggtatggtt actgacttcg tcagttctat ccacaacctc
    19441 aaaacagtat tttgagctga cttcgtcagt tctatccaca acctcaaaac agtgttttga
    19501 gcaacctgcg gctagtttcc tagtttactc tttgattttc attgagtatt actagctttt
    19561 ttcgtattag tccagccttt ttgtttgctt ttagtagtag gcaaggagct gtagatagaa
    19621 ctcaagttca tcaaagcgac ttaaggccct aataaaagat aaaccaaacg acggatagaa
    19681 aaaagcccac acacagaata tacttccgtg tgagggcgtt ggtaacgcgg tgccacctca
    19741 attataaagg gactatccct ttacatctct gccttgttta acaacaagct gcactgtaag
    19801 gtgtgcgcac cgaattttca ttgtttcaaa ttcattttca aaatcagccc actttcacta
    19861 cttccaacca cctattcaca atcaccacag gctccctgaa gatcaaaaat agttactttt
    19921 ctgatttgtt gaacttattt taatactttg ttttttcttt gtcaagactt ttttacgatt
    19981 tttttgaaaa tatcattcga atatgaccat gtcttcctta gatcgaacat gaacatgtcc
    20041 cacttgttag aaattggatc caactcaata gaaactgaat ggaggctaaa cagaacttat
    20101 tttagaacac tccatctttt ccactaggat tttcaagaat taaacaatac tagaaactct
    20161 gtctcctaac aaatttagga gaaacttcaa cagatgtgac actttcccct ttaataattg
    20221 ctaaaacacc ttctatcatt tctttagcca atttaacata attgggagca attgtagaca
    20281 aagctggagt ataatactga gaaataggaa tattatcaaa tccaatgata gaaatatcat
    20341 ctggaataag aattcctttc tcatagcacg cacgaatcaa gccctgaacc ttttcatctc
    20401 ctgaaacaaa aataatgtcc ggataatttt gggtagtcaa gtgctgcatt gcataagaat
    20461 aaactgaatc aattgtagat aagccataaa tgacttttaa atccataaag taatttttat
    20521 cattcagaaa agaacgcaca cctctttcac gatccttatt aacatgggat tctcctccca
    20581 taagcaacca catattttta aatttttctt cagttacagc tttcatcata tcataagtag
    20641 cttgaaaatt attattagat acatagacta ctccagacgt ttgagattca ccgaaaacaa
    20701 gaaaaggcat atggttcttc tttaaatact gaattctgat atcatctaca ctttcataaa
    20761 aaacaataac accatctact aggctacctg tgcttgatat aattgaatta ctaattgtat
    20821 cctcctctcc aaagtactca actatagcat taacaccaaa ttctttacac gtccgtaaca
    20881 ctttatctaa cagcgtatga aaccaaatta aaggaaaaga gtcgattttt tttacagaaa
    20941 tcaatatatt tatagcttct tttttagtta aattttttgc atacgcattt ggaatatacg
    21001 acaattcctc tataactttt tgaatcgctt gataagtttc ttctttaaca tttactccac
    21061 cattaataac tcgtgaaact gtttttggag aaaaacctga taaacgtgca atatcataaa
    21121 tagttacctt tttcccattt atatttttca tttcagtcct ccattacgaa cattctaata
    21181 ttactataca atatttaatt ttttttaaca agagaattta gtaaattatt taagatccac
    21241 aaattcacaa aattaatttt acaaatattc tttcccttca aaaaagttta aattgcattt
    21301 cacaccttta tttttaagaa tgtttccaac ttcacgacaa ataaattcat atgagaaaaa
    21361 actgccataa aattgtagat taactttttc agtaaaatgt gtaggattta taaaaacata
    21421 taatagcctg tcaatgtaac attttaacat agagttaatt ttttctttaa agataacatt
    21481 tgttatcaac tcatcaagag gtaaatgaaa ggcaaacacc atttcacaaa tatcataaaa
    21541 agaaataaat ttgtatactt gtatcaaaca attattatca aatattctat tttacctaaa
    21601 tcaaaattga ttttataatc tttcataaaa acctctgagc aaaaatctac tcaaaaatta
    21661 gatgattaaa acatct
//
LOCUS       DAVHKZ010000035        21296 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000035 DAVHKZ010000000
VERSION     DAVHKZ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21296
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.035"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            250..1695
                     /gene="cps4A"
                     /locus_tag="VVO74_001663"
     CDS             250..1695
                     /gene="cps4A"
                     /locus_tag="VVO74_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEU5695659.1"
                     /translation="MSRRFKKSSSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     IDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVLEIDDSSLAVVKAAIQDVMEGR"
     gene            1697..2428
                     /gene="cps4B"
                     /locus_tag="VVO74_001664"
     CDS             1697..2428
                     /gene="cps4B"
                     /locus_tag="VVO74_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HEU5695660.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRIIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            2437..3129
                     /gene="cpsC"
                     /locus_tag="VVO74_001665"
     CDS             2437..3129
                     /gene="cpsC"
                     /locus_tag="VVO74_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEU5695661.1"
                     /translation="MKEQNTIEIDVFQLFKTLWKRKLMILIVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRDQGDKPGLTNQDLQAGSYLVKDYREIILSQNVLEKVATNLKLD
                     MPTKTLASKVKVTVPTDTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLQIP
                     LLGVVPDLNKMK"
     gene            3139..3828
                     /locus_tag="VVO74_001666"
     CDS             3139..3828
                     /locus_tag="VVO74_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEU5695662.1"
                     /translation="MPTLEISQAKLDFVKKAEEYYNALCTNLQLSGDDLKVFSITSVK
                     LGEGKSTTSTNIAWAFAHAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNVENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEVGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            3844..5211
                     /locus_tag="VVO74_001667"
     CDS             3844..5211
                     /locus_tag="VVO74_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU5695663.1"
                     /translation="MNGKIVKSSLAIIQSFLVILLTYLLSAVREAEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGCFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     gene            5242..6414
                     /locus_tag="VVO74_001668"
     CDS             5242..6414
                     /locus_tag="VVO74_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEU5695664.1"
                     /translation="MKQSVYIIGSKGIPAKYGGFETFVEKLTEYQKDGNIQYYVACMR
                     ENSAKSGFTADTFEYNGAICYNIDVPNIGPARAIAYDIAAVNKAIELSKGNKDEAPIF
                     YILACRIGPFISGLKKKIRSIGGRLLVNPDGHEWLRAKWSLPVRKYWKFSEQLMVKHA
                     DLLVCDSKNIEKYIREDYKQYQPKTTYIAYGTDTTPSSLKSEDAKVRNWYREKGVSEN
                     GYYLVVGRFVPENNYETMIREFIKSKSNKDFVLITNVEQNKFYDQLLKETGFDKDLRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     DGAIYWKKDELAHVIEEVERFDEGDITELDEKSSQRIADAFTWEKIVSDYEEVFTV"
     gene            6411..7694
                     /locus_tag="VVO74_001669"
     CDS             6411..7694
                     /locus_tag="VVO74_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU5695665.1"
                     /translation="MKILHYTLGFQPSRTGGLVKYAEDLMTQQATDGHEVIALYPGEI
                     SIIFRQVRIKKAENRKFQCYKIINSLPLALFGGISEPDEFMKSCDKASYRKFLKNIKV
                     DVIHIHSLIGLHKEFIEVAKELGIKTVFTSHDYYGLAPVPHFYFNGVDYSSNNTNLAW
                     NIMSSNALSVKKLRFFQVSFYPTIRKLMKMLGKNPKSKKNLVIRDITEAIDYSALRSY
                     YKAMFGLIDAYLFNSQLAKEVYEANHIIPKNNIIVSISNSSISNHNIRVSSGEKTVVA
                     YIGPDEEYKGYFDFLDIVNDLDQEKYDIKTYGHFPNEDCPPYIQQNGYFTKDTVGSVY
                     SNIDILIVPSRWKETFGLISIEALSYDVNVFVSKNVGSKDLVSEEHIFHNKDDLLKKI
                     QYVKFENVKFKTMKEHMVEIINYYERITNDNQKIN"
     gene            7672..8361
                     /locus_tag="VVO74_001670"
     CDS             7672..8361
                     /locus_tag="VVO74_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HEU5695666.1"
                     /translation="MIIKRLIKTITGKEIDLHPDIPITYILQRGFQYGLGLSRGLLRG
                     IGLGKKGKRLFIGRGVTLLAKRKLYVGNNIRIGKYVSIDCLSKDGIQIADNVKIGDYS
                     QIIGTGSVKNMGIGLKIGKNSSFSEYSLFGSAGGITIGGDVIAGQNVRFHAENHSYEV
                     LHIPIREQGVNRKGISVGDNCWIGAGAVFLDGSSIGSGCIVATNAVVTKKFPDNVIIG
                     GVPAKILMERK"
     gene            8405..9640
                     /locus_tag="VVO74_001671"
     CDS             8405..9640
                     /locus_tag="VVO74_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU5695667.1"
                     /translation="MKIAVVGTGYVGLSISVLLAQHHHVVAVDIVKEKVELINKRISP
                     IQDDFIERYLSESNLDLVATIDAETAYKDASFIVVATPTNYDLERNFFDTSTVESVIQ
                     QVQNMNSTATIVIKSTVPVGFTDSIRKKLGISNLLFSPEFLRESRALYDNLYPSRIIV
                     GTDLSNQKLVEKAQVFSNLLVQGAIKKDIPILTMGFTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEIKGLDTQKIIEGVSLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYKNVPE
                     ELIGAIVRSNTTRKDFIANQVLKVVNYNIPEDDIPTKQMEKEVVIGIYRLTMKSNSDN
                     FRQSSIQGVMKRIKDRGVKVIIFEPTLKDSDTFFGNAVINDLEEFKVKCDVIIANRYD
                     ETLNDVKDKVYTRDIFRRD"
     gene            9591..10772
                     /locus_tag="VVO74_001672"
     CDS             9591..10772
                     /locus_tag="VVO74_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU5695668.1"
                     /translation="MTLRIKYIHEIFLEEIDKNMKKVLIVRSGPYQVNPEGYNLQELG
                     LASAISQQGYQCDVMYYHKTKNYDQLYEKNGEQIKIFWRRGIRLFRSGIYPQILREKF
                     LNQYDKIIISEYSQIMAVLLSRIHSNVYIYNGPYYNLFKIPIIEPIYDFLFVEMLNKR
                     TKTVFCKTEKAECYLKNKGFNDCKVVGVGLDIEKFEQEEEPTEDTIELLRRMENKQNI
                     LYVGSLSKRKNTAQLIRIFNILKSKSGKKNELQLVLIGKDEDNIVEKINYSRFKDDII
                     YQPYLKNSQLQFIYPSSQLLVLPSVQEIFGMVLLEAMYFKLPVVSSASAGGETLIQDG
                     INGKIVNDFNDEHWVDCIENLLNNPLELKRLGECAHKRITEQFMWSSIARKIIETFDE
                     R"
     gene            10781..11623
                     /locus_tag="VVO74_001673"
     CDS             10781..11623
                     /locus_tag="VVO74_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU5695669.1"
                     /translation="MNFCFVILHYRTSNDTIECIKSIQKLEGDYKIVIVDNASQNGSI
                     ERVEALFANNDEIVIIKNTKNLGFAAGNNIGYAYARTQIKADMIAVLNNDIVIKQKDF
                     INRIFELYRNSQFHIAGPDIVSLVDGHHQSPVVEKINSISKANKELFKYRILRIINKI
                     GLYELMTRQPKKELNRISVADPMRYQENVILHGSFVIFSPLYVSEEECAFRPDTFMYM
                     EEPILYEYCMLKNYKTVFDPSIVIYHKEDSSTNSLYNAAYAKREFVFKNMIRSLKIYR
                     SLLK"
     gene            11665..12933
                     /locus_tag="VVO74_001674"
     CDS             11665..12933
                     /locus_tag="VVO74_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HEU5695670.1"
                     /translation="MLALTIGTVVFVKKTYRTFLNPIILFVILWFIITTLSSLKLFQL
                     FEISTHTQQIILLGTSLFVIGGGIAIWFRDKFYFKVGGNSYFTTDFEINYNLFFLLGI
                     ICLFYYLPDFFSSLVSLIRGGNLNLVRQSAQDAVDTSGLKNFIGTFIVSPSAMVLEIL
                     GVLDFWSNKKGRKLFYLSLAVIFVRVIADAGRTPLFNVVIYLLLTVLANRFSEKTEKK
                     RKVSKIKIVNYGMLGSIILWLSTLSRTTTSVYRILYFYFAMSPILLEKWSSVLDSEKL
                     VTKGLVSLNGFFFSISYVLKNLFRIDYSQRVLEAYTMIANTDAIWYNIAPGLTKANAY
                     VSLFWFFYADGRLLGVLIGSLLYGTFCGYIFCRYIQQQNKKNLAMLLFIYQGVFFSFI
                     RFPFSKSNYAIAFVLLLFFAFKKKGIEKSV"
     gene            12926..13933
                     /locus_tag="VVO74_001675"
     CDS             12926..13933
                     /locus_tag="VVO74_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695671.1"
                     /translation="MFNINDQSIIYVACPYFNKTGGTELVHQLVYSINHFGGKAIVAY
                     YGSESAPNKVNPAFREYVSTFVDIKDVIDSLDNIIILPEINPDLAANLESIQKAVWWM
                     SVDNYLKRNGILGSLEHFGLLRTIKLFVKGNIKIGGYRIDKEIPHLYQSEYAKQFLLA
                     KGVKKYYRLSDYLNESYIQRSISTDTKKDVILYNPKKGIEFTRELIKQAPELTFSPIE
                     NMSTEQVKKLLSKSKVYIDFGNHPGKDRFPREAAISGCCVITGKRGSAKYYKDIPIPD
                     SYKFEDTVENIPNIIETLKSCLKNYDKHTVDFEKYQQYIKSEHDLFERDVKELFTRNR
                     G"
     gene            13938..15380
                     /locus_tag="VVO74_001676"
     CDS             13938..15380
                     /locus_tag="VVO74_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000107550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HEU5695672.1"
                     /translation="MSTRNSLIKNSLYNVAYRMLNIIFPLVSATYTARIILASGVGEV
                     SFAQNVVSYFTTIAAMGIPNYGIREIAKTRNKAEATNKVFSELFLINGLSTLLCSIVY
                     LILILTFNSIFDNTSMYLAVGLTLVFNFLNIDWFYQGKEDYAYITKRSFSIKLISLFS
                     LFIFVRDTDDAVNYALISSLAIGGNNIFNLVNLRKYNIRFSFNNIKIRRHLKPIFVLL
                     GSVIAIEIYTMLDTTMIGAMVGTTEVGYYTNSMKLVKLLITVITAIGGVLLPRLSDYY
                     SKGEFEKLNHIVDKVFRIMLFLFLPAQVALILVAPVIMPILFGDSFIPAVLTLQLTSL
                     LICTLGFSNLFGTQILLTFGDERKLLISTILGALSNIALNLILIPVMAQNGAALASVI
                     SETIVTLTAYYYAKKRVTIRFDLGFYLPTVVSTIIMGGAIYVVMQLYIGDIEKMLFST
                     LLGGVVFLLINVFMKNPIIYEFTGIIKRKR"
     gene            15383..16483
                     /gene="glf"
                     /locus_tag="VVO74_001677"
     CDS             15383..16483
                     /gene="glf"
                     /locus_tag="VVO74_001677"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HEU5695673.1"
                     /translation="MYDYLIVGAGLSGAIFAHEATKRGKKVKVIDKRDHIGGNIYCEN
                     VEGINVHKYGAHIFHTSNKKVWDYVNQFAEFNNYINSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKIAEQTAGMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     IELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFAHRE
                     ELEASANKVVFTGMIDQYFDYKHGELEYRSLRFEHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGMQPKTVITHEYPADWKRGDEPYYPINDEKNNAMFAKYQEEAAQNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFSN"
     gene            16510..17379
                     /gene="rfbA"
                     /locus_tag="VVO74_001678"
     CDS             16510..17379
                     /gene="rfbA"
                     /locus_tag="VVO74_001678"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEU5695674.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLTLAQPLKKN
                     EYGQYLLRLIGEA"
     gene            17380..17973
                     /locus_tag="VVO74_001679"
     CDS             17380..17973
                     /locus_tag="VVO74_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018029578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEU5695675.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDL"
     gene            17986..19035
                     /gene="rfbB"
                     /locus_tag="VVO74_001680"
     CDS             17986..19035
                     /gene="rfbB"
                     /locus_tag="VVO74_001680"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEU5695676.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            19101..19952
                     /gene="rfbD"
                     /locus_tag="VVO74_001681"
     CDS             19101..19952
                     /gene="rfbD"
                     /locus_tag="VVO74_001681"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEU5695677.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            20015..20485
                     /locus_tag="VVO74_001682"
     CDS             20015..20485
                     /locus_tag="VVO74_001682"
                     /inference="COORDINATES: protein motif:HMM:NF013739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding protein"
                     /protein_id="HEU5695678.1"
                     /translation="MYDYLVVGAVFAHEAALEGKKVKVIEKRNHIAGNIYTREEEGIQ
                     VHQYGAHIFHTSDKEIWDYVNQFAEFNRYTNSPVANYKGEIYNLPFNMNTFNKLWGVV
                     TPAEVQAKIDEQRAILNGKTPENLEEQAISLVGTDIYEKLIKDYTEKQWGQTNY"
     gene            20451..20627
                     /locus_tag="VVO74_001683"
     CDS             20451..20627
                     /locus_tag="VVO74_001683"
                     /inference="COORDINATES: protein motif:HMM:NF015247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695679.1"
                     /translation="MQRNSGGKPTTELPSFIIRCLPVHLTYDNNYFNDTYQGIPIGGY
                     TQIVEKCWIMKILM"
     gene            20603..21188
                     /locus_tag="VVO74_001684"
                     /pseudo
     CDS             20603..21188
                     /locus_tag="VVO74_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835598.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
BASE COUNT         6984 a         3257 c         4433 g         6622 t
ORIGIN      
        1 aagattatac cacattgtgt actatattat attgaaacta gaatagtaca catctgcttc
       61 taaaatattg ttagaaaacg atttgactgt cctgatcaat ttgtcatgtt cttatttcat
      121 tttactatat ttttggttcg cgggaagtct actaagatac ttaaagatgc agatagtgaa
      181 aataaaggtg tagacattac cgtaaaaaag tgatataatc gtatgatgtt caatgtatag
      241 gtgttaatca tgagtagacg ttttaaaaaa tcaagttcac agaaagtgaa gcgaagtgtt
      301 aatatagttt tgctgactat ttatttattg ttagtttgtt ttttattatt cttaatcttt
      361 aagtacaata tccttgcttt tagatatctt aatctagtgg taactgcgtt agtcctacta
      421 gttgccttgg tagggctact cttgattatc tataaaaaag ctgaaaaatt tactattttt
      481 ctgttggtgt tctctatcct tgtcagctct gtgtcgctct ttgcagtaca gcagtttgtt
      541 ggactgacca atcgtttaaa tgcgacttct aattactcag aatattcaat cagtgtcgct
      601 gttttagcag atagtgagat cgaaaatgtt acgcaactga cgagtgtgac agcaccgact
      661 gggactgata atgaaaatat tcaaaaacta ctagctgata tcaagtcaag tcagaatacc
      721 gatttgacga tcgaccagag ttcgtcttac ttggcagctt ataagagttt gattgcaggg
      781 gagactaagg ccattgtctt aaatagtgtc tttgaaaata tcatcgagtc agagtatcca
      841 gactatgcat cgaagataaa aaagatttat accaagggat tcactaaaaa agtagaagct
      901 cctaagacgt ctaagaatca gtctttcaat atctatgtta gtggaattga cacctatggc
      961 cctattagtt cggtgtcgcg atcagatgtc aatatcctga tgactgtcaa tcgagatacc
     1021 aagaaaatcc tcttgaccac aacgccacgt gatgcctatg taccaatcgc agatggtgga
     1081 aataatcaaa aagataaatt aacccatgcg ggcatttatg gagttgattc gtccattcac
     1141 accttagaaa atctctatgg agtggatatc aattactatg tgcgattgaa cttcacttct
     1201 ttcttgaaaa tgattgactt attgggaggg gtagatgttc ataatgatca agagttttca
     1261 gctctacatg ggaagttcca tttcccagta gggaatgtcc atctagactc tgagcaggct
     1321 ctaggttttg tacgtgaacg ctactcacta gccgatggag accgtgaccg tggtcgcaac
     1381 caacaaaagg tgattgtggc tatccttcaa aaattaacgt caaccgaagc actgaaaaat
     1441 tatagtacga tcattaatag cttgcaagat tctatccaaa caaatatgcc acttgagact
     1501 atgataaatt tggtcaatgc tcagttagaa agtggaggga attataaagt aaattctcaa
     1561 gatttaaaag ggacaggtcg gacggatctt ccttcttatg caatgccaga cagtaacctc
     1621 tatgtgttgg aaatagatga tagtagttta gctgtagtta aagcagctat acaggatgtg
     1681 atggagggta gatgaaatga tagacatcca ttcgcatatc gtttttgatg tagatgacgg
     1741 tcccaagtca agagaggaaa gcaaggctct cttggcagaa tcctacaggc aaggggtacg
     1801 aatcattgtc tctacctctc accgtcgcaa gggcatgttt gaaactccgg aagagaagat
     1861 agcagaaaac tttcttcagg ttcgggaaat agctaaggaa gtggcgagtg acttggtcat
     1921 tgcttacgga gctgaaattt actacacacc agatgttctg gataagctgg aaaaaaagcg
     1981 gattccgacc ctcaatgata gtcgttatgc cttgatagag tttagtatga acactcctta
     2041 tcgcgatatt catagcgcct tgagcaagat cttgatgttg ggaattactc cagtcattgc
     2101 ccacattgag cgctatgatg ctcttgaaaa taatgaaaaa cgcgttcgag aactgatcga
     2161 tatgggctgt tacacgcaag taaatagttc acatgtcctc aaacccaaac tttttggcga
     2221 acgttataaa ttcatgaaaa aaagagctca gtatttttta gagcaggatt tggttcatgt
     2281 cattgcaagt gatatgcaca atctagacgg tagacctcct catatggcag aagcatatga
     2341 ccttgttacc caaaaatacg gagaagcgaa ggctcaggaa ctttttatag acaatcctcg
     2401 aaaaattgta atggatcaac taatttagga gaaatgatga aagaacaaaa cacgatagaa
     2461 atcgatgtat ttcaattatt taaaaccttg tggaaacgca agctaatgat tttaatagtg
     2521 gcacttgtga caggtgcggg ggcttttgca tatagcactt ttattgttaa gccagaatat
     2581 acgagtacca cgcgaattta cgtagtgaat cgcgatcaag gagacaagcc ggggctgaca
     2641 aatcaggatt tgcaggcagg atcttatctg gtaaaagact accgtgagat tatcctttcg
     2701 cagaatgtat tggaaaaagt agcgacaaat ttgaagttgg atatgccaac aaaaacgtta
     2761 gccagcaaag ttaaagtgac tgtaccaact gacactcgta tcgtctcaat ctctgtcaaa
     2821 gataaacaac cagaagaagc cagtcgtatc gctaattctc tacgagaagt tgctgcagaa
     2881 aagatcgtcg ctgtaacgcg agtatctgat gtaacgacac ttgaagaagc gcgaccagct
     2941 acgactccct cttctccaaa tgttcgacgc aattccttgt ttggttttct tggaggagca
     3001 gtcgtaacag taattgctgt tcttttgatt gagttgctcg acacccgtgt gaaacgtcct
     3061 gaagatgtcg aagatgtact gcaaattcca cttttagggg tcgttccaga tttgaacaaa
     3121 atgaaatagg aggaagttat gccaacatta gaaatctcac aggcaaaatt ggattttgta
     3181 aaaaaggcag aggaatatta taacgctttg tgcacgaacc tacagttaag tggagatgat
     3241 ttgaaagtat tttctatcac ttctgtgaaa ctaggagaag gaaaatcaac gacttccacc
     3301 aatatcgctt gggcttttgc gcatgcaggt tacaaaacgc tgctgattga tggagatatt
     3361 cgcaattctg ttatgttagg tgtctttaaa gcaagggata agattacagg cctgacagaa
     3421 tttttatcag gaactacaga cctatcacaa gggctttgtg ataccaatgt cgaaaatctc
     3481 tttgtaattc aggctggctc tgtgtcaccg aatccgacag ctcttcttca aagtaagaat
     3541 ttcagtacaa tgcttgaaac cttgcgtaaa tattttgact acatcattgt agatactgct
     3601 cctgtcggtg tcgtgattga tgcggctatt attacgcgaa aatgcgatgc ttctatttta
     3661 gtgacggagg taggtgaaat aaatcgacgg gatattcaaa aagcaaaaga acagttggaa
     3721 cacacaggaa agccgttttt gggagttgtg ttgaataaat tcgatacttc agtagacaaa
     3781 tacggttctt atggaaatta tggagattac gggaaaaata aaaaataggt cgggggatta
     3841 gagatgaatg gaaaaatagt aaagtcttca ttggccataa tccagagttt tcttgttatt
     3901 ttattgactt atctacttag tgctgtgaga gaagcggaga ttgtttcaac aacagctatt
     3961 gcactttata tcctccatta ttttgtcttt tatatcagtg attatggaca ggatttcttt
     4021 aaaagaggat atttgattga acttgtccag acattgaaat atatcctatt ctttgcacta
     4081 gcgattagta tttctaattt tttcttagag gatcgattta gtatttccag acgaggcatg
     4141 atttacttcc tcacattaca tgctctctta gtctatgtgc taaacctatt tatcaagtgg
     4201 tattggaagc gggcttatcc caactttaaa ggaagtaaga agattctcct acttacagca
     4261 acttctcgtg tcgaaaaggt actggataga ttaatagaat caaatgaggt tgttggggag
     4321 ttggtagccg tcagtgtctt agataaacca gattttcagc atgattgttt aaaggtagta
     4381 gcagaggggg agatagtaaa ctttgcgact catgaggtgg tcgatgaagt ctttatcaat
     4441 cttccaagtg aaaaatacaa tattggagag cttgtctctc agtttgaaac gatgggaatt
     4501 gatgtaacag ttaatctaaa tgcttttgat cgtagtttgg cacgtaacaa gcaaattcgt
     4561 gagatggcag gattaaacgt tgtgactttt tctacaacat tttataagac tagtcatgta
     4621 attgctaagc ggattattga tatcatgggt gcattggtag ggctgatact atgtggttta
     4681 gtcagtattg tactggttcc tttgattcga aaggatgggg gctctgctat ttttgctcag
     4741 acgcgtatag gaaaaaatgg tcgtcagttc actttttata agtttcgctc tatgtgtgta
     4801 gatgccgagg cgaaaaaaag agaactcatg gaacaaaata ccatgcaggg tggaatgttt
     4861 aaggtggacg atgatcctcg tatcacgaaa attggttgtt ttatacggaa gactagcttg
     4921 gacgagctac cacagtttta taatgttcta aagggagata tgagtttggt tggcacacgg
     4981 ccaccaacag tggacgagta tgagcactat accccagaac aaaagcgtcg tctgagtttt
     5041 aaacctggca taacagggtt atggcaggtc agcggacgaa gtgagattaa gaattttgat
     5101 gaagttgtca aattagatgt agcctatata gacgattgga caatttggaa agatattgaa
     5161 attttattga agacagttaa agttgtattg atgaaggatg gagcgaagtg atttttgccc
     5221 ttcggtcttg ttaggagaga tatgaaacag tcagtttata tcattggttc aaaggggatt
     5281 cctgccaagt atggaggatt tgaaaccttt gttgagaaat taacagaata tcaaaaagat
     5341 ggtaacatcc aatactatgt tgcttgcatg cgcgaaaatt ctgcaaagtc aggatttaca
     5401 gcagacacat ttgagtacaa cggtgctatt tgttacaaca ttgatgtgcc taatattggt
     5461 cctgctagag ccattgctta cgatattgca gcggtcaata aggctattga attgtctaag
     5521 ggaaacaagg acgaggctcc cattttttac attctagctt gtcgtatcgg accttttatt
     5581 tctggactta agaaaaaaat tcgttcgatc ggaggccgtt tgctggtaaa tccagatggt
     5641 catgagtggc ttcgagctaa atggagcttg ccagttcgga agtattggaa attttcggaa
     5701 cagttgatgg tcaaacatgc agatttatta gtctgcgata gcaaaaatat cgaaaaatat
     5761 attcgagagg actataaaca gtatcagccc aagacgacct atatcgctta tggtacagat
     5821 actacccctt caagtctgaa atcagaagat gccaaagttc gaaactggta tcgtgaaaag
     5881 ggagtaagcg aaaatggcta ttatctagtg gtgggacgat tcgttcccga aaacaactat
     5941 gaaaccatga ttcgtgaatt tatcaagtct aagtccaata aggactttgt ccttattaca
     6001 aatgtggaac agaataaatt ttacgatcag ttgctcaagg aaacaggttt cgacaaggat
     6061 ctaagagtca aatttgtggg aacagtctat gaccaagaat tgctcaagta tatccgtgaa
     6121 aatgctttcg cctatttcca tggacatgaa gttgggggta ccaatccatc gcttcttgaa
     6181 gctttagcat ccactaaact caacttgttg ttggatgtcg gctttaaccg tgaagttggt
     6241 gaagacggag ccatttattg gaaaaaagat gagctagcgc atgtaatcga agaagtggaa
     6301 cgatttgatg aaggtgatat tacggaatta gacgaaaagt ctagccaacg aattgcggat
     6361 gcatttacgt gggaaaagat tgtgtcagat tatgaggaag tgtttactgt atgaaaattt
     6421 tgcattatac tttaggcttt caaccatcac gtacaggtgg tcttgtcaag tatgctgagg
     6481 atttgatgac tcaacaagct acagatggac atgaagtaat cgcattatat ccaggagaaa
     6541 tctcaattat atttaggcag gttagaataa aaaaagcaga gaatcgaaaa ttccaatgct
     6601 ataaaataat aaacagccta cccttggctc tatttggtgg tatttcagaa ccagatgaat
     6661 ttatgaagag ttgtgataaa gcttcttata ggaaattttt gaaaaatatt aaggtagatg
     6721 taattcacat tcactcgctt ataggattac ataaggaatt tattgaagtt gcaaaagaat
     6781 taggaattaa aactgtattt acaagccatg attattatgg tttagcgcca gttccgcatt
     6841 tttattttaa cggagtagat tatagtagta ataatactaa tttagcatgg aacatcatgt
     6901 cctctaatgc tcttagtgta aaaaaacttc gattctttca agtctctttt tacccaacaa
     6961 ttcggaaatt gatgaaaatg cttgggaaaa atccaaagtc caagaaaaac ttagtaattc
     7021 gtgatatcac ggaggctatt gattatagtg ctctccgctc ttattataaa gcaatgtttg
     7081 ggttaataga tgcttacctt ttcaatagtc agttagctaa ggaagtttat gaagctaatc
     7141 atataatacc taaaaacaat atcatagtgt ccatttctaa cagctcaata agtaatcata
     7201 atattcgtgt tagttccggt gagaaaacag tggtagctta tattgggcct gatgaggaat
     7261 ataaggggta ttttgatttt ctagatatag ttaatgattt agatcaggaa aagtatgata
     7321 ttaaaacata tggacatttt ccaaatgaag attgtccacc ttatatccaa cagaacggtt
     7381 atttcacaaa agacacggtt ggaagcgttt attccaatat agatattttg attgtgccga
     7441 gtaggtggaa ggaaacattt ggtttgatta gtatagaggc gctatcgtat gatgtgaatg
     7501 tttttgtgag caaaaatgtg ggctctaaag atttggtttc agaagaacat atctttcata
     7561 ataaagacga tttgttaaaa aaaattcaat atgtaaaatt cgagaatgta aaattcaaaa
     7621 cgatgaaaga gcatatggtg gagattataa attactatga aaggattaca aatgataatc
     7681 aaaagattaa ttaagacaat tacaggtaaa gaaattgatc ttcaccctga tatcccaata
     7741 acttacattc ttcagagagg ttttcaatac ggtttgggtc ttagtcgagg gttgttacgt
     7801 ggtattggtc taggaaaaaa aggcaaacga ttatttattg gacgtggggt aacccttctc
     7861 gcaaaacgca agttatatgt tggaaacaat atccgaatcg gcaaatatgt gagcatagat
     7921 tgcctttcaa aggatgggat ccaaattgcg gataatgtta agataggaga ttactcgcaa
     7981 ataattggta caggttcagt aaaaaatatg ggtattgggc tcaaaattgg aaagaactct
     8041 tctttctcag aatatagttt attcggttct gcaggtggga ttactatcgg aggagatgtt
     8101 attgctggac aaaatgtacg ttttcatgct gagaatcata gctacgaagt gttgcatata
     8161 ccaatcagag agcaaggtgt taatcgtaaa gggatatccg ttggtgacaa ttgctggatt
     8221 ggggcaggag ctgttttttt agatggatct agtatcggtt caggttgtat cgttgcaacg
     8281 aatgcggttg ttactaagaa atttccagat aatgtaatta ttggtggagt gccagctaaa
     8341 attttaatgg aaagaaagta gtattaaatt aattgtataa atggagggaa atgatatgtc
     8401 taaaatgaag attgctgtag ttgggacagg ttatgttggt ttatccattt ctgtgttact
     8461 tgcacaacac catcatgtag tagcagtaga tattgtaaaa gagaaagtag aattaattaa
     8521 taaaagaatt tcacctattc aggatgattt tattgaaaga tatctttcag aaagtaattt
     8581 agatttagtt gcaacaatag acgctgaaac agcttataaa gatgcctctt ttatcgtagt
     8641 agcgacacca acaaattatg acttagaaag aaattttttt gatacatcaa cagttgaatc
     8701 ggtcattcaa caagttcaga atatgaattc tacagcaact atagtaataa aatcaacagt
     8761 ccccgtgggc tttaccgatt caattcgtaa aaaattagga atttcaaatc ttctattcag
     8821 tcctgaattt ttgcgtgaat caagggcact ttatgataac ttatatccaa gtcggatcat
     8881 agttggaaca gatttaagta atcaaaaatt agttgaaaaa gcccaagttt tctctaatct
     8941 tttagtgcaa ggtgccatta aaaaagatat ccctatttta actatgggat ttactgaagc
     9001 tgaagcagtt aaattatttg ctaataccta cttagcattg cgggtatcat attttaatga
     9061 attagatact tatgcagaga tcaaagggtt agatactcaa aaaataattg aaggtgttag
     9121 tttagatcct cgtatcggaa cccattataa taatccgagc tttgggtatg gtggatattg
     9181 cttaccaaag gatactaagc aacttttagc caattataag aatgtcccag aagagcttat
     9241 tggagctata gtacgaagca atacaacacg taaagatttt attgctaatc aagttcttaa
     9301 agtggtgaat tataatatac cagaagacga tattcctact aaacagatgg agaaagaagt
     9361 tgttattgga atataccgat taactatgaa aagtaacagt gataactttc gtcagagttc
     9421 aatacaagga gttatgaaac gtattaagga tagaggagtt aaagtaatca tttttgagcc
     9481 tactctaaaa gatagtgata cattctttgg aaacgctgtt ataaatgatt tagaagagtt
     9541 caaagtaaag tgtgatgtga ttattgcaaa tcgttatgat gaaacgttga atgacgttaa
     9601 ggataaagta tatacacgag atatttttag aagagattga taaaaatatg aaaaaagtat
     9661 taattgttcg aagtggacct taccaagtca atccggaagg atataatctt caagaacttg
     9721 gtttagcctc cgctatcagt cagcaaggct accagtgtga tgtcatgtat tatcacaaaa
     9781 caaagaacta tgatcaatta tatgagaaaa atggggaaca aattaaaata ttctggagga
     9841 ggggaataag attatttaga agtggaattt atccccagat tttaagagag aaatttttga
     9901 atcagtatga taagataatt atttctgagt acagccagat tatggcagtt ttattgtcta
     9961 gaattcattc caatgtatat atttataatg gcccatacta taatctattt aagattccca
    10021 ttattgaacc tatatacgat tttctttttg tagaaatgct caataagaga accaaaacag
    10081 ttttctgcaa gacagaaaaa gcagagtgtt atcttaaaaa caaaggattc aatgattgta
    10141 aagtagtggg cgtaggtcta gatattgaga agtttgaaca agaagaggaa cctacagagg
    10201 atactataga gcttttaaga agaatggaga ataaacaaaa tattctttat gtaggttcac
    10261 tatcaaaaag aaaaaacaca gctcagttaa ttagaatttt taatatttta aaatctaaaa
    10321 gtggtaagaa aaatgaactt caattggtat tgattggtaa ggatgaggat aatattgttg
    10381 aaaaaattaa ctattcacgg tttaaagatg atattattta tcaaccttat ttaaagaatt
    10441 ctcagcttca atttatttac ccatcatcac aactacttgt gctcccgtca gttcaagaga
    10501 tttttggtat ggtattactt gaggcaatgt attttaagtt gcctgttgtt tccagtgcaa
    10561 gtgctggagg agagacactg attcaagatg gtataaacgg taaaattgtg aatgatttta
    10621 atgatgaaca ctgggtggat tgtatagaaa atctattaaa taacccattg gaattgaaac
    10681 ggcttggaga atgtgctcat aagcgcatta cggaacagtt tatgtggtct tcaattgcga
    10741 gaaaaataat tgagacattt gatgaaaggt aagacttgct atgaattttt gttttgtgat
    10801 tttgcattat cgtaccagca atgacactat agagtgtatc aaatcgattc aaaagcttga
    10861 gggagattat aaaattgtaa ttgttgataa tgcttctcaa aatggcagta tagaaagggt
    10921 agaagcctta tttgcaaata atgacgagat agttataata aaaaacacga aaaacttagg
    10981 atttgctgct ggaaataata ttggatacgc ctacgctagg actcaaataa aagctgatat
    11041 gattgctgta cttaataatg atattgttat taagcaaaaa gatttcatca atcgtatatt
    11101 tgaactctat agaaattctc agtttcatat cgctggtcca gacattgtct ctcttgtaga
    11161 tggtcatcat caaagtcctg ttgttgagaa gattaattct atatctaagg ctaataaaga
    11221 actttttaaa tatagaatct tgaggattat taataaaata ggattatatg agctgatgac
    11281 tagacagcca aaaaaagaat taaatagaat aagtgttgca gaccctatga gatatcagga
    11341 aaatgttatt ttacatggga gttttgtaat tttttcaccg ttgtatgttt cagaggagga
    11401 gtgtgctttc agaccggata cattcatgta tatggaagag cctattctat atgaatattg
    11461 catgcttaaa aattataaga cagtatttga tccttctatt gtaatttatc ataaagagga
    11521 ctcatcaaca aattcgttgt ataatgcagc atatgcaaaa agagagtttg tttttaaaaa
    11581 tatgattaga tctctaaaga tttatagaag tctattgaag tagtaaacta aggaaaggat
    11641 aataattaga aattgaatct tagtatgtta gccttgacaa taggaacagt ggtatttgtt
    11701 aaaaaaacgt ataggacgtt tctcaatccc ataattttat ttgtaatttt gtggtttatt
    11761 ataacaactt tgtcaagttt aaaactattc caacttttcg agattagtac tcacacacaa
    11821 caaattattt tgcttgggac ttctctattt gttatagggg gagggatagc aatttggttt
    11881 cgggataaat tttattttaa agttggcggt aactcatatt ttacaacaga ctttgaaatt
    11941 aattataatt tgttcttttt gctaggtatc atttgccttt tctattattt gccagatttc
    12001 ttttcctcac tggtatcatt aataagaggt gggaatttaa acttagttag acaatctgcg
    12061 caggatgcag tagataccag tggattaaag aatttcattg gaacatttat tgttagtcct
    12121 agtgccatgg tattagaaat attaggagta ttagatttct ggagcaataa aaaaggtaga
    12181 aaactatttt atcttagttt agctgtcatt tttgtaagag ttattgcaga tgctggtaga
    12241 acacctctat ttaatgttgt catatattta ttacttactg ttttagcaaa taggttctct
    12301 gaaaaaactg aaaagaagag aaaagttagt aaaattaaga tagtaaatta tggtatgcta
    12361 ggttcaatta tcttatggct atcaacttta tctaggacaa caacctccgt ttataggatt
    12421 ctttattttt atttcgcaat gtccccaata ttattagaaa agtggagtag tgtacttgat
    12481 tctgaaaaat tagtaacaaa gggtttggtt tcgttgaacg gtttcttttt ttcaatctca
    12541 tatgtactta aaaatctgtt tagaatagat tattcgcaaa gagtattaga agcatacaca
    12601 atgattgcga atactgatgc aatctggtat aatattgcac ctggtttgac caaggcaaat
    12661 gcatatgtct ctctgttttg gttcttttat gcggatggac gtttactagg agttttaata
    12721 ggatcccttc tatatggtac cttttgtggt tatatctttt gcaggtatat ccagcaacaa
    12781 aataaaaaga atttggctat gttactattt atttatcaag gtgttttttt ctcttttatt
    12841 agatttccgt tttcaaaatc aaattatgca attgcattcg tactcttatt attttttgct
    12901 tttaagaaga aaggaataga gaaaagtgtt taatatcaat gaccagtcta ttatttatgt
    12961 tgcatgtcct tattttaata aaacaggtgg aacggagctt gtccatcaat tagtttattc
    13021 tattaatcat tttgggggga aagctatcgt tgcttattat ggtagtgaaa gtgctccaaa
    13081 taaggtgaat cctgcgttta gagaatatgt ttctacgttt gttgatataa aagatgttat
    13141 tgactctctt gataatatta ttattttacc ggaaattaat ccggatttag ctgctaatct
    13201 agagtctatt caaaaagcag tatggtggat gagcgttgac aattatttga agcgtaatgg
    13261 tattttaggt tccttggaac attttggact tttacgaaca attaaattat ttgtaaaagg
    13321 aaatattaaa ataggtggat atagaataga taaagagatt ccccatcttt atcaaagtga
    13381 atacgccaag caatttcttc tagctaaagg tgtcaaaaag tactatagat tgtctgatta
    13441 tttaaacgag tcttatattc agcgatctat ttcaacagac actaaaaaag atgttattct
    13501 ttacaatcct aaaaaaggga ttgaatttac tcgtgagcta attaaacagg ctccagaatt
    13561 aacgttctct ccaattgaga atatgtcaac tgaacaggtg aaaaaattac tttcaaaaag
    13621 caaagtatat attgattttg gcaaccatcc tgggaaagat agattcccac gggaggcagc
    13681 gatatcaggt tgttgtgtga taactgggaa acgaggttct gcaaaatatt ataaggatat
    13741 tcctattcca gattcataca aatttgaaga cactgttgaa aatatcccca acattattga
    13801 gaccctgaaa tcatgcttaa aaaattatga caaacatact gttgactttg agaaatatca
    13861 acaatatatt aaatctgaac atgatttatt tgaaagagat gtgaaagaat tattcactag
    13921 gaataggggt taaggttatg tcaaccagaa attcacttat taaaaattct ctttataatg
    13981 ttgcttatag aatgttaaat atcatatttc cattagtatc cgcaacatat actgcacgga
    14041 taattttagc tagtggagtt ggggaggtct cgtttgcaca aaatgttgtt tcttacttta
    14101 caacgatagc tgctatgggt attccaaatt atggtatacg agaaattgct aaaactagaa
    14161 ataaagcaga ggctacgaat aaagtttttt cagagctatt tctgattaat ggattgtcta
    14221 cattactgtg ttctatagta tatttaattc tgattttgac attcaatagc atttttgata
    14281 atacatcaat gtatcttgct gtgggtttaa cattagtgtt taacttcctt aatatcgatt
    14341 ggttctatca aggaaaagag gactatgcat acatcacgaa acgtagtttc agtataaaac
    14401 ttatttctct ttttagttta tttatttttg ttagagatac tgacgatgca gttaactatg
    14461 cattgatttc tagcttagca attggcggga ataatatttt taatcttgtt aatttaagga
    14521 aatataatat tagatttagt tttaataata ttaagattag aagacactta aaacctattt
    14581 ttgttttgtt gggttcagtg attgctattg aaatctatac tatgctggat accactatga
    14641 ttggtgctat ggtaggaacg actgaggtag gttattatac aaattctatg aagctagtta
    14701 aattgctgat aactgtgatt accgctattg gaggagtgct tttaccacga ctaagtgatt
    14761 attattctaa gggagaattt gaaaaattaa atcacatcgt tgataaagtt tttagaatca
    14821 tgttgtttct ttttttacca gcccaagttg cattaattct agttgcacca gtaattatgc
    14881 cgattttatt tggtgatagt tttataccag cagtgttaac acttcaactt acttctttgc
    14941 ttatatgtac attagggttt agtaatttat ttgggactca aatattacta acatttggag
    15001 atgagcgaaa gcttttgatt agcacaattt taggagcgct tagtaatatc gctttgaacc
    15061 taattctgat tccagtaatg gctcaaaatg gagcagcgtt ggcatctgtg attagtgaaa
    15121 caattgttac tttaacagca tactactatg cgaaaaaacg tgtgacaatt aggtttgact
    15181 taggatttta tttgccaact gttgtttcaa caataatcat gggtggagct atatatgtag
    15241 taatgcaatt gtatattggg gatatagaaa aaatgttatt ttcaactttg ttaggaggtg
    15301 ttgtattcct tttaattaac gtttttatga agaatcctat tatatatgaa tttacaggta
    15361 ttataaagag aaagagataa ttatgtacga ctatttaatc gttggagcgg gtttgtctgg
    15421 agcaatcttc gcacacgaag ctacaaagcg tggaaaaaaa gtaaaagtga ttgataaacg
    15481 cgatcacatt ggagggaaca tatactgtga gaatgtagaa ggtatcaatg ttcataaata
    15541 tggtgcccat atcttccata cttctaataa aaaagtctgg gactacgtca atcaatttgc
    15601 tgagtttaac aactatatca actcacctgt cgcaaactat aagggaagtc tttataacct
    15661 tcctttcaat atgaatacct tctatgctat gtggggcaca aaaactccac aagaagtgaa
    15721 ggataagatt gctgagcaga cagctggtat gaaggatgtt gagccgaaaa atctggaaga
    15781 acaagctatc aagttgattg gtccggatat ctatgaaaag ttgatcaagg gttatacaga
    15841 aaagcaatgg ggacgctcag cgatagaact tcctccattt atcataaaac gccttccagt
    15901 tcgtttaacc tttgataata actattttaa tgaccgttac caagggattc ctattggtgg
    15961 ttacaatgtc atcatcgaaa atatgctgaa agatgtagaa gttgaacttg gagtagactt
    16021 ttttgctcat cgtgaagagt tggaagcatc tgctaacaaa gttgtcttca caggaatgat
    16081 cgaccaatat tttgactaca agcacggaga gttagaatac cgtagccttc gttttgagca
    16141 tgagatttta gacgaggaaa attatcaagg gaatgctgta gtgaactata cagagcgtga
    16201 gatcccttat actcgtatca tcgaacacaa acattttgaa tatggaatgc agccaaagac
    16261 agttatcacg catgaatatc cagctgactg gaagcgtggg gacgagccct actatcctat
    16321 taacgatgag aaaaataatg ctatgtttgc taaataccaa gaagaagcag cgcagaatga
    16381 taaagttatc ttttgtgggc gtttagcaga ttataagtat tacgatatgc atgtggtgat
    16441 tgaacgggcg cttgaggttg tggagaaaga atttagtaat tgaaaaacaa cgaagaaagg
    16501 ttgcttatta tgaaaggtat tattctagca ggtggttcgg gaactcgctt gtatcctttg
    16561 actcgagccg catcaaaaca acttatgccg gtttatgata aaccgatgat ttactaccca
    16621 ctttcaacat taatgttggc tgggattagg gatattttga ttatctcaac tcctcaagat
    16681 ttgcctcgtt ttaaagagct tcttcaagat ggttccgagt ttggtattaa actttcttat
    16741 gctgagcaac caagtccaga tggtttggca caagccttta tcattgggga agagtttatt
    16801 tctgatgata gcgttgcgct aatcttaggt gataatatct accatggttc tgggctttcc
    16861 aagatgctac aaaaggcagc gagtaaggag tcgggagcaa ctgtttttgg ctaccatgtc
    16921 aaggatccag agcgctttgg tgtggttgag tttgatcagg atatgaaggc tatttctatt
    16981 gaagaaaagc cagagcaacc tcgttcaaac tatgcagtta caggtctcta tttctatgat
    17041 aatgatgtag tagagattgc caagagtatt aaaccaagtc ctcgtggtga actggaaatt
    17101 acagatgtaa acaaagctta cctagatcgt ggtgatttgt ctgttgagct tatgggacgt
    17161 ggctttgctt ggctggatac tggaactcat gaaagtttac tagaggcttc acagtacatc
    17221 gaaacagtcc aacggatgca aaatgttcag gtagcaaact tagaagaaat tgcctatcgc
    17281 atgggttata tcagtcgtga agatgtattg accttagccc aaccacttaa gaaaaatgaa
    17341 tacggacagt atctgctccg tttgattgga gaagcataga tgacagataa ttttttcggt
    17401 aagacgcttg cggcacgcaa ggttgaagct attccaggca tgttggagtt tgatatcccc
    17461 gttcatggag ataatcgtgg ctggtttaaa gaaaatttcc aaaaggaaaa aatgcttcca
    17521 cttggatttc cagagtcttt ctttgcagaa ggaaaattgc aaaacaatgt atccttctca
    17581 cgtaaaaatg tccttcgagg actccacgca gagccttggg ataagtacat ctctgtagca
    17641 gatggaggga aagttctggg ttcttgggtt gatctacgcg agggtgaaac ctttgggaat
    17701 acctatcaga cagtaattga tgcaagcaag ggaatctttg ttcctcgagg cgtagctaat
    17761 ggcttccaag ttctatcaga tacagtgtca tatagctatc tggtcaatga ttactgggct
    17821 ctcgagctca aacccaagta tgcctttgtg aactacgctg atccaagcct tggtattgaa
    17881 tgggaaaata ttgcagaagc agaggtttca gaagcagata aacatcatcc cctacttaag
    17941 gatgtaaaac ctttgaaaaa agaagatttg taaaaaggaa agaatatgac tgaatacaaa
    18001 aatattatcg tgacaggtgg agctggcttt atcggttcta actttgtcca ttatgtttac
    18061 gagaactttc caggtgttca cgtgacagtc ctagataagt tgacttatgc tggaaatcgc
    18121 gcgaatattg aggaaatttt aggtaatcgt gttgagttag ttgttggtga cattgctgat
    18181 gcggagttgg tagacaagtt ggctgctcaa gcagatgcta tcgttcatta tgcagcggaa
    18241 agccacaatg ataattcgct caatgatcca tcgccattta ttcatactaa cttcatcgga
    18301 acctatactc ttttagaagc tgctcgtaag tatgatattc gcttccacca tgtatcgaca
    18361 gatgaagttt atggggatct ccctttacgc gaagatttgc caggtcatgg tgaaggacca
    18421 ggtgagaaat ttactgctga aacaaaatac aacccaagct ctccgtattc atcaaccaag
    18481 gcagcctcag atttgattgt caaagcctgg gtgcgttctt ttggagtcaa ggcaacgatt
    18541 tccaactgtt caaataacta cggtccttat caacatatcg aaaaattcat cccacgtcag
    18601 attactaaca tcctaagtgg aattaagcca aaactttacg gtgaaggtaa gaatgttcgt
    18661 gactggattc ataccaatga ccattcttca ggagtttgga caatcttgac aaaagggcaa
    18721 atcggtgaaa cctacttgat tggggctgat ggtgagaaga acaataagga agttttggaa
    18781 cttatcctta aggaaatggg acaagctacg gatgcctatg atcatgtgac tgaccgtgca
    18841 ggacatgacc ttcgctatgc gattgatgcc agcaagctcc gtgatgagtt ggggtggaaa
    18901 cctgaattta ccaactttga agctgggctc aaggcaacaa tcaagtggta tacagataac
    18961 caagaatggt ggaaagcaga aaaagaagct gttgaagcca attatgctaa gactcaggag
    19021 attattacag tataaaaagc aggaaatagc tgctttttat tgctatattg agaagagtta
    19081 catattagaa aggtctagag atgattttaa ttacaggggc aaatggccaa ttaggaacgg
    19141 aacttcgcta tttattggat gaacgtaatg aagaatacgt ggcagtagat gtggctgaga
    19201 tggacattac caatgaagaa atggttgaga aagtttttga agaggtgaaa ccgactttag
    19261 tctaccactg tgcagcctac accgctgttg atgcagcaga ggatgaagga aaagagttgg
    19321 acttcgccat caatgtgacg gggacaaaaa atgtcgcaaa agcatctgaa aagcatggtg
    19381 caactctagt ttatatttct acggactatg tctttgacgg taagaaacca gttggacaag
    19441 agtgggaagt tgatgaccga ccagatccac agacagaata tggacgcact aagcgtatgg
    19501 gggaagagtt agttgagaag catgtgtcta atttctatat tatccgtact gcctgggtat
    19561 ttggaaatta tggcaaaaac ttcgttttta ccatgcaaaa tcttgcgaaa actcataaga
    19621 ctttaacagt tgtaaatgac cagtacggtc gtccgacttg gactcgtacc ttggctgagt
    19681 tcatgaccta cctagctgaa aatcgtaagg aatttggtta ttatcatttg tcaaatgatg
    19741 cgacagaaga cacaacatgg tatgattttg cagttgaaat tttgaaagat acagatgtcg
    19801 aagtcaagcc agtagattcc agtcaatttc cagccaaagc taaacgtccg ctaaactcaa
    19861 cgatgagcct ggccaaagcc aaagctactg gatttgttat tccaacttgg caagatgcat
    19921 tgcaagaatt ttacaaacaa gaagtgagat aagtagtaga atgattttct agtctaataa
    19981 aagaggcaga taatgaactc caaaggagct taagatgtac gattatcttg ttgttggtgc
    20041 agtctttgcc catgaagcag ccttagaagg aaaaaaagta aaagttattg aaaaacgaaa
    20101 tcatatcgcg ggtaatatct atactcgtga agaggaagga attcaagttc atcaatatgg
    20161 tgctcatatc ttccatactt ctgataagga gatctgggat tatgtaaatc agtttgcaga
    20221 gtttaaccgt tataccaatt ctcctgttgc aaactataag ggtgagattt ataaccttcc
    20281 ttttaatatg aataccttca ataaactctg gggagttgta acgccagcag aagtacaggc
    20341 taagattgat gaacaacgtg ctattttaaa tggtaaaact cctgaaaatt tggaagaaca
    20401 ggcgatttct cttgtaggta cagacatcta cgaaaaatta atcaaagact atacagagaa
    20461 acagtggggg caaaccaact actgaacttc catcctttat tattcgctgt ttaccagtac
    20521 acctgaccta tgataacaac tattttaacg atacctatca agggattcca attggtggat
    20581 acactcaaat agttgaaaaa tgttggatca tgaaaatatt gatgtagaaa caaatgttga
    20641 tttctttgtg aacaaagagc aatatctgaa agattttcct aagattgtct ttactggtat
    20701 gattgatgaa ttctttgact ataagttggg cgaactagag taccgtagtc ttcgttttga
    20761 aaatgagacc ttggatatgg aaaattacca aggaaatgca gttgtgaact atacggatgc
    20821 agaaacccca tatactcgca ttattgaaca caaacatttt gagtttggga gtcaagcaaa
    20881 gactatcatt actaatagaa cattctaaaa catgggaaaa aggtgatgag ccttattatc
    20941 cagttaataa tgatcgtaat aatcatttgt ataaatcata taaaaaactt gctgatgagc
    21001 aagggaatgt tatctttggt ggccgcttag gacactatcg ttattacgat atgcaccaag
    21061 taattggagc agctttgcag tgcgtgagaa atgagttaga ttcatactca atgaaaatta
    21121 aagagcaaac taggaagcta gccgcaggtt gctcaaaaca ctgttttgag gttgcagatg
    21181 gaagctgacg cggtttgaag agattttcga agagtataaa caagtaaaac tgactaccag
    21241 ttattattta gaaatagtat taaaaattcc ttgactatat gatatcccaa atcatt
//
LOCUS       DAVHKZ010000036        20314 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000036 DAVHKZ010000000
VERSION     DAVHKZ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20314
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.036"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            79..248
                     /locus_tag="VVO74_001685"
                     /pseudo
     CDS             79..248
                     /locus_tag="VVO74_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            448..3723
                     /gene="rexB"
                     /locus_tag="VVO74_001686"
     CDS             448..3723
                     /gene="rexB"
                     /locus_tag="VVO74_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU5695680.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMNFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYCFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            3720..7370
                     /gene="addA"
                     /locus_tag="VVO74_001687"
     CDS             3720..7370
                     /gene="addA"
                     /locus_tag="VVO74_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU5695681.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAANELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFMSHFVEVYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYIFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLTSLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7540..8718
                     /locus_tag="VVO74_001688"
     CDS             7540..8718
                     /locus_tag="VVO74_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695682.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERDIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            8927..15001
                     /locus_tag="VVO74_001689"
     CDS             8927..15001
                     /locus_tag="VVO74_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU5695683.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVSDKG
                     VPEVQPELPEAVVSDKGVPEVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPV
                     EKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQGAENPVQPAEESTTNSEKVSP
                     DTSSENTGEVSNKPSDSTTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSN
                     QETEKPVQPAEETQTNSGKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSG
                     NTTSENGQTEPEPSNGNSTEDVSTKSNTSNSNGNEEIKQENELDPDKKVEDPEKTLEL
                     RNVSDLELYSLSNGTYKQHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKND
                     KILYKITAKVEKLQQEIESRYKDNFPFYLAKKGTEETTNFTSFSNLVKAINQNLSGTY
                     HLGASLNANEVELSTDDKSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDSYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DRDAQIQDSYAEGDINNVKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKNEVVSKESFEERGTMLDASQIASKKAEI
                     NLITPPIVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKATIVKYGNLVK
                     ENSILYQKELLSAVMMKDDQVITDIISNKQTANKLLLHYKDHSSEKFDLRYQADFANL
                     AEYSIGDSGLLYTPNQFLYHQDSIINQVLPELNRVNYQSDAVRNTLGISPEVKLTELY
                     LEEQFTKTKEHLAENLKKLLSSDAGLVTDNEVMTGYIIDKIKRNKEALLLGMSYLERW
                     YNFSYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYAISLAS
                     HHGTTDLFSTLENYRKVFLPDKTNNDWFKSQTKAYIVEEKSNIEEVKTKQGLVGTKYS
                     IGVYDRITSATWKYRNMVLPLLTLPERSVFVISTISSLGFGAYDRYRNKEHQANGDLN
                     SFVEKSAHETAERQRDHYDYWYRILDEKGREKLYRNILLYDAYKFGTNHTEGKATEVA
                     DFDSPNPAMKHFFGPVGNKVGHNGHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHNS
                     DQDIYLGGYGRRSGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSKEGERLQVL
                     DPTTRFKDATDLQKYVHNMFDVVYMLEYLEGKSIVKKLNVYQKIEALRKIENQYLTDP
                     ADGNDVYATNVVKNLTEDEAKKLTSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAP
                     IFSALSGEKGTPGDLMGRRIAFELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGK
                     ERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPRYGTK
                     TINNVDELQKLMDEAVLQDAKERNYYYWNNYNPETDSAVHKLKRAIFKAYLDQTNDFR
                     RSIFENKK"
     gene            15045..>20314
                     /locus_tag="VVO74_001690"
     CDS             15045..>20314
                     /locus_tag="VVO74_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU5695684.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGTSTYHYLDYS
                     TLTQTERVQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVDYLELDDR
                     TVSPVEQPKVVTDKGEPEVQPALPEAVVTGKGKTEVQPTLPEAVVTEKGEPEVQPVLP
                     EAVVAEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVGTTGVDENGNLIEPPVN
                     DIPEYTEPISTVSEVASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDNSVKQVGE
                     DGERQIVTSYEELHGKKISESVETVTILKEMKPEIIVKGTKERPKEKTAPVLTLTKVT
                     EDAMNRSANLNYELDNKDNAEISSIVAEIKDGDTVVKRVDLSKEKLTDAVQNLDLFKD
                     YKIATTMIYDRGQGSETSKLDERPLRLELKKVEIKNIASTNLVKVNDDGTETPSDFMN
                     EKPSEEDVKKMYLKITSRDNKVTRLTVDSIEEVTEEGQKLYKITAEAQDLIQHTDPTK
                     VRNKYVYYIEKPHPKEDNVYYNFKDLVDAMNTDKNGTFKLGADLNATGVPTPKKWYVD
                     GDFRGTLKSVEGKHYTIHNTERPLFQNIIGGTVTKVNLGNVNINMPWADRIAPIADTI
                     KGGAKIEDVKVTGNVLGRNWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVG
                     ENWKGLVERAYVDANLIGKKAKAAGIAYWTQNSGDNHKVGVEGAVKKGIVKGTIQVES
                     PVEVGGAVGRLSHHGYIGEVVSMMKVKKGEIFYGSSDMNDDPYWVANNVRGNYVVNGV
                     SEGTISYARAKEHHRIKPISQSEADTKIMMLGITAQDFAINEPVVNRLNRLTRKEDEY
                     KSTQDYKVDRDLAYRNIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQF
                     VTDLSDIDKIMVHYADGTKEEMDVTKNADSKVKQVREYTIAGQNVVYTPNMVEKDRNQ
                     LIQDIKDKLASVQLISPEVRALMDARKKPEENTDERKNGYIKDLYLEESFAETKANLD
                     KLVKSLVENADHQLNSDEAAMKALVKKVDENKAKIMMALTYLNRYYDIKYGDMTIKNL
                     MMFKPDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNM
                     RLFTNDTDLNDWFIHAAKNVYVSEPQTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTL
                     KNAHMFLISTYNTMAYSSFEKYGKYTEEARNEFKKEIDKVAHAQQTYLDFWSRLALPS
                     VRDQLLKSENRVPTPVWDNQNYSGIKGINRMGYDEKKVPIAPIRELYGPTWKFHNTNW
                     NMGAMASIFPNPNNNDQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGHRHRQGTD
                     VEAYAQGMLQTPSSIGHQGEYGALGLNMAYHRENDGDQWYNYDPDKLQTREDIDRYMK
                     NYNEALMMLDHVEADAVLPQLNGDNSKWFKKIDREMRRNLGDGLNNLVAPHQWDNVRD
                     LNQEESSKKLSSINDLIDNNFMTKHGNPGNGRYRPEDFRPNSAYVNVNMMAGIYGGNT
                     SQGAPGSLSFKHNAFRMWGYYGYDKGFTSYVSSKYQGEADKQNQGRLGDDFIIKKVSN
                     NQFSNLEDWKKYWYHDVKSRAEKGFTEITIDGQTIHNYNELKDLFDKAVTEDLKKAGN
                     YSNTENLKSKVFKALLKNTDGFFNPLFKKD"
BASE COUNT         6904 a         3713 c         4231 g         5466 t
ORIGIN      
        1 tacgaaaatc tattgaatat gccataagaa gattatacca cattgtgtcc tatttttggt
       61 tcattttact atagttcaat cattctatca agaatattga atatataaag gcacgtaata
      121 ttaaaacttc ttctgatatc gaattagagt ccgatgttga tggcgataaa tcagacaatc
      181 tacccgtcga cattaagaca ctgggacaac acattgaagt gtattccgta cctaagaaac
      241 aatcataaaa ctcaaagcct tgttaccgag gcttttttat tatatgattt tcagtggcca
      301 gacttattct atctaataca agtaaagcta agtatttaag atttagcaga tgatgaagaa
      361 aagaaaggat ggcctaaata ttttaacaga tttacgaggc taatcatggt ataatatagg
      421 gtgatgaaaa attccaacga ggctgagatg aaattacttt atactgatat tcgaacttct
      481 ttgacagaaa ttctaacaag agaggcagaa gagctagttg cagctggcaa gcgggtcttc
      541 tacattgccc ccaactctct ttcttttgaa aaggaacgcg ccgtgctgga atgcttgtcc
      601 cagcaggctt ctttttcgat taccgtcacg cgctttgctc aaatggctcg ttatctggtc
      661 ttgaatgatt taccagttaa aactactctt gatgatatcg gtcttgggtt ggccttttac
      721 aaatgccttg ccgaactcga tcccaaggac ttgcgtgttt atggagctat taagcaggat
      781 cctcaattga tccagcagtt aattgagctt taccatgaga tgaccaaatc tcagatgaat
      841 tttttggact tggagaattt aacagatgag gataagaggg cggatttact cttgattttt
      901 gagaaagtaa cagcctatct taatcaaggt cagttagccc agggaagtca gttgtcccat
      961 ttgattgagg ctattgagaa tgacaaggta agtagtgatt ttaatcaaat cgccttggtc
     1021 attgacggct ttactcgttt ttctgctgag gaagagcggg ttgtggactt acttcacggc
     1081 aaaggtgttg agattgttat cggggcttat gctagtaaga aagcctatac cagtcctttt
     1141 agcgagggca atctctacca agccagcgta aaatttctcc atcatctggc ttctaaatac
     1201 caaacgcccg ctcaggactg ttctcaaact catgagaaga tggatagttt tgacaaggcc
     1261 tctcgtttgt tggagtcttc ttatgacttt tcagaactcg ctttggatgt cgatgagaaa
     1321 gaccgtgaaa atttacaaat ctggtcttgt ttgacgcaaa aggaggagtt ggagctagta
     1381 gcccgtagca ttcgtcagaa attacatgag aactcagacc tgagctacaa gcattttcgt
     1441 attctcttgg gggatgtagc ttcttaccag ttatctctca aaaccatttt tgaccagtat
     1501 cagattcctt tttatcttgg tagaagcgaa gccatggctc atcatccctt gactcagttt
     1561 gtcgagtcta ttttagcttt aaaacgttac tgttttcgtc aggaggattt gattaatctt
     1621 cttagaactg acttgtatac tgacctcagt cagtctgata ttgatgcttt tgagcaatat
     1681 atccgctatc ttggtatcaa tggcttgcca gcctttcagc aaatcttcac caaatcccac
     1741 catggaaaat ttaatcttga gcgtttgaat gtcctccgcc tgagaatttt agcacctctt
     1801 gaaaccctct ttgccagccg aaaacaaaag gctgaaaacc tcctacaaaa atggagtgtc
     1861 tttctaaaag aaggagctgt gaccaagcag ttacaagatt tgacaaccac tttggaagct
     1921 gtagaacagg aaagacaagc cgaagtttgg aaggctttct gccatgtttt agaacaattt
     1981 gcgactgttt ttgctggttc acaggttagt ctggaagact tcctagcctt gctccattct
     2041 ggaatgagtt tgtcccaata ccgtaccatt ccagcaacag tggacactgt tctggtgcag
     2101 agttacgatt tgattgcacc attgactgct gactttgtct atgctattgg actaactcag
     2161 gacaatttac caaaaatttc tcaaaacacc agtcttctga cagatgaaga aaggcaaaat
     2221 ctaaaccaag cgaccgaaga aggcgttcaa ttactgattg ccagcagtga aaatctcaag
     2281 aaaaatcgct acactatgct ttccttagtc aattctgctc gtaagcagtt gttcttgtcg
     2341 gctccaagcc tttttaacga aagtgaaagt aaggaatctg cctatcttca agagttgatc
     2401 cattttggat ttaggcggag agagaagagg atgaatcaca aaggactgtc taaggaggat
     2461 atggggtcct atcacagtct tttgtctagt ctggttgcct atcaccagca gggtgagatg
     2521 agcgatactg agcaagattt gacttttgtc aaggttctgt cgcgtgtcat aggtaaaaaa
     2581 ctagatcagc aaggtctgga aaatccagcc atcccaatca gtccaagcag caagacctta
     2641 gccaaggaca ccttgcaagc tctctatcct gccaaacagg agttttacct gtctacgtcg
     2701 ggtttgacag agttttatcg caatgaatac agttatttcc tacgctacgt tttaggcttg
     2761 caggaggaat tacgtttgcg tcctgatgcc cgtagtcacg ggaatttctt gcatcgtatc
     2821 tttgaacgcg ccttgcagtt gcctaatgaa gattcctttg accaacgtct agaacaagct
     2881 attcaagaaa ccagtcaaga acgcgaattt gaagctattt atcaagaaag tttggaagcc
     2941 cagtttacca aggaagtttt gcttgatgtt gcacggacaa ctggacatat tctccgacac
     3001 aatccagcca tcgaaacaat caaagaagaa gcaaattttg gtggaaaaga ccaagccttt
     3061 attcaattag acaatggacg cagtgtcttt gtacgaggca aggtggaccg gattgaccgt
     3121 ttgaaagcta atggagcgat aggagtagta gactacaaat ccagtctgac tcagttccag
     3181 tttcctcatt tctttaatgg gctcaattct cagttaccaa cctatcttgc tgccctaaaa
     3241 agagaagggg agcagaactt tttcggcgcc atgtacttgg aaatggctga acctgtccaa
     3301 tctctgatgg cggtaaaaag tctggcagga gcagtggtag aagccagcaa atctatgaaa
     3361 taccaagggc tcttcttgga aaaagaaagc agttatttag gcgaatttta taacaaaaac
     3421 aaggcgaatc aactgacaga tgaggaattt cagctcctac tggactacaa tgcctatctt
     3481 tacaagaaag ctgctgagaa gattttagca ggccggttcg ccatcaatcc ttatactgaa
     3541 aatggcagaa gcattgcccc atacgtccag caacatcagg ctattacagg ctttgaagcc
     3601 aattaccatc tgggccaagc ccgtttccta gaaaagttgg acctagctga tggcaagcgt
     3661 ctggtcggag aaaaactcaa gcaagcttgg cttgaaaaaa taagagagga gttgaatcga
     3721 tgaagcttat tcccttttta agtgaggagg agattcaaaa actgcaagaa gcagaagcaa
     3781 attcgagcaa ggaacagaag aaaactgccg agcaaatcga agctatctac acttctggcc
     3841 agaatatcct ggtctcagca tcggctggtt ctggaaagac ctttgtcatg gcagagcgca
     3901 ttctggacca attggcgcgt ggtgtcgaaa tttctcaact ctttatctca acctttaccg
     3961 tcaaggctgc aaatgaactt aaagaacgtt tagagaaaaa aatcagcaag aaaatccaag
     4021 aaacagatga tgtcgacctc aaacaacact tgggacgcca gttggcagac ctaccaaacg
     4081 ctgccatcgg aaccatggac tctttcacac aaaaattcct tggcaaacat ggttatctgc
     4141 ttgatattgc acctaatttc cgtattttac aaaaccaaag cgagcaactt cttctcgaaa
     4201 acgaagtctt tcatgaggtc tttgaagcgc attaccaagg taaacagaaa gagaccttta
     4261 gtcatttgct gaaaaacttt gctgggcgtg gcaaggacga acggggtctg cgccagcagg
     4321 tctataaaat ctatgacttc ctccaatcca ccagtaatcc tcaaaagtgg ctgagtgaat
     4381 ctttcctcaa aggctttgag aaagctgatt ttaccagtga aaaagaaaaa ctgactgagc
     4441 aaatcaaaca agccctttgg gatttggaaa gctttttccg ttaccatctg gataacgatg
     4501 ccaaggagtt tgcaaaggct gcctatttag aaaatgttca gttaattctg gatgaaattg
     4561 gctccctaaa tcaggagtcc gatagtcagg cttatcaggc agtgcttgcg cgtgttgtcg
     4621 ccatctctaa ggagaaaaac ggtcgagctc tgactaatgc cagtcgtaag gctgatttga
     4681 agcccctggc tgatgcctac aacgaagaga gaaagaccca gtttgctaaa ctaggacaat
     4741 tatcagacca gataaccatt ctcgactatc aagaacgtta tcatcaagac acatgggaac
     4801 tagctaaaac cttccaaacc tttatgagtc attttgtgga ggtttatcgt cagcgcaaac
     4861 gccaggaaaa tgcctttgaa ttcgctgata tcagccatta caccattgag attttagaga
     4921 atttcccaca agttcgtgag tcttatcagg agcgcttcca tgaagtcatg gtcgatgagt
     4981 atcaggatac caaccatatt caagaacgga tgctggaatt gttgtctaat ggccacaatc
     5041 gctttatggt gggagatatc aagcaatcca tctatcgttt ccgtcaggca gacccgcaga
     5101 ttttcaatga gaaattccaa cgctatgcgc aaaatcccca agaaggcaag ctcattctcc
     5161 tcaaggaaaa tttccgtagt agttcagaag tgctgtcagc aaccaatgat gtctttgaac
     5221 gtctcatgga ccaagaggtc ggcgaaatca actatgataa caagcaccag cttgtttttg
     5281 ccaataccaa actgactccc aatccagaca acaaggcaga atttctcctc tacgacaagg
     5341 acgatacagg tgaggaagaa gagagtcaaa cagaaacgaa actaacaggc gaaatgcgct
     5401 tagttatcaa ggagattctg aaacttcatc aagaaaaagg tgttgccttt aaggaaattg
     5461 cccttctgac ctccagccgc agtcgtaatg accagattct cctcgccctg tctgagtacg
     5521 gaattcctgt caaaactgac ggagagcaaa acaattatct ccaatcccta gaagtgcaag
     5581 tcatgctaga cactcttcgt gtcattcaca atcccctgca agactacgcc ttggttgccc
     5641 ttatgaagtc tccaatgttt ggttttgatg aggatgagct agcacgtttg tcccttcaga
     5701 aagcagagga taaagtccac gaaaatctct atgagaaact ggtcaatgca caaaaaatgg
     5761 caagtagtca aaaaggcttg attcacacag ctctagctga aaaactaaag caattcatgg
     5821 atatcctagc ttcttggcgc ttgtatgcca aaacccattc tctctatgac ttgatttgga
     5881 agatttacaa cgaccgtttt tattatgact atgttggggc tttgccgaat ggtcctgcta
     5941 ggcaggccaa tctctatgcc ctagcactgc gtgctgatca atttgaaaag agcaatttca
     6001 aaggtttgtc gcgttttatt cgtatgattg accaagtctt agaagcccag cacgatttgg
     6061 caagcgtagc cgtcgcaccg ccaaaagatg cagtagagct catgaccatc cacaagagta
     6121 aagggctgga gtttccttac atctttatcc tcaatatgga tcaagatttc aacaagcaag
     6181 actctatgtc agaagtcatt ctcagtcgtc agaatggtct tggtgtcaaa tatattgcca
     6241 agatggagac aggggcagta gaagaccact atcctaaaac catcaaactc tccattccta
     6301 gtctgaccta taggcagaac gaagaggaat tacagctagc aagctattct gagcagatgc
     6361 gtttgctgta tgttgctatg acgcgggctg agaaaaagct ctatcttgtc ggcaagggtt
     6421 ctcgtgaaaa gctggaatcc aaggaatacc cagcagccaa aaatgggaaa ctaaatagca
     6481 atactagact gcaagcacgg aatttccaag attggctttg ggctatcagt aaagtgttta
     6541 ctaaggacaa gctcaacttt agttatcgtt ttattggcga agatcagttg accagagaag
     6601 ctatcggaga gttggaaacc aagagtcctc tccaagatag ctcccaagca gacaatcgtc
     6661 agtcagatac catcaaagaa gctctggaaa tgctgaagga ggtggaagtt tataatactc
     6721 ttcaccgcgc agctattgaa cttcctagtg ttcaaacccc aagtcaaatc aagaaattct
     6781 acgaaccagt tatggatatg gaaggtgtcg agattgctgg tcaaggtcag tcagtaggca
     6841 agaaaatcag cttcgatttg ccagattttt caaccaaaga aaaggtaact ggagctgaga
     6901 ttggtagtgc tactcacgaa ctcatgcaga gaattgacct cagccagcaa ctaaccctta
     6961 ctagcctaac agaaacactc aaacaagttc aaactagcca agctgtcaga gacaagatca
     7021 atcttgataa aattcttgct ttctttgaca cagcactcgg tcaggaaatt cttgctaata
     7081 ccgaccatct ctatcgcgag caacctttct ccatgctcaa acgagaccaa aagagtcagg
     7141 aagactttgt tgtccgtggt atccttgatg gctatctgct ttacgaaaac aaaattgttc
     7201 tgttcgacta caagacagac cgctatgatg aaccaagtca actcgtagac cgctatcgtg
     7261 gtcagttagc tctatacgaa gaggctttat cacgagccta ttcgattgaa aatattgaaa
     7321 aatacttgat tttactcggt aaagacgagg ttcaagttgt aaaagtataa cttatactct
     7381 tcgaaaatct cttcaaacca cgtcagcttc gccttgctgt atatatggtt actgacttcg
     7441 tcagttctat ccacaacctc aaaacagtgt tttgagctga ctgcggctag ctttctagtt
     7501 tgctctttga tttttattga gtattagaaa ggagacctca tgacacttcc agttagaaaa
     7561 tccctgcacg atgcagtttt acaggcttcg aaagcggata cttgggaaca agctaccaag
     7621 gaatggaatg aagtttcctt gatttttaac ggtatcggcc gtagcaattg tgtctgtgga
     7681 aatgccatca aatacgctta tgaactcttt aacggtgtca caggccaacg cctctttcca
     7741 attggtagcg actgtgttcg tcattttcat cgattgtccc ttgaccagca attggaagag
     7801 gaagaaaaac tgctcagaaa ggttgaaaat ctaaccagaa aagctcagaa aaaggaaaaa
     7861 atcaaggtca ataaaagtga ctttgacgag cgacttctaa aatggctctg ggaaaaaggt
     7921 gttttcaaac ccaatcgtgg caatcaattt gcgcctgaga gagactacca gcttttccta
     7981 gaagtctttc agggaggaag ttggaccaag gcggaaccaa agaaaaaggc tcggatggaa
     8041 gaagtccttg aaaagtgtat caaacccttt ttacttggga aatcggatga ccaactctac
     8101 cttgtcaagc taggcaagga gaaaattgac tacgaacaag aactccgtat ccaggcagag
     8161 aaagaacgca agaagaggga taaaatcgcc aagcaatatg cagacaatct ggttctagcc
     8221 atgggacccg cagagcgtgc ttatcaagat tactttggct ttacagagac cctgactcaa
     8281 gaagaacgca agtgggaaaa aattcttttt ggtaaaaata gagcagaacg ggatatcaag
     8341 gccaaacaat accaaaaaga gctggaaaaa gaccaacgaa ttgccagtca ggatccaatt
     8401 gaaagaaaac agaagcagac ttggctcctc aattcctatt ttcgtgagct tcctgaagaa
     8461 aaagctcgat tttctaggct cttattagaa tatcgaaaaa gtggtgaagt acccttttca
     8521 actgaatacc tgtccgatca tctcatcgac tttttctata aaatgaaagc ctttgaattt
     8581 gaaatcgcac cagaacaagt ccgagatttt ctaaaaaaaa gcctgcagga agaccatcgc
     8641 tcatcagcac aaggaagctg gatagaagga attctcctca actgcctcaa accattttta
     8701 gaacgattag tgatatgagt aacacctacc gtgtaaattt catggtaggt gttattgtac
     8761 ctcaaaataa tataaaacaa agtatgaaag cgcatctcaa ttttaagact tttttgtaaa
     8821 ttaagagtat aattaaggta tactgccttt tctatagata atatataata cactaatata
     8881 ataaaggtct ttgtaacata tataaatttt atttcaagga ggaataatgg aaaagtattt
     8941 tggtgaaaaa caagagcgtt tttcatttag aaaattatca gtaggacttg tatctgcaac
     9001 gatttcaagt ttatttttta tgtctgtatt agctagttca tctgtggatg ctcaagaaac
     9061 tgcgggagtt cactataaat atgtggcaga ttcagagcta tcatcagaag aaaagaagca
     9121 gcttgtctat gatattccga catacgtgga gaatgatgat gaaacttatt atcttgttta
     9181 taagttaaat tctcaaaatc aactggcgga attaccaaat actggaagca agaatgagag
     9241 gcaagcccta gttgctggtg ctagcttagc tgctctggga attttaattt ttgctgtttc
     9301 caagaaaaag gttaagaata aaacggtatt acatttagta ttggttgcgg gaataggaaa
     9361 tggtgtctta gtttcagtcc atgctttaga aaatcatctt ttgctaaatt acaatacgga
     9421 ctatgaattg acctctggag aaaaattacc tcttcctaaa gagatttcag gttacactta
     9481 tattggatat atcaaagagg gaaaaacgac ttctgatttt gaagtaagta atcaagaaaa
     9541 atcagcagcc actcctacaa aacaacaaaa ggtggattat aatgttacac caaattttgt
     9601 agaccatcca tcaacagtac aagctattca ggaacaaaca cctgtttctt caactaagcc
     9661 gacagaagtt caagtagttg aaaaaccttt ctctactgaa ttaatcaatc caagaaaaga
     9721 agagaaacaa tcttcagatt ctcaagaaca attagccgaa cataagaatc tagaaacgaa
     9781 gaaagaggag aagatttctc caaaagaaaa gactggggta aatacattaa atccacagga
     9841 tgaagtttta tcaggtcaat tgaacaaacc tgaactctta tatcgtgagg aaactataga
     9901 gacaaaaata gattttcaag aagaaattca agaaaatcct gatttagctg aaggaactgt
     9961 aagagtaaaa caagaaggta aattaggtaa gaaagttgaa atcgtcagaa tattctctgt
    10021 aaacaaggaa gaagtttcgc gagaaattgt ttcaacttca acgactgcgc ctagtccaag
    10081 aatagtcgaa aaaggtacta aaaaaactca agttataaag gaacaacctg agactggtgt
    10141 agaacataag gacgtacagt ctggagctat tgttgaaccc gcaattcagc ctgagttgcc
    10201 cgaagctgta gtaagtgaca aaggcgaacc agaagttcaa cctacattac ccgaagcagt
    10261 tgtaagcgat aaaggcgtac cagaagttca acctgaatta cccgaagcag ttgtaagcga
    10321 taaaggcgta ccagaagttc agcctgaatt acccgaagca gttgtaagtg ataaaggtga
    10381 accagagcag gtagcaccat tgccagaata taaggggaat attgagcaag taaaacctga
    10441 aactccggtt gagaagacca aagaacaggg tccagaaaaa acggaagaag ttccagtaaa
    10501 accaacagaa gaaacaccag taaatccaaa tgaaggtact acagaaggaa cctcaattca
    10561 aggagcagaa aatccagttc aacctgcaga agaatcaaca acgaattcag agaaagtatc
    10621 accagataca tctagcgaaa atactgggga agtatccaat aaacctagtg attcgacaac
    10681 ctcagttgga gaatcaaata aaccagaaca taatgactct aaaaatgaaa attcagaaaa
    10741 aactgtagaa gaagttccgg taaatccaaa tgaaggcaca gtagaaggga cctcaaatca
    10801 agaaacagaa aaaccagttc aacctgcaga agaaacacaa acaaactctg ggaaaatagc
    10861 taacgaaaat actggagaag tatccaataa acctagtgat tcaaaaccac cagttgaaga
    10921 atcaaatcaa ccagaaaaaa acggaactgc aacaaaacca gaaaattcag gtaatacaac
    10981 atcagagaat ggacaaacag aaccagaacc atcaaacgga aattcaactg aggatgtttc
    11041 aaccaaatca aacacatcca attcaaatgg aaacgaagaa attaaacaag aaaatgaact
    11101 agaccccgat aaaaaggtag aagatccaga gaaaacactt gaattaagaa atgtttccga
    11161 cctagagtta tacagtttgt caaatggtac ttataaacaa cacatttcgt tagagcaagt
    11221 tccaagcaat ccaaatagct actttgttaa agtgaaatct tcttcattca aagatgtata
    11281 cctaccagta gcatcaatat cagaggaaag aaaaaatgat aaaatccttt ataaaatcac
    11341 agcaaaagta gagaagcttc agcaggagat agaaagcaga tataaagata attttccctt
    11401 ctatctagct aagaagggaa cagaagaaac aacaaacttt acttccttta gtaatctggt
    11461 caaagctata aaccaaaatc tctctggaac ctatcattta ggagctagcc tgaatgctaa
    11521 cgaagtggag cttagtactg atgataaatc ctatatcaag ggaaccttta ctggtcagtt
    11581 gattggtgaa aaagatggta agcattatgc tatttacaac ttgaaaaagc ctctttttga
    11641 aaacttgagt ggtgctacag tagaaaaact gagtctaaaa aatgttgcta tttcagggaa
    11701 aaatgatatt ggttcactgg caaatgaagc tacgaatggc acaaagatta aacaagttca
    11761 tgttgatggt gttctggctg gagaacgtgg tgtcggtggt ttgttggcta aggcagacca
    11821 atcaagcatc gcagagagca gtttcaaggg aagaattgtc aatacctatg aaacgactga
    11881 ttcctacaat attggcggtc tggtcggtca tttaacagga aaaaatgcgt ctattgctaa
    11941 atccaaagcg acagtaacca tttcgtcaaa caccaatagg tcagatcaga ctgtcggtgg
    12001 tcttgcaggt ctagtagacc gagatgcaca gatccaagat agctatgctg aaggtgatat
    12061 caacaatgtc aagcactttg gtagagtcgc tggagtggca ggcaatttgt gggatcgaac
    12121 ttctggtgat gttaggcatg ctggaagttt gaccaatgtt ctcagcgatg ttaatgtaac
    12181 aaacggaaat gccatcactg gataccacta tacaggaatg aaggtagcta atacatttag
    12241 tagtaaggct aatagagttt tcaatgtcac tttagagaag aatgaggtcg tcagcaaaga
    12301 atccttcgag gaaagaggaa caatgctaga tgcttctcaa attgcaagca aaaaagcaga
    12361 aatcaatctt atcactccac caatagtgga acccctctca acaagcggta agaaagacag
    12421 tgatttttct aagatagccc attatcaagc caaccgtgct ttggtttata agaacattga
    12481 aaaattgtta cctttctata acaaggcgac catcgtgaaa tacggaaacc tggttaagga
    12541 gaacagtatc ttatatcaaa aagaactctt gtctgcagtt atgatgaagg atgaccaagt
    12601 aatcacagat attatttcca acaaacagac tgcaaacaaa ctcttgcttc actacaagga
    12661 ccattcatct gaaaagtttg atctcaggta ccaggctgat tttgccaatt tggcagaata
    12721 tagcattgga gatagtgggc ttctctatac gccaaatcaa ttcttgtatc atcaagattc
    12781 tattattaac caagtgctgc ctgaattgaa tcgagtaaat tatcaatcag atgctgttag
    12841 aaatacactt ggaatttcac cagaagtgaa gctaacggag ttatatcttg aagaacaatt
    12901 taccaaaacg aaagagcatc tagcagagaa cttgaaaaaa cttttatcat ctgatgcagg
    12961 tttagtaaca gacaatgaag ttatgacagg atatataata gataaaatta aacggaataa
    13021 ggaagcctta cttcttggaa tgagttattt agaacgttgg tataacttta gctatggtca
    13081 agtgaatgtc aaagacctag ttatgtatca tccggacttc tttggtaaag gaaatacttc
    13141 accattagat actctgattg agttaggtaa atctggcttt aacaatcttc ttgctaaaaa
    13201 caatgtcgat acttatgcta tcagccttgc cagccatcat ggaacgacag atttgtttag
    13261 cacgttggaa aattaccgaa aagtctttct accagataaa accaataatg actggtttaa
    13321 atcacagact aaggcttaca ttgtcgaaga aaaatccaat atcgaagagg tgaaaacgaa
    13381 gcaaggacta gttggcacta agtattctat tggtgtctat gaccgtatca ctagtgccac
    13441 atggaaatac cgtaatatgg tactacctct acttaccttg ccagaaagat ccgtatttgt
    13501 catttcaacc atatctagtc taggttttgg tgcttatgat cgctatcgta ataaagaaca
    13561 tcaagcaaat ggtgatctta atagctttgt tgaaaagagt gctcacgaaa cagcagagcg
    13621 tcaacgagat cactatgatt attggtatcg tattctagat gaaaaagggc gtgaaaagct
    13681 ttatcgaaat atcttgcttt atgatgccta taaatttgga actaatcata ctgaaggaaa
    13741 ggctacagaa gtagcagatt ttgatagtcc aaatcctgca atgaaacatt tctttggacc
    13801 tgttggaaat aaggttggac ataatggaca tggtgcttat gctacagggg atgcagtata
    13861 ttatatgggg tatcgcatgc tagataagga tggagctatt acgtatactc atgagatgac
    13921 gcataattca gatcaagata tttatcttgg tggttatgga agaagaagtg gacttggacc
    13981 tgagttcttt gctaaaggct tactacaagc accagaccaa ccaagtgatg caacgattac
    14041 tatcaattct atattgaaac attcaaaatc tgatagtaaa gaaggagaac gattacaagt
    14101 acttgatcca actacgagat ttaaagacgc aacagatctt caaaaatacg tccacaatat
    14161 gtttgatgtt gtttatatgt tggaatatct cgaaggtaaa tctattgtta agaaattaaa
    14221 tgtatatcag aaaatagaag ctctcagaaa aatcgagaac caatatctaa cagatcctgc
    14281 tgatggaaat gatgtttatg ctactaatgt tgtgaaaaat ttgactgaag atgaagctaa
    14341 aaaattgacg agctttgata gtttgattga caataacatt ctttcggctc gtgagtataa
    14401 ggctggcact tatgagagaa atggctactt tactataaaa ctctttgcac caatcttttc
    14461 agcattgagc ggtgagaaag gaactccagg tgaccttatg ggacgaagga tagcttttga
    14521 acttctagct gctaaaggat ttaaagatgg tatggtacca tatatttcca accaatacga
    14581 agaagatgct aaacaacaag ggcaaactat caatctttat ggtaaagaac ggggcttggt
    14641 gaccgatgag cttgttttga aaaaggtatt tgatggtaag tataaaactt gggcagaatt
    14701 taagacagct atgtaccaag aacgggtgga tcagtttgga aacttgaagc aggtgacctt
    14761 taaagatccg acaaaaccat ggccaagata tggcacaaag actatcaata atgtggatga
    14821 attgcagaaa ctaatggatg aagctgtttt gcaggatgca aaagaacgta attattatta
    14881 ttggaataac tataatccag aaacggacag tgccgtccat aagttgaaga gagcaatctt
    14941 taaagcctat cttgaccaaa caaatgattt tagaagatca atttttgaga ataaaaaata
    15001 gtgtttacta ttaggaaata aaaagtgaat gtggaggatt agaattgtca ttattaaaaa
    15061 aagataaatt ttccattcgg aaaataaagg gtattgttgg ttcggtattc ttggggagtc
    15121 ttttatttgc accgtcagtt gttggtacat cgacttatca ttacttagat tatagtactt
    15181 tgacacaaac tgaacgtgtt caactcaaac aaggtagacc tgatgaatca aaagagtcat
    15241 atgctttggt ttatgaaaaa gacgcattac caaacacagg aagttctcaa tctattatga
    15301 ctgcattggg tttgttagct atcgggagtc ttattgtgat tatcacaaaa gataaaaaga
    15361 ggaaaaaaat cgctacattt ttgattgtag gggcgacagg tttagttaca ctatcaactg
    15421 cttcagcact taatttgaat gctaacatcc atgagtctgg acgtgatggt gtgttgcaaa
    15481 tttctggtta cagatatgtt gattacttgg agcttgatga tagaactgtt tctccagttg
    15541 agcaacccaa agttgtgacc gacaaaggcg aaccagaagt tcagccagcg ttaccagaag
    15601 ctgttgtaac tggaaaaggg aaaactgaag tacaaccgac attaccagaa gctgttgtga
    15661 ctgaaaaagg ggaaccggaa gtacaaccag tgttaccaga agctgttgtg gctgaaaaag
    15721 gggaaccaga agttcatgag aagcctgact atacgcaacc aataggtgca aaccttgttg
    15781 agcctgaagt tcatgagaaa ctagcataca ctgaacctgt aggtacaaca ggagtagatg
    15841 aaaatggaaa cttgattgag ccacctgtta acgatattcc agagtatact gaaccaatat
    15901 ctacagtttc agaagttgca tcagaaagag aagagttgcc ttctttacat accgatattc
    15961 gtacagagac tattcctaaa accactatag aagaatctga tcctagcaaa tttataggcg
    16021 ataattctgt taaacaagtt ggtgaggatg gcgaacgtca aattgttact agctatgaag
    16081 agttacatgg caaaaaaatc agcgagtcag ttgaaacagt aacaattttg aaagaaatga
    16141 agcctgaaat tattgtaaaa ggtacaaaag aaagaccaaa agaaaaaacg gctcctgttt
    16201 taaccttgac caaagtaaca gaagatgcta tgaatcgttc tgccaactta aattatgagc
    16261 ttgataataa agataatgct gaaatatcaa gtattgtagc tgaaattaaa gatggtgata
    16321 cagtagttaa aagggttgat ttatctaaag aaaaattaac tgacgctgta caaaatttgg
    16381 atttgtttaa agattataag attgcaacaa caatgattta tgatcgtggt caaggttctg
    16441 aaacgtctaa actggatgaa agacctctgc gtttggagtt gaaaaaggtc gaaattaaaa
    16501 atatcgcatc tactaattta gtgaaggtaa atgatgatgg tactgaaaca cctagtgatt
    16561 ttatgaatga aaaaccttca gaagaagatg ttaaaaaaat gtacttaaaa atcactagtc
    16621 gcgataataa ggtaactcgt ttaactgtag actctattga agaagtgact gaagaaggtc
    16681 aaaaacttta caaaataact gctgaagcac aagatttgat tcaacacaca gacccaacga
    16741 aggttcgtaa taagtatgtt tattatatag aaaaacccca tcctaaagaa gataatgtct
    16801 actataactt taaagattta gtagatgcta tgaatactga taaaaatggt acatttaaac
    16861 ttggtgcaga tttgaatgcc actggtgttc caacacctaa gaaatggtat gttgacggcg
    16921 actttagagg tacattgaag agtgtagagg ggaaacatta tactatccac aacacggagc
    16981 gtccgttatt ccagaatatt attggtggta cagtaaccaa agtaaatctg ggaaatgtaa
    17041 atatcaatat gccatgggca gaccgcatcg caccgattgc tgacactatt aaaggtggcg
    17101 ctaaaattga agatgtcaaa gtgactggta acgtattagg tagaaactgg gtatctggat
    17161 ttattgataa gattgacaac caaggtacac tcagaaatgt agcctttatc ggaaatgtga
    17221 catctgtagg tgatggtggt caattcttga ccggtatcgt tggtgagaac tggaaaggac
    17281 tagtcgaacg tgcgtatgtt gacgcaaatc ttattggcaa gaaagccaag gctgctggta
    17341 ttgcttattg gacacaaaac agtggtgaca atcataaagt tggtgtcgaa ggtgcagtca
    17401 agaaaggaat tgtgaagggt accattcagg tagaaagtcc tgttgaagtc ggcggtgctg
    17461 ttggacgttt gagtcatcat ggttatatcg gggaagtcgt atctatgatg aaagttaaga
    17521 agggtgaaat tttttatggt tctagtgata tgaatgatga cccatattgg gtggcgaata
    17581 atgtacgagg aaattatgta gttaatggtg tgagtgaagg tacgatatct tatgctcgtg
    17641 ctaaagaaca ccatcgtatc aaaccaattt cacagtcaga agcagatact aaaattatga
    17701 tgttaggtat tacagcacaa gattttgcta tcaacgaacc tgtggtcaat cgcttaaacc
    17761 gtttaaccag aaaagaagat gaatataagt caacccaaga ctataaagta gatcgagatc
    17821 tggcttatcg taatattgag aaacttcaac cattttataa caaagaatgg attgtcaacc
    17881 aaggtaacaa acttgcagaa gattcaaact tagctaagaa agaagtcctt tctgttacgg
    17941 gtatgaagga tggacagttt gtaactgact tatcagatat tgataagatt atggttcact
    18001 atgctgatgg tactaaagaa gaaatggacg tcactaagaa tgctgattct aaagtgaaac
    18061 aagttcgtga atataccatc gctggacaaa acgttgttta tacaccaaat atggttgaga
    18121 aagaccgtaa ccaattgatt caagatatca aagataagtt ggcgtcagtt caattgattt
    18181 ctcctgaagt acgtgctttg atggatgcac gtaagaaacc agaagaaaat actgatgaac
    18241 gtaagaatgg ttatattaaa gacctttact tagaagaaag ctttgctgaa acgaaagcta
    18301 atcttgataa attggttaaa tccttagttg aaaatgcaga tcatcaatta aatagtgacg
    18361 aagcggctat gaaagcactt gttaagaagg tggatgaaaa taaagctaaa atcatgatgg
    18421 ctctgactta tctcaatcgt tactatgata tcaagtatgg ggatatgact atcaagaact
    18481 tgatgatgtt taaacctgat ttctatggta aatcagttga ccttcttgat ttcttgattc
    18541 gaattggatc aagtgagaga aatatcaaag gtgacagaac tttggatgct tatcgtgata
    18601 tgattggtgg aactattggt aagtctgaat tacatggatt cttagattac aatatgcgtc
    18661 tcttcactaa cgatactgat ttaaatgatt ggttcatcca tgcagctaag aatgtatatg
    18721 tatcagaacc tcaaacaacg aacccagatt ttgttaataa acgacatcgt gcatttgatg
    18781 gtttgaacaa cggtgttcat aatcgtatga ttctacctct attaactctt aagaatgcac
    18841 atatgttctt gatttcaact tacaatacaa tggcttatag ttcttttgag aaatatggta
    18901 agtatacaga agaagctaga aatgaattca aaaaagaaat tgataaggtt gcacatgctc
    18961 aacaaacata cttagacttc tggtcacgtt tagcattgcc aagcgtacgt gaccaattac
    19021 tcaagagtga gaatagggta ccaactcctg tgtgggataa ccaaaactat agtggtatta
    19081 aaggaataaa ccgtatgggt tatgatgaga agaaagtacc aattgcgcca attcgtgagt
    19141 tatatggtcc aacttggaaa ttccataata ccaactggaa tatgggagct atggcatcta
    19201 ttttcccaaa tcctaataac aatgaccaag tttatttcat gggaacaaat atgattagtc
    19261 cgtttggtat ttcagccttt actcatgaaa ctacacacgt taatgataga atgctttact
    19321 tcggtggtca tagacaccgt caaggtacag acgtcgaagc ctatgctcaa ggtatgctac
    19381 aaactccgtc aagtattggt caccaaggtg aatatggtgc tttaggtttg aacatggctt
    19441 atcatcgtga aaatgatggt gaccaatggt ataactatga ccctgataag cttcaaactc
    19501 gtgaagatat cgatcgatat atgaaaaact ataatgaagc actgatgatg ctagatcatg
    19561 tagaagcaga cgccgtactt ccacaattga atggtgataa tagcaagtgg ttcaagaaaa
    19621 ttgatagaga aatgcgcaga aatcttgggg atggtttgaa taacttagta gcaccgcacc
    19681 aatgggacaa cgttcgtgac ttaaatcaag aagagagttc taagaaatta tcaagtatta
    19741 acgatttgat tgataataat ttcatgacca aacacggaaa tccaggtaac ggacgttata
    19801 gaccagagga ttttagacca aactcagctt acgtaaatgt caatatgatg gcaggaattt
    19861 acggtgggaa tacgagtcaa ggtgctcctg gttcattatc gttcaaacat aatgccttcc
    19921 gtatgtgggg ttattatgga tatgacaaag gtttcactag ttatgtatct agcaaatatc
    19981 aaggtgaagc tgataaacaa aaccagggta gattaggtga tgatttcatt atcaaaaaag
    20041 tttcaaacaa ccaattctca aatcttgaag attggaagaa atattggtat catgatgtga
    20101 aatccagagc tgaaaaagga ttcacagaga ttacaattga tggacaaacc attcacaact
    20161 ataatgaact gaaagactta ttcgacaaag ctgtcacaga agacctcaag aaagctggaa
    20221 actactcaaa tactgagaat ttgaaatcca aagtcttcaa agctcttctt aaaaacacag
    20281 acggtttctt taatccattg ttcaaaaaag acat
//
LOCUS       DAVHKZ010000037        18967 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000037 DAVHKZ010000000
VERSION     DAVHKZ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18967
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.037"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(125..487)
                     /locus_tag="VVO74_001691"
     CDS             complement(125..487)
                     /locus_tag="VVO74_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695685.1"
                     /translation="MPKTKTLAKLADVILWSFDFANDHAHAFFMDNVEWSHADSYFFS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(841..2721)
                     /locus_tag="VVO74_001692"
     CDS             complement(841..2721)
                     /locus_tag="VVO74_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU5695686.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVTIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RHAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2715..3584)
                     /locus_tag="VVO74_001693"
     CDS             complement(2715..3584)
                     /locus_tag="VVO74_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU5695687.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILYKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQTCTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3668..6313)
                     /locus_tag="VVO74_001694"
     CDS             complement(3668..6313)
                     /locus_tag="VVO74_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU5695688.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKVLHPTEGYKKMAALILPSYRVEDL
                     DGHPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(6404..7684)
                     /locus_tag="VVO74_001695"
     CDS             complement(6404..7684)
                     /locus_tag="VVO74_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEU5695689.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEKNWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETGQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFVELDLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7855..9939
                     /locus_tag="VVO74_001696"
     CDS             7855..9939
                     /locus_tag="VVO74_001696"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU5695690.1"
                     /translation="MKPLLETIDTRLGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTGQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKASAQADWENLLHRFDVIETGEANRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLKTASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIANCAKKLKNIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            complement(9979..11658)
                     /locus_tag="VVO74_001697"
     CDS             complement(9979..11658)
                     /locus_tag="VVO74_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU5695691.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAYG
                     NGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGNCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKT
                     PRLSQTVAVQGLAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12414..13643
                     /gene="arcA"
                     /locus_tag="VVO74_001698"
     CDS             12414..13643
                     /gene="arcA"
                     /locus_tag="VVO74_001698"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEU5695692.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13701..14717
                     /gene="argF"
                     /locus_tag="VVO74_001699"
     CDS             13701..14717
                     /gene="argF"
                     /locus_tag="VVO74_001699"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEU5695693.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14882..15829
                     /gene="arcC"
                     /locus_tag="VVO74_001700"
     CDS             14882..15829
                     /gene="arcC"
                     /locus_tag="VVO74_001700"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEU5695694.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            16038..17549
                     /locus_tag="VVO74_001701"
     CDS             16038..17549
                     /locus_tag="VVO74_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEU5695695.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17571..18902
                     /locus_tag="VVO74_001702"
     CDS             17571..18902
                     /locus_tag="VVO74_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEU5695696.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLTDKE
                     ELVELLTRCAQNYQLRYEEFDYLASLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
BASE COUNT         5335 a         4306 c         3905 g         5421 t
ORIGIN      
        1 aaatcatcgt aaacgcttcg gattacgaat gaatttgagt gctggtatta tcaatcatga
       61 actaggattc tagttttgca ggaagtctat tgaaatacta agcctacaca gactgatttc
      121 aattttacca ttcttcatag tcaaaaccat cataatctgg atattgttct ggcgacgttc
      181 caaccgaacg tacgagataa gcttcttcgt cctctgtctc gatttctctc agcacttggc
      241 attcaaaacg ccattcatca ccgaagtcga aaataaactt aaatttttgt ttgacactta
      301 ggctatccag atagacattt tctgtgtaac gttcttcaac atcgtcacta acaaagctaa
      361 aaaagtaaga atctgcatga ctccactcaa cattatccat gaaaaatgcg tgagcatgat
      421 catttgcaaa atcaaaactc cataaaatca catctgctag tttcgctaac gtttttgttt
      481 ttggaatcta tatatgtcgg tagcaacctt ttttaaattt gacggaaatg acccaagctt
      541 ctatttcttg ttttactaat tttaagtgta gcataatacc tccaattgct catcgataga
      601 attgctctta ggaaacattc actttctgct attttatcat aagtttgtct aactgtagca
      661 tttgaaacca gataattctt ctgtttcacg cgaaacaccc tgcgccaagc aaggtgttct
      721 tgtttttata ctcaatgaaa atcaaagagc aaactaggaa gctagctgca ggctgctcaa
      781 aacactgttt tgaggttgta gatggaagct gacgtggttt gaagagattt tcgaagagta
      841 ttaagtcgta taaatcgtcg acgctgtcgc aatggtatgc cactggttag ctgtagttgc
      901 tgcgaagtcc ttgtctgcgt agaagtcagt aaatggtagg atttcaactt ccagctcgtc
      961 gatgcggtca agctgaccag ccagataaac ctcgatacgg ctttctgctc gtttgatgcg
     1021 ttgcaagagt ccgcccatac ggatgtcaac tgtatccaaa ccaaagacct tgttttcttt
     1081 cagccattgg tggctaaaga gggcatggaa gtcttcaatt tggcttctaa gttctggtaa
     1141 ttcttgtctg gcgatttgtt gtaaactttc tttatcatcc gcttggtagg catgacgaat
     1201 gcgtcgtccc acatctactt tgctacttaa aatagcattc aactgggcct gagtttcaaa
     1261 gagataagca tagtttccag ctttttcttt aatgttagca agcgtctcag cagcctgagc
     1321 gaagtgcggt ttgtcctgtt caggtgtcat gtgttgatca agaatcggac aaagaatatc
     1381 ctgataaaaa acatagcggt tgggattgat accgctgaga ttgcctggta ggtctggtaa
     1441 gaggttggca agatcaatct gcataaaatc ctcaaccgtt agaccagtat tggtcttgaa
     1501 gtgcgcagac aaactatcta ggtcattgcg atagctgagt tctgcccaga tttgcaagct
     1561 tggtaggata gagaactggg cagtttcacc accattgtct ccccaaccag ttacgatgac
     1621 ttctttaatc tgattggcac ggcaggcttt attagcctcg atagtcacta gacggctaaa
     1681 atggttgtga ggtgtaaagc caatccactt ccaagctccc cctgcaaatg caaggtcatg
     1741 gctaatcttg tgatgattgc ggaaattacg gttgtatttt tcctcgctat cctgataata
     1801 atcccagtaa accagagtca cacggtcttt gagacggtct aggtagacac gagtttcctc
     1861 tggaatttcc acatcacggt cgtactggcc atccgctgac atgagtttga agaacatatc
     1921 actccacatc tggcagtgga aaccatattt gtcagcaata tccagcacgc gctccaagtg
     1981 ttggcacatg aggagactac gatccacaac accgttcaaa atcaggtagc gtcccaaacc
     2041 aaccaagtgg gcttcgtcca tcccgatatt gaccttgcga gtcttcagtt tagacaacgt
     2101 ggcaaacatg ccatcaatca ggtcataaac cttttcttcg ccaatgagaa gaatgtcctc
     2161 tacatcacgg agctcctgga cttccttgac accccatttg acaaaggccg acaagtgggc
     2221 caaggtctgg atgcatggta caaaggtcat gtcaaactgt tgggcatagg cttcgatttc
     2281 ctgcaactcc tctgctgaat aagctccacg gaaatagcca aagtaaggct gtccttcaat
     2341 ctggtaagtg tcttccatgt aaagctcaaa ggttgagtag cccatgagag ccaagacctc
     2401 aatcatctgc ttggcagaag ccacattcag caccgcattt cgagaacagt caaccatgta
     2461 agccaaatct tcgtaagctg cttgttcctc aatctctact ttatcagctt ctgctagaac
     2521 tgttaccaac aaggataagg cacgataaag ttggtgaggt ttgcggtagg tcaattgata
     2581 gtgaccttcc tcaccctcga tagagataga ggcttggtca gactgagtga cagccacttc
     2641 cacatctggt agagaaatat gaccttttaa aacctcaata gcttgcgttt gtttgggact
     2701 aagtcctgta aatcttacca ttgcttttcc tcctgtagcc agttgacaag ggcaccgtag
     2761 agattggcat ctgcgtgata ggtgcaggtc tggataactg gtgcgaccgt gtattcttcg
     2821 taggcatcga caaagtcttc aacagccttc ttaacacctt ggataaaatc tggattttga
     2881 ctgatagagc cacccagact gatgacatct ggatcgatca gatactggat attgagcaag
     2941 ccttgcgtca gattgcggtt catgcgctca atggcttctt gacaaagagc attaccagct
     3001 gcggcctctt ggtaaatctt gcgaccgtcc caatcagtat gaccagattt ttcaatcacg
     3061 tatcgtacca tattcccagt tgatgctagt tgcgaccagt tattaagttt ttcagcaggg
     3121 gcaagggttg tcatgtagcc aaattctcca cccagaccgt ggcgacctcg atgaagtcta
     3181 ccattgataa tcatggctcc gccaatccct gtcccaatca cgacacaggc tgcattttca
     3241 agctctggat gagctagtag ttcactgagt ccaacgcagt tggcatcatt ttctaaatgg
     3301 acaggtagct gataagagct aagcgcctca taccaagaaa agccatggat gtagggcacc
     3361 gcactgaagc catcaatcac acctgtctct tgattgaccg cacctggaac gctcatagca
     3421 atcccactgt aatcctgttc tgacaagcgt tgatctagcc acgctagtaa atcctccaag
     3481 ttttcaggcg ttgaaatact tgtcttatac agtattttcc catcaggagt cagactggca
     3541 aacttaatcc cagtccctcc gatatcaatc gttgcaatgg tcattgtttt taccataaaa
     3601 aggggcgaat cagcagttag ttcttacttt ttcgcccctc ctttcttttg atgtttactt
     3661 tttgaaatta aatttcttct tttttgatga attctgtacg aatctcttgt ggagccaata
     3721 gtcctgaatg aactggatat ggtcgctcaa gtaagtcaag aatggtttgt tgatgttctg
     3781 atatgcgcac attttcttga ctcatattat agtaacggag gacatagcct tcttcatttt
     3841 ccgccacttt aaaggctgtt ggacaaactt gcggtatgct gagaacagaa tggctcaaga
     3901 ggctaccagt cgcaaccacg cttccttcct gtctagcaag ctgaaggctg gtaaacggtg
     3961 tctgcaaggc tttggcacga cgataggctg agaagcgttc ttgggcttgg tggcattcaa
     4021 gtgcaaactc gacttcaaac tcacgcaagc attgtgcttc tggcgttggg aagtagcccc
     4081 agtcacctag ctcacctgat gcacgcaaaa tggtcacggc aatggtgtta tccccaagga
     4141 tttcgtattc attcaatccc ttattggata cagtcacccc tttttcatcg tcatacagac
     4201 tgacaaaagc ttgttggtgt tgaggatttt caggattttc ccatgaagca gctggtttgt
     4261 ttggtcgtgt caccacctca tagatacttt cagaatcatt gcttggacgc gtgttatgag
     4321 tcttgaccaa gagacggata cggtgatcct tggcagtgtt agtaaagcga gtcttgaagc
     4381 ggatttgtgg attgtcaacg aagacagtca actcagtttc cagaggaatg tttgtcaatt
     4441 cttctgaccg tccagcctca cgcttcataa actcgatgat accttgttgc tcttcttcta
     4501 gcttttcatc cgcgctgaca ggcacggtca attcatgttt gagcaagatt ttagcatagc
     4561 aagctgtgtt ttccaagacc tcgtggccct taagttctgc aaagattggc tctgttcctt
     4621 ttggttggaa atagatatac tcgtttccga tgtccccacg gtcttcaaag cggataaagt
     4681 cttcataggc ttcgtgagtt gtcttgtcat agactgtgat gttgtcatcc acactcaccg
     4741 ttacgaatgg tgtatcaatc actccgtttt ggtaaatacc ctcacggtgt tcttgttttc
     4801 cttccagcaa ttggaaggtt gtccaagaaa gcggcgctag gtgaactgga atggtcacgc
     4861 gcacttgacg agcaatacga gcttggcgga acttgtcttt tggtaaatca tactcaaaat
     4921 tagctccgag gtcttcgatt gtagcctcta caggatgacc atccaagtcc tccacacggt
     4981 aacttggcaa gataagagca gccatctttt tgtagccttc tgttgggtgc aataccttga
     5041 aatcacaagt cgccacatca atcactgtgc tgacagtatc gaccttatca tgcaagcctg
     5101 tgttaatgac agtaaagaga tagtcacttt gagccttatc cgtagcaatt ttacccttcc
     5161 actcgttgag caagttactt ttaacaaagt ttcctacttg gttgaccttg gcaaaacgcg
     5221 tttccatctc gcggtgaact tcgtccacgc tacagccaca gatactatca tgtggcgcat
     5281 tctgcaaaag tgttttccaa gcataggtca actggtcctt gtggttgtgt ccaccagtga
     5341 taatagtcaa gggttctacc acttgctcta ggaggttgct attttcttgg aaggcttgtt
     5401 ttaggtaaat gcgggatgaa gaagtgttgg caagtgtgta ccagccatct gtttcctgac
     5461 tggtcaactc gcctgtaaca gttgataagt gttcaggaag cgcaccttct acagcttgaa
     5521 catattcatc aaaagaacta tgaacaaaga ttacatccgg gaagagttca tttgccacac
     5581 gaatggcttc gctcagattt ttctgtacag gctggtggtc acagccgttc atcatcaacc
     5641 attggttggt cgaagcgtag gcacgcacat ctgacaattt ttgtttccag aaggtcaagg
     5701 cctcatcttt gtcaactggg atttcattcc cattactgta ccagttggca aagagaatac
     5761 ctaaaacacg actaccatcc acaccctgcc agtacatttc tgaaaactgg gatgtaaact
     5821 gctcatcttc aaggacttgg ttgtcaaatc caatcggctt cacaccacga ccaaaggccg
     5881 ccacgtgaat gcctgatttt tgaagaattt gaggcgcttg tcccatattt ccaaaggtat
     5941 ctggaaagta gccaatctgg gttgatttac cccatttggc agcttcttgt tgaccaatca
     6001 aggtattgcg gacattggct tcactggaga tcaagtagtc atcctgcaag atgtaaaagg
     6061 gaccaatttt aagtttgccc tcgtcaatgt agcgttggac cttgtcgcga ttttcagggc
     6121 gaatttgtaa gtagtcatca aggacaatag tttgtccatc caagtggaaa ctcttgaact
     6181 cagggtcatt ttcaaagaga tcaaagagat tgtcaaacaa ttccaccaac tgcatacgat
     6241 ggctttcaaa aggcaagtac cactcacggt cccagtgact atgtgagata atatgtacaa
     6301 caacattttc catgaagtaa aacctcattc taaatttaaa ttttaacgtt ttaaatgtaa
     6361 acttgtgatt ctgataagaa tcggttgagc taaagcgagc cccttagcga atatccaagt
     6421 aatccaagac caactcacag aacatcatgt tagcccagga gaaccattca cgagagtaga
     6481 gggtcggatc atctacgtgg aagctttcgt gcatgacacc tgtaccacca tcgcaggcaa
     6541 ccagctgatc cagcaagaat tttttctctg ccttatctct tgttgtcaat ccttggatag
     6601 aaagggcgat tggccagata tagcgataga aggtatgaga acttccgaga ccgctagcgt
     6661 attctccttg gtagaagtat ggattttcag agctcagaat ggtacggcga gtggcttgat
     6721 acacttcatc atcgatcgaa cagtagccca gatagggcgc agctagtaga cttggtacat
     6781 ttggatcatc catgatgctg gcatttccta ggccatctac ttcaaaagcg taaatctttt
     6841 cgcccttgct gttggtggtg taagcgtagt tttcgattcc ttcttggatt tcatcctgaa
     6901 gacgcttggc atcagcaata acactctggc tatcagctag gtctaattcg acaaagattt
     6961 cttgcacata acccaagact actacggcaa acatattaga cggaatcaag taactatact
     7021 gacagcaatc gtcactcgga cgaaaagctg accaagtcat acctgtcact gcaaagtcag
     7081 gtccaaagcc atcatttacc aaggtgtctt ccttacggtc cgtatctcgg acaaaacgat
     7141 aaggagagtt cttgtggtct tgttcaactg tccatagatg gagaatttcc ttagtcgctg
     7201 cgacaaaagt ctcatcaaac tgaccagtct cgccagtctc tttccagagg agataagcca
     7261 actgcaaagg atagcaaagt gaatccacct catacttgcg ctcccagatc cagccgttaa
     7321 ggtctgtgtg gtcagtctcg tggtgccctt tccagttctt ctcaatgttg aaggagttag
     7381 catagggatc cttgagtacc aaggtcatct gacgtttgac caaacctgca atggtctgac
     7441 gcaggagggc atctctttta gctacatgaa ggtagggtct gagttgggct gtcgaatctc
     7501 gaagccacat ggcaggaata tccccagtca agacaaaagt tgaaccatct tctaagattt
     7561 caaccgtatt gtccaaggta tcggtgtagc aacgctcgaa aacatccacc cactctggat
     7621 ggtccttagc ccgctctgct acttcatcta gccattctct aacaatttct ttcgaataaa
     7681 tcatcgtgca attccctctt tcaaacaagt ttcattttca gtatatagct tttgagacag
     7741 aaaatacata cacaaatgat agtcattttt ctacaaaata gttatctttg aaactccttt
     7801 tctaaaggcc ctctttttct gatataatgt agaaaaacag ctaaaggaaa gactatgaaa
     7861 ccactacttg aaaccatcga tacccgcttg ggaactacca acaagcatgc cttttctcgg
     7921 ggaaataccc tgccatacac aggcgtgcct tttgggatga attactttgt gccccagacc
     7981 agtgaccagg atggatcttg gttcttcgat ccgcatctgc ctatctttca ggggattcga
     8041 ttaactcacc agcccagtcc ttggattggg gactactctt ggctccttct gacacctgtc
     8101 acaggtcagc ttgggggaga cagtctcttt caccgccaat cttcctatga tagggataag
     8161 gcctctttcc aacctcatta tctaaagatt ttctccctgc gctatcaaat tgaaacccag
     8221 ctcacaccga cttgctacgg tgcttctatt cgtttgaagc aaaagcaagg caaagccctc
     8281 tccctctatc ttcacgcagc agatgaactg acagtagagc aagtagataa gcgaactctt
     8341 gccctgcgac aagaaggtaa aactgaaacc aacaaaaatt cgctaacgat gttcactgcc
     8401 ctgcaaatga acacggatat tcttgctatc agccaagaag ctggagactg gcgaattgac
     8461 ttagcaagta gtcaaaccga gatgcaacta gccacttctt tcatctctcc ttctcaagct
     8521 ctaatcaatc tacctcaaga agattttgat agctgtaaag caagtgccca agcggattgg
     8581 gaaaatctcc tccatcgttt tgatgttata gagacaggag aggctaaccg aaccttcttt
     8641 gaccactgtc tctacagact cttcctcttc ccacagactt tttatgaggt tgatgagtca
     8701 gggcaagcca tccacatgga tctggctact ggtactgtca agcctggtgt cctctttagc
     8761 aacaatggtt tctgggatac cttccgcacc accttccccc tctttgccct tatcataccg
     8821 gagcactatc aacgcttttt agaaggtttc ctcaatagct accgcgatac tggtttcctt
     8881 ccaaaatggc tggctccaga tgaacggggt atgatgccag gtacactttt agacggtatt
     8941 atcgcagata gcgcctgcaa ggacatggcc cccgacctag aaggagaact cttccaagcc
     9001 atgctcaaaa cagccagcaa agccgaccct ctcggcatca atggccgcca cggactagcc
     9061 caataccaag aactaggtta cctctctacc gaccaccacg aaagtgttag ccatactcta
     9121 gactatgcct atagtgactt ttgtatcgcc aactgtgcca aaaaactaaa aaacatagaa
     9181 atcgctgaaa cctacaaggc tgcttcacaa aattaccgcc agctatttga cgctgagaca
     9241 ggttacatgc gagcacgaga caatcaagga aactttcacc ctgacttctc tccttatagt
     9301 tgggggcgag actacgctga atgctctgcc attcaagcta ctttaggcgt tctccacgac
     9361 atccctggct taatccaact gatgggtgga aaagaaacct ttagcaacta tcttttgaaa
     9421 gcctgtcaag atgctcccct ctttgaaaca acaggctatg gttacgaaat tcacgaaatg
     9481 agcgagatgg ctactgctcc ttttggacaa atagccattt ccaaccagcc tagtttccac
     9541 attccttatc tcttccgcta cagcgattac cctgactaca ctgcccttct tatcaagacg
     9601 ctccgtcaga aagcttttca cccaagttgg gaagcctatc ctggagatga agacaatggt
     9661 agtctctctg cttggtacat ctggtcagct ctcggatttt atccaacctg tccaggaaaa
     9721 ccaagctatg atctcggaat tcctctcttt gaccatctac gagtctacct agctaaagaa
     9781 aataaatggc tagatattca tactgagcaa aaccacagcc attttaactt tgtcaaagaa
     9841 tgccgactgg acaaaacact cgtatcaact attcaacacc aagacctcct aaaagctgaa
     9901 caactaactt tcaccctcag ctggctacca aatcactaat aaccaaaaga acctttgcat
     9961 cgcgcaaagg ttcttctttt atgaaacttg gacttgaagt tgatccacaa gctgaccatc
    10021 caccgttagg ttcagataga aatccaaggt tttatctcct gcgaaataca gggttggtag
    10081 atgcaaatct tttttgcttt cccctgcttg gaattgaagg acttgaatct catcctgata
    10141 ggcgacacca tggacacctg tccccggttg aatcgaaatc ttagcctcta aagaggagct
    10201 actttcacta cgttcaatcc taaaatgaag agtctctccc tttgccacag ctaggctttt
    10261 ttctgcaaat gctagcccct gaacagctac tgtttgtgat aacctcggag ttttatagag
    10321 tgaaatcttg gtcaacaaag gcaaagcctg tgattctgta atgactacac gtatcttctg
    10381 tgcttcaaca actgctcctc gcaagaggcg cttatgacca actgtgaagc ccctgccaaa
    10441 ttcctgccag acaccatcca cctctacttg cacatggaaa gcagaaatac gttggcctaa
    10501 cttcaaatct tctctcaact caattacatc aaaagtttta ggagaaccta agtcgagttc
    10561 taactggatg ggcaagtctg catcgcttgc ccaagagctg gtctcaaggc cgtctgtcaa
    10621 atggcgacaa gcaaagtctg cggaaagagc tggaccagat acctcagctc ccagagccaa
    10681 atcttcttta tagagctcat tgcgataggt cgcaaattca taaagtcgtt caatatcctt
    10741 tgcatcaaag agcccagctt gattcggcgg aatattaagc aagagtggag ttcctcgccc
    10801 tactgagtga aagtagattt cgaccaactc ctcgagagac ttaggatcct gatcctcatg
    10861 gtagaaccag cctggacgga tggaaacatc tgcctctccg attgaaaaaa tcgtgcccga
    10921 gggatccccg tgctgaagat agtccagctc tgcttctgtt cctagtttat caggattcac
    10981 cttttgccac agtggatcac ctgcataccc tcgttcattg ccaatccatc ggatactggt
    11041 gccttctgtt gaaaaaatca agcaattgcc ctgcaggtca cgaatggttt caaaccattt
    11101 ttcaaattca taattaacct tttgcgcgcc ctctcctctg gcaccatcca tccaaacctc
    11161 agcaaatttc cctccatttc cataggcagg atttgataag atttccttca gctgagccag
    11221 ataataggca ttgtagtccg cttctcggtc cacatgatag aggggactat gggcatccca
    11281 cggtgacagg tagaccccca tatccatatc aaactctgtg gcagcttggg atacttcaag
    11341 gagcaagtcg ccctttcctc tcctccaagg actgacctta accgaataat ctgtgtgagc
    11401 tgtcggataa aggacaaagc catcgtggtg cttgaccacc aaaatcaact ttttgaagcc
    11461 cgtttccttg agcacacgaa cccactcacg cgcatccaac tgactcgggt taaagcgctc
    11521 aggatcctcc tgtccagtcc cccattcttg gtcataaaag gtattaggac cgaagtggat
    11581 aaaagctgct agttcatctc ccagataagc tagctgagtc tgacttggta acggtccatg
    11641 cggtttgatt ttcttcatcg ttatatatct ccttctttag caacttctct tgttcacaag
    11701 gttatccaca ggttgtggat aataaaaaat gatctaaccg ccagctcttt ccaactccaa
    11761 ctggtaggct caggattttt ctcctcaata ttccctcttc aaacagctct gtcatatggt
    11821 tctgctaaca cctctcagaa tgctactctc cataattatt ctcaggcttc tttcaggtca
    11881 ttgtgtgaag accattcact ctccagactt ttccacagat tgtgaataag tgattattct
    11941 aaactatcat ctcgtcgact ataacaaaaa ataaaaagag ggtcaataag ataattatct
    12001 cttcctaaat actcagaaaa gattctataa tttgtacaat tgaacaagaa atgcttctcc
    12061 aaaatctatc ttcaaaagaa tgttgcatct ttttatcctt tcacacaaac atttctcttt
    12121 atacagatcc aagtgataac cagatgataa ttggacactt tttggttatt tgtgtatttt
    12181 ttgaaaaatt ttttaaaaaa attttatatc ctctttaata gaagtttatg catttgtatc
    12241 tatgtattct atcctatgtt atgtataata acataaaatt gtgctaaaca tcataattta
    12301 tattattttc cgagaaatta tagccattga cattacctag gaattgcgtt ataacataca
    12361 tgtaagcggt acccaaaatg gtgccaagtc aaaattttta aggaggaaaa tacatgtctt
    12421 cacatccaat tcaggtcttc tcagaaattg ggaaactgaa aaaagttatg ttgcaccgtc
    12481 caggcaagga gttagaaaac ttgttgccgg actatcttga aaggcttctt tttgatgata
    12541 ttcctttctt ggaagatgct caaaaagaac atgatgcatt tgcccaagct cttcgcgatg
    12601 aaggaattga ggttctctac ctagaacaac tcgctgctga atcattgacc tctccagaaa
    12661 tccgcgatca atttatcgag gaatacttag acgaagccaa catccgtgat cgtcaaacca
    12721 aggttgctat tcgtgaattg cttcacggca tcaaggacaa ccaagaattg gttgaaaaaa
    12781 caatggctgg gattcaaaaa gttgaattgc cagaaattcc tgacgaagct aaagatctaa
    12841 ctgacttagt tgaatcagat tatccatttg caattgaccc gatgccaaac ctctatttca
    12901 ctcgcgaccc atttgcaaca attggaaacg ccgtatcgct taaccacatg tttgcagaca
    12961 ctcgtaaccg tgaaacactc tacggtaagt atatcttcaa ataccaccca atctatggcg
    13021 gaaaagtgga tttggtctac aaccgtgaag aagatacgcg tatcgaaggt ggagacgagt
    13081 tagttctttc taaagacgtc cttgcagtag gtatctctca acgtacagac gcagcttcta
    13141 tcgaaaaact tttggtcaac atcttcaaga aaaatgttgg cttcaagaaa gttttggcct
    13201 ttgaatttgc taacaaccgt aaattcatgc acttggatac tgtcttcact atggtagact
    13261 atgacaagtt cactattcac ccagaaatcg aaggcgacct tcacgtttac tcagttactt
    13321 acgaaaacga aaaacttaaa atcgttgaag agaaaggtga cttagctgaa cttcttgctc
    13381 aaaaccttgg tgtagaaaaa gttcatttga ttcgttgcgg tggtggcaat atcgtagcag
    13441 ctgcgcgtga acaatggaac gacggttcta acactttgac catcgcacct ggtgtggtag
    13501 ttgtttatga ccgcaatacc gtgaccaata agattttgga agaatacggg cttcgcttga
    13561 ttaagattcg cggaagtgaa ttggttcggg gccgtggtgg acctcgttgt atgtctatgc
    13621 catttgaacg tgaagaagtg taatcgctgt tcggcattcg tcaatagaaa atgtaaaaaa
    13681 tagaaagagg aaataataaa atgacaaatt cagtattcca aggacgcagc ttcttagcag
    13741 aaaaagactt tacccgtgca gagttagaat accttattgg tctttcagct cacttgaaag
    13801 atttgaaaaa acgcaatatt caacaccact accttgctgg caagaatatc gctctcctat
    13861 ttgaaaaaac atctactcgt actcgtgcag cctttacaac tgcggctatc gaccttggtg
    13921 ctcacccaga atacctcgga gcaaatgata ttcagttggg taaaaaagaa tctactgaag
    13981 atactgctaa agtattggga cgtatgtttg acgggattga attccgcgga ttcagccaac
    14041 gtatggttga agaattggca gaattctcag gcgttccagt atggaacggt ctaactgacg
    14101 aatggcaccc aactcaaatg ctcgctgact acttgactgt tcaagaaaac ttcggtcgct
    14161 tggaaggctt gacattggta tactgtggtg atggacgtaa caacgttgcc aacagcttgc
    14221 tcgtaacagg tgctatcctt ggtgtcaatg ttcacatctt ctcaccaaaa gaactcttcc
    14281 cagaaaaaga aatcgttgaa ttagcagaag gatttgctaa agaaagtggc gcacatgttc
    14341 tcatcactga agatgctgat gaagcagtta aagatgcaga cgttctttac acagacgttt
    14401 gggtatcaat gggtgaagaa gacaaattcg cagaacgtgt agctcttctt aaaccttacc
    14461 aagtcaatat ggacttagtt aaaaaagcag gcaatgaaaa cttgatcttc ctacactgct
    14521 tgccagcatt ccacgatact cacactgttt atggtaaaga cgttgctgaa aaatttggtg
    14581 tagaagaaat ggaagtaaca gacgaagtct tccgcagcaa gtacgctcgc cacttcgatc
    14641 aagcagaaaa ccgtatgcac actatcaaag ctgttatggc tgctacactt ggtaaccttt
    14701 atattcctaa agtataattt tagataataa accgtctacc aacagctatg agggctgcga
    14761 ctaatagctt tagtccggtc ctcttttata taatggtaat ctattatttc ttataaaata
    14821 tgtgaaaaat cattaaattg aaatctaaac gcattctatt gagtgtgata aaggagaatt
    14881 tatggcaaat cgtaaaattg tagtagcttt gggaggaaat gcgattcttt cttctgaccc
    14941 atcagcaaag gctcaacaag aagctttagt tgaaacagct aagcatcttg taaaattgat
    15001 taaaaatgga gatgatctga ttatcactca cggtaatgga cctcaagttg ggaatctctt
    15061 gctccaacat ttggcatcag actctgaaaa gaaccctgcc ttcccactcg actcacttgt
    15121 cgctatgaca gaaggtagca tcggtttctg gttgaaaaat gctttgcaaa atgctctctt
    15181 ggatgaaggc atcgaaaaaa atgttgcctc tgttgtaacg caagttgtcg tagataaaaa
    15241 tgatccagct tttgttaact tgagtaaacc aatcggtcct ttctattcag aagaagaagc
    15301 aaaagcagaa gccgaaaaga gcggagcgac tttcaaggaa gatgctggcc gtggctggcg
    15361 taaggtcgtt gcctcaccaa aacctgttga catcaaagaa attgaaacca tccgtactct
    15421 tttaaataat ggtcaagtcg tcgtagctgc aggtggtggc ggtattcccg tcgtcaaaga
    15481 aaacaatgga catttgactg gtgtcgaagc ggttattgat aaagacttcg cttcccaacg
    15541 tttggcagaa ttggttgatg cagacctctt catcgttttg acaggtgtag attatgtatt
    15601 tgttaactac aacaagccaa accaggaaaa attggaacat gtgaatgttg cccagctgga
    15661 agaatatatc aaacaagatc agtttgcacc aggtagcatg cttccaaaag tagaagcagc
    15721 tatcgctttt gtcaatggtc gtccagaagg aaaagcagtt attacttccc ttgaaaatct
    15781 aggcgccttg attgaatctg aaagcggaac aattattgaa aaaggataag ttgttttact
    15841 aataagatgt attctatttc tagtatcttt atatcaaatt agaaattatt cttgaaaaca
    15901 tgtacaatat ttcaaaagat actagtttta gactttaata tggtaaaaca aatataaata
    15961 gaaagcgttt tcttgaatgt ttatttaaga aagtagttgg ttttttacac tttgttagac
    16021 atcaggagga aaaacaaatg agtgaaaaag ctaaaaaagg gtttaagatg ccttcatctt
    16081 acaccgtatt attgataatc attgctatta tggcagtgct aacttggttt atccctgcgg
    16141 gggcctttat agaaggtatt tacgagactc agcctcaaaa tccacaaggg atttgggatg
    16201 tcctcatggc accgattcgg gctatgctag gtactcatcc agaggaaggt tcgctcatta
    16261 aagaaacgag cgcagcgatt gatgtagcct tcttcatcct tatggttggt ggtttccttg
    16321 gcattgtcaa caaaactggt gctcttgacg tagggattgc ctctatcgtg aagaagtata
    16381 agggccgcga aaaaatgtta attttggtac tgatgccttt gtttgccctc ggtggtacaa
    16441 cttatggtat gggtgaagaa acaatggcct tctatccact ccttgtgcca gttatgatgg
    16501 ccgttggttt tgatagcctg actggtgttg caattatttt gctcggttct caaatcggct
    16561 gtttagcatc tactctgaat ccatttgcga caggtattgc ttcagcgact gcgggagttg
    16621 gtacagggga cggtatcgta cttcgtctga tcttctgggt taccttgact gctcttagta
    16681 cttggtttgt ttaccgttat gcggataaga ttcaaaaaga tccgactaag tcactggttt
    16741 atagtactcg caaagaagat ttgaaacact ttaacgtaga agaatcttca tctgtagaat
    16801 ctacacttag cagcaaacaa aaatcagttc tcttcttatt tgtgttgaca ttcatcttga
    16861 tggtattgag cttcattcca tggacagacc ttggcgttac catttttgat gactttaatg
    16921 cttggttgac tggtcttcca gttattggta atattgtcgg ttcatctact tctgcactag
    16981 gtacttggta cttcccagaa ggcgcaatgc tctttgcctt tatgggtatc ctgattggtg
    17041 ttatttatgg tcttaaagaa gataagatta tctcttcctt catgaatggt gctgctgact
    17101 tgctcagtgt tgccttgatc gtagcgattg ctcgtggtat tcaagttatc atgaacgacg
    17161 gtatgattac cgatacaatc ctcaactggg gtaaagaagg cttgagcggt ctatcttcac
    17221 aagtctttat cgttgtaact tatatcttct atctacctat gtcattcttg atcccatctt
    17281 catctggtct tgccagcgca actatgggta tcatggctcc acttggagaa tttgtaaatg
    17341 tccgtcctag cttgattatc actgcttacc aatctgcttc aggtgtcttg aacttgattg
    17401 caccaacatc tggtattgtg atgggagctc ttgcacttgg acgtatcaac attggtactt
    17461 ggtggaaatt catgggcaaa ctcgtagtcg ctattattgt agtgaccatc gcccttcttc
    17521 tccttggaac cttccttcca ttcctataaa atagtgagtg aggtgattcc atgaaaatag
    17581 atataacaaa tcaagttaaa gatgaatttc ttatatcatt aaaaaccttg atttcctatc
    17641 cttcagtact caatgaagga gaaaatggaa caccttttgg acaagcaatc caagatgtcc
    17701 tagaaaaaac tttagagatt tgtcgagaca taggtttcac tacctatctt gaccctaaag
    17761 gttattacgg atatgcagaa atcggtcagg gagcagagct tctggccatt ctctgtcatt
    17821 tggatgttgt tccatcaggt gatgaagcag attggcagac accgccattt gaagcaacta
    17881 tcaaagacgg ctgggtattc ggacgtggtg tccaagatga taaaggccct tcgctcgcag
    17941 ctctctatgc agtaaaaagc ttgctggacc aaggtattca gttcaaaaag cgcgtacgct
    18001 ttatctttgg taccgatgag gaaaccctct ggcgctgcat ggcacgctac aataccatcg
    18061 aagaacaggc cagcatgggc tttgcacctg actcatcttt tcctctgacc tatgctgaaa
    18121 aagggcttct acaggtcaaa cttcatggcc ctggatcgga tcaactagag cttgaagtag
    18181 gaggcgcctt taacgttgta ccagacaagg ccaactacca aggtcccctc tatgaacagg
    18241 tttgtaacga tctcaaagaa gctggttatg attaccaatc cactgaacaa accgtaacgg
    18301 ttctcggagt gccaaagcat gctaaggatg ctagtcaagg tatcaatgct gtcatccgac
    18361 tagctaccat tcttgctcct ctccaagaac accctgctct cagctttctt gcaacacaag
    18421 caggtcaaga cggcacagga agacaaatct ttggtgatat agcagatgaa ccttctggtc
    18481 acctatcctt taatgtcgca ggtctcatga tcaatcatga acgttctgaa atccgtattg
    18541 acattcggac tcctgtctta actgataagg aagaactagt agagttgctt acaagatgtg
    18601 cacaaaacta ccaactccgc tacgaagagt ttgactatct agcgtctcta tacgtcgcaa
    18661 aagacagtaa actcgttagc acactgatgc aaatctacca agaaaagact ggcgataaca
    18721 gtcctgctat ttcatccggt ggtgccactt ttgctcgcac catgccaaat tgtgtagcct
    18781 tcggcgcctt attcccagga gcgaagcaga cagaacatca ggcaaatgaa tgtgccgttc
    18841 tagaagattt gtaccgtgct atggatattt atgccgaagc cgtctatcga cttgcaactt
    18901 aatcaggcaa ctgtttctac caaaaaaaat cccgcaaaat gaactgcacc ccaaaagtta
    18961 gacagaa
//
LOCUS       DAVHKZ010000038        18462 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000038 DAVHKZ010000000
VERSION     DAVHKZ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18462
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.038"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..193
                     /locus_tag="VVO74_001703"
     CDS             <1..193
                     /locus_tag="VVO74_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5695697.1"
                     /translation="LKPLIAEDKAYNYALSKERSKVENIFAKVKTFKMFSTTYRNHRK
                     RFGLRMNLIAGIINHELGF"
     gene            242..706
                     /locus_tag="VVO74_001704"
     CDS             242..706
                     /locus_tag="VVO74_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEU5695698.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTSLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            863..1288
                     /gene="lacA"
                     /locus_tag="VVO74_001705"
     CDS             863..1288
                     /gene="lacA"
                     /locus_tag="VVO74_001705"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU5695699.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1319..1834
                     /gene="lacB"
                     /locus_tag="VVO74_001706"
     CDS             1319..1834
                     /gene="lacB"
                     /locus_tag="VVO74_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU5695700.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1845..2774
                     /locus_tag="VVO74_001707"
     CDS             1845..2774
                     /locus_tag="VVO74_001707"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU5695701.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2776..3756
                     /gene="lacD"
                     /locus_tag="VVO74_001708"
     CDS             2776..3756
                     /gene="lacD"
                     /locus_tag="VVO74_001708"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU5695702.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQRTATSWKERV"
     gene            4162..4638
                     /locus_tag="VVO74_001709"
     CDS             4162..4638
                     /locus_tag="VVO74_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695703.1"
                     /translation="MNVDGNKFYNVSVSEDIVNAGQILEDYFYVDKFGNINLKGTPEE
                     LAKNIGISVQEASLMYEAVKELPNVYERGPVGFRFNLGPQVRGMGGWAAGAFATGYAG
                     WHLKQFAVNPVTSGFVAVISGAIGWAVKTAVENYWTVAVATVEVPFVNLVYTIDLP"
     gene            5036..5872
                     /locus_tag="VVO74_001710"
     CDS             5036..5872
                     /locus_tag="VVO74_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU5695704.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIIIGKGIAFGKRKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLKGYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            5908..6225
                     /locus_tag="VVO74_001711"
     CDS             5908..6225
                     /locus_tag="VVO74_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU5695705.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6225..7916
                     /locus_tag="VVO74_001712"
     CDS             6225..7916
                     /locus_tag="VVO74_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU5695706.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            8125..9531
                     /gene="lacG"
                     /locus_tag="VVO74_001713"
     CDS             8125..9531
                     /gene="lacG"
                     /locus_tag="VVO74_001713"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU5695707.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTDYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            9574..9831
                     /locus_tag="VVO74_001714"
     CDS             9574..9831
                     /locus_tag="VVO74_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU5695708.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDELEEFKNLFLNFINPEGWDTISFDSDFMPFQQS"
     gene            complement(10110..10871)
                     /locus_tag="VVO74_001715"
     CDS             complement(10110..10871)
                     /locus_tag="VVO74_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU5695709.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(11053..12015)
                     /gene="nrdF"
                     /locus_tag="VVO74_001716"
     CDS             complement(11053..12015)
                     /gene="nrdF"
                     /locus_tag="VVO74_001716"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU5695710.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(12203..14362)
                     /gene="nrdE"
                     /locus_tag="VVO74_001717"
     CDS             complement(12203..14362)
                     /gene="nrdE"
                     /locus_tag="VVO74_001717"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU5695711.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKDLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(14443..14661)
                     /gene="nrdH"
                     /locus_tag="VVO74_001718"
     CDS             complement(14443..14661)
                     /gene="nrdH"
                     /locus_tag="VVO74_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU5695712.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            15012..15275
                     /locus_tag="VVO74_001719"
     CDS             15012..15275
                     /locus_tag="VVO74_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU5695713.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            15281..17014
                     /gene="ptsP"
                     /locus_tag="VVO74_001720"
     CDS             15281..17014
                     /gene="ptsP"
                     /locus_tag="VVO74_001720"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU5695714.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            17268..>18462
                     /locus_tag="VVO74_001721"
     CDS             17268..>18462
                     /locus_tag="VVO74_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU5695715.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSANDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRENLSNLRTYRRQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEERIARIIPLRYRSNHWVPDSRPEEPSPQPAPNPQPAPSNPIDEKLVKE
                     AVRKVG"
BASE COUNT         5787 a         3313 c         3821 g         5541 t
ORIGIN      
        1 acttaagccg ctaatagctg aagataaagc ctataactat gcgctatcta aggagagaag
       61 caaggttgag aacatctttg ccaaagtaaa aacgtttaaa atgttttcaa caacctatcg
      121 aaatcatcgt aaacgcttcg gattacgaat gaatttgatt gctggtatta tcaatcatga
      181 actaggattc tagtttttca ggaagtctaa taaagaaact agcaaggtca ggccttactt
      241 tattggtgga catccaggat ttaattgtcc tctacttgat gatgaagtct atgaagatta
      301 ttatctagag tttgagaaag aagagacttg ctctgttcca cgtcctttcc cagaaacagg
      361 tatgttggat ttccaagata gaagtccatg gctagaggga caaaaagaaa tagatcttag
      421 ttatgatctt ttcagcacag atgcagtgac tttggatgaa ttgcaatctc gaacaattgc
      481 ccttcgttct cttaaacatg ataagggatt gaaagtgcat tttgcagaat ttccaaacct
      541 catcatctgg tcaactttga acaagggacc tttcattacc tttgaaccat ggtctggctt
      601 gtcaacatcc cttgaagaag gagatcattt agaagataag aagaatgttt gtctcttaga
      661 agccaatcag gttgaagaat tagggtttga gatagaagtt ttataaaaaa gtaaaaaata
      721 aataacaaaa acaaacacaa actattgact tcttcaaaca atagtagtat attatgtttg
      781 tgaggactaa ttgactgttt tttaaagata gccaatacac tgctggaatc cagcatagaa
      841 aaaataaaaa ggagtataca atatgtctat tgttatcggt gcagatgctg caggtttgag
      901 attgaaagaa gttgtgaaag acttcttaga aaaagaaaac ttccaccttg tggatgttac
      961 agctgaaggt caagactttg ttgatgtgac tctcgctgtt gctgcagaag taaacaaaga
     1021 agaacaaaac cttggtatcg tgattgatgc ttatggagct ggtccattta tggttgcaac
     1081 taagatcaaa ggaatggttg ctgcagaagt atctgacgaa cgttcagctt atatgactcg
     1141 tggccacaac aactcacgta tgatcactat gggggcacaa cttgttggtg atgaattggc
     1201 taaaaacatc gctaaaggat ttgttaatgg taaatacgac ggtggtcgtc accaaatccg
     1261 ggttgacatg ttgaacaaaa tgggctaatt agattatagt aagaaaggta agttaaaaat
     1321 gagaattgca attggatgtg accacatcgt aactgatgaa aaaatggcgg tttcagaatt
     1381 tttgaaatca aaaggatatg aagtcattga ctttggtaca tatgaccata cacggactca
     1441 ctacccaatc tttggtaaaa aagtagggga agcagtaact agtggtcaag ctgatctcgg
     1501 ggtatgtatc tgtggtactg gtgttggtat caacaacgct gtaaataaag ttccaggtgt
     1561 tcgttctgcc ttggttcgtg atatgacaac agccctttat gctaaagaac aattgaacgc
     1621 taacgttatc ggctttggtg gtaagattac tggtgaattg cttatgtgtg atatcatcga
     1681 agctttcatt catgctgaat acaaaccatc tgaagaaaac aagaaattga ttgcgaaaat
     1741 tgaacacctt gaaagtcaca atgctcaaca aacagacgca aacttcttta cagaattcct
     1801 tgaaaaatgg gatcgcggag aataccacga ctaagaggtg acctatgatt ttaacagtca
     1861 caatgaaccc atccattgat atttcctatc ccttggatga gttgaagatt gatactgtca
     1921 atcgtgtggt ggatgtaacc aaaacggctg gtggtaaggg acttaatgtt acccgagtac
     1981 tttcagaatt tggcgattct gttcttgcta ctggtttagt gggtggcaaa cttggtgagt
     2041 ttttggttga acatatcgat aatcaagtaa agaaagattt cttctcaatt cagggagaaa
     2101 ctcgtaactg tatcgctatt ctccacggag acaaccaaac agaagttctt gaaaaaggtc
     2161 ctgaagtatt ggaacaggaa ggtcaagact ttttggaaca tttcaaaaaa ctcttggagt
     2221 cagttgaagt agtggccatc tcaggtagtc tgccagctgg ccttccagtt gattactatg
     2281 cgagcttggt agaacttgct aatcaagctg gcaagcctgt agtcttggac tgctcaggtg
     2341 cagcacttca ggctgttctt gaatcacccc ataaaccaac agtcatcaaa ccaaataatg
     2401 aagaattgtc tcagcttctt ggaagagaag tttctgagga tttggatgaa ttaaaagaag
     2461 tacttcaaga acctttgttt gcagggattg aatggattat cgtttcactt ggtgccaacg
     2521 gtacttttgc caaacatggt gacactttct acaaggtaga tattcctaga attcaggtgg
     2581 taaatcctgt tggatctgga gactctactg tggcaggaat ttcttcagga cttcttcaca
     2641 aagaatcgga tgcagaatta ctcatcaagg caaatgtcct tggtatgctc aatgctcaag
     2701 aaaaaatgac tggtcatgtc aacatggcca actatcaagc tctatatgat caattaatag
     2761 taaaagaggt ataaaatggc tttaacagaa caaaaacgtg tacgcttaga aaaactttct
     2821 gatgaaaatg gtatcatctc agctcttgca tttgaccaac gtggtgcttt gaaacgcctc
     2881 atggctcaac accaaacaga agaaccaact gtggcccaaa tggaagaact taaagtcttg
     2941 gtagcagatg aattgactaa atacgcttca tctatgcttc ttgaccctga gtatggactt
     3001 ccagcaacta aagctcttga tgaaaaagct ggtcttctcc ttgcttatga aaaaacaggt
     3061 tatgacacaa caagcacaaa acgcttgcca gactgcttgg atgtttggtc tgcaaaacgt
     3121 attaaagaag aaggtgcaga tgcagttaaa ttcttgcttt actatgatgt agatagctca
     3181 gacgaactca atcaagaaaa acaagcctac atcgaacgca tcggttctga gtgtgtggct
     3241 gaagatatcc cattcttcct tgaaatcctt gcttacgatg aaaaaattgc ggatgcaggt
     3301 tctgtagaat acgctaaagt aaaaccacac aaagttatcg gcgctatgaa agtcttttca
     3361 gacccacgct ttaacattga tgttttgaaa gttgaagttc ctgttaacat taaatatgtt
     3421 gaaggcttcg ctgaaggtga agtagtttat acacgtgaag aagcagcagc cttcttcaaa
     3481 gcgcaagatg aagcaacgaa cttgccatac atctacttga gtgctggtgt atcagctaaa
     3541 ctcttccaag atactcttgt atttgctcat gaatcaggtg caaactttaa cggagttctt
     3601 tgtggccgtg ctacatgggc aggatcagtt gaagcttaca tcaaagatgg tgaagcagca
     3661 gctcgcgaat ggcttcgcac aactggattt gaaaacattg acgaactcaa caaagttctt
     3721 caaagaacag caacttcatg gaaagaacgc gtgtaagaaa gtcctcctag tttaggaaca
     3781 tgaatctaaa aaaatttaaa aaaagttgta tgtaaaggtt tacaaaataa cttacttgtg
     3841 ctatacttaa atcacaagtt aatatgaatt agaaagtaac tatatgaagt ataataaaaa
     3901 taggatatag tttattttac gagctaggaa ggaaaaatac ggaaacaata ttgccagaat
     3961 aaactatatt tagatgcaca tttcattcat tgttttataa aaggagaaga taaacggcta
     4021 ctaaaaagag ttttaaagcg ttagttgtag gactaggtat tgtttcaata ttctcatcag
     4081 ccttacctat ggttagtggt tctgtatttg cagatagtgc cctaactaca gtatacagta
     4141 gataaagcaa atgatattgt tttgaatgtt gatgggaata aattttataa tgtttcggtt
     4201 tcagaagata ttgtaaatgc tggtcaaatt ttggaagatt atttttatgt agataaattt
     4261 ggaaatataa atttaaaagg cactcctgaa gagttagcaa aaaatattgg tatttctgta
     4321 caagaagcaa gtttgatgta tgaagctgta aaagagttac ccaacgttta cgaaagaggt
     4381 cctgtaggtt ttcgtttcaa tcttggtcct caagtgaggg ggatgggtgg ctgggctgct
     4441 ggagctttcg ctactggata tgctggatgg catttgaaac aatttgcggt taatcctgtt
     4501 acatctggat ttgttgctgt aataagtggt gcgattggct gggctgtaaa aactgctgta
     4561 gaaaattatt ggacagttgc tgtagctaca gtagaagtgc cgtttgtgaa ccttgtttac
     4621 accatagatt taccttagag gttatttctt tatgaatcat tcttttaaaa aaataactgt
     4681 attttgtttt atagtttctt gtgttctttg tttattagac ttaatgaatt ttaaaaatgt
     4741 agctactttt ttatttttct gtcttcctgt ttttgttttg atttacaaaa ataaataaaa
     4801 acagagcctc tgtttgatga attttagaac atagttaagt tttaaaaaaa gttgtatgta
     4861 aaggtttaca aaacaaccga cttgtgctat acttaaatca caagttaata caaggtgagt
     4921 gttactaagt aatattaggc atgatcacag gtgaattaga aatcagctga ttttctagtt
     4981 catttgtggt cattttttgt actcatatac ctttaagata taaaaggagg ttgacatgta
     5041 tcgaattcta aatccaatga atcacaatgt ctcgcttgtc agaaatgata agggagaaga
     5101 ggtgattata attggtaagg ggattgcatt cggaaaaagg aagggggatt tgattgctga
     5161 aaatcaggtt gagaaaatct ttcggatgaa gaccgaagag tccagagaaa actttatggc
     5221 tcttctcaaa gatgttccgc ttgattttat cacagtgacc tatgaaatca ttgataagct
     5281 atcaaagaaa tatcattatc cgattcaaga gtatctctat gtaaccttga cagatcatat
     5341 ttactgttct tatcaagctc taactcaagg aaggtacaag gatagtaatc tgccggatat
     5401 ttccgctaag tatcctgtcg cttttcaaat cgcaaatgaa gcttttgaaa tttaccgtca
     5461 gaagctagca gatcattttc ctgaggacga gattattcgg attgcttatc atttcatcaa
     5521 tgccgaaggt gaaaatgaag tggaacttgt ggagtcgatt gataagagga aagaaattct
     5581 caggaatgtt gaagaagtgc taaagggtta tgcaattcaa cgaaccaaaa aaaataatca
     5641 tttctatgat cgctttatga ttcatttgaa ttatttcttg gattatttag acagatctag
     5701 agatgataac caatcacttc tggatatgga agatcatatt aaacaatcct atccaaaagc
     5761 cttcgagatt ggttccaaga tctatgatgt gattacgcaa catacgggtc ttgatttgta
     5821 taaaagtgaa cgagtttatc tagttctaca tatccaacgt ttattgtcat aaaaatttat
     5881 ttaaaactat ataaggagaa ttctatcatg aatagagaag aagtaacatt gttaggtttt
     5941 gaaatcgtag cctatgctgg cgatgctcgt tcaaaactat tggaagcctt gaaggctgct
     6001 gaagctggtg attttgaaaa agcggacgct ctggtagagg aagctggtag ctgtattgca
     6061 gaggctcacc acgcgcaaac aagtctattg actaaggaag cttctggtga ggacttagcg
     6121 tatagtgtga ccatgatgca tggccaagac cacttgatga caactatctt gttaaaggat
     6181 ttgatgcacc atttgatcga actctataag agaggagtta aataatgaac aaactaattg
     6241 catttatcga gaaaggaaag cctttctttg agaaactatc tcgtaatatc tatcttcgtg
     6301 ctattcgtga tggtttcatt gcaggtatgc ctgttattct cttctcaagt atctttatct
     6361 tgattgcctt tgtaccaaac tcatggggct ttaaatggtc tgatgaagtt gtagcctttc
     6421 tgatgaaacc ttatagctat tctatgggta ttctggctct cttggtagct ggtacaacag
     6481 ctaagtcatt gactgactca gtaaaccgga gcatggaaaa aaccaatcaa atcaactata
     6541 tgtcaacgct gttagcagcg attgttggtt tgttgatgtt ggcagctgat cctatcgaaa
     6601 gtggtctagc tactggattc ttggggacaa aaggtttgct ttcagccttc cttgctgcct
     6661 tcgttactgt agccatctat aaggtttgtg ttaagaacaa cgtcactatt cgtatgcctg
     6721 acgaagttcc accaaatatc tcacaagtct ttaaagatgt gattccattc actctatcag
     6781 tggtttctct ttatgctctt gatttactag ctcgtcattt tgttggttct agtgtggcag
     6841 aatcaatcgg taaattcttc gcaccactct tctcagcagc agacggatac cttggtatta
     6901 ccattatctt tggtgccttt gccttcttct ggtttgtggg tattcatggt ccatctattg
     6961 ttgaacctgc tatcgcagcg attacctatg caaatgctga agtcaacttg aaccttctcc
     7021 aacaaggtat gcatgctgat aaaatcctta cttcaggaac tcaaatgttt atcgttacta
     7081 tgggaggtac tggtgcgaca ctggttgttc cattcatgtt catgtggtta acaaaatcaa
     7141 aacgtaaccg tgcaatcgga cgtgcttcag tagttccaac tttctttggt gtaaatgaac
     7201 caatcttgtt tggtgcacca cttgtattaa atccaatctt cttcattcca tttatctttg
     7261 ctccaatcgc aaacgtatgg attttcaaat tctttattga aactcttgga atgaactcat
     7321 tcactgctaa tctaccatgg acaactccag ctccactagg tctagttctt ggaactaact
     7381 tccaagtgct atcattcatt cttgctgccc ttctaatcgt ggttgacgtt gtcatttact
     7441 atccattcct taaggtctat gatgaacaaa ttcttgaaga agaacgttca ggtaagtcta
     7501 atgatgaatt gaaagaaaaa gttgctgcaa acttcaacac tgcaaaagcg gatgctattc
     7561 ttgaaaaagc gggtgtagaa gcagcacaaa atacaatcac taaagaaaca aatgtcctcg
     7621 ttctctgtgc aggtggagga acaagtggtc tccttgcaaa tgctttgaat aaggcagcag
     7681 cagaatacaa tgtccctgtg aaagcagcag caggcggcta tggtgctcac cgtgaaatgt
     7741 taccagagtt tgatcttgtt atccttgccc ctcaagttgc ttcaaacttt gaagatatga
     7801 aggcagaaac agataagctc ggtattaaac tagcgaaaac agaaggcgct caatacatca
     7861 aattaactcg tgatggaaaa ggtgctcttg cattcgtaca agcgcaattc gattaaggct
     7921 agagactctg aaatagtctc ctatcgttac ggaaatcgct atggcgaatt tcctattatt
     7981 aattcgtcgg taaaaagata tcgtttttac ctcctcatgt cacaattcgg tgacttggta
     8041 caagaagtga gatggagaag gatggctcac tgactcctct cctctcactt ttactttatt
     8101 taaatcaaga aataggtgaa aaaaatgaca aaaacacttc caaaagactt tatttttggt
     8161 ggcgcaacag ctgcctatca agcagaaggt gctacacata ctgatggtaa aggaccagta
     8221 gcgtgggata aatatcttga agataactac tggtacactg cagaaccagc cagtgatttt
     8281 tacaatcgat atccagttga cctcaagcta gcagaagagt atggtgtcaa tggtattcga
     8341 atttctattg cttggtcacg tattttcccg actgattacg gccaagtaaa tgctaaaggt
     8401 gttgagtttt atcataattt atttgcagag tgtcacaaac gtcatgttga gccttttgta
     8461 actcttcatc actttgacac gccagaagct ctccactcaa atggagactt cttaaaccgt
     8521 gaaaatatcg aacattttgt agactacgct gccttctgtt ttgaagaatt tccagaagta
     8581 aactattgga caacctttaa tgaaattgga ccaatcggtg atggtcaata tttggttggg
     8641 aaattccctc caggtatcca gtacgacctt gccaaagtct ttcaatcaca ccacaatatg
     8701 atggtgtctc atgcacgcgc ggtaaaattg tacaaagaga aaggctataa aggggaaatt
     8761 ggtgttgttc acgccctgcc aactaaatat cctctagatc ctgaaaatcc agcagatgtt
     8821 cgtgcagctg agttggaaga tatcatccac aataaattca tcttagacgc aacttatcta
     8881 ggtcgctatt cagctgaaac catggaaggt gtcaaccata tcttatcagt caatggtggt
     8941 agcttggatc ttcgtgaaga agattttaca gcattagaag ctgcaaaaga cttgaatgat
     9001 ttcctaggaa tcaactacta tatgagtgac tggatggaag cctttgatgg agaaactgaa
     9061 attatccata atggtaaagg tgaaaaagga agctctaagt atcaaatcaa aggtgttggt
     9121 cgtcgtgtag ctcctgacta tgtaccacgc acggattggg attggattat ctaccctcaa
     9181 ggtttgtatg accaaatcat gcgtgtgaag aaagattatc ctaactacaa gaagatttac
     9241 atcactgaaa atggtctcgg ctataaagat gagttcgttg ataacactgt ttacgatgat
     9301 ggtcgtattg attacgtgaa acaacacttg gagatcttgt ctgatgcgat tgcagatgga
     9361 gctaatgtaa aaggttactt catttggtca ttaatggatg tcttctcatg gtcaaacggt
     9421 tatgagaaac gttatggtct cttctacgta gattttgaaa ctcaagaacg ttatcctaag
     9481 aaatcagctc actggtacaa gaaagtagcg gaaactcaga ttatagacta gtagaattag
     9541 tcattagata tagaatttta gtgagtcaaa aagatgttca aagattttat ccaatctatt
     9601 tatgaaaaag tttatattat aaatttcgaa aaatgctctc aaataccgtg tttgacgagt
     9661 gaagaattga aaagtcttgg aaaatggtat gtctcgactg gtaaagaatg gatttgtcat
     9721 tcagatgatg agctggaaga atttaaaaat ctatttttaa attttatcaa tcctgaagga
     9781 tgggatacta tctcctttga ttcagatttt atgccgtttc aacaatcgta accaatttct
     9841 caaaaaagtt aaatcttata tttagtactc tgtaaaactc ttatctaatc acgttgctta
     9901 tactcaatga aaatcaaaga gcaactttaa actaggaagc gagtcgcaga tttctcaatg
     9961 catagctttg aggaattggg caaaaagtct ttgatataga aaaacgcata gtatcaggtg
    10021 ttgaaacacc tgatactatg cgttttattg tgggaagatt tacttttttt cttctgaaat
    10081 tgagttgtta cccaggctct ttcagtttat taaggcttga tgactttaat gtgtttagat
    10141 agcttaaaaa ggattgaatc acttagttta gaatctgaaa caatagtatc aagatttgat
    10201 acattataaa aagtataaaa atcaaactta ttgaacttgc tatgatctgc gagtaaatat
    10261 tttttattag aattatttaa agcgatgcgt tgagcctctc cctcttcctc gctaaaagta
    10321 gctagagctc cgttttgaat accattacag ctaacgaaag ctttagaaaa ttggagatta
    10381 gagagatttt gtagggtcaa tgtaccaaca aaagcacctg taatatcgcg ataatttcca
    10441 cctattaaaa tcaaatctgt taattttcgt tcgcttaaaa tcagaaaaac aggtagactg
    10501 ttggttacga cgcggatatt gtcaataggc aactcacgcg caaaaaactc taatgttgtt
    10561 cctggtccaa tgaaaatagt ttctctttct tctactagac tgcctgcaaa atgggctatt
    10621 tcttgttttt ctgccgtttg gagggcttgt ttttcaatat ttgatcgctc attagtcaaa
    10681 agggagttgg ttcgaagttt ttcagctcca ccatgcacac gaatcagcaa atctttatca
    10741 gctaattcct gtaaatagcg ccttgcagtc atatctgaaa cggctatttc gtccataatc
    10801 tgtttaactg ttatggttcc tttactattt actatctcta aaattttggc taatttttct
    10861 tgtttgagca tattatcacc tcgtttccta ctactatctt accataaaca aactcatcat
    10921 tcaaatacaa aaacaacaaa atgaaacaaa aacaaaaata tcgaagtttg ttttcaaaac
    10981 tttcgatatt tttgttgggt tataactttg atgtttctag tttacttttt gatgattgag
    11041 agtgatggag aattagtcta aaccgtagtt atagtcatcg tcttgcatgg cttcaacttc
    11101 gccaagaagg taaccatttc cgacttgaga gaagaagtca tggttggaag ttcctgttga
    11161 aataccgttc ataacgattg ggttgacatc ttcagctgaa tctgggaaaa gtggatcttg
    11221 tcccatgttc atgagagctt tattggcatt gtagcgaagg aaggttttaa cctcttcagt
    11281 ccaaccaaca ccgtcataaa gactctctgt gtagccttct tcattttcat aaagagtata
    11341 gagtaggtcg tacatccatt ctttgagttt ttcttgctct tcttcaggca attcattgaa
    11401 accaagttgg aatttgtaac caatgtaggt tccgtgaaca gactcgtcac gaataatcaa
    11461 tttaatgatt tctgcaacgt tggcaagttt gttgttaccg agatagtaga ggggagtgaa
    11521 gaaaccagag tagaagagga aggtttcgag gaagacgctg gcaactttct tttcaagtgg
    11581 gctgccgttt aggtagattt cgttgacaat ctcagccttc ttttgtaggt aaggattggt
    11641 attggtccat tcgaaaattt cttcaatctc agccttagta ttcaaggtag aaaagattga
    11701 tgagtaagat ttagcgtgga cagattccat aaattggatg ttattgaaaa cagcttcctc
    11761 atgtggtgta cggatgtctg cgcgaagggc ttgaacccca gtttcagatt gcatagtgtc
    11821 aagaagggtt aaaccaccaa aaacttttcc gaccaagtct ttctctttgt tagatagctt
    11881 tctccagtca tccaagtcgt ttgataaggg aatacgtgta tcgagccaaa attgctccgt
    11941 cagtttttcc caagttgatt tgtcgatgac atcttcgatg gcattccagt taatggcttt
    12001 gtagtaagtt tccatttaaa atctctttct gtgtttagta ttgcgaactc acaattattt
    12061 ctactttacc ataattctat aggagtatcg cacaaaaagt cggaagcccg acttttaaaa
    12121 tgttacataa attatgttat gacatagtag atttgatttt atcagtgctg cttagggaaa
    12181 aatagtgttt ctatgctaga aactaaatca cacagctttc acattggttg gcgccgactt
    12241 ctccaccgtc atctgtaaag gtacggacgt agtagataga cttgattccc ttgttaaagg
    12301 catagttacg aaggatggac aaatcacgtg tcgtttgttt attttccctc ttccattcgt
    12361 aaaggtcttt tggaatgtca ctacgcatga agagggtgag tgaaagtcct tgatccacgt
    12421 gttcagtcgc agcagcgtaa acatcgatga ctttacgcat atccatatcg taggcagaag
    12481 tgtagtaagg aatggtttct gtagacaagc cagcagcagg gtagtagatt ttaccaattt
    12541 tcttctcttg gcgttcttcg atacgttgcg taatcgggtg gatagaagca gaaacgtcgt
    12601 tgatatagct gatagaacca tttggcgcta cagcaaggcg attttggtgg taaagaccat
    12661 cttcttgaac cttgtcgcga agttcagccc aatcagcaac accagggata aagacatttt
    12721 tgaagagttc tttaacacgg tctgatgttg gaacaaattc accagttaca tacttgtcaa
    12781 agtaacttcc gttagcatag tctgattttt caaagttgtg gaaggtaata ccacgttcac
    12841 gcgcaatatt gtttgactct accaaggtcc agtagttcat aagcataaag tagatgcttg
    12901 taaattcaac agactcaggt gaaccatatt caatgagttg ttgggcaagg tagctgtgca
    12961 gtcccatggc accgagacca aaggtgtggg cttggctatt tccatggtca atcgttggta
    13021 cagctacgat atgtgaacta tctgtaacga aagtaagggc acgaaccata gcacggatag
    13081 aacgaccaaa atcaggtgaa gtcatcatgt taaccacgtt ggttgaaccc aggttacatg
    13141 aaacatctgt tcccatttga aggaattctt gagcatcgtt gatcaagctt ggttcttgaa
    13201 cttgaagaat ctcagaacac aagttactca tgataatctt tccatcaaca ggatttgcac
    13261 ggttagccgt atcgatgttg actacataag gatagccaga ctcttgttgc aatttagaga
    13321 tttcagtttc caaatcccgc gccttgattt ttgtcttgcg aatatttgga tttgcgacca
    13381 attcatcgta tttttcagta atgtcgatgt aattgaatgg cacaccgtat tctttttcta
    13441 cagagtaagg gctgaagagg tacatttctt catttttacg agccaattcg tagaatttat
    13501 caggtactac aacaccaagt gatagagtct tgacacgtac tttttcatca gcgttttctt
    13561 tcttagttga aaggaaagcg atgatatctg ggtgaaagac gttgaggtag acaacaccgg
    13621 caccttgacg ttgccccaat tggttggagt aagagaagct gtcttcaaaa agcttcataa
    13681 caggaacgac acctgaagca gctccttcat agcctttgat aggtgcacca gcttcacgaa
    13741 ggttgctgag ggtaattccc acaccaccac caatacgtga aagttgaaga gctgagttga
    13801 tagaacgtcc gatagagttc atatcatccg tcacttggat taggaaacaa gataccaact
    13861 ccccacggcg agcacgtcca gcattcaaga aggaaggagt agcaggttgg tagcgttggt
    13921 ggatgatttc attggcaata tcgattgcaa cagcttcatt cccatcagcg aaataaaggg
    13981 cgttgaagaa gacacggtct tccatatttt caagatagta ttcaccgtca ttagtcttta
    14041 aggcatattg attgtaaaat ttataagctg ccatgaatga cttgaattgg aagttttggt
    14101 ctttgataaa ttgagccaat tcttccaaga actctggacg gtatttcttg ataaaggctg
    14161 tttcgatgta gttgtgttca atgaggtaat tgattttgtc tttgattgaa tcaaaaacca
    14221 tagtgtttgg aactacattt tctttaaaga aagcatccaa ggcttccttg tctttatgaa
    14281 gcatgatttg tccattaaca ggacggttaa tttcgttatt aagacggaag taagtcacgt
    14341 cttcaagatg ttttaatccc ataaaatttc ccttatctaa ttacaaaaga aaggcttcta
    14401 agttagccct aaaagcagtt ttttctggat gatgtactaa gattatgcta attgcttcag
    14461 ttttcctggt tggaaacctg aaaagacttc agttggtgtt tggataacag gagctgcgct
    14521 aaaaccgagc tctttaactt gatcgacgta ctcaggttgc tcatcaagat tgatttcacg
    14581 ataagagaca ttattactgt ccaagaaacg cttggtcatt ttacattgga cacaattgtt
    14641 tttagaataa acggttacca ttgtgtaact cctcttcaaa atttaatact atcttagtat
    14701 atcagaaaat aaaattttgt caatgatttg aactaaatat agtggtgttc ttttgttgtt
    14761 tttatatata aacacaatat atagtgtttg tgttgtgaaa tagcaatgat tatcctataa
    14821 attgtttttg aagaaactat atcctgtgtt ttgttatcta ggatagaaga ttttcagcaa
    14881 gttatctgaa aggaaattga aggaaaatcc agaaaatgct tgaaaaaaat cctagaagat
    14941 ggtataatac taaattgtaa gggttatcac atataactca aaaaaagaaa gaacaaaagg
    15001 agagtcaaac tatggcttct aaagatttcc acgtagtggc agaaacaggt attcacgcac
    15061 gtccagcaac attgttggta caaactgcta gcaaatttgc ttcagatatc actcttgagt
    15121 acaaaggtaa atcagttaac cttaaatcaa ttatgggtgt tatgagtctt ggtgttggcc
    15181 aaggtgctga cgtaactatc tcagctgaag gtgcagatgc agatgacgct atcgctgcaa
    15241 tctcagaaac aatggaaaaa gaaggattgg cataagggaa atgacagaaa tgcttaaagg
    15301 aatcgcagca tctgacggtg ttgcagttgc aaaagcatat ctactcgttc agccggattt
    15361 gtcatttgag actattacag tcgaagatac aaacgcagaa gaagctcgcc ttgatgccgc
    15421 tctacaggca tcacaagacg agctttctgt tattcgcgag aaagcagtag gtacgctcgg
    15481 tgaagaagca gctcaagttt ttgatgctca cttaatggtt cttgctgacc cagaaatgat
    15541 cagccaaatc aaggaaacta tccgtgcgaa gaaagtgaat gcagaagcag gtctgaaaga
    15601 agttacagat atgtttatca ctatctttga aggcatggaa gacaacccat acatgcaaga
    15661 acgcgcagcg gatatccgcg acgtgacaaa acgtgtattg gcaaaccttc ttggtaaaaa
    15721 attgccaaac ccagcttcta tcaatgaaga agtgattgtg attgcgcatg acttgactcc
    15781 ttcagataca gctcaattgg acaaaaactt tgtaaaagct tttgtaacca acattggtgg
    15841 acgtacaagc cactcagcta tcatggcacg tacacttgaa attgctgctg tattaggtac
    15901 aaacaacatc actgaaatcg ttaaagacgg tgacatcctt gctgttaacg ggatcactgg
    15961 agaagtgatt atcaacccaa cagatgaaca agcggcagaa tttaaagcag ctggtgaagc
    16021 ctatgcgaaa caaaaagctg aatgggcact tttgaaagat gctcaaacag tgactgctga
    16081 cggtaaacac ttcgagttgg ctgccaatat tggtactcca aaagacgttg aaggtgttaa
    16141 caacaacggt gcagaagctg ttggacttta ccgtacagag ttcttgtaca tggattctca
    16201 agacttccca actgaagatg agcagtatga agcatacaag gctgttcttg aaggaatgaa
    16261 cggtaaacct gttgtcgttc gtacaatgga tatcggtgga gataaggaac ttccttactt
    16321 cgatatgcct cacgaaatga acccattcct tggattccgt gctcttcgta tctctatctc
    16381 tgagactgga gatgctatgt tccgcacaca aatccgtgct cttcttcgtg cgtctgttca
    16441 cggtcaattg cgtatcatgt tcccaatggt tgcgctcttg aaagaattcc gtgcagcgaa
    16501 agcagtcttt gatgaagaaa aagcaaacct tcttgctgaa ggtgttgcag ttgcggataa
    16561 catccaagtt ggtatcatga tcgagattcc tgcagcagct atgcttgcag accaatttgc
    16621 taaagaagtt gacttcttct caattggtac aaacgacttg atccaatata caatggcagc
    16681 agaccgtatg aacgaacaag tttcatacct ttaccaacca tacaacccat caatcctacg
    16741 cttgattaac aatgtgatca aagcagctca cgctgaaggt aaatgggctg gtatgtgtgg
    16801 tgagatggct ggtgaccaac aagctgttcc acttcttgtc ggaatgggct tggatgagtt
    16861 ctctatgtca gcaacatctg tacttcgtac acgcagcttg atgaagaaac tcgacacagc
    16921 taagatggaa gagtacgcaa accgtgccct tacagaatgc tcaacaatgg aagaagttct
    16981 tgaacttcaa aaagaatacg ttaattttga ttaatcgaaa aatccctgca actcagttac
    17041 agggattttt ttgatatttt aaaaagaatt ttcaagaaaa tctttcttat agaaagtcca
    17101 accttgaaaa agtagtggtc agaacaaaaa atacttaaat ggttcataaa attcttgaca
    17161 agttggagat ttaggagtaa actattaacc agttaagtaa tagagaggag tttctgcaat
    17221 ttagaaatga attgcaacta gaaatatcaa atagaaagag agtttcgatg aaaattaata
    17281 agaaatacct tgttggttct gcggcagctt tgattttaag tgtttgttct tacgagttgg
    17341 gactgtatca agctagaacg gttaaggaaa ataatcgtgt ttcctatata gatggaaaac
    17401 aagcgacgca aaaaacggag aatttgactc ctgatgaggt tagcaagcgt gaaggaatca
    17461 atgctgagca aatcgtcatc aagataacag accaaggcta tgtgacttca catggcgacc
    17521 actatcatta ttacaatggg aaggttcctt atgacgctat catcagtgaa gaattgctga
    17581 tgaaggatcc aaactaccag ctaaaagacg aggatattat cagtgaaatc aagggtggtt
    17641 atgttatcaa ggtagatgga aaatactatg tttaccttaa ggatgctgcc cacgcggata
    17701 atgtccgtac aaaagaagaa atcaatcggc aaaaacaaga acatagtcag catcgtgaag
    17761 gagggacttc agcaaacgat ggtgcggtag cctttgcacg ttcacaggga cgctacacca
    17821 cagatgatgg gtatatcttc aatgcatctg atatcattga ggacacgggt gatgcttata
    17881 tcgttcctca cggcgaccat taccattaca ttcctaagaa tgagttatca gctagcgagt
    17941 tggctgctgc agaagccttc ctatctggtc gggaaaatct gtcaaattta agaacctatc
    18001 gccgacaaaa tagcgataac actccaagaa caaactgggt accttctgta agcaatccag
    18061 gaactacaaa tactaacaca agcaacaaca gcaacactaa cagtcaagca agtcaaagta
    18121 atgacattga tagtctcttg aaacagctct acaaactgcc tttgagtcaa cgccatgtag
    18181 aatctgatgg ccttattttc gacccagcgc aaatcacaag tcgaaccgcc agaggtgtag
    18241 ctgtccctca tggtaaccat taccacttta tcccttatga acaaatgtct gaattggaag
    18301 aacgaattgc tcgtattatt ccccttcgtt atcgttcaaa ccattgggta ccagattcaa
    18361 gaccagaaga accaagtcca caacctgcac caaatcctca accagctcca agcaatccaa
    18421 ttgatgagaa attggtcaaa gaagctgttc gaaaagtagg cg
//
LOCUS       DAVHKZ010000039        17973 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000039 DAVHKZ010000000
VERSION     DAVHKZ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17973
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.039"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(195..1619)
                     /locus_tag="VVO74_001722"
     CDS             complement(195..1619)
                     /locus_tag="VVO74_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU5695716.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVTWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2164..4443)
                     /gene="pulA"
                     /locus_tag="VVO74_001723"
     CDS             complement(2164..4443)
                     /gene="pulA"
                     /locus_tag="VVO74_001723"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU5695717.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4555..6513)
                     /gene="ligA"
                     /locus_tag="VVO74_001724"
     CDS             complement(4555..6513)
                     /gene="ligA"
                     /locus_tag="VVO74_001724"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU5695718.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEVKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6606..7784)
                     /locus_tag="VVO74_001725"
     CDS             complement(6606..7784)
                     /locus_tag="VVO74_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU5695719.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7864..8727)
                     /locus_tag="VVO74_001726"
     CDS             complement(7864..8727)
                     /locus_tag="VVO74_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU5695720.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISSHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8730..10631)
                     /locus_tag="VVO74_001727"
     CDS             complement(8730..10631)
                     /locus_tag="VVO74_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU5695721.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKFSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
     gene            complement(11332..12276)
                     /locus_tag="VVO74_001728"
     CDS             complement(11332..12276)
                     /locus_tag="VVO74_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HEU5695722.1"
                     /translation="MKKNDLFIDVSSHNGYDITGILADMGTQNTNIKISESTSYINPC
                     LNAQIEQSNPIGFYHFAWFGGDIEEAEREARYFLENVPQKVKYLCLDYEDHASGDKQA
                     NTDACIHFMEILKENGYEPIYYSYKPFTLNNIYYEQILAKFPTSLWIAGYGLNDGLAN
                     FEYFPSMDGIRWWQYSSNPYDKNIVLLDDEEATPKWKRNDTGWWYEYHDGSYPKEEWE
                     KIAGIWYYFDERGYSIASRWLKDDGKWYYLKENGAMATGWVQYKDKLYHFKEENGEMS
                     SKELVQVEGGWYYVNEDGSRSDKPALTVLPDGLIVTTK"
     gene            complement(12286..12564)
                     /locus_tag="VVO74_001729"
     CDS             complement(12286..12564)
                     /locus_tag="VVO74_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000611519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEU5695723.1"
                     /translation="MINWKVRFNLKNKTFLLRVAFALALPILAYFNLKLEDLVSWGVI
                     LDLLGKFFVNPYLVGLTIVNILNIIPDPTTSGISDSKRALEYQEPSED"
     gene            complement(12568..12867)
                     /locus_tag="VVO74_001730"
     CDS             complement(12568..12867)
                     /locus_tag="VVO74_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695724.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKVDSNRREGRLMTHLEKTTTELTTITHTVGDIQKEMVCMNDRMEEIEKGE"
     gene            complement(12878..14902)
                     /locus_tag="VVO74_001731"
     CDS             complement(12878..14902)
                     /locus_tag="VVO74_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695725.1"
                     /translation="MGIDQYLKVIKEGVFGRDVRQAIHDGIEQVYEDATFDGNANMEV
                     AKARGEHNNLSERLKNMVAQIQSLSDSAPKGVYKNIEALNTAFPKGRDGIYLTQNDGK
                     WNFWDGSKWVPGGNYQSPAQPDLEYNDIDYSAISDIELWAQIHEMYANGYDIEKGTGY
                     PIFSKTNGEIGSIITGSGTQNYWTKRTIVVEQGEVYSARIQQAANSAYYVYFLDEGGS
                     VIARAVKNKGVATKPERYYFSVPKGSKKMLILSFESGSVVWKGLSKNKLTTFTKTALP
                     GKFENDTSKLGQFRTLDRRVSTKTIQYCKTETLIRVNKSGYLFFIDTFNENEEYLKTL
                     TENVEIIIPAGTYYRLTIQTVDDREQKADVSTMYYSITCYQKSDNDFNVLNSLAHARF
                     NSNFKFQSKLYGIRKSDISRRYPAETLIDLGIEGLQSFAIDIGNNIGYAFGWYNNTSK
                     AIKFDLSTKRELERINKPDSGHDNDAVFVNGNVYIASADKRSDDVASLLYKWNIEENT
                     VTKINVSGVIGKPENGSRRIISGICSAENNPENLYIVTTDHDYNLPFDGMHKEDDYLS
                     IYYYSPQNNTGYLLWRSKWDELYVQGATAVNDIMYIACNHQHTSTEGYKGIVIKVIDL
                     VARMQVDEIELIGDFEPESINHVYENGNLYLLLGIAKYNSFSKVVKIKID"
     gene            complement(15080..16255)
                     /locus_tag="VVO74_001732"
     CDS             complement(15080..16255)
                     /locus_tag="VVO74_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEU5695726.1"
                     /translation="MYAVSLINGANVTPIHDSEAGGNKLLSAIVKLEINKVGQFNFQF
                     LPNNAGYKALIKPLQTMVQVVNMMTGKEIFYGRIVPVTNDMAESGVFTFAYNARSELD
                     FLNDSKQRQMLYQGKKSDFVRMILSFHNENLESYKEFYPGDLADLIATGDKMEAEVDP
                     SKSTLATLTDLILNEYGLEMKIRKEEGKKYLDFKRRIGKDSNTAIKLSVNLLTLKQHI
                     DPGGIVSRLLVYGKQNSKTNKRITISSVNNGKDYLDRADLISEYGIRMETVVFDEIED
                     PVKLKKAGEEQLASQKAVSYQYHVSAVNLSHINPNFDEFEEGDTYPVINPVMNIDERL
                     RVVARQIDLLNVERSSLTIGEKFKSAEEWQLDNIRKQTRQLVTANQLKEQQARLEEV"
     gene            complement(16318..16488)
                     /locus_tag="VVO74_001733"
     CDS             complement(16318..16488)
                     /locus_tag="VVO74_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000372136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695727.1"
                     /translation="MDQITDKIVVEVPKQDSQPVYLQVDGQTFAKLIVGHISNEQAQR
                     MIILDQGGAVGW"
     gene            complement(16488..17771)
                     /locus_tag="VVO74_001734"
     CDS             complement(16488..17771)
                     /locus_tag="VVO74_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695728.1"
                     /translation="MPEGSLKNLTEGLNLSFATIGSMFDVLFGSLNEKDNIDLLTKLG
                     MDSNTAQTIITTTTQIRDSISSALETAINLASDGAGKIADFFEWFKKGGVAVDALKSA
                     VVGVTSAWAGYKIATSIITGVEKVRNVVLGVSNGLMIARAVHTGALTTAEGAHAAATV
                     AGTGAMTTFNAVMAANPIMMIVLAIGALVAGLIWFFTQTETGQKIWSSFVEFLSNAWN
                     FVVNVGTKLWQDLADFFSLLWNSITTAAQYYWNSLINFFTNIWSKISTVGQFFFNMIY
                     NSISTVWSSISSFVSDTLNTIFNTVSSVFNNVWVTVTNIWNGIKNSISDAIEGAKNIV
                     SNTIEKIKGLFNFEFKWPHLKMPHFTFEGSMNPLEWAEKGVPSIGVEWYAKGGIMTGP
                     TVFGMNGNNLMVGGEAGPEAVLPLNKETMGMLQAL"
BASE COUNT         5384 a         3868 c         3042 g         5679 t
ORIGIN      
        1 aactccaatg tattatatat agtaaaatga aataataaca ggaaaaatcg atttctaaca
       61 atattttaga agtagagctg tactattcta gtttcaatat actataatac caaaaagttc
      121 gtattttttc tataattatt attattttat agcaaaaaaa taaaaccagg aaaacaattt
      181 cctgatttta cacgttattt cacatcaaaa acaatggatt tgacatttgt catcgcttca
      241 atgctatatt taattccttg cactccagct ccagaacctt tgacaccaag gaatgggaaa
      301 ttatctggac cacgctgggt tttattatta atgtggactg tacctacttc aagtttttca
      361 gcaatttcaa aggctttttt gaaatcattt gtaaagactg atgattgaag gccgaattca
      421 gattcgttgg caaaggcaat agcttcctct acactagcca cacgaatgat tggtaaaaca
      481 ggaccaaatg gctcttccca tgtcactttc atatcttttg taacttggtc aaaaagcact
      541 ggccagagga gattgccctc acgtttgatt ggtgtaagag cctgagcctc tttttcttgt
      601 gcatcctcaa tcaagcccca aatgaagtcg gctgaagcat tgtcaataac aggtgtaata
      661 tcagcattgt caaatggatc accaactgtt aatttagaaa cttcttcctg aagcaaagta
      721 gctaatttat ctgctacact ttcgagaaca atgacacgtt taatggccgt gcaacgttgt
      781 cctgagtagc taaaggctcc cgcaacaatt tgcttggcag catgttccaa atctgcatct
      841 tctagtacaa gagctgcatc tttcccacca agttccaaca tgataggacg cataccagct
      901 aaacgaccaa tacgttctcc aataggagtt gaacctgtaa agttgatgaa gttgacttct
      961 ttgtgctcaa tgatataatc cccaatttct gaaccacgac ctgtaatggt gttgaaaaca
     1021 cctgccggaa tccctgcttc ttcaaatgct ttagccaaca agagtccaga aatggaacct
     1081 tgtgttggtg gcttcaacat gaccacattc cctgcaatca aggcaggtgc aattttagaa
     1141 gcagataaat taactggata attaaaggga gcaatcgcta gcacgatacc aactggttca
     1201 cgacggacaa cagccagttt gtttttactt gctgcctcaa aaccaccacc ttccattgct
     1261 tgtccagtga tacggagacc ttcctcagca gcataacgaa tcaagtctgc tgtacgcact
     1321 acttctccaa ttgctgcttt aatccctttt gctacttctt tggcaaggat agtaccaatt
     1381 ttttccttat cgcgttctaa aatagctgct gttttatgca aataagccgc acgttcaatt
     1441 gctgataaag ctcgccatgc tggcagggct gcacgcgcag cttgcatagc ctcatcagct
     1501 tcagtctgag tcatggctgg aactgtaccc aattcttctt gattgattgg tgaataaatc
     1561 gtaatttctt gttcagatga tttccatttt ccatttacta aattctgata tcttgtcaaa
     1621 ttcttgtcct cctgaaaatg attaagatat attttaccaa attttcagaa aatcacaacc
     1681 ctttttgcaa aatttttgag attattttca caatcttgat ttttcaaagt atactcaata
     1741 aaaattaaaa aaatccacta cgtcaaggcg aggctaatgt ggtttgaaga aattttcgaa
     1801 gagcgtgaat gagtatcatc tatagtaaaa taaaaaaact gaacaatttg gttggggaca
     1861 gccaaaccaa tttctcacaa tgtttcagaa acaagggtgt gctattccaa tttcagccta
     1921 ctataactgt catagattgc tgaaacaaag tctaggtaaa agtcttcata ataaaaagac
     1981 ctcctatcaa gtgttcaaaa actttgatag gaggtcttgt tttgtgaaaa tatttatcaa
     2041 attttctata caagtgagct gttagccagg ttctttctat tctttcaatt tcaatgaatg
     2101 gattttttac taatactcat aactgggaat ttgtctgtgt aaaaatagcg agatagatgg
     2161 tatttataaa acactcaaga cagctagact aatatcattt aaaacattat cttcttttga
     2221 gcgactgttg gttaccaaca tagctaaatt tcctgcattt tcaaattgat agggttctga
     2281 tttagcattc acaactacca agaggtgttc tttgccgtga acttcataga taaggcagcc
     2341 gctatgttca atcgcagaat gcacaaagac atgatggtaa atttcatcat agctagagta
     2401 agaaaaggca ccagtttttg tcttcaatcg gatgacttga cggataaact caatactgtc
     2461 ttgacgctca ttaatcaagt tccagttcac ttggttcaca ctgtcaggag cattatagct
     2521 attcatcgca cgctctctat catcatgggt caactcacca ttttcaccag tcgcaaccag
     2581 tttggtacga ccaaattctt gaccgatttc cataaaggcc atcccctgca tgagcagatt
     2641 catggctgtg gcagtttcga ccttgcgcat gatttgctct gaactttggt ctggatgaag
     2701 ggttgccaat aaatcgtgaa gattgtaatt gtcatgggct tctacatagt taagcacctg
     2761 atttggatgt gtatagcttc ctaattcacg acttcctagg attgctttag ctagaattgg
     2821 ctctgtcgca gcaccactga caaaacctga cttgatagca ccataaactt ctcccccttt
     2881 gacagcatcg cgctgattgt cattaaagaa accaatattt ggcatctggt aggcattgtc
     2941 cttcttggcc ttatcataag gggcaagacc tgttcccata tcccatcctt ctccatagag
     3001 gataatgttg gagtcgattt catccaagct ttgacgaatc atctgcatgg tcttgacatc
     3061 atgaatcccc atcaagtcaa aacggaagcc gtcaatatta tattcctgca cccagtatag
     3121 aagagaatca atcatatact tgcgaaacat ttcgtgttca ctggctgttt catttccaac
     3181 acccgttcca ttctggaagg taccatctgg attcatacga taatagtaat cagggactgt
     3241 tgtttggaat ggtgcatcaa caactgagaa ggtatggtta tagactacat ccataatgac
     3301 tccaataccc gcatcgtgat aagcttgaac catcaccttc aaatcacgaa tgacctgagc
     3361 tggatcatct ggattagttg aaaaactagt ttctggcgcg ttatagtttt gtggatcata
     3421 accccagttg taggttacat ttccatcctc atcgtattct ttatgacggt ctgcaattgg
     3481 ttgcaattga acataattgt agcccagctt cttgatgtaa tcaaaagcag ttgactggcc
     3541 gtattggtta actgttccag cctgagcagc acccaagaaa gttcctcgaa gatgttcatc
     3601 tacacccgat gtaggtgatt tagtcaaatc acgaatgtgc atttcacaga taactgcctt
     3661 acatggattt tccaagcgcc aagtagcctc cgaaccgtgc ttaacctcga agttttcaac
     3721 ttgcttttct acatggctca gaatagctga acgtttgcca tcagggctgg tcgcgattgt
     3781 ataaggatca cgtgtcagtg tttggtgatg agggaattgg acttgatact gataagtctt
     3841 acctaccaaa tcttcttcaa catccaaact ccagacaccg attgtattgt ccttatgatt
     3901 ataagagtag ctattgcctc ttttcatctc aaaagtcttc caaacgggtg catcattagc
     3961 agctgattca taaacgacaa cttgcacttc tgtcgctgta ggtgaccaga gagaaaaatg
     4021 agcctgattg tcctctacac ggcaacccaa ttctccttgg taaccccaat gatgatcaaa
     4081 actagcactg ttaatggcct tatcaaaggc aaaaggattt tgatttttat agaaaggact
     4141 ggcaatagca ggattttcag agtaataaat cctatcatcg ccttccaaaa tccagacctc
     4201 tgttaatagg ggatagtgat taaaacggat agaatattct ttactagttt gacctgtatg
     4261 aaccacaaaa ttcaagcttt ctataacatg tgaacttggg tgttcaaagc taaataaagc
     4321 tccaaaataa tcttctttgt aggttagcaa atcaattcgt tgatcctgac tttttacaaa
     4381 ggagcaagtg tcatattctc cattcttacg atggtaatga atgcgcatag ggtagttata
     4441 cattttttat ttttcctttt tactttgttt ctatttcact aataaatttt tgtcaatctc
     4501 gtctcaatta acagacatag tcatattctc taaactctgt ttttaaacga tccattacaa
     4561 actttctagc catgcctcat ctctgacctg gataccaagt tcttgtgctt tttgcagttt
     4621 acttccagcg tctgcaccta ccacgacgag gtcggtcttt ttagaaatac tacctgtcac
     4681 tttggcaccc agactttcga gtttactttt aacttctgag cgcttgagtc gttccaattt
     4741 tcctgtcaat accacggtca aacctgacaa ggccgcatcc gctactaccg tctgtccttt
     4801 atagtccaga ttgaccccag tttctttcaa ttctctgagc agaatttcag agccttctgt
     4861 cgcaaaataa gtctgaagac ttttggcaat cacgccacct agactttcaa tactagccac
     4921 ttcctctgaa tctgcctgag acagattttc aattgaatgg aaatattgaa gtaaaagctg
     4981 actaaccttg cttccgacat gacgaattcc caaaccaaat aagagcttct cggcagagtt
     5041 ttcctttgat gcttggatag cctgatacag tttagcagcg gacttttcct taaccccctc
     5101 taaaaggagg aaatcctctt cttgcaaacg ataaatatcc gccacatcct tgactaaatt
     5161 agcagcaaaa agcttctcaa caatagatgg accaaggcct gtaatattca tagcatcacg
     5221 agaagcaaag tgaatcaagc cttccatgat ttgagcaggg caacgcggat tgatacaacg
     5281 tagggccact tcatcttcaa agtgcaacaa gtcagagtta caacttggac agtttgtagg
     5341 gatatctagt ttttcttcag aaacccgttt ggactctacc acacgtaaaa cggcagggat
     5401 gatgtcacca gccttatata caatgaccgt atcgtctttt cggatatctt tttcagcaat
     5461 ataatctaca ttgtgcaggg tcgcacggct aacagtcgta ccggcaagtt gtactggtgt
     5521 tagattagca gttggagtta caacaccggt acggccaact gtccagtcaa ctgataagag
     5581 ttgagcttct ttttcttcgg cagggaactt gtaggctact gcccactttg gagccttaac
     5641 ggtaaaacca agttcttctt gacttgctag gtcgttgacc ttgattacca ctccatcaat
     5701 atcgtaaggc agattttccc gttcctgtcc tacttcttgg ataaaattcc agatttcatc
     5761 tatgttttca gccaagattc gcttaggatt gaccacaaaa cctagttgtt ctaggtactt
     5821 caaacccttt tcttggctat cacgagttga agggctggct tcttgataga gaaacgttgc
     5881 aagattacgc ttggcaacta ctgctgtatc caactgacgc agagttcctg ctgccgcatt
     5941 acgaggatta gcaaattcag gctctccatt ttcttggcgc acttggttaa cttggtcaaa
     6001 ggaagcgcgt ggcatgtaac attccccacg aactgtgata tctagttctt ctggcaaagt
     6061 caaagggatg tccttaacac gcttgaggtt ttctgtgata ttttcaccaa ttgaaccatc
     6121 tccacgtgtt accccagcaa ccaaaatccc cttttcataa gtcagcgaga tagataagcc
     6181 atcgattttc agctcacaaa tataggtcgg atgagccact tccttacgaa cacgcgcatc
     6241 aaaagcatct agctcctcac gtgaaaaagc atcctgcaaa ctataaagag gatactgatg
     6301 actgtatttt tcaaaaccat ctaaaacctt gccaccaaca cgatgagtcg gactgtctgc
     6361 tagcacttgc tctggataag cagtttctaa ctcgaccaac tcacggtaaa ggcggtcata
     6421 ctcactgtct gaaaccgagg gattatcgct ggtatagtac tcagtcgcat agcgattgag
     6481 caaagcgact aactcattca ttcttttatt cataagacca ttttaccata aaacaagccc
     6541 tcctcacaaa cgagaagggc ggaaaaaaca cttagtttga aattattttt gaaactcaag
     6601 caaccttata tcaatttttc aaaatgagtt cgaacataaa taaacgatat acaagacaag
     6661 atgataacac cacttccaat tatcaggaaa gaagagagat gtacacttgg caagactgtc
     6721 ataaatcctt ttgcaatagg cataaataga atagctaagg taaaaattgt actcagtact
     6781 cttccaagaa attcgctctc aaccttggtt tgtacttgag taaaaaagtg aatattaaaa
     6841 atcgtcataa acaattcaca aactaaattt ccagaaaagg aaagaaaagt tggaagtggt
     6901 aatcccatca taaaaactcc gacacctgtc aaagccagta aaatcaaaag attataaata
     6961 ttagctttaa ttttactagc tagaagagcc ccaatgatgg aaccaatagc ccccatagtt
     7021 aaaatacttg cataggctcc ttctgacccg taaagctgat tcgaaaaggg aagtagaaat
     7081 tcaaaagctg caaaaaagaa attaacgctg gaagctacca gcaaaaggaa gaaaatttct
     7141 tgctgatgcc agatatagtg taacccatcc ttgatatcta caaaaatatc tctcccagta
     7201 aaagcctttt tctcttgaac ttttgcttcc tcttttggaa ggaaagccac tagaacaaaa
     7261 gcaatgaaaa aagtcagcga gtctagcagt agcgtcatat ggagacttgc aaactgtaaa
     7321 acaaggaagg aaagaacagg agagctaaca cctacaacct gcaaaaccag ctctaggcga
     7381 gaattataga tcacaatctc atctttctcc accacttcag ttatgatagc tttattggct
     7441 gtgcgagaaa aggcaaaagc aatagcctgc acaatgttag caacaatcaa agcgccaatc
     7501 atccagctat cattccttat gaaagaaata gccagacaaa gaatcccaca aacaagatct
     7561 gccgtcatta aaatcttacg acgagaaaaa cggtctgaaa taactccgcc aaagggattg
     7621 acgagaatag atgtgacgag ctcagaaatc tgatacattc ctaaaactgt ctgtcctata
     7681 gtccccatag aagccaacca gacactattt ccataatcat agagcatatt tcccatttta
     7741 ttgatagccc cacggctaat caactgcact gcatagcgat tcatattaaa gctcctctca
     7801 aattttgaaa ctattgtatc aaaaccgaaa ggagcttttt attttttccc ttatttggga
     7861 aaattaactt ttgacaaatt tttcgtagtg ttcctgataa taggctactt gctctggaag
     7921 acctaacaca tcaaaaatat gtatggcctc ttgcatctgc ttacagcctt ctttacactg
     7981 tcctttttga tataaggcaa aaccttttaa ataatggaaa acattacgct cataaagctt
     8041 aatacctttg tcaataatct tctctgtata agcctcaaaa tagttggcat tataaaaaga
     8101 agaatgctct aaacaatgct ggtaacaatt gagggccaaa atcaacacta atctcttatg
     8161 gctactaatc tcttggtaaa attcctccct ctccataact tctctaccaa tccgagtgac
     8221 ataatccaca tcgtagaaac tatagaggtt accgaaaaga atcaactcat acatggtcca
     8281 ttcttctgtt ttgaagagat aatctgctac cttatccaaa tcatcctgct tcatatcata
     8341 actcgcatct ctttgacaaa tcagaccctg tagcaaaatc cagttcagct caaaataaag
     8401 gggagtcgtc gaactcttag acttttcaag ttgttctctt tgaagctttt gaaaacctgc
     8461 aatatcgttt gaatagtaaa gtgggataat ctgtgccatc atagacacat gttcatgatt
     8521 atgaaaattc cttgccttat ccatgaaatt ttcgattgtt acatgaatgt tatccaaaat
     8581 ctcaaagaaa cgggagactg ccaggtcaga ctccccaagc tcaaagcgag ataactgaga
     8641 ggtagagcag gattcgcctg ctgcttcctt caaagaataa tttccacttg ttcgaaattc
     8701 acgaaatact tttccaagat gttccatctt tacacctgct ctgataattc ttcccactca
     8761 agcatagctt cttcctgacg atggctgatt ttgtccagct cagcctgtaa ttccatgagt
     8821 ttgtcggcat cgtttgtttc caacatttgt tcagaaatgg cttggctttg actttctagc
     8881 tcttcaattt cagcttctag actttcgatt tgtcgcatga gtttgcgaac ttctttttga
     8941 ctttctttct gggcctgata gtcattgact ggacttgctt cctttgcttg attgctagtt
     9001 gaagcttcct cagtctgact catttctgct gttgctttct tctcaacata gtagtcgtaa
     9061 tctccaaggt agagagttga accattctca gacaattcca aaacatgagt tgccacacga
     9121 ttgataaagt aacgatcatg actgacaaaa agcaaggtac catcaaagtc aatcaaggca
     9181 ttttctagca cttccttact atcaatatcc aagtgattgg tcggctcatc cagaatcaaa
     9241 aagttattgt tttccataga aaatttagct aaaagcaaac gagctttttc gccaccagat
     9301 agcatgccga ctgatttttt aacatcatct cctgagaaaa ggaaggctcc aagacggttg
     9361 cggatttcaa cttctggtgt cagtttgaaa tcattccaga gttcatccag caccgtatta
     9421 cttggtgtca gcttgctttg ggtttggtca tagtaaccaa cctcaacatt agcgccaaag
     9481 cgcttttctc ccttgataaa aggaatctgg tccacaatag acttgataaa ggttgacttg
     9541 ccgataccat ttggaccaac gatagcgaca gcattcatct tacgaagatc taggttgata
     9601 ggttgtgaca agacttcccc gtcatagcca acagctgcat tttcaacagt caaaacaaca
     9661 ttgcccgacg ttttttcaga ctggaaggtc atgttggctg ctttcttgcc agcttcaggc
     9721 ttgtccaaac gctccatttt ttctagttgt ttacggcgag attgagcacg tttagtcgtt
     9781 gaagcacgaa ctagattgcg attgacaaag tcttccagag cagcgatttc cttctgttgc
     9841 ttttcatagt tttttgcctc agtaactagc ttttgctcct tcaattcgac aaaacgagag
     9901 taattcccca catagcgatc caaggaatgc ttggtcaaat ctagcgtaat tgtcgcaacc
     9961 ttgtccaaga aataacggtc gtggctgacg ataatgaggg caccgctata gtttaccaag
    10021 taattctcta gccaggcgat ggtttcaata tccaagtggt tagttggctc gtccaagacc
    10081 aagagattgg gcttttcaag gagcattttg gcaagtgcca aacgagtatt ttgaccacca
    10141 gaaagctcag caattttcat ctgccacata gactcgtcaa acttgaatcc attcaaaatc
    10201 gctcgaatat cagcttcata ggtaaagcca cctgcttggc gaaaattctc agataagcgg
    10261 tcataatctg acatcagttt atccaaatcc tcaccagact tttcacccat ctccagctcc
    10321 atctgacgca gttgtctctc cgtccgacgc aaatcattaa agacatgaag catttcatcg
    10381 tagatggtat tttcagactc aaaacggcta tcttgggcta ggtaagacag agaaatatct
    10441 tttttcttat tgatttctcc gctagttggc tcctcttctc caactaaaat cttcaaaaga
    10501 gtagacttac ctgcaccatt tttcccaaca agagcaatcc gatctcgttc atcaacctgc
    10561 aggttgatat tatcgaaaag aacctctcct gcaaaagaac gttcaatttt attagcttgt
    10621 aaaataatca taagagtagt atagcatgtt tccctaaggc attcaagata atcgtaagtc
    10681 ttttagtaca acttttataa cataaaataa actaaattat gtatatttta tattagattc
    10741 ttcactatct tgttggattt tctaaccagc taatcttgtt tcaaatagtt atcgcacaag
    10801 cctattattt aattcttttc attatttacg tacgtatagc agattgaaat aagatgagaa
    10861 caaatcgatt gggaaagtaa aattaatttc tataaatgtt ttagcaattg tttcgtacta
    10921 ttttagattc agtctactat atacaatatt ttcggaacat tcaacttttt aactctattt
    10981 attactagat ttcataatta aaaagcctac tgaccaagct agaaagcttg atacaatagg
    11041 ctttttaaag actgattatt taacagcgtc tttaagagaa aatggtttta gataagattg
    11101 cataagtcaa aagcctttta aaataagcct ttatacgtta taaagtacat atacttttta
    11161 ccataaaaat acaaaagttt tcaccttttg cccctttgat tatctacttt tgtaactttg
    11221 gtaccgacat caatgtcggt tagttagata ttttcttaat tcagacaaac aaaaaaaccg
    11281 caagctattg cctgcggttt gtgtaatcta atttgaaaat tctttctgtt tttattttgt
    11341 ggtaacaatt aaaccgtcgg gcagaacagt aagcgctggt ttatctgaac gactgccatc
    11401 ctcgttgaca tagtaccagc cgccttcaac ttggacaagc tcttttgaag acatttcgcc
    11461 attctcttct ttgaaatggt atagcttgtc cttgtattga acccaaccag tggccatagc
    11521 tccattttct ttgagataat accacttacc atcatccttc aaccagcgag aagctattga
    11581 ataacctctc tcgtcgaagt agtaccagat tccggcaatc ttttcccatt cttctttggg
    11641 ataagatccg tcatggtatt cataccacca tccagtatca tttcttttcc atttgggcgt
    11701 agcttcttca tcatctaata aaacaatgtt cttgtcatac ggatttgaag agtattgcca
    11761 ccagcggata ccatccattg atggaaaata ttcaaagtta gctagcccat cgtttaaacc
    11821 atacccggca atccaaagac tggttgggaa tttcgcaaga atctgctcat aataaatatt
    11881 attaagcgtg aatggcttgt agctgtaata gattggctcg tagccatttt ctttgaggat
    11941 ttccatgaag tgaatacaag catccgtgtt tgcctgttta tctccactag cgtgatcttc
    12001 gtagtcaaga cacaagtatt ttactttttg aggcacattt tcaaggaagt agcgtgcctc
    12061 tcgttcggct tcttcgatgt caccgccaaa ccaagcaaaa tgatagaatc cgatagggtt
    12121 tgactgttct atctgtgcgt ttaagcacgg attgatatag cttgtacttt ctgaaatttt
    12181 gatgttggta ttctgtgtac ccatgtcagc caaaatacct gtaatatcgt atccattgtg
    12241 gctagatacg tcgatgaaca agtcgttttt cttcattgtt ttctcctaat cttcgcttgg
    12301 ttcttgatac tcaagagcac gtttgctatc agagattcct gatgttgttg ggtctggaat
    12361 gatatttaga atatttacaa tcgtcaaccc cacaagataa gggttcacaa agaatttgcc
    12421 aagcaagtct aaaatgactc cccagctaac caaatcttct agtttaagat taaaatatgc
    12481 gagaattggc aaagctaaag caaatgccac tcgcaataag aatgttttat tttttaagtt
    12541 aaatcgtact ttccagttga tcatgtgtta ttctcctttt tcgatttctt ccatgcggtc
    12601 gttcatacag accatttctt tttgaatgtc tccgaccgta tgagtgattg tggttaattc
    12661 tgtagtggtt ttttccaggt gagtcatcaa acgcccttct cgtctgttag agtcgacctt
    12721 tgactgctcg tgcaaatcca taatcttctt ctctcgcttg tccgaagtct tgataagata
    12781 tcgaatgata ataaagaaaa gcaagataaa caaaatcgcc caagctacct gactttgagc
    12841 gattttttca gcttcttcaa tcggcatata acctccttta atctattttt atttttacaa
    12901 cttttgaaaa agagttgtac ttagcgatac ctaaaagcaa atatagattc ccgttttcgt
    12961 atacatggtt gatgctttca ggctcaaagt caccaataag ttcaatttca tcaacctgca
    13021 tacgtgcaac taaatcaatg accttaatca caattccttt gtagccttca gttgacgtat
    13081 gctgatgatt acaagcaata tacatgatat catttactgc tgttgcacct tgaacataca
    13141 attcgtccca tttagatctc cacaaaagat atcctgtatt attttggggc gaatagtagt
    13201 atatcgatag ataatcatcc tccttgtgca ttccgtcaaa cggaagattg taatcatggt
    13261 ctgtagtcac aatatataga ttttctggat tgttctctgc tgaacaaatt cctgagataa
    13321 ttcttcttga gccattctcc ggcttaccaa ttactcccga aacattaatt tttgttacgg
    13381 tgttttcttc aatattccat ttatacaata agcttgcaac atcgtctgaa cgtttatctg
    13441 cagaagcaat ataaacattc ccgttcacaa aaaccgcatc attatcatga cctgaatctg
    13501 gtttgttaat tcgctctagt tctcgtttcg ttgataaatc aaatttgatt gctttcgaag
    13561 tattgttata ccaaccaaac gcgtaaccaa tgttattgcc aatgtcaata gcaaatgact
    13621 gtagaccttc gattccaaga tcaattaaag tttctgcggg gtatcttctg ctaatatcag
    13681 attttcgaat tccataaagt ttcgattgaa atttaaaatt cgaattgaaa cgagcatgcg
    13741 caagcgaatt cagaacattg aaatcattgt cagatttctg ataacatgta atcgaataat
    13801 acatagttga tacatcagcc ttctgctccc tatcgtcaac agtctgaatc gttaatctgt
    13861 agtaggttcc cgccggaata ataatctcaa cattttctgt tagtgttttc agatattcct
    13921 cattttcgtt aaaagtgtct atgaagaaca aatagccact tttattcaca cgaatcaatg
    13981 tctctgtttt acaatattga attgtttttg tcgaaacgcg tcgatccaat gtcctgaatt
    14041 gccctaattt tgatgtatcg ttttcaaatt ttcctggtaa tgcagttttt gtgaatgttg
    14101 taagtttatt cttcgacaat cctttccaaa caacagaacc agattcgaat gagagaataa
    14161 gcattttttt gctccctttt ggaacgctga aatagtatcg ttcaggtttt gttgctacac
    14221 ccttgttttt aactgcacga gcaatgaccg agccaccttc atccaaaaaa tagacataat
    14281 aagcagaatt ggcagcttgt tggattctgg ctgagtaaac ctctccttgt tcaacaacaa
    14341 tcgtcctttt cgtccagtaa ttctgtgtac ctgaaccagt aatgatcgag ccaatttctc
    14401 catttgtttt tgaaaaaatc ggatagccag ttcctttttc gatatcatag ccatttgcat
    14461 acatttcatg gatttgcgcc catagttcaa tatcactaat agctgaatag tctatgtcat
    14521 tgtattcgag atcaggctga gctggacttt gataatttcc gccagggacc cacttagagc
    14581 catcccaaaa attccacttg ccgtcgtttt gagttaggta tattccatct cttccttttg
    14641 gaaaagcagt gtttaacgct tcgatatttt tgtaaacacc ttttggagca ctgtcagaca
    14701 aagattgaat ttgagctacc atatttttta atctttctga aagattatta tgttctcctc
    14761 tcgccttagc cacttccata ttcgcgttgc catcaaatgt tgcatcttca tagacttgtt
    14821 ctataccgtc atgaatagct tgtcgaacat cgcgaccaaa aactccttcc ttgataactt
    14881 ttaaatattg gtcaattccc atttaaactt tcctttctag attttcaatt cgtttcaata
    14941 gatcatctaa gtcaactttc tttgaaatta gcaaataatc cagttttttc ttatcttgag
    15001 cagataagag ttggctagac tgttcgttca ccgtattatt gacagtttca actgtctctg
    15061 cagctgtatt agcaataact cacacttctt ccaatcttgc ctgttgctct ttaagctgat
    15121 tagctgtaac taattgccga gtttgcttac gaatattatc taattgccac tcttccgcag
    15181 acttaaattt ttctccaatc gtcaaactag atctctcaac atttaataaa tcaatctgac
    15241 gcgcaactac tcttaaacgt tcatctatat tcattacagg gtttattacc gggtaagtat
    15301 ccccttcctc gaattcgtca aaattcgggt taatatgaga caagttaaca gcagaaacat
    15361 ggtattgata actaactgct ttttgtgatg ccagttgttc ttcaccagcc ttcttcaatt
    15421 taacagggtc ctctatttca tcgaatacaa ctgtttccat tctgatacca tactctgaaa
    15481 tcaagtctgc tctatcaaga taatcttttc cattatttac agagctaata gtaatccgct
    15541 tattggtttt actgttttgc tttccgtata ctagcaaacg ggaaacaatg ccacctggat
    15601 caatatgttg cttgagtgtt aataaattta ctgataactt gatagcggta ttactatctt
    15661 taccaattct tcttttaaaa tctaggtatt tcttcccttc ttctttccga attttcattt
    15721 ctaagccata ctcattcaaa atcaagtccg tcaaagtcgc tagagttgat ttgcttggat
    15781 caacttcagc ttccatttta tcgccagttg cgatcaaatc tgccaagtct cctggataaa
    15841 attctttgta cgactctaag ttttcattat gaaaactcaa aatcattctg acaaaatcag
    15901 attttttccc ttggtataac atttgtcgtt gtttgctatc atttagaaaa tctagttcag
    15961 atctagcatt atatgcaaaa gtaaatacac cactttctgc catatcgttt gtaaccggca
    16021 caattcgacc atagaatatt tctttaccag tcatcatgtt gacaacctgg accattgttt
    16081 gtaagggttt aattagagct ttgtaaccag cattattcgg cagaaattgg aaattaaact
    16141 ggccaacttt gttgatttct aatttgacaa tcgcagacaa aagtttgttc ccgcctgctt
    16201 cagaatcgtg tatcggtgta acgttagcac cgttaatcaa actaactgca tacatctaaa
    16261 tcagctcctt aaaccactta aacgagatcc tgccattgaa atttacggca tatcctctta
    16321 ccatccaact gcacctcctt gatcaagaat aatcattctt tgagcttgct cattactaat
    16381 atgcccaacg attaactttg cgaatgtttg gccatccact tgcaaatata ccggttgtga
    16441 atcttgtttt ggaacttcaa caacaatttt atcggttatc tgatccatta taaggcttgc
    16501 agcataccca ttgtttcttt gttaagaggc aagactgctt caggtccagc ttctccacct
    16561 accatgagat tgttgccatt catcccaaac acagtcggtc cagtcatgat accaccttta
    16621 gcataccatt ctacaccaat gcttggcacg cctttttcag cccattccaa aggattcatc
    16681 gatccttcaa aagtaaaatg tggcatcttc aagtgtggcc atttgaattc aaaattgaac
    16741 aatcctttaa ttttttcaat tgtatttgaa acaatatttt ttgcaccctc tatagcatca
    16801 gaaatactat ttttaatacc attccaaata ttcgtaactg taacccatac attgttaaaa
    16861 acactagaaa cagtattaaa tatcgtattc agagtatcac taacaaatga gcttatagat
    16921 gaccatactg ttgaaattga gttgtaaatc atgttaaaga aaaactgacc aactgtgctt
    16981 attttcgacc aaatattggt gaaaaaattt attaaagagt tccaataata ctgagcagca
    17041 gttgttatcg aattccacaa aagtgaaaag aaatcagcta gatcctgcca aagttttgtc
    17101 ccaacattga ctacaaaatt ccaagcattt gatagaaact caacaaaact agaccatatt
    17161 ttttgtcctg tttcagtctg cgtaaaaaac caaattaaac ctgctactaa ggcacctata
    17221 gctaacacaa tcatcataat cggattggcg gccattactg cattaaatgt tgtcatagct
    17281 ccagtccctg ctactgttgc agctgcgtgt gcaccttctg cagtagtcaa agccccagta
    17341 tgaacagccc tagcaatcat taatccatta ctaacaccca acacaacatt tcgtactttt
    17401 tcaacacccg taatgatact agttgctatt ttgtatccag cccaagcact tgtaactcca
    17461 acaaccgcag attttaaagc atcaacagcg actccgcctt ttttgaacca ctcgaaaaag
    17521 tcggcaattt ttcctgcccc atctgatgcg agatttatag ctgtttcaag tgctgaacta
    17581 atactatctc taatttgggt tgtagtagtt ataatcgttt gggcagtatt cgaatccata
    17641 cccagttttg tcaacaagtc aatattatct ttttcattca atgaaccaaa tagtacatcg
    17701 aacattgaac cgatagtagc aaaacttaaa tttaaacctt cagtaagatt tttaagactt
    17761 ccttcaggca acttaaaaac cttttctaaa aacgtaacaa aagcttgaga tagttgagga
    17821 agtatatcat tgaataaaat taaaaaaagt ctcggcaaag cagatcctaa ctcgctaaga
    17881 agttctgttg ccccagttat aagtccaggt aataaagcac taagaagatc aggtaaatag
    17941 ttccctaaaa tctgaataat gcgagataat ccc
//
LOCUS       DAVHKZ010000040        17438 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000040 DAVHKZ010000000
VERSION     DAVHKZ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.040"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(68..316)
                     /locus_tag="VVO74_001735"
     CDS             complement(68..316)
                     /locus_tag="VVO74_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU5695729.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRMEQATLEVLNTISLNRKYIRSNLDK"
     gene            complement(482..707)
                     /locus_tag="VVO74_001736"
                     /pseudo
     CDS             complement(482..707)
                     /locus_tag="VVO74_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1555..2427
                     /locus_tag="VVO74_001737"
     CDS             1555..2427
                     /locus_tag="VVO74_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU5695730.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDTFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTESTTDVKVHAEKMEAFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2573..2917)
                     /locus_tag="VVO74_001738"
                     /pseudo
     CDS             complement(2573..2917)
                     /locus_tag="VVO74_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3060..3371
                     /locus_tag="VVO74_001739"
     CDS             3060..3371
                     /locus_tag="VVO74_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695731.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKKREELRQIITTIFEQKMNKHSI
                     K"
     gene            3375..4091
                     /locus_tag="VVO74_001740"
     CDS             3375..4091
                     /locus_tag="VVO74_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU5695732.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(4220..5035)
                     /locus_tag="VVO74_001741"
     CDS             complement(4220..5035)
                     /locus_tag="VVO74_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU5695733.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5032..5937)
                     /locus_tag="VVO74_001742"
     CDS             complement(5032..5937)
                     /locus_tag="VVO74_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU5695734.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMFFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            complement(6267..6350)
                     /locus_tag="VVO74_001743"
                     /pseudo
     CDS             complement(6267..6350)
                     /locus_tag="VVO74_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            6394..8523
                     /locus_tag="VVO74_001744"
     CDS             6394..8523
                     /locus_tag="VVO74_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU5695735.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            8510..8959
                     /locus_tag="VVO74_001745"
     CDS             8510..8959
                     /locus_tag="VVO74_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU5695736.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTQRYRCGLCRGKLLLVNQPED"
     gene            9017..9289
                     /locus_tag="VVO74_001746"
     CDS             9017..9289
                     /locus_tag="VVO74_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU5695737.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(9337..9501)
                     /locus_tag="VVO74_001747"
     CDS             complement(9337..9501)
                     /locus_tag="VVO74_001747"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695738.1"
                     /translation="MDEAGEILLILFKNQSANYINFTLPTKLQPAAGFLVCTLIFIEY
                     KSKKALNQAV"
     gene            complement(9643..9834)
                     /locus_tag="VVO74_001748"
     CDS             complement(9643..9834)
                     /locus_tag="VVO74_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695739.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            10262..11020
                     /locus_tag="VVO74_001749"
     CDS             10262..11020
                     /locus_tag="VVO74_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695740.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVASAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            11022..13010
                     /locus_tag="VVO74_001750"
     CDS             11022..13010
                     /locus_tag="VVO74_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5695741.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFLAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(13052..13696)
                     /locus_tag="VVO74_001751"
     CDS             complement(13052..13696)
                     /locus_tag="VVO74_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEU5695742.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATSNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYASYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(13722..14717)
                     /locus_tag="VVO74_001752"
     CDS             complement(13722..14717)
                     /locus_tag="VVO74_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU5695743.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVRKSSVTKELKEKILHYHNQ
                     KFSPEMMVMVKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSADVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGIKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSVRNKSRN"
     gene            15424..16899
                     /locus_tag="VVO74_001753"
     CDS             15424..16899
                     /locus_tag="VVO74_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU5695744.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(16865..17421)
                     /locus_tag="VVO74_001754"
                     /pseudo
     CDS             complement(16865..17421)
                     /locus_tag="VVO74_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5252 a         3224 c         3626 g         5336 t
ORIGIN      
        1 aaataagata tgcacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagcaa
       61 tcgcaatcta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaacctccaa agtagcttgc tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa
      241 ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag
      301 tatttgcctt ttgcaaagtg atcttaaatg cctttctcta aatttacata tcactattgt
      361 ttaacaaaat ctaatctact ttaggtcact tattcttttt tgcaatgtag aatgaacttt
      421 ttcaaagttt ttcgaatctt ttaaaatctg tttgttttat atcgccattc tccccccttt
      481 tttaattctc cctatatagc ctgacaactt tcccgatggt acaaatatgg ttgctttcgt
      541 ctaggtggat gtcggggtat tcgggattga gtttttttga ggtagccttg gcggagtttc
      601 ttgacatagt tagcgccgtc tacttggaag atgccgatgg tattatagtc aatctgtggg
      661 gtattcttga taaataggta gtcgctgttt cttatctttg gctccatgga cttgctgacg
      721 acataagcga ttgggtcgta gtcgtctggg ataatggaaa ctccatatct aaatcgttgt
      781 cctgcatcga gcggctacct gcagagataa actacctaac aagagagtaa gtagtctgtc
      841 tgtagtcgtc cagtctgatg atttttacga tacttcgttt ttctgatcat acagttgcct
      901 ctcggcatag gtcagaactt taccttgtct gggtggtgcc cgttggtcgt agatagattg
      961 gatatcgcta ggagaatcct tttgaactgg aggaaagagg gcatcaatca agctactgaa
     1021 tactttaact aagtcaaata tagtattttt cttagtagac ctaacccttt tttcataatt
     1081 tctaatggtg tttttactta tacctatctt agtacccaat tcttattgag tccaaccatt
     1141 actagtctat attgttttat agttgattga gtttggaata gtacgctgta gctgctaaaa
     1201 catttctagg aattaatttg cctttcctaa tagagttgtt catatcttat ttcaatctat
     1261 gatgtttttc acctctaaca atcgcaatct cttctttatc catgaatgaa aacgttttct
     1321 atttttgtaa gtaaagcatc acacgaaatt cacgaaaatg aaaacctttg ttgtgttttc
     1381 gtaaaaaatt tgttgacaga gcacgaaacg cctactataa ttaagtcaag cttaaggaaa
     1441 taacaaaaaa acaaatcgga gggaaagacg atgaacacat taaatgagaa agtaatcaat
     1501 atctgtaaag cagtagttaa agaaacttta atccaagaca tttaggagaa agaaatgaag
     1561 aaatcaagaa aattagccac attaggaatc tgttcagcct tgtttttagg cttggctgct
     1621 tgtcaacaac aacatgctac ttctgagggg acgaatcaaa ggcaaagcag ttcagcgaaa
     1681 gttccatgga aagcttcata caccaaccta aacaaccagg taagtacaga agaggtcaaa
     1741 tctctcttat cagctcactt ggatccaaat agtgttgata cattttttaa tctcgttaat
     1801 gactataata ccattgtcgg ctcaactggc ttatcaggag atttcacttc ctttactcac
     1861 accgaatacg atgttgagaa aatcagtcat ctctggaatc aaaagaaggg cgattttgtt
     1921 gggaccaact gccgtatcaa tagttattgt cttttgaaaa attcagtcac cattccaaag
     1981 cttgaaaaga atgaccagtt gcttttccta gataatgatg cgattgataa aggaaaggtc
     2041 tttgattcac aagataagga agagtttgat attctatttt cgagagttcc aactgagtca
     2101 actacagatg tcaaggttca cgctgaaaag atggaagcat tcttctcaca atttcaattc
     2161 aatgaaaaag ctcgaatgct gtctgtagtc ttgcacgaca atttggatgg cgagtatctg
     2221 tttgtaggcc acgttggggt cttagtacct gctgatgacg gtttcttatt tgtagagaaa
     2281 ttgactttcg aagagcccta ccaagcgatt aaatttgcta gtaaggaaga ttgctacaag
     2341 tatttgggca ccaagtatgc ggattataca ggcgagggac tggctaagcc ttttatcatg
     2401 gataatgata agtgggttaa actttaatag tgttatgata tgacagtaat cttaggattt
     2461 ttatttctat ttttgataag ttggtgggtt atttcaatcg ttaatagcca gaaaccacgc
     2521 aaaaatgaaa catttattgg ctatgtccaa agatacgata ttgatgggaa tggctatcaa
     2581 tcattaccgt gtcctcagaa ctgagaggag ttcttgaaat cgtaacacca ctttgaacaa
     2641 gagttactta aacccattgg ctccgacgga ttaagttgct ttcgtgaata ccaaaatcag
     2701 ccgcaatttc ttcataagtg cggtattctc gcacatattg aagagtggcc ataagaaggt
     2761 cttctaggct taatttaggt tttcgtccac cttttgcgtg tttaagttga taagctgttt
     2821 ttaatacagc taatatctct tcaaaagtcg tgcgctgaac accaacaaga cgtttaaatc
     2881 gtgcatcagt tagttgttta cttgcttcat aattcataga actactatac catattttgt
     2941 ttcgcaggaa gtctaatgct aaaatcttat cagtgagaag atttcttaaa gtttattctt
     3001 tgtagtttca tctgtattag tacataattt aacttagaga aaataggagg actaatcgaa
     3061 tggaattaaa agattttaca gaaaaagaac aggaaatgat taagaaaagg cttacaatgt
     3121 ctaatattag tgacaaagaa actactgaga agattctggc gctagtccca caagacttga
     3181 ttaagcgaat cccgtttttt gtcagaaaac atgctacaac acgtacgatt aaacgcattt
     3241 caattgaata ccctgaactc tacgctgtag ctcaaacaag tggtgagatt ccagaaaaaa
     3301 aacgcgaaga attgcgtcag attatcacaa ctatctttga acaaaagatg aataagcata
     3361 gtattaagta gagaatgaaa aaatatttta ttggcggttt gggaagcaat gcctatcata
     3421 gcaaggattt tcttcaagaa ctagattcgc aggtctattt tctaaatcca tatgaaaagc
     3481 atcttcgaga tgaaacagaa ttgaaatcat ggtttaaaaa tgaaattgta gaggaagaat
     3541 ctatctgtct gataggccat tctcttggag gagatttagc tcgttatttc gcatcggaat
     3601 ttgaagaagt aaagaaactg attcttttgg atggtggcta tctagattta gataagattt
     3661 tacctttgga tacagagtta gaggaaacta aaaattatat caaatctcaa attgtttcgg
     3721 acttagatgt tcttacttct aaagaaaaat ctgaagcaaa gcattggtca gaaaatatgg
     3781 agaaagctgt aagacagtct tatcactgga atgttgagta taatagatat gagttggcta
     3841 taaattatga aaatatagaa gcgatactcc gcctacggag aaaaatacaa gcttttaaga
     3901 gagaagtggg agataccttg tttattagtc ctcgctatcc taatgaagct acatggagag
     3961 aggaagccct aaaagaattg ccagactatt ttgatactat ttttttagaa aactttggcc
     4021 atgagcttta tactcaagca cctaaagaaa tcgctagtct aatgaatgag tggctcgctt
     4081 attttctatg agctacttgt attgctggga atggtataag atgaaaatct acaagtcact
     4141 aattttcata taacaaaaaa cgaacaggct ctttttctgt tattcagaag agaacttgtt
     4201 cgtttttatc ttgattttct taaaaagctc tatatacata gggattttct ggtttatcga
     4261 ctttggtaaa gctgtcgatt tccaaggttg gaaggttttg tttgagttct ttatggtagt
     4321 gattgaccag ttttcctttg gctgttatcc aagtgttgtt ttcatactgc cgggtattgc
     4381 ccttggtcag caatccatag acaccagaat ctgcgataca gtggataatg ccgaatcgga
     4441 acagaaattg actattggca tgactggggt cgttatagac aaagcctgta aactggattg
     4501 tcttgccctc aaactcatct ggatagtcgt agatagcctc catgacttcc atatagtttt
     4561 cattagtgat ctgaatacta tcttgggata agtatttatc cgccgccgtt cgcatttcct
     4621 tttcataggc tgattttgaa aaataagaac tggtatctgg tttcaaatat tggcttgtcg
     4681 tcccttcgct tgtctgaatg gctagatccg ttccttccga tagggggaaa tgataacctt
     4741 tagcagaaac agtctgagaa tccaagctaa cagttgggaa agttaagccg atgacaagtg
     4801 gaatagccag aagagaaata ctcgtcatct tggctaatcg gctgttcaga tgactgtggg
     4861 ttttgacttg cttcatccag atatacaatt gaacgatagc caagataaaa gaaagcacca
     4921 tggagatata ggccagatag gaatagtgca tgttgatgta ctggtttagt ttgcccgaca
     4981 gatggaggta aatagtcagt tcaaaatagc cagctaaaac taaaaatcga atcataggat
     5041 gactccaatc aagagagaat agactaagac gacaagagtt acaattgtta tgaagtgact
     5101 gataaatcgt gctttcaagt aatttttcat catgagaata tttttgatat ccagcattgg
     5161 accaatgacg agaaaggcca gaactggtgc caaaccgaaa ctcgagagaa gagaagcacc
     5221 tataaaggca tccgcctcac tacagagcga aagaagaaag gctaaaatca tcaagagcag
     5281 gatggcaaaa agaggggtcg cactgataga ggtcagaatc cgagtcggaa cgtagacctg
     5341 tattatagaa gcaaagaggc agccaaatac caaataacgc cccgtatcaa aaaattcatc
     5401 aatggcctgc acaaagactt gaaaaacttt ttttgcagaa ctcaagtaag aaaaatcatg
     5461 ctcatgacaa gccagacgat tttctttctg aatcggttct tgccagaaaa atcctagaaa
     5521 aattcctagt attacagcca caagaatgga acccagagct cgtaataggg cgacatggaa
     5581 ggagttgcca aaggcagaat aggtcgcaaa aagaacaatg ggattgataa caggtgctgt
     5641 cacaagaaaa ggaacggccg tgtaacttgg aacctttttt tccagaaaac gattgatgat
     5701 ggggacgatt ccacattcac aagaagggaa aaacataccg acgaaggtcc caaaaaagat
     5761 tctcccccaa cgatttcgag ggagaaaatg ataaaccttg tcaggtgtga tataaacttc
     5821 aatcagccct gagacaatgc ttcctatcag aacgaaggga agggcttcaa tgataatgga
     5881 gagaaaaatg gctccagttt gaagtacact agatgggagt tgttgaaaag cagtcatcta
     5941 gtttttcttt tctgctttgg cttttttctc tttgtcatca gggaaagtaa cttgtttcaa
     6001 atcagggagt ttagcaaact cttcaaacat cttgtccaag tcgtctcgtt ttgtaaattt
     6061 tacagccata ggtgtacctc gattctaaat tctacctcta ttatactatt attttgcgga
     6121 aaagggagtt ttttaatttg ttttcgatag ttgatactct tcgaaaatct cttcaaacca
     6181 cgtcagcttc gccttaccgt agtacggtta ctgacttcgt cagttctatc cacaacctca
     6241 aaacagtgtt ttgagctgac ttcgtcagtc ttatccacaa cctcaaaaca gtattttgag
     6301 cagcctacgg ctagcttcct agtttgcttt ttgattttta ttgagtatga aaaggattgg
     6361 agaaagcctt ccagcttgtg gtataataga tttatggata aaaaatatga aaaaatctct
     6421 caggatttgg gagtgacgtt aaagcaaatt gataccgttc taagtttgac agctgaaggg
     6481 gcgactattc cctttatcgc gcgttatcgc aaggacatga ctggtagtct ggatgaggtg
     6541 gcgattaagg ctattattga tttggataaa agtctgacaa atctcaatga ccgtaaggaa
     6601 gctgtcttag ctaagattca agaacaaggt aagttgacca aggaattgga agaagctatc
     6661 ttagttgccg aaaaattagc agacgttgaa gaactctatc ttccttataa ggaaaagcgt
     6721 cgtaccaagg caaccattgc ccgtgaagct ggactctttc ctcttgctcg cttgattttg
     6781 cagaatatag ttgacttaga gaaagaagct gaaaagttcg tctgtgaagg atttgcgact
     6841 ggcaaggaag ccttgaccgg tgcagttgat attttggtcg aagccttatc ggaagatgtg
     6901 accttgcgtt ctatgactta tcaggaagtg ctgagacact ctaaactcac ttctcaagcc
     6961 aaggatgaaa gtcttgatga aaagcaggtt tttcagattt attatgattt ttcagagaca
     7021 gttggaacta tgcaaggcta tcgtaccttg gctctcaatc gtggggagaa acttggtgtc
     7081 ttgaagatcg gttttgaaca tgcgacggac cgtattcttg ccttctttgc tactcgtttc
     7141 aaggtgaaaa atgcttatat tgatgaagtt gttcagcaat ccgttaagaa aaaggtcttg
     7201 cctgctattg agcgtcgtat tcggacagaa ttaactgaga aagctgaaga gggagctatc
     7261 caactttttt ctgacaatct gcgcaatctc ctcttggttg ctccactgaa agggcgcgtg
     7321 gttcttgggt ttgacccagc ctttcgtaca ggtgccaagc tagctgtcgt ggatgcaaca
     7381 ggaaaaatgc tgacaactca ggttatttat cctgttaaac cagcatcagc tcgtcaaatc
     7441 gaagaagcca agaaagattt agcagattta attggtcaat acggtgtaga gattattgcc
     7501 attggaaatg gaacggccag tcgtgaaagt gaagcttttg tagcggaagt tctgaaagat
     7561 ttccctgaag tcagctatgt tatcgttaat gaaagtggtg cttctgtcta ttctgccagc
     7621 gaacttgctc gtcaggagtt tccagacttg accgttgaaa aacgctctgc catttctatc
     7681 gcccgtcgtt tgcaagatcc tcttgcggaa ttggtcaaaa tcgatcctaa gtcaattggt
     7741 gtcggtcaat accaacacga tgtcagtcag aagaaactat ctgagagtct ggactttgtt
     7801 gtcgatacag tggttaacca agttggtgtc aatgtcaata cagctagccc agctcttctt
     7861 tcacacgtag ctggactcaa taaaaccatt tctgaaaata tcgtcaaata ccgtgaggaa
     7921 gagggaaaaa tcacttcacg ctcccaaatc aagaaagttc ctcgtttggg ggccaaggct
     7981 tttgaacagg ctgctggttt cctccgtatc cctgaaagta gcaatatcct tgataataca
     8041 ggagttcacc cagaaaatta cgctgccgtt aaggaactct tcaaatgctt ggacattaag
     8101 gatctgaatg aagaggccca aagtaaactc aagtcgcttt cagtcaagga aatggcgcaa
     8161 gagttagacc ttggtccaga aactcttaaa gatatcattg cagatcttct caaaccaggt
     8221 cgagatttcc gtgattcctt tgatgctcca gttctccgtc aagatgtcct agatatcaag
     8281 gacttagtgg ttggacaaaa gctagaagga gtggtgcgta atgttgttga tttcggtgct
     8341 tttgttgata tcggaattca tgaggacggt ctcatccata tttcccatat gagtcgcaag
     8401 tttatcaaac accctagtca agtggtggca gttggagatt tggtgagcgt ttgggttaag
     8461 aaaattgata ctgaacgtga aaaagttaat ctgtctctcc tagctccaaa tgaaactgac
     8521 tgattacgtc aagcaggttt cactagaaga cttcggcaga ccttttatcc atcatgtcca
     8581 gtggaatagg cgtctacgtt cgacaggtgg gcgatttttc cccaaagatg ggcatttgga
     8641 ttttaatccc aaggtttatc aggaactggg gttggacgtt tttaggaaaa ttgtccgaca
     8701 tgaactctgt cattatcacc tctattttca agggaaaggc tatcaacaca aggatcggga
     8761 ttttaaggaa ctgttgaaag cagtggatgg attacggttt gtaccatcct tgcccaatag
     8821 taactccaag ccaatcaagc tctatcgttg ccaatcctgc cagcaaactt atcagcgtaa
     8881 gcgtaggatt gatacccaac gctatcgctg tggactttgt cgaggaaagt tgctattagt
     8941 aaatcagcct gaggactgat gaaagccgag cctatccgtg atatactagt ctaacctagc
     9001 agaaagagga aatatcatga acagtaagtt ttataaaatg agacgaaatc gcatgatttc
     9061 aggagtttta gcaggtctgt cagacaagtg gaactttgat gttacccttg tacgttttct
     9121 gtttgccatt tttacagtcg caaactttgg acttggggtg attatctata tcatcctagc
     9181 ttctatcatg ccaaccaagg aagaaatcga agcagaaatg tacggaacag gcccacgtaa
     9241 acgcaaagaa gctcaagcca ttgacgataa tgaaggctgg ttttggtgag gttttacaaa
     9301 agatttggaa tacgcaaaaa gctttaaatc aatagtctaa actgcttgat ttaaagcttt
     9361 tttactttta tactcaataa aaatcaaagt gcaaactagg aagccagccg caggctgtaa
     9421 tttagtcggc aatgtgaagt tgatatagtt tgcactttga tttttgaata gtattaataa
     9481 tatttcgcca gcttcatcca caaactatag tggattggaa ctagaatagg acacctatac
     9541 ttctaaaaaa ttgttagaaa tcgatttgac tgtcctgatc gatttgtcct gttcttattt
     9601 cattttacta taaaagcagt aatttaaacg cagtttttta atctattttt gctgttgaga
     9661 caatacattt ttggaaaaat ggtggatgct gataacaact gataaccagc aaataacata
     9721 agcagtgccg gtaaattctg taccgataaa gtgtgtgtgt tcaactaaga gctgaccgat
     9781 gaatggagag agcagataga gaagtccgat gagtatatgt tctttgtgtt tcattaaagc
     9841 gcaccttctt tccttatagg ttgaacgact tgcaagtgtt aaattgaatg gtatgttatc
     9901 taggtaacct tactaaaatg ttagttcccg cttcctcctt ttcaaagtaa gccttttcac
     9961 acttatattt tacaacttta aaaataggaa atcaaatcat tttctaagta attttgctta
    10021 tatttcaccc aatcttacaa aaatgtaaga ttaaagtctc ttttgtaagg ttaggttatg
    10081 gcaagcggtc tttttttgat gtaaactaga ctcataaaga acaaaggagt aacatcatga
    10141 aacaaatctt acataagaaa actagaaaac caagtcacaa agaaattgag cgcgttcagc
    10201 tgggatgcac tatgatgcaa gctacatttc atttgatggg atattaagaa aggagattct
    10261 catgacactt ttagatgtaa aacacgttca aaaaatttat aaaacacgtt ttcagggcaa
    10321 ccaagtagaa gccctcaagg atattcactt taccgtcgaa aagggtgact acgttgccat
    10381 catgggtgag tctggttctg gtaaatcaac tcttctcaat attctagcta tgctggataa
    10441 accaagtcgt ggtcaggttt acttgaatgg aactgacacc gcaaccatta aaaattcaca
    10501 ggcctctagc ttccgtcgtg aaaagttggg ctttgtcttc caagacttta acttgctaga
    10561 tactctatct gtaaaggaca atatcttgct tccgcttgtc ttgtcaagaa gacctattac
    10621 agagatgatg aagaaattgg tggtgacagc tgagaatctg ggaataaacc aattacaaga
    10681 gaagtaccct tacgagattt ctggtggtca gaaacagcgt gtagcagtag ccagcgccat
    10741 catcacagaa cctgaaattc tccttgcgga cgaaccgaca ggagctcttg actccaagtc
    10801 atctgcagcc ttacttgatg tctttgatga aatcaatgag cgcggccaaa ccattctcat
    10861 ggtaacccac tcaacagcag cagctagcag agctaaacgt gtactcttta tcaaagacgg
    10921 cattctttac aatcaaatct accgtggaga gaagacagaa cgtcagatgt tccaagaaat
    10981 ctctgatacc ttgactgtca tggcaagcga ggtgaattag tatgtttcga ttaaccaata
    11041 agttagcggt atcgaacttg attaaaaacc gcaaactcta ctatcctttt gcgctggctg
    11101 ttctcttggc agtcactgtc acctatctct tttactctct aaccttcaat cctaagattg
    11161 cggaaatccg tggaggaaca accattcagg ctacacttgg atttggtatg tttgtcgtca
    11221 cccttgcgtc agccattatc gttctctatg ccaatagttt tgtcatgaag aaccgttcca
    11281 aggaactagg aatttatggc atgttgggct tggagaagcg tcatcttatc agtatgacct
    11341 ttaaggagtt agtggtattt gggattctaa ctgttggagc gggtatcggt attggagcct
    11401 tgtttgacaa gttgattttc gctttcctac tcaaactgat gaaattgaag gtggaactgg
    11461 tcgctacctt ccagatgaaa gttgtcatta cagtacttct tgtcttcggt ttgattttcc
    11521 taggcctcat gttcctgaat gcccttcgaa tcgcccgtat gaatgccctc cagctctcac
    11581 gtgagaaagc tagcggagag aaaaaaggtc gcttccttcc tctccaaact attcttggtt
    11641 ccataagttt agggattgga tattatcttg cccttacggt aaaagatcct cttacagcct
    11701 taacaacctt cttcctagct gttttactgg ttatctttgg tacttatctt ttgttcaatg
    11761 cagggattac cgttttcctt caaatcttaa agaaaaataa gaaatactat taccaaccta
    11821 ataatctcat atctgtttct aacttgattt tccgtatgaa gaaaaatgca gttggactag
    11881 caactatcgc tattttgtca acaatggttt tggtaaccat gtcagcagcg acaagcattt
    11941 tcaattccgc agaatccttt aaaaaagttc taaatcctca tgattttggg gtttcagggc
    12001 aaaatgttga aaaagaagat ttggacaaac tcttgagcca gtttgcaagt gacaaaggtt
    12061 ataagattaa agagaaagaa gtgcttcgtt acagtaactt tggtattgca aatcaagaag
    12121 gaaccaagtt aactattttt gaaaaaggac aaaaccgtgt ccaaccaaaa acagttttca
    12181 tggtatttga ccaaaaagat tatgaaaata tgactggtca aaaactgtct ctatcaggaa
    12241 atgaggtcgg tctctttgcc aaaaatgacg gactgaaagg acagaaagct ctaactctaa
    12301 atgatcatca attttctgtc aaagaagaat ttaataaaga tttcattgtc aaccatgttc
    12361 caaataagtt taatatcttg actactgatt acaattacct tgttgttcct gatttacaag
    12421 cctttttgga tcaattccca gattcggcta tctataatca gttttacggt ggtatgaatg
    12481 tagatgccag cgaagaagaa caactcaagg tcgctgagga gtatgaaaac tacctcaatc
    12541 aatttaatgc tcaattagac acagaaggta gctatgttta tggtagcact ctagcagatg
    12601 ctagtgctca gatgagtgcc ctctttggtg gtgtcttctt tatcggtatt ttcctatcca
    12661 ttatctttat ggtcggaact gttctggtca tctactacaa acaaatttct gaaggctacg
    12721 aagaccgtga acgctttatt atcttgcaga aagtcggttt ggaccaaaag caaatcaagc
    12781 aaaccatcaa caaacaggtt ttaactgttt tcttccttcc tttgctcttt gccttcctac
    12841 atctagcctt tgcctaccat atgcttagcc tgattttaaa agtgattggt gtactggata
    12901 cgactatgat gttgattgtg accttgtcta tctgcgctat cttcctcatc gcctatgtgc
    12961 tgatttttat gattacttca agaagttatc gcaagattgt gcaaatgtaa aaaagatacc
    13021 tagacttcaa aatcgaggta tttcttgtat tctaaatgct gaaaagttgt tcgagcagga
    13081 aggtaactcc catggtcaag agaccaatag caaggttccg aatcatagct gttttggttg
    13141 gggcttttcc aagtctagca cttgtgtaac cagtgagaag aagggccaca ccgacaataa
    13201 ggacggtagc agggatgcgg taatcacttg gaaaaatggt cactgacagc attggaggca
    13261 aacttctaag gaaaaaggca acgaagctag aaatggcagc gtgccaagga ttggtaaatt
    13321 cttcatactc aatcccatat ttttcctcta ccagagcctt gagtggattt ttaagaaaga
    13381 tcttattagt caagagttgg gcagaagttt tgaattctcc attttggata taagaagcat
    13441 agagggattt tttggctagt tccctatctt ggtctagcaa gagtttttct cgcgaaacgg
    13501 cagcttcctc ggtatctttt ggagttgaaa cggatacata ttctccacca gccattgaaa
    13561 aggcaccagc taagatagcc gcaaaacctg ataaaaagat aatccagata ttgctcgtgg
    13621 cactggcaac tccgataacc acaccagcaa tggaaataat tccatcgtta gcatcaagaa
    13681 cacccgcacg caggatattt aaacgacctg caaaatttga atcaatttcg tgatttgttt
    13741 ctgacgctaa atttcaagtt caagttagcc atccagaagt cttctctggg tgacttgtag
    13801 tccaagcatt ttttaggata gttgttaatc cacttttcga tgaatgcgac ttctttggga
    13861 gtcattttct tgattccctt aggtaaccat ctacgaatga gcctgttgtg attctcatta
    13921 gttccccttt cccaagaggc ataggggtgc gcataataga tgtgctcctc agaaaataca
    13981 tcaaacaagc gattgaattc cgttccatta tctgccgtga tggaaagaat cttgtgttgt
    14041 tttaagatga gttttagagc ctgattgacc acatcagcac ttttatttgg aatcaatcgg
    14101 atgatctgat gtctactctt tcgatcagtc aagacaagca aacagtagtt tttcgctctc
    14161 gtaagtagaa ccgtatcaat ctcataatgc ccattctcca agcgaagatt gatagcttca
    14221 gaccgctgtt cgatggattg accagcaggt ttaaagttgg tgctagcctg tttcttaagc
    14281 gcttttcctt ttctagggta aagcagatcc tgtttgctta accccaattt tccatgatga
    14341 atccaatagt aaatggttga aattcccacg ttaacccctt taaccatcac catcatttca
    14401 ggcgaaaatt tttggttatg atagtggaga atcttttcct ttagttcctt ggtcacgctt
    14461 gatttcctga ccgagcgctt gcgattgttt tcataagact gttgagcata gtcggcagaa
    14521 taaacctctt tgaagcgccc ttttccaaga cattgtcgga ctgtcccacg cttgatttca
    14581 gtgtggatag tttgaggaac ttttccaagc agagaggcaa tttctctatt tgatttccct
    14641 tcttttttcc atctttcgat taagcgacgg ctatcgattg tcaaatgttt ggcttttgta
    14701 gtataattgt cttgcatctc tgtgcctttc ttgtgtttgt ggttgaacaa caagtataac
    14761 acagaggtgt tttcttatgc ctacaagagc tatcagctag ttgaaccatc taatttttag
    14821 gagggctggg tggctaactt cattatagaa ctttcattta cgaacatata gtaaaatgaa
    14881 acaagaacag aacaaatcga tcaggacagt aaaatctatt tctaataatg ttttagaagc
    14941 agaagtgtac tattctagtt tcaatctact atatttttgt tttttatcaa aaaatacttt
    15001 acaagttctt aaaaacatga tatagtaata aagcttagaa aatgagatga tgttttctag
    15061 caaatataaa cccgagtaaa aaatgcctac ggacaggcag ggttgaatgc cgaagcgtgg
    15121 ttgaaaagcc acattattga tagggttaaa agcctacttt tataagttga tgttaggaca
    15181 cttgtcctaa ttcataaatt tttagtgtgg tgaaagcaca cgtcatcttg tgaaacgatc
    15241 aataaagtac gtaatatttg ctactagaga gttaggaaac atcgggaaca gacatactca
    15301 acagaaacca aaataaacac gtcagaagat tgcagagcag gtgaaaacct gctctttttt
    15361 catgagtcaa cctttagttc cttagttttc ataaggtcct aaaaatattg aaaggagtat
    15421 gttttgaaag agttagatca aaaccaagcc ccaatttatg aagccttggt gaagttacgc
    15481 aagaaaagga ttgttccctt tgatgttcca ggtcacaagc gtggacgggg aaatccagaa
    15541 cttgtcgaac tcttaggaga aaaatgtgta ggcattgatg tcaattcgat gaaacccttg
    15601 gataatttag gccatcctat ttcgattatt cgtgatgcag aggagctggc tgcagatgct
    15661 tttggagcta gccatgcctt tctaatgatt ggtggaacaa cttcatcggt gcagactatg
    15721 attctggcaa cctgcaaggc aggagataag attattctgc cacgaaatgt ccataaatct
    15781 gctatcaatg cgttggttct atgtggtgcc attcccatct atatcgagat gagtgtagat
    15841 cctaagattg gtatcgcttt aggtcttgaa aatgaccgag tagcacaggc cataaaggac
    15901 catccagatg ctaaggctat cctaatcaac aatcctactt actacggcat ctgttcagac
    15961 ctaaaggggt tgacagaaat ggctcatgaa gctggcatga tggttttagt agatgaagcc
    16021 catggagcgc atttgcattt cactggtaaa cttccaattt ctgctatgga tgcaggagct
    16081 gatatggcag cagtttccat gcataagtct ggtgggagtt tgacacaaag ttcgcttctt
    16141 ttaatcgggg agcagatgaa tcccgagtac gttcgtcaga ttataaacct gacccagtct
    16201 acatctgcct cttacttatt gatggctagt ttggatattt cacgtcgcaa cttggccctt
    16261 cgtggtaaag agtcgtttga ggaagtcatt gagctatccg agtacgctcg tcatgaaatc
    16321 aatgccattg gcggttacta tgcttactca aaagagttaa tagatggtgt gtcggtctgt
    16381 gattttgatg taaccaagtt gtcagtttac actcagggaa taggcttaac aggtatcgag
    16441 gtttatgacc tcttgcgaga cgaatacgac attcagatcg agtttggtga tatcggcaat
    16501 atcttggcct atatttccat cggcgaccgc atccaagaca tcgagcgctt ggttggtgct
    16561 ctggctgata ttaagagact ctattcacga gatgggaagg acttaatagc tggagaatat
    16621 attcagcccg agttggtgct gtctccacaa gaagccttct attcagagag aaaaagtttg
    16681 accttagatg agtctgttgg acaggtctgt ggagaatttg tcatgtgcta tcctccaggg
    16741 attcctatct tggctcctgg tgaacgcatt acacgagaaa ttgtagacta tatccaattc
    16801 gccaaggaac gtggttgctc cctccaaggg acggaagatc cagaggtcaa tcatatcaac
    16861 gttattaaga gaaagacaaa ctataagaaa agtcaatagt tttatctaaa ctatttctta
    16921 tttcaatttg atgatttggc gatgatttta gagcacggca aaaagccctt gaattagaag
    16981 cggtcaatcg cttaatttct atcagcttat caaatcctgc ctcaatcctt ttctgaggat
    17041 tagggtagcg tgtcaagagt tggtaggtat attctgaatg ctttccaacg attttatcca
    17101 actcaggaaa gatgatatca agacaacgag tgtattgtac tttccaatca gactgttttt
    17161 cttgagacga tgaatatgtc tagccagtat ttttagttct acttgccgat tatcgtgttg
    17221 aaattgttca cgattggggt cagaaagaag tttaagagcg atgccatgag cgtctttctt
    17281 atccgtttta gtcttgcgaa gtgataatga tttggcaaat tccttgatga gcaaaggatt
    17341 gtaggtgtaa actttatatc cttgttcatg caggaagttc agtagattaa aggcataatg
    17401 tccagtatct tcaagagcga tgagacagtc ttggttga
//
LOCUS       DAVHKZ010000041        17033 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000041 DAVHKZ010000000
VERSION     DAVHKZ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17033
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.041"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(32..262)
                     /locus_tag="VVO74_001755"
     CDS             complement(32..262)
                     /locus_tag="VVO74_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695745.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(280..921)
                     /locus_tag="VVO74_001756"
     CDS             complement(280..921)
                     /locus_tag="VVO74_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5695746.1"
                     /translation="MKLLKNLGWILLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(933..1667)
                     /locus_tag="VVO74_001757"
     CDS             complement(933..1667)
                     /locus_tag="VVO74_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU5695747.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(1670..1867)
                     /locus_tag="VVO74_001758"
     CDS             complement(1670..1867)
                     /locus_tag="VVO74_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695748.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            complement(1867..2073)
                     /locus_tag="VVO74_001759"
     CDS             complement(1867..2073)
                     /locus_tag="VVO74_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5695749.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2083..2397)
                     /locus_tag="VVO74_001760"
     CDS             complement(2083..2397)
                     /locus_tag="VVO74_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695750.1"
                     /translation="MWVLVFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDKKGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(2664..2741)
                     /locus_tag="VVO74_001761"
                     /pseudo
     CDS             complement(2664..2741)
                     /locus_tag="VVO74_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(2738..4027)
                     /locus_tag="VVO74_001762"
     CDS             complement(2738..4027)
                     /locus_tag="VVO74_001762"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU5695751.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(4105..5352)
                     /locus_tag="VVO74_001763"
     CDS             complement(4105..5352)
                     /locus_tag="VVO74_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEU5695752.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNAYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLDLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(5543..6394)
                     /gene="rgg"
                     /locus_tag="VVO74_001764"
     CDS             complement(5543..6394)
                     /gene="rgg"
                     /locus_tag="VVO74_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEU5695753.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELLV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            6518..6859
                     /locus_tag="VVO74_001765"
     CDS             6518..6859
                     /locus_tag="VVO74_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU5695754.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIEDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            6917..6997
                     /locus_tag="VVO74_001766"
                     /pseudo
     CDS             6917..6997
                     /locus_tag="VVO74_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(7113..8816)
                     /gene="ilvD"
                     /locus_tag="VVO74_001767"
     CDS             complement(7113..8816)
                     /gene="ilvD"
                     /locus_tag="VVO74_001767"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU5695755.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIIDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(9049..9981)
                     /locus_tag="VVO74_001768"
     CDS             complement(9049..9981)
                     /locus_tag="VVO74_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU5695756.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     NFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPEAVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(9978..10835)
                     /locus_tag="VVO74_001769"
     CDS             complement(9978..10835)
                     /locus_tag="VVO74_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU5695757.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(10839..12185)
                     /locus_tag="VVO74_001770"
     CDS             complement(10839..12185)
                     /locus_tag="VVO74_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU5695758.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(12198..12482)
                     /locus_tag="VVO74_001771"
     CDS             complement(12198..12482)
                     /locus_tag="VVO74_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU5695759.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(12486..14516)
                     /locus_tag="VVO74_001772"
     CDS             complement(12486..14516)
                     /locus_tag="VVO74_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU5695760.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            14707..15714
                     /locus_tag="VVO74_001773"
     CDS             14707..15714
                     /locus_tag="VVO74_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU5695761.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGVFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            15717..15917
                     /locus_tag="VVO74_001774"
     CDS             15717..15917
                     /locus_tag="VVO74_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU5695762.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            16069..16251
                     /gene="rpmF"
                     /locus_tag="VVO74_001775"
     CDS             16069..16251
                     /gene="rpmF"
                     /locus_tag="VVO74_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU5695763.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            16267..16416
                     /gene="rpmG"
                     /locus_tag="VVO74_001776"
     CDS             16267..16416
                     /gene="rpmG"
                     /locus_tag="VVO74_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU5695764.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(16896..>17033)
                     /locus_tag="VVO74_001777"
     CDS             complement(16896..>17033)
                     /locus_tag="VVO74_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695765.1"
                     /translation="ESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWV
                     G"
BASE COUNT         5516 a         3587 c         2914 g         5016 t
ORIGIN      
        1 acaaaaatcc gatgaacttc accggactct tttattttga atttttgcct gctttacgct
       61 tttcagcgat ttcggctgcc tttcgaggca agacaatttc cgttatgtaa gccgtcccaa
      121 aacgcagtac acctgcaata ggagcaaaga caactgctag atagttatag aagaaatcgc
      181 ctttgaaggc ataagctagc gctccaatga tgaaaaatag aacgactgcc tgaatcactg
      241 ctaataaaat tactcgtttc atgtgacctc ctgactctat tatagcatga gaatcatcaa
      301 aaagccgact aaattattca aagcgtgaag agaaatactg tagaccagac cttttctgct
      361 aatgtaagcc aaacccaaac taaaaccaag gctaaaatag acaaaaaatt gttgcacatc
      421 acctggaaaa tgaatcaagg caaatagaag actagatacc agaagaaaaa tcagggttcg
      481 tttactattg tcctgcttag gaaagagata gcgtgctaac atccctctaa aaacaatctc
      541 ttccgtcaaa ggagcaaaaa taaccacagc aaagaatgag aaaagtggtt gagacaaggt
      601 caagtctgtc gctatttgct gatttactga aggatcatct ggcaagaaga attgaacgac
      661 cagagataag aaccaaacca aggcaggaag ccaaataaat cggttaaagc cgctcttctc
      721 aatataaaca ggagctttct gataccattt gtaaatgccg tacacatata ctccagccaa
      781 gaccacatag agtagagtaa cagcataggg tgaagcgcct aaagcaagcg acgcagtcgc
      841 gagcccctga ataaagccat agataaagaa aaaggataga agggctagaa gaatccagcc
      901 aaggttttta agtaatttca tagataactc ctttatttga aataacgttt taccataggt
      961 aactgcatca cattgatata aacatggatg gctcctacaa gcaagaaagc tagtaactga
     1021 atctctcctg tcaagaaaga aatgataata agaaaaatat ataaggctgg taagacatat
     1081 tggtgtaatt ggaataaaat tcgaaaactc tgttccaaat tagcctgacg ctccccttca
     1141 tcataagaat ttatatagtt caagacatcc tttggtgtag cgaaaaattc caaatcaaac
     1201 tgacgaacaa tcgcaatggt tttaaaaaga gatttttgag cgactaagaa taccacaaag
     1261 agtaagaaag aaaggaaaaa tgtttgaggg tttgtatgca atataatcac ctcacttaat
     1321 gaaataaaaa tagccaatgg aatcgctaca cctgtaatat taaaagcaat ggttccaaac
     1381 tcaagattcc gatacatttg cacataatag gtttcattca gatcgtcatc catttcctct
     1441 tgatacaagg aatgaaattt tctgcttttc tttaagaaat tgaaagtcaa aaacatacta
     1501 atgaaaccta tcagtaaaca aatagctgat atccatggca tcaaggcttt tacatctaaa
     1561 ataatttcgt gggattcgac acgtgcctta aacatcccta caaacatgcc caagaacccc
     1621 cccaagacaa tagacatcaa aaataacaat ctacgtttct ttttcatatt cattctcctt
     1681 tttcacttgc tagatttttg gatttctttt caatccattc agttactggg atgagagcaa
     1741 agtagaccca aacaaattgg tcgctttgat agggattaaa ccagcttagg tccatcccaa
     1801 tcagtagaaa tacgctgact aataaagcta tgaccactac ataataaatc actttatact
     1861 tgttcatcac tcgtcctcct ccaaacgaaa taccgattcg actgtttcgt tgaaaatttg
     1921 agatattttc agggcaatga taatggatgg ggtgtactca tcccgttcta gtaggctaat
     1981 ggtctgtctg gaaacccctg ccagtttggc taggtcggtt tgattgagac catcgcgagc
     2041 tcgaagctct tttagacgat tttttagttg catgttacac acctactctc cgtcaaattc
     2101 aacggtttgg atatcttcaa tacgttgcaa cttgaatttt tctttcccct ttttatcaac
     2161 actacgtagt ttgacccatt cctcgtcaac atccacaact tcccagttat ctggcccaat
     2221 atacactccc gttataattg gttcctttcc aatcatttct tgcaataatc tcgacatttc
     2281 tgcgtttcct ttctcttttc gctcaagttt tttgatttta ttctctagtt tcttgatttt
     2341 tttagaatta ttagaataaa agaaaatcat aaatagtata aatactagta cccacattat
     2401 aactcctttc tgcttcctat ttcttaactt gaattcattg taacacatct ttttcttttt
     2461 gacaattata gttgtcaaaa agtttatgat ttttgtcatt ttgcaaaaga aaaaggtcag
     2521 gagtaagttc ctgaccactt tatctatcat taatactctt ctaaaatctc ttcaaaccac
     2581 gtcagcttca ccttgccgta ggtatagtta ctgacttcgt cagtttcatc tacaacctca
     2641 aaaccatgtt ttgagctgac ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag
     2701 caacctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa aatcctagtt
     2761 tttcaaagat ttctgagaag ttttggctga ttgtctcaag tgacacttgc acttcttctc
     2821 gggtttggtt gttcttgacc gtcacttgtc cgctttcgac ttcgctctct cctagggtga
     2881 tgagggtctt agccgcaaag acatctgctg acttgaactg agctttgagc ttacggttga
     2941 ggtaatcacg ctctgctttg aaaccttgtt ggcgaagagc ttggactagt tctagggctt
     3001 tgacatttgc tccatcaccc aagactgcga tatagacatc tagggcgttt tcgataggga
     3061 gggccacgcc ttgtttttca aggatgagaa gcaggcgctc tacaccaagc ccaaaaccaa
     3121 atccagcagt ttcagggcct ccaaagtaag caaccaaacc atcgtagcga ccacccgcac
     3181 agactgtcaa gtcattgccc tcaatctctg tgataaactc gaaaatggtg tggttgtagt
     3241 agtccagacc acgcaccata ttggtatcga tgatgtaatc tactccaaga ttttccaaca
     3301 tctgacgcac agcatcaaaa tgagtttggc tttcttcatc aagaaagtcc aagatagacg
     3361 gcgcattctc tactgccacc ttgtcttctt tttccttaga gtccaagaca cgaagaggat
     3421 tttcctccaa gcgacgttgg ctatccttag acaaggtctc cttgagcggt gtcaaatagt
     3481 caatcaaggc ttggcggtag gctgcacggc tctcaggatt tccaagagtg ttgaggtgca
     3541 atttgacacc ttgaataccg atttccttca aaaaatgggc tgccataacg attgtttcca
     3601 catcggtagc tggattgcta gagccaaaac actcaacacc aatctggtgg aattggcgca
     3661 agcgccctgc ctgtggacgc tcataacgga acataggtcc catgtagtag aacttgcttg
     3721 gcttttgcac ttctggggcg aagagtttat tttccacata ggaacggaca acgggcgcag
     3781 ttccttctgg acggagggta atatggcggt cacccttgtc atagaaatcg tacatttcct
     3841 tggttacgat atccgttgta tctccgacag agcggctgat aacctcgtaa tgctcgaaaa
     3901 taggcgtacg cacttctgcg tagttgtagc gcttgaaaat ctcacgggca aagccctcaa
     3961 cgtactgcca cttagcagac tcagcaggta aaatatcctg cgttcctttt ggtttttgta
     4021 atttcatagg gaatcctctt taaacttaat agtcttattt taccataaat agagggatta
     4081 aaacagtgag aaaaaaatta ggatttagat atcatttttg agattaagaa ttgtcaaaaa
     4141 aatagctagc aaggaaagac caacaaatag catccaagtc aactgtatat tccatacggc
     4201 tactagtgaa aaacaagctg ttcccacagg tatggataag gtaaacaata gatctaaaaa
     4261 attactagta cgagctagaa cctctggagc tagatttttc atgagcatgg cactaatctt
     4321 tggttgaact ttaccagaca catacagagt aaagaagaga aatagcaaac caagcacgac
     4381 ttgattgaat aaattagcca aaccaactag actaagtcct acagtcgccc acatcatcaa
     4441 tctaggcaag gactgcttcc caaaataagc attgcccgta aggctactga tgatgattgc
     4501 tactaaaaca cagaattgat tgataaatag tgcctctgta taagaaaaat tcaagagaga
     4561 atggctcaaa aagaagatat tataaattcc acccaaagcg ccacccaagg aattaataag
     4621 caagacagca aagagcataa aaccaaagtt tttctgccca cttttaagaa aaacgagacg
     4681 taaatttcgg taaattgtta ggaactggtc tttgatagaa agcttctcat tttttaagtt
     4741 ttcaccatca gcagatgaca ttgacaggct caatttgctt tttcctaaaa agaggatagt
     4801 ggctgatact aggaaaaagc aggcattgat tcccgcaacg agagaaaaat tgttgaccga
     4861 tagagctaag agccagactc cgaaagcttg accaccaata gctgaaatat aggtgatgaa
     4921 ctgtgaaaaa gaataagcct ccatcagatc atcttcagct actttttcct taataagagg
     4981 catacgcagg ccacctgcaa aatcactgat gatatcacta atgacattga tcaaacacag
     5041 gctagaaaag gcaaagagac tagcttgctg aacaactagg gctgctagaa aaaatagaac
     5101 cgcctgaaac aaaccgctat agaccatcca tttgaccttg tccctcgtgt aatctgcccg
     5161 aatccctgca aaaactgtaa agaaggtcgg aagaatcatg acaatattcg ccatagcaac
     5221 agcaaaagat gcttgtgaca aggtcgatgc atagacgata aagaccaggt tgaaaatcga
     5281 agcaccaaaa gcattgaaga agcgtgataa agtcaaaatt ctataagctg gatttctaaa
     5341 caatagtttc atagataatc tccctccttg ttctaagttc tacatcaaga atagctttag
     5401 tatagcactt atgaatttgc gaaacgattc ttttgaatat atgcaacaaa caaaatgagc
     5461 aaaaaaacga tagaactttt gtaatgacct gagagagggt aacagttcta tcgcttcaaa
     5521 ttttttcttg gtttgcagat actcaacatt cggtcgtatt tctatagtat tcggcagatt
     5581 tattacagcc aagcatctca aaaatacgga cagcatcctc catctttttc tggccttcct
     5641 tgactctacc ttgcttgcta tcaaggagac cttctgccca cagataaaca attcggaaat
     5701 aggtctcatt ttccttgtag aaatgctctt cgataacacg tttaaaataa taggcattgg
     5761 taaattcttc acactcaata ctagctaaaa agccattcaa tagtatagta tgaaaaaggt
     5821 ttcgattgcc agacatttcc attagaaaat cagatttacg taccatttct cgtacatatc
     5881 tagtaaaaag agaaacagat aaaaatggag aactgactga aaataaattg agttcataga
     5941 ttccccagat ctcggtagaa aacaaataat catgaaggac ttttccttcc tctgctgtta
     6001 actctaccct ttcatctatg ctcttcatat aagacttgat aataatggca tttagaatat
     6061 gtttctgttt gttgtgagaa tgggcatgct tttgatactc cctgcgatat aagtcctcaa
     6121 gaggtgctat attctttggt tccaagacat ctgtaatttc ttttctcaac tcagaatctg
     6181 tatcatactg gaaacctctc gccagaaaga ggatctcctc cacactggca gatatatttt
     6241 ccagagcaaa tagaaacttt tccaccaaaa gctcactctg acctgtttca aaacgggaca
     6301 acatagacgg cgaaaattgt cctccggttg cttgtctcag tgagatattt cttgactctc
     6361 gtaattgtct aaagactttt ccaatctgct ccatagactt ccccttgatt ccgtattttc
     6421 ttcattttat catatttttc agaaaattca tcaaaaactt gccaaattgt cagaattatg
     6481 agaaaataga ggatatttat cacgtggagg gactgctatg agagacgata tcaaaatcaa
     6541 tgaccgtgct ttggccttgc aagaccaaat tatcgaaaaa ctagagaaag tttttgatac
     6601 agatgtggaa ttggatgttt acaatctagg tctgatttat gaaatcaatc tggatgaaac
     6661 ggggctctgc aagattgtca tgaccttcac cgatactgcc tgtgattgcg ccgaaagcct
     6721 gcctattgaa atcgtggcag gtctgaaaca aatcgagggt atcgaagata tcaaggttga
     6781 agttacctgg tcgcctgctt ggaaaatcac acgaatcagt cgctatggcc gtattgccct
     6841 tggactacca cctcgttaag caggccaatc acttttaaag atgaaaaaag caagccgaaa
     6901 atggcttgct ttttgatact caatgaaaat caaagggcaa actagaaaac tagccgcagg
     6961 ttgctcaaaa cactgttttg aagttatgga tagaactgac gaagtcagct caaaatactg
     7021 ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat acctacggca aggcgacgtt
     7081 gacgtgattt gaagagattt tcgagtatga gtttattttt tacctgactt gtccatattc
     7141 cagaagtctg tcacggctcc gcgtgaagca gatgatacga tgtgggcata tttaccgagg
     7201 acaccacggc tgtaaagtgg tggcaaggtt gtttctgcct tgcgtttttc aagttcttct
     7261 tcggatacgg ccatggaaat ttctttggta tcttggtcaa ccgtaacgat atcgccggta
     7321 cggagatagg caattggtcc accatcctga gcttcaggag cgatatgtcc aacaaccaga
     7381 ccataagtac caccagagaa acgtccgtcc gtcaagaggg ccaccttatc tccctgacct
     7441 ttaccaacaa tcattgaaga aagtgacagc atctcaggca taccaggacc acctttaggt
     7501 ccaacaaaac gaacaacgac tacatcgcca tcaatgattt catctgtcag gacggcctga
     7561 atcgcatctt cttctgagtc aaagacctta gctggcccaa cgtgacgacg cactttaaca
     7621 cctgatacct tggcaactgc accgtcagga gcaaggttcc cgttcaagat gataagcgga
     7681 ccatccgcac gttttggatt ttcaagtggc atgataactt tttggcctgg agtcaagtct
     7741 gcaaagtcag ccaagttttc agctacagtc ttaccagtac atgtgatgcg atctccgtga
     7801 aggaaaccat ttgccaacaa gtacttcata accgcaggga caccaccgac ttcgtagagg
     7861 tcttggaaga catactgacc agatggtttc aagtcggcca agtgaggcac acgttcttga
     7921 atcgtattga agtcctcaag tgacaagtca acatttgcgg catgggcaat ggcgagcaag
     7981 tgaagagtgg cgtttgtaga accaccgaga gccatcgtta cagtaatagc atcttcaaag
     8041 gcttcacgag tcaagatatc tgatggtttg agaccaagtt ccaacatctt aacaacagca
     8101 cgtcctgctg cttcgatatc ttctttctta tcagctgatt cagctgggtg agaggatgac
     8161 cctggcaaac tcatccctag aacttcgata gcagttgcca tggtattagc agtatacata
     8221 ccaccacaac caccagggcc agggcaggca ttacattcaa gacgtttcac gtcctcagct
     8281 gtcatgtcac cgtggttcca ttttccgata ccttcaaaga cagaaaccaa gtcgatatct
     8341 ttaccatcaa gatttcccgg tgcaatagtt ccaccatagg cgaaaatagc tgggatatcc
     8401 atattagcaa tagcaatcat agatccaggc atgttcttgt cacagccacc gatagcgacg
     8461 aaggcatcca cgttgtgacc actcatagcc gcctcgatgg agtccgcgat gatgtcacga
     8521 gatgttagag agaaacgcat accaggcgtt cccatagcga tcccgtccgc tacggtaatg
     8581 gttccaaact gtacaggcca agcgcctgca gatttgacac cttctttagc cagtttcccg
     8641 aaatcatgca agtgaatgtt acatggtgta ttttccgccc aagtcgaaat cactcccaca
     8701 atcgatgttt caaagtcctt atctgtcata ccagtcgcac gaagcatagc acggttaggt
     8761 gatttaacca tgctgtcata aatgctactg cggtgacgtt tatctaattc agtcatctta
     8821 tccctcccat ttcagttttt actattatag cacaatttaa aggcaatgaa cagaataaaa
     8881 ttcttgaatt ttcagaaaat tctatacgca tgtgaaatat ttaaaattaa aaacaacaaa
     8941 gcggattagt gcactttctg atgaccagaa tatgcttttt aatccgcttt ctttaaataa
     9001 cgtactgtaa tttttacaga aattctttca gataagtgta tttaacatct atcttgcatt
     9061 ataaatttct agaaccttct cttttatatt cgattcactc aaaccatact cattaagaag
     9121 ataatccatt ttccctactt gaccgaatct ttcttgaaca cccatccgat gaatttttgt
     9181 tattccatca tcagagaata attcacataa agcactgcca attccaccta tctgattgtg
     9241 gttttctaca gtaaatatag tttttccact taacattgtt tttatctgtt ctggtatcgg
     9301 tttgattcta aataaatcta tcacacctac tgaataacct aatttagaca gttcatctgc
     9361 aactcgaata cttggagcaa ccattatgcc agaagcaacg attacaagat cttcaccatg
     9421 tcttaactca atgtagccct tagaaaaatc ttctccacct tgatatacag cctctggagc
     9481 ttttctaatt gttcgaatat attttagtcc ttttaagtct aatgtctgat tcaatatttc
     9541 acgaaattgg atatcatcag ttgcttcaaa aatgattgat ttaggaatta aacgtaacaa
     9601 tccaatttct tcaaatggca tatgtgtccc accattcatt tctgcagtta ctcctgcatc
     9661 tgatccaatc acagtggcat ccaattgtgc gtatccaaga gaaataaata attgatcaaa
     9721 tactcttcgt gaagcaaaag gaccaaatgt atgaagataa ggtctaaacc cctgaataga
     9781 caagcctgct gcaaggccga ccatttctgc ttccataatc ccaacattca cataacggtc
     9841 tccaaagttc ttttcaagat tattagtagc catcgaactt gacaaatcgg cttctaagac
     9901 tactatatca gaataacttt gattagcctc taaaaggaag tctctatata catgccgtaa
     9961 ttctttcgta cttctcatca ttctgtttcc tccaattcct gacttaatct ttctacaact
    10021 gaagttaaca tttgtttctc ctctacagta gggcgaagat gatgattgga tttcatttct
    10081 tccagctctt gaaccccttg acctttaata gtatctaata caatgcactt aggtgatgaa
    10141 ttatttgact gttttaattg gacaatccct tcataaattt ctctaatatc tgaacccttg
    10201 accctaatgg attcaaatcc aaatgctgaa aatttttcta cgaaatcacc tggattacaa
    10261 atatcctttg taaaaccatc taattgtttt ttgttatcat caacaaatac aattaagttg
    10321 gataactgtt gatgagaagc aaactgtata gcctcccaac attgtccctc atttaactca
    10381 ccatctccaa caatagcata agtataaaag ggactctttc ttattctctg accatatgca
    10441 agtccagttg caacactaat tccttgtcct aaagagcccg ttgtcatatc tatgcctggc
    10501 gttagatttc tatcaggatg agacggtaat ttggttccat ttgtatttaa agaatataag
    10561 aattctttgt caaagaaacc attcaaatag agtgtactgt atagagctgg tcctccatga
    10621 ccttttgata atatgaaata atctctatct cgtgctgcaa atatttctgg agtcattggc
    10681 attatttcac cataaagcac tgctaaaact tctacgatag acagacttcc tccgtaatgt
    10741 ccgaatccaa gatgattcaa tgttctaaga gtatttaatc ggatgttagt cgcaaatttt
    10801 cttaacccat cttctctatt tttacttaaa atcatccctt attcctcctt tgcagatggc
    10861 tttttaataa aggatactcc aaacataact gctagaataa gaacaagacc aatcacaata
    10921 cctgcttgtg agccaaattg atttaacatt cctaaaataa ttcctgatag accaaaatct
    10981 gcatctgaga aagttgatcc ttggaaacca agtcctccca aaactggcat taaaaagact
    11041 ggaagaaaac tgattaaaat accttgtaaa aatgctccaa tagtggcgcc acgaacacca
    11101 ccagatgcat tcccaatgac acctgcagtc gctccacaga agaaatgagg cacaacacct
    11161 ggtaagataa caaccgttcc tgaagcaatc ataattgcca tacttactaa accaccaaca
    11221 aaactagaga taaatccaat tagaactgca ttgggtgcat aagtataaac aatcggacaa
    11281 tccaaagcag gttttgaatt aggtacaaga cgctctgaaa tacctttaaa ggctggaaca
    11341 atttcgccca aaataaggcg aacacctgct aaaataacaa atacccctgc tgcaaattga
    11401 cctgctaatt gtaaagcata aactagacca cttgtaccac tactgatttc tttttctata
    11461 tattctgacc ctgcaaagat agctacaata atgtaaataa ctgccataga taaagtgata
    11521 ctaacagtac tatcacgtaa aaaagctaaa ctctttggaa atttaatgtc ctctgttgat
    11581 tttgatttgt caccgataag gctaccagta aaaccactca accaatatcc caaagaactg
    11641 aaatgaccta aagccacctt gtcatttcca gttaattgaa ccatatattt ttgcacaaat
    11701 gctggggaaa tactcataat aataccgagt gctaatcctc ctagtaagat gagaggcaag
    11761 ctagtaaagc cagcaactga taaaatgacc gcaatcatac atgccatata tagagtgtgg
    11821 tgccctgtta aaaaaatata tttaaatcga gtaaaacgag cgattaagat attgaacacc
    11881 atgcctgcaa acataatcat tgcagtagct gagccatatg ttgttaaagc tacagctaca
    11941 attgcttcat tattcggcac aacgccagat aaatgaaaag catgctcaaa catggtacca
    12001 aatggattta aagaattttg tacaattcct gcaccaccag atacaactaa gaaaccaaca
    12061 aaggtcttaa ttccaccttt aataatatca ggtaatttct tcttctgaag aactaatcct
    12121 aaaattgcaa ttaaagctac taaaatagct ggtgtactaa caatatccaa tatgaacttc
    12181 atcatgacgc tagcctccta tataagtcct ttttcttcac aaagtttagt aattaattct
    12241 cgtagttcat ccatatcaat aatactattt aagatacgaa catctccaag atgactagct
    12301 gaatcagcta gatcacgacc aacaatccaa atatcagctg catttggatc tgctccacct
    12361 aaatcataat gttcaacttc tacatccgaa acattcaaat cactcaatac agattcaata
    12421 ttcatctgta ccataaaact tgaacctaat cctgaaccac aagctgtacc aatttttaac
    12481 attatctaat cctcctgttt aattatcatt ttaatgtcat catagttttt tgatgatatt
    12541 aaagtttgaa catgattttt atctcttaaa attgttgtta aatgtgacaa agcctttaaa
    12601 tgactctcat tatcaatggc tgcaatacaa atcaacaatc ttacctcttg ttctggatta
    12661 tccaataaat aaatcggttc ttccaaaact aacattgaca ttcctatttc attcacacct
    12721 tcatctggcc gagcgtgagg aattgctact cccttcccta aattaataaa aggtccaaac
    12781 tcttctactt tttgaatcat tgcctcaggg tagttctcag ttatcttatc ttgatccaaa
    12841 agcggtttag ctgctaaacg aatcgcctcc ttccatccta atttttgcga actaacctga
    12901 taggtttctt tggtaataag ttgttctagc actggtacaa tttcctttct atcatttttt
    12961 tggtaaagat aattctttaa cgccaatctt aattccaatt cttgtgtaat aattccatat
    13021 cttttgacaa tattcaggat ttgttcaatc tcaaaatctc catactctaa attcggaaaa
    13081 tcttttaaca ctagttctac tagttgtatt gcttgctctt cagtcatcat aaccgaaact
    13141 agataatttg gcttttctgt ctccaccttt atggtagaaa aaaccatatc atagtcacta
    13201 ctagctttca cctgtaaatc atcaatcttt gaggttccta taaactcaat ttgaggaaat
    13261 aatgctaata gattctcttt taacatcaat gaagaactaa caccattagg acaaatgatt
    13321 gctgctttat agcatttttg aggcaaagta tctgctttct ttaaataacc tccgaaatgg
    13381 ataacaaaat atgctgtttc actatcaggt atgggattgt caatagcgtc catcaagggc
    13441 atcaaagaat ctttgactaa ttcaaataaa tcaggataat gttctttaac atgcaataca
    13501 tattcatttg aactaggtag gccgaacttt aatctatagt aagccggtat aaggtggcgg
    13561 cgaagatttt ctctcaatcc ttccctttgt ttaaaatgta acaaagaaat atcttccatt
    13621 ctacttataa tagcctctgt taattgatta aagtaaaccg gagcaacatc tacttcacct
    13681 tcaaagcaac ttgataataa aactgtgata tagcgataat catcctcaga aaacaccgta
    13741 tctataattc ccaaatcaac cactgtatcc aataaaatag tggttatatc ttgaataaca
    13801 ggagatacta atgtctctga aagacatact ctttcaacat ccctttgata cctacacaga
    13861 atgaatacta aaccgaaaag gcaaactttt aattgattaa caataggtac tagttgtagc
    13921 ttctcataat aatctttaac tacctgattt atcaaatcat aagttaatga atacccccaa
    13981 ctggataaaa cataatccaa accccaaatc cctatggagg attccagcaa ctcactaacc
    14041 atttgaaaag ctaagcggtg cttattccac tctgaaccgt gtaaagtata accttttgct
    14101 ctactgtacc ctagctccaa atcattatct aacataatct ttcttaatga ttgaatatca
    14161 gataaggttg tattcttact tactttcaaa aagtcttggt aatgattatt cgatataaaa
    14221 tctaatcggc aaaaagtgta aagatagatt aaagctaagc gagtcgactt tggtaaaacc
    14281 aattcatccg acttaataat atctgtcaaa gactgcttcg tacgatttga taaactatag
    14341 cgaccttgtt ttttatccag cactatccct ttattagcta gataaggcac taaataatct
    14401 attccttctt tgacttcctt tataggtaag ctcaccttaa cagataattc atataatgat
    14461 agctcacaat gatccatcaa agtcatcaaa ataactagtg ctctataatc aaacatttct
    14521 cttcctttct aactacaatt atagtgtaaa aattataaga ataaaagagt atttgagcac
    14581 aatataatct caccttttaa aagaaattat tgggctgaaa gtttttagtg attattttca
    14641 actttctatt gacttttaaa aacaaagtga tatcatttag atatcaaata atgggaggtc
    14701 attcttatga ctgaaaaact aatcaattca aaaccaaatg gtgtattcgc attgattctc
    14761 attgagttga caatcgtact tggtgtcttt atatttataa tgggtgttgg ttcggaaaac
    14821 atttttggaa ttattatcgg acctttacta atcgtaattg caggtctagc tcatgctggt
    14881 ttaaaagttg tcaaacctca ggaagctctg gttctgacac tctttggtaa ttatacaggt
    14941 accatcaaag aacctggttt ttactttgtc aatcccttca gcgtagcagt caaccctgca
    15001 aaccacactc gacttggaca aagtggtgat gttagcacaa aatctccttt tttaggagct
    15061 aaatcatcaa atgacaatga tgtaaatctt gaaattggca agaaacacat ttccctcaaa
    15121 gtcatgacct tgagcaattc tcgtcaaaaa atcaatgatt gcttaggaaa ccctgtagaa
    15181 atcggtatcg cggtaacttg gagagttgtc gataccgcta aggcagtctt caacgttgat
    15241 aactacaaag aatatctttc actgcaatgt gatagcgccc tccgtaatat tgtccgcatc
    15301 tatccttacg atgtgtctcc taatgtggat actacgggtg acgggcaagc agatgaaggt
    15361 agtctccgtg gctctagcga aattgttgct aaccgtattc gtgaagaaat ccaaagtcgt
    15421 gttgaggatg ctggcttgga aatccttgaa gcacgtatca cttacctagc ttatgctcca
    15481 gaaattgctg ccgttatgct tcaacgccaa caagcatctg ccattattga tgcacgtaag
    15541 atgattgtag atggtgctgt aggaatggtt gaaatggcac tagaacggct caatgaaggg
    15601 gaattggtag aacttgacga agaacgaaaa gctgccatgg tttcaaatct ccttgtcgtt
    15661 ctttgtggca atcatgatgc acaaccaatt gtcaacacag gaagtcttta ctaaagatgg
    15721 ctgaagctaa aaaaaagcag atcccccttc gactctcaac aaagttatac gctgcactcg
    15781 catcatgggc agaagacgac tttcgttcag tcaatggcca aatcgaatat ctcctcacag
    15841 agtgtgtcaa gcaacggaag aaagacggaa aatacgtatc agaaaccatt gacgaaccat
    15901 ttgagattga tatttaacac cttctcctgt ctgccgtgtc ggataggaga attttttcat
    15961 ctttttttgt caagtaactt tactttacaa aaaaaatgtg ttatcctagt atggttgatg
    16021 aaaatcagta gattgaatcg aatataaata cctaaaggag aaatcaaaat ggcagtacct
    16081 gcacgtcgca cttcaaaagc gaagaaaaac aaacgtcgta cacactacaa agtaacagct
    16141 ccatctgtaa actttgacga aactactgga gattactcac gttctcaccg tgtatcactt
    16201 aaaggatact acaaaggacg taaaatcgct aaagctgcat cagctgaata atagaaggga
    16261 gataccatgc gcgtaaatat tacacttgaa cacaaagaat ctggtgaacg cttgtacctt
    16321 acttctaaaa acaaacgtaa cactccagac cgccttcaat tgaagaaata ctcaccaaaa
    16381 cttcgcaaac acgttgtgtt tacagaagtg aagtaagcat tcaatacgaa tcaatacaga
    16441 agaaaaacgc ttgatcagcg ttttttcttt ttgttaattt cactatattg caagagaaat
    16501 cattcgaatg actacatttt ttgaaataag aatacggatt cggacgatta aaagtaagag
    16561 aaactcaaat gtaagttggg gttccttttt tgtatatttt tcaaataacg cctctacact
    16621 atttgtagca aattcaccaa ctacagttgc atcttagtta aaataagtta gaatatgtaa
    16681 gtgagtacca gatataccaa gacatcgtca ccatctaagg tatattcaaa atacaaaagt
    16741 tgaccaacta gatttctgaa tatccttata tatccattct taaaattggt ttaaatagcg
    16801 tagtctttta aactagtttt gagaatccaa aaaatcttcc tacatatgta agaagatttt
    16861 ttagttcaga atgattagat ttagctaatg gatacctatc ctacccactc accgttagca
    16921 ttgactcgat agccatcggg tgtagtcgtg tttactaata aatctcctga attataggta
    16981 tagtaccatt taccagaaac tgtaaaccaa ccagtagcca ttgaacctga ttc
//
LOCUS       DAVHKZ010000042        15371 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000042 DAVHKZ010000000
VERSION     DAVHKZ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15371
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.042"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(62..859)
                     /gene="proC"
                     /locus_tag="VVO74_001778"
     CDS             complement(62..859)
                     /gene="proC"
                     /locus_tag="VVO74_001778"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU5695766.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFYQLLAKAGLLVELGES
                     LIDAATGLAGCGPAFVYLFIEALADAGVQTGLPREIALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(863..2125)
                     /locus_tag="VVO74_001779"
     CDS             complement(863..2125)
                     /locus_tag="VVO74_001779"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU5695767.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAIGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(2135..3265)
                     /locus_tag="VVO74_001780"
     CDS             complement(2135..3265)
                     /locus_tag="VVO74_001780"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU5695768.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VVO74_001781"
                     /gene_synonym="pce"
     CDS             complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VVO74_001781"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU5695769.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(5231..6118)
                     /locus_tag="VVO74_001782"
     CDS             complement(5231..6118)
                     /locus_tag="VVO74_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU5695770.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(6108..6569)
                     /locus_tag="VVO74_001783"
     CDS             complement(6108..6569)
                     /locus_tag="VVO74_001783"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU5695771.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(6566..7474)
                     /locus_tag="VVO74_001784"
     CDS             complement(6566..7474)
                     /locus_tag="VVO74_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU5695772.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            7467..7664
                     /locus_tag="VVO74_001785"
                     /pseudo
     CDS             7467..7664
                     /locus_tag="VVO74_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(7716..8387)
                     /locus_tag="VVO74_001786"
     CDS             complement(7716..8387)
                     /locus_tag="VVO74_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5695773.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVIMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(8441..8662)
                     /locus_tag="VVO74_001787"
     CDS             complement(8441..8662)
                     /locus_tag="VVO74_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEU5695774.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            8934..9743
                     /locus_tag="VVO74_001788"
     CDS             8934..9743
                     /locus_tag="VVO74_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU5695775.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VVO74_001789"
     CDS             complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VVO74_001789"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU5695776.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVLAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VVO74_001790"
     CDS             complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VVO74_001790"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU5695777.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VVO74_001791"
     CDS             complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VVO74_001791"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU5695778.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(13018..14277)
                     /locus_tag="VVO74_001792"
     CDS             complement(13018..14277)
                     /locus_tag="VVO74_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU5695779.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VVO74_001793"
     CDS             complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VVO74_001793"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU5695780.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            complement(15165..15302)
                     /locus_tag="VVO74_001794"
     CDS             complement(15165..15302)
                     /locus_tag="VVO74_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695781.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
BASE COUNT         4490 a         3569 c         2820 g         4492 t
ORIGIN      
        1 agtttgaatt tgattttcga agagtatcaa ccaccataaa agaggcagat aaaactacct
       61 cttatttacc tagttcttgt gttcgtttgt aggcttgatg aactgcatcc atgactgttc
      121 ctcggaaagc atgcgcttct aggcttgcta caccagcgat agtcgaaccg cctgggctac
      181 agacttggtc tttcaatact ccaggatgtt gctgactttc aaggaccaat tgcccagctc
      241 ctaccacagt ttgtgctgcc attttcaatg ctatttctcg tggtaatcct gtctgaacac
      301 ctgcatctgc caaggcctcg ataaaaagat agacaaaggc tggtccacaa cctgcaagac
      361 ctgtcgctgc atcgattaaa ctttctccta gttcaaccaa gagaccagcc ttggctaaaa
      421 gctgataaaa gagctcactg tcctcagccc tgcaattagg agacaaggca taactaatca
      481 ctccttgccc gatagaagca ggggtattag gcatcatacg aataattcgg tgttgacttg
      541 ggataagact tgctagtttt tctaaggtca atccagctgc catcgaaatc aaaagaagac
      601 tttctctttt ttcaaggatg gtctggtatt gagaaagcag ttcagaaaac tgagcaggct
      661 taactcctag aaaaatcaca tctgcttctg caaacatttc ttcattgctg gaagcctgac
      721 caccaaagtc tgcaatgaaa gcatctacct tagcttgact acgattggca aggagaatct
      781 catctgacgt cctagtctgc aagacagatt ttgccaagct agcacccata ttccccaaac
      841 cgataaatcc aatcttcatc tcttactccc ttatctgccc atcaccggca accacatact
      901 tgtagctggt caactctttc aagcccatgg gaccacgcgc gtgcaatttc tgagtagaaa
      961 tccccatttc acaaccaaga ccaaattgtc ctccatctgt gaaacgagtt gaggcattaa
     1021 catacaccgc tgcagagtcc acttgatctg taaagtatgc tgcagcttca gcattttccg
     1081 tcacaatagc atccgaatga tgggtgctgt gggattcaat gtgcgcaacc gcttcttcta
     1141 aactgctcac aaccttaaca gcaaggacat agtctaaaaa ctcggtgtca aagtcttggg
     1201 tctcagctgc ttgacctgaa acaaactggc ttgctttgct atccaagcgg aattgaattg
     1261 gttccagtcc agcttcctta cgctctgcaa ccagcatttg atccaagcga ggaaggatgc
     1321 ttgctgcctt gttttcatga accagcagaa cctccatggc attacaaaca gaaggacgac
     1381 tggttttagc attgttgatg atagacagcg ccttgtcttc gtctgcatcc ttatccacat
     1441 agacatggac aatcccagtc cctgtctcga taacaggtac aatcgcattc tcaaccactg
     1501 cattgatcaa gccagctcct ccacgaggaa tgagaaggtc tagatagccc ttggccttca
     1561 tcatagcata actactttca cggctagtat cctccaccag ttgaatcaca tttggatgaa
     1621 tagtagtcgt ctccaagccc ttcttcaagg ctgtgacaat ggcatgggtt gtttgatagg
     1681 catccttacc actacgaaga acaaccgcat ttccactctt aagagtcaaa gcagccgcat
     1741 cagacgtcac atttggacgg ctttcataga taataccgat gacacctata gctacacgtt
     1801 tttttgtgat aaccaaacca ttttcaagct gacttgtttc taaaacttca ccgattggat
     1861 ctggtaaggc aaccacttca cgaattcctc ttgccatcgc ttctatacga tctgcatcca
     1921 aataaagacg atccaacatc acatctgaga ttttcccctt agccgctgcc atatcgaggg
     1981 cattagccgc taaaatttcc tcagtagcag ccactaagtg atcagccatg gctagcaagg
     2041 cttggttttt cacttcttca ctagctgtgt taatcgattt tttaacagcc tgtacctgtt
     2101 caaattgttc ttgtctactc accatagttt acctctaaaa ttctgtaaaa agtagttgga
     2161 tttcaggagt aatggaaatc cagtcgtcac ggtaaatcaa gacacccttg gctttttgag
     2221 aacgcaacat atcctccaaa gcagatgctc caaattgcac gcgtcctttt ccaagtgatt
     2281 ttccactttc cttgtcaaat actgtcacga tatcaccgta agaaaaggct ccttctgctt
     2341 caacgatacc agataagaga agactctttc catgttgaga gagagcttcc gcagcccctt
     2401 tatcaaccca aatagaacct tgactctgag catagaaggc aagccattgt ttctgggtac
     2461 gaagcccctt ctcttgagca acaaagtaag aaccatcctc ggtctcctct gccgcctcaa
     2521 tcatggaatc tgatttcaag gatgagcaga tataaacagg aactcctgat tccgtcgcga
     2581 tagttgcagc cttgattttg gttaacatac ccccagttcc gtttgacgaa ccagctccac
     2641 cagccatatc aataatctca cgattgatgg tctcgattct ctccaagcgt ttggctcttg
     2701 gatctgaatt aggatttcca gtatagagac cgtccacatc tgtcaagaaa actaaaaggt
     2761 ctgcttggac catcgccgct acttgagcac ttagagtgtc attgtcccca accttgagct
     2821 catcaataac gacactatca ttctcattga tgataggaat tgccccacgg ttgagcaaaa
     2881 ccgacaaagc ctgatgggca tttttataac gacgcttatc cacaaagtca tcttgggtca
     2941 gcaagatttg tgcagaaacg atttgacgca agagaagatt ggtcgtatat tcttccaaca
     3001 aaagtccctg ccctaccgct gctgaagcct gtttatcagc aattttagtc ggacgctttt
     3061 taaatcctaa ggctccaaaa ccagccgcaa tggcacctga agacaccaaa atcaactcat
     3121 gaccagcctc gtgcagcata gccaactgct gggtaatatc ctttacctta ctacgtgata
     3181 aacttccatc ctcatttgtc agagaagaag tacccacctt aaagacaatc cgtttgtatt
     3241 tcatagtctc actccgatta ttcatattta tccattataa catgaataac aggaaataga
     3301 aaagagttga taggaaaaag aaggccctaa aaccttcttt tctactactg ttctgattcc
     3361 gatttgttta cactcgtttc agagctttgt gaagttgagg atgtcaaatc ttgactagtt
     3421 gaaaaatttg taacactttc atgttgactc gtttctttat tttcaagatc ctttttcact
     3481 acttctttgg attcttttat ttctgaatga cttgtagttt taattgtagc agatttctcg
     3541 atcgaaacat ccactaacca ggcaccactt gaatccacag tataaccttc tggtgtctta
     3601 ccgttcacaa gtaattgacc attttctttc aagaagtacc atttatcctt gtccttgatc
     3661 caacccacag ctcgtgaacc gtctgtcttg tagaaatacc aatcatttgc ctttttatgc
     3721 cagccttgct tcatagctcc tgaatcttcc agataataat gttgaccagc aacttctatc
     3781 tcacctgtct tcatgacacc agtagaatcc atatagtacc aggtttcttt atcttttacc
     3841 cagcccattt tcatttcccc tgatggagca aagtaatacc attgccccat atattgaagc
     3901 catcctgtct tcatagaacc atcaacatcc aaataatacc actgctcttt atcttgaatc
     3961 caaccaattt ccatctggtt ttctttgtta aaataatacc agattccagc gattttcttc
     4021 caatttttag cagaagcacc agagtctgtc aaatagaacc aatgattgtt ccattttttc
     4081 cattgattct gtaacaagat acccgtttgg ttaaagtaat accattcacc ttcgatttca
     4141 ttccaaccga cagcatactc tcctgtagaa tcaggcgctt gataccacca gttcccatat
     4201 gcactcttat gccaaccagc ttgaaaactt ggaatcggct tgtaggatgt tgaaatattg
     4261 acaaaaccgt cttttcgaat atcaaaaact gttgcatcat agtctttgct ggctgcgttg
     4321 attctctcaa ttcctcgttc tttgagccaa ttaacatact cactatcaac accatttttc
     4381 caaggtagac tatccgaagt ttgaacaatc aaactcggac tcaaattttt aatgaaatcc
     4441 ttggtatttg atttgttggt atcatggtga tgattaaact tcatcaaatc aacttttcca
     4501 atgagaggac catacttgtc ttctgctcca tgaacattat ctaaatcgcc cccaaggtaa
     4561 attttcttgc cattgacttt caccacgcta atcaaggaat tggaattgtc atcccaaatt
     4621 ttctttaatt cacccgatga atcagtttca ttttcataat tatagagctg aatatccatg
     4681 tccccaaact gaaaatgagc atccccttgt gtgatatttt gaataactga aacacctttt
     4741 tctgcagcag tctgtaaaac cttatcatag ccatacagat tatcccatag acgttcagaa
     4801 ttagtaatac gactatcact atatttctta agatagactc ggtcaactgg ataggtagac
     4861 agtaattcat caacatttcc aatatgatca ctgtgggtat gggtcaccaa aataaaatca
     4921 agtttttgga cacccaattc cttcaaacga cgaaagacac ggtctgttag aacatgctta
     4981 taagacgttt caattccttc tctccatgga tagcgagaat cacttccatc tgggaaatca
     5041 taatcttctc ctgtatccac catggcaaaa tgtccattgc tttcaagaat aatcgcatca
     5101 ctgccacctt cttgaacatt gataaagtgg attttatttc ctgaactttc ttgagcctga
     5161 acattcccat accatgacaa acctaaaaaa gcgcctacaa gtgctaaact agttaatttc
     5221 tttttcattc ttactttctc aatctctcca aggtttcctt aaaaatctct gggatatctg
     5281 ctttaaattc caaggtctta cctgttctcg gatgagtaaa acctaaagtc ttggcatgaa
     5341 gaaattgtcc atgtcctttc aaagtcttgc gaggaccata gacctcatca ccagcgactg
     5401 gatggccgat ataagccatg tggacacgga tttgatgagt gcgccctgtc tccagttgca
     5461 actctactaa gctataatcg ccaaagcgtt ccaagacgtg aaaacgcgtc actgcaggct
     5521 tccctttagc agttacagcc tgtttcttac ggtctttttc actccggcca atcggcgctt
     5581 caattacacc acgatcatta ggtagatttc catgaacaat cgcccaatat ttgcggagag
     5641 actttttatc cttgagttct tgggcaagtg ctagatgcgc atcatcgttt ttagcaatca
     5701 tgagaagacc tgacgtatcc ttatcaatac ggtgaacaat ccctggacgc agaaccccat
     5761 tgatacccga caagtcctta atatgataca tgagggcatt tactagggtt ccactggtat
     5821 gaccagcact cgggtgcaca accattccct gaggtttgtt aacgacagcc acatcctcat
     5881 cttggtagac tatttctagc ggaagatcct cagccacata ctctaatacc tctggttctg
     5941 gcacatggta agtgacgaca tcaccctctt ggactgtgta tttagctttc ttgacttgac
     6001 cattgaccaa gacctggcct gatttaattt gttcattcgc gagactacgt gataattctg
     6061 acaaatctga caaagcctta tccaaacgca gaccaccagt ttcaatttta atttccattt
     6121 atttcctctt ttagcattgc aatcaataaa ataatcactc caaccgtcag atagctatct
     6181 gccacattga aaattgcaaa gttgataaag tcaaggtgga acatatccac aacaaagccc
     6241 tgactgaccc tgtcaataaa gtttccaaga ccacccgcga ttattagagt caaacccaag
     6301 accatccaga atgagtcctc catgtgttta tgtaaatacc aaatggcacc tatcacgaca
     6361 accagagtaa tgacagcgaa taacaactgc tgatcttgta agatagaaaa ggctgcacct
     6421 cgattttgca ggtaggtcaa gctaacgaaa ttggggatcc aggagcgcac ttcacccagt
     6481 ggaatctgct ggacgatata ggatttgacc aactgatcca gcccaatcaa aagcagtaca
     6541 atgactgcca ctattgctct ttttttcatg atttcctctt ttgatcaaaa tattcttgca
     6601 tgacttctac gaagagagtc ccagcttgac taagctccac ttcttcacgt ttaacataga
     6661 ccatgcggtt atctaggtta tccttgagac gaataactgt aatgccatta acactgtcac
     6721 tatctaaaaa tccagaacct gtcgcatagg cgtccgtccg ctccaaaata ccattcaagg
     6781 tggcacggtc tgtcacatta aacatctgtg agctagcgct ggtatcaaca aagttctctg
     6841 aataataaag gtactcgtct ttctcttgag tgaaacgaac cgttggtaaa tccgctaaat
     6901 cctccatgac taattcctct ttctgggcta aaggatgacc ctcacagaga taaatatggg
     6961 tatggaaagg aatcaattcg atgacctcca gacctaactt ttcaacccgt tgcataatcc
     7021 cctttttatt ttgattgttg aggtagataa tcccaatctc actatgccct tgcgccactt
     7081 catctaatat ttgaacagta gttgattcaa aaatacggaa gttcttatag tcaggatagc
     7141 gctctgaaaa ggccgtaata gttggtggta agaagtcata gtgctggcta gcaacggaaa
     7201 attcatcttt ttcttcttca ggattggcat actgattttg aaaaatatca aatcctttaa
     7261 ccaattcttg cgctttttca taaaattcca tcccacgacg ggtcaagaaa gtccctgagc
     7321 tggtccgacg gaaaatctta aaacccaact ctttttccaa atcccgaaca gaaatagaca
     7381 gactcggctg actaacatac atcttttcag cagcttcacg aaaagtacca ctattggcaa
     7441 tagccacaac atagcgtaat tgttgaatgt tcatcttcta cccctaactt ctttatcttt
     7501 tcattatacc atattttaga agttttccaa aaaggaaaaa agaacatcct attcttctta
     7561 actatcttca ctatctgcct ttctcaagcc aaccttattt tcaaaatcaa ttcaaaaaaa
     7621 taactggcta cacaccacta caatatcgaa aagaaaaacg ttgactattt gtgaaaaaag
     7681 aaaatgccgg aaagttccga cattatttta gtaagctaac ttcctgaaaa taggagcaac
     7741 cacacatccc agaaggcagt gatattaatg agaatatgaa ctagtattgg atagtagaga
     7801 tttttagtca tgcgatacaa tagagctaaa ataagacctc cactagcata aatgaaaaaa
     7861 gcaagaggag ttaaagcaaa attgatatga atataaccga aaataatagc agaaagcaaa
     7921 acatctccgt accaaggcga gtttttgaaa aaggttgtca taatcacacc gcgataaatc
     7981 aattcctcag caataggggc gatgaagcaa acgatgagca agaaataagg gaactcctgt
     8041 ctccccatca tttctaccgt ttcattcaaa gaaatctgat ttgaagacag ggatatgaaa
     8101 tacgaaaaga ggaagtcaga catatatgaa atgatgtagc ccagtaaaag gtagatgaag
     8161 tacctcagct gccacttgaa atgaaaaatt ttctttcctg caaaaaccag tagatagatg
     8221 accgctaaga aaagaactcc gctctccatc aaaagcagaa tctgaaaaaa ttcacgactt
     8281 gctggtagat agggctttgc gaggtgattg aaaactctcc aaaaccaagt tgatttgtaa
     8341 aaaattaagg acaatgctag taaaatttga atagcccgtt ttttcatatt aaattctctg
     8401 ctttctccac ttgtttcttc atattactaa taaattttac ttaaaatctc gcagcacttc
     8461 ctttgcaaag atgattgcct cctccaatat atcctaaatc ataggtgcct ctgggacaaa
     8521 atccatgaac cggcagagtt aatactggtt ctatttccca atcgtaccta ccattaggat
     8581 ttttaccata tgaatctgct ccaccttgta tcagctctaa ttcttcattt gttagattta
     8641 tattttttgt cattaaaatc atgatatatt tcctccatta ttcttcagat tagttgagta
     8701 atctgatact catacctact tacaaaaaaa ctattatatt aagttggttt tttaatttgt
     8761 ctagttgcaa cattgacaaa catagtatag catatctttg cgaaatatcc tcttcaaatc
     8821 atgaattgtc atcaaaacat cttaaactat aaaatcaatt agtctcaagc tttctatcaa
     8881 tttcttctcc aaaatatgct ataataatag caaaagataa agaaggaaga cctatgatta
     8941 aactactagc cttggatatg gatggaaccc tcctcaatga agccaaggaa atcccacagg
     9001 ctcacatcgc tgctattcac caagccattg aaaaaggtgt caaactggtc ctctgtacgg
     9061 gtcgccccct tttcggtgtc ctcccctact acaaaaaact gggactcgac ctccagaacg
     9121 aatatgtgat tgttaacaac ggttgttcaa ctcaccagac tagcgactgg ggcttggttg
     9181 actggcaaga actgagtcca gctgacatcg aatacctcta tgaccttgct gaaaagagtg
     9241 atgttcagtt gacacttttt gacgagtcac attattttgt tctcggtggc aagcccaatc
     9301 aagttattga aaatgatgct aaactagtat tttcagacct gactgaaatt tctcttgagg
     9361 aagcgactag tggaaagttc cggatgttcc aaggtatgtt tttaggaaca aaagaacaaa
     9421 cagacgattt tgagcagcgt tttgctgaag agctttgcca acgattcagt ggagttcgtt
     9481 cgcagcctgt catttatgaa gcaatgccac ttggaacgac aaaggctact gctctttcac
     9541 gactagctga gattttgaag attgattcct cagagattat ggccatgggc gatgctaata
     9601 acgatatcga aatgctccag tttgcagggc ttgggattgc aatgggaaat gccagcgatt
     9661 atgtcaaatc tcttgcggat gccgttacct caagcaacga agaagacggc gttgcgcgtg
     9721 ctattgagaa atatattcta taaaaaagaa aagcaaatag acagaagtta ctgctatttg
     9781 cttttttgct aatattttaa aatacggact aatcaataga caagaatagc gaatcataaa
     9841 aatcgattta ctagatgcca tagtatctta tagttgctaa taagaagtta gtctagcaga
     9901 atgaatctct catttctccc acactaatct gtaatttgtc tatacatttc tggtcttcta
     9961 tctcgaaaca agccccagtt taggcgttca ctcgctccct tgtctaggtc ataagtagct
    10021 aacagaacag cttcttcttg tctttcagct cgttctagaa tagctcctgt ttcatccgtc
    10081 ataaaggagg aaccgtagaa gtcaagactg gaactctgtc cgccattttc ctcactagga
    10141 gtaacctcct ctaaaccata acgattggct gcgatgactg gaacaatatt cgctgctgcg
    10201 tgcccttgca tagtacgttg ccagtgacca caactatctg tatccaaaat cggctctgaa
    10261 ccgatggctg ttggataaaa gagcaattca gcaccattca atgcaagaca gcgcgctgtt
    10321 tcagggaacc attgatccca acagataccg ataccaatct tagcatagcg agtattccag
    10381 accttgaaac cagtgttacc aggcgtgaaa tagaattttt cttgataata atggtcatct
    10441 ggtatgtggg tctttcgata aacgcccagc acttccccat ctgcatcaat gacggcaata
    10501 gagttataca agacattacc atctttttca tagaaactga ttggtaaaac aacttgtagt
    10561 tccttagcaa gcaccttaaa atgctgaatg gcagtatttt ccgctacaga ttgggcatac
    10621 tggtagtagt catactgacg ttcctgacag aaatagggat gttcaaacaa ctcgggcaag
    10681 agaataattt gggctccttg ctcagcagcc tgacgtacta aacgctctgc ggtttggata
    10741 tttgttgcca catccttagc gcattgcatc tgaatggttg caactcttac atttctcatc
    10801 tttttctcct attctggaat ttgttgggtg atacagtgga tattgccacc acctaagaga
    10861 atatctctgg ctggtattcc gacaacttta cggtctggga aacacttgct gaggatatct
    10921 aaggccactt ggtcgtttac atcctcaaac tgtggaacca agacagcctt gttggcgata
    10981 taaaagttta cgtaggaagc tgctagtcgt tcacctgcgt atcgcttttc ttctccttct
    11041 tcatagatgt agcctggcaa atcttcttct gtcacaactt gtcgaactgc agggataggc
    11101 aatttatgaa tggtgaagtg acaacctttt gcatctgttt cctgttctaa gagttcgaga
    11161 tctgcttttg acatggcata ctggggatca ttttcgtcat ctgtccaagc caaaacaagc
    11221 tcagcaggac caacaaaggc agcaacatta tcgacgtgtt cattggtttc atcctgataa
    11281 ataccataag gaagccaaat aactttttca gcaccaagac tttctaataa tgtgttttca
    11341 atctcctctt tagtcaggtt aggattgcga ccaggactaa gcaagcaact ttcagttacg
    11401 agaatagttc cttgaccatc gctatggatt gcgcctcctt ccagtacaaa aggtttagca
    11461 tcatagacag gcctttccaa ggcctcagca aaacgactgg ctacttggtc atcctcttca
    11521 taatcttgat aaagaccatc ataggtgcct ccccaagcat taaaggccca atccacggct
    11581 aatttcttac ctttatcatt gacgagaatg gttgggccag tatcacgcgc ccaggcatca
    11641 ttggtgggaa tgtctaaata aacaaccttg tctccaagat aggattgggc ttcagataga
    11701 taggcctgct ccaccaaaag atagactctt tccccttctg ctatggtctc gatgatctga
    11761 gtaaatgctc ttttagcagc ctttccttga aaaggccatg atcctggtcg agtcggccat
    11821 atcatgaggg taccatgatg gggttcgtac tctgctggca tgtgatagcc taattttttt
    11881 ggactgtcca tcatgataat ctccctttaa agtcttgata gccaaaagct ttgagtaagc
    11941 tacagtctcc ctgttcgtcc atgagataga gacttggcaa tccaatacca ttaaaggtat
    12001 tatttttgac aaaagaataa atggccatgt cttgaaaata aagtctgtct ccgatttgga
    12061 ctggattttc aaaactataa tcaccaatca catcgcccgt cagacaggta ttagaagaaa
    12121 gtctgtaggt atgggctttt tcctgtgact caaagccatt tctcaaaggt ggacgatagg
    12181 gcatctcaag tacatcaggc atatggcagg tcgcagaggc gtctaaaacc aagatttcca
    12241 taccgttttc tacaatatct aatacctcag ttgctaaata acccgcatta agcgcaatgg
    12301 cttcaccagg ctcgatatag atttcaagat tgtaagtttt tcggatacgc ttgatttctg
    12361 aaatcagcaa atccacatcg taaccttctc ttgtaatatg atgaccacca cccatattga
    12421 gccattttac ctcatgtaag tagggaccaa actgttcttc tactgctttc aaagttgttt
    12481 gtaaatcatc tgctccctgc tcgcaaaggg tatgaaaatg aagtccgtca accaaatcta
    12541 gcaaatcact cggaatcttg tctatagtaa ctccaaagcg agaacctggt gcacaagggt
    12601 catagagcgc gtgatctcct tgagttgaac actgagggtt gaggcgcaaa ccaacactga
    12661 caccagcctc tcgacaacgc ggaccgtgtt tacgcaactg tctctctgag ttaaagacga
    12721 tatggtccat tatctctagc aattcctcca agtctgcatc cttgaaagca ggcgcaaata
    12781 catggacttc accaggaaat tcttcccttg ccaatttggc ctcatagagt ccactagctg
    12841 tcgtacctga tagatactgg ctaatcaagg gataagtttt gtagagggaa tatgccttct
    12901 gggcaagcaa gaccttgcaa ccggcctctt cttgtacata ttgtagaatg cggcaattag
    12961 cttctaactt ggccaagtca ataacatagg ctggtgttgg tacttgttct aacttcatta
    13021 gtccaccatt tgtggatttt caaccacaac ccatggcaaa ccatactcat tcaaagcttc
    13081 catgaatgga tctggatcta actcctcaag gttatacact ccagcttgtt tccaagttcc
    13141 gttcatgact aattttgtcc caatcatggc tggaactcct gtcgtataag aaatagcttg
    13201 cgaaccaacc tctgcgtaac attcctgatg gtcgcagaca ttgtagatat agatagtctt
    13261 tttgacaccg tctttgacac ctgtaaagat acatccaata ttggtttttc cgactgtacg
    13321 tggcccaaga ctggcaggat ctggaagcaa ggctttcaaa aattgaattg gaacaatttc
    13381 ttggccgtta aagttaatgg tatccgtacg aaggagtcca acattttcaa gacatttcat
    13441 gtgcgtcaag taagattgac caaaagtcat aaagaaacga atgcgtttga cacctggaat
    13501 gttcttggcc aatgattcga tttcttcatg gtgaaggaga tacatatctt tttgtccaac
    13561 ttgagggaaa tcatactcac gcttgataga catagcttcg acttcgaccc atttcccatc
    13621 ttcccagtaa gaacctggcg cagaaacctc acggagatta atttctggat taaagttggt
    13681 tgcaaatgga taaccgtggt caccgccatt acagtctaaa atgtcgatat aatggatttc
    13741 atcaaaatag tgtttgaggg cataagctga aaagacacta gttacacctg ggtcaaaacc
    13801 agaaccaaga agagcagtca agcctgcttc tttgaatttc tcttgataag cccactgcca
    13861 tgagtagtca aagtaggctg taaaaccaag ttccttacaa cgtttttcgt agatagcacg
    13921 ccactcaggg tcttctgtgt cttctgcttc gtagttggct gtatcgatat agtgaacacc
    13981 tgttgccaaa caagcatcca taatggttaa atcttgataa ggcagagcta cattcaaaac
    14041 agcttctggt ttgtagcttt caatcagggc aatcacttct tcaaccttgt cagcatcaag
    14101 tgctgcagtt tcaattttag tacttgtttt gccttctagc ttcgctttca agtcatcgca
    14161 ttttgacttg gtacggctag caatcataat ctctgtaaat gtttcgctat cttgacaaat
    14221 ctttgaaata gcaacttggg caacgccccc acaaccaata actagtaaac gactcatttt
    14281 tttccttcct cttcttctaa aatgtcctca acatacttgg gcaacataaa ggctcccacg
    14341 tgtaagtttg cagtgtagta ttctgtgaaa agctggcgtt ttttccagcc ttccttgtca
    14401 aaatctttga cagggtggta ttttttcgat gcaaatccaa acaaccaata gccagctggg
    14461 ctagttggaa tatgggcctg ataaacccga ctgattggaa aggcttgatt gaccttgcgg
    14521 tgcatgcttc ggcaggccga ctcatcctcg tcaaagaagg gactcccatg ctggtaaatc
    14581 atgatgccgt cttccttcag agctcgataa ctattgccgt agaattcctt ggtaaagagt
    14641 ccttccgtat ggccaaatgg atctgtcgca tcgttgatga taatatcgta atcatcttcg
    14701 cagtttcgca aaaagcgtag cccattttgg tagtaaatgg taacacgagg atcatctagc
    14761 cctgcagcaa agtctgggaa atactcacga cagacctcga ccaacatctc atccggttcc
    14821 acaatatcaa tttgctccag ttcaggatag agggttaata cttgggcaac accgccgtca
    14881 ccacccccaa taaccaatac tttctttgga tttgggtgga cagccatggg aacgtgaacg
    14941 gtcatttcat tgtagacgaa atcatccgca tctgagaaca agacatggcc atttaaaatc
    15001 agtattttcc caaaagctgg cgtatccaag acttcgatat cctgccattc actttttcca
    15061 gcgtaaagtt gcttggctgt tctcagagac aatttgacat ctggagtatg aacttcagaa
    15121 aaccataaat ccatctattt ctccttatat tatatttagc gcagttagct actgccaaag
    15181 cccaagtggt atacttggaa taagccactg tggattagtt catttcctcc aatcgcttga
    15241 cgatttccga aaggctctaa ccacagcttt tgtttcaatt ggtaatgagt ttgataacgc
    15301 atagacgttt tatctcgtct aaggtaacaa ggcaaaaagt tcgtggataa ccaagtagac
    15361 ttgaaatact a
//
LOCUS       DAVHKZ010000043        15074 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000043 DAVHKZ010000000
VERSION     DAVHKZ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.043"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            193..402
                     /locus_tag="VVO74_001795"
     CDS             193..402
                     /locus_tag="VVO74_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695782.1"
                     /translation="MEWTDWVDLEPETKTDIKTKIENDGYTFPHYDKKNNGVKYVIST
                     MDIKRDCLRIGVPFEDVYPLQTTLF"
     gene            417..752
                     /locus_tag="VVO74_001796"
     CDS             417..752
                     /locus_tag="VVO74_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001189839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695783.1"
                     /translation="MQRTAVINTPFTIVTSKTEQNIEIVGSSLWSPVAEFVKQDRQLS
                     LDENGDLFEPEYKLVLEAKQSVDMILDSAYAAGEFAKDTKEVQTLFKFIEENKKNLFE
                     ELGFHGVLL"
     gene            749..1180
                     /locus_tag="VVO74_001797"
     CDS             749..1180
                     /locus_tag="VVO74_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HEU5695784.1"
                     /translation="MKLVLNIEPKPQSRPRFARRGSFTTTYEDKDMKAWRNHCQLLIA
                     NQYMGQPLLEGALRAKVRFYIKPPQYISKAKKNQQALLDEIIPVGKKPDIDNYEKALY
                     DSMSGIVFQDDGQIALHDVGKFYSLNPRIEVEVEVMEPLSI"
     gene            1285..1773
                     /locus_tag="VVO74_001798"
     CDS             1285..1773
                     /locus_tag="VVO74_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEU5695785.1"
                     /translation="MNKQELIGRIKRLDESYLKTEFVLKLIEQLDEPKPVKVPQFVAE
                     YIEYAKNNYWDLQDLFKFIDDEENKNLQRWFYHECEQETLALAWLFGYEVEGEKRYFV
                     KMKGIAKYKNYLVFGEISRTWFFASVGSNDVTFTHTSKELEEAGFGWVFNCEGIEVEE
                     VE"
     gene            1773..2366
                     /locus_tag="VVO74_001799"
     CDS             1773..2366
                     /locus_tag="VVO74_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695786.1"
                     /translation="MEDTIWLEWIAEVMATKPVGNELLESQRGQEVVDLLLDLESNDF
                     NWHRGDADTFWIDAQMCIKYQLSNAEIKFLAKQQPGVVNYKKHAKERNAYSEMMRGLE
                     KLKELNFPEIYNHSLSPEEEKKKFEEEMAIEQKYISPYQKLDELEKRFFENQFLFGQK
                     VMEAAMKIVSSEKKITVDNFFNIGSHRIKFTVEEVTN"
     gene            2363..2611
                     /locus_tag="VVO74_001800"
     CDS             2363..2611
                     /locus_tag="VVO74_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HEU5695787.1"
                     /translation="MKNTLIRFLLAWSLIATCLLFMQREAQKPLLVYYTDSKYQITGK
                     VEEKRKIGNLFTITVNGNVFVVNEQKYKNIEIGDNIEL"
     gene            2673..2960
                     /locus_tag="VVO74_001801"
     CDS             2673..2960
                     /locus_tag="VVO74_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695788.1"
                     /translation="MAKDILTDLAFENFHKCMGITDWKESDEVILVSLANKEQIESDE
                     SYRSAGKCNYLGKRICIFCTQVKKNNYITLHKSFLEKVIKTMESFKDVEEK"
     gene            2962..3360
                     /locus_tag="VVO74_001802"
     CDS             2962..3360
                     /locus_tag="VVO74_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695789.1"
                     /translation="MKIKKIVAVISVLSALLLLTACRESEKVSYNVSQEADNFNIVRR
                     VAVINTRTDKVEFEVIGRISVETEANEGKRLEILVETAKGVYKKHMVNLTSWNMYVVE
                     DLEGAEVDQYKYEVNYMPESIIPFKVTKKD"
     gene            3437..3898
                     /locus_tag="VVO74_001803"
     CDS             3437..3898
                     /locus_tag="VVO74_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEU5695790.1"
                     /translation="MNKAKELLKELQDLDIDIQSRIDEINELEAGLLSSPKWTDVKVQ
                     GGQARKVDDVYTQLVVMKEAIEQDTKEVIDRKLELGRMINRLKNPKHRTILRKTYINK
                     MYVDDICESMGGMSSPTYYRLKKQAVNELDVILSELIVNDSNGTGMKSKIC"
     gene            4083..4155
                     /locus_tag="VVO74_001804"
     tRNA            4083..4155
                     /locus_tag="VVO74_001804"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4116..4118,aa:Glu,seq:ttc)
     gene            4218..4550
                     /locus_tag="VVO74_001805"
     CDS             4218..4550
                     /locus_tag="VVO74_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695791.1"
                     /translation="MILAKKTKRGRPTKMTQGTLRKLEELFVRGLSDEEACLLADIGT
                     TTLYDYCKENPEFSERKELLKQRVKIRAKLNISKAIEDGDTDLSKWYLSVEIMILRQN
                     KQSHTAEK"
     gene            4614..6002
                     /gene="terL"
                     /locus_tag="VVO74_001806"
     CDS             4614..6002
                     /gene="terL"
                     /locus_tag="VVO74_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HEU5695792.1"
                     /translation="MDKAALKRQAQLELARRNFFYYCQLMAGDFYKSERIYLKQLCDS
                     FQNFMSDDEHNVLIINIGPRHSKSRTAGMFVQWLLGNDNTKKIMTGSYNDTLSTVFSK
                     SVRNAIQEEKADDSITVFSDIFPDTKIKRGDGAMNLWSLEKGYNNYLATSPGGTATGF
                     GADVIIIDDLIKSALEANNANILEGHWEWFTNTMLSRFEEGGKLIIIMTRWHSEDLAG
                     KALSKLPESGYSVKHISMRTYDEETDTMLCEDVLSKESYFRKVKAMGADIASANYQQE
                     PIDIKGRLYSEFKTYVDRPIFKRISAYTDTADTGKDYLASYIYGETMDKEAYILDILF
                     TKEPMEVTEPLLARKLVENEVNLCWIESNNGGRGFARNVERLMRENHGTNQTTVKWFH
                     QSKNKQARILTNATWLMEHVYFPEGWRNRWPELYKSLMTYQREGRNAHDDAQDALTGI
                     AEKITANSSWLV"
     gene            6018..7505
                     /locus_tag="VVO74_001807"
     CDS             6018..7505
                     /locus_tag="VVO74_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEU5695793.1"
                     /translation="MLETNDILKLVAEVKKMIADDRVSDLKKDMQVSIDYYNGLHDIG
                     GYRLFFFNNEGQIVEEKNRSNTKIAHQFFTELVDQKVQYLLSNPIEISTEDAELQKYL
                     NEYIDEDFQLMLQELVEGASQKAIEYVFWKKGADNRISFKTADAFKIIPIYDAFYNIE
                     QVIYYYDDEITIENKKKPVTKVQLWTKEEIFYFVQIDNKDLKLDDSIKINPSPHIIAK
                     NNSELFGKSYGQVPFLCLENNRQKKNDLAPIKDLIDDYDLMACSLSNNLIDFDHPIYA
                     VRGFEGDNLDNLVTNLRTKKTVGVGENGGIEVHTVNIPVEARKTKLTIDKEAIYKFGM
                     GFDSSQTGDGNITNVVIKSRYSLLDLKCNKTEVRLRKVIKRMLKLIVENINELHEKAF
                     DASTITIKITRDVMVNKTDNATTEKIEAETKKILVDNIMTASTRLDDKTVLKTLCEIL
                     EVDFAEVERLFDEQGYKGDFNQNSEVTDDGVEQVSAGNRVPAEES"
     gene            7459..9030
                     /locus_tag="VVO74_001808"
     CDS             7459..9030
                     /locus_tag="VVO74_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695794.1"
                     /translation="MNRFQREIEFLLKKADKSTDRRLYDLYIDTIKDLKKSLLVDYQR
                     IGELKSSEKLKLSQMTALLEQLERSSSELKKELKNEITGHLIHTGQIAYNELFYEYET
                     SYAGINFALLKEDELRTIIETPIANFKLSERLDDGVVERLKSNIKDDLNRVFLNGDSY
                     AKAAARLAEQGYSSYRRAIMITRTEAGRVQAVAREKAQVEARNLGIDFDKVWVATLDG
                     RTRHNHAELDGAKADKDGYFEINGLRTKQPHMFGVASEDVNCRCRTISRLKDDKTPLL
                     RRDNETGEIVEYRNYQEWEKATLERRLATNERKSIDNRLYRKYHIDNSQTKDISTETL
                     KSVNESLDKLMQKHKGIKPYLKKVTFTDSLADTTASAGIRFNKGKAEFSIKLNHEHFK
                     KPETIQKLIDVRVADGEWTPKNGINGILEHEVIHLREYKAIVKRYGTLNGTNTEAQKS
                     KIRKAFANNELPKEIKETALKNLQIPDENAIIESRLGRYATENAAEFVAEAYSDASNS
                     EIAIEVRRLVDKKWR"
     gene            9036..9227
                     /locus_tag="VVO74_001809"
     CDS             9036..9227
                     /locus_tag="VVO74_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000909062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695795.1"
                     /translation="MLISPSLQLGSRVERLDDGYWHVKSEYKATWTKGDQDLLDRCNE
                     TIKEYRKDRSKFVFDDDIE"
     gene            9390..9929
                     /locus_tag="VVO74_001810"
     CDS             9390..9929
                     /locus_tag="VVO74_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HEU5695796.1"
                     /translation="MKRDFLVGLGLSDDVINQIMVEHGKSVQGVQSKLDEAESKLEEA
                     NSTLDTLKQSNKDNEDLQNELKTYKEKVSQLEADAKETTKKQTIKDALGNVKATDVDY
                     LMYKLGDVELAEDGSIKDLDSKIKDLQTNYPTFFQISEPEQPDNGFKSLGGADIPPGG
                     KIDPNQSMANEFSQALGLK"
     gene            9948..10865
                     /locus_tag="VVO74_001811"
     CDS             9948..10865
                     /locus_tag="VVO74_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695797.1"
                     /translation="MPNTLEYSKIFQPALDKQIVQESTTGWMEVNSKLVQYNGGNEVK
                     LPSIVMDGLADYDRNTGYVDGAVTLKWETYKLTQDRGRKFQLDAMDVNETNFVATAGT
                     IMGEFQRTLVVPEIDAYRYSAIASKAIAAEQNRAATITDTNILTELLKDIAKVKEVVG
                     NTSKLKIVMSETMLINLGLDDKAAKRMSTVNNAAAGEVATVITKIDGHEITTTQQSLL
                     QTAFKFNDGKTSGQEKGGFVKDSSAKAINWLIIAENAPIAVSKTDTVRVFDPITNQRA
                     NAWDMDYRKYHDIWIPKSKEKSIFVNTVA"
     gene            10876..11103
                     /locus_tag="VVO74_001812"
     CDS             10876..11103
                     /locus_tag="VVO74_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695798.1"
                     /translation="MRKFKRLNVIKETDSDLVADRLLEEGFEEIMGDNEPEGLSRDNI
                     KAQLDAAGIEYAKNAKTEILLEILEASKPGE"
     gene            11136..11666
                     /locus_tag="VVO74_001813"
     CDS             11136..11666
                     /locus_tag="VVO74_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695799.1"
                     /translation="MIISLDEALKLDATATQETCDGLETMVRKLTNNNFQLIKFRLRD
                     LKLSENTIKSSSGRMDVFRPGDTIEINGTDYNDGLYIVKSVSDSVITVHGEFIAEINS
                     GAIATKINYPADVLAGVKKLIAYDVKMRDKVGIKSETIARWSVTYYDVTAAESSEGYP
                     VSLLGFLNKYKKLRWS"
     gene            11663..11971
                     /locus_tag="VVO74_001814"
     CDS             11663..11971
                     /locus_tag="VVO74_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEU5695800.1"
                     /translation="MMMAFNLLKPTSNGENELGQEIFEHKQVAVFFGYMDMLDGSEST
                     DKLAYIADSTHVILTKGRTVNAEIEDKIEVNGKTYEVTYVDDPVNIGHHLEIYVKGAH
                     "
     gene            11971..12378
                     /locus_tag="VVO74_001815"
     CDS             11971..12378
                     /locus_tag="VVO74_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEU5695801.1"
                     /translation="MKFVDNSTTVKRELERAAIRGLIKAAMLVEAQAVLLVPVGETGD
                     LRGSIGYKVNESELVAYVGTNCEYAIYVEFGTGDFAENGNGRKGGWVYRTPKGEVFFT
                     YGMPPQPYLRPAFRENQKAIREILANCLKELGG"
     gene            12379..12747
                     /locus_tag="VVO74_001816"
     CDS             12379..12747
                     /locus_tag="VVO74_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695802.1"
                     /translation="MKEVIKTILKELKSLNTESYYIKNSAQVVKYPYAVFSLSLTNID
                     QHADSCYMDVDIFCNEGLDQVQIETLSESIKMHFRHFNKILEDCYMRMQFQSMQTVQT
                     NLDNLQRRNLRFYIKIDWRK"
     gene            12748..13365
                     /locus_tag="VVO74_001817"
     CDS             12748..13365
                     /locus_tag="VVO74_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695803.1"
                     /translation="MGKTAVKRTGYSANTPKHYLINAGAIYKNLEWNATGGEGSKGQW
                     EGELLGATAGGNKVTIEQNYRVIDIDGVFTPAVGQKILESQTAKLETNVKELTAENIR
                     LSINGKIADSDGVDAPTGYKVISGKAKLENTDYIKNLGIVGTMSGTDDPIIIIIDNAL
                     CTSGLDFETKDNDEAVISMTFEAHANEGQVDDLSLPCRIYFPNIN"
     gene            13375..13803
                     /locus_tag="VVO74_001818"
     CDS             13375..13803
                     /locus_tag="VVO74_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695804.1"
                     /translation="MSEKLEMCELNGGDIFTMLSIIGKLDIKEEVVALIERQYATGKN
                     VVPLADHQKKKPTKKEQEEASLSYQKRGMVLATDIGFAILKHVGDAKNEVNKFLADLT
                     STSQKEIESLNMASYTKLLFDFGKKAELKDFFQSIASLLD"
     gene            13899..14108
                     /locus_tag="VVO74_001819"
     CDS             13899..14108
                     /locus_tag="VVO74_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695805.1"
                     /translation="MYLLDEQDKEELTDIWKSKEINMSLADFIKKYSKKSYIEKQSKK
                     QQTIKKDNEAIALAESILKLPGKGG"
     gene            14113..>15074
                     /locus_tag="VVO74_001820"
     CDS             14113..>15074
                     /locus_tag="VVO74_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695806.1"
                     /translation="MNVFELFGKIGINNKPANKAIDETTGKAEGAHSKLSVIFGKIGN
                     LAVKAGKVMATGLAVGITAISSLIGAAVKNYAEYEQLVGGIETLFGAGGKSLEEYAQS
                     VGKSVDDASSEYKKLINAQEDLLNKSKIAYKTAGLSANEYMETATSFSASLIQSVKGD
                     TEKAAKLADQAIIDMSDNANKMGSSMESIQNAYQGFAKQNYTMLDNLKLGFGGTKEEM
                     QRLLDEAGKISGVKYDISSFADITEAIHVMQVKMGIAGTTSKEAASTISGSLGMVKAS
                     WENFLTGMSDPEQDFEDLVDSLTESIGIALGNIIPKLVQALPRV"
BASE COUNT         5293 a         2423 c         3369 g         3989 t
ORIGIN      
        1 agagatatga gcttaaaagc aggtgatttt gtgaaaattt taaaaatgga gaattcttta
       61 aaatcgtaca aatcaaaaag atctacggag actgtattga aaccagtcac ggactttata
      121 acagaactac acttgcaagt cgattagatg gcaggtgtat tatatctgga attgtgagtt
      181 gggaggacca gcatggagtg gacggattgg gtggacttgg aacctgaaac caaaacggac
      241 atcaaaacca agattgaaaa tgatggatac acttttccac actacgacaa gaaaaacaat
      301 ggcgtcaagt acgtcatttc tacaatggac atcaagcgag actgtctaag aattggggtg
      361 ccatttgaag atgtgtaccc tttgcaaact acactttttt aacaggagaa aaacaaatgc
      421 aaagaacagc ggtaattaat acgcctttta caatcgtaac aagcaaaaca gaacagaata
      481 tcgaaattgt cgggagctcg ttgtggagtc cagtagcaga atttgtaaaa caagatagac
      541 agctatcact agacgaaaac ggcgacttat ttgagcctga atacaagctg gtgctagaag
      601 ctaagcaatc tgttgatatg attttagata gcgcctatgc agctggagaa tttgccaaag
      661 ataccaaaga agttcagacc ctctttaaat ttattgaaga aaacaaaaag aatctatttg
      721 aagaattggg attccatgga gttttgctat gaagcttgtc ctgaacattg agcctaaacc
      781 tcaatcacgg ccaaggtttg caagacgtgg gagttttacc acgacttacg aagacaagga
      841 catgaaagcc tggcgcaatc attgccagtt gctcattgct aatcagtaca tgggccagcc
      901 tcttcttgag ggagctttga gggcaaaggt tagattttat atcaaacctc ctcagtacat
      961 ttctaaggcc aagaagaacc agcaggccct cctggatgag attatccctg taggcaagaa
     1021 gcctgacatt gacaactacg aaaaagccct atatgacagt atgtcaggga ttgtcttcca
     1081 ggacgatggt cagatagcgc tacatgatgt aggcaagttc tacagtctaa atccacggat
     1141 agaggtagag gtggaggtta tggaacccct gagtatttaa agaaatgagg agcagatgca
     1201 atcctgattg gctcgtactt tgtaagctgc ggtcacgaat ttggagacct ggaaagccat
     1261 aagataagtt aaaggagcag gaagatgaat aagcaggagt tgattggaag aattaaacgt
     1321 ttagatgaat catacttaaa aacggaattt gttttaaaat taatcgaaca actagacgaa
     1381 ccaaaaccag tcaaagttcc gcagtttgtg gcggaatata tcgagtatgc gaaaaacaac
     1441 tattgggatt tacaagattt atttaagttt atagacgatg aagaaaataa gaatttacaa
     1501 agatggtttt atcacgaatg tgaacaagaa acacttgcac tagcttggct tttcggctac
     1561 gaggtcgagg gagaaaagcg gtattttgtg aagatgaaag ggatcgcaaa atacaaaaat
     1621 tatttagtat ttggtgaaat atcgagaaca tggttttttg ctagtgttgg aagcaatgat
     1681 gtgacattca cacacaccag caaagaacta gaagaagctg gtttcggctg ggtgtttaat
     1741 tgtgagggga tagaagtcga ggaggtggag tgatggaaga tactatctgg ctagaatgga
     1801 ttgctgaggt tatggcaact aagcctgtcg gtaacgaatt gctagaaagc caacgtggtc
     1861 aagaagtagt tgatttgcta ttggatttgg agagcaatga ctttaattgg catcgaggcg
     1921 atgctgacac tttctggata gatgctcaga tgtgcatcaa gtatcaactt tcaaatgcgg
     1981 agattaaatt cttagctaaa caacaaccag gtgttgtgaa ttataagaag cacgcaaaag
     2041 aaagaaatgc ttattcagag atgatgagag gtcttgagaa gttgaaagaa cttaactttc
     2101 cagaaatata taatcattcg ttatctccag aagaagaaaa gaaaaaattt gaagaagaaa
     2161 tggcgattga acaaaagtac atatcgcctt atcaaaaatt agatgaactt gaaaaacgat
     2221 tttttgaaaa tcaattttta tttggtcaaa aagtgatgga agctgcaatg aaaattgtat
     2281 caagcgaaaa gaaaataact gttgataatt ttttcaatat tggaagtcat cgaattaaat
     2341 tcacagttga ggaggtcaca aattgaaaaa tacactaatt cgcttcttgc ttgcatggtc
     2401 gcttatcgct acttgcttgt tattcatgca acgtgaagca cagaaaccct tgcttgttta
     2461 ttacactgat agcaagtatc agatcactgg caaggtggaa gaaaaacgaa aaatcggaaa
     2521 tctattcact atcacggtaa acggtaacgt gtttgtggtg aatgagcaga aatataaaaa
     2581 tattgaaata ggagataata tcgaattatg aacacaatag acaaagtcaa acaatggttt
     2641 attgaccgtg atttagaaaa cggaggagaa tgatggctaa agatatttta acggatctag
     2701 catttgagaa ttttcacaaa tgtatgggaa ttactgattg gaaagaatct gatgaagtaa
     2761 ttcttgttag cttggctaac aaagaacaaa ttgagtcaga tgaaagttat cgttcagccg
     2821 gaaaatgtaa ttatcttggc aaacgaatct gtatcttttg cacacaggta aagaaaaata
     2881 attacattac gctacataaa tcttttttag aaaaagttat taagacaatg gaatcattta
     2941 aagatgtgga ggaaaagtaa aatgaaaatc aaaaaaattg tagcagttat ttcagtatta
     3001 agtgcattgt tattattaac tgcttgccgt gaaagcgaaa aggtttctta taacgtcagt
     3061 caagaagcag ataacttcaa cattgttcgt cgcgtggcag ttattaacac tcgaacagat
     3121 aaagttgagt ttgaggtcat tggacgcatt tctgtagaga cggaagcaaa cgaaggcaaa
     3181 cgtcttgaaa tcttagttga gactgcaaag ggcgtttaca agaaacacat ggtaaatcta
     3241 acaagttgga atatgtatgt cgtagaagac cttgaaggcg ctgaagtaga tcagtacaaa
     3301 tatgaggtca actacatgcc tgaaagtatt atcccgttta aagtaacgaa aaaagactaa
     3361 ataaaaaagc caagacactc tctgtctcag ctaatagtta tcgcaaagac tatgatacca
     3421 caaaaggaga tagagagtga acaaggctaa agagctcttg aaagagctac aggatctgga
     3481 tatagatatc caaagccgta tagacgaaat taacgagctt gaggcaggtt tgctctcaag
     3541 ccctaagtgg actgatgtca aagtccaagg tggtcaagct agaaaagttg atgacgtcta
     3601 tactcagctt gttgtaatga aagaggctat agaacaggat acgaaagagg ttatcgacag
     3661 aaagcttgaa ttaggtagaa tgatcaacag gcttaaaaat ccaaagcata gaactatttt
     3721 gagaaagacc tacatcaata aaatgtacgt cgatgacatc tgtgagagta tgggaggcat
     3781 gagctctcct acttattatc gcttgaagaa acaggcggta aatgagcttg atgtcattct
     3841 ttcggaattg atagtgaatg atagtaacgg tacaggcatg aagtctaaaa tctgttagaa
     3901 tggtagtatc aagaattgaa caaaggcacc ttaggcgacg acctagaaaa gcttctgaaa
     3961 aactgctggc ttgggttacc agtggcgata gagtaggatg ttttaatatc gcaaaaaatg
     4021 actacaaaaa ataaaaaaca aatgtagtat ctaaactagc aaggttgtag tcgccttgca
     4081 gtaaggacat agctcaattg gtagagcggt aggttttcac cctattggtt gcaggttcaa
     4141 gtcctgttgt tcttatgaga ggtcttacaa agggtcacac attgtgtggc tttttgtgtt
     4201 gtaaaaaacg ggtggtgatg atattggcga agaaaacgaa gcgtggtaga ccgaccaaga
     4261 tgacccaagg gacactccgg aaattagaag agttgtttgt gagaggttta agtgacgaag
     4321 aagcctgtct tctagctgat ataggaacca caactctcta tgattactgc aaggaaaatc
     4381 ctgaattttc ggagcgaaaa gagctactta agcaacgcgt taaaatacga gctaaactta
     4441 atatatcaaa agcaattgaa gacggtgata cagacttgtc aaaatggtac ttgagcgtcg
     4501 agataatgat tttaaggcaa aacaagcagt cacacacggc ggagaaatag ctgttaatca
     4561 agtaaatcca ttcgctggtc tatcaactga agaattaaga aagttaattg ctgatggata
     4621 aagcagcact caagaggcaa gcgcagctgg aacttgcacg tcgtaatttt ttttattact
     4681 gccaacttat ggcaggagat ttctacaagt cagaaagaat ctatctaaaa cagttgtgtg
     4741 acagttttca aaacttcatg tctgacgacg agcacaatgt gttgatcatc aatatcggcc
     4801 cgcgccatag taaatcgcgt acggctggaa tgtttgtcca atggttgttg ggaaatgata
     4861 acacaaagaa aattatgaca ggctcataca atgatacatt gtcaacagta ttttcaaaat
     4921 ctgttcgaaa cgctatccag gaagagaagg cagatgactc catcacagtc ttttctgaca
     4981 tattcccgga taccaaaatc aagcgtggcg atggagctat gaacctgtgg tcactggaaa
     5041 aggggtataa caattacttg gcgacctcac caggcgggac cgcaacaggt ttcggcgcgg
     5101 atgtcattat catagatgac ttgattaaga gcgctctgga agccaataat gcgaatatcc
     5161 tagagggtca ttgggagtgg ttcacaaata ccatgctatc gcgttttgaa gaaggtggca
     5221 aactgattat catcatgacc cgctggcatt ccgaagacct tgctggcaag gccttgagca
     5281 agctacccga atctgggtat agcgtcaagc atatcagtat gcggacctac gatgaagaaa
     5341 cagacactat gttgtgcgag gatgttctga gcaaagagtc ttatttccgc aaggtcaaag
     5401 ctatgggtgc cgatattgct tcggctaact atcaacaaga acctatcgac attaaaggta
     5461 gattatatag cgagtttaaa acctatgtag atagaccgat atttaagcgt attagcgcct
     5521 atactgatac ggcagatacg ggtaaggact atctagctag ttatatctac ggagaaacga
     5581 tggataagga agcttatatc ttagatatct tgttcacgaa ggagccgatg gaagtgacag
     5641 aacctttatt agcgaggaaa ttagtcgaga acgaggtaaa tctatgctgg attgaatcca
     5701 ataatggtgg tcgtggtttt gctcggaatg tagaacgatt gatgagagaa aatcatggta
     5761 caaatcaaac aacggtcaaa tggttccatc agtcaaaaaa taagcaggct cgtattttaa
     5821 caaatgcaac gtggttaatg gaacatgtct attttccaga agggtggcgt aaccgttggc
     5881 cagagttgta taaaagtctt atgacctatc aaagggaggg tagaaatgct catgatgatg
     5941 cgcaagatgc tttgacaggt atagcagaga aaatcacagc taattcgagc tggcttgtat
     6001 agtgtatagg aggaataatg ttagaaacga atgatatact aaaactagtt gctgaagtaa
     6061 aaaaaatgat tgctgatgat cgtgtaagcg atctaaaaaa agatatgcaa gttagtattg
     6121 attactacaa tggattacat gatattggag gttacagact tttctttttc aacaacgaag
     6181 gtcaaattgt agaagagaag aatcgaagca atacaaaaat tgctcatcag ttctttactg
     6241 agttagtgga tcaaaaagta caatacttgc tttcaaatcc tattgaaatt tcaacagaag
     6301 atgctgaatt gcaaaaatat ttgaatgagt atatagatga agattttcaa ctcatgttac
     6361 aagaactcgt tgaaggagca agtcaaaaag ctattgagta tgttttttgg aaaaaaggtg
     6421 cagacaaccg tatcagtttt aaaactgctg acgcttttaa aataataccg atttacgatg
     6481 cattttacaa cattgaacaa gtaatctatt attacgatga tgaaattacg attgaaaata
     6541 agaaaaaacc cgtaactaaa gttcagctct ggacaaaaga agagattttt tattttgtgc
     6601 aaatcgacaa taaagattta aagttagatg attctatcaa aattaatccc tctccgcaca
     6661 taatcgcaaa aaacaatagt gagctatttg gaaaaagtta cggccaggtg ccattcctat
     6721 gtttagaaaa caatcgacaa aagaaaaatg atttagcgcc tatcaaggat ttaatcgatg
     6781 attatgattt gatggcatgt tctctatcta ataacttaat cgactttgat cacccgattt
     6841 atgctgtcag aggttttgaa ggtgataacc ttgataacct agttactaat ttgagaacaa
     6901 aaaaaactgt tggtgttggg gagaatggag gtatcgaagt tcatactgtt aatattcctg
     6961 ttgaagcacg taaaacaaaa ttaactattg ataaagaggc catctataaa tttggaatgg
     7021 gcttcgatag ttctcagaca ggtgatggaa atatcactaa tgttgttatc aaatcgagat
     7081 acagcttact tgatttaaag tgtaataaaa ctgaagtccg actgcggaaa gtcattaaga
     7141 gaatgctaaa acttattgta gagaatataa atgagctgca tgaaaaggct tttgatgcgt
     7201 cgacaatcac tataaaaatt actcgcgatg ttatggttaa caagacggac aatgcgacaa
     7261 ctgagaagat tgaagctgag actaagaaga ttcttgtgga taacatcatg acagcttcta
     7321 cccgattgga tgataagact gttctaaaaa ctttgtgtga aatcctagaa gtggattttg
     7381 cagaagtcga gcgcttgttt gatgaacagg gttacaaagg agatttcaat cagaattcgg
     7441 aggtgacaga tgacggagtt gaacaggttt cagcgggaaa tagagttcct gctgaagaaa
     7501 gctgataagt caacggatag acggctctat gacctctaca ttgatacgat taaagacttg
     7561 aaaaaatcct tgctggtaga ttatcagcga atcggagaat taaaatcgtc agaaaaactc
     7621 aaattgagtc aaatgacagc acttttggaa caactggagc gatcctctag tgaactaaaa
     7681 aaagaactta aaaatgaaat cacagggcat ctaatacata cgggacagat agcttataac
     7741 gagttattct atgagtatga gactagctat gctgggatta actttgctct tctgaaagaa
     7801 gatgaactca ggactattat agaaacacct atcgctaatt ttaaattatc cgaacggtta
     7861 gatgacggag ttgtcgaacg gttaaaaagc aatatcaagg atgatttaaa ccgagtgttt
     7921 ttgaacggag atagttatgc aaaggctgct gctagactag cggaacaagg gtatagttcc
     7981 tatcgtagag caattatgat tacccgaaca gaagctggac gggttcaggc tgttgccagg
     8041 gagaaagcac aagtagaagc tagaaatctg ggtattgatt ttgacaaggt ttgggtagct
     8101 actctggatg gtcgtactag acacaatcat gcagaattgg acggtgccaa ggccgacaaa
     8161 gacggttact ttgagattaa cggtctgcgg accaagcaac cgcatatgtt cggtgttgcc
     8221 agcgaggatg tcaactgcag atgtcggaca atatcaaggc ttaaagatga taaaaccccg
     8281 cttttaagac gcgataacga aactggcgag attgtcgaat atcggaatta tcaggagtgg
     8341 gagaaagcca ccttggaacg cagattggcg acaaatgaga gaaaatcaat tgataatcgc
     8401 ctgtatcgta aatatcatat tgataacagt caaaccaagg atatatcaac agaaactttg
     8461 aaatctgtga atgaaagcct agacaaattg atgcaaaagc acaaaggtat caagccgtat
     8521 ttaaaaaagg taacttttac tgatagctta gctgatacta ctgcaagcgc tggaataaga
     8581 ttcaataaag ggaaagctga attttctatc aagttgaatc atgaacattt taaaaaaccg
     8641 gaaacgattc aaaagttaat agatgttcgt gtcgcagatg gtgaatggac ccctaagaat
     8701 ggtattaacg gcattcttga acacgaagtt atccacttgc gagaatacaa agcaattgtc
     8761 aagagatacg ggactttgaa cggtacaaat acagaggctc aaaaatctaa aataagaaag
     8821 gcatttgcta ataacgaact accaaaagaa atcaaagaaa cagcgctaaa aaacttacaa
     8881 attcctgatg aaaatgctat aattgaatca agactaggta ggtacgccac agaaaatgca
     8941 gctgaatttg tagctgaagc atactcagac gcaagtaatt cagagatagc aattgaagtg
     9001 agacgattag ttgacaagaa atggaggtga cctttatgct cattagccct agtttacaat
     9061 taggaagcag agttgaacgt ttggatgatg gctattggca tgtaaaatct gagtacaaag
     9121 ctacttggac gaaaggtgac caggatttgt tagaccgatg caacgaaaca atcaaagagt
     9181 atcgaaaaga taggtctaaa tttgtttttg atgacgatat agaataagca cctagagaag
     9241 tctaagtgct tttcttatat cctaaccgta tggaatcccg tacggttttc tttttgccca
     9301 aaaaactcgc ccggcatggc gttaaactgt ttaacatatt tcaaattctc gtggtcgtca
     9361 cacgttaact agacgtagaa ggagaacgta tgaaacgtga ttttttagta ggccttggat
     9421 tgtctgatga cgttatcaat cagattatgg ttgagcacgg gaagtctgtt caaggtgtgc
     9481 agtcgaagct tgacgaagca gagagtaagc tcgaagaagc taacagcacg ctggacacgc
     9541 tgaaacagtc taataaggac aatgaagatc tgcagaacga actaaaaacg tacaaagaga
     9601 aggtgtcgca actggaagct gatgcaaaag aaacaaccaa gaagcagacc atcaaggatg
     9661 ctttgggcaa cgtaaaagca acagatgttg attatctcat gtacaaacta ggcgatgtag
     9721 aattggcaga ggacggtagc attaaggacc tcgacagtaa aatcaaggac ttgcagacaa
     9781 actacccgac attcttccaa atttcagagc cagaacaacc agataatggt tttaagtctt
     9841 tgggtggagc tgatatccca cctggtggga aaatcgaccc aaatcaatct atggctaatg
     9901 aatttagcca agcattagga ttaaaataaa aaaggagaaa gtaaattatg ccaaatactc
     9961 ttgaatactc aaaaattttc caacctgccc tggataagca aatcgtacag gaatcaacaa
    10021 cgggttggat ggaagttaac agtaagttag tccaatacaa cggtggtaat gaagtcaagc
    10081 ttccatctat tgtgatggac ggacttgctg attatgatcg taatacaggt tatgttgacg
    10141 gtgctgtaac actcaaatgg gaaacctaca aacttacaca agatcgtgga cgtaagttcc
    10201 aattggatgc tatggacgtt aatgaaacaa actttgttgc aactgcagga actatcatgg
    10261 gtgaattcca acgaactctg gtagtaccag aaatcgacgc ttaccgttac tcagcaatcg
    10321 catctaaagc tattgcagcc gaacaaaatc gtgcagcaac aattactgat acaaacatct
    10381 tgaccgagct tttgaaagat attgcgaaag tgaaagaagt tgtcggaaat acttctaaac
    10441 taaaaattgt tatgtctgaa accatgttga tcaatcttgg acttgacgat aaagctgcta
    10501 aacgtatgtc gacagttaat aatgcagctg ctggagaagt ggcgactgtt attactaaaa
    10561 ttgacggtca cgaaatcact acaactcagc agtcattact tcaaactgca tttaagttta
    10621 atgacggtaa aactagtgga caggagaaag gtggctttgt aaaagactcc tctgctaaag
    10681 ctattaactg gcttatcatt gctgaaaatg cacctattgc agtgtctaaa acagatactg
    10741 tgcgagtatt tgatccaatt acaaatcaac gtgcgaacgc ttgggatatg gactatcgta
    10801 aatatcatga tatttggatt cctaaatcta aagaaaaatc aatttttgtc aatactgtag
    10861 cttaggaggt ttcttatgcg caaatttaaa cgactgaatg tcattaagga aacggatagt
    10921 gacttggtag ctgacagact tttagaggaa gggtttgaag aaatcatggg tgacaatgaa
    10981 ccagaaggtc tgtctcgtga caatatcaaa gctcaattgg atgcagctgg catcgagtat
    11041 gctaaaaacg caaaaactga aatcttgctt gaaattttag aagcatcaaa accaggagag
    11101 tagtcatcta ctctcctttt taatcggagg tatgtatgat tattagccta gacgaagcac
    11161 taaaacttga cgcaactgcc acacaggaaa cttgtgacgg tttggaaact atggttcgaa
    11221 aattgaccaa caacaatttt caattgatta aattccgact ccgagacttg aaattgtcag
    11281 aaaacacaat caagtcaagt agtgggcgta tggatgtatt ccgccctgga gacacaatcg
    11341 aaattaacgg aacagattac aatgacggcc tatacatcgt caagagcgtt tctgatagcg
    11401 tgattactgt ccatggagaa tttatcgcag aaatcaattc aggagccata gcaacgaaaa
    11461 ttaactatcc agcggatgtt ttggccggtg tgaagaagtt gattgcttac gatgtaaaaa
    11521 tgcgtgacaa agtaggtatc aaatccgaga caatagcacg ttggtctgtg acgtactacg
    11581 atgttacagc agcagaaagt tcagaaggct atccggtcag tctacttgga ttcttaaata
    11641 agtacaagaa actgaggtgg tcatgatgat ggcatttaat cttctaaaac ctacctctaa
    11701 tggcgagaat gaacttggcc aagaaatctt tgaacacaag caagttgctg tgttttttgg
    11761 ttatatggat atgctggacg gtagtgaatc gaccgacaaa ctagcctata ttgcagatag
    11821 tactcatgtc attctaacaa agggcaggac agtcaatgct gaaatagaag acaagattga
    11881 agttaatgga aaaacctatg aagtgaccta tgttgatgat ccggtaaata tcgggcatca
    11941 tctggaaatc tatgttaaag gagcccattg atgaaatttg ttgataattc aacgactgtc
    12001 aaaagagagc ttgaacgtgc tgcaattaga ggcttgatta aggcagctat gttggtagag
    12061 gctcaagctg tgttactggt ccctgttggt gaaacaggcg atttgcgagg tagtattggc
    12121 tataaagtca atgaaagcga gctggtagct tatgtcggca ctaactgtga atatgcgatt
    12181 tatgtcgaat ttggtactgg tgattttgca gagaatggga atggtcgtaa aggtggctgg
    12241 gtgtaccgta cgcctaaagg agaggtcttt ttcacttatg gaatgccacc acaaccgtac
    12301 ctgagaccag cttttagaga aaatcaaaaa gctataaggg agatattagc aaactgcttg
    12361 aaagaattgg gagggtagat gaaagaagtt atcaaaacaa ttctgaaaga attgaaaagt
    12421 cttaatactg agagttacta catcaagaac agtgctcagg ttgtcaaata tccttacgca
    12481 gtcttttcat taagtctgac taacattgac caacacgcag acagctgtta tatggatgtg
    12541 gatatttttt gtaacgaggg actggatcag gttcaaatag aaacattatc cgaaagtatc
    12601 aaaatgcatt ttagacattt taacaaaatc cttgaggatt gctacatgcg aatgcaattc
    12661 caatcgatgc agacagtaca aacaaatctg gacaacctgc aacgtcggaa cttgcgtttt
    12721 tatataaaaa tagattggag aaaataaatg ggaaaaactg ctgtaaagcg aacaggctac
    12781 tcagccaata caccaaaaca ttatttgatt aatgctggtg caatctataa aaatttagaa
    12841 tggaatgcaa ctggtggtga agggagcaaa ggccaatggg aaggtgaatt gcttggtgca
    12901 actgctggag gtaataaggt tacaattgaa cagaattacc gagtaattga tattgatggt
    12961 gtgtttactc ctgcagtagg ccaaaagatc ctcgaaagtc aaacggcaaa actggaaact
    13021 aatgtcaaag aattgacagc cgaaaacatt cgattgtcaa tcaatgggaa gattgcagac
    13081 tcagacggtg tagatgctcc gactggatat aaagtgattt ctggtaaagc gaaattagaa
    13141 aacactgatt atatcaaaaa cttaggaatt gttggaacga tgtcaggaac cgacgatcca
    13201 atcattatca ttattgataa tgctttgtgc acatctggct tagactttga aacaaaagac
    13261 aatgatgagg ctgtaatctc aatgactttc gaagcgcatg ctaatgaagg tcaagttgat
    13321 gatttaagct taccttgtcg tatttatttc ccaaatatca attaggaggt ttttatgtct
    13381 gagaaattgg aaatgtgtga gttgaatggt ggagatatct tcactatgtt atctattatt
    13441 ggaaaactag atatcaaaga agaagttgtc gcactgattg agcgtcaata tgcgactggg
    13501 aaaaatgtag ttcctttagc tgatcatcag aaaaagaaac ctaccaaaaa agaacaagaa
    13561 gaagcgagtc ttagctatca aaaacgtggc atggtgttag caacggatat tggattcgct
    13621 attttaaaac atgttggcga tgctaaaaat gaagtcaata aattcttggc cgacttgaca
    13681 agcacgagtc agaaagaaat tgagtcatta aacatggcaa gttacacgaa gctgcttttt
    13741 gattttggga aaaaggcgga acttaaggat tttttccaat ctattgcttc gctattggat
    13801 taggattaaa taagctaaga gatatacttt tcaagaggta cgggaatcca gagcaacttt
    13861 tagaaaatca aaatctaaaa gaagctttgg atttttttat gtatttactt gatgaacaag
    13921 ataaagaaga actaacagac atttggaaat caaaagaaat aaatatgtct ttagcagatt
    13981 ttatcaaaaa atactctaag aaaagttata ttgaaaaaca aagtaagaag caacaaacaa
    14041 taaaaaaaga taatgaagct atagctttgg ctgaatctat cttgaaatta ccagggaaag
    14101 gaggttagaa aagtgaatgt atttgaacta tttggaaaaa tcggtataaa taataaacct
    14161 gctaacaaag ctatcgatga aacgactggg aaagcagaag gtgctcatag taaactatca
    14221 gttatttttg gaaaaattgg caatctagct gtaaaagctg gtaaagtgat ggctactgga
    14281 ttagcagtcg gtattacagc aataagcagt ttaattggcg ctgcagttaa aaactatgct
    14341 gaatatgagc aattggtagg cgggatagaa acacttttcg gcgcaggcgg aaaatctctt
    14401 gaagaatatg ctcaatcagt tggtaagagt gtagatgatg cgtctagcga atacaagaag
    14461 ctaataaacg cacaagaaga tttgttgaat aagtctaaaa tcgcatataa gacagcaggc
    14521 ctatcggcaa atgagtacat ggaaactgcg acatctttct ctgcctcttt aatccaatca
    14581 gtaaaagggg acactgaaaa agctgctaaa cttgcagatc aagctatcat cgatatgtct
    14641 gataatgcta ataagatggg gtcatcgatg gaatctatac aaaatgctta tcagggattt
    14701 gctaagcaga attatactat gctggataac ttgaaattag gttttggtgg cactaaagaa
    14761 gaaatgcagc gattgcttga tgaagcggga aaaatcagcg gtgttaagta tgacatttct
    14821 tcatttgcag atatcaccga agctatacat gtaatgcaag taaaaatggg aattgcagga
    14881 acaacttcga aggaagctgc ttcaacaatc tctggttctc tcggtatggt aaaagcaagc
    14941 tgggaaaatt ttttaacagg catgtcagat cctgaacagg attttgagga tttagttgat
    15001 tctttaactg aatcaattgg gattgcatta ggtaatataa tcccaaaatt ggttcaagct
    15061 ttaccaagag tcat
//
LOCUS       DAVHKZ010000044        14687 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000044 DAVHKZ010000000
VERSION     DAVHKZ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14687
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.044"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..216
                     /locus_tag="VVO74_001821"
     CDS             <1..216
                     /locus_tag="VVO74_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5695807.1"
                     /translation="QTPRKSSKFKPLTVEDKTYNHALSKERSKVENIFAKVETFKMFS
                     TTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            407..2698
                     /gene="pcrA"
                     /locus_tag="VVO74_001822"
     CDS             407..2698
                     /gene="pcrA"
                     /locus_tag="VVO74_001822"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU5695808.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDSDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSISDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2741..3421
                     /gene="radC"
                     /locus_tag="VVO74_001823"
     CDS             2741..3421
                     /gene="radC"
                     /locus_tag="VVO74_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU5695809.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3418..4107)
                     /locus_tag="VVO74_001824"
     CDS             complement(3418..4107)
                     /locus_tag="VVO74_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU5695810.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQNSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4125..4766)
                     /locus_tag="VVO74_001825"
     CDS             complement(4125..4766)
                     /locus_tag="VVO74_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU5695811.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTTILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4849..5064)
                     /locus_tag="VVO74_001826"
     CDS             complement(4849..5064)
                     /locus_tag="VVO74_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU5695812.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5072..5419)
                     /locus_tag="VVO74_001827"
     CDS             complement(5072..5419)
                     /locus_tag="VVO74_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU5695813.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5424..6539)
                     /locus_tag="VVO74_001828"
     CDS             complement(5424..6539)
                     /locus_tag="VVO74_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU5695814.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPKNQEITAQQIQKALRDDTILVSTMFVNNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6549..7508)
                     /locus_tag="VVO74_001829"
     CDS             complement(6549..7508)
                     /locus_tag="VVO74_001829"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU5695815.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7621..8190)
                     /locus_tag="VVO74_001830"
     CDS             complement(7621..8190)
                     /locus_tag="VVO74_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU5695816.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKRVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDVENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8318..8989
                     /locus_tag="VVO74_001831"
     CDS             8318..8989
                     /locus_tag="VVO74_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU5695817.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8973..9791
                     /locus_tag="VVO74_001832"
     CDS             8973..9791
                     /locus_tag="VVO74_001832"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU5695818.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9788..10684
                     /locus_tag="VVO74_001833"
     CDS             9788..10684
                     /locus_tag="VVO74_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU5695819.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10728..11702
                     /gene="pta"
                     /locus_tag="VVO74_001834"
     CDS             10728..11702
                     /gene="pta"
                     /locus_tag="VVO74_001834"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU5695820.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(12043..12342)
                     /locus_tag="VVO74_001835"
     CDS             complement(12043..12342)
                     /locus_tag="VVO74_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU5695821.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVISIDFNPAVIDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            12744..13448
                     /locus_tag="VVO74_001836"
     CDS             12744..13448
                     /locus_tag="VVO74_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU5695822.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     misc_feature    13507..13594
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            13630..13944
                     /gene="rplU"
                     /locus_tag="VVO74_001837"
     CDS             13630..13944
                     /gene="rplU"
                     /locus_tag="VVO74_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU5695823.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            13960..14304
                     /locus_tag="VVO74_001838"
     CDS             13960..14304
                     /locus_tag="VVO74_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU5695824.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            14321..14614
                     /gene="rpmA"
                     /locus_tag="VVO74_001839"
     CDS             14321..14614
                     /gene="rpmA"
                     /locus_tag="VVO74_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU5695825.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
BASE COUNT         4322 a         2756 c         3128 g         4481 t
ORIGIN      
        1 caaactccac gtaaatccag caaattcaag ccgctaacag ttgaagataa aacctataac
       61 catgcgctat ctaaggagag aagcaaggtt gagaacatct ttgccaaagt agaaacgttt
      121 aaaatgtttt caacaaccta tcgaaatcat cgtaaacgct ttggattacg aatgaatttg
      181 attgctggta ttatcaatca tgaactagga ttctagtttt gcaggaagtc tattgaggta
      241 ttgagctagt ttatgaaaaa attgggtgaa aagtcgagtg ttttagaaac ccacagtgta
      301 gtattctagt ttcaatccac tatattttgc tactccccgt aaagtttcta ttttccctga
      361 tttctgatat aatagaaata ttgacttcaa gagtaaggaa gagaagatga acgcattatt
      421 aaatggaatg aatgaccgtc aggctgaggc ggtgcaaacg acagaaggtc ccttgctaat
      481 catggcagga gctggttctg gaaagactcg tgttttaacc caccgtatcg cttatttgat
      541 tgatgaaaag ctggtcaatc cttggaatat cttggccatt acctttacca acaaggctgc
      601 gcgtgagatg aaagagcgtg cttatagcct caatccagct actcaggact gtctgattgc
      661 gaccttccac tccatgtgtg tgcgtatttt gcgtcgcgat gcggaccata ttggctacaa
      721 tcgtaatttt acaattgtgg atcctggtga acagcgaacg ctcatgaaac gtattctcaa
      781 acagttgaac ttggatccta aaaaatggaa tgaacgaact attttgggga ccatttccaa
      841 tgctaagaat gatttgattg atgatgttgc ttatgctgcc caagctggcg atatgtatac
      901 gcaaattgtg gcccagtgtt atacaaccta tcaaaaagaa cttcgtcagt ctgaatccgt
      961 tgactttgat gatttgatta tgctgacctt gcgtctcttt gatcaaaatc ctgatgtttt
     1021 gacctactac cagcaaaaat tccaatacat ccacgttgat gagtaccaag ataccaacca
     1081 cgctcagtac caattggtca aactcttggc ttcccgtttt aaaaatatct gtgtggttgg
     1141 ggatgcggac cagtctatct acggttggcg tggtgctgat atgcagaata tcttggactt
     1201 tgaaaaggat taccccaaag ccaaggttgt tttgttggag gaaaattacc gctcaaccaa
     1261 aaccattctc caagcggcca acgaggttat taaaaataat aaaaatcgcc gtcctaaaaa
     1321 tctctggact caaaacgctg atggggagca aatcgtttac tatcgtgccg atgatgagct
     1381 ggatgaggct gtatttgtag ccagaaccat cgatgaactt agtcgcagtc aaaacttcct
     1441 tcataaggat tttgcagttc tctatcggac taatgcccag tcccgtacaa ttgaggaagc
     1501 cctgctcaag tctaacattc cttataccat ggttggtgga accaaattct acagccgtaa
     1561 ggaaattcgc gatattattg cttatctcaa ccttattgct aatttgagtg acaatattag
     1621 ttttgagcgt attatcaacg agcctaaacg tggaattggt ctaggtacag ttgagaaaat
     1681 ccgtgatttt gcaaatttgc aaaatatgtc tatgctggat gcttctgcta atattatgtt
     1741 gtctggtatc aagggtaagg cagcccaatc tatctgggat tttgccaata tgatgcttga
     1801 tttgcgggag cagctagacc acttaagcat tacagagttg gttgagtccg tcctagaaaa
     1861 aacaggttat gtcgatattc ttaacgccca agcgacttta gaaagcaagg cacgggttga
     1921 aaatatcgaa gagtttcttt ctgttacgaa gaactttgat gacaccacgg atgtgacaga
     1981 agaggaaact ggtctggaca aactgagtcg tttcttaaat gacttggctt tgattgccga
     2041 cacagattca ggtagtcagg agacatcaga agtgaccttg atgaccctgc atgctgccaa
     2101 aggtctcgaa tttccagttg tctttttgat tgggatggaa gaaaatgtct ttccacttag
     2161 tcgtgcgact gaagattcag atgaattaga agaagagcgc cgtctagcct atgtaggtat
     2221 cacgcgtgca gagaaaattc tctatctgac caatgccaac tcacgcttgc tttttggtcg
     2281 taccaattat aaccgtccga ctcgttttat taacgaaatc agttcagact tgcttgagta
     2341 tcaaggtctg gctcgtcctg caaatacaag ctttaaggca tcatatagca gtggtagtat
     2401 ttcctttggt caaggtatga gtttggctca ggctcttcaa gaccgtaaac gcggtgctgc
     2461 cccaaaatca atccagtcaa gcggtcttcc atttggtcaa tttacagctg gcgcaaaacc
     2521 agcatctagc gaggcaaatt ggtccattag tgatattgct ctccacaaga aatggggaga
     2581 gggaaccgtt ctggaagttt caggtagcgg tgctaggcag gaattgaaaa tcaatttccc
     2641 agaagtaggt ttgaaaaaac ttttagccag tgtggctcca attgagaaaa aaatctaatt
     2701 ttccatcctt ctcacgaata ataaagtgag gaggattttt atgtacagta tttcattcca
     2761 agaagattca ctattaccaa gagaaaggct ggccaaggaa ggagttgaag cgcttagtaa
     2821 ccaagagttg ctagctattt tactcaggac aggaacacgt caagctagcg tttttgaaat
     2881 tgcccaaaaa gtcttgaaca atctttcaag cctaacggat ttgaaaaaaa tgaccctgca
     2941 ggaattgcag agtttgtctg gtattgggcg tgttaaggcc atagaattac aagctatgat
     3001 tgaactgggg catcgtattc acaaacacga gactcttgaa atggaaagta ttctcagcag
     3061 tcaaaagttg gccaagaaga tgcagcagga attaggggat aaaaaacaag agcacctggt
     3121 ggcactctat ctcaatactc aaaatcaaat catccatcag cagaccattt ttatcgggtc
     3181 tgtaactcgt agtatcgctg aaccgcgaga gattcttcac tatgcaatca agcatatggc
     3241 gacttctctt atcttggtcc acaatcatcc ttcaggagcg gtagcgccta gccaaaatga
     3301 tgatcatgtc actaaacttg ttaaagaagc ctgcgaattg atggggattg ttctcttgga
     3361 ccatttgatt gtctctcatt ctaattactt tagttatcgt gaaaagacag atttaatcta
     3421 aagttcatta acgacatagt caaagagttt tttatctttg ggacgatttt caaaaagaag
     3481 ttctggatgc cattggacac cgagaaaggc gacatcatcc gtactcatga cagcctcaat
     3541 gataccatct ttaggatcat gagccacaac ttttaaattt ggtgctaagt ccttgatgct
     3601 ctggtggtgg aaggagttga tatgagagat ttctccatag atttcttgga gaacggtatc
     3661 tggttctgtt accaagcgtt gagttgtgta ctcaacagaa gaattctgcc aatggtcttc
     3721 gatatcttgg tacaaagttc cacccatggc aacgttaaag agttgggtac cacggcagac
     3781 agagaaaatg ggctttttct gtttaatagc ttccttgatg agggccagtt cgaagatatc
     3841 tctttgaagg tgatagtcat cgctatcaat ggttttgggt tcgccataaa attttggatc
     3901 gacattttgc ccacctgtca agatgagctt gtcaatcaaa ctgatatagt ggcaggccat
     3961 ttcttgatca ccaatcggta ggatgatggg aatccctcca gcatctttaa cgccttcaac
     4021 aaagcctttt gctgcgtagc tcatcatgat gtcatcatct ggatgagttt tttcgtttcc
     4081 tgtaatccca ataactggtt ttttcataaa atgattttcg ctttctaatc ctcttttcgc
     4141 atgaagtaga ggagggtttg gagttcactt gtcaaatcga catactgaac gaccacgtct
     4201 tttggtaaat gcagatggac tggtgaaaaa ctgagaattc ctttcacacc agcatcaacc
     4261 aagagattag caacctcttg tgacttgacg ctgggaacag ttaggatagt agtcttcaca
     4321 tcagcatcct tgattttatc cttgatctga gaaatcccgt aaatgggaat cccgtcagga
     4381 gtttgggtac cgacttcagg atggtcgtct aggtcaaagg ccatgataat cttcatcttg
     4441 ttacgttcgt ggaagcggta gtggagaagg gcatggccca tatttccaat accaaccagc
     4501 atgacattgg taatagagtt gtcattgagc aaatcggcaa aaaatgtcat tagttttttg
     4561 acatcatagc caaaaccacg acgaccaagt tcaccaaaat aggaaaaatc acgacgtacg
     4621 gtcgctgaat caataccgat agcctctgca atttgcttag agttggcacg ttcaatcttt
     4681 tctgcatgaa atctcttaaa aattcgatag tagagagaga gtctttttgc tgtagctttt
     4741 ggaatagcaa actgtttatc tttcacaaaa tcacaacctt tctattcttc tattttatag
     4801 aaacattgtg aaaaaatcaa caaaaataag aaaaaactaa gaaaaatctt agttttgatg
     4861 taaaaaatct gcatgagata gaaaacggta gaggtctccg accagcccct gataaacttt
     4921 tttgccccta aaagtcagag aagtcacata aagtgtatct ggtaaggtta cacatcctga
     4981 caaagtcaac atgagagcct catgatcctc atacttgaga gtacgctcta catgatagca
     5041 gtccttatag gtcagttcaa acattttggc tctatctttc cgattttgta aagacaccac
     5101 gttctaccaa gctatccatg aggaagtaga atttttcctg atgaatatgg tggtcttctg
     5161 atttgaaaat atcaactaga cgaaggccaa acttgtcagt gatattgatt ttagcccctg
     5221 taagttcctt gttaatgatg attttgagtt ggaagccttc accgctgttt ggcacttttt
     5281 ccaaaaggcg agtcagttca tagttaccaa ccttagtttc aaaaaaggtg ttatctttga
     5341 gggtgaattt tttaacagaa gggctaagag tgtaatcgta acgacaattt tttaactgaa
     5401 tgattttttc aaatgccata tggctaacct ccgataattt cttttaaggt ttttgcgagg
     5461 gtttgtaggt cttcaacggt attttgtggc gacaaactga tgcgaaggga ttccttcaag
     5521 cgttctgaat ttgcgccata catggcttca agaacatggc tggattggac aacgcctgca
     5581 gtacaggctg agccagtaga gattgaaatt ccagctaaat ctagccgaag gagtaagagg
     5641 tcatttttct gaccaggaaa tccaatattg agaacataag ggagatgatg ttttcctcta
     5701 ttcaggtaat actgaatgcc ctccagctct gccagaaagg cagtttctag attttgtaca
     5761 tgttgaaaat gttcttcttg tttttctagg tcttctttta gggctgcaac catgcctaca
     5821 atggcaggca gattttcagt tcctgcacgt tttttctgtt cctggtctcc gccatgtaga
     5881 taggaatcaa agtccatgct agatgcgtag agaaaaccga ttcccttagg accatggaat
     5941 ttgtgggcag aagcagtgag aaaatcaatg cccaattctt ctgaatgaat tgggatttta
     6001 ccaatagcct gaactgcatc aacatgatag gcagcagggt gttgcttgag tatttggcca
     6061 atttcagcga tgggcagtag gtttcctgtc tcattattga caaacatggt agaaaccaaa
     6121 atcgtatcgt cacgtaaagc cttttgaatt tgctgggctg tgatttcttg attttttggc
     6181 tggataatgg ttgcttcaaa cccaaagtgt tgaaccaagt aatcaattgt ttcaaggaca
     6241 gcatggtgct cgatggcagt tgtgatgata tgttttcctt gttcttggtg acgaagacag
     6301 tagccaatga tggtagtatt attgccttca gtcccaccag aagtgaaaaa gatatgttga
     6361 ggttttgtcc ttagtaactg ggctagttcc tgacgggctt ctcgtaagag tttgccagct
     6421 tgacgaccat gaccatgaat actagaagga tttccgtggg tttcttgcat aaccttggtc
     6481 atagctgaaa tagcaactgc tgacatagga gtcgttgcag cattgtccaa ataaatcaaa
     6541 gaatcacctt atttcttttt attgtaggca aagagtgggc tgactggttt tctttcgtga
     6601 atacggacga tagcatcacc aattaactca ctagcagtga tgtagcatac atttttagga
     6661 gttttttctt ttgttgctac tgaatcagtc acaagaattt ctttaatatt agtattgtca
     6721 agaagctcag cagctccctc gacgaagaga ccgtggctag aaacagcata aatttctgta
     6781 gctccttcac gttcaacgat tttagaagct tcagagaagg tacgtcctgt atttaaaata
     6841 tcatcaatca agatagcttt cttaccttca acatcaccaa taatataacc ttcgttacga
     6901 gttgcatcgt cttgagggta gtcgataatg gcgataggag catcaagata ttcagccagg
     6961 ctacgcgcac gtttgacacc tgaattttta gggctaacga caacaacatc tgaaccaagc
     7021 aatcctttat cgcagtaatg ttttgcgaat aggggaacag tgaaaagatt atccactgga
     7081 atatcaaaga aaccttgaac ctgaacggca tgcaaatcaa gagtcaggat acgatcaact
     7141 ccagccttaa ccagcatatt ggcaactagt tttgctgtaa gtggctcacg aggacaagca
     7201 atgcggtctt gacgtgcata gccaaaatat ggaaggacaa cgttgatact gtgggcactt
     7261 gcacgcacac aagcatcgac catgattaac aattccatta ggtggttgtt gacagggaaa
     7321 cttgttgatt ggatgatgta aacatcataa ccacggacac tttcttcgat atttacttgg
     7381 atttctccgt ctgaaaattg acgtgatgat agttttccaa gtgggacacc aacagcttgg
     7441 gcaattttct gtgcaatctc ttggttagag ttgagtgcga aaagtttcat gttttttcta
     7501 tctgacatta tagaccgtcc tctgtaaact ttataaatcc tagttatatt taccttacat
     7561 atatgaactg gggtttgtgt atttttatct tttctatttt accaaaaaat ggagattatt
     7621 tcagctattt ttcatacttt tgacaaatcg aaccaatttt gaaggagctt tttggtagga
     7681 aatctgattt ttctctaaaa attgtcggaa atcctgtttg ccttgctcat gattttccac
     7741 ttcaagctcc aattcgtaat ctgtcatatc aaagtatcgg ctctgatcca gtgccatgag
     7801 accaatagct gttttcattt catagcgaag cgttgttaga caaccaagaa cctgccagtt
     7861 cttactttgg ataccatgtt tcgccaattc atccagtact agcccttgag gaagttcttc
     7921 cttactcaga tagttctcaa catcttttag ttgcaatttt tggttgtatt ccatgtttcc
     7981 aacactctgc gggactttga gtgtcaactc agcccagtct tcaaaggttc gaatgcgcat
     8041 agcgactctc ttttctcgca gttcaaaatc aggcgtgtct atgtagtaat ttgtttgaag
     8101 aacaggagtg acacctgtga actggtcttt tagacgattg tattcatctt ttttcaatag
     8161 tgttttcaat tcaatttcta aatgtttcat ttttcttacc tttttttatc gttgaaagcg
     8221 gatttatggt ataataagca ttgtatttat tgtatatgaa tctggagaaa aaatcaaaga
     8281 tatttttgac ggataatatg agaacaaggg agaatatatg accttagaat gggaagaatt
     8341 tctagatcct tacattcaag ctgttggtga gttaaagatt aaacttcgtg gtattcgtaa
     8401 gcaatatcgt aagcaaaata agcattctcc aattgagttt gtgaccggtc gagtcaagcc
     8461 aattgagagc atcaaagaaa aaatggctcg tcgtggcatt acttatgcga ccttggaaca
     8521 cgatttgcag gatattgctg gcttacgtgt gatggttcag tttgtagatg acgtcaagga
     8581 agtagtggat attttgcaca agcgtcagga tatgcgaatc atacaggagc gagattacat
     8641 tactcataga aaagcatcag gctatcgttc ctatcatgtg gtagtagaat atacggttga
     8701 taccatcaat ggagctaaga ctattttggc agaaattcaa attcgtactt tggccatgaa
     8761 tttctgggca acgatagaac attctctcaa ctacaagtac caaggggatt tcccagatga
     8821 gattaagaag cgactggaaa ttacagctag aatcgcccat cagttggatg aagaaatggg
     8881 tgaaattcgt gatgatatcc aagaagctca ggcacttttt gatcctttga gtagaaaatt
     8941 aaatgacggt gtaggaaaca gtgacgatac agatgaagaa tacaggtaaa cgaattgatc
     9001 tgatagccaa tagaaaaccg cagagtcaaa gggttttgta tgaattgcga gatcgtttga
     9061 agagaaatca gtttatactc aatgatacca atccggatat tgtcatttcc attggcgggg
     9121 atggtatgct cttgtcggcc tttcataagt acgaaaatca gcttgacaag gtccgcttta
     9181 tcggtcttca tactggacat ttgggcttct atacagatta tcgtgatttt gagttggaca
     9241 agctagtgac taatttgcag ctagatactg gggcaagggt ttcttaccct gttttgaatg
     9301 tgaaggtctt tcttgaaaat ggtgaagtta agattttcag agcactcaac gaagccagca
     9361 tccgcaggtc tgatcgaacc atggtggcag atattgtaat aaatggtgtt ccctttgaac
     9421 gttttcgtgg agacgggcta acagtttcga caccgactgg tagtactgcc tataacaagt
     9481 ctcttggcgg tgctgtttta caccctacca ttgaagcttt gcaattaacg gaaattgcca
     9541 gccttaataa tcgtgtttat cgaacactgg gctcttccat tattgtgcct aagaaggata
     9601 agattgaact tattccaaca agaaacgatt atcatactat ttcggttgac aatagcgttt
     9661 attctttccg taatattgag cgtattgagt atcaaatcga ccatcataag attcactttg
     9721 tcgcgactcc tagccatacc agtttctgga accgtgttaa ggatgccttt atcggtgagg
     9781 tggatgaatg aggtttgaat ttatcgcaga tgaacatgtc aaggttaaga cctttttaaa
     9841 aaagcacgag gtttctaagg gattgctggc caagattaag tttcgaggtg gagctattct
     9901 ggtcaataat caaccgcaaa atgcaacgta tctattggac gttggagact acgttaccat
     9961 ttacattccc gctgaggaag gctttgaaac cttggaggct attgagcatc cattagatat
    10021 tctctatgag gatgaccact ttctagtctt gaataaaccc tatggagtgg cttctattcc
    10081 tagtgtcaat cactctaata ccattgccaa ttttatcaag ggttactatg tcaagcaaaa
    10141 ttatgaaaat cagcaggttc acattgttac cagactagat agggacactt ctggcttgat
    10201 gctctttgcc aagcacggtt atgcccatgc acgattagac aagcagttgc agaagaaatc
    10261 tatcgagaaa cgctactttg ctttggttaa gggagatgga catttggagc cagaagggga
    10321 aattattgct ccgattgcgc gtgatgaaga ttccattatt accagacgag tggctaaagg
    10381 cggaaagtat gcccatactt catacaagat tgtagcttct tatggaaata ttcacttggt
    10441 ctatattcac ctgcacactg gtcgaaccca tcaaatccga gtccattttt ctcatatcgg
    10501 ttttcctttg ctgggagatg atttgtatgg tggtagtctg gaagatggta ttcaacgtca
    10561 ggctctgcat tgccattacc tatcctttta tcatccattt ttagagcaag acttgcagtt
    10621 agaaagtccc ttgccggatg atttcagtaa ccttattacc cagttatcaa ctaatactct
    10681 ataaaaactg tctcagagta taattattat cttaaaggag aaaactcatg gaagtttttg
    10741 aaagtctcaa agccaacctt gttggtaaaa atgctcgtat cgttctccct gaaggggaag
    10801 agcctcgtat tcttcaagca acaaaacgct tagtaaaaga aacagaagtg attcctgttt
    10861 tgcttggaaa tcctgaaaaa attaaaattt atcttgaaat tgaaggaatc atggatggtt
    10921 atgaggtcat cgaccctcaa cattatcctc aatttgaaga aatggtttct gccttggtgg
    10981 agcgtcgcaa gggcaaaatg actgaagaag atgtacgcaa ggttttggtt gaagatgtca
    11041 actactttgg tgtgatgttg gtttacttgg gcttggttga tggaatggtg tcaggagcga
    11101 ttcactcaac agcttcaaca gttcgtccag ctctacaaat catcaaaact cgtccaaatg
    11161 taactcgtac ttcaggagcc ttcctcatgg ttcgtggtac ggaacgttac ctatttggag
    11221 actgtgccat taacatcaat ccagatgcag aagccttggc tgaaattgcc atcaactcag
    11281 caatcacagc taagatgttt ggcatcgaac ctaaaattgc catgttgagc tattctacta
    11341 aaggttcagg gtttggtgaa agcgttgata aggtcgttga agcaactaaa attgctcacg
    11401 acttgcgtcc tgaccttgaa atcgatggtg agttgcaatt tgatgcagcc tttgttcctg
    11461 aaactgcagc tctgaaagct cctggaagta cggtagctgg tcaagcaaat gtcttcatct
    11521 tcccaggtat cgaggcagga aatatcggtt acaagatggc tgaacgcctg ggtggctttg
    11581 cggctgtagg acctgttttg caaggtttaa acaagccagt taatgatctt tctcgtggat
    11641 gtaatgcaga tgatgtttac aagttgaccc tcatcacagc agctcaagca gttcatcaat
    11701 agtgaaaact ataaagcgat atactatgct atactgtagt tatgaaacta tgtacgaaaa
    11761 gcactgccat taattcctga gaactaaatt actgattggt gtcaaaaagg aaaacttcca
    11821 agcgatgata tcctgtttat acacgaccta tagaaatctg taatatgtat gtccgtaaaa
    11881 cgataatttc cctttttgat tttaaatgag tatgaaaaga gaatttttca tgagaaaacg
    11941 cataatatta agtgtcttga cacctgctat tatgcgtttt ttataatttt tgcacctttc
    12001 ttagcctttg ttatcgacaa gtattgttct agctccttgt ttttagaatg gcaatttccc
    12061 agcgaaagca cccagttttt tcttagtagt ttcatcgatt tgttcaagag cagagttgat
    12121 ggcttgaacg gtcatatcag aaagagtttc aaggtcctct gggtcaatga cagctggatt
    12181 gaaatcaatg ctgataactt tcttatctcc agttaaggtc gcttggacaa gatcttgagc
    12241 agatttgcca acaaattgca tagcagcaag ttcagcttgg ctttgttcca tttgtttttg
    12301 aagtttttgt gcttgacgca tcatgttttg catgttcatc ataagatttc taaagttcct
    12361 ttcatctcaa ggggataatc cttgttgtta acaagtgcct gattttctct cctaattgtt
    12421 attagtagca tagccatcaa gcccaagtat tgattttatt ataccatttt tttaagacat
    12481 agtcttttat tggtgagagt tatttatgtc aaggagtgat tagaaataaa ttaaaataat
    12541 gatttttgct aagagggctc tattctagtt tcatggaaat gattttacta aaggttcgta
    12601 tgctttgttt gcaaacatgt tacatctatc tatttttgga taaatagttg tctattatta
    12661 tttttatgct aatagtaaaa tctaaatggt agcctacgat tttttagaaa gaaaatggta
    12721 caatatttct aagagaaaat acaatgggag gtaaaatgag gttattacct ataagaaaaa
    12781 tatcacgtca gtctaaaagg ttagcacttt ttttgacgtt ttgtgctgga tatgtggatg
    12841 cttacacttt tattgttcgc gggaataccc ttgtagctgg acaaactgga aatgttgtct
    12901 ttctttcagt agaattaatt aaaaataatg tttcggatgt tagggacaag gttctcacct
    12961 tgctagcgtt tatgatggga gtctttttat taacgattta taaggaaaaa ttgagaattg
    13021 tgaaaaaacc tattctgtcc ttgattccct tggcaatctt atcaatcatt attgcttttg
    13081 tgccgcaaac tgtggataat atctatctag tgccgccctt ggccttctgt atgggactgg
    13141 tgacaactgc ttttggagaa gtgtcgggta ttgcctataa taacgctttt atgacaggga
    13201 atatcaaacg gaccatgctg gcttttggag attatttccg aaccaagcac actccttttt
    13261 tgcgtgaagg attcatattt gttagcctgc ttagtagttt tgtccttggc gttgtctttt
    13321 cagcctattt gacgattttc tatcatgaaa agaccattct tggtgttcct attatgatga
    13381 gcgtttttta cctcagcatg ctttttgcct cttggcagaa aaaagtaaaa gaaaaagctt
    13441 cattttaggt gttattactt gtaagaaaat aggagatatg ctatacttga agagttgact
    13501 atgcacgatc ctgtgcaacc gcacgaacat cgttgcttga ttattcaagt ttaagtggtt
    13561 cgtcccacga tgctaggcga gtcttcacaa aaaatcgggg aaacccataa aaatcatagg
    13621 aggtgcataa tgagcacata cgcaattatc aaaactggcg gaaaacaagt taaagttgaa
    13681 gttggtcaag cagtttacgt tgaaaaattg aacgttgaag ctggtcaaga agttactttt
    13741 aacgaagttg ttcttgttgg tggtgaaaac actgttgtcg gaactccact tgttgctgga
    13801 gctactgtag ttggaactgt tgaaaaacaa ggaaaacaaa agaaagtggt tacttacaag
    13861 tacaaaccta aaaaaggtag ccaccgtaaa caaggtcacc gtcaaccata tacaaaagtt
    13921 gtcatcaacg caatcaacgc ttaattttaa ggagaacaca tgatacaggc agtctttgag
    13981 agagccgaag atggcgagct gaggagtgcg gaaattactg gacacgccga gagtggcgaa
    14041 tacggcttag atgtcgtgtg tgcatcggtt tctacgcttg ccattaactt tatcaattct
    14101 attgagaaat ttgcaggcta tgaaccaatc ctagaattaa acgaagatga aggtggctat
    14161 ctgatggttg aaataccaaa agatcttcct tcacaccaga gagaaatgac ccagttattc
    14221 tttgaatcat ttttcttagg tatggcaaac ttatcggaga actcttctga gttcgtccaa
    14281 accagagtta tcacagaaaa ctaacacgga ggaaaacatt atgttaaaaa tgactcttaa
    14341 caacttgcaa cttttcgccc acaaaaaagg tggaggttct acatcaaacg gacgtgattc
    14401 acaagcgaaa cgtcttggag ctaaagcagc tgacggacaa actgtaacag gtggatcaat
    14461 cctttaccgt caacgtggta cacacatcta tccaggtgta aacgttggtc gtggtggaga
    14521 cgatactttg ttcgctaaag ttgaaggcgt agtacgcttt gaacgtaaag gacgcgataa
    14581 aaaacaagtt tctgtttacc caatcgctaa ataaaaaggt ccattgaacc ttttatcccg
    14641 aaccttgaaa tataaaggtg aggaagctag aaacagctta aaataag
//
LOCUS       DAVHKZ010000045        14474 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000045 DAVHKZ010000000
VERSION     DAVHKZ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.045"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            83..880
                     /locus_tag="VVO74_001840"
     CDS             83..880
                     /locus_tag="VVO74_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU5695826.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..2287
                     /locus_tag="VVO74_001841"
                     /pseudo
     CDS             1028..2287
                     /locus_tag="VVO74_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2383..3657
                     /locus_tag="VVO74_001842"
     CDS             2383..3657
                     /locus_tag="VVO74_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU5695827.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VVO74_001843"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VVO74_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU5695828.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="VVO74_001844"
     CDS             4786..5088
                     /locus_tag="VVO74_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU5695829.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKHQS
                     VMADLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="VVO74_001845"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="VVO74_001845"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU5695830.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /locus_tag="VVO74_001846"
     CDS             5962..7302
                     /locus_tag="VVO74_001846"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU5695831.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="VVO74_001847"
     CDS             7280..7492
                     /locus_tag="VVO74_001847"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU5695832.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="VVO74_001848"
     CDS             7489..8364
                     /locus_tag="VVO74_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU5695833.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQVPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="VVO74_001849"
     CDS             8357..9172
                     /locus_tag="VVO74_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU5695834.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKVPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="VVO74_001850"
     CDS             9165..9596
                     /locus_tag="VVO74_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU5695835.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="VVO74_001851"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="VVO74_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU5695836.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDMTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="VVO74_001852"
     CDS             11272..12000
                     /locus_tag="VVO74_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU5695837.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="VVO74_001853"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="VVO74_001853"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU5695838.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14106..14186)
                     /locus_tag="VVO74_001854"
                     /pseudo
     CDS             complement(14106..14186)
                     /locus_tag="VVO74_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            14359..>14474
                     /locus_tag="VVO74_001855"
     CDS             14359..>14474
                     /locus_tag="VVO74_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIC"
                     /protein_id="HEU5695839.1"
                     /translation="MVLDYFFDKNLVLCLEADNQEQLFDQVASLLEEREIVTP"
BASE COUNT         4303 a         2623 c         3422 g         4126 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg atacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat gatatggagg
     1021 tcaccttatg acttgtgatt ttaaatctga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aaacttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaata ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggatggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagtagcc tttattatag ctgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa accctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttattat gccttggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggtcatt gatcatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caatcactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatc aaatccactt
     2221 gtctatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccttca
     2341 tgcatgatat aatggttaca gaagtctaga aagaggaacg atatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gagagtcagt atgccgaact cttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaagcagga actggccttg
     2521 gcggagcaaa aggccatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattac agagtcagat ccaaaacttt gatacagaaa aagaattggc caagaaagag
     2641 gttgaacaga caagccatga ggctctcttg gctaaggaca aggaagtaca gctcttagaa
     2701 aatcagttgg ctaccttgcg tttggagcat gaaaatcaac tacaaaagac cctttctgac
     2761 ctagaaaaag aacgggatca ggttaaaaac caactacttt tgcaggaaaa ggaaaatgaa
     2821 ttatctttgg cttctgttaa gcaaaactac gaagcccagc tcaaggcagc tagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcagac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatgcta gtggggaagt gatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc ggacaagtcc gatttcttat
     4141 gatggccaac ttgctcgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgat aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctggt gggaacttag gcccaggatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaaca ccaatcggtc
     4921 atggccgatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggagcctcaa gatgtcttta
     5521 tcgttgaggg cattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgta ttattcgtcg tatcaagcgt gatatggagg
     5641 aacgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat aaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaaatat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtctatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctaccccaa
     6361 ttttctaaga gaattggggt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatcctac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgagacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattaactca tttgcaaaat
     6781 caggaaaaac ggatggcaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagat caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttgcca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttggagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagatcaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gtaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattggaag aaattgccca gcaggttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaagttcca gatgataccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta agattcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggca ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaaa
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattaccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgatacttt tgcagacaag atttttagtt gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgcctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ctatgaatga catggaaagt gtcgaagagt
    10381 atgatcctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctga
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgctaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cgttttagta
    10801 agggaaaatt cagtcgtgag ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagtatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattttt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatatgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tctcaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgca atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcggcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatctttgt tcacgcaggt
    11701 attgatttga ccttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacagga gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccac ggaaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggat
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatggag aaacttatat tttccacttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagcg cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 gggattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aagtacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggttttc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga cctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaattgt ctttgacttc tttgataaac ttaagtcttc aacacgtggt
    13501 tatgcaagct ttgactacga attgtcagaa tatcgcccat ctaagctggt gaaaatggat
    13561 atccttctca atggagataa ggtggatgct ctcagcttta tcgttcacaa ggactttgcc
    13621 tacgaacgtg ggaaactcat cgttgataaa ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaagttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcatcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaacctcaa aaccatgttt tgagctgact
    14101 tcgtcagtct tatctacaac ctcaaaactg tgttttgagt aacctgcggc tagcttccta
    14161 gtttgctctt tgattttcat tgagtattag aacagaaaaa tgcttggagt atttgtttgt
    14221 gtgtttattt ttatataaca aactataaac aaaacaaaaa tataaaaaag agacaaaaaa
    14281 gaacagaaag taattaacaa cgatttcata tagtgttata cttatggcat aaagttaatg
    14341 gaaagaaggg aaaaccttat ggtattagat tatttctttg acaaaaacct tgtgctttgc
    14401 ttagaagcgg ataatcaaga acaactcttt gatcaggtag caagcttgtt ggaagaacga
    14461 gaaattgtca ctcc
//
LOCUS       DAVHKZ010000046        14322 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000046 DAVHKZ010000000
VERSION     DAVHKZ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14322
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.046"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(85..648)
                     /locus_tag="VVO74_001856"
     CDS             complement(85..648)
                     /locus_tag="VVO74_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU5695840.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(632..1183)
                     /gene="coaC"
                     /locus_tag="VVO74_001857"
     CDS             complement(632..1183)
                     /gene="coaC"
                     /locus_tag="VVO74_001857"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU5695841.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETLDEKTL"
     gene            complement(1195..1884)
                     /gene="coaB"
                     /locus_tag="VVO74_001858"
     CDS             complement(1195..1884)
                     /gene="coaB"
                     /locus_tag="VVO74_001858"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU5695842.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLFAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            2114..3784
                     /locus_tag="VVO74_001859"
     CDS             2114..3784
                     /locus_tag="VVO74_001859"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU5695843.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            4112..5287
                     /gene="mutY"
                     /locus_tag="VVO74_001860"
     CDS             4112..5287
                     /gene="mutY"
                     /locus_tag="VVO74_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU5695844.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            5342..6046
                     /locus_tag="VVO74_001861"
     CDS             5342..6046
                     /locus_tag="VVO74_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5695845.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            6039..7388
                     /gene="vicK"
                     /locus_tag="VVO74_001862"
     CDS             6039..7388
                     /gene="vicK"
                     /locus_tag="VVO74_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU5695846.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            7390..8199
                     /locus_tag="VVO74_001863"
     CDS             7390..8199
                     /locus_tag="VVO74_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU5695847.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            8290..8532
                     /locus_tag="VVO74_001864"
     CDS             8290..8532
                     /locus_tag="VVO74_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU5695848.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            8534..8788
                     /locus_tag="VVO74_001865"
     CDS             8534..8788
                     /locus_tag="VVO74_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU5695849.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            8835..9530
                     /locus_tag="VVO74_001866"
     CDS             8835..9530
                     /locus_tag="VVO74_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HEU5695850.1"
                     /translation="MKKKWLFADYYDTTIILLALISVILVLLGFAEMTDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSS"
     gene            complement(9879..10865)
                     /locus_tag="VVO74_001867"
     CDS             complement(9879..10865)
                     /locus_tag="VVO74_001867"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU5695851.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            11059..13527
                     /gene="gyrA"
                     /locus_tag="VVO74_001868"
     CDS             11059..13527
                     /gene="gyrA"
                     /locus_tag="VVO74_001868"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU5695852.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            13527..14270
                     /gene="srtA"
                     /locus_tag="VVO74_001869"
     CDS             13527..14270
                     /gene="srtA"
                     /locus_tag="VVO74_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU5695853.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         4384 a         2483 c         3190 g         4265 t
ORIGIN      
        1 cgttttacta tagtaaagat ttcattaaaa agaaactgta tagagcaaaa tctccacctt
       61 caggtttgaa agcggagatt gtttttattt tttcaaggtt tgtagtcgtg gaacaatggc
      121 tagggttaga attgcagaaa tgaccaattc agcaattgaa tttgttgaga taacggttgc
      181 cagaagaagt tggatatttc cattataaac atttccaaat aggaagaaga ttcctccaag
      241 gacaaagata gtatttgtca aggaaccaag ggctccagct aaaatcagac cagtcttgtt
      301 tttcatcagt ttatagacta agtaaggagt taaaccaatc aaaatacgtg ggacgatggc
      361 aatgatagct gagtagatgt ttccgtttgg tacgaaggga gagaagaggt agcttgtcgg
      421 tagaatcgta atcgtgttaa ccgtcaagct aagtagcccc atcaaaaatc caagtgtaac
      481 cccaactcgt ggaccataaa taatgctggc aataatgaca ggaatatgaa caatggtcgg
      541 tttgattgga aatggaaaaa ggttaaagat aagtgagctc agaaagtgta tcacgagcat
      601 ggtagcaaaa aagatagcaa tgggtgcaat attagagcgt tttttcatcg agagtttcct
      661 ttattctttc taaaataatt gtgaggtcag ctaaagctcc tcgtccgtgg tctccacaag
      721 ctagtaggga ttccttagga gcaatcagct gatagccgta ggtttctaat gttttcagat
      781 tattctgagt tactggatgg tcatacattt ttgtattcat agcaggagct attagtttgg
      841 gaatatgact tggcagggct agagctgtac tggttaccat gttgtccgca aatccgtgag
      901 ctagttttgc aatagtgtta gcagttgcag gtaccacgat aaataaatct gctttttttc
      961 caagttcgat atgattgacc tgatcaggat agggttcctt catgacatcc aagtggacag
     1021 gattctgtga gagtacctgt agtgtcaaag gttggataaa ctctgtagca gcctgagtca
     1081 ttaagacagt gacttgatgg ccttgttttt ttagagaact gactaaatct gccgacttat
     1141 aagaggcgat tgaacccgtt acagccaaga gaatgtttgc catagttttc ctttctaaga
     1201 atgataggct tgaatttttt caaggaggag ttctgcaatt tcttctttag tctggactgt
     1261 ttgaagctga tttttctcaa caaatatagc tcggtgctga cctgctgaaa tttgagtcag
     1321 gtcattcgcg atgattaaat ctgcttgatt cttgataaga ctttttcgtg caatgtcaac
     1381 cagatgatct tcggtaacat caaccagcag tttgaaacca atcagatgaa tagtaggatt
     1441 ccattccttg actagggata tgattttggg tgtcttttta aggaacaaaa cctgaacctc
     1501 atcagttgaa gaaatcttgg cctgatgatt ctgcttgctt aaaaattctt ttagattgga
     1561 gctagcctga acttcctcaa gccctgtcat ataaacagga gtgtagtcag aaacagccat
     1621 tgagtggatc aagacctgat aatcctgaac acgttcttgc atttctatta gaaggtcctt
     1681 ggtattggta atttctcgaa tacttaggtt aggatgaggc tctggcttca gagctcgttt
     1741 tgtcgtaatt aaacaaactt catgccctgc aaaaagcaaa gtctctgtga taattttccc
     1801 caagtgacct gtagaatggt tagtgataga gcggacgcta tcgatagctt cactggtacc
     1861 gcccgatgta actaaaattt tcatagcact attgtacaca aaaataagcg gtaagtaaaa
     1921 tgaaagtgat aaatttttgg taaaaacgaa gatttactat agtttcaaac tataaaacca
     1981 tataaaattt aagaaaggac tctaaaagcc ttaaaaacag agatatttac gaacgtttag
     2041 agagttttag gatgttaaaa atcttgtttt gtgatataat gaattatcat ataagaggtt
     2101 agaggaattt tgaatgaaaa cagatattga aatcgcacag agtattgagt tgaagccaat
     2161 tgttgatgtt gtagagaaac ttggtatttc ttatgacgat ttggagttgt acggaaagta
     2221 caaggctaaa ctcagctttg ataaaattcg tgcagttgag agcaatccag tcggtaaatt
     2281 gatcttggtt actgccatca acccaacacc tgcaggtgaa ggaaagtcga cacttaccat
     2341 tggtcttgcg gatgccttga acaagattgg caagaaaacc atgattgcta tccgcgaacc
     2401 gtctcttggt ccagtcatgg ggatcaaggg tggtgctgct ggtggtgggt atgcacaagt
     2461 tctgccaatg gaagacatca acctccactt tactggagat atgcatgcta ttacaactgc
     2521 caacaatgcc ctttctgcct tgattgacaa ccacttgcac caagggaatg agctggaaat
     2581 tgatcaacgt cgtatcctct ggaaacgcgt tgtggacttg aacgaccgtg cgctccgcca
     2641 tgtgactgtt ggtcttggtg gtcctctaaa cggtattcca cgtgaggatg gttttgatat
     2701 tacagttgct tcagaaatca tggcaattct ttgcttggca acggacatcg aggacttgaa
     2761 acgtcgtttg gcgaatatcg ttattggtta tcgctatgac cgtacgcctg tttctgtagg
     2821 tgatttgcag gttgagggtg ccttggcttt gattttgaag gatgctatta agccaaactt
     2881 ggttcagaca atttacggta cacctgcctt tgtacacggt ggtccatttg ccaatatcgc
     2941 tcatggctgt aactctgttt tggcgacgac aacagccctt cacttggctg attacactgt
     3001 tactgaagct ggttttggtg cggaccttgg tgctgagaaa ttccttgata tcaagacacc
     3061 aaacttgcca acatctccag atgcagttgt tattgtcgca acccttcgtg cccttaagat
     3121 gaatggtggt gtggctaaag acgctctgac tgaagaaaat gtagaggcag ttcgtgcagg
     3181 ttttgctaac ttgaaacgcc acgttgaaaa tatccgtaag ttcggtattc cagcagttgt
     3241 agctattaac gaatttgtat ctgatacaga agctgaaatt gcagccttaa aagaactctg
     3301 tgcctcaatc gatgtaccag ttgaattggc tagtgtctgg gctgatggag cagaaggtgg
     3361 agtagcactt gccgaaacag ttgttaagac aattgctgaa aatccagcta actataaacg
     3421 tttgtacgat aatgaccttt ctgtccaaga aaagattgaa aaaattgtca ctgaaatcta
     3481 tcgtggtagc aaagtgaact ttgagaagaa agctcaaaca caaattgctc aaatcgttca
     3541 aaacggttgg gacaaattgc caatctgtat ggctaaaact caatacagtt tctcagacaa
     3601 tccaaatgcg cttggagcac cagaaaactt tgaaattacc attcgtgaat tggtaccaaa
     3661 attaggtgca ggcttcatcg ttgccttaac tggtgatgtt atgaccatgc caggtcttcc
     3721 aaaacgtcca gcagctctca acatggatgt tgaaagcgat ggaactgtac taggcttgtt
     3781 ctagtggatt gaaattgact ttaagtgagt ttggaaataa tatccaagct cattttttct
     3841 cagactgcaa gcagttcatc aataagattt atactcttcg aaaatctctt caaactacgt
     3901 cagcttcacc ttgccgtagg tatatgatac tgactctgtc agttctatcc acaacctcaa
     3961 aacagtgttt tgagcaacct gcggctagct tcctagtttg ctctttgatt ttcattgagt
     4021 ataagtagat agaaaagtta tatactatct attgaaaata ttataaatca gatacaaaga
     4081 caggtgaaac cttctgtgtt atactagaga tatgttagat ttgaaagaat acggtatcgt
     4141 catgtggccg gaggagaaag tcatttcttt ccgtgagaaa cttctcgctt ggtatgatga
     4201 aaacaaaaga gatttgcctt ggaggagaag taaaaatcct tatcacatct gggtatctga
     4261 aatcatgctt cagcagacca gggtggatac agttatccct tactacgaaa gattcctgga
     4321 ctggtttcca actgtcgaaa gtctggcaac tgcgcctgag gagagtttac tgaaagcttg
     4381 ggagggcttg ggctattatt ctcgagttcg caatatgcag gctgcagccc agcagattat
     4441 gactgacttt ggtggccaat ttccaaatac ctatgaagga atttccagct tgaaagggat
     4501 tggaccttac acagcaggag ccatttccag tattgctttt aacttgcctg agccagctgt
     4561 agatggtaat gtcatgcggg tcttggcgcg tctgtttgaa gtcaaccacg atattgggat
     4621 tccaagtaat cgaaaaattt ttcaggcaat gatggagatc ttgattaatc cggatcgtcc
     4681 gggtgatttt aatcaagcct tgatggactt agggtctgat attgagtctc ctgtaaatcc
     4741 cagacctgaa gaaagcccag tcaaggactt tagtgcggca tatcagaatg gaaccatgga
     4801 ccgttatcca attaaatctc ctaagaaaaa gccggttcct atttatctta aagccttagt
     4861 tgtgaaaaat tctcaaggac aatttttact tgaaaaaaat gaaagcgaaa agctcttggc
     4921 aggtttttgg catttcccct ttatagaagt tgataacttt tcgcaagaag agcagtttga
     4981 cctctttcat caggttgcgg aagaaagtgt gaactttggc cccagtccag aagagagttt
     5041 ccagcaggac tatgacctag atgttgattg gcttgatgtt tgttttgata cagtccagca
     5101 tgtttttagt catcgaaaat ggcatgtaca gattgtagca ggtcaggtga gtgacttcca
     5161 tgatttttca gatagggaag ttcgttggct ttcaccagaa gaattcaaga attacccact
     5221 tgccaaaccc caacaaaaaa tctggcaggc ttatgcacaa gccaacttag acagtagcca
     5281 agactagcta ttgtgtcttc tgactatttt ttggtataat agtagagaaa aaggtgaaca
     5341 tatgaaaaaa atactaattg tagatgatga gaaaccaatc tcggatatta tcaagtttaa
     5401 tatgaccaag gaaggttacg aagttgtaac tgcttttaat ggtcgtgaag cgctagagca
     5461 atttgaagca gagcaaccag atattattat tctggatttg atgcttccag aaattgatgg
     5521 tttagaagtt gctaagacca ttcgtaagac aagcagtgtg cccattctta tgctttcagc
     5581 caaagatagt gaatttgata aggttatcgg tttggaactt ggggcagatg actatgtaac
     5641 gaaacccttc tccaatcgtg agttgcaggc gcgtgttaaa gctcttctgc gtcgttctca
     5701 acctatgcca gtagatggtc aggaagcaga tagtaaacct caacctatcc aaattgggga
     5761 tttagaaatt gttccagacg cctacgtggc taaaaaatat ggcgaagaac tagacttaac
     5821 ccatcgtgaa tttgagcttt tgtatcattt agcatcgcat acaggtcaag tcatcacgcg
     5881 cgaacacttg cttgagactg tctggggtta tgactatttt ggtgatgtcc gtacagttga
     5941 tgtgactgta cgacgtctgc gtgagaagat tgaagatacg cccagccgac cagagtatat
     6001 cttgacgcgc cgtggagtag ggtattacat gagaaataat gcttgattta ctgaaacaaa
     6061 ccatttttac cagagatttt atctttatcc tgattttgtt aggtttcatc cttgttgtga
     6121 ccctcttatt actggaaaat agacgtgata atattcagtt gaagcaaatc aatcaaaagg
     6181 ttaaagattt gattgcagga gattattcca aggttcttga tatgcaaggt gggtctgaaa
     6241 tcaccaatat taccaataat ttgaatgact tgtcggaggt tattcgtctc actcaggaaa
     6301 atctagaaca agagagtaag aggctaaata gtattctgtt ttatatgaca gatggggttc
     6361 ttgcgaccaa ccgtcggggt cagattatca tgattaacga tacagccaag aagcaactgg
     6421 ggttggttaa ggaagatgtt ctgaatagaa gcattttgga attgctcaag atagaagaaa
     6481 actatgaatt gcgtgatttg attacccaaa gtccagaatt gttgctagat tcccaagata
     6541 tcaatggcga atatttgaac cttcgagttc gctttgcctt gatacgtcga gagtctggct
     6601 ttatttcagg tttggtggct gttttgcatg atacgacgga gcaggagaag gaagaacgcg
     6661 aacgaagact ctttgtttcc aatgttagcc atgagttacg gactcctctg actagcgtaa
     6721 aatcctatct tgaagccttg gatgaggggg ctttgtgtga aactgtagca ccagacttta
     6781 tcaaggtttc tcttgatgag accaaccgta tgatgcgcat ggtgacggat ctcctccatc
     6841 tttcacgtat tgataatgct accagtcacc tagatgtgga actgattaac ttcactgctt
     6901 ttattacctt tatcctcaat cgttttgaca agatgaaagg acaggaaaag gagaaaaaat
     6961 atgagttggt gagagattat cccatcaatt ctatctggat ggaaattgat acagataaga
     7021 tgacgcaggt tgtcgacaat attttaaata atgctattaa gtattcgcca gatgggggta
     7081 aaatcactgt cagaatgaag acaactgaag accagatgat tttatccatt tctgaccacg
     7141 gtttggggat tcctaagcag gatttaccac gtatctttga ccgtttctat cgtgtggatc
     7201 gtgctagaag tcgtgcgcaa ggtggtacag gtctaggact gtctatcgct aaagaaatta
     7261 tcaaacaaca taagggcttt atttgggcca agagtgaata cggcaagggt tcaaccttta
     7321 ccattgtgct cccttatgat aaggatgcag tgaaagaaga agtatgggag gatgaagtag
     7381 aagactagaa tgagtgaaat aggctttaaa tacagtattt tagcgtcggg ttccagtgga
     7441 aattcttttt atctggaaac ctcaaaaaag aagcttttag tagatgcagg cttgtctggc
     7501 aagaaaatta ccagtctgct agctgaaatt aaccgtaagc cagaagacct ggatgccatc
     7561 ttgattaccc atgagcattc agatcatatc catggagtag gcgttttggc tcgcaagtat
     7621 ggtatggatc tttatgccaa tgaaaagacc tggcaagcta tggaaaatag taaatatctt
     7681 ggcaaggtgg attcttcgca aaagcatatt tttgaaatgg gtaaaaccaa aacctttgga
     7741 gatatcgaca tcgagagttt tggtgtaagc catgatgcag tcgcaccgca gttctatcgc
     7801 tttatgaagg atgataagag ttttgtcctt ttgacagata caggttatgt cagtgaccgt
     7861 atggcgggca ttgtcgaaaa tgcggatggc tatcttatcg aggccaacca tgatgtagag
     7921 attttgcgat caggttctta cgcttggcga ctcaaacaac gaatcctatc tgaccttggt
     7981 cacctttcta acgaggacgg tgctgaagct atgattcgga cgctaggaaa tcgtactaag
     8041 aagatttacc ttgggcattt atctaaggaa aataatatca aggaactggc tcatatgacc
     8101 atggtcaatc agctggctca agctgatctg ggagtcggag tagactttaa ggtttatgat
     8161 acctcaccag ataccgcaac accattgaca gagatataga aagaacgctg agaaggtgtt
     8221 ctttttatat tgactgaaca cctaaaaagt aatacaatgg tgttaccatt aaaaaaggga
     8281 gcacaaaaga tgactactat tacattaaaa gtttctgaag ctgataaaac atttatgaaa
     8341 gcaatggcta agtttgaagg agtttccctt tcggaactta ttcgcaccaa aactcttgaa
     8401 gccctagaag atgaatacga tgctcgtgtg gcagatttag cctatcaaga gtatttagaa
     8461 gacttggaaa aaggagttga acccattact tgggaagaaa tgatgcatga tttaggcttg
     8521 aaggatgaat aatttgtata aattagttcc aacaagacgt tttatcaagc aattgaaaaa
     8581 attggaccgt tatacgcaga agctaattac aaactattta caaaccaatg ttttggaagg
     8641 tccaagacga cacggaaagg ctttggttgg taatcgcgtt ggtcaatggc gctatagaat
     8701 tggtaattat cgagttatcg tacaaattgt agatgatgaa ttagtcgttg ctactctaga
     8761 agttggtcat cggagagata tttattgaat taaagctgag taataacaat atagaaagta
     8821 aggagagtaa aaatttgaag aaaaaatggt tatttgcaga ttattatgat acaacaatta
     8881 ttttacttgc tttaatctct gttattctgg tattacttgg atttgctgag atgactgatt
     8941 tggacaatcc gccttatagt attattgatt tagtaatctg gggtgttttt gtaattgatt
     9001 atagttggcg cttttttatt actaaaagaa aatggcgctt tattcttgaa aatatttttg
     9061 atttattgac cattctccct ttaaatgcta tttttacagt gtttcgatta ggacgtatct
     9121 tccgcttagc aaggctgaca aaattactga aactgactcg tttacttaga ataattggac
     9181 ttacaggtaa actagaaaga aaaattagta gattcttacg aacaaatgga ttgatttata
     9241 tcttgtatgt taatatcttt attgttctag tagggagttc gattttatcc gttgttgaag
     9301 aaaaatcctt ctcagatagt ctttggtggg ctcttgtgac agtaactact gttggttatg
     9361 gtgatattgt tccagtttcc ctttttggga aatggctagc agttttactg atgcttgtcg
     9421 gtattggaac aatagggatg ctaacaagtg ctttgacgaa cttttttgta aaggataatc
     9481 cagatgaaca gataaaactt gataaactca aagacgaatt atcgagctaa agaatattaa
     9541 tagagaaaca atctgaaaaa atcgaagaac tacattgaat gataaaagac ttagttgaaa
     9601 aaatatcata aaggtgagac aaaataaaac ttgattcgag gagaaatcaa gtaagttttg
     9661 acacaataga acgcatatta tcaggtataa aaacttgata ctatgcgttt tatagagaaa
     9721 taaaataaaa tctgaacaaa tcaattagga atttaaagca ttttataaca acgttttaga
     9781 gtaatggggt gctatttcaa cttcaaccta ctataataca gaaaaaaata cagaaaaaaa
     9841 caactccctg atgattcaag gagttgtcta tagttaaatt agtttttaga agcttcttgg
     9901 aattctggat ttttccatgc ttcgtcaata atagcttgca attctttagc agatgcttgc
     9961 attttttgag tttctgcatc gttcaatgga atgtttactg gacgaacgat accatgtgca
    10021 ccaacaacag ctggttgacc gataaagaca ttctcaactc cgtattgacc ttcttggaat
    10081 actgaaagtg gaagtactgc gttttcatcg tcaaggattg ctttagtgat acgagcaagg
    10141 gctactgcga taccgtagta tgttgcacct tttttgttga tgattgtgta ggctgcatca
    10201 cgaacacctt cgaacaattc aatcaattca gcttcttgaa cattttgagt gtctttaagg
    10261 aattcttcaa gatttacacc agcgatgtta gcgtgtgacc aaacagcgaa ctcagagtca
    10321 ccgtgttcac ccatgatgta ggcgtgcact gaacgagcat ccacatccaa tttttcagca
    10381 agtgcttgac ggaaacgagc tgagtcaagt gaagtacctg aaccgataac gcgttcttta
    10441 gggaaaccag agaatttcca agttgagtaa gtcaaaacgt caactgggtt agcagcaaca
    10501 aggaagatac ctttgaaacc agattcaaca acttgagtta cgattgattt gttgatagca
    10561 aggtttttac ctacaaggtc aagacgagtt tcacctggtt tttgaggtgc acctgcagtg
    10621 atcacaacaa ggtcagcgtc tgcacagtca gagtattgag ctgcatagat ttttttaggt
    10681 gaagtgaagg caagggcgtg actaaggtca agcgcatcac caacagcttt ttcatgcaat
    10741 tgtggaattt cgataattcc aagctcttgt gcaattcctt ggttaacaag tgcaaaagcg
    10801 taagatgaac ctacagcacc atcaccgaca aggataactt ttttgtgttg tttagttgaa
    10861 gtcattgttt taaacatctc cttaatttta ttaggggatt ttccctagac aacttcattc
    10921 tatcactttt aaaaaacttt gtcacgaata tgccttatag ttctcgatgt aaacgtttta
    10981 gtggtttaga ggctgaaata gatgggaatt tatggtataa tgttgttact tactaattgt
    11041 gaaatgaggc atttattaat gcaggataaa aatttagtga atgtcaatct gacaaaggag
    11101 atgaaggcaa gttttatcga ctacgccatg agtgttatcg tagcgcgagc tcttcctgat
    11161 gttcgagatg gcttaaaacc tgttcaccgt cgcattctct acggaatgaa tgaattgggt
    11221 gtgaccccag acaaacccca taaaaaatct gctcgtatta caggggatgt catgggtaaa
    11281 tatcacccac acggggattc ctctatttat gaagccatgg tccgtatggc tcaatggtgg
    11341 agctaccgtt acatgcttgt agatggtcat gggaattttg gttccatgga tggagatagt
    11401 gctgccgctc aacgttatac cgaggcacgt atgagcaaga ttgctctgga aatgcttcgt
    11461 gatatcaaca aaaatacagt tgatttcgtt gataactatg atgccaatga acgggaaccc
    11521 ttggtcttgc cagcgcgttt tccaaacctt ttggttaatg gagcaactgg tatcgcggtt
    11581 gggatggcaa ccaatattcc acctcataat ctgggtgaaa ccattgatgc agtgaagttg
    11641 gtcatggata atcctgaagt gactaccaag gacttgatgg aagtcttgcc tggaccagat
    11701 tttccaactg gtgctcttgt catggggaaa tcaggtatcc ataaggctta tgaaacaggt
    11761 aaaggttcga ttgtcctacg ttctcgtaca gagattgaaa cgactaagac tggtcgtgag
    11821 cgtatcgttg taacagaatt tccttacatg gtcaataaaa ccaaggtgca tgagcatatt
    11881 gttcgcttgg ttcaggaaaa acgcattgag ggtatcacag cagtacgtga tgagtcaaac
    11941 cgtgaaggtg ttcgatttgt tattgaagtc aagcgcgacg cctcagccaa tgttattctc
    12001 aataacctct tcaaaatgac ccaaatgcaa accaattttg gattcaatat gctcgctatc
    12061 caaaatggta taccgaaaat tttgtctctt cgtcagattt tggatgctta tattgagcac
    12121 caaaaagaag tggttgttcg tcgtacacgt tttgataagg aaaaagcgga agcgcgcgct
    12181 catatcttag aaggtctctt gattgcgcta gaccatatcg acgaagtgat tcgtatcatc
    12241 cgtgctagtg aaacggatgc ggaagctcaa gctgagttga tgagcaagtt taagctttct
    12301 gaacgtcaaa gtcaagctat ccttgatatg cgtcttcgtc gtttgacagg tttggaacgc
    12361 gataagattc aatctgagta tgatgacctc ttggctctga ttgcggattt agcagatatt
    12421 cttgctaagc ctgaacgtgt ttctcaaatt atcaaagacg aattggatga agttaaacgt
    12481 aaattttctg ataaacgccg tacagagttg atggttggac agatcttgag tctcgaggat
    12541 gaggacttga ttgaagaatc ggatgtcttg attacccttt ctaacagagg ctacattaag
    12601 cgtttggatc aggacgagtt cactgctcaa aaacgtgggg gtcgtggtgt ccaaggaacg
    12661 ggagtgaaag atgatgactt tgttcgtgag ttagtgtcaa ctagcaccca tgatcatctg
    12721 ctcttcttca caaacaaggg acgtgtctat cgtcttaaag gttatgaaat tcctgagtat
    12781 ggtcggactg ccaaagggct accagtagtc aatctcttga aattggatga agatgaaagt
    12841 attcagacgg ttatcaatgt tgagtctgat cgcagtgatg atgcttatct cttctttaca
    12901 acccgtcacg gtattgtgaa gagaactagt gttaaggagt ttgccaatat tcgtcaaaat
    12961 ggtctcaaag cgctgaattt aaaggatgaa gatgagttaa tcaatgtctt gttgacagaa
    13021 ggagatatgg atattatcat tggtaccaag tttggttatg cagttcgctt taatcaatca
    13081 gccgttcgtg gtatgagccg tatcgccact ggtgtgaaag gtgttaacct tcgtgaagga
    13141 gacacagttg ttggtgccag cttgattact gatcaagatg aggttcttat tatcacagaa
    13201 aaaggatatg gtaagcgtac agtcgctact gaatacccaa caaaaggtcg tggtggtaag
    13261 ggaatgcaga cagctaaaat taccgaaaaa aatggcttgc tggccggtct tatgactgtt
    13321 caaggggatg aggatttgat gattatcact gatacaggtg tcatgattcg aaccaatctt
    13381 gccaatattt cacaaacagg acgtgcaact atgggagtta aagtaatgcg cctggatcaa
    13441 gatgctcaga tagtgacttt cacaacggtt gcggtggcag aaaaagaaga agttgggaca
    13501 gaaaacgaaa cagaaggtga agcataatgt ctcaaaaaaa taataaaaag aaaaacaagc
    13561 gaaaaaatct gctgacaaat atcctagcag gatttctgat attactgtca ctggctttga
    13621 tttttaatac tcaaattcga aatattttca tagtctggaa taccaataag tatcaagtta
    13681 gccaggtatc aaaagaaaaa ttagaagaaa atcaggatac agaaggcaat tttgactttg
    13741 attctgtcaa agctatctct tcggaagctg ttctaacttc tcaatgggat gctcaaaaat
    13801 taccagttat tgggggaatt gcaattcctg aattggaaat gaatttgccg atttttaaag
    13861 gacttgataa tgttaatctc ttctacggag ctggtacaat gaaacgcgag caagtaatgg
    13921 gagaaggaaa ttatagtcta gctagtcacc atatctttgg tgttgataat gctaataaaa
    13981 tgttattttc tcctttagat aatgctaaaa atggcatgaa gatttatcta accgataaaa
    14041 ataaagttta tacttatgaa atacgtgaag tcaaacgtgt gacaccggat cgtgttgatg
    14101 aagttgatga tagagatggg gtcaatgaaa tcacattagt aacctgtgaa gaccttgctg
    14161 ctacagaacg tattattgtc aaaggtgatt tgaaagaaac aaaagattat tcacaaacat
    14221 ctgatgaaat tctaacagct ttcaatcaac catataaaca attttattaa tacaaatcag
    14281 tgaaatcatg gatttcactg attttttaag attttcataa aa
//
LOCUS       DAVHKZ010000047        13798 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000047 DAVHKZ010000000
VERSION     DAVHKZ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13798
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.047"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(44..856)
                     /gene="folK"
                     /locus_tag="VVO74_001870"
     CDS             complement(44..856)
                     /gene="folK"
                     /locus_tag="VVO74_001870"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEU5695854.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(899..1453)
                     /gene="folE"
                     /locus_tag="VVO74_001871"
     CDS             complement(899..1453)
                     /gene="folE"
                     /locus_tag="VVO74_001871"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU5695855.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVIIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(1434..2756)
                     /locus_tag="VVO74_001872"
     CDS             complement(1434..2756)
                     /locus_tag="VVO74_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU5695856.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDSPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(2758..3732)
                     /gene="folP"
                     /locus_tag="VVO74_001873"
     CDS             complement(2758..3732)
                     /gene="folP"
                     /locus_tag="VVO74_001873"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU5695857.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFNQTFTVEELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(3827..4534)
                     /locus_tag="VVO74_001874"
     CDS             complement(3827..4534)
                     /locus_tag="VVO74_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5695858.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(4587..6005)
                     /locus_tag="VVO74_001875"
     CDS             complement(4587..6005)
                     /locus_tag="VVO74_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU5695859.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            6195..7007
                     /locus_tag="VVO74_001876"
     CDS             6195..7007
                     /locus_tag="VVO74_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU5695860.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            7346..8365
                     /gene="adhP"
                     /locus_tag="VVO74_001877"
     CDS             7346..8365
                     /gene="adhP"
                     /locus_tag="VVO74_001877"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU5695861.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKGKTDGGAHSAVVTAVSKVAFNQAVDSVRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVAPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            8599..9588
                     /gene="manX"
                     /locus_tag="VVO74_001878"
     CDS             8599..9588
                     /gene="manX"
                     /locus_tag="VVO74_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU5695862.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQAAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            9616..10419
                     /locus_tag="VVO74_001879"
     CDS             9616..10419
                     /locus_tag="VVO74_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU5695863.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            10443..11354
                     /locus_tag="VVO74_001880"
     CDS             10443..11354
                     /locus_tag="VVO74_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU5695864.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(11410..12744)
                     /gene="pepC"
                     /locus_tag="VVO74_001881"
     CDS             complement(11410..12744)
                     /gene="pepC"
                     /locus_tag="VVO74_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU5695865.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(12961..13683)
                     /locus_tag="VVO74_001882"
     CDS             complement(12961..13683)
                     /locus_tag="VVO74_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU5695866.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DINTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     KPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
BASE COUNT         3965 a         3144 c         2738 g         3951 t
ORIGIN      
        1 aactctagcc ttcagttgca agtgactgaa aactagagtt tttctatttt ttcaaagcat
       61 catacaagtt gcggatcggt tgttttaata tcggatggat aaaatgaggc gcaatttcct
      121 gtaaggactc aaggacaaaa aggcgttccg ctatataagg atgaggcaat atgaggtcgt
      181 ctgtataaag gatctggtcc tccacaaaga gcaagtccaa atcaatcaaa cgaggtcccc
      241 aatgcacttc tctcacccgt cccagctctg actcaatggc taacaaggtt tctaacaagt
      301 cttgtgctgg tagccaggtt tccacctcaa ccacttgatt ggcaaagcta tcctgctcca
      361 ctccacccca aggctccgtc gctaagacac tggactcttt gagaatatgg atgccacgag
      421 ctcgcagttt gtcaatggct tgcttcaagt ttgcttgctt atctcccata ttgcttccta
      481 gggcgataaa ggctcgttgc ttgcggcgat gaatggttac cgagcaagta tctagtgaca
      541 aatgcaccgg tgcccaaggt tttttcagtt ccaacttcat ttcttggaca agaggataag
      601 actcaaaggt acgttccacc agtttatagg ctaccgtttc aatcaaatct tcactcgttt
      661 cctgaaacca agtcgtccac tgctgacaca attctccgta atggacagag gctgttaaat
      721 ccaagtctgt agctgccttg gtcatatcat aggataggat ggctgaaacg acaaatttct
      781 gccccaattc tttctcacta ggaaaaagac catgataggc aaacatttcc aaatccttaa
      841 tctgcagttg atccataatg attcctttct agaaaaatcc gcttgaaacg gattcttttt
      901 atagccccat taaacgataa gcttggtcgc ggaggtcctt atctgtttca aatagaccac
      961 gagctactgt cgtcaaggtt gcagtgcctg gttttctaac accacgcata ctcatacaca
     1021 tatgttccgc ctcaatgata acaaaggctc ctttagcacc tagatagtcc atcaaggcat
     1081 cggccacttc gatattcaaa cgttcttgaa tttgtggttt tttcgaataa acttcaaccg
     1141 tacgggctag cttagacaag cctgccacac gaccatctgg aatgtaggca atgtgcgctc
     1201 taccataaaa tggcaagaag tggtgttcac acatggtatg gaaaaagata tccttttcta
     1261 ccaccatatt atcgtcaata atttcaaagg attttgacaa atgttcctct gctgtttgac
     1321 caagacctga aaaaatctct tgatacatac gggctacacg agcaggtgtt tcctgcaaac
     1381 cctcgcgatt agcgtcctct cctacagcct cgataatcat ttttacagct gcttcaatct
     1441 tttgtgtatc cattctcgtt cttcctctcc atcagatagg ccctcacttg gctcaagaaa
     1501 tacaaggaac ctgtgacaat cctaactgtt tgtttctctt cttttttatc tgtcaaattc
     1561 tgctctagaa aatcatgcca atcttggtag ctgagatttc tagacttagc tgcctctttc
     1621 agcacgcttt catccgtcgc ccgactatcc gcaaaatgtg ttagagtaag ctcggtatct
     1681 ggcatggctc ccagcaagtc caacatatcc tccaaggcct tggttttgat acaagtgaag
     1741 aggatttcct tatgataatc cgcaaaacgt tcttgcaagg ttaccaacaa ggccttgata
     1801 gcatggggat tgtgggctcc atccaaaatc atcaagggat ctcttgacac gatttccaaa
     1861 cgccctggcc aacttgtttc ttccaaggct tgaccaagaa agtcattgct tgctagctct
     1921 cgaccatctt cttgacaaaa agtatcaagt aaagctatgg ccatcccagc attctctatt
     1981 tggtacaaac caagcaggct agtctggaag cgaccttgtc tgacagcact tgtatagtca
     2041 aagacttccc ctgtcaccac actttcttga tgacgaacct gataatctgt cccgtaggca
     2101 agtctcggcg aatctttccc ttccgcaatg cggtcaatca cagtcaaggc ttctggagca
     2161 atacgccctg ttaccaaggg catcccttgt ttgataatac ctgccttctg ctctgctatg
     2221 gcctccaagg tgtcaccaag tagggccaca tgatccaagc caatagttgt aattcctgtc
     2281 aaaatgggct gacagacatt ggtactatcc aaaagtccac ccatgccaac ttccatgatg
     2341 gccacatcta cttgctctga ggcaaagtag tcataggcca gggctgtgat aatctcaaac
     2401 tcggttgtgc cctgtaaatt ggcgaccgct tctccctcca gcaaagactg atagtctgcc
     2461 atgagagctt ctagcctcgc ttctgagatc gattccccat tgatgctaat ctggtctgtg
     2521 taatgaatga gatagggcga gctaaacacg ccaactctca gccctagctt ttctagcatc
     2581 tttttcaaaa aagcaatagt cgagcccttg ccgttagtcc ctccgatatg gaggaccttg
     2641 agtttgagat ggggattgcc acgcaaagct aacagttcca ccattcgttc caagccaaaa
     2701 tgcggttgat ccgtccggta gttagcaatc cactgattgt tttcaatttc tttcatctta
     2761 tttatattgc tttaaatcta aattttccgc ttcatcagcc agacgaatgg cagatgcaat
     2821 ttcaactgcc atcctgtgac tagctacgtc atgcacgcgc accacttcta caccctgtct
     2881 cgcagcgata ctagttacat gagccgaagc cgtgtcccga tttcggaaac caagctctgt
     2941 ctcaggattg acttcaaacc cactttcttc aaggatattg atgacaaatc gcttgcgcga
     3001 cactccgaga aagattggat agcccttctg atgtagttta tccagatccc gtaaaaggag
     3061 gagattttct ttcttggtca gaccaaagcc aattcctgga tccaacagga tattttctgg
     3121 tgcaatacca gcttctgccg ctctcgctag tgctcgttca aagaaagcca ccatcaagtc
     3181 ttcgattggc aatgtttcaa agtcagctaa ctcttctact gtaaaagttt gattaaatcc
     3241 aaaatgaggg aatatgagcg agctagggtg ttgaggtcgc gccataactg gattaaacat
     3301 gatgaccact tgcgctctcg cttcagctac cacatgagcc attttttcat cgcccatgag
     3361 accagtgata tcattaacta gattggcacc agcagccaaa gcagcctctg ctacttgact
     3421 cttccaagta tcaatagaga tgaggacatc actttccttg cgaatcgctt tgatcactgg
     3481 aacaacacgc tggatttcct cttctatctc aacatagcta ctgcccggcc gagtcgattc
     3541 tccgccgata tcgagcatac tggctccttc tgctatcaat ttacgagcct gctggagtgc
     3601 ctgctcaaga gcaaaaaatt gaccaccgtc cgaaaaggag tctggggtta cattgataat
     3661 tccgcaaata actgtctttg catgattggc tttacttgac atatcggtca ctccctcaag
     3721 gattttcatc atattatttt tctattttac cataaaaaga aaaagatgga cacgattgca
     3781 ttcatctttc cctagtagaa agaggtcggt ttctacataa aagcttttaa acagaaattc
     3841 ctaatgtccg actcataatc accacaagag ccaacaaaca gaaagcaatc ccattaacaa
     3901 tcatgtgaag caagatcgac atttccaaac gttgggtctt gtaggccgtc caagatagaa
     3961 ctgtcgacat acctccataa atcaataaag aaggtaaatt acttggttga tgcaataaag
     4021 caaacacaat cgtaccgact acaaatccca agttctcctt gcctcggaaa atctttttag
     4081 gaacaatccc acggcacaag atttcctcac aaatcggagc aagcaaggct agcaagaaga
     4141 aactggaaat caacgaacta ttttgaacca tatcgttaat ctgagactgg ttagctgttg
     4201 tcgtctcatt tgacagttgc aacaagatag aaccaagtat atttgacccg acaataacta
     4261 aataactcaa gcccaaacgt gccaaatctt tagctctaaa aaaagaaaaa ttaaaactag
     4321 ctaacttggt tttacgagct cccataataa atagagccag aaccacaatt gaaaggccag
     4381 caactatcag ccctgactgt agcagggcta cttcttttaa agtcaaaata gaggtaacca
     4441 ctaggggaac ctgatataaa aggacggcaa gtaaaaagac caaaatccag cctgcacgat
     4501 tcaacaattc tttccacata tttttctctt tcatcaccta tctcctttgt attaaaaaag
     4561 gggggaaatc cccctgggtc attctattat aaggccatgc tgatgtagtt aaggataaac
     4621 aaggcatcca aaatccaaat catggcatga acatctttaa cttgaccttt gacaagctta
     4681 gtcaaagtgt aagtcaagaa accaactgca atcccttgag tgatagagta gctgaatccc
     4741 ataaagatag atgtgaagaa ggcaggaact gcttcagaca tatcatccca atggatattt
     4801 ttcaagctac caagcatcat aatcccaacg ataatcaaga ttggagctgt agccgctgtt
     4861 ggtacgatcg ctagaagtgg gctaaagaag cttgaaatcg caaaacagat agctacaacc
     4921 aaggctgtca aaccagtacg tccacctgca ccgataccag cagcagactc aacataagtc
     4981 gttacgtttg aagtacctgc aatggcaccg actgtcgttc caatcaaatc agagtaaaga
     5041 gccttatcca atttggctga ttggtgattt tcaccatttg tcgctacaat accaactttt
     5101 tcacctgtac cgatcaaggt accaattgtg tcaaaaatat ctgtcaatga gaaggcaaga
     5161 atggccatca gagtttcagg caagcgagct gtatctgaaa ccaaagctcc caaaccttct
     5221 gaaccaagag ctgcaccaaa gattgtcttc aaatcttcaa aagctgcacc aacatggtta
     5281 ttagcaaaat cgatactaga caaatcaacc aaaccaactg caatagcaag aacagttgtt
     5341 gtcaagatag agagaataat tcccccttta atccctttga tgacaaagaa gatagtaatg
     5401 gcaagtcctg caagagccac taaaacagct ggattattaa agctgaccaa tcctggaact
     5461 gctgaagagt ttgctgcaat cgttgcttga gctttgtcag ccccttctcc tacaacagta
     5521 tagttgcctg gatcaatcgt gaatttcaaa agtccagcat tcttaatccc tacataggca
     5581 aggaagacac cgataccagc tgaaatagct gagcgaagag cattgggaat cgattcaatg
     5641 atcattttac gaacatttgt caaggtaata atcaatgaaa taatcccaca gatgaagacc
     5701 atagctaggg cttcttgcca agaataacca agcccgaata caactgtaaa ggtaaagaag
     5761 gcattgagtc ccatacctgg cgcttgggca taaggtaagt tagcataaaa agccatcatc
     5821 aaggtacccg ctactgcacc aataatcgtc gctaggaaga cgccctgagc aggcattcct
     5881 gtttgtgaaa gtatttgtgg gtttacaaag agaatatagc tcattgcaaa gaaagttgtt
     5941 aaaccagcga gaacctctgt acgaacgtct gtaccgttct cttttagttt aaataatttg
     6001 tccatcatca atctcctttt aatttttacg aacaataata gaattatatc atttatcatt
     6061 cactttttca atgtatttgt ttgatttgtt taagaaatta atccaatttc attttttgtt
     6121 tggaatctgc ttttctgcct gctttctgtt ataatagaag acatcttatc tgaaaacaca
     6181 ctagaaaggt ccatatgacg aaaaaaatta ttgcagttga cctggatgga accctgctca
     6241 actcagacag tcaaatttct gactttacca aaagaaccat caaaaaagtt gctgaaaaag
     6301 gccatcaggt tattattacg acaggtcgcc cttaccgtat gtcaaaagat ttttaccgtg
     6361 aactgggctt agacactcct atgattaact tcaacggatc ccttactcat ttaccagacc
     6421 aagtttggga ttttgaaaag tgtttgactg tagacaaaaa atatctgcta gatatggttc
     6481 aacgttcaga ggacattcaa gccgatttta tcgctggaga atatcgtaaa aaattctaca
     6541 ttacaaatcc caatgaagaa attgccaatc ccaaactatt tggtgtagaa gctttccagc
     6601 ctgaagatca attccagcct gaattggtga ccaaggaccc taactgtatc ctcttgcaga
     6661 ccagagccag tgacaaatat gccttggcaa aagaaatgaa cgccttctac cagcatcaac
     6721 tttctatcaa tacctgggga ggtccgctca atatccttga atgtacccca aaaggtgtca
     6781 acaaggcctt tgctttggac tacttgctca agataatgaa tcgtgacaaa aaagatttga
     6841 ttgcctttgg agatgaacac aatgataccg aaatgctcgc ttttgctggg aagggttatg
     6901 ccatgaaaaa tgccaatcca gagctactcc cttatgcaga tgagcaaatt tcccttacca
     6961 acgaccaaga tggggttgcc aaaaccctac aagacttatt cttataacct atactgatac
     7021 tcaatgagaa tcaaagagca aactaggaag ctagccgtag gttgctcaaa gcactgcttt
     7081 gaggttgtag atgaagctga cgtggtttga agagattttc gaagagtatg accagcttgc
     7141 aagctggtct ttgtgctctt ttcacagtct catcaaccag ttaatcgatt gttctacttt
     7201 ttgtctccaa aaccttggaa aaggctttct tttgtgatat acttcacata taaatacaag
     7261 agagctcgtc acactcgact ctgttgacaa aaaatcaatc cagtcccgtt gtccctgttc
     7321 tcggtcaata tcaaggagga tagctatgaa agctgttgtt gtaaatccag aaagcactgg
     7381 tgttgctatt gaagaaaaag tactccgtcc acttgaaact ggggaagcac ttgtagaagt
     7441 tgaatactgt ggtgtttgcc acaccgacct ccacgttgct catggtgact ttggtcaagt
     7501 cccaggacgt gttcttgggc acgaaggtat cggtatcgtt aaagagattg ctccagatgt
     7561 gaaaagcctt aaagtcggtg accgcgtcag cgttgcttgg ttctttgaag gatgtggcac
     7621 ttgcgaatac tgtacaactg gtcgcgaaac cctttgccgt acagtgaaaa atgctggcta
     7681 ctcagtagac ggtggtatgg ctgaacaatg tatcgtaact gctgactatg ctgtcaaggt
     7741 tcctgacgga cttgatccag cccaagcttc ttctatcaca tgtgctggag taacaaccta
     7801 taaagctatc aaagaagcaa aagttgaacc aggccaatgg gttgttcttt acggtgctgg
     7861 tggacttggt aacctcgctg ttcaatacgc taaaaaagta ttcaatgctc atgttatcgc
     7921 agtcgatatc aacaatgaca aacttgccct tgcaaaagaa gtaggcgctg acattgtgat
     7981 taacggcctc gaagttgaag atgtagctgg actcattaaa ggaaaaactg atggaggagc
     8041 tcattcagct gtcgtaactg ctgtgtctaa agttgccttc aaccaggctg ttgactccgt
     8101 tcgtgctggt ggtcgcgtcg tcgctgttgg tcttccttct gaaatgatgg aactcagtat
     8161 cgttaaaaca gtcctcgatg gaatccaagt catcggttct cttgtcggaa ctcgtaaaga
     8221 cttagaagaa gccttccaat ttggtgcaga aggtctggta gccccagttg ttcaaaaacg
     8281 tccagtagaa gatgctgttg ccattttcga cgaaatggaa aaaggtcaaa tccaaggacg
     8341 tatggtactc gacttcaccc actaatctaa tagaaaccta ttttaaaagt tggaagcttc
     8401 ttctaacttt tttatattaa atttttaaat aagaattcaa gattactcct taaaaactca
     8461 acatatcaac atataaaaat aaaaattttt taatttttta tgataaatag ttgctttttt
     8521 tatgaaaacg gtttatactt aaacagtctt aaagttttct taaatgaaaa ctaaaacaaa
     8581 aaaggaggaa tgacaataat gagtatcgga atcattattg cgagccacgg cgaatttgct
     8641 gcgggtattc atcagtcagg atctatgatc tttggtgaac aagaaaaggt tcaagttgtg
     8701 acctttatgc caaatgaagg tcctgatgat ctatacgcta agtttaataa cgctgttgct
     8761 gcatttgacg cagaagatga ggttctagtt ttggctgacc tttggagtgg ttctccattt
     8821 aaccaagcta gtcgcgtgat gggagaaaat cctgagcgta agtttgccat catcacagga
     8881 cttaacttac cgatgttgat tcaagcctac acagagcgcc tcatggacgc tgctgcaggt
     8941 gtagaaaaag tcgctgctaa tatcattaaa gaagccaagg atggcatcaa agctcttcca
     9001 gaagagctaa atccagttga agaagttgca agcgctgcag ctgctccagt tgcccaagct
     9061 gctatcccag aaggaactgt tatcggagac ggtaaattga aaatcaatct tgcccgtctt
     9121 gacacacgtc tacttcacgg tcaggttgca actgcttgga ctccagattc aaaagcaaat
     9181 cgtatcatcg ttgcttcaga taacgtggct aaagacgacc ttcgtaaaga attgattaaa
     9241 caagcagctc caggtaatgt caaggctaac gtggttccaa ttcaaaaact gattgagatt
     9301 tcaaaagacc cacgttttgg agaaacacat gcccttatct tgtttgaaac acctcaagat
     9361 gcccttcgtg ccatcgaagg cggcgtgcca atcaagactc ttaacgttgg ttctatggct
     9421 cactcaacag gtaaaacatt ggtcaatacc gttttgtcta tggacaaaga agatgttgcg
     9481 acatttgaaa aaatgcgtga cttgggtgtt gaatttgatg tccgtaaagt accaaatgat
     9541 tctaaaaaag atttgtttga cttgattaac aaagccaatg tcaaataagc cattatttat
     9601 gaaaggattt taaacatgtc tattatttct atggttttag tagtcgttgt agccttcttt
     9661 gcaggtcttg aaggcatcct cgaccagttc caatttcacc aaccacttgt agcctgtacc
     9721 cttattgggc ttgtaacagg tcacttggaa gcagggatta tcctcggtgg atcgcttcaa
     9781 atgattgccc ttggttggtc aaatatcggt gctgctatcg ctcctgatgc tgcacttgct
     9841 tctgtcgctg ctgccattat catggttctt ggtggtgact ttaccaagac tggtatcggt
     9901 gttgcccaag cggttgctat ccctcttgcc gtagctggac ttttcttgac aatgattgtt
     9961 cgtacaattt cagttggttt ggttcatact gcagatgctg ccgctaaaaa aggtgacttc
    10021 ggcgctgtgg agcgtgcgca tttcattgcg ctactcttcc aaggacttcg tatcgcgctt
    10081 cctgcagctc ttctccttat ggtaccaact gaaactgtac aaagtatcct tagtgccatg
    10141 ccagactggc tcaaagatgg tatggctatc ggtggtggta tggtcgttgc cgttggttac
    10201 gccatggtta tcaacatgat ggcaactcgt gaagtatggc cattcttcgc tcttggtttc
    10261 gttctcgctg ctgtgtcaga tattactcta atcggattcg gtgctatcgg tgttgctatc
    10321 gctcttatct accttcacct ttctaaaact ggtggaaatg gtggcggagg agccgcaact
    10381 tctaacgacc caatcggcga tatcctagaa gactactaag ataagaaagg actgaaaaca
    10441 tcatgactga aaaacttcaa ttaactaaat cagatcgtaa aaaagtttgg tggcgttcaa
    10501 ccttcttaca agggtcttgg aactttgaac ggatgcaaaa cttgggctgg gcttatacac
    10561 tcattccagc tatcaaaaaa ctctatacta aaaaagaaga tcaaatcgct gctcttgagc
    10621 gtcaccttga gttcttcaac actcatccat acgtagctgc tccagtcatg ggggttactc
    10681 ttgcgcttga agaagaacgt gctaacggtg tggaaatcga tgacgctgct atccaagggg
    10741 tcaaaatcgg tatgatggga cctcttgctg gtatcggtga cccagtattc tggtttacag
    10801 tacgcccaat ccttggatct ctcggtgctt cacttgccct tactggcaat atcttgggtc
    10861 cactcctctt ctttgttgca tggaacttga ttcgtatgtc attcttgtgg tatgttcaag
    10921 agattggata caaggctgga tcagaaatca ctaaagatat gtctggtggt atccttcaag
    10981 atatcactaa aggagcttct atccttggga tgttcattct tgctgtcctt gttcaacgct
    11041 gggtaaatat taaatttgct ttcgatgttt ctaaagttca actagatgaa aaggcttata
    11101 tccattggga taaattgcca gaagggtcta aaggtatcca agaagcattc gcacaagtag
    11161 gacaaggatt gtctcaaact cctgaaaaag ttactacttt ccaacaaaac ttggatatgt
    11221 tgattcctgg attatcagga ctactcctta ctttactttg catgtactta cttaagaaaa
    11281 aagtatctcc aatcactatt atccttgccc tcttcgcagt gggtattgtg gcacatgttc
    11341 ttcacatcat gtaatcaagc aactaaaaag gaaccaggtt ctaaaatctg attccttttt
    11401 tctatgcttt tattcagcca aggctcccat tggatcccat ggtgcaagta caattggttc
    11461 tgctccatag gcagcttgtt cttctgctgt cagcaattcc ttacgaacaa cgatttggta
    11521 tgtgtattcg tccatccaag cgtctgaggc aacaaagtaa ccatctgtac cgaccttgtc
    11581 tccccatgag ttttcaacct tccacttggt tgatttacca ttttcgtcca agtcaacacc
    11641 tgtcaagacc atggcgtggg tcatcaagct ttcgctatag tccaaacgtc cagccttgtc
    11701 ttgagtaagt ttaatgtcca tgcttgattc aaagtcataa acatctgtcg caaggatgcc
    11761 agccttacgg ttactgagct ggccgacatc agaaccaaac caaacagtct cacctgcttg
    11821 catttgggca atcgccaatt ctttcaagcg ctccattgga acgttgatgt aacgaactgc
    11881 acggctacca accacattcc ccaacatctc aactgtgtaa gattttccgt aaggtttatc
    11941 agcagttgga gcattgataa cagaaacgta gtcttctaaa ggaagattga catatttctt
    12001 gtaaaactct tgtggtgtga ttcctttttc acttttgtag ttgttatctt tatcgcgata
    12061 agcaaagtca aacttgcgtg gtggaagtcc taatgacata gcaagaaagt taaagatttc
    12121 ttgcaagagg tcttctttct tagcttgaac agtcgcttga tctgcaccag aaacaagcaa
    12181 gtcacgcaag atttgagcat cttgacgaag caatttatta aggatcgcat ttagctcacg
    12241 actgctgcta gatgaaacag actcaggata aactgactta ggcacgacac cgtatttttc
    12301 aaagagggaa acgaccatat cccattgacc accatcttgt tgaggtgttt ggagtaagaa
    12361 gctaaccttg cggctagtca attcttggtc tgaagtcgca atgacttgct ccaagaacca
    12421 gtttgatttc tcatacttat cccagaagaa agtgtgggct tgtgacaact caaagttctc
    12481 caatttgtat tgcgagatga gtttgtggcg gaaggtgttg agagccgcaa acatccagca
    12541 acgaccagac gctttctggt tagtgacctt gtccttggtt aaatccaatg agaaaacagg
    12601 tgtgttgtct acatggcttt ggcgacgttc cagagctgca aaaattccgt tgtggctagc
    12661 agcattttca atcgcttggt attttacatt tgcttcatag ttggcaaata gtttatcagt
    12721 aaatgattct tgaatcgcgt tcatagattc ctccttttat tctacagtct attataactc
    12781 ttttcacaaa ggaagcaact aaaaaacata aaaggtaagg acattctccc tcaccttttt
    12841 cgaatatata ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg ccgtactcaa
    12901 gtacagcctg cggctagttt cctagtttgc tctttgattt tcattgagta ttaaactaaa
    12961 ttaaataata ttagcgcgga gaatttctaa ttcttccttg gtcaagcgac gccattcccc
    13021 tcgttccagg ttctcatcta atactaaagt tcccatagtc aatcgttgca agtccaccac
    13081 ttccttgcca cagtagccca ccatacgctt gatctgatga aacttccctt ctgcaatggt
    13141 cacacggatt tggctttgat tcttttctgt atctatggat acaagctcca gtatagcggg
    13201 tttacaggta aagtctttga gaggaatacc ctcagcaaat gtctccacat cttcttgggt
    13261 catgattccc ttgacttgtg ccagataagt cttgtccaca tgacgcttgg gcgaaagaag
    13321 aacatgagcc agctgaccat cattggtcaa gagcaaaaga ccatgcgtgt taatatccaa
    13381 gcgtcctact gggaaaactt ccttactccg cgccaagtca tccaacaagt ccagaacggt
    13441 tctgtgcttg ggatcctcag tcgctgagat aactcctttg ggcttgttca tcatgtagta
    13501 gacaaactct tcatactcca acacttgccc atcaaagcga atctcatcta ttttttcatc
    13561 aatctgcaat ttagctgatt tttctttttt accatttaca gtcacgcgcc cagccttgag
    13621 caagtttttg acctcagtcc gacttcccac cgcacaggca actaaaaatt tatctaatct
    13681 catagaacta ttatatcata tcaaaaggag gctggtacaa tgaccaacct ccttttcgtt
    13741 tcatactctt caaaaatctc ttcaaaccgc gtcaacgtcg ccttgccgta tatatgtt
//
LOCUS       DAVHKZ010000048        13774 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000048 DAVHKZ010000000
VERSION     DAVHKZ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13774
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.048"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(81..395)
                     /gene="trxA"
                     /locus_tag="VVO74_001883"
     CDS             complement(81..395)
                     /gene="trxA"
                     /locus_tag="VVO74_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU5695867.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(412..633)
                     /locus_tag="VVO74_001884"
     CDS             complement(412..633)
                     /locus_tag="VVO74_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU5695868.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(732..1112)
                     /locus_tag="VVO74_001885"
     CDS             complement(732..1112)
                     /locus_tag="VVO74_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU5695869.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(1255..2208)
                     /locus_tag="VVO74_001886"
     CDS             complement(1255..2208)
                     /locus_tag="VVO74_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU5695870.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(2276..3487)
                     /gene="sstT"
                     /locus_tag="VVO74_001887"
                     /pseudo
     CDS             complement(2276..3487)
                     /gene="sstT"
                     /locus_tag="VVO74_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012962425.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            3626..4186
                     /locus_tag="VVO74_001888"
     CDS             3626..4186
                     /locus_tag="VVO74_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEU5695871.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQVLHFVPNRNITVVSNFSRTD"
     gene            4243..5151
                     /locus_tag="VVO74_001889"
     CDS             4243..5151
                     /locus_tag="VVO74_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU5695872.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            5103..5693
                     /locus_tag="VVO74_001890"
     CDS             5103..5693
                     /locus_tag="VVO74_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU5695873.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            5696..6802
                     /gene="yqeH"
                     /locus_tag="VVO74_001891"
     CDS             5696..6802
                     /gene="yqeH"
                     /locus_tag="VVO74_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU5695874.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPSLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            7016..7327
                     /gene="yhbY"
                     /locus_tag="VVO74_001892"
     CDS             7016..7327
                     /gene="yhbY"
                     /locus_tag="VVO74_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU5695875.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            7379..8008
                     /locus_tag="VVO74_001893"
     CDS             7379..8008
                     /locus_tag="VVO74_001893"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU5695876.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVAYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            8008..8601
                     /gene="yqeK"
                     /locus_tag="VVO74_001894"
     CDS             8008..8601
                     /gene="yqeK"
                     /locus_tag="VVO74_001894"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU5695877.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            8602..9102
                     /locus_tag="VVO74_001895"
     CDS             8602..9102
                     /locus_tag="VVO74_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU5695878.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            9115..9468
                     /gene="rsfS"
                     /locus_tag="VVO74_001896"
     CDS             9115..9468
                     /gene="rsfS"
                     /locus_tag="VVO74_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU5695879.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            9571..10317
                     /locus_tag="VVO74_001897"
     CDS             9571..10317
                     /locus_tag="VVO74_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU5695880.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            10327..11424
                     /locus_tag="VVO74_001898"
     CDS             10327..11424
                     /locus_tag="VVO74_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU5695881.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQSMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            11662..11892
                     /locus_tag="VVO74_001899"
     CDS             11662..11892
                     /locus_tag="VVO74_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEU5695882.1"
                     /translation="MEGVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMDKIRAGH"
     gene            12161..13774
                     /locus_tag="VVO74_001900"
     CDS             12161..13774
                     /locus_tag="VVO74_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU5695883.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
BASE COUNT         4162 a         2675 c         3167 g         3770 t
ORIGIN      
        1 ctatagtcta gcatattttt tgaaaaatgg caaagggcaa gaaaaaagag accaaagaaa
       61 gtacttggtc tctcgtttga ttagctcaat tcagcaatga tggccttgat ttgttctgct
      121 gtgtgaacac ctgcaacttg tttgacaact tggccgtctt ttttgaagag aagagttgga
      181 atagacatga ttccaaaagc acgagctgtg tttggatttt catcaacgtc cattttaacg
      241 attttcaaga catcttctga aagttcttca gacaatttgt ccaagattgg accttgcata
      301 cgacatggac cacaccaagt tgcccagaag tctactaaga ccaaaccgtc ttttgtttct
      361 tgttcgaatg ttgcatctgt aattgctttt gccattgtat ttctcctttt tttagttata
      421 ttggcttaaa tcttgtttca tgagatagaa gaagatatct ccataagtcc catggtagtc
      481 caaattatga cccttgtaag ttaatttttg gacagggtag tagtctgcga cgccgataag
      541 gcaagcttgt tgcgaacgtt caaagtcttc ataagactcg aaagtcacag ttctttcgtt
      601 cttgctggca tctatatagg taatttcaat catgtttaaa actcctttgt ttaatgctaa
      661 ctttatttta ctccttataa aagagaatgt caagaaaaat gattgcgcac gcaacttttt
      721 ttaaaatcat cttaaatcaa gaaatccaaa cctgcttcca agctttcttc gacagtcttt
      781 tgtagcgagg ccagtgtctt ttgcccatca tttgtcaggc agataaaact agagcgtcta
      841 tcttgatggc aacacatgcg actgagtaga ccgcaatttt tagcttccaa gcgagccacc
      901 atcctagaaa ctgcgctcgg gctcagatga agcttatctg gcaggtcaat ctggcgtaga
      961 gatttttctt cagccaagtc cagatagtag agcaggtaga actctttcaa ggtcagactt
     1021 tgctcgctct gttgggcaat ggtctcttcc aagagacttt caatttcttt ctgacgccga
     1081 ttgaagtcaa accatttttc caaataggtc atagtgtctc ctttcttttt agagtcataa
     1141 atagaagaaa gtccattaac gggcagtctc tgcgtcacaa gatgattgcg catgcaataa
     1201 ttatactact tttcaagaat gctggcaagc tctgtttttt agtggtttta ttttttactg
     1261 tctatatttt tggtaaaaat caacttttac ttggatgaag gttttggctt cacgtaggag
     1321 ttgaagaagg gtggcgcggg tttcaaactc ttctcttgtt ttgggcagac tgcggttccg
     1381 gaagacttcc agataacgtt caatttcatc tagcaaatca gaagcaggat tggtctggct
     1441 cagttgacct gcaatttttg aaaagagttg cgctaagatc aggctttcac tggcggcaag
     1501 gtgacaagtg ttaatctgtt gggccatgtt tctcaggata cgactttgtc gctgtctcat
     1561 ctcaaagtag tggatatggt agtcggtctg gtgaaagagg tggtcagagt gatccaaata
     1621 gaccagtctg agggcttctt tcaaaagcgt gtctaattct gctaccagct gtgctcggtt
     1681 gcgtccgtct cctctggata aatagtattt gaagcgctgg aggatatctt ttaacttttc
     1741 ttccaccagc gtgtggtagt gctggatttc ctcttctcgt gaaggcatat agagattaac
     1801 aagcaaggca aatcctgtac caatagcaaa gagaaggaat tcgttgacta ggaggtctgg
     1861 agaggttgac tcttgaacca agagatggct aaccaaaacc gtgcttggtg tgatgccaat
     1921 ttcccagccc atcttgtagg ctaaaggaac gtagaaggcc agatagaggc cgagactcca
     1981 gatatgaaat ccgctcaagt gaaaagctag aacaccgata gccagagcta gaagcataga
     2041 aaaaagacga ttgcgagcca gttttaaagt acttctacgc gtatcagata ggctcaagag
     2101 agcgataatt ccagccgaaa ctgctgacga aagattgaga aaataagcaa gcaggcaggc
     2161 aagacaggta gctaagatga gcttggtcgt acgttggcta atagacataa gaatttccta
     2221 ataagttaga ataaaagcgt aaaagacaag acatgagcag gcttgccttg atgagttatt
     2281 ttttacgggt tgctgcgtat tcggcaacgg cggtaaagag gacatctgta gaagaattaa
     2341 gggctgtttc acatgagtct tggatgacac caatcacaaa accaacccca acaacttgta
     2401 tggcaatatc gttagaaata ccgaaaaggc tacaagcaac tgggataaga aggagggaac
     2461 ctccggcaat acctgaagca ccacaggctg agatagctgc taccacactg aggacaaagg
     2521 ctgtggcaaa gtcaacagga attccaagag tgttaactgc agcaagggtc aaaaggttaa
     2581 tggtaatcgc tactccagcc atattgatag tagaaccgag tgggatagaa acagaatagg
     2641 tatctgggtt gagtccaagg tcatggcaga gtttcatgtt gacaggaatg ttagtcgcag
     2701 aactacgagt gaaaaaggct gtcacaccgc tgacacggag gcagttccaa actagagagt
     2761 aaggattgcg tctcataaag aagaaggcaa tcaaagggtt gaccacaggg gcaacaaaaa
     2821 gcatagtcgt tactaatgga accaataaaa taccgtagtt ggcaaggctt ccgactccct
     2881 tgtcagaaat ggttttaaaa acaagaccaa ggattccaaa tggagccaga ttgatgatcc
     2941 attcgacaat tttagaagtc acgtcagcga tagtttttag caattcttta ctatttttac
     3001 tggcttctct catagcgatt ccaaaaatga ctgcccaaga taagattcca atatagttag
     3061 cagtaaacag ggcgcgttga ctgggctgtc aaccagtttg agcaagaggt tgctgaggat
     3121 ctgcccaacc ccatctggtg gtgcaatttc agtattggca ctatttaggg taatttcaat
     3181 agggacgatg aaacttgcta gtacagctac aagagcagcg gcgaaagtcc ctatcatagg
     3241 atatacaaga aaacaacagt tttcatattg ctatcttgtc ccttttgatg ttgggaaagg
     3301 gcattggcaa cgagggcaaa gactaggata ggagcaacag cttttagacc tccaacgaat
     3361 aaatccccga gtagcccaat ccctgagaga ttaggaaggg tcagtcctag gattccccac
     3421 aaagcatacc aatcaagata cgcttgacaa ggcttgcctt attccaagca tgaatgattc
     3481 ttttcataat aatctccttt ttgtgtagtg attatgatta tagtataaat gatagacaaa
     3541 atcaagaatt ttctgtctat tttttgaata tttatggaga atgagactga tgaaaatatg
     3601 gtataatgaa ataaaggagt tttatatgca aaaatttatt caggcttata ttgaaaagct
     3661 agatgtgaca accattatcg agaatattct aaccaaggtc atttctcttt tactgctttt
     3721 gattgtattt tatattgcta aaaaaatgct tcataccatg gtgcagagaa ttgtcaaacc
     3781 ttctctaaaa atgtctcgtc atgatgttgg acgccaaaaa accatctcac gtttactaga
     3841 aaatgtgttt aattatacgc tatatttctt tttactctac tgcattttgt cgattttagg
     3901 tttgccagtt tctagtttgc tggctggagc tggtattgct ggggtagcga ttggtatggg
     3961 agcccaaggc tttctgtctg atgtcatcaa tggctttttc atcctctttg aacgtcaact
     4021 ggatgtggga gatgaggtcg ttctgacaaa tggaccgatt actgtatcgg gtaaggttgt
     4081 cagtgtggga attcgtacga cacagcttcg tagcgaggag caagtccttc actttgtccc
     4141 taaccgaaat atcacagttg ttagcaattt ctcacgcaca gactagacct gttattttaa
     4201 gtaatttgtg gtacaataga gggagtttaa taaggagaaa agatggtttt agaaaagcag
     4261 ttgggcaatg gttgtacctg gatagaccta gacctaggaa agttgaataa actagaagac
     4321 ctttctgaaa tttacggttt ggacaaggaa accattgaat acgcactgga tagaaacgag
     4381 cgcgcccaca tggactacca ccgtgaaagt gggacggtta cctttatcta taatgtccta
     4441 gacgtaaaaa aggacaaggc ctactatgag acttttccca tgacctttat tgtcgagcat
     4501 cgtcgcctga ttaccattag taataccaag aacgcctatg tcattgaaca gatgactcgt
     4561 tatctggaga gccatgacac gctttcgatt tataagtttc tctttgccag tctggaaatt
     4621 atcagcaatg cctactatcc tgtcattgag cagatggaca agagtaggga tgaggtcaat
     4681 gacctcttgc gccagcgaac taccaagaaa aacctctttg ccctgtctga tttggagact
     4741 ggtatggttt atctgacggc agctgccaaa caaaatcgga ttttgttaga gcatattcaa
     4801 ggtcatgcct tgtatcgtag ttttgatgag attgagagag aacagtttga tgatgccatg
     4861 attgaggctc atcagctggt atccatgaca gacctaatct ctcagatttt acagcagctt
     4921 tcagcctctt acaacaatat tctaaacaat aatctgaatg acaatttgac aaccttgact
     4981 atcatttcag tcttgctagc tgttttggca gtcgtgacag gctttttcgg aatgaatgtt
     5041 cccttacctt taacagatga gccccatgct tggctctata tcagtttggc tagtgcaggt
     5101 ttgtggattg ttttatcctt gttactaagg aaaattgcga aaaaaagtta agaaaaggag
     5161 ccagaatggc gattgaaaat tatataccag attttgctgt ggaagcagtc tatgatctga
     5221 cagtcccaag cctgcaggcg cagggaatca aggctgtttt ggtcgatttg gataataccc
     5281 tcattgcttg gaacaaccct gatggaacgc cagagatgaa gcaatggcta catgaccttc
     5341 gggacgcggg tattggcatt atcgtagtgt caaataacac caaaaaacgc gttcaacgag
     5401 cagttgagaa atttgggatt gattacgttt attgggcctt gaagcccttc acatttggta
     5461 ttgaccgtgc tatgaaggaa ttccactatg acaaaaagga agtggtcatg gttggtgacc
     5521 agctcatgac agatatacga gcagcccacc gtgcagggat tcggtcaatt ttagtcaaac
     5581 ccttggtcca acatgactca atcaaaacgc agattaaccg aactcgtgag cgtcgtgtta
     5641 tgagaaaaat cactgaaaag tacggaccga ttacatataa aaaaggaatt taactatgga
     5701 agaaattctc tgtattggtt gtggagcaac cattcagacg acagataaag ctggtcttgg
     5761 ttttaccccc cagtcggcac ttgaaaaagg tttggagact ggcgaagtct attgccaacg
     5821 ctgtttccgt ctccgccact acaatgaaat cacagatgtc cagttgacga acgatgattt
     5881 cctcaagctc ttgcacgagg tgggagacag tgatgcttta gtggtcaatg ttattgatat
     5941 ctttgatttt aatggatctg tcatcccagg tttaccacgt ttcgtctcgg gcaatgatgt
     6001 cctcttggta ggaaataaaa aagatatcct tcctaagtca gttaagtctg gtaagattag
     6061 ccagtggctc atgaaacgtg cccatgaaga aggtcttcgt ccagtcgatg tggtcctaac
     6121 ttcagcacaa aataaacatg ccattaagga agtcattgac aagattgaac actaccgtaa
     6181 gggccgcgat gtctatgtgg tcggtgtgac caacgttgga aaatcaactc taatcaatgc
     6241 tattatccaa gaaatcacgg gtgatcagaa tgtcatcact acttcacgct tcccagggac
     6301 aaccttggac aaaatagaga ttccgcttga cgacggatct tatatttacg atacgccggg
     6361 aattatccac cgccaccaga tggctcacta cttgacggcc aaaaacctca agtatgtcag
     6421 tcctaaaaag gaaatcaagc ctaagaccta tcagcttaat cctgagcaaa ccctattttt
     6481 aggtggtttg ggacgctttg actttatagc aggagaaaag caaggattta ctgctttctt
     6541 tgataatgaa ctcaaactcc atcgtagcaa gcttgaagga gctagtgctt tctacgataa
     6601 gcacctggga actcttctga caccaccaaa tagcaaggaa aaagaagatt tcccaagtct
     6661 agtccagcat gtctttacca ttaaagataa gacagaccta gtcatctcag gcctaggctg
     6721 gattcgtgta acaggcatag caaaagtcgc cgtctgggca ccagaaggcg tcgccgtcgt
     6781 cacacgaaaa gcaattattt aaaacaaaat cgctgagcga acaaagtgag ctcatatagc
     6841 gatagttatt gccgtggtgt gattgccaat ctgtagattg gcaaggggca caattgagac
     6901 caaggctcaa ttgtgaggtc aggaaatcca tttttcaaag atgaaatctt tggaaaatta
     6961 gttccgaccg tccctcacca cctaaaataa ctatccaaaa acaaggaaga aaattatgtc
     7021 attaacatca aaacaacgtg ccttcctcaa cagccaggca cacaccctca aacctatcat
     7081 ccaaatcggg aaaaatggac tcaacgacca aatcaaaacc agcgtccgtc aagctcttga
     7141 tgcgcgtgaa ttaatcaagg ttactctctt acaaaacaca gatgaaaaca tccacgaagt
     7201 agctgaaatt ttggaagaag aaatcggtgt ggatacagtc caaaaaatag gacgcatctt
     7261 gattttgttt aaacaatcta gcaagaaaga aaatcgcaag atttctaaga aagtcaaaga
     7321 aatctaagac cgaaactcca aataactgtt tttatagaga aataaagggg actagcctat
     7381 gacaatcgaa ctattgactc cctttaccaa ggtagagttg gagccagaaa tcaaggagaa
     7441 aaaacgcaaa caagttggga ttttaggggg gaattttaac cctgttcaca atgcccatct
     7501 cattgttgcg gatcaagtac ggcaacagtt gggactggat caagttcttc tcatgcctga
     7561 ataccaacct cctcacgttg ataaaaagga aaccatccct gaacaccatc gtctcaagat
     7621 gcttgagttg gcaattgagg ggattgacgg cctagtcatt gaaaccattg agttggagcg
     7681 caagggtatt tcctacacct acgataccat gaagattttg acagagaaga atccagatac
     7741 ggattattac tttatcatcg gtgccgacat ggttgcctat ctgcctaagt ggtaccgaat
     7801 tgatgaactg gttgacatgg ttcagtttgt gggggttcag cgtccacgct acaaggtagg
     7861 gacttcctat ccagttatct gggtggacgt accgctcatg gatatctcgt ccagcatggt
     7921 gcgggacttc cttgcccaag gtcggaaacc caactttctc ctacctcagc cagtgctaga
     7981 ctacatcgag aaggaggggc tctactgatg tcctatcaag actatatcaa ctgctcccgt
     8041 gaggccttgt tggaaaaaat ggcagagctt ctacctgaga aacgtctaac ccattgtcta
     8101 ggtgtggagc gtgccgctat ggaattagct cagcgctttg gtgtagatgt tgagaaagca
     8161 agtctagcag gtcttcttca tgactatgct aaaaagttgt cagatcagga atttctagcc
     8221 ttgattgacc gttaccagct agaccctgac ctcaaaaact ggggcaataa tgtctggcat
     8281 ggtatggtcg gaatttacaa aattcaggaa gatttggatt tgcatgattc agaaatcctg
     8341 cgagccattg aagtccatac agtcggtgct ggtcaaatga cagacctaga taaggtcatc
     8401 tacgtcgcag actatatcga gcacaatcga gcctttcctg gagtagatgt ggcgcgtgag
     8461 attgcaagtc tatcgctcaa taaggcggtg gcctacgaaa cagctcgtac cgtggagtat
     8521 ctagctcatc agggattccc catatatccc caaacccttg aaacctataa cgcctttgtg
     8581 cactatttga aagagaacta aatgaagacg gcttttataa tcattgatgt tcagaatgtt
     8641 ttagtagaaa ctgggttcca gacaaaaagt ctattgggaa aaatttctta tttacaaaac
     8701 caggctagaa gcaagaatat tgaaattatc tatgttcaac atattgagaa ctctgaagct
     8761 caaacatcag aagattggca gttatctgcg cttttaaatc gaaaacctgc tgaaaaggtc
     8821 tttcagaaga agtataacag tattttcaaa gaaactggct taaaagaata cttggataag
     8881 caggggattg aaaaattagt tttatgtggt atgcagacag aatattgtgt ggatacctct
     8941 gtcaaggttg cctttgaata tggctatcag cttattgttc cagaaggtgc tgtcacaacc
     9001 tttgatgggg atgacattcc agcagaaacg attaatgaat tttatgagga catttgggag
     9061 gagcgctttg cagatgtcct agattacaaa catattttct aaaaagagga ttaaatgaac
     9121 gaaaaagaat tactagaact agtcgtgaaa gcggctgatg agaaacgtgc ggaggatatc
     9181 ctcgcacttg atgtacaaga tttgactagt gtgacggact actttgtcat cactagctca
     9241 atgaatagcc gtcagttgga cgctatcgca gctaatatcc gtgaaaaagt agctcaagcg
     9301 ggctttaaag gtagccatgt cgaaggcgat gcagctggag gctgggtctt actggacctc
     9361 ggtgctgttg tcgtgcatat cttttcagaa gaaatgcgtg cccattataa tctagagaag
     9421 ctatggcatg aggcgaattc agtagatatt tcagaagctc ttgcttagaa gatgaactca
     9481 gttgtagtca actgggtttc tttgcttatt ttagaaaaat tgatagaaag gtaaagggct
     9541 agtggtgttt accatggagc tcttagtatc atgattatgg cgacttatga aacctttgcg
     9601 gcggtctatg atgcggtcat ggacgatagt ttatacgaca aatggacaaa tttttctctg
     9661 cgtcatttgc ctaagaccaa ggagaaaaag aaactcttgg aactggcttg tgggacagga
     9721 attcaatcag tgcgcttctc tcaggctggt tttgatgtga ctggacttga cttgagtgcg
     9781 gatatgttga agattgcgga gaagagagca acttcagcca agcaaaagat tgcttttata
     9841 gaaggtaata tgctgaattt gtccaaggca gggaaatacg attttgtcac gtgttattcg
     9901 gactctatct gctatatgca ggatgaggtg gaagtagggg acgtctttaa ggacgtgtac
     9961 aatgcgctga atgaagaggg agttttcatc tttgacgtgc actcgaccta ccagacagat
    10021 gaagtattcc ctggctattc ctaccatgaa aatgcggaag attttgccat gctttgggat
    10081 acatatgagg acgaagctcc tcactccatc gtgcatgagc tgactttctt tatcaaggag
    10141 gctgacggtt cctttagtcg ccacgatgaa gtacatgagg agaggaccta tgagatcttg
    10201 acctatgata tcttactgga acaggctgga ttcaagtcct tcaaactcta tgcagacttt
    10261 gaggataagg aaccaacaga aactagcacc cgttggtttt ttgtggcgca gaagtaggag
    10321 attagcatga ccatcacagg tattatcgcg gagttcaatc cttttcataa tggccataaa
    10381 tacctgctgg atcaggcaga gggactgaaa attgttgcca tgtcagggaa tttcatgcag
    10441 cgtggagagc ctgctattgt ggataagtgg acaagggccc agatggcgct ggaaaatggc
    10501 gcagacttgg tagtggaatt gcccttttta gtcagtgttc aggcagctga tttctttggt
    10561 caaggagctg tggatatctt ggatcgcttg ggcattgata gtctagtttt tgggacagag
    10621 gaagttcgag attatcagaa aatcgctgac ttatacacag agaaaggtgc tgagatggag
    10681 aaatttgtgg aaaatctgcc tgattccctt tcctatcccc agaaaaccca atctatgtgg
    10741 aaggaatttg ctggtcttga tttttcaggt aataccccca atcatgttct tgctctggcc
    10801 tatgcaaagg cggttgcagg acgaaatatc aagctgcatc cgattcagcg tcagggggca
    10861 ggttaccatt ctgtgaataa agatgtggac tttgcctcgg cgacagccct ccgtcaacat
    10921 cagaaggacc aagatttctt agaacgtttt atgccttctg ttgccctatt tgagcaggcc
    10981 agtaaggtga tctgggaaga ctattttccc ttgctccgct atcaaatctt gtcaaatccc
    11041 gacctaacca ccatctatca ggtcaatcaa gaaatggctg tgcgcattaa agaagctatt
    11101 aaaacagccc agtctgtgga agaattggtc gagttagtga ctaccaaacg ttacaccaag
    11161 gcgcgtgtca gacgcctatt gacctatatt ttggtgcagg ctagggaaaa tgtcttgcca
    11221 gaagccattc atgtccttgg atttactgaa aaaggcaggc aacatctcaa gtctctgaaa
    11281 ggacaggtca atctagtcag ccgaattggc aaagaacctt gggatgctat gacccaaaaa
    11341 gcagaccaga tttaccaact aggaaagcca agtatagcag agcaaaattt tggaagagtg
    11401 ccgattagaa tagaaacaaa ctaagtctac taaaaggtag gctttttgag attttttacg
    11461 aataatactc ttcgaaaatc aaattcaaat cgcgtcaacg tcgctttgcc gtactcaagt
    11521 acagcctgag gctagtttcc tagtttgctc tttgattttc attgagtata aatagataga
    11581 aaagaaaatc ttgtacaggt tcctgacaat ttctttcttt tcgtgtataa tagtggaaaa
    11641 gagctaaaac gaggtatggt tatggaagga gttctttact caacattccg aaatcattta
    11701 aaggattaca tgaagaaggt aaatgatgaa tttgagcctt tgacggtggt caataaaaat
    11761 ccagatgagg acattgtagt tctttcaaag agcgaatggg acagtattca ggaaaccctg
    11821 agaatcgccc aaaataagga gttatcagac aaggttttgc gaggaatgga taaaattcgc
    11881 gcaggacact agtctaattt acagagaata cctgagtgaa atcttgctgt tgttagaaac
    11941 aaacttcttg tattgcataa tcattaggaa gtctactgca aagtaggctt tttctcaagt
    12001 ctctactaaa ctactatttc taaacaacaa gtttattttg gtaaatgtgt tccaaattcc
    12061 ccaaaacata ttctatttta ggtttgtgaa aatcactttt ttatggtaga atgtaaaaga
    12121 atgtatgtca ttcggaataa caataaaatg aggtaaaaac atggaaatca tgtcgcttgc
    12181 gattgctgtt tttgccgtca tcattggttt agtcattgga tatgtcagca tctcagctaa
    12241 gatgaaatca tctcaggaag ctgcagagtt gatgctttta aatgctgaac aagaagcaac
    12301 taatttacgt ggacaagctg agcgtgaagc ggatttactt gttaatgaag ccaaacgtga
    12361 aagcaagtct cttaaaaaag aagcactatt ggaggccaaa gaagaagcca gaaaataccg
    12421 tgaagaagtg gacgctgaat tcaaatcaga acgtcaagaa ctcaaacaaa tcgaaagtcg
    12481 tttgacagag agagctacta gccttgaccg taaggacgac aatttgacga gtaaagaaca
    12541 aacacttgaa caaaaagaac aaagtatttc tgatagagcg aaaaaccttg atgcgcgtga
    12601 agagcaatta gaggaagtcg aaagacaaaa agaagcagaa ctagagcgta ttggtgctct
    12661 gtctcaggca gaagcacgag atattatctt ggctcagaca gaggaaaact tgaccaggga
    12721 gattgccagt cgcattcgcg aagctgagca agaggtcaag gaacgttctg acaaaatggc
    12781 caaggacatc ttggttcaag ctatgcaacg tatcgctggt gaatatgtag cggagtcaac
    12841 aaactcaaca gttcatctgc cagacgatac tatgaaggga cgcattattg gtcgtgaagg
    12901 tcgtaacatt cgtacctttg aaagtttgac aggggtcgat gtgattatcg acgatacacc
    12961 agaagtggtg accttgtcag gatttgatcc gattcgtcgt gagattgccc gtatgactat
    13021 ggaaatgttg ctcaaagatg gtcgtataca tccagctcgt atcgaagagt tggttgagaa
    13081 aaaccgtcaa gagattgaca ataagattcg tgaatacggt gaggctgctg cctatgaaat
    13141 tggtgcgcca aaccttcatc cagacttgat gaagattatg ggacgtttgc agttccgtac
    13201 ttcatatgga caaaatgttt tgcgccattc gattgaggtt gctaagttgg ctggtatcat
    13261 ggcgagcgaa cttggtgaaa atgcggctct tgcccgtcgt gctggattcc ttcacgatat
    13321 cgggaaagcc attgaccatg aggttgaagg tagccacgtt gaaatcggta tggaattggc
    13381 ccgtaagtac aaggaacccc cagttgtggt gaatacgatt gctagtcacc acggagatgt
    13441 tgaagctgag agcgtgatag cagttatcgt cgctgcagca gatgccttga gcgcagcccg
    13501 tccaggtgct cgtagtgagt ctcttgaaag ctacatcaag cgtctccatg atttggaaga
    13561 aattgctaac ggctttgaag gagtgcaaac tagctttgcc cttcaagcag gacgtgaaat
    13621 tcgtatcatg gtcaatccag gaaaaatcaa ggacgacaaa gtcacaatct tggctcacaa
    13681 agttcgtaag aaaattgaaa acaatctcga ttatccagga aatatcaagg taaccgtgat
    13741 tcgcgagctt cgtgcagtag attatgctaa ataa
//
LOCUS       DAVHKZ010000049        12598 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000049 DAVHKZ010000000
VERSION     DAVHKZ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12598
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.049"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..399
                     /locus_tag="VVO74_001901"
     CDS             <1..399
                     /locus_tag="VVO74_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU5695884.1"
                     /translation="KVSGRRYQRISLVAGLTNGELIAPMTYEEMMTSDFFEAWFQKFF
                     LPTLTTPSVIIMDNVRFHRMGKNVRFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEK
                     TWAHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            complement(601..2859)
                     /locus_tag="VVO74_001902"
     CDS             complement(601..2859)
                     /locus_tag="VVO74_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU5695885.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(3088..3318)
                     /locus_tag="VVO74_001903"
     CDS             complement(3088..3318)
                     /locus_tag="VVO74_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEU5695886.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3508..4191
                     /locus_tag="VVO74_001904"
     CDS             3508..4191
                     /locus_tag="VVO74_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU5695887.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            4191..4925
                     /locus_tag="VVO74_001905"
     CDS             4191..4925
                     /locus_tag="VVO74_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU5695888.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            5079..5936
                     /locus_tag="VVO74_001906"
     CDS             5079..5936
                     /locus_tag="VVO74_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU5695889.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETGLVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAMDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            6078..6950
                     /locus_tag="VVO74_001907"
     CDS             6078..6950
                     /locus_tag="VVO74_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU5695890.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            7232..7915
                     /gene="rpiA"
                     /locus_tag="VVO74_001908"
     CDS             7232..7915
                     /gene="rpiA"
                     /locus_tag="VVO74_001908"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU5695891.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7929..9140
                     /locus_tag="VVO74_001909"
     CDS             7929..9140
                     /locus_tag="VVO74_001909"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU5695892.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            9142..9684
                     /locus_tag="VVO74_001910"
     CDS             9142..9684
                     /locus_tag="VVO74_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEU5695893.1"
                     /translation="MTRYSLLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9700..10509
                     /locus_tag="VVO74_001911"
     CDS             9700..10509
                     /locus_tag="VVO74_001911"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU5695894.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGGFKGLLKAILAEL"
     gene            10985..11380
                     /locus_tag="VVO74_001912"
     CDS             10985..11380
                     /locus_tag="VVO74_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEU5695895.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            11390..11965
                     /locus_tag="VVO74_001913"
     CDS             11390..11965
                     /locus_tag="VVO74_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU5695896.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            12037..12501
                     /locus_tag="VVO74_001914"
     CDS             12037..12501
                     /locus_tag="VVO74_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU5695897.1"
                     /translation="MELEGYNALSLAEVEVFRFIATNAETATQVSKPVQPISQTPVKD
                     KTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGCNQTAGFVLNLPIKENM
                     RNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTLNSKVSDDDVL"
BASE COUNT         3727 a         2304 c         2845 g         3722 t
ORIGIN      
        1 aaagtatctg gaagaagata tcagaggatt tctttggttg caggtctaac aaatggtgag
       61 ttaatcgctc caatgactta cgaagagatg atgacgagcg acttttttga agcttggttt
      121 cagaagtttt tcttaccaac attaaccaca ccatcggtta ttattatgga taatgtaaga
      181 ttccatagaa tggggaagaa tgtaagattc catagaatgg ggaagctaga acttttatgc
      241 gaagagtttg ggcataaact tttacctctt cctccctact cgcctgagta caatcctatt
      301 gagaaaacat gggctcatat caaaaagcac ctcaaaaagg tattaccaag ttgcaatacc
      361 ttttacgagg ctcttttgtc ctgttcttgt ttcaattgac tatagcagat tgaaatgaga
      421 acaaatcgat tgggaaagta aaattaattt ctataaatgt tttagcaatt gtttcgtact
      481 atttcagatt cagtctacta tatatcataa tggacaaagg gcaagctgtc aagaaattac
      541 agttatttta gtaaaaaaag aagcagaaaa atttcatttt ctactccttt tctataggat
      601 ttatttttct ttttcagaac ttttaacttc agcttttttg gcagatttaa tctgaatgtt
      661 tcccttgcta gtcataactg ctttgagatc tttttcgctt ggattttcaa ggtagtagtc
      721 agtgattgtg tcctcaatat agtcttgaat agtccgacga agtgggcgtg ctcccatttt
      781 tggatcataa cctaggtcaa ccaacttttc cttgacctta tcagttacat ccaaacgaat
      841 gttgttgcta gagaggcgct tgttaacatc tgctagcatg agctcgacaa tctgaaggag
      901 gttatccttg ctgagagcct taaattcgat aatgccatca aaacggttca taaactctgg
      961 gctaaagaag ttaccgagtt caccgaggac agaattggta cgtccttctc tagcagcacc
     1021 aaatccaacg ctagcttcgg tctttcctgt acctgcattt gaggtcatga taatgatggc
     1081 atccttgaag ctaacggtgc gtccttgccc gtctgtcaaa cgaccatcgt ccaagacttg
     1141 aagaaacatg tgcataacat ctgggtgagc tttttccact tcatcgagaa ggatgagaga
     1201 atatggattg tggcgaactt tttcagttaa ttgaccagcc tcatcatagc caacataacc
     1261 tggaggggcg ccgaccaact tagccacact atgtttttcc atgtattcac tcatatcaaa
     1321 gcgaatcata ctatcagcag aaccaaaaag ttcgatagcc agttgtttgg aaagttctgt
     1381 cttaccgaca ccagttggcc caacgaagag gaagcttccg attgggcggt taggggtacc
     1441 aagtccgaca cgattacggc gaatagcctt ggcaatctta tcgactgcat catcttggcc
     1501 aataacatga gacttgagat cttcggctag atggatgagt tgagattgtt ctttctcttt
     1561 caaatcacca acagggatat tggttttctg ctcgataatg tgctcaatag ttttctcgct
     1621 gatgatagga gtatcctggt ctgtgatctt tttcttttgc atttccttat acttggcaat
     1681 ctggtcgcgg aagtaggccg ccttctcaaa atcttcttct cgtgtagctt gagacttgag
     1741 attttcagcc tcaatcaagc gctgatcaat tactttagga tccacaaaat tcaaggtcaa
     1801 gttcatctta gaaccagctt catctaggag gtcaatggcc ttgtcaggca agaagcgatc
     1861 ttggatgtag cgattggaaa gagttgcagc tgcttcaatc gcagcatcgg tatattgaac
     1921 gtggtggtaa tcttcgtatt tcttttgaat ccctttgaga atagtgattg tttcgtccac
     1981 cgttggttca tcgactttaa caggctgcat acgacgctcg agggcagcat ccttttcaat
     2041 gatacggtat tcattgaggg tagtagcacc gactagttgc agttctccac gagcaagggc
     2101 tggcttgagg atatttcctg cgtccatatt accatcactc gcagaaccag caccaacaat
     2161 ttcatggatt tcatcgataa agaggatgat gtcttcacgt ttgcgaattt cttccatgag
     2221 tttttgcatg cgttcttcaa attgtcctcg aatccccgtt ccttgaacta agctaaccac
     2281 atccagacgg atgacttgtt taccttggag tttatgtggc acatcgccat cgacaatttt
     2341 ctgagctaga ccttcgacaa cggccgtttt tccgacacca ggttcaccga taaggacagg
     2401 attattcttg gttctacgat tgagaatctc gatgacacgg ataatctcat cgtcgcgccc
     2461 aataacgggg tcaatgtctc cacgacgggc aatttcagtt acattaatac caaattcttc
     2521 cagcaggcct ttttcttggc taggtggcgg agtttgagca gatccacgat tttgggaacc
     2581 ataaccgccg tttccaccgt aacctccacc tgattgggtt gggggaatag gaggagtatt
     2641 gctagaaggt ctgaaattgt ttagatcatt gaagaaatca ccaaagggat cgaagtcacg
     2701 attgttcaga tccgtcatac ctttgaagag gctattgtta ggatctgttt tgataatctt
     2761 atagcagttt tgacagaggt caatttgttt ttgttttcca ttgagattgg tgtaaagatg
     2821 aattgttgag tcgttaattt tacagttttg acaaagcata catctacctc atttctttct
     2881 ttagcctgac ttgtttaaag gtcaaaaata gtcaaattct atactctcat tataacagga
     2941 ttggggtgta aagcaagtaa aaagattgaa gctttgagaa gttgttacaa tgaaaatttt
     3001 tgtgaatttg gactataaaa aaatcctatt tgtgagacaa aaaggatttt acttagacat
     3061 gcagggacaa tcccagcttg ttttagatta gtagagaagt tcgtaaattt ccattgcgat
     3121 taagtcaatg ctatcaaacg tatacgtttc gcgatcttct acgtcacgaa gggtaaagat
     3181 tgggccgttt tcttcgtcgt ggctgtacgc aacttctgca acaacaactc cttcgcgttc
     3241 aaaattacgt tttaaatttc cgccatcgtt tgccattgct tcaaggcggt tgatgattct
     3301 aaccaaatgt gattccattt tgattctcct tcatttctta tcgttactat tttaccataa
     3361 aggaggccaa cttgactaga aaaaactaag atttctcact aattctgcta gtttaaagat
     3421 ttttaaataa attggataaa agatttaaat tttaattcaa aacatgttat aatcatacag
     3481 tattctattt tagaaagcag tgtgactatg aatttttctt ttttacctaa gtatttacct
     3541 tattttaact atggggctgt tgtgacgatt cttatttcta tctgtgttat ctttttggga
     3601 actattttgg gtgttgtctt ggcttttggg caacgttcaa agtttaaacc gcttgtttgg
     3661 ttggccaact tgtacgtttg gattttccgt gggacaccga tgatggttca aattatgatt
     3721 gcctttgctc ttatgcatat caatgctccg actattcaga ttggaatttt aggtgttgat
     3781 ttttcgcgtc tgattccagg gattttgatt atctctatga atagtggtgc ttatgtttcg
     3841 gagactgttc gtgccggaat caatgcggtt ccaaaaggtc agctagaggc ggcttattcg
     3901 ctagggattc gtcctaaaaa tgcgatgcgt tatgtgattt tgccacaagc agtcaaaaat
     3961 atcttgccag cattggggaa cgaatttatc accattatca aggacagctc cctcttatca
     4021 gctattgggg tcatggagtt gtggaatggg gctacaacag tttctacaac aacctatcta
     4081 cctttaacac cacttttatt tgcagcattt tactacttga ttatgacctc tattctgaca
     4141 gtagccttga aagcttttga aaaacatatg ggacaaggag ataagaaata atgacagaaa
     4201 ccttgataaa aattgaaaat ttacataaat cttttggaaa gaatgaagta ttgaagggca
     4261 tcaacctcga gattaaaaga ggagaagttg tcgttatcat cggtccttca gggagtggga
     4321 aatctacctt gcttcgctct atgaatttgt tggaggaagc aaccaagggg aagcttatct
     4381 ttgagggagt cgatattacg gacaagaaga atgacctgtt tgccatgcgt gagaagatgg
     4441 gcatggtttt ccaacaattt aacctctttc ctaatatgac tgtgatggaa aatattacct
     4501 tgtcacctat caagactaaa ggtgaaagca gggaagttgc tgagaagaga gcccaagagc
     4561 ttttggaaaa agttggtttg ccagataagg cagacgctta tccacagagt ctgtcgggtg
     4621 ggcaacaaca acggattgcc atcgcgcgtg ggttggctat ggaaccagat gttttgctct
     4681 ttgacgaacc aacttcagcc ttggatcctg aaatggtagg tgaggtattg gctgttatgc
     4741 aagaccttgc caagtcaggg atgactatgg ttatcgtaac acatgagatg ggatttgccc
     4801 gtgaggtggc agatcgtgtt atctttatgg cagacggtgt ggttgttgaa gatgggacac
     4861 ctgagcagat ttttgaacaa acccaagaac aacggactaa agatttcttg agtaaggttt
     4921 tataatctat tttaaaattt caagacaaga ttagtgaaaa gttcaaccag agctttttct
     4981 tatagtttga aactatagga taacctagga aagaagtgtt agagggcact agcagttttt
     5041 ggtataatgg aagatatttg aaagaaaaga gaagtgatat gacacagatt attgatggga
     5101 aagctttagc ggccaaattg caggggcagt tggctgaaaa gactgcaaaa ttaaaggaag
     5161 aaacaggtct agtgcctggt ttggtagtga ttttggttgg ggataatcca gccagccaag
     5221 tctacgttcg caacaaggag aggtcagctc ttgcggctgg ttcccgtagc gaagtagtgc
     5281 gagttccaga gaccattact caagaggaat tgttagacct gattgctaaa tataatcagg
     5341 atccagcttg gcatgggatt ttggtccagt tgccattacc aaaacatatc gatgaagagg
     5401 cggttttatt agccatggat ccagaaaagg atgtggatgg tttccatccc ctaaacatgg
     5461 gacgtctttg gtctggacat ccagtcatga ttccctcgac acctgcagga attatggaaa
     5521 tgtttcatga atatgggatt gacttggaag gtaaaaatgc ggtcgtcatc ggtcgttcaa
     5581 atatcgttgg aaaacctatg gctcagcttc ttttggctaa aaatgcgaca gtaaccttgg
     5641 cccactcacg aactcataat cttgccaagg tggctgctaa agcagatatt cttgtagtcg
     5701 caatcggccg cgccaagttt gtgactgctg actttgtcaa accaggtgcg gttgtcattg
     5761 acgttgggat gaatcgagat gaaaatggga agctctgtgg agatgttgat tatgaggcag
     5821 ttgcaccact tgctagccat atcacgccag tccctggagg tgtcggtcct atgaccatta
     5881 ccatgctgat ggagcaaact tatcaagcag cacttcggac attggataga aaataagaga
     5941 aacattcgat taatagagtg tattttctat agctatatct aaaatggcag aaatgaatat
     6001 taaattttag atataagatt acaaaaggag gtctgcgtct cctttttatt gtataataaa
     6061 agtgagagga aaaaaggatg aaagtgatta atcaaacctt attagaaaaa gttattattg
     6121 aacgttctcg ttcaagtcat aaaggagatt atggtcgtct gctgctgctt ggtggtactt
     6181 atccttatgg aggtgccatc atcatggctg ctttagcagc tgtaaaaagc ggtgcaggat
     6241 tggtgaccgt tggaacggac agggaaaata tcccggctct gcacagccat ttacctgagc
     6301 ctatggcctt ttctcttcaa gaccagcaat tgttaaaaga gcaattggag aaggcagaag
     6361 ttgtcttgct ggggcctggt ttacgagacg atgcttctgg agaaaatcta gtaaaacagg
     6421 tctttgttaa tttaagccaa aatcagattt tgattgtaga cggaggtgcc ttgaccattc
     6481 ttgctaggac aagtttgtca tttccctcaa gccagcttat cctaactcct caccaaaaag
     6541 aatgggaaaa attatctgga attacgattg aaaagcaaaa ggaagatgca acggctagtg
     6601 ttctgacttc cttccctcaa ggaacaattt tggtggagaa aggcccagct actcgtattt
     6661 gggaagttgg ccaatctgat tattaccagt tacaggttgg tggtccttat caggcgactg
     6721 ggggaatggg agatactctg gctgggatga tcgcaggatt tgtaggccaa ttccgacagg
     6781 ccagtctcta cgagcgtgtg gcagtagcga cccatcttca ttcagccata gcccaagaac
     6841 tatctcaaga aaattatgtg gtcttaccga cggaaatcag caggtatctt cccaaaataa
     6901 tgaaaattat ttgtcaacaa gagagggtaa gtaaagataa acttgtttaa aatagacaga
     6961 taaatctact tccttctctt aatttatgat tcttgaaatg cgcctgcttt aaggctaaac
     7021 tagacgtatc aaagttaaga ttttgttttt gtaactggaa agagatgaac aaatcaaata
     7081 cataaaagat aaactcattt ttattcgttt ggtaaaaata aaatgcatat ttttaaagaa
     7141 agattgatga aaaatgtaga tttgatgttt ttacttgaat aaaaagcggt ttcatagtaa
     7201 aataagaact gagaatgatg gaggtaaatc ggtggaaaat ctgaagaaaa tggcaggtat
     7261 caaggctgct gagttcgtga gcgatggaat ggtcgttgga cttggaacag gctcgactgc
     7321 ctattatttt gtcgaagaaa tcggtcgtcg tatcaaggaa gaaggattgc agattacagc
     7381 tgtaacaact tctagtgtga ccactaaaca ggcagaaggc cttaatatcc cgctcaagtc
     7441 tattgaccaa gtagactttg tcgatgtgac ggttgatggc gcggatgaag tggatagtca
     7501 gtttaatgga atcaaaggcg gtggtggtgc ccttctcatg gaaaaggtgg tcgcaacacc
     7561 atcaaaagaa tacatttggg tggtggatga aagcaagctg gtcgaaaaac taggtgcttt
     7621 taaattgcca gtagaagtgg ttcagtatgg tgcagagcag gtctttcgtc attttgaacg
     7681 agctggctac aaaccaagtt tccgtgaaaa agacggccaa cgttttgtga cggatatgca
     7741 gaattttatc attgacctcg ccttggatgt cattgaaaat ccaattgctt ttggacaaga
     7801 attggaccat gtcgttggtg ttgtggagca tggtttattc aaccaaatgg tggataaggt
     7861 aatcgttgct ggacgagatg gagttcagat ttcaacttca aaaaaaggaa aatagaaggg
     7921 ggcataagat gtctaaattt aatcgtattc atttggtggt actggattct gtaggaatcg
     7981 gtgcagcacc agatgctaat aactttgtca atgcaggggt tccagatgga gcttctgaca
     8041 cactgggaca catttcaaaa acagttggtt tgaatgtccc aaacatggct aaaataggtc
     8101 ttggaaatat tcctcgtgaa actcctctta agactgtagc agctgaaagc aatccaactg
     8161 gatatgcaac aaaattagag gaagtatctc ttggtaagga tactatgact ggacactggg
     8221 aaatcatggg actcaacatt actgagcctt tcgatacttt ctggaacgga ttcccagaag
     8281 aaatcctgac aaaaatcgaa gaattctcag gacgcaaggt tattcgtgaa gccaacaaac
     8341 cttattcagg aacggctgtt atcgatgatt ttggaccacg tcagatggaa actggagagt
     8401 tgattatcta tacttcagct gaccctgttt tgcagattgc tgcccacgaa gacattattc
     8461 ctttggatga attgtaccgt atctgtgaat acgctcgttc gattaccctt gagcgtcctg
     8521 cccttcttgg tcgcatcatt gctcgccctt atgtaggtga accaggtaac ttcactcgta
     8581 cggcaaaccg tcgtgacttg gctgtatctc cattttcccc aactgttttg gataaattga
     8641 atgaggctgg tatcgatact tatgctgtgg gtaaaatcaa cgatatcttt aacggtgctg
     8701 gtatcaacca tgacatgggt cacaacaagt caaatagtca tggaattgat acactattga
     8761 agactatggg acttgctgag tttgaaaaag gattctcatt cacaaaccta gttgactttg
     8821 atgcccttta cggccatcgt cgtaatgctc acggttaccg tgattgcttg catgagtttg
     8881 atgaacgctt acctgaaatt atcgcagcta tgagagagaa tgaccttctc ttgattactg
     8941 cggaccatgg aaatgaccca acgtatgcag gaacggatca cactcgggaa tatattccat
     9001 tgttggccta tagccctgcc tttaaaggaa atggtctcat tccagtagga cattttgcag
     9061 atatttcagc gactgttgcc gataactttg gtgtggaaac tgctatgatt ggggaaagtt
     9121 tcttagataa attggtataa gatgacgcgc tattctttgc tggtgagagg tatcaatgtt
     9181 ggtggtaaga ataaggtcgt catggcggag cttcgtcaag aattgacaaa cttgggactg
     9241 gaaaaggttg agagctacat caacagtggc aatattttct ttacttcgat agattccaaa
     9301 gcccaattgg ttgaaaagct agagactttc tttgcagtcc attatccatt tattcagagc
     9361 ttttctttac tgagcctaga ggactttgag gcggaacttg aaaatctacc agcttggtgg
     9421 agcagagact tggcacgaaa agattttctc ttttacactg agggtttgga tgtggaccaa
     9481 gtcatcgcga cagttgaaag tttagagctg aaagatgaag tgctttattt tggaaaactt
     9541 gggattttct gggggaaatt ttctgaagaa tcctattcta agactgccta tcataagtac
     9601 ttgctgaagg tgcctttcta ccgccacatt actattcgta atgctaaaac ctttgacaaa
     9661 attggtcaaa tgctaaaaaa ataataaagg agacacacaa tgacattttt aaacaaaatc
     9721 catgaaactg ctactttcct gaaagaaaag ggaattgcag cccctgagtt cggtctaatc
     9781 cttggatcag gacttggaga attggcagaa gaaatcgaaa atccagttgt agtagactat
     9841 gctgagattc caaactgggg ccgttcaaca gtagtcggtc atgctggtaa attggtatat
     9901 ggtgaactgg caggtcgcaa ggtcttggct cttcaagggc gtttccattt ctatgaaggg
     9961 aatcctctgg aagtggtgac tttcccagtt cgtgtgatga aagttcttgg atgtgaaggt
    10021 gttattgtaa ccaatgcagc tggcggtatc ggatttggtc ctggtacctt gatggctatc
    10081 tcagaccata tcaacatgac ggggcaaaat ccattgatgg gtgaaaactt ggatgacttt
    10141 ggcccacgtt tcccagatat gtctagggct tacacaccag aataccgtgc cactgcccat
    10201 gaagtggcta aaaaacttaa tatcaagctt gatgaaggtg tctatatcgg agttactggt
    10261 ccgacttatg aaacaccagc agaaattcgt tcctataaga cactgggagc agatgcagtt
    10321 ggtatgtcta cggttcctga agttatcgtg gcagcccact ctggcttgaa agttctggga
    10381 atttcatgta tcactaactt tgcggccggt ttccaagaag aactcaatca cgaagaagtt
    10441 gtagaagtga ctgaacgtgt taaaggtggt ttcaaaggct tgcttaaagc gattcttgct
    10501 gaattgtaag aaaaaagatt taaaaggggg agtgcctctg tcttttcagg attgactgcc
    10561 tatccgtatt aaagaagaaa cagaggaata ctatgagctt cttcctgctc ttataactga
    10621 aagaagcgga agaataggta tgtctgatct gatagccagc attgtgaaag acaagattct
    10681 aggatactag cattagcttc ctagccaagc agactagtat gataaggaga gatgagaatg
    10741 aattgacttt ctgaatttct cagtcttatc atatatagca caatgagatt tcgcttgagt
    10801 ctgcttgtaa ataaacgaaa agaaagataa gaaataatga aaattggtca acgaattatg
    10861 cgctttggca taaaaaatta agtatcggag ttgtatctgt tgtagtcggc tttgatttct
    10921 agctccagct ggaatttcag ccaatgaagt aaagcaagat gtaacatctg aagtggtaat
    10981 aggtgtgcta gattctaagg aggaattgaa agagtcagaa aatgatgctc caaaactaga
    11041 aactcctctt agagaggagc caagactagc tcctcaaacg cttccggaag caagtgaagt
    11101 tcttgaaaac aaaagggaag agtcaaaagt agagataaca gagccagctc aagcggatga
    11161 tatccgcaag gttgttgggg aattagccaa ggatataagt attactaagt tgtatatgac
    11221 aggtcattct cttggaggct acctagctca gattgcagcg gttgaagatt accaaaaata
    11281 tcctgatttt tataaccatg tattgaggaa agtgacaact ttcagtgctc ctaaagtgat
    11341 tacttccaga actgtttggg atgctaagaa tggtttctga gatgttggtt tggaaagtcg
    11401 taaattagct gttagtggaa aaattaagca ttatgtggtt gataatgaca atgttgtgac
    11461 tcccttgatt cataataatc gtgatattgt tacatttaca ggtaattcac gctttaaaca
    11521 ccgttctcgt ggctattttg aaagtccaat gaatgatatt cctaacttta atattggtaa
    11581 acaagctacc ttggataaac atggttatcg tgatccgaaa ttggataaag tgcgattctt
    11641 taagaaacag gctctacctc aatcttctag tcaaccaagc gctgaaccaa tggaaaatat
    11701 tgccttagga aaacaggtta ctcaaagttc gacagctttc ggaggagatg ctagaagagc
    11761 tgtggatggc aaagtcgatg gtaactatgg tcacaattct gtcactcata caaacttcca
    11821 atctaagcct tggtggcaag tagatttggc taaagaagaa accattcgcc aaatcaatat
    11881 ttacaaccga acagacactg cccaggatag attggcaaac tttgatgtca ttcttttaga
    11941 cagttctggt aaagaaattg agtgaaaacg tataatatct cctaaagatg tgtcagcaca
    12001 aattacgatt aaccataaaa aacgcgctat gttcggattg agctagaagg ctataatgcc
    12061 ctcagtcttg cagaagttga agttttccgc tttatagcta cgaatgctga aacggcgaca
    12121 caagtttcta agccagttca accaatcagt cagactcctg tgaaagataa aacattgaca
    12181 attcaacaca gtggagctta cattgcccgc tactccataa cttgggaaga agttccagta
    12241 gataaagatg gaaaccaagt tgttcgtagt cattcttggg aaggaaacgg ttgcaaccag
    12301 actgcaggtt ttgtcctcaa cctcccaatc aaagaaaata tgagaaatct gcgagttaag
    12361 attgagaaaa agacgggcct actatggaat agatggcaaa caatctatga aaacagacca
    12421 attttagctc aaccccaccg taaaattacc cattggggta cgacattgaa ttccaaggtg
    12481 agtgacgatg atgtcttgta atctgatggt acaatgacag ttagtttgtc tagtttataa
    12541 gaaagtacta cctgagcttg aatagaactc aggtagctct ctgtgaaaga acaaaatt
//
LOCUS       DAVHKZ010000050        12498 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000050 DAVHKZ010000000
VERSION     DAVHKZ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.050"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            192..752
                     /locus_tag="VVO74_001915"
     CDS             192..752
                     /locus_tag="VVO74_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU5695898.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            753..2138
                     /locus_tag="VVO74_001916"
     CDS             753..2138
                     /locus_tag="VVO74_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695899.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVAASPELFHMNRVTGELGNRSLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            2140..2790
                     /locus_tag="VVO74_001917"
     CDS             2140..2790
                     /locus_tag="VVO74_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU5695900.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFLPSIALNLLVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            2801..3559
                     /gene="tenA"
                     /locus_tag="VVO74_001918"
     CDS             2801..3559
                     /gene="tenA"
                     /locus_tag="VVO74_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU5695901.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEEWKHEKAPTTSSQINHFIYDDCP"
     gene            3498..4022
                     /gene="thiW"
                     /locus_tag="VVO74_001919"
     CDS             3498..4022
                     /gene="thiW"
                     /locus_tag="VVO74_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU5695902.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            4022..4825
                     /locus_tag="VVO74_001920"
     CDS             4022..4825
                     /locus_tag="VVO74_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU5695903.1"
                     /translation="MQEFTNPFPIGSSSLIHCITNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            4818..5450
                     /locus_tag="VVO74_001921"
     CDS             4818..5450
                     /locus_tag="VVO74_001921"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU5695904.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKIETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(5659..6450)
                     /gene="thiD"
                     /locus_tag="VVO74_001922"
     CDS             complement(5659..6450)
                     /gene="thiD"
                     /locus_tag="VVO74_001922"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU5695905.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(6534..6632)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6816..7211
                     /locus_tag="VVO74_001923"
     CDS             6816..7211
                     /locus_tag="VVO74_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU5695906.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVDKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            7222..7593
                     /locus_tag="VVO74_001924"
     CDS             7222..7593
                     /locus_tag="VVO74_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU5695907.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKRSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            7603..9846
                     /locus_tag="VVO74_001925"
     CDS             7603..9846
                     /locus_tag="VVO74_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU5695908.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKEIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNILGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            10053..11828
                     /gene="spxB"
                     /locus_tag="VVO74_001926"
     CDS             10053..11828
                     /gene="spxB"
                     /locus_tag="VVO74_001926"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU5695909.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            11939..12286
                     /locus_tag="VVO74_001927"
     CDS             11939..12286
                     /locus_tag="VVO74_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU5695910.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
BASE COUNT         3558 a         2405 c         2778 g         3757 t
ORIGIN      
        1 tcttttacga aactggatga agatgatata gtagattgaa ataagatgcg aacaaatcaa
       61 ttagaaaatt caaattaatt tctagaaata ttttagcatt cttgtgtact gttctaaatt
      121 cagtctgcta tacaaagtat ttaggtcggt cttcttgagt gccccacttt tctttaaaaa
      181 aaggagtttt tatgttgaaa aaatggcagt taaaagatgt tatcttgctt gctttcttgt
      241 ctatcttttt tggtggggtt ttcgttggtt caggatatgt gtataatatt ctcagtctac
      301 tcttaacacc tcttggtttg caggcctttg ccaatgaaat cctcttcggt ctctggtgta
      361 tggctgcgcc cattgctgcc atctttgttc caagagtcgg aagtgcaacg attggagaag
      421 tgctagctgc gcttgctgaa gtcctttatg gtagccaatt tggtctagga gctcttttgt
      481 ctggcttggt tcaaggtttg ggaagtgaat ttggttttat cgtaactaag aatcgctatg
      541 aaagttggct ctctctaact gctaatagta ttgggattac gcttgttagc tttgtctatg
      601 aatacattaa gttaggttac tacgcctttt cccttccgtt tgtcctttcc ttacttgtgg
      661 tacgttttat ttctgtttat ttcttctgta ccatcttggt tcgtgccatt gtcaaactct
      721 atcatcagtt tgcaactgga ggaaaagcat agatgggtct ggaactacga gcgattcagt
      781 ccccaatctt ctctgagccg tttgatttta cttttcatgc gcaagccttt accttgttag
      841 ttgggagcag tggttcagga aaatccagcc tttttcaagt cattgcccaa gtcagttctc
      901 ttccctatag tggtcaagtc ctgatagatg ggagcgaggt cagtcagctt tctatcatcg
      961 cacgtgtcca gaaggttggc attctcttgc aaaatcccaa tcatcaattt accatggaga
     1021 acttgtttga ggagttgatt ttcaccttgg agaatatcgg ctatcacctt caggaaattg
     1081 attctaaaat agcagaggtt gtccagcaat gtcgttgcga ggcaatctta caccgtccca
     1141 ttcatcacct atcaggtggg gaaaagcaaa aagcagcgct ggctgtcctc tttgccatga
     1201 atcctagggt ctatctcttg gatgagccct tcgcttccat tgaccgcaag agtagaatcg
     1261 agatattgga gattctaaaa gagttggctc ttgatgggaa gacagtcatt ttgtgcgacc
     1321 atgatttatc tgactataaa gcctatatcg accatatggt tgagctaaga gacggaaaac
     1381 taagggaagt gtttcaaatc ccttcctatg agatgacaca ggttgcttca aaggaagttg
     1441 ctgctagccc ggaattattc catatgaacc gtgtgactgg tgagcttgga aatcgctccc
     1501 tcttttcgat tgctgatttc acattctatc aagggatttc ctgtatcctg ggtgacaatg
     1561 gtgtcgggaa atcaaccctc tttcgctcta ttcttcaatt tcaaaagtat aaggggcgca
     1621 ttacttggaa gggttcggtc ctgaaaaaga aaaagagttt gtatcgtgat ctgactggtg
     1681 ttgttcagga agctgagaag cagtttatcc gagtcagtct gcgagaggag cttcaattag
     1741 atggacctga ttctgaaaga aatcagcgga tttttcaagc tttacgatat tttgatttgg
     1801 agcaggcagt cgataagagt ccctatcaat taagtggtgg tcagcaaaaa attcttcagc
     1861 tcttgaccat cttgaccagt aaggcttccg tgatcttgct agatgaacct tttgcaggtt
     1921 tggatgatag agcctgccat tatttttgca agtggattgt ggaggagagg aatcaaggaa
     1981 gaagttttct gctcattagt catcgtttag accctttgat ttctgtggtt gattattgga
     2041 ttgagatgac tagtcagggt cttcggcatg tgaaagaagt gaccattacc aaaccactta
     2101 catctcagag tagcaatacc caaggggagg tgagatagta tggtcaaagt agcaacccag
     2161 acaccgatta tcagtctctt cttgctgatt ttatccttgg aaacatcttt ccttccttcg
     2221 attgctctga atcttttggt agtcgcattt tgtattctct ttatgctcta ttaccgtcga
     2281 tttaaaatgt tagcttggat gatcatactt gccattttac catcttttgc caactactgg
     2341 gcagttcagt tacacggaga tgcttcacag gcagtcatgc ttggaacgag ggcctttgtg
     2401 acagtttgta tcggccttgt ctttgtttcc tctatttcac taaaagagct tctcttgtac
     2461 ttggctcaaa aggggctatc acgctcttgg tcctatgcct tgattgtggt attcaattct
     2521 tttcctctca ttcagcaaga aatcaagtcc ctcaaagaag cttgcctatt acgtggtcaa
     2581 gaactacatt tttggtcgcc cttgatttac agtaaggttc tgatgacagt ctttaggtgg
     2641 cgccatcttt acctgagagc tctatctgct cacggatatg acgaacatgc acagttgaag
     2701 aatagctatc ggacttttta tattcctaaa aaaacaaaat taatctacct gcttttcttt
     2761 ttattgcttc aaaccagtct atttttataa aggagttatt atggaattta cagatattgc
     2821 gatggaatta tccaagaaag cttggcaggc ttcctttcat catcccttta ttttacaatt
     2881 acaagagggg aatttagaac ctgccatttt ccgctattac ctgattcagg atgcctacta
     2941 tctgaaggcc ttctcagaaa tctatcatct tttggctgat aagacttcaa accaagagat
     3001 gaaaagactc ttgaaacaaa atgctcaggg tttagtggag ggtgagttat ttattcgcca
     3061 acaatttttc aaggaaatgg aaatcagcga ccaggaaatg gagcaacatc caatcgctcc
     3121 aacctgttat cattacattt ctcatattta taggcaattt gcagaaccga acttagccat
     3181 cgcttttgca agcttgcttc cttgtccttg gttataccat gatataggca aatcacttaa
     3241 tcttaaacca tcaccaaatc ctctctatca acaatggatt gaaacttata ttacggatga
     3301 gttagagcaa cagatcagag aggagggagc actggtcaat cagctctatc gagaaagtga
     3361 cgagacagac aagcaaaaaa tgctagatgc cttccacatc agtgttcata tggaagccaa
     3421 gttttgggaa atggcctacc aacaccagac atggaagagc gatttacagt ctttagaaaa
     3481 aggagaagaa tggaagcatg agaaagcacc aactacaagt tcacaaatta accattttat
     3541 ctatgatgat tgcccttgat gtagtcctta cacctatctt tcggattgag ggaatggcac
     3601 cgatgtccag tgtagtcaat attctagcgg gaatcatgat gggacctgtt tatgccttgg
     3661 ctatggctac agtgacagcc tttatccgta tgacgactca agggattccg cctttagctc
     3721 tcacaggagc gacttttgga gcccttctag caggtctctt ttataagtac ggtcgaaaat
     3781 tttacttttc tgccttggga gaaattgtgg gaacaggtat tattggttct attgtttcct
     3841 atcctgttat ggtactcttt acaggatcag ctgctaagct tagctggttt atctacacgc
     3901 ctcgattttt cggagcaacc ttgattggta cagcgatttc ctttattgcc tttcgatttt
     3961 taatcaagca ggaattcttt aaaaaagtgc agggatattt ctttagtgaa aggatagact
     4021 gatgcaggaa tttacaaatc cctttcctat aggctctagt tccctcattc actgcattac
     4081 caatgagatt tcttgtgaga tgctggcaaa tgggattttg gctctgggat gcaaacctgt
     4141 catggcagat gatccccgtg aggttcttga ttttactaag caaagtcagg ctctcttcat
     4201 caatttgggg catttgtcag ctgagaagga gaaagcaatc cgtatagcag cttcttatgc
     4261 agctcaagtt tgtctcccaa tggtagtaga tgcggttggc gtaacgactt catccattcg
     4321 taagagctta gttaaagacc ttttagacta tagacctacg gtccttaaag gaaacatgtc
     4381 agaaattcga agtcttgttg gattaaagca ccacggcgtt ggggtcgatg cgagtgctaa
     4441 agatcaagaa acggaggatt tgcttcaagt cttgaaagac tggtgtcaga cctatcctgg
     4501 tatgtcattc ttagttactg gccccaagga cctcatcgtt tcggagaatc aagttgctgt
     4561 actgggaaat ggctgtgcag aattagactg gataacaggg acaggagatt tggttggagc
     4621 cttaacagcc gtttttctca gccaaggaaa gactggtttt gaagcttctt gcttagcagt
     4681 ctcttatctt aatatcgctg ctgagaaaat agttgttcaa ggaatgggat tggaagaatt
     4741 tcgttaccaa gtactcaatc agctttcgct cctaagaaga gatgaaaatt ggctagatac
     4801 catcaaagga gaggtttatg aatagagaag cacttagact atatctggta accaatcgct
     4861 atcaagattc cgtggaaagc tttcttgcaa aaattgagac ggcctgccgt tcaggggtta
     4921 ccatagtcca attgcgagaa aaaaatctca caaccaatca atattatcaa ctggcaaaac
     4981 aagtcaagga aataacagat gcttatcagg tacccttgat aatcgatgat cggttggatg
     5041 tttgtcttgc ggttgatgct gctggtctgc atattggaga tgacgaactc ccagtttcgg
     5101 ttgcccgaca agtcttgggt cctgaaaaaa tcctcggtgt caccgctaaa acggttaaaa
     5161 gagctctgga agcggagaaa tcaggtgcag attacttggg gacaggagcc atttttccga
     5221 caaccaccaa ggaaaatgca cccatcaccc tgatttcaac cttgaaaaca atttgccaaa
     5281 cggttgccat tccaatagtt gctattggcg gcttgacttc ggagaatatt gatcagctta
     5341 tgggcactgg catagctggt gtagctgttg tacgtgattt gatgcaagca gaagatattg
     5401 aggcaaaaac gcaagccttt ttaacaaagt tgcatgacat tctttcctaa ttaatactca
     5461 atgaaaatca aagagtaaac tagaaagcta gtcgcaggtt gctcaaagta ctgccttgag
     5521 gttttagata agactgacga agtcagctca aaacagtgtt ttgaagttgc agatggaagc
     5581 tgacgtagtt tgaagagatt ttcgaagagt ataaaaactc tctaattccc ttaaagtggg
     5641 aactagagag tttttttctt aatctttaaa agttgtatgg ttgactggac cagaaccatg
     5701 accgagttga ggggcatctt gaatagcttt tgtgataaag gccttggcct tatcaactgc
     5761 ctggtaaaga ctcttgccct tggctagttc agcagtaatc actgcagcaa aggtacatcc
     5821 agtaccatgg gtgtgacagg tttgaattcg tgggctttcc cagacaaatt gttcattctt
     5881 ggtaaagagg aaatctttag caccaccttt gagatgtccg cctttgataa ccacagactg
     5941 aggaccaaat tcttttaaaa tcaggcgacc agcacgctgc atgtcttcgg ggtcatggat
     6001 tgaaaaacca acaatctctt ctgcttcagg aagatttggc gtaataatag ttgctagagg
     6061 tagtaagttt gttttgagat agtctctagc atttgagtca atcaaggcat ctccacttgt
     6121 agcaaccata acaggatcaa ggacataggg acaatccagt tttttaagat agggttggat
     6181 gatttccatg atttcagtag tagccaacat tccagttttt acagcctgag gtggaatatc
     6241 agaaaagaca ctctccaatt gggctttcaa catttgagga gaaacgtgct cgattagctg
     6301 aacacctctg gtattttgag cgacaagact ggttacaaca gccattccat agacatctct
     6361 cgcttggaat gactttaaat ctgccataat gccagcacca ccactagggt cagtccctgc
     6421 aatggtcaaa gcaacgggta aataagtcat ctaaaacctc ccaaccaact gaagtttgta
     6481 ttcttaagaa caagctagtc tgttttagaa aggcaataga agactgctag tccccattat
     6541 catttccact tccatcagct agcattacct agattgagtc agagggatct agcagtcgtt
     6601 aatctcagct ttacgcaccc ctagtggttg ttttcttttt tctttagtat agcatatttt
     6661 tattgtttat atagtaatat ttgactgcaa atcgtttttc aaatgattaa aattctattt
     6721 ttcgaagaaa atattatttc tataattgac aaatgtagat tttaagagta tactgataag
     6781 tgtaattgac aaatgtagat tttggaggta tggtaatgca gatttcagat gcagaatggc
     6841 aggtcatgaa gattatttgg atgcaggggg agcagaccag tacagatttg attagggttt
     6901 tggcagagcg gtttgactgg tccaagtcca cggttcagac acttttggct cgtctggttg
     6961 ataaagagtg tttgactcgg aaaaaagaag gcaagtcctt tgtttattca gcccttttaa
     7021 ctctagacca aagtcgggat ttacttgtcc aagatatcaa agacaaggtt tgttcccgta
     7081 ggattaggaa tttgttggct gacttgattg tagaatgtga atttactcag actgacttgg
     7141 aagacttgga agctgtgatt tcagagaaga aatcaagtgc tgtaacagaa gtaagatgta
     7201 attgtatgta aaggagacgt catgttaaat agtattgtaa ccattatttg tattgctctt
     7261 atcgcgttta tcttgttttg gtttttcaaa aagcctgaaa aatctggaca aaaagcccag
     7321 caaaaaaacg gataccaaga gattcgagtg gaagtcatgg gaggctatac tcctgagttg
     7381 attgtcctca agagatcagt gccagcccgc attgtctttg accgcaagga tccttcacca
     7441 tgtctggatc aaattgtttt tccagatttt ggtgtacatg cgaacctgcc aatgggggaa
     7501 gagtatgtag tggaaatcac gcctgagcag gctggagagt ttggctttgc ttgtggtatg
     7561 aacatgatgc acggcaagat gattgtagag taggtggaga ctatgacaga aattgtgaaa
     7621 gcaagcttag aaaatggcat tcaaaaaatc cgtatccgag ctgaaaaagg ctatcatcca
     7681 gcccatatcc agcttcaaaa ggaaattcca gctgagatta cctttcatcg tgctactcct
     7741 tcaaactgtt ataaggaaat tctgtttgaa gaagaaggta tcttggaacc aatcggcgta
     7801 gatgaggaga aagtcattcg ttttacacct caagaattag ggcgacatga attttcttgt
     7861 ggcatgaaga tgcaaaaggg aagctatata gtcgttgaga agactcgaaa atctctatct
     7921 ctcctgcaac gtttttggat tactagtatc tttactgtgc ctcttgtgat tctcatgatt
     7981 gggatgttga caggtagcat tagtcatcaa gtcatgcatt ggggaacctt tctagcaaca
     8041 acgcctatta tgttagttgc aggtaagcca tatatccaga gtgcttgggc cagttttaaa
     8101 aagcacaatg ccaacatgga taccttggtt gcgctgggaa ctctagtggc ttatttctat
     8161 agcctagttg ctctctttgc tggtctccct gtttacttcg aaagtgctgg atttatcctc
     8221 tttttcgttc ttttgggagc agtttttgag gaaaaaatga gaaaaaatac gtcccaagct
     8281 gtggagaaat tactggactt gcaagctaaa accgcagaag tcttgagtga tgatagttat
     8341 gtccaagttc ctttggaaca agtcaaggta ggcgacctga ttcgagtgcg tcccggtgaa
     8401 aagattgctg ttgatggtgt cgtagtagaa ggtgtctcta gtattgacga atccatggtg
     8461 acaggtgaga gtctgcctgt ggacaagaca gttggagata ctgtcattgg ctcaaccatc
     8521 aatcatagtg gaacgcttgt ctttagagca gaaaaagttg gctcagagac tgttttggct
     8581 cagattgtgg attttgtgaa gaaagctcag acaagtcgtg cgccgattca ggacttgacg
     8641 gataagattt cagggatttt tgtcccagta gttgtcattt taggaatcat gaccttttgg
     8701 gtttggttcg tcttgctcag ggatagtgtg gttgtgcttg gagctagctt tgtgtcctct
     8761 cttctctacg gagtggcggt tttgattatc gcctgtcctt gtgccttggg acttgcaaca
     8821 ccgacagccc ttatggtggg gacaggacgt agtgccaaga tgggggttct cctcaaaaat
     8881 ggaactgtct tacaggaaat ccagaaagtt caaacccttg tctttgataa gaccgggact
     8941 ttgacggaag ggaaacctgt ggtaacagat gtcatcggcg acgaagtaga agtgtttggg
     9001 ttggcagcct ccttggaaga tgcttctcaa cacccactgg ctgaggctat cgttaagcga
     9061 gcgagtgaag ctggacttga gtttcaaact gttgaaaatt ttcagtcctt gcacgggaaa
     9121 ggtgtttcag ggcgaatcaa tggaaaacaa gttttacttg gaaatgctaa aatgctggat
     9181 ggcatggata tttctaatac ttatcaagat aaactagaag aactagaaaa agaagctaag
     9241 acagttgtgt tcttagctgt tgacaatgaa atcaaaggct tgcttgcttt gcaagatatt
     9301 cctaaggaaa atgctaagct agccatcagt cagctaaaaa aacgtggtct ccgaacagtc
     9361 atgctgacag gagacaatgc tggtgtggcg cgtgctattg cagatcaaat cggaattgaa
     9421 gaggtcattg caggcgtctt gccagaagaa aaagcccatg aaatccataa actgcaacag
     9481 tcagggaaag tagcctttgt tggggacggt atcaatgacg ctcctgccct tagtgtagca
     9541 gatgtgggaa ttgctatggg tgctggaaca gatatcgcca tcgagtcagc agatttggtg
     9601 ttgacaacca ataatatttt aggagtggtt cgtgcctttg atatgagtaa gaaaaccttt
     9661 catcgaattc tactcaatct tttctgggct tttatctaca atgttgtcgg aattccgatt
     9721 gcagcaggag tcttttcagg tgttggactg gctctcaacc cagaattggc aggtctagcc
     9781 atggccttta gttctgtatc tgttctgacc agttcccttc tgttaaattt tagtaaaata
     9841 gactaaaagt aatgactaga tttctttgtt ataaaacaga aatgacaaca ctttcaaaac
     9901 tgtattagaa tagagaatag agagttttga gcagattttt agaaaagtca gcataaatat
     9961 gatacagtgg aatagtaaaa atttggagaa cgtttccaat tctatgtaat cgtattctcc
    10021 aagtctaaaa aaattgaagg agagttatca ttatgactca agggaaaatt actgcatctg
    10081 cagcaatgct taacgtattg aaaacatggg gcgtagatac aatctacggt atcccatcag
    10141 gaacactcag ctcattgatg gatgctttgg ctgaagacaa agatatccgt ttcttacaag
    10201 ttcgccacga agagacaggt gctcttgcag cggttatgca agctaaattc ggcggctcaa
    10261 tcggggttgc agttggttca ggtggtccag gtgcgactca cttgattaac ggtgtttacg
    10321 atgcagctat ggataacact ccattcctag cgatccttgg atcacgtcca gttaacgaat
    10381 tgaacatgga tgctttccaa gagcttaatc aaaacccaat gtacaacggt atcgctgttt
    10441 acaacaaacg tgtagcttac gctgagcaat tgccaaaagt aattgacgaa gcctgccgtg
    10501 ctgcagtttc taaaaaaggt ccagctgttg ttgaaattcc agtaaacttc ggtttccaag
    10561 aaatcgatga aaactcatac tacggttcag gttcatacga acgctcgttc atcgctcctg
    10621 ctttgaacga agttgaaatc gacaaagctg ttgaaatctt gaacaatgct gaacgcccag
    10681 ttatctatgc tggatttggt ggtgttaaag ctggtgaagt gattactgaa ttgtcacgta
    10741 aaatcaaagc accaatcatc acaactggta aaaactttga agctttcgaa tggaactatg
    10801 aaggtttgac aggttctgct taccgtgttg gttggaaacc agccaacgaa gtggtctttg
    10861 aagcagacac agttcttttc cttggttcaa acttcccatt cgctgaagtt tacgaagcat
    10921 tcaagaacac tgaaaaattt atccaagtcg atatcgaccc ttacaaactt ggtaaacgtc
    10981 atgctcttga cgcttcaatc cttggtgatg ctggtcaagc agctaaagct atccttgaca
    11041 aagtaaaccc agttgaatca actccatggt ggcgtgcaaa cgttaagaac aaccaaaact
    11101 ggcgtgatta catgaacaaa ctcgaaggta aaactgaggg tgaattgcaa ttgtatcaag
    11161 tttacaatgc aatcaacaaa catgctgatc aagacgctat ctactcaatc gacgtaggta
    11221 acactactca aacatctact cgtcaccttc acatgacacc taagaacatg tggcgtacat
    11281 ctccactctt tgcgacaatg ggtattgccc ttcctggtgg tatcgctgct aagaaagaca
    11341 atccagatcg ccaagtatgg aacatcatgg gtgacggagc attcaacatg tgctacccag
    11401 acgttatcac aaacgttcaa tacgaccttc cagttatcaa ccttgtcttc tcaaatgctg
    11461 agtacggctt catcaagaac aaatacgaag atacaaacaa acacttgttt ggtgtagact
    11521 tcacaaacgc tgactacgct aaaattgcgg aagctcaagg agctgttgga ttcacagttg
    11581 accgtatcga agacatcgat gcagttgttg cagaagctgt taaattgaac aaagaaggta
    11641 aaactgttgt catcgatgct cgcatcactc aacaccgtcc acttccagta gaagtacttg
    11701 aattggatcc aaaacttcac tcagaagaag ctatcaaagc cttcaaggaa aaatacgaag
    11761 cagaagaact cgtaccattc cgtctcttct tggaagaaga aggattgcaa tcacgcgcaa
    11821 ttaaataatt cctctcgtcg aaaatcaaat atgaaacttg tagactttat tctttgattt
    11881 tcatagagca gaactttaaa agatcggagc aatccggtct ttttatggag gagagtaaat
    11941 gaatttaaat caattagata ttatcgtttc aaatgttccc caagtctgtg ctgacttgga
    12001 gcatatcttg gataaaaagg cagattatgc tgatgatggt tttgctcagt ttacgattgg
    12061 tagtcactgc cttatgttgt cacaaaatca tttggttcct ttggaaaact ttcagtcagg
    12121 aatcattatt catatcgagg ttgaggatgt agaccagaac tacaaacggt tgaacgagct
    12181 tggtataaag gttttacacg gaccaactgt aaccgattgg ggaacagagt ccttattagt
    12241 tcaaggacct gctggtctag tgcttgattt ttatcgtatg aaataggtcg cgtagtcatt
    12301 tgacgttaac cttagctatt tttaaaatag aaattgagaa tatgaactat tgaaagatcg
    12361 gagcaatccg gtctttttat ataaagaaat tgcatataat actcatctgc tttcaaaaag
    12421 cattctagtc catctccgat taacgatgga ctttatcacc tccttctcca atccttgtat
    12481 gacatcttgg agttgatt
//
LOCUS       DAVHKZ010000051        11652 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000051 DAVHKZ010000000
VERSION     DAVHKZ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11652
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.051"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            131..385
                     /gene="blpM"
                     /locus_tag="VVO74_001928"
     CDS             131..385
                     /gene="blpM"
                     /locus_tag="VVO74_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEU5695911.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            401..604
                     /gene="blpN"
                     /locus_tag="VVO74_001929"
     CDS             401..604
                     /gene="blpN"
                     /locus_tag="VVO74_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEU5695912.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            848..997
                     /gene="blpO"
                     /locus_tag="VVO74_001930"
     CDS             848..997
                     /gene="blpO"
                     /locus_tag="VVO74_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEU5695913.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1101..1220
                     /locus_tag="VVO74_001931"
     CDS             1101..1220
                     /locus_tag="VVO74_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU5695914.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            2006..2389
                     /locus_tag="VVO74_001932"
     CDS             2006..2389
                     /locus_tag="VVO74_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU5695915.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            2441..3130
                     /locus_tag="VVO74_001933"
     CDS             2441..3130
                     /locus_tag="VVO74_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5695916.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3172..3405
                     /locus_tag="VVO74_001934"
     CDS             3172..3405
                     /locus_tag="VVO74_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695917.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFLGAGYVVGFWLLILNENQRAN"
     gene            3556..4167
                     /locus_tag="VVO74_001935"
     CDS             3556..4167
                     /locus_tag="VVO74_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5695918.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFVPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYKSWPLLYYL"
     gene            4328..5122
                     /locus_tag="VVO74_001936"
     CDS             4328..5122
                     /locus_tag="VVO74_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU5695919.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETVPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5119..5754
                     /gene="trmB"
                     /locus_tag="VVO74_001937"
     CDS             5119..5754
                     /gene="trmB"
                     /locus_tag="VVO74_001937"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU5695920.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            5880..6359
                     /gene="rimP"
                     /locus_tag="VVO74_001938"
     CDS             5880..6359
                     /gene="rimP"
                     /locus_tag="VVO74_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU5695921.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            6403..7539
                     /gene="nusA"
                     /locus_tag="VVO74_001939"
     CDS             6403..7539
                     /gene="nusA"
                     /locus_tag="VVO74_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU5695922.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7561..7854
                     /locus_tag="VVO74_001940"
     CDS             7561..7854
                     /locus_tag="VVO74_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU5695923.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            7847..8146
                     /locus_tag="VVO74_001941"
     CDS             7847..8146
                     /locus_tag="VVO74_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU5695924.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8163..10955
                     /gene="infB"
                     /locus_tag="VVO74_001942"
     CDS             8163..10955
                     /gene="infB"
                     /locus_tag="VVO74_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU5695925.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11206..11556
                     /gene="rbfA"
                     /locus_tag="VVO74_001943"
     CDS             11206..11556
                     /gene="rbfA"
                     /locus_tag="VVO74_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU5695926.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3579 a         2023 c         2650 g         3400 t
ORIGIN      
        1 taatttttgc aattcaagac gtttcgatga ctattcaaga tctggatgaa aaattttaaa
       61 aaacgatgat atactaaact tgtcaaagtt acaacaagac aaaaattaaa aataaaaaag
      121 agtatttgtc atggatacaa aaattatgga acaatttcat gaaatggata taactatgtt
      181 atctagtatt gaaggaggca agaataattg gcaaactaat gtcttagaag gtggtggtgc
      241 tgcttttggt ggctgggggc tagggacagc tatttgtgct gcgagtggtg ttggagcacc
      301 atttatggga gcatgtggat acataggagc taaatttggt gtggatcttt gggcaggagt
      361 aacaggggca acgggtggat tttaataaaa ggagacttgt atgaatactt attgtaatat
      421 aaatgaaaca atgctgagtg aggtttatgg aggtaattcc ggaggagcag ctgtagttgc
      481 tgctttaggt tgtgcagcgg gtggagtgaa atatgggaga cttctaggac catggggcgc
      541 tgcaatagga ggaattggag gagcagtggt ttgtggatat ttagcctata ccgctacatc
      601 ataaaaatga aagctaaatt ttatgaaggc tatattcttt attattctct tcgcttttca
      661 aacctatctt atttatctat ccataagtat ctccgataaa aaacaaaaga ctattgaatt
      721 aacatcattg aattgttttg tcatattatt tctaatctat gataaattaa tttttctctt
      781 tattgcctat gtttttttga taatttttat attaaacttg ttccgtaact gaaaagtgat
      841 atactatatg gatacaaaaa tgatgtcaca atttgcagtt atggataatg aaatgcttgc
      901 ttgcgttgaa ggtggagata ttgattgggg aagaaaaatt agttgtgcag caggggttgc
      961 atatggcgca attgatgggt gtgcaacaac ggtttgacat ttctattggg accatttgct
     1021 ataggaatag gtgtaactgg tgctgcggga ggagctatac ttggaggtgt ggcctatgca
     1081 gcgacatgtt ggtggtaatt atggatttta aaagttttat tattggttta gtagttggta
     1141 tatttggtcc ttatatggat gacttaatta gaaaaatatt ttcaaaatct tccaaaaagg
     1201 atacggatag tactctctaa aaaataaatt tctcccctgt atttgctagc ttaatttaca
     1261 ggggagtttc tttaatattg tttcgcctgt caaaatgata tgtgatagca ggatgaaaag
     1321 tctacaaaca agttggtatc aatacaatat aaagaggaaa gtatgttttt aatgcttact
     1381 ttttaaattt tttaacaatt caagatgttt cgatgacaat tcaagatttg gatgaaaaat
     1441 tttaaaaaac aatgatatac taaacttgtc aaagttgcaa cgggtgctgc tacattatgt
     1501 taaaaatcgc tcttgattga taagttggat ttgttaggaa aggagtaaat aattatggat
     1561 aagaaaaaga tagtttcgac tataatatgt atagtatttc ttgtagtgtc agtagataat
     1621 ttttttagag acttaacccc gttactgttc attttaaata ttattggcct gtcttgcttt
     1681 tcagtgctaa catacattaa cataaaagag atactcttaa atataagtaa atgatgattt
     1741 ggttagtcct agaaccaatc aacttatgtt tatcggcttg gcagatttta tgtttgtcat
     1801 ttgtttgtat agaggtattt cagaaacaga attctatcaa caactaatcg cttatatagg
     1861 tgtattctct gcttgtttat cacgcttctg ctcatgtggg gcttgaagta ttataaaaag
     1921 tagctttcta tccttttctg acaggatatt tgagtagaag gctctattaa attgttagtg
     1981 aaataaatga atggaggtat ttaatatgaa atacagatta ttttttgtta ttttcttgag
     2041 tagtgtgttg gatattcttt tagggacatt tttacaaatc tctatcgtat ctattgggtg
     2101 gcttgttctt tacagtggtt tgtttgaagc aggagttttc cttcttgcta ataaaggggt
     2161 ggcggtaaaa atcaaggaag tagatattcg aaatcgcttt aaatttattt ttggaaaaac
     2221 cttatggttt caaattcttt tgctcatctt tttgataatc aaactttatc ttggtttgga
     2281 tgcgaggttg attttattct atggacatat tttcattgtc tttaatgcct taatgtatct
     2341 attatctagt agtcaggtta gccttaaaaa aaacaaactg tcttcttaat cttacagcag
     2401 tagagcctga caaggtgagg tcatagtagg gaggatttct atgaaaaagt atcaacttct
     2461 attcaaaata agtgcagtct tctcttactt atttttcgta tttggtcttt ctcagctgac
     2521 gcttatcgtc caaaactatt ggcaattttc ttctcagata ggcaatttat tctggattca
     2581 aaatatcttg agtttacttt ttattggagt catgattgtg gttcttgtta agacaggcca
     2641 tggttatctc ttccgcattc caagaaaaaa atggctttgg tattcgattt tgacagtatt
     2701 agtggtagtg ttacagatct cttttaacgt tcagacagct aaacatgttc agtcaactgc
     2761 ggaaggttgg gctgtattga ttggttatag tgggactaac tttgcagagc taggtattta
     2821 tatagccctg ttctttctgg ttccactgat ggaagaattg atttatagag gattactgca
     2881 acatgctttc tttaagcatt cgcgatttgg tcttgatttg cttcttcctt ctattttatt
     2941 tgctctccct catttttcaa gcctgcctag tctgttagat atcttcgtct ttgcaacagt
     3001 tggaatcatc tttgctggtt tgacccgcta taccaagagc atttatccat cctatgcggt
     3061 gcatgtgatc aataatattg tagcgacctt cccgtttttg ctcacttttc tacatagggt
     3121 cttggggtaa aaaaacaaaa ggcttgcttt tcagccatag aggaggtcat catgtataaa
     3181 cacttatttt tcctagattc caaaacttta gatcggttga caccctatat tctagtcttg
     3241 gcttctgaca ccattgcttt taatgttttt gtgctaacct ttgtatctgc ggtggttttt
     3301 aatttcctaa attccatgct agctttaatg gctatcttct taggagctgg ctatgtggtc
     3361 ggattttggt tactaatact caatgaaaat caaagagcaa actaggaaac tagccgcagg
     3421 ctgtacttga gtacggcaag gcgacgttga cgtggtttga atttgatttt cgaagagtat
     3481 aaaatggttt gttttggaaa ggctagaact aaaggatgac gtgtaggaag tctgtttgtt
     3541 gaggaggata attttatgga gttttttgat aaatttcatg ccttgtgttt tggattttta
     3601 gtactaataa ttgtcattac agttccttat acgattaacc atggggattt ttttcaaaat
     3661 gaatctgcat tgattattgt aagtcttctt gtaacctcgc tgagtgttgc ttatgctaga
     3721 aagtttgaaa tgatttcttt tgggatgtta agcaagaaac aacttttgct tttcattgca
     3781 atctttcttc taagtgtgct tgagacgctg gtttatattc atttcttcgc tgtttcttct
     3841 ggctcagggg tccaacactt ggcggaagtc agcagaggaa tttccctgtc tttgattttg
     3901 actacctcag tttttgtccc catccaggag gaactcattt tcagaggact tcttcaaggt
     3961 gcggtttttg acaattcttg gttagggctt gtgctaactt cctctctctt ttctttcatg
     4021 catggacctt ctaatgtccc ttcgtttatt ttttatctac ttgggggctt gttactgggc
     4081 tttgcttata aaaagagtca aaacctatgg gtttctactc tagtacatat gctttacaaa
     4141 agttggccac tcttatatta tttataaaaa ttatgaaaag gtaagcagaa gacggtgctt
     4201 acctttttca agctataatg atacccaagc caatccagag gcttttcttt gagaatcggg
     4261 ttagagtggt tgacgaatag gccaaaaact agtagaatag taaggaaact ttatacggag
     4321 gaaagaaatg gatttgggtg ataatgagct aacactgact cccatacctg ggaaaagtgg
     4381 caaggcttat atgggtagct atcctgatgg gaagcgcatc tttgtaaaaa tgaacacctc
     4441 tccaatccta cctggtctag ctagagaaca aattgctcca caattattat ggagtcgtcg
     4501 tttggcagat gggcgtgata tgtgtgctca agaatggttg acaggcaaga tattgacccc
     4561 ctatgatatg aatcgtaagc aaatcgtcaa tattttaacc cgtcttcatc gctcacgtcc
     4621 gttgatgaca caattgagtc gtttgggcta tgccatggaa acacctgtag atttactaca
     4681 gtcttggcag gaaacggttc cagatgcttt gcgtaaaaat cattttatca gtgaagtgat
     4741 ggctgattta cgtcagacta ttccaggatt tagagaggac catgcgacca ttgtccatgg
     4801 agatgtacga catagtaatt ggattgagac agatagtggc ttgatttatt tagtagattg
     4861 ggattcggtt cgcttgaccg atcgcatgtt tgatgtggcc catatgctct gccattatat
     4921 ttcagaacat cagtggaagg aatggttgac ctactacggt tacaagtaca atcaaacggt
     4981 attaagtaaa ttgtattggt atggtcaatt gtcttatttg agtcagattt ccaagtatta
     5041 tatgaaccaa gatttagaaa atgtcaatcg ggagattcat ggtttgcgtc atttccgaga
     5101 caagtatgga aagagaagat gagagttaga aatcgtaaag gggcaacaga attactagag
     5161 gcaaatcccc agtatgtggt cctcaatccc ttggaagcca aggcaaaatg gcgggacttg
     5221 tttggcaatg ataatcccat tcatgtggaa gttggaagtg gaaagggtgc ctttgtttca
     5281 ggtatggcca agcaaaaccc tgacatcaac tatatcggga ttgatattca aaagtctgtt
     5341 ttgagctacg ctttggacaa ggtgcttgaa gctggagtgt ctaacatcaa gctcttgtgg
     5401 gtagatggtt ctgacttgac tgactacttt gaagacggtg agattgatcg cttgtatctg
     5461 aacttttcag atccatggcc gaaaaaacgc catgaaaagc gtcgtttgac ctacaagacc
     5521 tttttggata ccttcaaacg tatcttgcct gaaaatggag aaattcattt caagacggat
     5581 aaccgtggct tgtttgagta cagtttagtg agcttttctc aatatggcat gaaactcaat
     5641 ggtgtctggc tagatttgca tgccagtgat tttgaaggca atgtcatgac agaatacgag
     5701 caaaaattct caaacaaggg gcaagttatc taccgagttg aggcagaatt ttaagagata
     5761 gcctaaaatt aggctgtaca agtgcttttg ctttacataa gttggcaaac gtgctatact
     5821 gatagtaaga atatgaaaag tgaggcgggg aaatatcttc gcctcttgct tatgaggagg
     5881 tggacgcaat cgcaacaatc gtagaattag tcagagaagt tgtagaacct gtcatagaag
     5941 ctccttttga actcgtggat atcgagtatg gaaagattgg cagtgacatg attctcagta
     6001 tttttgtaga taaacccgaa ggaattacct tgaacgacac ggcagacttg acagaaatga
     6061 tcagtcctgt cctagacacc atcaagccag atcccttccc agaacaatat ttcctagaaa
     6121 ttaccagtcc aggtttggaa cgtcctttga aaaccaagga tgccgtagct ggagcggttg
     6181 gaaaatacat ccatgtcggg ctctaccaag ccatcgataa gcaaaaggtc tttgaaggaa
     6241 ctttgttggc cttcgaagag gacgagttga ctatggaata tatggacaag acgcgtaaga
     6301 aaaccgtcca aattccatac agtttagtat caaaagcacg tttagcagtt aaattataga
     6361 aaaagaaagg atagcttttg aggattcaaa agtgaagaaa acatgagtaa agaaatgcta
     6421 gaggccttcc gcattttgga agaagacaag ggaatcaaaa aagaagatat catcgacgca
     6481 gtagtagagt cgcttcgttc cgcttatcgc agacgctatg gtcagtcaga cagcgtagct
     6541 attgacttca acgaaaaaac aggtgacttt acagtttata ctgtccgtga agttgttgat
     6601 gaagtatttg atagccgttt ggaaatcagc ttgaaagatg ctcttgccat taattcagct
     6661 tatgaacttg gagacaaaat caagtttgaa gaagcaccag ctgagtttgg tcgtgtagca
     6721 gcccaatctg ccaaacaaac catcatggaa aaaatgcgca agcaaacacg tgccatcact
     6781 tacaatactt acaaagaaca tgagcaagaa atcatgtctg gtacagtaga acgctttgac
     6841 aaccgcttta tctatgtcaa ccttggtagt atcgaagccc aattgtcaaa acaagaccaa
     6901 attcctggag aagtttttgc ttctcatgat cgtatcgaag tttatgttta caaggttgaa
     6961 gacaaccctc gtggtgtgaa cgtctttgtt agccgtagcc atccagaaat gatcaaacgt
     7021 ttgatggagc aagaaattcc agaagtttat gatggaactg ttgaaatcat gagcgtggct
     7081 cgtgaagcag gtgaccgtac gaaggttgct gttcgtagcc acaatccaaa cgtggatgct
     7141 atcggtacaa tcgttggacg tggtggtgct aatatcaaga agattactag caaattccac
     7201 ccagctcgtt acgatgctaa aaatgaccgc atggtaccaa tcgaagaaaa tatcgatgtt
     7261 atcgagtggg tagcagatcc agctgaattt atctacaatg ccatcgctcc tgctgaggtt
     7321 gaccaagtta tctttgatga aaacgacagc aaacgtgcct tggtggttgt tccagataac
     7381 aagctttctc ttgccattgg tcgtcgtgga caaaacgtgc gcttggcggc tcacttgact
     7441 ggttaccgta tcgatatcaa gtctgctagc gaatttgaag ccatggaaga cgctgcttca
     7501 gtagagttgg aagtagaaaa cgatactgta gaagaataaa agctgctaga ggagggaaag
     7561 atgaaaacaa gaaaaatccc tttgcgcaag tctgttgtgt ctaacgaagt gattgataag
     7621 cgtgatttgc tccgcattgt caagaacaag gaaggacaag tctttattga tcctacgggc
     7681 aaggccaatg gccgcggcgc ttatatcaaa ctagacaatg cagaagccct agaggcgaaa
     7741 aagaagaagg tctttaaccg cagctttagc atggaagtgg aagaaagctt ttatgacgag
     7801 ttgatcgctt atgtggatca caaagtgaaa agaagagagt tgggacttga ataagcaaaa
     7861 gataagtaat ctcttggggc ttgctcagcg agcagggcgc atcatatcgg gtgaagaatt
     7921 ggtggtcaag gccattcaag acggcaaggc caagttggtc tttctagctc atgatgctgg
     7981 acccaatctg accaagaaga ttcaagataa aagtcattat tatcaagtag aaattgtaac
     8041 cgtgttttca acactggaat taagcatagc agtcgggaaa tcgagaaagg ttttggctgt
     8101 aacagatgct ggatttacaa agaaaatgag gtctcttatg gaatagaaga ggaggacatg
     8161 atttgtctaa gaaaagattg tacgaaatcg caaaagaact tggaaaagaa agtaaagaag
     8221 ttgtagcgcg tgcaaaagag ttaggcttgg atgtgaaaag ccactcatca agtgtggaag
     8281 aagctgtcgc tgcaaaaatt gctgccagct ttaagcctgc agctgctccg aaagtagaag
     8341 caaaacctgc agcaccaaaa gtaagtgcag aaaagaaagc cgaaaaatct gagccagcta
     8401 aaccagctgt agctaaggaa gaggcaaaac cggctgagcc agttgctccg aaaacagaaa
     8461 aagtagcagt gaaaccgcaa agtcgtaatt tcaaggctga gcgtgaagcc cgtgctaaag
     8521 agcaggcaga acgacgcaag caaaataagg gcaataaccg tgaccaacaa caaaacggaa
     8581 accgtcagaa aaacgacggc cgtaatggtg gaaaacaagg tcaaagcaac cgcgacaatc
     8641 gtcgctttaa tgaccaagct aagaagcagc aaggtcagca aaaacgtaga aatgagcgcc
     8701 gtcagcaaga ggataaacgt tcaaatcaag cggctccacg tattgacttt aaagcccgtg
     8761 cagcagccct aaaagcagag caaaatgcag agtacgctcg ttcaagtgag gaacgcttca
     8821 agcagtatca ggctgctaaa gaagccttgg ctcaagctaa caaacgcaag gaaccagagg
     8881 aaatctttga agaagcggct aagttagctg aacaagcaca gcaagttcaa gcagtggttg
     8941 aagtcgtccc tgagaaaaaa gaacctgcag tggatacacg tcgtaaaaaa caagctcgac
     9001 cagacaaaaa tcgtgacgat tatgatcatg aagaagatgg tcctagaaaa caacaaaaga
     9061 atcgaagtag tcaaaatcaa gtgagaaatc aaaagaatag taactggaat aacaacaaaa
     9121 agaacaaaaa aggcaataac aagaacaacc gtaatcagac tccaaaacct gttacggagc
     9181 gtaaattcca tgaattgcca acagaatttg aatatacaga tggtatgacc gttgcggaaa
     9241 tcgcaaaacg tatcaaacgt gaaccagctg aaatcgttaa gaaacttttc atgatgggtg
     9301 tcatggccac acaaaaccaa tccttggatg gggaaacaat tgaactcctc atggtggatt
     9361 acggtatcga agccaaacaa aaggttgaag tggataatgc tgacatcgaa cgtttctttg
     9421 tcgaagatgg ttatctcaat gaagatgaat tggttgagcg tccaccagtt gttactatca
     9481 tgggacacgt tgaccacggt aaaacaaccc ttttggatac tcttcgtaac tcacgtgttg
     9541 cgacaggtga agcaggtggt attactcagc atatcggtgc ctaccaaatc gtggaaaatg
     9601 gtaagaagat taccttcctt gatacaccag gacacgcggc ctttacatca atgcgtgcgc
     9661 gtggtgcttc tgttaccgat attacgatct tggtcgtagc ggcagatgac ggggttatgc
     9721 ctcagactat tgaagccatc aaccactcaa aagcagctaa cgttccaatc atcgtagcta
     9781 ttaacaagat tgataaacca ggtgctaacc cagaacgcgt tatcggtgaa ttggcagagc
     9841 atggtgtgat gtcaaccgct tggggtggag attctgaatt tgttgaaatc tcggctaaat
     9901 tcaaccaaaa tatcgaagaa ttgttggaaa cagtccttct tgtggctgaa atccaagaac
     9961 tcaaagcaga cccaacagtt cgtgcgatcg gtacggttat cgaagcgcgc ttggataaag
    10021 gaaaaggtgc ggtcgcaacc cttcttgtac aacaaggtac cttgaatgtt caagacccaa
    10081 tcgttgtcgg aaataccttc ggtcgtgtcc gtgctatgac caacgacctt ggtcgtcgtg
    10141 ttaaagttgc tggaccatca acaccagtct ctatcacagg tttgaacgaa gcaccgatgg
    10201 cgggtgacca ctttgccgtt tacgaggatg aaaaatctgc gcgtgcagca ggtgaagagc
    10261 gtgccaaacg tgccctcatg aaacaacgtc aagctaccca acgtgttagc cttgaaaacc
    10321 tctttgatac ccttaaagct ggggaactca aatctgttaa tgttatcatc aaggccgatg
    10381 tacaaggttc tgttgaagcc ctttctgcct cacttcaaaa gattgacgtg gaaggtgtca
    10441 aagtgactat cgtccactca gcggtcggtg ctatcaacga atcagatgtg acccttgccg
    10501 aagcttcaaa tgcctttatc gttggtttca acgtacgccc tacaccacaa gctcgtcaac
    10561 aagcagaagc tgacgatgtg gaaatccgtc ttcacagcat tatctacaag gttatcgaag
    10621 agatggaaga agctatgaaa gggatgcttg atccagaatt tgaagaaaaa gttattggtg
    10681 aagcggttat ccgtgaaacc ttcaaggtgt ctaaagtggg aactatcggt ggatttatgg
    10741 ttatcaacgg taaggttgcc cgtgactcta aagtccgtgt tatccgtgat ggtgtcgtta
    10801 tctatgatgg tgaactcgca agcttgaaac actataaaga cgacgttaag gaagttacaa
    10861 acggccgtga aggtggattg atgatcgacg gctacaatga tattaagatg gatgatgtga
    10921 ttgaggcgta tgtcatggaa gaaatcaaga gataagattt tttgctcctt tcttaggtgg
    10981 tgagggacgc aagcaaaccg atggtttcat tgcttatttt tgagcctagg gtctcaaaaa
    11041 taccctgtga tgggactgat aaatcagttc catcactttc accacggcga aagaagcaga
    11101 tgacttcaaa ttgaacttcg tttcaattta aactgaaaat caagaagttt aaaatagcta
    11161 ggtctgctgg cctagctttt ggttcaaagt agagaaagga atatcatggc aaatcatttc
    11221 cgtacagatc gtgtgggcat ggaaatcaag cgtgaagtca atgagatttt gcaaaagaaa
    11281 gtccgtgatc cacgtgtcca aggtgtgacc atcacagatg ttcagatgct gggtgacttg
    11341 tctgttgcca aggtttatta caccattttg agtaaccttg cttcggataa ccaaaaagcc
    11401 caaatcgggc ttgaaaaagc aactggtacc atcaaacgtg aacttggtcg caatttgaaa
    11461 ttgtacaaaa tcccagattt gaccttcgtc aaagacgagt ccatcgagta tggaaacaag
    11521 attgacgaga tgctacgcaa tctggataag aactaaagaa gaggggttgc ccctcttttt
    11581 tggtggagga aaataggttg aatttgaaat ggaaaaatat tcttttataa tagattgaaa
    11641 ctagaatagt ac
//
LOCUS       DAVHKZ010000052        11189 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000052 DAVHKZ010000000
VERSION     DAVHKZ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11189
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.052"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..627)
                     /locus_tag="VVO74_001944"
     CDS             complement(<1..627)
                     /locus_tag="VVO74_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU5695927.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     TLIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDM"
     gene            1251..1373
                     /locus_tag="VVO74_001945"
     CDS             1251..1373
                     /locus_tag="VVO74_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU5695928.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAG"
     gene            1443..1808
                     /locus_tag="VVO74_001946"
     CDS             1443..1808
                     /locus_tag="VVO74_001946"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU5695929.1"
                     /translation="MPNSESTKPKTFEIDCLVGKKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            1805..2995
                     /locus_tag="VVO74_001947"
     CDS             1805..2995
                     /locus_tag="VVO74_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU5695930.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGSDM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(3510..4502)
                     /locus_tag="VVO74_001948"
     CDS             complement(3510..4502)
                     /locus_tag="VVO74_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5695931.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            4662..6416
                     /locus_tag="VVO74_001949"
     CDS             4662..6416
                     /locus_tag="VVO74_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695932.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNEGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            6400..8121
                     /locus_tag="VVO74_001950"
     CDS             6400..8121
                     /locus_tag="VVO74_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695933.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            8132..8761
                     /locus_tag="VVO74_001951"
     CDS             8132..8761
                     /locus_tag="VVO74_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU5695934.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYIVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            8662..9219
                     /locus_tag="VVO74_001952"
     CDS             8662..9219
                     /locus_tag="VVO74_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU5695935.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            9207..10571
                     /locus_tag="VVO74_001953"
     CDS             9207..10571
                     /locus_tag="VVO74_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695936.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
     gene            complement(11026..11184)
                     /locus_tag="VVO74_001954"
     CDS             complement(11026..11184)
                     /locus_tag="VVO74_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEU5695937.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
BASE COUNT         4103 a         1568 c         1900 g         3618 t
ORIGIN      
        1 catgtcgtaa aggtcgtatt tccaacggca tgactgagaa catccaccac ggttggcatc
       61 acgcatactc atgtggtttg aaagagtaca acgtccagag tatgaaatac acatagctcc
      121 atggacaaag gcttcaattt caacatctgt acgtttgcgg atttcagcta attcttccat
      181 tgaaacctca cgcgctaaaa cgacacgagt caagcctagc tctttccaga actcaagggt
      241 ttcatagtta gtggcactgg cttgggtaga aaggtggatt tcaaggcctg gtgcttcagt
      301 cgctgcaatc ataatcaagg ttgggtcaga tacgataact gctgcaatcc cgatatcacg
      361 cagtttacgg aaccactcac cagcaccagc ttcatttcct tcgtgcataa ccatattagc
      421 cgctacatag accttggcac catacttggc cgcaaactgc acgccttctt ccatctgttc
      481 gaaagtaaag tttcccgcac ggctacgaag accataggcc tgaccaccga taaagacagc
      541 atctgctcca tactgaacag ctacctttag cttctctaaa gtccctgcag gtgataaaac
      601 ctcaggacgt tttaatgttt ttgtcataat ttctcctatt tgcaatataa aagtttgaca
      661 tttttccttc tcattttata gtaaataaag gataaaatca agcctagacg gattgttttg
      721 acaattctaa tcttttagac tttgcataat aactgttaaa cagtcgaaaa ttatcccagt
      781 tttaacaagt agtcaaaaag tctagaaaag taaaaaccag tatccaaaga tactgactcg
      841 taaaaataca taaattagtc cttagatgac tactcccact ctgttgctcc tataatggaa
      901 aaggattgat acagtctaga atatcgcttt tttatttatt attctgatat aaaactgtta
      961 gaattgattt tttgttttat acccaaatat gaatagagac gtagctaata agttgaataa
     1021 catatttgga aaaatgagaa atagcaatat tactagaact tttagaaaca atcaatattt
     1081 aaaaagaaaa aagctcaaag aatttattaa accatgttat aatagatata gctataattt
     1141 tatttataac aagaggatag aaatgaccga attagaaaga aaaaatcgaa aaattagcta
     1201 agaaatattc tgataactta aacatcaaag ttcaagagag agttcgtgaa atggcaaatg
     1261 ataataagag ccattatttg atatacagag ttttaggtat ttcatttgaa gaaggagaaa
     1321 atatcgattt gtatcaaaat aaaggtcgtt ttttatacaa atatgctggt taatttttag
     1381 aagaagctgc agtactatcc tttaacgaaa aatttggtac agaaaatact taaaaagtta
     1441 acattcctaa ttctgaaagt acaaaaccta agacttttga aattgattgt ttagtcggaa
     1501 aaaaacacgc atacgaaata aaatggtggg atgcaactac agatggagac catataacta
     1561 aagaacacac tagaataaaa gttattcata acaaaggata tataccaatt cggttaatgt
     1621 tctactatcc aaatagaact caagctataa aaattcagca aactttagaa acattgtata
     1681 acggtattgg agggaaatat tattatggag attctgcctg ggaacattta agagcagtga
     1741 ccggtattga tttacttagt attctaacag atattgcaaa taaaaaaaca ggggtaaaat
     1801 caaaatgaca gtattaaaag gagataactt agaaatatta aaaactattg aatcctcaag
     1861 tattgattta atctatatgg accctccttt ctttacacag aaaacccaaa aattatctaa
     1921 taacaaaaat attatgtatt cattcgaaga tacgtggact tcgattgagg attacaaaga
     1981 atttttgtct gtaagattag aagaatgcaa aagagtgcta aaaaatagtg gcagcatttt
     2041 cgttcattgt gataaaattg caaatcatca tattagatta attttagata atatctttgg
     2101 atcagatatg tttcaaagcg aaattatatg gaactataaa cggtggtcta attcaaaaaa
     2161 gggattattg aacaatcatc aaaacattta cttttattca aagtcaaaag attttaaatt
     2221 taatacaatt tttacagagt attcttctac tacaaatatc gaccaaatac tagtggaacg
     2281 aaaacgagat ggaaactcta aaactatata taaagttgat aataatggta actatattct
     2341 agcaaaagag aaaaatggag ttcccctttc agatgtttgg aatataccat ttcttaatcc
     2401 aaaagctaaa gaaagagtag gttatcctac acaaaaacct attctgttat tagaacaaat
     2461 tataaagatt gctactgata aaaatgatat agttttagac ccgttctgtg gaagtggaac
     2521 tactttagta gcctccaaga ttttgaatag aaattatatg gggattgatt tatctgagga
     2581 agctatcaat ataactcagc aacgtctgga aaatgttata aaaacaagtt caaatttatt
     2641 gaataaagga atcgaagcat atagaaccaa aactgaggaa gaggaaaaca ttcttaaatt
     2701 attacaggca aaaattgttc aaagaaataa aggaattgat ggttttttac ctaaacattt
     2761 tcaaaaaaaa ccgataccta taaaaattca aaaaaataat gaatgtctga atgagagtat
     2821 ctctttatta cagaatgcta taaactccaa aaaacttgat tttggagtag ttataaaaac
     2881 tcattcagat aatttattat ttgattttga tacgattcct gaaaatataa tagtagttga
     2941 ccattttgaa cttacaatcg aaaaatggtt aagtaaaagt caacagttac tatagtttgc
     3001 aaattattta cagaaagaac aaaaatgctc tgaaacactg atttcaaagc atttttttgt
     3061 tagtttaaaa ttactcccat tcttcttttc caaacgtaca atatatccaa aaccattcaa
     3121 aatactagat tctatttttt ataatatcac taaatccacc taattatagg acgttttcag
     3181 atttttagtc ccgtcccagt cccagtaccg gagaaatatt gttttaatat aatatctctt
     3241 tttgtcttct aagctcttaa aagcaaaaga acaagtaaag agtcaagaca aggataaaaa
     3301 gtccatatta gggcaaataa aaagctttaa gacagatgac aaatctaagt caaataagaa
     3361 agaccatagc aaaggtgcag agagataaat attggcggtc ttcggactgc ctttattttt
     3421 ttatccattt ttcaaatcaa atttattcag actatatatg cacatataca cttaaattca
     3481 tataaaaaca tggcttgtaa aaaattactt taatcacaat aatcgcattt aaaattgtga
     3541 tgtttgcaag ctaaattacg gacttcactt ggaagttttc ccttgtatct tttataatag
     3601 atagaaaatt tgctggcaga tgaatatcca acagattctg ctatctcttt tataggtagt
     3661 tcagtgttta aaagaagagt ttcagctaca ttcattcttt ttctttgagt gtactctgta
     3721 atgctttgac aatatttttc cttaaataaa ttttttaatt tagtaccact cattttagat
     3781 attttttcaa gcgtgccttg atttacattc gttgcaaaat gatcatctaa gaatcttgct
     3841 acatcttcaa gtgctttatc atcatcaatt tcaattttat atttttttct atttaagtat
     3901 gtgtcaatta ctatacttat ccattcattt gcctttgctt taaagaaaaa atcagcggca
     3961 ggagcgtcca tcttacaatt taatatttcc attgccactc tttctaaggc ctttgtaagt
     4021 attatttgat tcggttgaag caaggttgaa taaaaagatt ctggattaat gttaatagat
     4081 gctaaatgtt tttctattag ctctttttta aaaccaatgg aaacagcaag ataacaacaa
     4141 ttctcgtgta ataaaaaaac aaaatcatct tttatattat caaaatcaaa agtacataga
     4201 gagtttgcgg taatagtttg atacggatta aacttttctc cgtttgcact gacaatgtaa
     4261 cttgaataaa ttgaaacata gtctgacata ctataagtgc tattttgaac tacttcctct
     4321 ttgatataaa aatcatgtat atcgataatg aagctgcctc cttcataaaa ccaatatagg
     4381 ccttctgcat aagttgaatt ctcttttttc caacaaaatg tatgacctgc acttgaatac
     4441 ttctcattgt ttttacattc atctactttc atataatctt ttacaaaatc ataatatgac
     4501 ataacacact atccctttta gacaatattc caattagcct tattaattca aaactattgt
     4561 attagtaatt ataacagatg tataatagaa aagcaatgat agatattatc aattaagcga
     4621 atttatatct aaaagggata ttaaagaaag gagatatgct tatgaagatt tacaaaaaac
     4681 tatttgctta tgtccaagat aagaaatatc ttggggtttt ggccataatt ttttctgcta
     4741 tatctgctct acttacagta tatggatatt atttaatcta caaatttcta gataagttaa
     4801 taattaattc aaatttatcc ggtgcagaga gtatagcatt aaaatctgtt attacactaa
     4861 caagtggagc gatattttat tttgtctcag gaatgttttc acatatcttg ggattcaggc
     4921 ttgaaacaaa tttaagaaaa aggggaatcg atggtctgga aaaagcaagt tttaggttct
     4981 ttgacttaaa tccatctggt caaataagaa agatcataga tgataatgca gcacaaactc
     5041 atcaggtggt agcacacatg attcccgata gttctcaggc aataatcaca cccgtacttg
     5101 tacttgcact tggctttata gtaagtataa gagttggcat aattttgctt gctcttacta
     5161 taattggtgg cttaatttta ggggcgatga tgggcgagca agaatttatg aagatatacc
     5221 aagaatccct atctaaacta agtgctgaaa ctgttgagta cgtgagagga atgcaagttg
     5281 taaaaatatt taaagcaaat gtagagtcat ttaaaagctt ttacaaggct ataaaagatt
     5341 actcaaagta tgcttatgat tattccctat cttgtaaaag gccttatgtt ttgtatcaat
     5401 ggttattttt tggactgatt gcaattttaa ttattcctat agtttatttt atgactagct
     5461 tagctagcgc aaaggtgatt ttacttgagc ttatcatgat tttattttta tcaggagttc
     5521 tctttgtttc attcatgaga atgatgtggt actccatgta tatttctcaa ggaaattatg
     5581 cagtagatac tttagaggcg ctttacgaag atatgcaaaa agacaaatta gtgcatggta
     5641 atgtcaataa ttttaaaaac tataatatag aatttgagaa tgttagcttt gcttataatg
     5701 ataaagctgt cattgaaaat ttatccttta atttagaaga aggaaagtcc tacgcacttg
     5761 tcggttcatc tggatcaggc aaatcaacag tagcaaaact tatatcaggt ttttacaatg
     5821 ttaatgaagg aagcataaag ataggcggga tagcaataag tgaatattct gacgaagcct
     5881 taattaaagc catttccttt gtttttcaag attcaaaatt attcaagaag agcatttatg
     5941 ataatgtagc tttagctaat aaagatgcga cgaaagatga cgttatgaga gccttaaaat
     6001 tagcaggatg cgatttaata ttagacaaat tcccagaaag agaaaataca atcataggct
     6061 caaaaggtgt ttatttatcc ggtggagaaa aacaaagaat tgcaattgct agagcaattt
     6121 taaaggattc caaaattatt attatggatg aagcatcagc atctattgac ccagataacg
     6181 agtttgaatt gcaaaaagct tttaaaaatc ttatgaagga taaaacagtt atcatgattg
     6241 cacacaggct atctacaatt aaagaccttg atgaaattat tgtcatggat agtggaaaaa
     6301 ttatagaaag agggtctgac aaagaattaa tgtcaaaaga tacaaggtat aagagcctgc
     6361 aagagatgtt taacagtgcg aatgaatgga gggtttcaaa tgaaagagtt ttataaaaaa
     6421 agatttgctc ttacagatgg aggagcaaga aatttaagta aagcaacact ggcttcattt
     6481 ttcgtttatt gtataaacat gcttcctgcc atattactta tgatttttgc tcaggaagtt
     6541 ttggaaaata tgggcaaaag caatggcttt tatatagtat tctcagtttt gactttgata
     6601 gcaatgtata ttttgctttc tatcgaatac gataaattat ataacacaac ctatcaagaa
     6661 agtgcagatt taagaataag gacagcggag aatttatcaa aattacctct atcttacttt
     6721 tctaaacatg acatttccga catttcacaa acaatcatgg ctgatattga aggcatagag
     6781 catgcaatga gccactcaat accaaaggtg ggcggcatgg tactgttttt cccattaata
     6841 tctgtaatga tgctagcggg caatgtcaag atgggtttag ctgtaattat tccatctatt
     6901 ttaagcttta tatttatacc tttatctaaa aaatatcagg ttaatggaca gaatagatat
     6961 tatgatgtct taagaaaaaa ctcagaaagc tttcaagaaa atatcgaaat gcaaatggag
     7021 attaaagcat ataatttatc gaaggatatt aaagatgact tatataaaaa aatggaagat
     7081 agtgagagag tacacttaaa ggcggaagta actacaattt taactttgtc tatatcttca
     7141 atatttagct ttatatctct tgctgttgtg atatttgtcg gcgtaaatct aattattaat
     7201 aaagagataa attctctcta ccttatagga tatttactag ctgctatgaa gataaaagac
     7261 tctttagatg catctaaaga gggcttgatg gaaatatttt atttatcgcc caaaatagaa
     7321 agattaaaag aaattcaaaa tcaagattta caagaaggcg atgactatag cttaaaaaaa
     7381 tttgatattg atctaaaaga tgttgagttt gcctacaata aagacgcaaa agttttaaat
     7441 ggtgtaagtt ttaaagctaa gcagggagag gtcactgctt tggtaggtgc aagtggctgc
     7501 ggtaaaacaa ctatcttgaa acttatatca agactttatg attatgacaa gggacaaatc
     7561 ttaatcgatg gcaaagatat aaaagaaata tcaacagaat ctctttttga taaggtctct
     7621 atagttttcc aagatgtggt tctctttaat caaagcgtta tggaaaatat tagaatcgga
     7681 aagcaagatg caagtgacga agaggttaaa agagcagcaa aacttgcaaa ttgcacagat
     7741 tttatagaaa aaatggataa aggtttcgat acagttattg gtgagaacgg agctgagcta
     7801 tcaggaggag aaagacaaag attatcaata gccagagcct tcttaaaaga tgcgccgata
     7861 ttgatcttag atgagataac agcaagcctt gatgttaaca acgagaaaaa gattcaagag
     7921 tctttaaata atttagttaa agataaaact gttgtaatca tttcacatag aatgaaatcc
     7981 atagaaaatg cagacaagat agtagttctt caaaacggaa gagtagaaag cgaaggtaag
     8041 catgaagagc ttttacaaaa atcaaaaatt tacaaaaatt taatagaaaa gacaaaaatg
     8101 gcagaagaat ttatttatta ggaggactac aatggataat aaaaaattaa aagtaaaaga
     8161 tttagtaagt atcggtgttt ttggcgtaat ttattttgcc ttcatgtttg gagttggtat
     8221 gatgggcttg attccaatat tgttcttaat atacccgaca gtattagcca tagttgcagg
     8281 aactgttgtt atgttattta tggctaaggt tcaaaagcca tgggcactat ttatatttgg
     8341 tatgatatca ccacttgtga tgtttgcagc tggtcatacc tacatagttg tggttttatc
     8401 acttatagta atgataatag cagaattaat tagaaagatt ggtaattata attcatttaa
     8461 atacaatatg ctttcttatg caatcttcag cacatggata tgtagctctt taatgcaaat
     8521 gcttttagca aaagaaaaat atatggagtg gtctttgatg acgatgggaa aagattatgt
     8581 tgatgtatta gaaaagttaa taacttatcc tcacatggct ttagtagcct taggtgcttt
     8641 cttaggagga attcttggag catatatagg caaggctcta ttgaaaaaac acttttcaaa
     8701 tggattatat tgtgtgggat actttactcc ttgcctaatt ttatggtgtt atctgaatta
     8761 aaccctatag ttaagatgtt tttgagtata cctattgtta ttagaatgtt tattttacca
     8821 tttatggcag caagctttat gataaagacc tcggatgtag gcgcaataat ttcatcgatg
     8881 gataagctta agatttcaaa gaatgtatcc atacctattg cggttatgtt tagattcttc
     8941 ccatctttta aggaggagaa gaaaaacatc aaaatggcta tgagagtaag agggataaat
     9001 tttaaaaacc cagtcaaata tcttgaatat gtttctgtgc cactactcat tatatcatct
     9061 aatatatcag atgacattgc aaaagcggca gaaacaaagg caatagaaaa tccaattgcc
     9121 aagaccagat acattcgcgt aaagatacag ctaattgatt ttgtttatgt tttagcggtt
     9181 gctggactta ttgtgggagg attaatatgg ttgaaataaa aaatttaagt cttgattatg
     9241 gtgaagagca tatattagat gatatatcac tatccatagc cgagggagag tgcgtgctat
     9301 ttacaggaaa aagtggaaat ggtaagtcat ctttaataaa ttcaatcaat ggactagctg
     9361 taaggtatga caacgcaaag acaaagggcg aaataattat tgatggtaag aatataaaaa
     9421 atttggaact ttatcaaatc tcaatgcttg tttcaactgt ttttcaaaat cctaagacat
     9481 atttttttaa tgtcaatacg acattagaat tattatttta tttggaaaat atcggtcttg
     9541 caagagaaga gatggacagg cgtttgaagg atatgcttga gatattcccg ataaaaaatc
     9601 ttttaaacag aaatatattt aatctatccg gcggtgaaaa acaaattctt tgcattgcag
     9661 cttcttatat agcaggtaca aagattatag ttatggatga gccttcatcg aatttagata
     9721 ttaaaagcat aagtgttttg gcaaagatgc taaagatatt aaaagagaaa ggcataagca
     9781 taattgttgc agagcataga atttattatt tgatggacat agttgaccgt gtatttttaa
     9841 tagataaagg aaagcttaaa aaaacttata ctagaagtga atttttaaag ctagataaaa
     9901 atgaattaaa tgctttaagt ttaagagata aagaattaag taaattaaaa gttccttatt
     9961 taaaagaagg tggagagtat cagataaaaa atcttagcta caaatttact gatgatgagt
    10021 gtttaagctt aaaagatatt tcgttcaagc ttgggaaaat ttatggcata ataggatcca
    10081 acggacgagg aaaatcaacg cttttaagat gtttaatagg tcttgagaaa aaatcaaaag
    10141 aagaaattta ttttaaggga gagaagctat ctaaaaaaga aagactcaaa aactcttcac
    10201 ttgttatgca agatgtaaat catcaattat tcacagatga agtattcaac gagcttagat
    10261 taggagtaaa gaattttgat gaagaaaagg cgaaaatcat cttaaaagat ttaggcctgg
    10321 acgaatttat tgaaaggcat ccgatgagtt tatcaggagg gcaaaagcaa aggcttgcaa
    10381 tagcatctgt tatgtgcaag aattctccat ttgtcttttt tgacgaacct tcaagtggta
    10441 tggattattc caatatgata aaaatatctg aactgattaa taagtataaa accatggata
    10501 aaataatttt tattgtttcc catgatatag aatttttaaa tgaagtggca gatgaaattt
    10561 ttgaattgta aaatagagtc tgttaaacat gtctatagaa ctagtaaatt gtctaaaaat
    10621 ttaaaagata ctaacacata ttgatattta ttagaaaatt aacttcagga tttttacagt
    10681 atttataaac tttataatat gtatttatag tattaataat ttccatatct ttagggaaat
    10741 tctttattta cttaccataa ttaaagagat gagagataaa tatcggcagt cttcggactg
    10801 cctttatttt tttacttaat ttaatgcagt aaatcatacg attgaaagga atctgcttta
    10861 tatgctataa ttaggtggtt aatctataca tttagaaagg taaaatatag aattggagaa
    10921 tgatatggga ttttcatata ataaattgta accgcccaat aacgaagtct attgaaaaat
    10981 ctccagacta gagaactcac ggatagttcc taatctggag atttcttatt tgcacttttc
    11041 ttgtacaact ttagtccatg gtaaataagc ctctaaaact tctttgttta cgagagtttc
    11101 ctcgtttgga agacattcta gaagatagga tagatatttc tcactattta gttgatgacg
    11161 tttagctgtt tccaacaaac tcataataa
//
LOCUS       DAVHKZ010000053        11027 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000053 DAVHKZ010000000
VERSION     DAVHKZ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11027
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.053"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            180..1340
                     /locus_tag="VVO74_001955"
     CDS             180..1340
                     /locus_tag="VVO74_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU5695938.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATILVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEY"
     gene            1462..2499
                     /locus_tag="VVO74_001956"
     CDS             1462..2499
                     /locus_tag="VVO74_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEU5695939.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSITPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            2706..3560
                     /locus_tag="VVO74_001957"
     CDS             2706..3560
                     /locus_tag="VVO74_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU5695940.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKEELLTIVQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            3710..3967
                     /locus_tag="VVO74_001958"
     CDS             3710..3967
                     /locus_tag="VVO74_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEU5695941.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(4135..4263)
                     /locus_tag="VVO74_001959"
     CDS             complement(4135..4263)
                     /locus_tag="VVO74_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
                     /protein_id="HEU5695942.1"
                     /translation="MDRTDEVSNHIYGKVKLMWFEEIFEEYKFLHNKTHITKVLMN"
     gene            complement(4297..4389)
                     /locus_tag="VVO74_001960"
                     /pseudo
     CDS             complement(4297..4389)
                     /locus_tag="VVO74_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4425..4721)
                     /locus_tag="VVO74_001961"
                     /pseudo
     CDS             complement(4425..4721)
                     /locus_tag="VVO74_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(4711..4872)
                     /locus_tag="VVO74_001962"
     CDS             complement(4711..4872)
                     /locus_tag="VVO74_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEU5695943.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTVQNLDGAYSLYKMA
                     NPEGVEYGN"
     gene            4942..5706
                     /locus_tag="VVO74_001963"
     CDS             4942..5706
                     /locus_tag="VVO74_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU5695944.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            6319..7698
                     /locus_tag="VVO74_001964"
     CDS             6319..7698
                     /locus_tag="VVO74_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU5695945.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIASRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            7712..8377
                     /locus_tag="VVO74_001965"
     CDS             7712..8377
                     /locus_tag="VVO74_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU5695946.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            8491..8586
                     /locus_tag="VVO74_001966"
                     /pseudo
     CDS             8491..8586
                     /locus_tag="VVO74_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            8732..9271
                     /locus_tag="VVO74_001967"
     CDS             8732..9271
                     /locus_tag="VVO74_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU5695947.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            9338..9748
                     /locus_tag="VVO74_001968"
     CDS             9338..9748
                     /locus_tag="VVO74_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU5695948.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            9864..>11027
                     /gene="pavB"
                     /locus_tag="VVO74_001969"
     CDS             9864..>11027
                     /gene="pavB"
                     /locus_tag="VVO74_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEU5695949.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETPGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     SPSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLGENVKTKGQYFYQ"
BASE COUNT         3106 a         2098 c         2528 g         3295 t
ORIGIN      
        1 ttatccggca acctcaaagc agtgctttga gcagcctgcg gctagtttcc tacagatttt
       61 agttggaact cgattcaatt catgtgacaa cgtgaaaatc gttagagcat tttatataga
      121 atatacatgg gaatggagct tactcccatt cctatattta atagaaaaag aggaactcaa
      181 tgctacatta tacaaaagaa gacttgctcg aattgggtgc agaaatcact acgcgtgaaa
      241 tctaccaaca gcctgatgta tggagagaag cttttgaatt ttatcaagca aaacgtgaag
      301 aaattgcagc cttcctacaa gaaatcgctg ataaacatga ctatattaag gttatcttga
      361 caggtgctgg gacttctgct tatgtgggag acaccttgct accttacttt aaggaagtct
      421 atgacgaacg caaatggaat ttcaatgcta ttgcgacaac agatatcgtt gccaatccag
      481 caacctattt gaaaaaagat gtggcaacta tccttgtgtc ttttgctcgt agtgggaact
      541 cgcctgaaag tgtggcgact gttgatttgg ccaaatcctt ggtggatgag ctttatcaag
      601 tgacgattac ttgtgcaaca gatggtaaat tggctcttca agctcacggt gatgaccgta
      661 atctcttgct cttgcaacca gctgtctcta atgatgctgg atttgccatg acttctagct
      721 ttacgtctat gatgttgaca gctctcttgg tctttgatcc tacagaattt gctgttaagt
      781 ctgaacgttt tgaagttgta tctagtcttg cccgtaaagt tttagacaag gcagaagatg
      841 tcaaagagct cgttgattta gactttaacc gtgtcatcta tctaggcgct ggtcctttct
      901 ttggacttgc tcatgaagct cagctcaaga ttttggaatt aactgctggt caagttgcga
      961 ccatgtatga aagcccagtt ggcttccgtc acggtccaaa atctcttatc aacgacaata
     1021 cagttgtttt ggtctttggt acaacgacag actacactcg taagtacgac ttggacttgg
     1081 ttcgtgaagt tgctggtgac cagattgctc gtcgtgttgt gcttttgagt gatcaagctt
     1141 ttggtcttga aaatgtcaaa gaagtggccc ttggttgtgg cggtgtcttg aatgatattt
     1201 accgtgtctt cccttacatc gtttatgccc aactctttgc cctattgact tcactcaagg
     1261 tagaaaataa accagataca ccgtctccta caggtacagt aaaccgtgta gtacaaggtg
     1321 tcataattca cgaatattaa aagtaagaca gtgtttatga attcttgaca agaggatttg
     1381 taaattatca gataaaccat agattgtcag tacgctttct atggtttgtt tgcttgagag
     1441 aaatagtaaa aggagaacag aatgaaagca tacacagagc gtgtatttgg aaatgttgag
     1501 ggcgaggatg tcttggccta tcgatttgag acagacggtg gctaccaact tgaggttatg
     1561 acttatggcg cgaccatctt gcgctatgtc gcacctgaca aggctggaaa ttttgccaat
     1621 gttatcttgg gatttgatga ctttgatagt tatgtaggca atagtcccaa gcatggagca
     1681 agtgtaggtc ctgtagcggg tcgtattgca ggtgcgacct ttgagctcaa tggtaagacc
     1741 tatgaccttg aggttaataa tgctagcaac tgtaatcaca gtggttcaac tggttgggat
     1801 tccagcttgt ttgaagttga agaagtaagc gatcatggct tgactctcta cacagaacgt
     1861 acagatggga caggagggtt ccctggaaat ctcaagattt ggatcagtta tcacttggaa
     1921 gaaactggtg cctatgaaat tagctacaag gtaacgaccg atcaggatac gctggtcaat
     1981 ccaaccaacc acagctattt caacttgtct ggtgatttca cgcagacgat tgaccgtcat
     2041 gtcttccaac taaacacaga gggcatttac tcaatcactc ctgacggtgt tcctgccaaa
     2101 actccagaag ccaaccgtga tgtggtcaaa cacatctaca atggtacctt gttgaaggat
     2161 atctttgcag aagaagatga gcaaatccag ctggcatcag gtttggatca cccatttgcc
     2221 cttcctgtag gccatgacaa tgctggattc ctttatgacc aaaattcagg tcgcttcctg
     2281 cttttcaaga cagaagctcc ttgctttgtg gtctacacag caaactttgt ggatgaaagt
     2341 gtcatcatag gaggtcagcc aatgctacag cacaatggga ttgctcttga agcgcaagct
     2401 ttaccagatg ccattcacag tgaccttaaa ggccaagtca ttcttaaagc tggtcaaacc
     2461 ttcaccagta agacacgtta tgaacttgtt gtgaaataaa aaagctggtc aaaaagtctt
     2521 taaaattaaa ataacgcata ttgtcaggtg atgaaaagtt tgatactatg cgttttatta
     2581 tgaaatgatt tactttatct tatcctgaaa tggtgttatt tttgagttat ctggcttgac
     2641 tttcttgatg gaaattatat aatagttgta ataacaataa ttacaacgag aaaagaggac
     2701 catttatgac ctatgaatac aagagtcaca tttatttggc agagacagtt ttaaatgtaa
     2761 aggatttggc cagtcaaaca gccttttatc agcaagttat tggtttagaa atcttatctc
     2821 aaactgagac agagtccatt ctaggccttg gtggaaaagt cttggtacag ctgattcaag
     2881 cacaagagag cggagaagtg agggaacatt atggtcttta ccatttggcc attctcttgc
     2941 ccacacgcaa ggctttggct gatgtcttga aacacctgac agatttacag attcctcttg
     3001 tcggcggtgc agaccatggt tacagtgaag ctatttactt ggaagatttg gagggaaatg
     3061 gcattgaact ctatcgagat aagccagttt ccacatggga tattcgagaa gatggacgca
     3121 ttatcggagt gacggaggct cttgcggcgc aggacattta tgagttgggg gaaagagtag
     3181 agccctttat cctggcagaa ggtacaagaa tggggcatat tcatctttcc gtcaaggata
     3241 gtcgaaagtc cagccagttt tatcaaaagg tgttagggct agaggataaa ttcagtgtgc
     3301 ctagcgctag ttggattgcg gctggagatt accatcatca tttagcagtt aacgaatggg
     3361 gaggaaaagg tctggcttcg cgtaagcaag gcttaccagg tttagcctac tatgtcatcg
     3421 aagtcgcaca taaagaagaa ctgttaacga ttgtccaacg agcacaagaa gttgacgcac
     3481 caatcaaatg gatgacatcg agccaattgg aaatcacaga ctcagatggc atcgtgaccc
     3541 gtattcgttt agcaaggtaa aattaggaat ttctaataag ttataagtat tgctagtttg
     3601 ctttttgaac ggtctttggt aacagaactg cgtgagctgg atgggtgaga attttgacaa
     3661 agaagctgat tagagatata atgaagaaaa atcgagcaag gaaaaagaaa tgacaaattc
     3721 aaagtatatt acttgtttga aacgttcaga gggccagttg tgtgggattc aaaagatgat
     3781 tgaaggagat cgtgactgtg ctgatattgt gacgcaactg acagcagtga gatctagtgt
     3841 agagcgcgtg attgagatga taattaccga aaatcttact gaatgtatca atcagccact
     3901 agatgattct gaagctcaaa aggaacgcct agaaaaggct atccgatact tgattaaacg
     3961 gaaataaatg aatgttttga gacgatatgt gcaaaggtct attaactatt agaatagttt
     4021 aatgtgagtc aaaagaagtt gtaaaaaatc tttaaaatta aaaaaacgca tagtatcagg
     4081 tgttgaatgt actgaccccc aaaagttaga ttttttctgt ctaacttttg ggggtcagtt
     4141 cataagaacc ttggtaatat gcgttttatt atgtagaaac ttatactctt cgaaaatctc
     4201 ttcaaaccac atcagcttca ccttgccgta gatatggtta ctgacttcgt cagttctatc
     4261 cacaacctca aaacagtgtt ttgagctgac ttcgtcagtt ccatccacaa ccttaaaaca
     4321 gtgttttgag cagcctgcgg ctaacttcct agtttgcact ttaattttca ttgagtatta
     4381 cttcatcttc tcatgaaatt gagtttttgc ccagctcctc ttgattattc tacttgaccg
     4441 ggccaagtat tcataccacc ttctacgttg gtaacggtga ggccttggga gctgagaaat
     4501 tggcaggtag atgcagagcg gactcctcct tgacaaataa catagtattc atggtcaggt
     4561 ttgagttctt tgtagccttg ctctaaggta cttaatggaa gatttttggc acctggtgca
     4621 tgtcctgctt ggaattcatg tgcttcacgg acatcgataa gttctagatt ttcattttag
     4681 tattttccat aaaagtcagc catgctgata ctagtttcca tattctactc cttctgggtt
     4741 agccattttg tatagtgaat aagcgccgtc aaggttttgg acggtaaatc ctgcttgctt
     4801 gaggataggc tctgcgatat agctgcgcaa accactgtgg cagctgacga tgtaggcttg
     4861 ttttttgtcc agttcatcag cttcctcctt gacactttgt cagtttttga tacaatagta
     4921 caaaattaga ggaggtgggc tatgattcag aaacatgcga ttcccatttt agagtttgat
     4981 gataatcctc aggcggttat catgcccaat cacgaggggt tggatttgca gttgccaaag
     5041 aagtgtgtct atgctttttt aggtgaggag attgaccgct atgcgaggga agtaggggcg
     5101 aactgtgttg gcgaattcgt ttctgctacc aagacctatc cagtctatgt catcaactac
     5161 aagggtgagg aggtctgtct ggctcaggct cctgttggct ccgctccagc agcccagttt
     5221 atggattggt tgattggcta tggtgtggag cagattatct ctactgggac ctgtggtgtc
     5281 ctagctgata tagaggaaaa tgcctttcta gtccctgttc gcgctttgcg agatgaggga
     5341 gccagttacc actatgtggc accttgtcgt tatatggaaa tgcagccaga ggctattgct
     5401 gctattgagg aagttttgga agacagaggg attccttatg aagaagtcat gacctggacg
     5461 acagacggtt tttaccgaga aacggctgaa aaggtggctt atcgtaagga agaaggctgt
     5521 gctgttgtgg agatggagtg ttctgctctt gcggcagtag ctcaattgcg tggggttctc
     5581 tggggtgaat tgttgttcac agcagattct ctagcggact tggaccagta cgacagtcgt
     5641 gactggggct cggaagcttt taataaggcg ctagaactga gtttagcaag tgttcaccac
     5701 ctttagttgt acaggcaaag gatttgtttt atcataaaat gtctagctca tacttttcaa
     5761 aaatatgttt aaacgaggtc accttcctct tgtcctaggc atgttgaggt tgggaaaaat
     5821 ctttaaaatc agaaaaacgt atcatatcag gtgatgaaaa ttttgatact atgcgtttta
     5881 tgttggtaag atttagagtg agatgaaatg atactcttcg aaaatctctt caaaccaggt
     5941 cagcttcacc ttgccgtagg tatatgttac tgacttcgtc agtcttatcc ggcaacctca
     6001 aaacggtgtt ttgagctgac ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag
     6061 caacctgtga ctagctttct aagcgatgcc ttggttctca ttgcctataa tcaaaaagag
     6121 aaattttctc ctgaaaagca tatagagtag ctggcgttaa aagctcctgt cttgcttttt
     6181 tgacctatag tcacatctat caagtattgt tcttgcctaa gctatcaata aaaaggtggc
     6241 attttttagg cttggtgtta gtgaattttg ccttatccta tctaagtcat ttcgagcttt
     6301 ttatggtaca atggaaacat gttattcaaa ttatctaagg aaaaaataga gctaggctta
     6361 tctcgtttat cgccagcccg tcgtattttt ttgagttttg ccttggtcat tttactaggc
     6421 tctcttcttt tgagcttgcc ctttgtccaa gttgaaagct cacgagcgac ttattttgat
     6481 catcttttca ctgctgtctc tgcagtctgt gtgacaggtc tctcaaccct tccagtagct
     6541 cacacctata atatctgggg ccaaataatc tgtttgctct tgattcagat cggtggtcta
     6601 gggctcatga cttttattgg ggttttctat atccagagca agcaaaagct tagtcttcgt
     6661 agccgtgcaa ctattcagga tagttttagt tatggagaaa ctcgatcttt gagaaagttt
     6721 gtctattcta tttttctcac gacctttttg gttgagagct tgggagctat tttgcttagt
     6781 tttcgcctta ttcctcaact tggctgggga cgtggtcttt ttagttccat ttttctagcg
     6841 atctcagcct tctgtaatgc cggttttgat aatttaggga gcaccagttt atttgctttt
     6901 cagaccgatt tactggtcaa tctggtgatt gcaggcttga ttattacagg cggccttggt
     6961 tttatggtct ggtttgattt ggctggtcat gtaggaagaa agaaaaaagg acgtctgcac
     7021 tttcatacga agcttgtact attgttgact ataggtttgt tgttatttgg aacggcaact
     7081 actctctttc ttgagtggaa caatgctgga acgattggca atctccctgt tgccgataag
     7141 gttttagtta gcttttttca aacagtgacg atgcgaacag ctggcttttc tacgatagat
     7201 tatactcagg ctcatcctgt gactcttttg atttatatct tacagatgtt tctaggtggg
     7261 gcacctggag gaacagctgg gggactcaag attacgacat tttttgtcct cttggtcttt
     7321 gcacgaagtg agcttctagg cttgcctcat gccaatgttg cgagacgaac gattgcgtcg
     7381 cgaacggttc aaaaatcctt tagtgtcttt attatctttt tgatgagctt cttgatagga
     7441 ttgattctgc tagggataac agccaaaggc aatcctccct ttatccacct catatttgaa
     7501 accatttcag ctcttagtac agttggtgta acggcaaatc tgactcctga ccttgggaaa
     7561 ttggctctca gtgttatcat gccacttatg tttatgggac gaattggtcc cttgaccttg
     7621 tttgttagct tggcagatta ccatccagaa aagaaagata tgattcacta tatgaaagca
     7681 gatattagta ttggttaaga aaggaaagag catgtcagat cgtacgattg gaattttggg
     7741 cttgggaatt tttgggagca gtgtcctagc tgccctagcc aagcaggata tgaatattat
     7801 cgctattgat gaccacgcag agcgcatcaa tcagtttgag ccagttttgg cgcgtggagt
     7861 gattggtgac atcacagatg aagaattatt gagatcagca gggattgata cctgcgatac
     7921 cgttgtagtc gcgacaggtg aaaatctgga gtcgagtgtg cttgcggtta tgcactgtaa
     7981 gagtttgggg gtaccgactg ttattgctaa ggtcaaaagt cagaccgcta agaaagtgct
     8041 agaaaagatt ggagctgact cggttatctc gccagagtat gaaatggggc agtctctagc
     8101 acagaccatt cttttccata atagtgttga tgtctttcag ttggataaaa atgtgtctat
     8161 cgtggagatg aaaattcctc agtcttgggc aggtcaaagt ctgagtaaat tagacctccg
     8221 tggcaaatac aatctgaata ttttgggttt ccgagagcag gaaaattccc cattggatgt
     8281 tgaatttgga ccagatgacc tcttgaaagc agatacctat attttggcag tcatcaacaa
     8341 ccagtatttg gataccctag tagcattgaa ttcgtaaaga gggatgaccc ctcttttttg
     8401 atgcccaaga tggcaaatag agacagaagc cccttgtctt ctagtaaaag ttcttcaaag
     8461 gctggacttt atggtaaaat agaaggaagt gacaagagag agtaatactc aatgaaaatc
     8521 aaagatcaaa ctaggaaact agctgcgggc tgctcaaaac actgttttga ggttgtggat
     8581 agaactgacg aagtcagctc aaaacactgt tttgaggttg cagatagaac tgacgaagtc
     8641 agtaacatct atacggcaag gcgacgttga cgcggtttga agagattttc gaagagtata
     8701 agaaaaaatc agtcccctaa aggagcagat tatgaagtta ttgtctatcg ccatttctag
     8761 ctataatgca gcagcctatc ttcattactg tgtggagtcg ctagtgattg gtggtgagca
     8821 agttgggatt ttgattatca atgacgggtc tcaggatcag actcaggaaa tcgctgagtg
     8881 tttagctagc aagtatccta atatcgttag agccatctat caggaaaata aatgccatgg
     8941 cggtgcggtc aatcgtggct tggcagaggc ttctgggcgc tattttaaag tagttgacag
     9001 tgatgactgg gtggatcctc gtgcctactt gaaaattctt gaaaccttgc aggaacttga
     9061 gagcaaaggt caagaggtgg atgtctttgt gaccaatttt gtctatgaaa aggaagggca
     9121 gtctcgtaag aagagtatga gttacgattc agtcttgcct gttcggcaga tttttggctg
     9181 ggaccaggtc ggaaatttct ccaaaggcca gtataccatg atgcactcgc tgatttatcg
     9241 gacagatttg ttgcgtgcta gccagttcta actgcctgaa catacttttt atgtcgataa
     9301 tctctttgtc tttacgcccc ttcagcaggt caagaccatg tactatctgc ctgtcgattt
     9361 ctatcgttat ttgattgggc gtgaggacca gtctgtcaat gagcaagtga tgattaagtg
     9421 cattgaccag caactcaagg tcaatcgact cttgatagac caacttgatt tgtcccaagt
     9481 gagtcatccc aaaatgcgag aatatctgct gaatcatatt gaactcacga cggtgatttc
     9541 cagtaccctg ctcaaccgat ctggaacagc ggagcatctg gcaaaaaaac gccaattgtg
     9601 gacctatatt cagcagaaaa atccagaagt ctttcaggct attcgtaaga ccatgttgag
     9661 ccgtttgacc aaacattctg tcttgccaga tcgcaaactg tccaatgtcg tctatcaaat
     9721 caccaaatct gtttatggat ttaattaata taagtgtttt ataagaggga tttaagaaaa
     9781 attttaactt tttcttagtc ctttttaatt tcaggagatt atactagagt catcaaataa
     9841 agaaagactc taaggagaat cctatgaaat tcaatccaaa tcaaagatat actcgttggt
     9901 ctattcgccg tctcagtgtc ggtgttgcct cagttgttgt ggctagtggc ttctttgtcc
     9961 tagttggtca gccaagttct gtacgtgccg atgggctcaa tccaacccca ggtcaagtct
    10021 tacctgaaga gacaccggga acgaaagagg gtgacttatc agaaaaacca ggagacaccg
    10081 ttctcactca agcgaaacct gagggcgtta ctggaaatac gaattcactt ccgacaccta
    10141 cagaaagaac tgaagtgagc gaggaaacaa gcccttctag tctggataca ctttttgaaa
    10201 aagatgaaga agctcaaaaa aatccagagc taacagatgt cttaaaagaa actgtagata
    10261 cagctgatgt ggatgggaca caagcaagtc cagcagaaac tactcctgaa caagtaaaag
    10321 gtggagtgaa agaaaataca aaagacagca tcgatgttcc tgctgcttat cttgaaaaag
    10381 ctgaagggaa aggtcctttc actgccggtg taaaccaagt aattccttat gaactattcg
    10441 ctggtgatgg tatgttaact cgtctattac taaaagcttc ggataatgct ccttggtctg
    10501 acaatggtac tgctaaaaat cctgctttac ctcctcttga aggattaaca aaagggaaat
    10561 acttctatga agtagactta aatggcaata ctgttggtaa acaaggtcaa gctttaattg
    10621 atcaacttcg cgctaatggt actcaaactt ataaagctac tgttaaagtt tacggaaata
    10681 aagacggtaa agctgacttg actaatctag ttgctactaa aaatgtagac atcaacatca
    10741 atggattagt tgctaaagaa acagttcaaa aagccgttgc agacaacgtt aaagacagta
    10801 tcgatgttcc agcagcctac ctagaaaaag ccaagggtga aggtccattc acagcaggtg
    10861 tcaaccatgt gattccatac gaactcttcg caggtgatgg catgttgact cgtctcttgc
    10921 tcaaggcatc tgacaaggca ccatggtcag ataacggcga cgctaaaaac ccagccctat
    10981 ctccactagg cgaaaacgtg aagaccaaag gtcaatactt ctatcaa
//
LOCUS       DAVHKZ010000054        10758 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000054 DAVHKZ010000000
VERSION     DAVHKZ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10758
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.054"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(34..270)
                     /locus_tag="VVO74_001970"
     CDS             complement(34..270)
                     /locus_tag="VVO74_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU5695950.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(338..1258)
                     /locus_tag="VVO74_001971"
     CDS             complement(338..1258)
                     /locus_tag="VVO74_001971"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU5695951.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDSDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            1448..1851
                     /locus_tag="VVO74_001972"
                     /pseudo
     CDS             1448..1851
                     /locus_tag="VVO74_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2067..2648
                     /locus_tag="VVO74_001973"
     CDS             2067..2648
                     /locus_tag="VVO74_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU5695952.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            2645..3922
                     /locus_tag="VVO74_001974"
     CDS             2645..3922
                     /locus_tag="VVO74_001974"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU5695953.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            3940..4602
                     /gene="deoC"
                     /locus_tag="VVO74_001975"
     CDS             3940..4602
                     /gene="deoC"
                     /locus_tag="VVO74_001975"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU5695954.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASADKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            4589..4978
                     /locus_tag="VVO74_001976"
     CDS             4589..4978
                     /locus_tag="VVO74_001976"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU5695955.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            5069..6121
                     /locus_tag="VVO74_001977"
     CDS             5069..6121
                     /locus_tag="VVO74_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU5695956.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            6265..7800
                     /locus_tag="VVO74_001978"
     CDS             6265..7800
                     /locus_tag="VVO74_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695957.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENITLQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            7793..8851
                     /locus_tag="VVO74_001979"
     CDS             7793..8851
                     /locus_tag="VVO74_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5695958.1"
                     /translation="MFKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            8854..9810
                     /locus_tag="VVO74_001980"
     CDS             8854..9810
                     /locus_tag="VVO74_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5695959.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            9894..10758
                     /locus_tag="VVO74_001981"
                     /pseudo
     CDS             9894..10758
                     /locus_tag="VVO74_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         3163 a         1885 c         2454 g         3256 t
ORIGIN      
        1 acttcaaccc actacagttg acaaagagcc ttcttattta gcaagtttag ctgaaagacg
       61 agctttatcg cggcttgctt tgtttttgtg aatcaaacct ttagtttctg ctttatcgat
      121 agctgagcta gcagcacgga aaagttcttc agatgggttt gcttcgaaag cttttatagc
      181 agtacgcata gctgattttt gagctgagtt cttttcgttt tgtttaacgt tcaattcagc
      241 gcgtttgata gctgatttaa tgtttgccaa tgttcttacc tccatattta ctaactatac
      301 cattatatat gaaaacttac gttttgacaa gggaaaatta tttttttaag taaatttcat
      361 cgatttcatg gttcttgctt ttatgaagaa tcacttctgc acgatttctg gttggttcaa
      421 tataattttg tagatttgtg agattgatac tggtccagac ctgatgggca aaggcttcca
      481 cttccccaat cggcatctga gtaaaacgat aatagtagct atcagagtcg ttttgggcta
      541 gactcagcat tttcaagaaa cggtccagat accaactttc aatatcatcc actccagcat
      601 ctacatagat ggaaaagtca aagaagtcag tgatatagag acgatcgttt tgtggatttt
      661 gaaagacatt gattccctca acaattacaa aatcagcagc tttgacactt tgtttctctt
      721 cgggtacgat gtcgtaaact tcatgagaat agacaggaat atctacatct tgtccatttt
      781 tgatgcggtc caagaagttg agaagagctt ccatatcata gctttcagga aatcctttac
      841 gatttaaaat cccctgctca atcaaggttt gattgggata gagaaaacca tcagttgtaa
      901 ccaactcaac cgtagcatct gtaaacgtac gggacagtag gatttgaagt aggcgactgg
      961 ttgtggattt tccaacggca acactcccag aaaccccaat aataaaaggt tgagatttac
     1021 tttcacgttg gaggaaaatt ccttttgaaa aggctaaatc ttccttagtt cgcttgtaaa
     1081 tctgaatcag atgagccaag gggagataga tatctgtaac gtcttggaga ctgatttggt
     1141 cattaaaact cttgatagat tccaattctt cttctgtcaa aggaggtgtt gtctttcgat
     1201 gtaaagattg ccaagtctgg cggctgattt tttcaaaatg taaaaattcg ttggtcattt
     1261 gttttcccct agatattttg tctatcatac cataaaaagc taaaaaaata aagcggtttc
     1321 ttgaatgtgg taagtcaatg gtatatagta taagtgatca atttattgat gaaataggag
     1381 atagattcta ctgatttata agcttataaa gggggctttt tagttcacaa cttataggag
     1441 gtgtactatg aaaatcttaa aacgttacat attggaactc tgttttattt taagttttgc
     1501 tttacctttt ataaaaggag ccaatgcaga taatggtaga tgctttgtgg aaacctatta
     1561 cggttttact tttttgatgg aacatgctat tgtaacagct gtctttatct gttcgttctt
     1621 aattgctttc ttactaaaaa acgatgggcg aaatggattg ctgcgggtag ttattgcttt
     1681 ttagtcctac ggattgcgac agagggttat ttcttccaca tgtcactaga agatttgata
     1741 cgactttgga caagtttgga aatcctgaca caaacgtatc agttgggctt ttatctaaac
     1801 attttgttag gaattttgtt gataataaag tattttaagg ttaagcaata gaaataataa
     1861 tctgcctgat tatagatgat aaactttttg tttttatctg gactgtgata tttatagttc
     1921 taaatggttt attatttata agtgttgaaa gagattgaag aaaatggctt cgtgacttgc
     1981 tttcttcggt ctttttcgtt ttattatcaa tttgtaaacg atttacaatt tgagtcaaat
     2041 tatggtaaaa tagtgtcatg agtaaaatgt actatgcaga aaatcctgac gctgctcacg
     2101 acattcatga gttgagagtg gacttgttgg gagaaaaaat gacttttttg acagatgcgg
     2161 gtgtttttag caagaaaatg gttgactttg gaagtcaact cttgctcaag tgtctggatg
     2221 tcaaccaagg agagacagtc ctagatgtag gctgtggcta tggtccatta ggtttgtcct
     2281 tggtcaaggt ttacggagtt caggcgacca tggttgatat taacactcgt gccctggatt
     2341 tagctcagag aaatgctgaa aaaaataatg caaaagcgac gatatttcaa tctaatattt
     2401 atgcaagagt tcaagggcga tttgaccatg tcatttccaa tcctcctatc cgtgcgggca
     2461 agcaagtcgt tcatgaaatc atcgagaaaa gtaaagattt cttggaaatt ggtggagatt
     2521 tgaccatcgt catccagaaa aaacaaggag ctccaagtgc caagtctaag atggaagatg
     2581 tgtttggcaa ttgtgaaatc cttaaaaaag acaagggata ctatatcctt agaagtgtga
     2641 aagaatgaga gcagttgatt taatccaaaa aaaacgagac ggtcaagaac tgacttcaag
     2701 tgaaattgaa tggctgatag aaggctatgt atcaggaact gttcctgatt atcagatgtc
     2761 tgcctttgct atggctgttt attttaaagg aatgacgact cgagaaatct ctgatttaac
     2821 gatgaatatg gttaagactg ggcaagagtt tgacctgtca gccattgatg gtgtgaaagt
     2881 tgacaagcat tctactggtg gtgtcggcga taaggtaacc ttgattttag ctcctcttgt
     2941 tgctagcttc ggtgtgcctg tagcaaaaat gagtggtcgt ggtcttggcc atacaggcgg
     3001 aacaattgat aaattggagt ccattaaggg ctatcaagta gaacgtagtc aagaggattt
     3061 tattcgtcag gttcaggata ttggagtatc tgtcattggg caatcagacc agctggtcaa
     3121 agcagataag cttctctatg cccttcgtga tgtgaccgca actgtcgaca cgattccttt
     3181 gattgcgagt tcggtgatga gcaagaaaat tgcggcaggg gcggatgcta ttttgctaga
     3241 cgtgactgtc ggtgagggtg ccttcatgaa gacggttgat gaggcgcgtg agttggctca
     3301 aactatggta gatcttggta aggttgttgg acggaagaca gtagcagtga ttacggatat
     3361 gagccagcct ttgggacgag cgattggaaa tcgtctggaa atccttgaag cattggagat
     3421 tttgcaaggt caaggacgtc aggatattac ccactttatt tgtgaattgg ctcaaattat
     3481 gcttggtttg gcaaatgtta acaagactgt tgaagaagtt cgccaacatc ttgagaatgg
     3541 tcaagcactg gctaagtttg aggaaatggt gcaagcccaa ggtggagact tggaagacct
     3601 ctatcgtcct gtaaatgtag ctcatgtggt ggaaatccct gctcaggaaa cgggtgtcat
     3661 ttcagctctt ccagctatgg actttggtct ttatgccatg aggctgggtg ctggtcgtgc
     3721 agttaagtct gatgccttgg actatgaaac aggaattgtt tttgaaaaga agattggaga
     3781 ctccgttcaa aagggtgaaa ttgttgcaaa agtatacaca aatgaaaaaa ttccacctca
     3841 actagttaca gatttccaaa aatgtgttaa aataagtgat gaagtgaaaa aaatccgtga
     3901 aattgtagaa atcatctcct aaatggaggg aaaaccgaaa tgaaattaaa taaatatata
     3961 gatcatacgc ttttaaaaca agatgcaaag aaaaaacaaa ttgatagttt gttgtctgag
     4021 gctagagagt atgactttgc cagtgtttgc gttaatccga cctgggttga acatgctaaa
     4081 aaaggacttg aaggcacaga tgttaaggtt tgcacagtag taggtttccc tttgggagca
     4141 acaacttcag ccgtgaaagc atttgagaca aaagaagcta tccaaaatgg tgcagatgag
     4201 attgatatgg tgatcaatgt tggagctctc aaatcaggta atttagcctt ggttgagtca
     4261 gatattcgcg cagtagtgga agcaagtgct gataagttag tgaaagtcat tattgaagct
     4321 tgccttctga cagaccaaga aaaaattgtt gtttgccaat tggcccaaaa agctggggct
     4381 gactttgtta aaacatctac tggtttttca actggtggtg ctacgatagc agatgttaca
     4441 ttaatgcgtg aaacagttgg atctgatatg ggagtcaagg ctgctggtgg agctcgttct
     4501 tatgcagatg ctcttgcctt tgtcgaagca ggtgcgaccc gtatcggaac gtcagctggg
     4561 gtagctattt taaaaggaga attggcagat ggcgactact gagttgattg aactggcaat
     4621 tgaaaccagc aaacatgcct atgtccccta ttctcacttt cctatcggag cagttttagt
     4681 agccaaagac ggaaatgttt acacgggagt gaatatcgaa aatgctagct atcctttgac
     4741 caattgcggt gagagaacag ctatttttaa ggctatatct gaaggccaaa gagaattttc
     4801 agaattgatt gtctatggtc aaactgaaaa accgatttca ccatgtggtg cttgtcgcca
     4861 agtaatggtc gaattttttg aacaagattt aaaagtgacc ttagtcgcaa aagataaatc
     4921 gacggtcgag atgacggtcg gggagttact tccatattct tttacagact taaattagtc
     4981 tgagtcgctc tttgagtggc aagggtcttt gtgaccaatc aatccatact tgcaacatcg
     5041 ttgcacatct tatttaggag gttcagtaat gaacaagaaa caatggctag gtcttggcct
     5101 agttgcagtg gcagcagttg gacttgctgc atgtggtaac cgctcttctc gtaacgcagc
     5161 ttcatcttct gatgtgaaga caaaagcagc aatcgtcact gatactggtg gtgttgatga
     5221 caaatcattc aaccaatcag cttgggaagg tttgcaggct tggggtaaag aacacaatct
     5281 ttcaaaagat aacggtttca cttacttcca atcaacaagt gaagctgact acgctaacaa
     5341 cttgcaacaa gcggctggaa gttacaacct aatctttggt gttggttttg cccttcacaa
     5401 tgcagttgaa gaagcagcta aagaacacac tgacttgaac tatgtcttga ttgatgatgt
     5461 gattaaagac caaaagaatg ttgcgagtgt aactttcgct gataatgagt caggttacct
     5521 tgcaggtgtg gctgcagcaa aaacaactaa gacaaaacaa gttggttttg taggtggtat
     5581 cgaatctgaa gttatctctc gttttgaagc aggattcaag gctggtgttg cgtcagtaga
     5641 cccatctatc aaagtccaag ttgactacgc tggttcattt ggtgatgcgg ctaaaggtaa
     5701 aacaattgca gccgcacaat acgcagccgg tgcagatatt gtttaccaag tagctggtgg
     5761 tacaggtgca ggtgtctttg cagaggcaaa atctctcaac gaaagccgtc ctgaaaatga
     5821 aaaagtttgg gttatcggtg ttgaccgtga ccaagaagca gaaggtaaat acacttctaa
     5881 agatggcaaa gaatcaaact ttgttcttgt atctactttg aaacaagttg gtacaactgt
     5941 aaaagatatt tctaacaagg cagaaaaagg agaattccct ggcggtcaag tgatcgttta
     6001 ctcattgaag gataaagggg ttgacttggc agtaacaaac ctttcagaag aaggtaaaaa
     6061 agctgtcgaa gatgcaaaag ctaaaatcct tgatggaagc gtaaaagttc ctgaaaaata
     6121 atggatggaa gtcatttctt aggaagcggc caagggccgc ttttttaaga gttgagacaa
     6181 agtcattttg tctcagtaaa gcttgctact agacaaacta gcaagtttta ttgaaataaa
     6241 ataagactct gaaaggaaga gcacatggca cacgaaaatg tcattgagat gcgtgatatt
     6301 accaaggtgt ttggtggatt tgttgctaac gacaaaatca acttgcacct acgaaaaggt
     6361 gaaattcatg cacttttagg agaaaatggg gctggtaagt ccacgctaat gaacatgtta
     6421 gcagggcttc ttgaaccaac tagtggtgaa atcgcggtca acggtcaagt tgtcaatctc
     6481 gactccccat ctaaagcagc tagcttggga atcgggatgg ttcaccagca ctttatgttg
     6541 gttgaagcct tcacagtggc tgaaaacatc attttaggta gtgaattgac taaaaatggt
     6601 gtgctagata tcgctggagc tagcaaagaa atcaaggctc tttctgaacg ttatggctta
     6661 gctgttgacc cttctgccaa ggtagcagat atctcagttg gagcccaaca acgtgtagaa
     6721 attttaaaaa cactttatcg gggggctgat atccttatct ttgacgaacc aacggctgtt
     6781 ttgactccat cagaaattga tgagttgatg gctattatga aaaatcttgt caaagaagga
     6841 aaatcaatta tcttgattac ccacaaattg gatgaaattc gagcagtttc tgaccgtgtt
     6901 acagttatcc gtcgtgggaa atcaattgaa accgttgaaa ttgcaggggc taccaatgct
     6961 gatttggcgg aaatgatggt aggacgttct gtttccttta aaacagagaa gcaagcctct
     7021 aaaccaaaag aagtggtttt gtctatcaaa gatttggtgg tcaatgaaaa ccgtggtgtt
     7081 ccagctgtta aaaatctgtc cttggatgtt cgtgctggag agattgttgg tattgcgggg
     7141 attgatggaa atggtcagtc tgaactgatt caagccatta caggtcttcg taaggttgaa
     7201 tctggtagca ttgagctaaa aggagattca attgtaggct tgcacccacg tcagattaca
     7261 gaactaagtg ttgggcacgt tccagaagac cgtcaccgtg atggcttgat tttggaaatg
     7321 atgatatctg aaaatattac ccttcaaacc tactataaag aaccacatag taaaaatgga
     7381 attttgaatt attcaaatat tacttcttat gctaaaaagc tgatggaaga gtttgatgtt
     7441 cgcgctgcca gtgaattagt tcctgcagct gcactctcag gaggaaatca acaaaaagca
     7501 attattgctc gtgaaattga tcgagatcct gatctcctta tcgttagcca gccaactcgt
     7561 gggttggatg tcggtgccat tgagtatatc cacaaacgct tgattgaaga gcgtgataat
     7621 ggcaaggctg tccttgttgt cagctttgaa ttggatgaga ttttaaacgt ctcagaccgt
     7681 attgccgtta tccacgatgg taagattcaa ggtattgtat caccagaaac aaccaataaa
     7741 caagaacttg gtgtcttgat ggctggtgga aacttgggaa aggagaagag tgatgtttaa
     7801 aaaattacaa caaatttcgg ttcccttgat ttctgtattt ctaggaattt tactcggagc
     7861 cattgtcatg tggatcttcg gttatgatgc tatttggggc tacgaagaat tgttctatac
     7921 agcctttggc agtctgcgtg ggattggaga aatcttccgt gctatgggtc ctctggtctt
     7981 gattggtctt ggttttgcgg ttgccagtcg agctggtttc tttaacgtcg gacttcctgg
     8041 tcaggctttg gcaggttgga ttctcagtgg ttggtttgcc ctgtcgcatc cagatatgcc
     8101 ccgtcccttg atgattctag caaccatcgt gattgccttg attgctggtg ggattgtcgg
     8161 agcgattcca ggtattctta gggcctatct agggacgtca gaggttattg taaccatcat
     8221 gatgaactac attgtcttgt atgtagggaa tgcctttatc catgctttcc ctaaagactt
     8281 catgcaaagt acagattcga ccattcgtgt tggggctaat gcaacctatc agacaccttg
     8341 gttggctgag ttgactggta actcacggat gaatattggt attttctttg ccatcattgc
     8401 cgttgcagtt atttggttca tgctcaagaa aacaactctt ggttttgaaa tccgtgcagt
     8461 tggtcttaat ccacatgctt cagaatatgc tggtatttct gccaagcgga ctattatcct
     8521 atctatgatt atttcaggtg ctttggcagg tcttggtgga gctgttgaag gtttgggaac
     8581 cttccagaac gtctatgttc aaggttcgtc attagctatc ggatttaacg gaatggcggt
     8641 tagtttgctt gcggccaact caccaattgg tatactcttt gcagccttcc tatttggcgt
     8701 tctccaagtt ggggctcctg gtatgaatgc ggcgcaggta ccatctgagc ttgtcagcat
     8761 tgtaacagcg tctattatct tctttgtcag tgttcattac cttatcgaac gctttgttaa
     8821 accgaaaaaa caagttaaag gaggtaagta aagatgtcta ttataacctt gctccccctc
     8881 ttggtgtctt ctatgctgat ttactcagca cctctcatct ttacaagtat cggtggtgtt
     8941 ttctctgaac gtggtggtgt ggtaaacgtt ggccttgaag gaattatggt tatgggtgcc
     9001 ttttctggag ttgtctttaa ccttgaattt gcagaacaat ttggagcagc aactccatgg
     9061 ctatccttgc ttgtagcagg attggttggt agtgttttct ctatcatcca cgcagcagcg
     9121 acggttcatt tccgtgcaga ccatgttgtc agcggtacgg tattgaactt gatggcgcct
     9181 gccttggctg ttttcttagt taaagttctt tataacaaag gacaaaccga caacctaagt
     9241 caaacttttg gacgctttga tttcccagtc ttggcaaata tcccagtgat tggtgatatc
     9301 ttcttcaagt caactagtct acttggttat ctggcgattg ccttctcatt ccttgcttgg
     9361 tttattctct ttaagactca atttggtctt cgtctccgct ctgtcggtga acatcctcaa
     9421 gcagcggata ccttgggaat caacgtctac aagatgagat atttagggat tattatttca
     9481 ggttttctag gtggaattgg cggagcgatt tatgcgcaat caatctcagt taacttctca
     9541 gtgacaacta ttgttggacc tggatttatc gcccttgctg cgatgatctt tgggaaatgg
     9601 aatccaatcg gtgctatgct ttctagtctc ttctttggac tttcacaaag tttggctgtt
     9661 atcggttctc aattgccgtt cctacaagga gtgccagcgg tttatcttca aattgcacct
     9721 tatgttttga caattcttgt cttagcagcc ttctttggaa aagcagtcgc accaaaagca
     9781 gatggtatca actacatcaa atcaaaataa gcatacaaaa aacgtcagtt caatgactga
     9841 actgcccccc aaaagttaga cagaaaaaat ctaacttttg gggtgttttt attatgaaac
     9901 taacttatga tgataaagtt cagatctatg aacttagaaa acaaggatat agcttagaga
     9961 agctttcaaa taaatttggg ataaacaatt ctaatattag gtacatgatt aaattgattg
    10021 atcgttacgg aatagagttc gtcaaaaaag gaaaaaatcg ttactattct cctgatttaa
    10081 aacaagaaat gattcataaa gtctgacatg aaggctggac taaagataga gtttctcttg
    10141 aatacggtct cccaagtcgt acgatacttc ttaactggct agcacaatac aggaaaaacg
    10201 ggtatactat tgttgagaaa ccaagaggga gagtacctaa aatgggacgt aatccaaaaa
    10261 cgagacctga agagaggaca gaattagaac gtcttcaagc agaaaatgag tacctgagag
    10321 cggagaatgc catcctaaaa aagttaagag aactccgatt gaaggaggaa aaagagaaag
    10381 aagaaagaca gaaattgttc aagaattaat gactgagttt tcgttagatc ttcttctaaa
    10441 agccattaaa ctagctcgtt cgacctacta ctatcacttg aaacagctaa acaaaacaga
    10501 taaggaccaa gagcttaaag ctgaaattca atccatcttt atcgaacaca agggaaatta
    10561 tgcttatcgt cggatttatt tagaactaag aaatcgtggt tatctggtaa atcataaaag
    10621 agttcaacac ttgatgaagt actcaattta caagctaaaa cgcgacagaa acgaaaatat
    10681 tcttctcata aaggagacgt tggcaagaaa gcagagaatc tcattcaagg ccaatttgaa
    10741 ggctctaaaa caatggaa
//
LOCUS       DAVHKZ010000055        10703 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000055 DAVHKZ010000000
VERSION     DAVHKZ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10703
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.055"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            1..609
                     /locus_tag="VVO74_001982"
                     /pseudo
     CDS             1..609
                     /locus_tag="VVO74_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            575..955
                     /locus_tag="VVO74_001983"
     CDS             575..955
                     /locus_tag="VVO74_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU5695960.1"
                     /translation="MRLFCLVLVSIDYINCLSETTDKNWHKSDRVFVTNTGKTVHSSI
                     LSKSLQRANERLKKPIPKHLSPHIFRHTTISILSENKIPLKTITDRVGHSDSEVTTSI
                     YTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1093..2397)
                     /gene="eno"
                     /locus_tag="VVO74_001984"
     CDS             complement(1093..2397)
                     /gene="eno"
                     /locus_tag="VVO74_001984"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU5695961.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2561..3007
                     /locus_tag="VVO74_001985"
     CDS             2561..3007
                     /locus_tag="VVO74_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU5695962.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(3004..4119)
                     /locus_tag="VVO74_001986"
     CDS             complement(3004..4119)
                     /locus_tag="VVO74_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEU5695963.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASDQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(4128..4457)
                     /locus_tag="VVO74_001987"
     CDS             complement(4128..4457)
                     /locus_tag="VVO74_001987"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEU5695964.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4402..4773)
                     /locus_tag="VVO74_001988"
     CDS             complement(4402..4773)
                     /locus_tag="VVO74_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEU5695965.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4832..6265)
                     /gene="glgA"
                     /locus_tag="VVO74_001989"
     CDS             complement(4832..6265)
                     /gene="glgA"
                     /locus_tag="VVO74_001989"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEU5695966.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHIHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWLAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6262..7401)
                     /gene="glgD"
                     /locus_tag="VVO74_001990"
     CDS             complement(6262..7401)
                     /gene="glgD"
                     /locus_tag="VVO74_001990"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEU5695967.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7391..8533)
                     /locus_tag="VVO74_001991"
     CDS             complement(7391..8533)
                     /locus_tag="VVO74_001991"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEU5695968.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8523..10451)
                     /gene="glgB"
                     /locus_tag="VVO74_001992"
     CDS             complement(8523..10451)
                     /gene="glgB"
                     /locus_tag="VVO74_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEU5695969.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPNVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLICIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3258 a         2342 c         1892 g         3211 t
ORIGIN      
        1 tagcttctga atttggctgt catccaacta ccatccacta tacgctcaaa gctatgggct
       61 acactcgaaa aaaagaacca cacctactat gaacaagacc cagaaaaagt agccttattt
      121 cttaagaatt ttaatagttt aaagcaccta gcacctgttt agattgacga aacaggattc
      181 gatacttatt tttatcgaaa atatggtcgc tcattaaaag gtcagttaat aagaggtaaa
      241 gtatctggaa gaagatatca gaggatttct ttggttgcag gtctaacaaa tggtgagtta
      301 atcgttccaa tgacttacga agagacgatg acgagcgact tttttgaagc ttggtttcag
      361 aagtttttct taccaacatt aaccacacca tcggttatta ttatggataa tgcaagattc
      421 catagaatgg gtaagttaga actcttgtgt gaagagtttg ggtataaact tttacctctt
      481 cctccctact cacctgagta caatcctatt gagaaaacat gggctcatat caaaaagcac
      541 ctcaaaaagg tattaccaag ttgcaatacc ttttatgagg ctcttttgtc ttgttcttgt
      601 ttcaattgac tatataaatt gtctaagcga aacaaccgat aagaattggc acaaaagcga
      661 ccgtgttttt gttaccaata caggaaaaac agttcatagt tctatcttga gcaagtctct
      721 ccagcgagca aacgaacgcc ttaaaaaacc aattcccaaa catctgtccc ctcacatctt
      781 cagacacacc actattagca tcttatcaga aaataaaatt cctttaaaaa caatcacgga
      841 cagggttggt cattccgact ctgaagtcac tacttccatc tacacccacg tcacaaagaa
      901 catgaaagat gaagcaatca atgtactgga taaagttatg aaaaagattt tttaaaaagt
      961 tttgcccctt ttttgtcctc taaatacaaa aatagccctt cggataaaat ccgaggggct
     1021 agaaacgttg ttaaatcaac ggccgaactt ttgaatttca tggttcggga taaaatagtt
     1081 cactgaacta ttttattttt taaggttgta gaatgatttc aatccacgat attcagctac
     1141 ttcaccaagt tggtcttcga tacgaagcaa ttggttgtat ttagcgatac ggtctgtacg
     1201 tgaaagtgaa ccagtcttga tttgtcctgc gttagttgca actgcaatat cagcgattgt
     1261 tgaatcttca gtttcacctg aacggtgtga tacaacagca gtgtaaccag cttctttagc
     1321 catttcgata gcttcaaaag tttcagtaag agtaccgatt tggttaactt tgataaggat
     1381 tgagttagca gcaccttctt ggataccacg tgcaaggtag tcagtgtttg ttacgaagaa
     1441 gtcgtcacca acaagttgta ctttcttacc aagacgttca gtaagagctt tccaaccatc
     1501 ccagtcgttt tcatccatac catcttcaat agtgatgatt gggtatttgt taaccaattc
     1561 ttcaaggtag tcgatttgtt ctgcagatgt acgaacagca gcaccttcac cttcaaattt
     1621 agtgtagtcg taaactttac gttctttatc gtagaattct gatgaagcac agtcaaatcc
     1681 gataaatacg tctttacctg gtacatatcc agcagcttca atcgcagcaa ggatagtttc
     1741 aacaccatct tcagttcctt cgaaacgagg agcgaatcca ccttcgtcac ctacggcagt
     1801 ttccaaacca cgtgatttaa ggattttctt aagagcgtgg aagatttcag caccgtaacg
     1861 aagggcttct ttaaatgttg gcgcaccaac tggcaagatc atgaactctt ggaaagcgat
     1921 tggagcgtca gagtgagaac caccgttgat gatgttcatc attggagttg gaagaacttt
     1981 agtgttgaat ccaccaaggt agctgtaaag tgggatttca aggtagtcag cagcagcacg
     2041 agctacagcg atagacacac cgaggattgc attcgcaccc aatttacctt tgttaggagt
     2101 accgtcaagt gcgatcatag cacggtcaat agcttgttga tcacgtacat cgtagccaat
     2161 gatagcttca gcaatgatgt tgtttacgtt gtcaacagct ttttgtgtac caagaccacc
     2221 gtaacgagat ttgtcaccgt cgcgaagttc aactgcttcg tgttcaccag tagaagctcc
     2281 tgatggaacc ataccacgtc cgaaagcacc tgattcagtg taaacttcta cttcaagtgt
     2341 tgggttaccg cgtgagtcta ggacttcgcg agcgtaaaca tcagtaataa ttgacatttt
     2401 ttactctcct tatgagttaa attttttaca cctctataat accttaaaac ccctcctttt
     2461 tcaagaaaaa acgttatctt tgtgcaactt ttccttaact ttataaagta atcgctttct
     2521 tttgtctgtt ttattctaac ttttatgata tactgttttc atgacagatt tatcaaaaca
     2581 attacttgaa aaagctcatg gtgggttaaa aataaatccg gatgaacaaa gacgctatct
     2641 tggtactttt gaggaaagag ttcttggata tgtagatatt gacacagcaa atagccctca
     2701 gttagaaaaa ggctttttat ttattttaga aaaccttcag gaaaaagcag agccactatt
     2761 tgtgaagatt tcaccaacta tcgaatttga taagcaagtt ttctacttaa aagaagcaaa
     2821 agaaactgat agtcaagcca ccatagtatc tgaagagcat attacttctc cttttggcct
     2881 ggttattcat agcaatgcac cagttcaagt agaagaaaaa gaccttcgac ttgcttttcc
     2941 aaaactttgg gaagttaaaa aggaagaacc agccaaaaca tccttatgga agaaatggtt
     3001 tagctaaatc ttgcacatat ttaataagtg cccaatattg gcagccgtgc gctccagata
     3061 gagactggca tttttcaaac tatcttctaa aggttcactt ttctccaaaa tagaaaagac
     3121 agcttggata ttttcaaatg gtaggggagg taaatcttca gcaagactac cgcaaatagc
     3181 aataacagga actccaacag gggttctttt tgcaacacct ataggcgctt tcccagcaaa
     3241 gctttgacta tcaagtcttc cttctccaac aacaaccaag tcagcatctg aaactttctt
     3301 atcaaagttg attaagtcca agcaggtatc aattccagac acgatacttg cctgagcaaa
     3361 ggcacacaaa ccaccagcaa ggcctccacc tgctcctgct cctttaattt ctaatgttgc
     3421 aggtgagaat ttttcataaa aatcttggat cgcctgatct acgactgcaa acatagtcgg
     3481 atgtagacct ttttgattgc caaaagtgta agtcgcacct tgatgaccac ataagggact
     3541 cacgacatct gctagaatat gaatttgaac accttcagga attttatagc aattttctgt
     3601 tgaaacagaa gctaagttta ataaggattg atcggaagca ggcaagacat ttccatccct
     3661 atcataaaat tgataaccta aaccagcagc aatccccagt cctccatcat tactggccgt
     3721 gccaccaaca ccgatataaa tatctttaat ccctttagaa atgagatgga gaatcaactc
     3781 tccaatacca caagtttgga tttgaagtgg atttcgtttc tctagcggaa tttttccaag
     3841 accaaccaag tcagctactt caaatagtgc cagttcccct ttttgaaaat agcgcatggc
     3901 ttctttttgt ccaaaagggt ctgtcacttg gatccatttt tcttttaggt caagagaatg
     3961 tcggatagca tctacagtac cttctccccc atcaccaaca gggcagagga gacattctac
     4021 atctgctatc gattgttgga agcctctttt tattgcttca gctacctgtt gagctgtcaa
     4081 gctttcctta aacgaatccg gtgcaattac aatcttcata ttttccctca ttctaaacag
     4141 tcaatcaaag gaagaacttc taaaaaatcc ctcttgtcaa catgatgtgg tatttctttt
     4201 ttgagcattt ctttggaaca aaaggcgatt cctaactccg ccgacttcaa cattaataga
     4261 ttattgaccc catcaccgat tgccaccgtt ctttctttag aaagttttag tttctttctc
     4321 catttttcca gagtttcttt tttgacctgg ggacttataa tttgtccaac taattttcct
     4381 gttaaaagac cttctttgac ttcaagctgg ttggcagtga aataggcaat accaagggat
     4441 tttgctaatc tctccaacta ttggtgtaaa tccaccagac accagaccaa ctaggatgcc
     4501 attcttttgg agaatagaga tgaactctgg gacatttagc gatagatgaa ttgagttgaa
     4561 gacgttatca aagaccaaaa taggaagacc ttccaacaag gacactcttt ttcttaaact
     4621 gctttcaaag accaactctc ctcgcattgc tcgacttgta atctgcgaaa tttccgcctc
     4681 atgacctgcc tctctcccta aaagatcaat cacttcttct aggattaagg ttccatctac
     4741 atccaaaaca cacaagcctt ttacttgaga catcagttct cctctctaaa cagcctaaaa
     4801 attgtatgaa gtcatcatac gattttatct attaattaac taaactatgg tacaagtcaa
     4861 ggtatgactt gcaggctgta tcccatgaga agtcactctc catagcttgt ttttgtaggt
     4921 ttctccaaat gtctggatgg tttctataca agtccaatgc tgtttggaaa gtccaattta
     4981 accaataagg agatagattg tcaaagctaa agccagtacc gcttccttcg attggattga
     5041 aagcgcgaac tgtatctcgc aagcctccaa cttcatggac caatggcaag gttccataac
     5101 gcatagccat catttgagac aagccacacg gttcaaaacg acttggcatg aggaagaggt
     5161 cacaagcagc gtagatttcc tgagcaagtt tgacatcaaa agtgatattt gttgatagct
     5221 tgtctgggta aatctgagcc aaccatgaga aagctccttc aaaggctgga tcgccagttc
     5281 ccaaaagaac aatctgaaca tcttcttgca agatatggtg aagactttcg accaccacat
     5341 caaaaccttt ttgacgtgtc aaacgagaaa caattcccac cagtggaacg tctgctctaa
     5401 caggcaagcc aactctttct tgcaattttg ccttattttt ggctttccca gacaaatctt
     5461 cctgattgaa atgatagtct aaaagagcat ccgtctgagg attataaaga tcagcatcaa
     5521 tcccattcac gataccagat actttaccag actccatttt aagaatctga tccaaattac
     5581 atccaaactg actagtcata atttcatgag catagctagg tgaaacggtt gaaacacggt
     5641 tcgcatagag aatacctgcc ttcatccagt tcagacagtt gttccatcga agggtgccat
     5701 cagcgtaacg ttcaaggcca actccaaaca aatcacccaa cattccttct gaaaattgtc
     5761 cttggaattc taaattatga atggttaaaa ctgtttcaat gtcctcatag gcttgaatcc
     5821 aacggtattt ttccttcaac aagaaaggaa tcatagctgt atggtagtca tgaatatgga
     5881 gaagatcagg aataaagtca atcctttcca tagcctcaat ggcagccagt tggaaaaagg
     5941 caaagcgttc tccgtcatca aaatcaccgt aaacatgacc acggaagaaa taatattgat
     6001 tgtcaataaa gtagaaggtt acaccattta atactgtttt cttaattcca caatactgtc
     6061 tgcgccaacc aacgctcacc tcaaaatgaa gcacatcttc aatctgattt ccaaatttag
     6121 cctctaccat atcatagtag ggtaaaatca ctgcaacttc gtgcccagct tttaccagtg
     6181 attttggaag agcgccaatg acgtctccca aaccacctgt ttttgaaaag ggtgcaccct
     6241 ctgctgctac aaataaaatt ttcatgaatg aatatcctct gttactttag cacctttctt
     6301 aaccacaact ggatgttctg cagttcctcg aatcacaaca ccaggctcaa cttcaacccc
     6361 tttgtccaag atagcatatt cgacctgagc cccttctcca ataacaacac gagggaagag
     6421 caggctatct ttaaccaagc tatccttatg gacatgaata ttacgtgata gaacagaatt
     6481 agctacttga ccttcaataa tactaccaga ggcaaactga gaagtgctta ccttagatgt
     6541 attagcatag taagttggct cttcgttttt gacctttgta taaatctttt ggtttggtga
     6601 gaaaagagaa tagaattttt gtgattcaag catatcgata ttcgcttgat aataagattt
     6661 aacagagtga atattggcta gatagcccgt gtactcgtag gcgaaagctc cctcttttac
     6721 agccaaatcc cgtaaaacat agcgcaattt ctttggatgt tcttttttag cttcttcttc
     6781 caagtgttca atcaaccaag gtgtatcaac gacaaagata tctgtagaca tattgaacgt
     6841 ttcagctgtt gacttgctat caaagagttt atgagaaaga acatggtctg tttcatctac
     6901 atccaagatt gcatttactt ctgaaatatc tttcttagct agttttttat aaactacagt
     6961 gataggctct tttgttgtac tatgtaggtg gaaaacttgg ttcaaatcaa tgttaataag
     7021 aacatcgcag ttgagggcaa ccgtttggtt tgagccagaa cgtttcaaat aagtaagaag
     7081 ctgttggtag tattcttttc caactgtact actttctaca cgggtattgt aaattcctag
     7141 atagtaatga ctaagaaggg ttgataagcc ccactcgcgt cctgaacgaa tatggtcaaa
     7201 tactgagctg atattatcct gctggaaaat accaaagaca ctacgaacac ctgcattagc
     7261 aaggcttgaa agtgggaagt caatcaaacg atatttccca ccaaatggca aacttgctac
     7321 tggacggtgg tccgtcaatg tcgacatatt gtgaaaacca actgtatttc ctaaaatggc
     7381 agaatattta tcaatcttca tctgttgcta cccccactac ttcattatat cctacaactt
     7441 gtacttcatc tgttccatca atttcgacac cgtcagaaat aatcgcacct tcaccaataa
     7501 tggcacgttt aatcttagct ccttgaccaa tgatagctcc actcatgata actgaatcaa
     7561 ggacttccgc tccttcgcga acttgcgcgc ctgttgaaag gatagaatgt ttaacagttc
     7621 catcaacgaa acatccgtct acaactaatg agtcttccac atgagcattt gccccgagga
     7681 agtttggtgg tgaaatcaag tttcttgagt aaatcttcca ttgacggtta cgactatcca
     7741 aggcattttc tggagaaata tactccatgt tcgcttccca aagtgactca atagtaccaa
     7801 catctttcca ataaccacta aattcgtaag cataaacact ttcacctgac tcaaggtaat
     7861 ttggaatgac atttttccca aagtctgaca tgccaacctt gctcttttca gcagcgacta
     7921 acatattacg aaggcgttgc caatcaaaaa tgtagattcc catagaagct tttgtagatt
     7981 taggttgagc tggtttttct tcaaattcaa caatacgatt gttagcatct gtgttcatga
     8041 taccaaaacg gcttgcttct ttaagaggga cgtctaaaac tgctactgtc aagctggcat
     8101 tattatcctt atgagactgg agcatatcat catagtccat tttgtagatg tgatccccag
     8161 acaaaatcaa gacatactca ggattgacac tgtcgatata gtcgatattt tggtaaatag
     8221 cgtgactagt cccctcaaac caacgatttc cttcacttgc agaataaggt tgaagaatag
     8281 agacacctga attgataccg tctagtcccc agcttgaacc attcccaata tggttgttga
     8341 gagcaagtgg ttgatactgt gtaacgaccc caacattatg aatccctgag ttggcacagt
     8401 ttgatagggc aaagtcaatg atacggtagc gcccaccaaa ttgcacagct ggttttgcga
     8461 tgctttgagt gagtttaccg agacgagttc cttgcccacc agcaagaatc aaagctaaca
     8521 tttcattttt cattttctac tcctttttgg tttttatttg tgacggtttt agtagatttc
     8581 aagcgacgtt tgattttcca tacacttgct cccatagccg gtagagtaaa ggttaaggtc
     8641 tgctcataat ctttccatag tccttcttgc gtttgaacag tttgattatg ttctttccaa
     8701 acgcctcccc actcttccaa ctcagtattc catacttctt cgtaaattcc tgcaacgggt
     8761 agtccgattg taaaatcttt ccgctcaaca ggtaccatgt taaagataca gattaacatt
     8821 tctccctttt tacccttacg aataaaggaa agaacactct ggtctcgatt atccgcatca
     8881 atgatttcaa taccatcata gctggtatcg atttcccaca gacagcgatg atctttgtaa
     8941 aactggttta gctgagaagt gaaatacttc atcttagcat tcattgggtc ttctaggtta
     9001 gaccattcca actgttcttc agatttccat tctaggaatt gaccgtattc gctacccatg
     9061 aagagcaatt tcttaccagg gtgacaaatt tggtacgtat agagattgcg caagcctgcg
     9121 aattgattgt aacgatctcc ccacatctta tgcatcatac tcttcttgcc atgaaccact
     9181 tcatcgtgcg agaatggcaa gagataattc tccttgaaaa catacataaa gctgaaagtc
     9241 accaggttaa agtcatattt acgatagatc ggatcttctt cgtagaaacg gaggatatca
     9301 ttcatccagc ccatgttcca tttgtagtca aatcctagac caccaatctc tttcattccc
     9361 gtaatcttgg tcgcagacga actttcttct gcaatcatca tcacatttgg atattctaac
     9421 ttaataacct cattcaagcg ctgaaggaaa taataacctt catagttgag atttccgcca
     9481 tctttattag gtgtccatgg agcatcatca tagtccaaat agagcatgtt gctaacagca
     9541 tccacacgaa taccatccaa atgatagaca tcaatccaat gcttaatgca agaaattaag
     9601 aaggactgga cttcattttt tccaaggtca aaattaaggg caccccaacc atggttatga
     9661 gccttattat ggtcttggta ttcaaaagtc ggtgtcccat cataataggc taaggcatca
     9721 tcgttgatgg taaagtgacc tggtacccag tccacaataa ccccaatatt atgggtatga
     9781 cactcctcga caaaatcttg aaactcctct ggtcggccat aagcatgctc taaagcgaag
     9841 taacccataa gctgataccc ccaactcaag cccaaaggat gggacatcaa gggcataaac
     9901 tcaatatgag tatagttcat ttcaacgaga taaggaatga gttcatcctt gagctgggca
     9961 aaactataag gactgccatc agaatttctt ttccatgatc cagcgtgaac ttcataaata
    10021 ttgacaggac gctcttcaaa gccccaacgt tttcttcgtg ccagccaaag tccatccttc
    10081 catttcttct caggaagctc tgttaagatt gcccctgttc ctggacgagc ctcatacctg
    10141 acagcaaaag ggtcaatctt catcagttga tgaccatttt gacgtgtgac atgatatttg
    10201 taaatatgcc cttcttgagc catattggta aagacttccc agaccccaaa atcatttctt
    10261 accattggaa tctgattttc aatccagttg gtaaaatcac caaccaagtg aacagcctga
    10321 gcattaggtg cccaaacacg gaaggtatag ccatgctctc catttagttc ttccctatgt
    10381 gctcctagat aatgttggag ataaaaattt tcacccgtca taaaggtttt taatgcttct
    10441 ctattatcca tatactcccc ttctcctgta agcgttttct atgtttttat tatactacct
    10501 ttttagagaa gattcaagta aattactata cttctttaat tattttgaaa atctacaaca
    10561 agttcactta ctcgttcaat tgtaaatcaa tattttttca aaaaattgcg aaaacgcctt
    10621 tctttttcta ctatagtgaa atgaaataaa acatgcgcaa atcgattaag gactttaatc
    10681 taatttctaa caatgtctta gaa
//
LOCUS       DAVHKZ010000056        10680 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000056 DAVHKZ010000000
VERSION     DAVHKZ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10680
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.056"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            62..358
                     /locus_tag="VVO74_001993"
     CDS             62..358
                     /locus_tag="VVO74_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU5695970.1"
                     /translation="MDTPDENGYVADNYRITYLEAHIKAMRDAIYQDGVDLLGYTTWG
                     CIDLVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYKDVIDSNGASIG"
     gene            479..1423
                     /gene="manA"
                     /locus_tag="VVO74_001994"
     CDS             479..1423
                     /gene="manA"
                     /locus_tag="VVO74_001994"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU5695971.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(1444..2807)
                     /locus_tag="VVO74_001995"
                     /pseudo
     CDS             complement(1444..2807)
                     /locus_tag="VVO74_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821651.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3035..3784
                     /locus_tag="VVO74_001996"
     CDS             3035..3784
                     /locus_tag="VVO74_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU5695972.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(3804..4259)
                     /locus_tag="VVO74_001997"
     CDS             complement(3804..4259)
                     /locus_tag="VVO74_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU5695973.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4279..5454)
                     /locus_tag="VVO74_001998"
     CDS             complement(4279..5454)
                     /locus_tag="VVO74_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU5695974.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5513..6358)
                     /locus_tag="VVO74_001999"
     CDS             complement(5513..6358)
                     /locus_tag="VVO74_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU5695975.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6483..7040
                     /locus_tag="VVO74_002000"
     CDS             6483..7040
                     /locus_tag="VVO74_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU5695976.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7059..7526
                     /locus_tag="VVO74_002001"
     CDS             7059..7526
                     /locus_tag="VVO74_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU5695977.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7615..8244
                     /gene="upp"
                     /locus_tag="VVO74_002002"
     CDS             7615..8244
                     /gene="upp"
                     /locus_tag="VVO74_002002"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU5695978.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8418..9008
                     /gene="clpP"
                     /locus_tag="VVO74_002003"
     CDS             8418..9008
                     /gene="clpP"
                     /locus_tag="VVO74_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU5695979.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9087..9335
                     /locus_tag="VVO74_002004"
     CDS             9087..9335
                     /locus_tag="VVO74_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU5695980.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9437..10597
                     /locus_tag="VVO74_002005"
     CDS             9437..10597
                     /locus_tag="VVO74_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU5695981.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDSLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
BASE COUNT         3394 a         2122 c         2278 g         2886 t
ORIGIN      
        1 actattatat aatgcttttt gattttagtt tagtattatc gtagaaaatg gactcggtgc
       61 tatggataca ccggatgaga atggttatgt agcagataac tatcggatta cttacttaga
      121 ggcccacatc aaggccatgc gagatgccat ttaccaagac ggggttgact tgcttggtta
      181 tacgacttgg ggctgtatcg atctggtttc agctggcaca ggggaaatga ataagcgcta
      241 tggctttatc tatgtagatc gagataatgt aggaaacgga gctctcaaac gtagcaagaa
      301 gaagtccttc tattggtaca aggatgtcat tgatagcaat ggtgcaagca tcgggtagag
      361 cacatttgtt tactattttt ataaaatctt ctccctgctt tataagatgt aaaaaagagt
      421 tcaattcgaa ctcttttttt gctataatga ggggagaaaa atcagacagg agatcgacat
      481 gtcagaacca ttatttttac aatcagttat gcaagaaaaa atctggggtg gagccaagct
      541 acgtgatgag tttggctacg acatcccaag tgaaaaaatc ggagaatatt gggccatctc
      601 agcccatcca aatggagtct ctaaagttgc caatggtcgt tacgagggaa cagatcttgc
      661 tactttgtat gcggaacacc gtgaattatt tggcaatcgt ccagaacctg tatttccact
      721 tttgaccaag atcctcgatg ccaacgactg gctcagtgtc caagttcacc cagacgatgc
      781 ttatggactc gagcatgaag gcgaactcgg aaaaacagaa tgctggtaca ttatcgcagc
      841 ggatgaaggt tcagagatta tctacggtca caatgccaag tcaaaagaag aactccgcca
      901 gcaaatcgag gataagaact gggatgcgct gttgacaaaa gtgccagtta aagcaggaga
      961 tttcttctat gtaccaagcg gtaccatgca cgctatcggg gcgggtatct tgattcttga
     1021 aacccagcag tctagcgata ccacttaccg tgtctatgac tttgaccgaa aggacgataa
     1081 gggcaacttg cgtgaacttc accttgaaaa atctatcgat gtcttgaaca ttggtgaacc
     1141 cgcaaatagc cgtccagtga caatcaaagc agatgatcta cgttccactc tccttgtatc
     1201 caatgatttc ttcgcagttt acaaatggga aattactgga aaagttaact ttgaaaagac
     1261 agctgactac agcttgttga gtgtcttggc tggtcaaggt caactaactg ttgacgggaa
     1321 aaactatcca atccaaaaag ggagacactt tatcctacca agtgatgttg aatcttggac
     1381 tttagaaggg caagatttgg aattgattgt tagtcatcca taaaaagaaa gggcctgagt
     1441 tcactactca agtccttttt gattacataa attgggcgat gaagaccacg atgatgattg
     1501 gaatgacgaa acgaagaaac gaaggaggaa gagccagact tggaaaagta cttgtttcca
     1561 ggctctttca tcgagatgga gttcctccat aacaagagcc tttttaaaga tatagcctgt
     1621 aaaaagtgaa aggcagagag ctccaaatgg catgagaaga ttggaaacca agaaatccat
     1681 ggcatcaaag aaagtcttac caaagatgtg aacatccgcc ataactccat aggatagggc
     1741 tgaaggaatg ccaaagacaa aggtcaaaat tcctaaaata acactccatt tggcacgttt
     1801 gctgttatcc tggttggtga tattgcccac attgatctcc agcatcacga cagaaaaagt
     1861 gactggcgca aaaaggaaga gcaagaggaa aaggacgtag aaaatggttc caaaaggcat
     1921 cttgtcaaag agttgaggca agacgataaa gagcaagctc ggtccccctt cagactggat
     1981 attgaagggg gaccgagctt ggaaaatggc tagacctgcc atgatggata tcgagatatt
     2041 catggctacg atggagattc ctgactggac taggttggtt ttcttgtcca agtaagaagc
     2101 ataggtcaac atgactgtaa cccctagtga gagggcaaag aaagattgtc ccagagcata
     2161 gaggagacca gcgctagtca gttttgaaaa gtctggtttg aggaagtaaa gaaccccttc
     2221 catggcattt ggcaaactga gagagcgacc gatgataaca acaaagatga taaagagcag
     2281 gggcatcatg actttcgaag ctctttcaat ccctttttga accccacgtg atacaataaa
     2341 gatatttaat aagataaagg ctgcttgagc tcctagggca atggctggat ttgaaatgat
     2401 tgaagtaaat aactgagcat aatcacccgt tccaccaagt tggaacaatt tcccaaactc
     2461 aatacctaga tagactagaa tccatcctcc gataacactg taaaaagata agaggataaa
     2521 gagggcaaag gcgccaatcc aaccgataaa gttgtacttg ttattcttgc ccagttttcc
     2581 aaaggttttg atagcggaaa cgccagcact acggccaagg gcaaactcag ccagcaggag
     2641 agggaaaccg attaaaatag tggaaatgag aaagattagt aaaaagcctc catcgccatt
     2701 agcagcagtc atgtagggaa acttccaaac ggaaccaagc ccgatggcca gccagcagat
     2761 gctagaataa aaccaagttt cgacccccat tgtgattttt ctgacatagt taaactctga
     2821 tctccttttt caaaataaga aaaagctact tgagttgtca aatagccttc tgtttgattg
     2881 atagacttga ctatcctatc atgttttcta aggtctgtca agaaaatcat tttcaagttt
     2941 tcacaccttt ctcaaaaaag ttaaaaaatt ttctcaaaaa cgcttgactc tgacctaagg
     3001 ggaggggtta tactatcatt gtaaggagga aatcatgtac catataaaag aagctgcgca
     3061 gctttcaggt gtctctgtca agaccctgca tcactatgac aagataggac tcttggtccc
     3121 cttaaagtcg gaaaacggct atcgaaccta cagtcaagag gatttggaac gccttcaggt
     3181 cattctttac tacaaatatc taggcttttc tttagagaaa atagcagagc tgttaaagga
     3241 agaaaggaca gatttattgc cccatttgac taggcagttg gactatctaa ctcgcgaaag
     3301 gcaacatctg gataccttga tttccacctt gcaaaaaact attcaagaac aaaaaggaga
     3361 aagaaaaatg accattgagg aaaaattcac gggatttagc tatcaagaca atcaaaaata
     3421 ccaccaagaa gcggtagaga aatatggtca agaagtcatg ggacaagcgc tcgaacgcca
     3481 aaaaggtcac gaagacgagg ctacggccgc ctttaaccaa gtctttcaaa ctttggcaca
     3541 aaatcttcaa gttggtttac ctgcaacagc aaccgaaaac caagagcaag cagccaagct
     3601 cttgcaagcc attcgcactt atggatttga ctgctctatt gaggtattcg gtcatatcgg
     3661 taaaggttac gtctataacc cagagtttaa ggaaaacatt gacaagtttg gttctggaac
     3721 agcccagtac acgtcagatg ccattgcagc ttacgttcag acaaatgcag aaaaaatagg
     3781 ctaggaattt cctagcctat tttttacttc aaatcataaa gccagtcgtc accgtttttg
     3841 tagtaaaaga attcactgag atcttcttct agaaacacac gaagcatatc agacatatca
     3901 tcggttgcaa gttttagatg agaaagattt tcaaagtcct cccaccaaac tttcccttcg
     3961 tctgaagact ggagttcacc agtaaagtgt tctgtcttgt aaaaaaggac gacataacga
     4021 taatccttgt cgtcatacca gtttttgata ccacagagtt ggggtttgga aatgatcaga
     4081 ccagtttctt ctttcacttc acgaatgaca gcatcgacaa aggattcgcc acgttcaaca
     4141 tgaccaccag gaaaagtaat gccaggccag tcgggactaa ctcggtcttg gaccaggacc
     4201 ttatctccgt ttttaatcat acacatgtta acaaattcga ctgcctctct tctgttcatt
     4261 cttcacaacc tttaatcttt aatcataatg cagacttccc gccacccagc cggtacagag
     4321 ggcagaagtg atgttaaagc cacccgtgtg ggcattgata tccataactt cgcctgcaaa
     4381 gtggaggcca ggtaccagct tactttcaag ggttttagga ttgatttcct tgagactgac
     4441 tccacccttg gtaacaaagg actttgcaag ggacattttt ccagttacag gaattttaag
     4501 ttctttaatg gactggacaa gctgttctcg ttccttttca gtcagctgtt tgactttttc
     4561 aggatatcct tgtacaaaaa attcggccaa gcgttctggt aacaaggttt ttaaagcgtt
     4621 tttcaaggat ttttcccgat tttcttctag aaatgtaacc aagtccttct cagaaagttg
     4681 aggcaaaaca tcgagtgaga gaacctcccc acctttgaca aagctagaca tgcgtagggc
     4741 agcaggacct gacaaaccaa agtgggtaaa gagtaaatca tgagtgatga catgcttacc
     4801 ataacttagg gtcacatcgt ccaaagaaat cccttgtaag gctttatgtg gaaaatctgt
     4861 taataaagga ctttcagcag cctcaagatc ggtgatggta tgcttaaaat ggcgagcaat
     4921 ctcgtgacca aaaccagtcg aaccagtcga aggataagac ttaccacctg ttgtgacaat
     4981 gagtttctca caagtgaagg tttgatccgc tgacttaagg acaaactggt tatctacttt
     5041 tttaacagaa acgatttcta tttgagtagc aacttgacca cctagttcgg tgattttctt
     5101 ttccaaagct tcgataatag tccgagactt gtcactggct ggaaagacgc gtccgtggtc
     5161 ttcgacctta agtttaacac cattttctgt aaaaaagttg atgatgtcat gattatcgaa
     5221 ctgggagaaa acactgtaaa gaaagcgtcc gtttccagga attccagcta gcaggttgtc
     5281 taagctacca ttgttggtca cattgcaacg tcccccacca gtcccagcta atttttttcc
     5341 aagtttccga tttttttcga tgaggagggt tttctgtcca taaaagctac tggaaatcgt
     5401 agccatcata ccagcaggtc ccccaccgat gacaatagta tcaaaatgtt tcatagctct
     5461 attgtaccac aaaaaaacaa gagatgatgg tcacctcttg tcaagaatgc aattaatcaa
     5521 tttcatagcc catcagcaaa ccgccctctt ctgcatagaa actgcagaga ccagaggttg
     5581 gtagaatttt aatatccgct tgtgggaagg tttcacggat tcgctctgag agctgttgac
     5641 aacatttttc gttattgcgt tgggccatga caatacggcc accagcatat ccagctttta
     5701 ctaactcatc ataggcagct tgaactgatt tctttgatcc ccttgctttt tgtagcaatt
     5761 cgagagtccc agtttcacta gcttttccga ccatacgaat gttgagaagg ccaacgaccg
     5821 taccgataag cttgctcaaa cggccgttct tcaccaagtt atcgactttg gctaggacaa
     5881 agagcaactt agttttttct tgataggcgg tgatagcttc aaccacttct tcaaaagaca
     5941 agccctggtc aatcaagtca ttcaattttt ctacgagtag gtcaacttca ccaccagcag
     6001 ataaactatc aatcacatga atcttagtgt caggatggtc ttccagataa atattctttg
     6061 ctagttgagc actattgtga ctgccagaaa gggtacctgt gatggttact aggaaaatgt
     6121 ttttggcacc ttcaaatgct cgcaaatagt catctgggct tggacaagct gattttgaag
     6181 cttctgcagt tgcatacatg gtttccatca tttggtcaat atcgagactg gcgtcatcaa
     6241 caaagacctg atcagctact tgaatggtta aggggacact tacaaaggtt gtgttaatag
     6301 ctggtgttgg cagttgacga taatcacaac cagagtcagc aataatcttc caagtcatag
     6361 aaattctcca tctttgtcag ttatacattg acaaaggttc tgtctttttt tacaattata
     6421 tcatgaaaac tcttgaaaca aaagcatcat ccgtctgttg tgacaagtag aaagaaaatg
     6481 ttatgtctga acgtagaatc tctgaaaagt ctcttgaaaa tctcagaaaa tcaaatcaag
     6541 aatccaattt attaaccaga gaagccattg aaacagccct cttgcaactc ttggaaaaaa
     6601 aggagctgac caagattagt atttctgaat tggtcaaacg tgcaggtgtt tcgcgtgcgg
     6661 ccttttatcg caattatgac tccaaagagg aaattttaga gagcgtcttt aaacgaactg
     6721 tccacaatat tatggaacag ctgcatcatt acgatttaaa gacagacctt tatttggttt
     6781 gggttcacct tttccgggag gccagaaagg aagctagagt aattcaattg gccttggatt
     6841 accatctgga aaaaatcttt gtccaagcca tgcaggaatt tctagaaaaa taccatggga
     6901 aatcaaaagg tgtcagctct tatcttcatt ccttctggag ctcagccatc gtctctgtcc
     6961 ttctaaaatg gatcaaggat ggcatgaagg taccagctga aaagattgca gatttaggtt
     7021 taccattttt taaaaaatag agaaaaagga gaaaagagat gactgaaaaa agactggcct
     7081 gggatgagta ttttgcagcc caagccctac taattgcgaa tcgttccact tgtaaacgtg
     7141 ctaaagtggg cgcgattctg gtaaaagata ataaggttat ttccactggt tacaatggtt
     7201 cggtgtcagg gactgagcat tgtattgatc acgaatgttt ggtcattgaa ggccactgtg
     7261 ttcgcaccct tcacgctgag gtcaatgcta tccttcaagg tgctgagcgt ggtgttccca
     7321 aaggctttac agcctatgta acccattttc cttgtctcaa ctgtacaaaa caattgcttc
     7381 aggtcggctg caagcgcgtg gtttatatca accagtaccg aatggacgac tacgcccaat
     7441 acctttatca agaaaaaggg acagaattga cccatttacc acttgagaca gtacagacag
     7501 ctcttaaaga ggctgatcta atgtaaaaat tatcaaaaat aaatggttta gaaagatttt
     7561 taaaccgttt tttggtataa tgagaagaat aaattgaaag aaggaattcc aaaaatggga
     7621 aaaattgaag ttattaatca cccactgatt caacacaaat tgtcaatctt gcgtcgtaca
     7681 gatacttcta caaaagcttt tcgtgagcta gtagatgaga ttgcaatgtt gatggggtat
     7741 gaagtacttc gtgatcttcc actagaagat gtggaaatcg aaacaccaat tacaaaaaca
     7801 gttcaaaaac aattggcagg taagaaattg gccatcgtcc caatcttgcg tgcaggtatc
     7861 gggatggttg atggtctctt gagcttggtt ccagctgcta aagttggcca catcggtatg
     7921 taccgtgatg aagaaacact tcaaccagtt gaatacttgg tgaaattgcc tgaggacatt
     7981 gaccaacgtc aaatttttgt agtagaccca atgttggcaa caggtggctc agcaatcttg
     8041 gctgttgatt ctcttaaaaa acgtggcgca tcaaatatca aatttgtctg ccttgtatct
     8101 gctccagagg gtgtaaaagc ccttcaagaa gctcatccag atgtagaaat ctttacagca
     8161 gccttggatg aacgtttgaa cgaacacggt tatatcgttc caggtcttgg agatgctgga
     8221 gaccgcttgt tcggtacaaa ataagatcga aaagaagaat gacttggaaa agtatttcca
     8281 gtcacgaaag gaggttgggt ttttgtttct gtctaatgaa agcagagcaa aaatttgacc
     8341 ttttttgacc aagatattat aatagtctta tcttcagtca tttgaccaac aaaattaaaa
     8401 ctcaaaagga gaaatgaatg attcctgtag ttattgaaca aacaagccgt ggagaacgtt
     8461 cttacgatat ttactcacgt cttctcaaag accgcatcat tatgctgaca ggtccggttg
     8521 aagacaatat ggctaactct gttattgccc aattgctttt cttggatgcc caagatagta
     8581 caaaagatat ttacctttat gtcaatacac caggtggttc tgtttcagct ggtttggcaa
     8641 tcgtagatac catgaacttt atcaaggcag atgtccaaac cattgttatg ggaatggctg
     8701 catctatggg aacagtcatc gcatcaagtg gagcaaaagg caaacgtttc atgcttccaa
     8761 atgctgaata catgattcat caaccaatgg gcggtacagg tggtggtacc caacaaactg
     8821 atatggctat cgctgcagaa cacttgctca aaactcgtaa taccttggaa aaaatcttgg
     8881 ctgaaaattc aggtcagtca atggaaaaag tccatgcaga tgcagaacgt gataactgga
     8941 tgagcgccca ggaaacactt gaatatggct ttattgatga aattatggcc aacaattcat
     9001 tgaactaatg atgatagaag gcaaactcga ctgggtttgc tttttttggt ataataggga
     9061 gagatttctt agaaagagga tttatcatgt ttgaaaaagt caatcgctct ggcttgatta
     9121 tctatcttta ctataatcgt gatgccaaaa aactgcagga ttatggagat attacctatc
     9181 attccaagaa acatcgttac ttacaactct atgttccaac tcaagaagtg gagcaattgg
     9241 tcggacgctt gagcaaggaa aaatttatta aaaaagttag agtttgtcat atccaagagt
     9301 tggaaacacc ctttgtgggc aatctttatc gataggaaaa cgttatcatc gaaaaagttc
     9361 aaggaaaaca ttgacaattt tctgataatt cggtatattc ttaacagact atttaagaaa
     9421 taaggagaca aaaaagatga agaaaaaatt tgccctatcg tttgtggcgc ttgcaagtgt
     9481 agcacttctt gcagcctgtg gagaagtgaa gtctggagca gtcaacactg ctggtaactc
     9541 agtagaggaa aagacaatta aaatcgggtt taactttgaa gaatcaggtt ctttagctgc
     9601 atacggaaca gctgaacaaa aaggtgccca attggctgtt gatgaaatca atgccgcagg
     9661 tggtatcgat ggaaaacaaa tcgaagtagt cgataaagat aataagtctg aaacagctga
     9721 ggctgcttca gttacaacta accttgtaac ccaatctaaa gtatcagcag tcgtaggacc
     9781 tgcgacatct ggtgcgactg cagctgcggt agcgaacgct acaaaagcag gtgttccctt
     9841 gatctcacca agtgcgactc aagatggatt gactaaaggt caagattacc tctttattgg
     9901 aactttccaa gatagcttcc aaggaaaaat tatctcaaac tatgtttctg aaaaattaaa
     9961 tgctaagaaa gttgttcttt acactgacaa tgccagtgac tatgctaaag ggattgccaa
    10021 atctttccgc gagtcataca agggtgaaat cgttgcagat gaaactttcg tagcaggtga
    10081 cacagacttc caagcagccc ttacaaaaat gaaagggaaa gactttgatg ctatcgttgt
    10141 tcctggttac tataatgagg ctggtaagat tgtaaaccaa gcgcgtggca tgggaattga
    10201 caaaccaatc gttggtggtg atggattcaa cggtgaggag tttgtacaac aagcaactgc
    10261 tgaaaaagca tcaaacatct actttatctc aggcttctca actactgtag aagtttcagc
    10321 taaagctaaa gccttccttg acgcttaccg tgctaagtac aatgaagagc cttcaacatt
    10381 tgcagccttg gcttatgatt cagttcacct tgtagcaaac gcagcaaaag gtgctaaaaa
    10441 ttcaggtgaa atcaaggata gccttgctaa aacaaaagat tttgaaggtg taactggtca
    10501 aacaagcttc gatgcagacc acaacacagt caaaactgct tacatgatga ccatgaacaa
    10561 tggtaaagtt gaagcagcag aagttgtaaa accataatag aaaaatgttg aaatagggaa
    10621 tgagcctttg actcactccc tgtttcgata tttaatactc ttcgaaaatc tcttcaaact
//
LOCUS       DAVHKZ010000057        10515 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000057 DAVHKZ010000000
VERSION     DAVHKZ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10515
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.057"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            60..929
                     /locus_tag="VVO74_002006"
     CDS             60..929
                     /locus_tag="VVO74_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU5695982.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            933..1889
                     /locus_tag="VVO74_002007"
     CDS             933..1889
                     /locus_tag="VVO74_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU5695983.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            1889..2653
                     /locus_tag="VVO74_002008"
     CDS             1889..2653
                     /locus_tag="VVO74_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695984.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            2653..3363
                     /locus_tag="VVO74_002009"
     CDS             2653..3363
                     /locus_tag="VVO74_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5695985.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            3671..4327
                     /locus_tag="VVO74_002010"
     CDS             3671..4327
                     /locus_tag="VVO74_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU5695986.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIISL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            4435..5530
                     /gene="prfB"
                     /locus_tag="VVO74_002011"
     CDS             join(4435..4506,4508..5530)
                     /gene="prfB"
                     /locus_tag="VVO74_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU5695987.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSYEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            5548..6240
                     /gene="ftsE"
                     /locus_tag="VVO74_002012"
     CDS             5548..6240
                     /gene="ftsE"
                     /locus_tag="VVO74_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU5695988.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            6233..7159
                     /locus_tag="VVO74_002013"
     CDS             6233..7159
                     /locus_tag="VVO74_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5695989.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            7445..9625
                     /locus_tag="VVO74_002014"
     CDS             7445..9625
                     /locus_tag="VVO74_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU5695990.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEV
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     NAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            9677..10492
                     /locus_tag="VVO74_002015"
     CDS             9677..10492
                     /locus_tag="VVO74_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU5695991.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
BASE COUNT         3109 a         1866 c         2342 g         3198 t
ORIGIN      
        1 agaacctatc aaaaagtgag ggaaaaccct cggaattata aatagaaaga gtgaatctta
       61 tgctccaaca actcgtaaat ggtttgattc taggtagtgt ttacgcgctg ttagccctag
      121 gatataccat ggtttacgga attatcaagc tcatcaactt cgcccatggt gatatttata
      181 tgatgggagc ctttatcggt tatttcttga tcaattcttt ccaaatgaat ttctttgtag
      241 cgcttattgt agctatgcta gcgacagcta ttcttggtgt cgtgattgag tttcttgctt
      301 accgaccttt gcgccactct actcgtattg ctgttttgat tacggctatt ggggtttctt
      361 tcctattgga gtatggaatg gtctatctgg ttggtgccaa tacccgtgcc ttccctcaag
      421 cgattcaaac agttcgatat gatttgggac caattagctt aacaaatgtg cagttaatga
      481 ttttggccat ttccttgatt ttgatgattt tgttacaagt cattgtccaa aagactaaga
      541 tggggaaagc catgcgtgca gtatcagtag atagcgacgc ggcgcaattg atggggatca
      601 atgtaaaccg tacgattagc tttaccttcg ctttgggttc tgctcttgcg ggtgcggctg
      661 gtgttctgat tgctctttat tataactctc ttgagccttt gatgggggtt actccaggtc
      721 ttaaatcttt cgttgccgca gtacttggtg gtatcggaat tattcctggt gcggctcttg
      781 gtggctttgt gattggtcta ttggaaacct ttgcgacagc ctttgggatg tcagatttcc
      841 gtgatgccat tgtttatgga atcttgttgt tgatcttgat tgtccgccca gctggtatcc
      901 ttggtaagaa tgtgaaagag aaggtgtaaa cgatgaagga aaatttaaaa gttaatattc
      961 tatggttact ccttttgtta gctggctata gcttgattag tgtactggtt tcagtcggag
     1021 tacttaatct attctatgta cagattttac aacaaattgg aattaatatt attttggctg
     1081 ttggtctcaa cttaatcgtt ggtttttcag gacaattttc acttggtcat gctggtttca
     1141 tggcgattgg tgcctatgca gcagctatta ttggttctaa atcaccaacc tacggtgcct
     1201 tctttggagc tatgcttgta ggggctttgc tttcaggagc agttgcctta cttgtcggca
     1261 ttccaacctt gcgcttgaag ggggactatc ttgcggtagc aactctgggt gtttctgaaa
     1321 ttatccgtat ctttatcatc aatggtggaa gtcttacaaa tggtgcggca ggtatcttag
     1381 ggattcctaa ctttacaact tggcaaatgg tttacttctt tgtcgtgatt acaaccattg
     1441 caaccttgaa cttcttgcgt agcccaattg gccgttcaac cctctctgtt cgtgaagatg
     1501 aaatcgctgc tgagtcagtt ggggttaata cgactaaaat taaaatcatc gcttttgtct
     1561 ttggtgccat tactgcaagt attgctgggt cacttcaggc aggatttatc gggtctgttg
     1621 taccgaaaga ttacaccttc atcaactcaa tcaacgtttt gattattgtt gtatttggtg
     1681 gactcggttc cattacaggt gcgattgttt cggctattgt tctgggaatt ttgaatatgc
     1741 ttctccaaga tgttgctagt gtgcgtatga ttatttacgc tttggccttg gtattggtaa
     1801 tgattttcag accaggtgga ctccttggaa cgtgggaact gagcctatca cgtttcttta
     1861 aaaaatctaa gaaggaggaa caaaactaat ggcattactt gaagtaaaac agttaaccaa
     1921 acattttggt ggtctaacag ctgttggaga tgtgactctt gaattgaacg aaggggaact
     1981 ggttggatta atcggtccaa acggagctgg gaaaaccacc cttttcaacc ttttgaccgg
     2041 tgtttatgaa ccaagcgagg gaacagtaac cctagatggt caccttttga atgggaaatc
     2101 accttataag attgcctctt tgggacttgg acgtactttc caaaatatcc gtctttttaa
     2161 agatttaaca gttttagaca atgttttgat tgcttttgga aaccatcaca aacagcatgt
     2221 ttttactagt ttcttacgct taccagcttt ttacaagagt gaaaaagaat taaaggctaa
     2281 agctttggaa ttgttgaaaa tctttgattt agatggtgat gcagagactc ttgctaaaaa
     2341 tctttcctac ggacaacaac gtcgtttgga aattgttcgt gcccttgcta cggaacctaa
     2401 aattctcttc ttagatgaac cagcagcagg tatgaaccca caggaaacag ccgaattgac
     2461 tgagttaatt cgtcgtatca aagatgaatt taagattaca atcatgttga ttgaacacga
     2521 tatgaatctg gtcatggaag taacagaacg tatctacgta cttgaatatg gccgtttaat
     2581 tgctcaagga actccagacg aaattaagac caataaacgc gttatcgaag cttatctagg
     2641 aggtgaagcc taatgtctat gttaaaagtt gaaaatcttt ctgtgcatta cggtatgatc
     2701 caagcagtcc gtgatgtaag ctttgaagtt aatgaaggag aagttgtttc ccttatcggt
     2761 gccaacggtg caggtaagac aactattctt cgcaccttgt caggtttggt tcgaccaagt
     2821 tcaggaaaga ttgaattttt aggtcaagaa atccaaaaaa tgccagctca gaaaatcgtg
     2881 gcaggtggtc tttcacaagt tccagaagga cgccacgtct ttcctggctt gactgttatg
     2941 gaaaatcttg aaatgggagc tttcttaaag aaaaatcgtg aagaaaatca agctaacttg
     3001 aagaaggttt tctcacgctt tcctcgtctt gaagaacgga agaaccaaga tgcagctact
     3061 ctttcaggag gggaacaaca aatgcttgcc atgggacgcg ctcttatgtc aacaccaaaa
     3121 cttcttcttt tagatgaacc atcaatggga cttgccccaa tcttcatcca agagattttt
     3181 gatatcattc aagatattca gaagcaagga acaaccgtcc tcttgattga acaaaatgcc
     3241 aataaagcac tcgcaatctc tgaccgagga tatgtattgg aaacaggaaa aatcgtccta
     3301 tcagggacag gaaaagaact cgcttcatca gaagaagtca gaaaagcata tctaggtggc
     3361 taaaacaatc cagtggattg ttttagtcgg cagatgaaga ttacgaagta atcatcaata
     3421 tagtccgggg gaccttttta gccggtagat tgagattgca aacaaatctg catctacatt
     3481 gaaagcttaa tttctaataa ttgaaaaaat cgaatgaaaa gtttcttacc ttcattcaca
     3541 gagctcgatt ttagagctct ttttgctagc ttattcatac ttttctaaat tttgaaaaag
     3601 aaatgtaagc gtttgataga tttgcaaaaa gattgtataa tagggataag aatagaaaag
     3661 gagaagtctc atggcagtta aagattttat gacccgcaag gtagtttata ttagtccaga
     3721 tacaacagta tctcatgcag cagatttgat gagagagcaa ggattgcacc gcttgcctgt
     3781 tatcgaaaat gatcaattgg ttggtttggt gactgaggga accattgcac aagcaagtcc
     3841 atctaaagca acaagtcttt ctatctatga gatgaattat cttctgaata agacaaaagt
     3901 aaaagatgtc atgattcgcg atgttgtcac tgtctcaggc tatgctagtc tagaagatgc
     3961 aacttatctg atgttgaaaa ataagattgg tattctccct gtcgtagata accatcaagt
     4021 atacggagtt attactgacc gtgacgtttt ccaagccttt cttgaaattg caggttatgg
     4081 cgaagaaggg attcgtgtac gctttgttac agaagatgaa gttggtgttc ttggaaaaat
     4141 tatttctttg attgtagaag aaaatttgaa tatctcccat acagtcaata ttccgcgtaa
     4201 ggatggtaag gtcattatcg aagtgcaaat cgatggatca attgatttac cagccttgaa
     4261 agaaaaattt gaagcaaatg gtattcaagt ggaagaaatc gctcgcactt cagcaaaagt
     4321 cttgtaagaa gggaagccca aaggcttctt ttttcatgaa aaggggatta gagcaaaaga
     4381 tggaaagaaa tgataaaata tgctataatg aaatgatgta aaaaaggagt atttatggac
     4441 atttcagtaa ttcgtcagaa aattgacgca aatcgtgaaa aattagcttc tttcaggggg
     4501 tctctttgac ctcgaagggc tagaggaaga gattgccatc ttggaaaaca agatgacaga
     4561 acctgatttt tggaacgata atattgcggc ccaaaaaacg tcgcaagaat tgaatgaatt
     4621 aaaaaacact tacaatacct tccataagat ggaagagttg caggatgaag tcgaaatttt
     4681 attggatttt ttggctgaag acgagtcagt gcatgatgaa ctggtagcgc agttagccga
     4741 acttgataag ataatgacca gctacgagat gactctactc ttgtcagaac cttatgacca
     4801 caacaatgcc atcttggaaa tccatccagg ttctggtggt actgaggcgc aggactgggg
     4861 tgatatgttg cttcgtatgt atactcgtta tggtaatgct aaaggcttta aagtggaagt
     4921 gttggattac caagcaggtg atgaggctgg tattaagtcg gtaactttat catttgaagg
     4981 gcctaatgcc tatggtctcc tcaagtcaga aatgggtgtt catcgcttag tgcgaatctc
     5041 accatttgac tctgccaaac gtcgccatac ctctttcaca tctgtagaag tgatgccaga
     5101 attggatgat actattgaag tggaaatccg tgaagatgat atcaagatgg ataccttccg
     5161 ttcaggtggt gccggtggac aaaacgtcaa taaggtttca acaggtgtac gtttaaccca
     5221 cattccaact ggaattgttg tccaatcaac agtggatcgt acccagtatg gaaatagaga
     5281 tcgcgccatg aagatgttgc aggctaagct ctatcaaatg gagcaagaga agaaggctgc
     5341 ggaggtagat tctctcaaag gtgagaaaaa ggagatcact tggggaagtc aaatccgttc
     5401 ttatgtcttc acgccttata ctatggtaaa agatcaccga actagctatg aggttgctca
     5461 ggtagataag gttatggatg gggacctaga tggttttatc gatgcttatc tcaagtggcg
     5521 aattagctaa gatagaaagg aactcacatg tcaattattg aaatgagaga tgtcgttaaa
     5581 aaatacgaca acggaacgac tgctctacgc ggtgtttcgg ttagcgttca accgggggaa
     5641 tttgcttaca tcgtaggacc ttcaggagca gggaagtcaa cttttattcg ttctctgtat
     5701 cgtgaagtaa aaatcgataa aggaagtcta tcagttgctg gttttaatct ggttaagatc
     5761 aaaaagaaag atgtcccgct tctacgtcgt agtgttgggg ttgtcttcca agattataaa
     5821 ctgttaccaa agaaaactgt ctatgaaaat attgcttacg ctatggaagt aatcggggaa
     5881 aatcgccgta atatcaaaag acgagtgatg gaagttttgg acttggttgg attgaagcat
     5941 aaggttcgtt ctttcccaaa tgaactctca ggtggggagc aacagcggat tgcgattgcg
     6001 cgtgcaattg taaataatcc caaagtattg atagctgatg agccaacagg aaatctggat
     6061 ccggataatt catgggaaat tatgaatctc ttggaacgga ttaacctaca aggaacaact
     6121 attttgatgg cgactcataa tagccagatt gtaaatacct tgcgccaccg tgtcattgcc
     6181 attgaaaatg gccgtgtcgt tcgtgacgaa tcaaaaggag agtatggata cgatgattag
     6241 tagatttttt cgccatttat ttgaagcctt aaaaagtttg aaacgaaatg gttggatgac
     6301 agtagctgct gtcagttcag tcatgattac tttgaccttg gtggcaatat ttgcatctgt
     6361 tattttcaat acagcgaaac tagctacaga tattgaaaat aatgtccgtg tagtagttta
     6421 tatccgaaag gatgtggaag ataatagtca gacaattgaa aaagaaggtc aaactgttac
     6481 aaataatgac taccacaagg tatatgattc tttgaagaac atgtctacgg ttaaaagtgt
     6541 taccttttca agtaaagaag aacaatatga aaaattaacc gagataatgg gagataactg
     6601 gaaaatcttt gaaggagatg ccaatcctct ctatgatgcc tatattgtag aggcaaacac
     6661 tccaaatgat gtaaaaacta tagccgaaga tgctaaaaaa attgaaggtg tctctgaggt
     6721 tcaagatggc ggtgccaata cagaaagact cttcaagtta gcttcattta tccgtgtttg
     6781 gggactaggg attgctgctt tgttaatttt tatcgcagtt ttcttgattt caaataccat
     6841 tcgtattacc attatttccc gcagtcgcga aattcaaatc atgcgcttgg tcggagctaa
     6901 aaacagttat atccgtggac cgttcttgtt agaaggagcc tttatcggtt tattgggagc
     6961 tatcgcacca tctgttttgg tctttattgt ttatcaaatt gtttaccaat ctgtcaacaa
     7021 atcgttggta gggcaaaatc tatccatgat tagtccagat ttatttagtc cgttgatgat
     7081 tgccctacta tttgtgattg gggttttcat tggttcattg ggatcaggaa tatccatgcg
     7141 ccgattcttg aagatttagg taaaatagct gcttttatga ggagattgta aaatctcctt
     7201 ttttgctaca agagtttttg aaaagagatg cgcagaagaa aagagcttcc aaagaagtcc
     7261 cccagagaag acttcttgat ggctaatttg aacttgaaat ttggcgcact agaaattttt
     7321 tagaaaaaag tgtaattttt ttataaaagc ctttacaaaa aaaattaaag tggtataatt
     7381 aaatcataga aagtgcaaac gttttcgtaa aacgtttgcc taaataaaaa taaaggagat
     7441 ttgaatgatg aaagatacat tcaaaaatgt cttgtctttc gaattttggc aaaaattcgg
     7501 taaggctttg atggtagtta tcgcggttat gccggctgct ggtttgatga tttcaatcgg
     7561 taagtctatc gtgatgatta acccaacctt tgcaccactt gtcatcacag gtggaattct
     7621 tgagcaaatc ggttgggggg ttatcggtaa ccttcacatt ttgtttgccc tagccattgg
     7681 aggaagctgg gctaaagaac gtgctggtgg tgctttcgcc gctggtcttg ccttcatctt
     7741 gattaaccgt atcactggta caatctttgg tgtatcaggc gatatgttga aaaatccaga
     7801 tgctatggta actactttct ttggtggttc aatcaaagtt gctgattact ttatcagtgt
     7861 tcttgaagct ccagccttga acatgggggt attcgtaggg attatctcag gttttgtagg
     7921 ggcaactgct tacaacaaat actacaactt ccgtaaactt cctgatgcac tttcattctt
     7981 caacgggaaa cgtttcgtac catttgtagt tattcttcgt tcagcaatcg ctgcaattct
     8041 acttgctgct ttctggccag tagttcaaac aggtatcaat aatttcggta tctggattgc
     8101 caactcacaa gaaactgctc caattcttgc accattcttg tatggtactt tggaacgttt
     8161 gctcttgcca tttggtcttc accacatgtt gactatccca atgaactaca cagctcttgg
     8221 tggtacttat gacattttaa ctggtgcagc taaaggtact caagtattcg gtcaagaccc
     8281 actatggctt gcatgggtaa cagaccttgt aaaccttaaa ggtactgatg ctagtcaata
     8341 ccaacacttg ttagatacag tacatccagc tcgtttcaaa gttggacaaa tgatcggttc
     8401 attcggtatc ttgatgggtg tgattgttgc tatctaccgt aatgttgatg ctgacaagaa
     8461 acataaatac aaaggtatga tgattgcaac agctcttgca acattcttga caggggttac
     8521 tgaaccaatc gaatacatgt tcatgttcat cgcaacacct atgtatcttg tttactcact
     8581 tgttcaaggt gctgccttcg ctatggctga cgtcgtaaac ctacgtatgc actcattcgg
     8641 ttcaatcgag ttcttgactc gtacacctat tgcaatcagt gctggtattg gtatggatat
     8701 cgttaacttc gtttgggtaa ctgttctctt tgctgtaatc atgtacttta tcgcaaactt
     8761 catgattcaa aaattcaact acgcaactcc agggcgcaac ggaaactacg aaactgctga
     8821 aggttcagaa gaaaccagca gcgaagtgaa agttgcagca ggctctcaag ctgtaaacat
     8881 tatcaacctt cttggtggac gtgtaaacat cgttgatgtt gatgcatgta tgactcgtct
     8941 tcgtgtaact gttaaagatg cagataaagt aggaaatgca gagcaatgga aagcagaagg
     9001 agctatgggt cttgtgatga aaggacaagg ggttcaagct atctacggtc caaaagctga
     9061 cattttgaaa tctgatatcc aagatatcct tgattcaggt gaaatcattc ctgaaactct
     9121 tccaagccaa atgactgaag tacaacaaaa cactgttcac ttcaaagatc ttactgagga
     9181 agtttactca gtagcagacg gtcaagttgt tgctttggaa caagtaaagg atccagtatt
     9241 tgctcaaaaa atgatgggtg atggatttgc agtagaacct gcaaatggaa acattgtatc
     9301 tccagtttca ggtactgtat caagcatctt cccaacaaaa catgcttttg gtattgtgac
     9361 ggaagcaggt cttgaagtat tggttcacat tggtttggac acagtaagtc ttgaaggtaa
     9421 accatttaca gttcatgttg ctgaaggaca aaaagttgca gcaggagatc tccttgtcac
     9481 agctgacttg aatgctatcc gtgcagcagg acgtgaaact tcaacagtag ttgtcttcac
     9541 aaatggtgat gcaattaaat cagttaaatt agaaaaaaca ggttctcttg cagctaaaac
     9601 agcagttgct aaagtagaat tgtaatatac ttgaggttgg aagctgtatt ccaacctctt
     9661 attttgggag aaaagaatga aatttttaac actcaatact catagttgga tggagaaaga
     9721 agcagaggaa aaattccaga ttttgcttga agatattctt gaaaaggact atgatttgat
     9781 ttgtttccaa gaaattaatc aggagatgac ctcgtcagag gtggaggtta atgaccttta
     9841 tcaagctttg ccagcagctg agcctattca ccaagatcac tatgttagac tcttggttga
     9901 aaagttatct gagcaaggga aaaattacta ctggacctgg gcctataacc atatcggcta
     9961 tgaccgctac cacgaaggtg tggctatctt gtctaaaaca cctattgaag ccagagaaat
    10021 tttggtttca gatgtggatg atccaacaga ctatcatact cgccgtgttg ccctagctga
    10081 aactgtagtc gatggcaagg agctagcagt tgccagtgtt catctctctt ggtgggataa
    10141 aggttttcaa gaagaatggg cacgatttga ggctgtcttg aaaaaattga acaagccact
    10201 tttactagct ggagatttta acaacccagc aggtcaggaa ggttaccaag ctattttagc
    10261 tagtccatta ggcttacaag acgcatttga agttgctcaa gagaaaagtg gtagctatac
    10321 tgttccgcct gaaattgatg gctggaaagg gaacactgaa ccccttcgaa tcgattatgt
    10381 ctttactacc aaagagttag cggtggaaaa tttacatgtc gtatttgatg gtaacaagag
    10441 tccacaagtg agtgatcact atggcttgaa tgctatgtta aactggaaat aataactgaa
    10501 aagaggttgg aacta
//
LOCUS       DAVHKZ010000058        10452 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000058 DAVHKZ010000000
VERSION     DAVHKZ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.058"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            54..407
                     /locus_tag="VVO74_002016"
     CDS             54..407
                     /locus_tag="VVO74_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU5695992.1"
                     /translation="MILRHLGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLPSMPYSAQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            622..738
                     /locus_tag="VVO74_002017"
                     /pseudo
     CDS             622..738
                     /locus_tag="VVO74_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
     gene            731..964
                     /locus_tag="VVO74_002018"
     CDS             731..964
                     /locus_tag="VVO74_002018"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695993.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            1092..1234
                     /locus_tag="VVO74_002019"
                     /pseudo
     CDS             1092..1234
                     /locus_tag="VVO74_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1371..2339)
                     /locus_tag="VVO74_002020"
     CDS             complement(1371..2339)
                     /locus_tag="VVO74_002020"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU5695994.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(2484..3107)
                     /locus_tag="VVO74_002021"
     CDS             complement(2484..3107)
                     /locus_tag="VVO74_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEU5695995.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSPFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(3089..3298)
                     /locus_tag="VVO74_002022"
     CDS             complement(3089..3298)
                     /locus_tag="VVO74_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5695996.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKNGNCQRRF"
     gene            complement(3323..3820)
                     /locus_tag="VVO74_002023"
     CDS             complement(3323..3820)
                     /locus_tag="VVO74_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU5695997.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(3893..5254)
                     /gene="radA"
                     /locus_tag="VVO74_002024"
     CDS             complement(3893..5254)
                     /gene="radA"
                     /locus_tag="VVO74_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU5695998.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(5268..5783)
                     /locus_tag="VVO74_002025"
     CDS             complement(5268..5783)
                     /locus_tag="VVO74_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU5695999.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(5785..6228)
                     /locus_tag="VVO74_002026"
     CDS             complement(5785..6228)
                     /locus_tag="VVO74_002026"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU5696000.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(6285..6382)
                     /gene="ffs"
                     /locus_tag="VVO74_002027"
     ncRNA           complement(6285..6382)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VVO74_002027"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(6415..6882)
                     /locus_tag="VVO74_002028"
     CDS             complement(6415..6882)
                     /locus_tag="VVO74_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU5696001.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            7162..7311
                     /locus_tag="VVO74_002029"
     CDS             7162..7311
                     /locus_tag="VVO74_002029"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696002.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            7453..7632
                     /locus_tag="VVO74_002030"
     CDS             7453..7632
                     /locus_tag="VVO74_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696003.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(7770..8726)
                     /locus_tag="VVO74_002031"
     CDS             complement(7770..8726)
                     /locus_tag="VVO74_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU5696004.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHYR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNTESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLRAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNTFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(8730..9062)
                     /locus_tag="VVO74_002032"
     CDS             complement(8730..9062)
                     /locus_tag="VVO74_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEU5696005.1"
                     /translation="MQQITEIIIAFATSFLTVAVGGIVKAVKDYLLRKGGEKAVIIAE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            complement(9066..9482)
                     /locus_tag="VVO74_002033"
     CDS             complement(9066..9482)
                     /locus_tag="VVO74_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEU5696006.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            complement(9492..9842)
                     /locus_tag="VVO74_002034"
     CDS             complement(9492..9842)
                     /locus_tag="VVO74_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696007.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTGEPKE"
     gene            complement(9845..10048)
                     /locus_tag="VVO74_002035"
     CDS             complement(9845..10048)
                     /locus_tag="VVO74_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696008.1"
                     /translation="MNTEQLNQALRMTISEISTTSTNSMITSNILSIQLDEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            complement(10142..>10452)
                     /locus_tag="VVO74_002036"
     CDS             complement(10142..>10452)
                     /locus_tag="VVO74_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEU5696009.1"
                     /translation="KYWMEQKSDRRLKENITDTAVKALDKINRLRMVAFDFIENKKHE
                     EIGLIAQEAETIVPRIVSRDPENPDGYLHIDYTALVPYLIKAIQELNQKIEKMEKTIA
                     "
BASE COUNT         3111 a         2436 c         1893 g         3012 t
ORIGIN      
        1 cctgatagag ttgttcacat cttatttcaa ttcactatag aaggaggaaa aggatgattc
       61 tcagacatct gggaattagc ccgaccaatg acttggttgc taagaaaatt ttcagcaacc
      121 cagaaatcac ttgtcaattt atccgcgata tgctggactt gccagccaaa aatgtgacta
      181 ttttggaggg aagtaacatt catgtcttgc cttccatgcc ctactcagcg caggattttt
      241 ataccagtat agacgtcttg gcggagttgg ataacggtac tcaagtaatt attgagattc
      301 aagtccatca tcagaatttt ttcatcaatc acttgtgggc ttacctgtgc agtcaggtta
      361 atcaaaatct tgaaaaaatt cgtcagcgag aaggtgatac tcactagatc tacaaacaca
      421 tcgctcctgt ttacgtcatt gctatcgtgg atagtaatta tttctcagat gacctggctt
      481 ttcatagctt tagtatgcgc gaagacacaa caggtgaggt attggcgatt accaacaatg
      541 gacaggaaaa ccatctggtt aagatggcat tcttggaatt aaaaaataca gagaaaccag
      601 caaagacaag gttcgcaagc catggttgga gtttttcggc aacaagccct ttacccagca
      661 accgcaacga gccattagcc aagcaaatca actgctggac tacaagagct ggtccgagga
      721 ggacaggaaa atgtttagtc aactacatat gcgagaagaa caagtcttgt tagcacagga
      781 ctatgccttg gaaactgcta gggctgaagg ccttgaacaa ggactagagc gtgggaaagt
      841 tgaaggaagg gcagaaagga aactttttgc cttcctagac atagtacgcc aaggtcttct
      901 gacttctgag gttgccagcc agcaattagg tatgtcagta tctgaatttg aggcactgtt
      961 gtaaaatggc tccataatat ccatagtggg taaatcccct atggatatta tggagcctat
     1021 tttgtgtaaa aaaaaaagtc ccatatgacc tataatgaaa agcgacaaaa caactcatta
     1081 gaaagaatca tatggaacaa ttacatttta tcacaaaatt actagacatt aaagacccta
     1141 atgtccagat tttaaacatc atcaataagg atacacacaa ggaaagcgtc gattcaaatg
     1201 ctatcactgt tcaaaaatga tggtcgctga aacttatgat gacgtacagt catatttctt
     1261 ttctttttat tatatcacag ttttaaatct agctttacta gattcaccgc tactatctat
     1321 ttattcggaa aaaagacgaa aaaacctgag aatcatctca ggcttggtca ttaaattttt
     1381 ttctcaatat cgaaaagtgg agaaagtggt cgtttttcat gaatacgtac gatagcatcc
     1441 cctaggagat gagcgattga aatctgctca atcttatcaa tcaaacgctc ttctggcaga
     1501 tagatggtat ccaaaacaac caatttctta atagctgatt tttggatatt gtccgtagca
     1561 ggaccagaaa gaactgggtg cgtacagctt gcatagactt caacagcacc agcttccgca
     1621 agagcatctg ccgcatgaca aatcgttcca gcggtatcaa tcatatcatc aatcaagata
     1681 caagtcttgc cttcaacctt accgatgatg ttcataactt cactagtatt catcttatca
     1741 acgctacgac gtttatcaat aatagcgata gatgttttca aaaattctgc caacttacga
     1801 gcacgagtca cccctccatg gtccgggctg acaaccacat agtcagaacc aaccatacca
     1861 cgacgctcaa aataatctgc aatcagagga gcacccatca aatgatccac aggaatatca
     1921 aagaatcctt gaatttgcgc agcatgcaag tcgatggtca ataaacgatc cactccagct
     1981 acttcaagca tatttgcgac aagttttgaa gtgattggct cacgcgctct cgcctttcta
     2041 tcctgacgtg catacccata gtaaggcatg acaacattga cagattctgc actcgcacgc
     2101 ttcaaagcat ctaccataat caaaatttca agcagattgt catttacagg cgaactagtt
     2161 gattgtaaga taaagacgtg tttcccacgg attgattctt caatgttgac ctgaatctct
     2221 ccatctgaaa attggcgaac acttgatttc cccaactcta tcccaatctc ctgcgccaca
     2281 cgttctgcca attctttatt agaagaaagg gcaaacagct ttaaatcaga aaaagacatg
     2341 atttcctccg gtatatatgt atagcttgtg cttttcacaa gattttccat ctaccattgt
     2401 agcgcttttt gcactatttt tcaatcaaaa ataaaagaag ggcaccatat ttgtaccctt
     2461 gcatcattct tttgaaaaat attctaggtc atcaactcat tgtgtttctc aacaaagcaa
     2521 taagcatgat aaaaaccata gagagcaata gccgtaacca ctggaatcgc taaaggcaac
     2581 tctgtttcca actccacaaa aggagagtta aacaagaagt gagttcccaa ggctaaacct
     2641 agaaaaataa ggccctgttt cttgccaacc ttctgtcctt tataggctct gtaaagcaag
     2701 taaacaccta ctacagctag acctgaaaaa gtccagtgag aggcaattcc tgagatgata
     2761 cgctctaaaa ttcgcgaaat agtaaagtca aagccctctg gcaaatccgt acgaatataa
     2821 ccaatatcct caatcatttg gaatcccaaa ccggaagcaa ttccaagtaa aaacaaagat
     2881 tttaattttc gcacaggaat caaagccaaa acaaaaacaa gtggcaataa tttcaagggt
     2941 tcttctacca aaggagccac aatagcactt tcaaaggcat ttaaaaatgg actatctggg
     3001 aaaagaaccc ccagtaaatc atggatataa gtattagcaa aactagacaa ccagcctgaa
     3061 aggaacatcc ctcccaataa agacagaatc aaaaccttct ttggcaattc ccatttttcc
     3121 caatacggaa gagaaaataa agagccggaa tcatgtaaaa gagagctaga aagatagaaa
     3181 ctcccattag tccatattcc gcacctgacc tcgaaccgtc cgtatagtag atggtttcat
     3241 actgtaaacc aatacatagc aataaaataa aaataaataa aatactgctt ttcttcatac
     3301 actttctttc taaatgaagt atttataatt ctacgactgt catacttcct gtatcaacat
     3361 tgtaaatggc accagagata atgacatcgt ctggtattag gggagactcg ataagcagtt
     3421 gcatatcctc gcgtacactc tcttctatat cttggaaggg caagaagtcc tggtctgaca
     3481 catctacacc taattcctct tttaaatact cctgaaaagg ttcattttca aaggtctgag
     3541 caccacagtc tgtatggtgc aataccacaa tctctcttgt ccccatttgt tgctgggaaa
     3601 taactagcga acgaatcatg tcttcagtca ctcgaccacc tgcattccgc aagatatgag
     3661 catccccaag tgccaagccc agagcttgcg caacgtgcag acgagagtcc atacaggtca
     3721 caatagctac tcttgttttg ggtttaagtg gcagatttaa ctgcccatgt agggcaacat
     3781 aagcctgatt ggcttgcata aactgttcaa aatacgacac gattccctcc ttgaaaattt
     3841 gatagtcaaa tatttctcct atcttatcat ttttaagaga atttgtcacg gattatgcaa
     3901 agaccttttt caagacttcc tgaatcgttg tcacgccaat gacctgaatt tccttaggca
     3961 gagtgattcc tgtcaaggaa ttcttaggta cataaatctt agtaaagccc agtttagcag
     4021 cttcgttgat gcgttgctca atacgattca cgcgccgaat ctctcctgtc aagcccagtt
     4081 ctccgacaaa acattcctga ggattagttg gcttgtcttt gtagctcgaa gcaatagcaa
     4141 ctgcaacagc caagtcaatc gcaggttcat ccaatttaac accaccagca gatttgagat
     4201 aggcatcctg attttgcaag agaagccctg cccgtttttc caaaacagcc ataatcaagc
     4261 tagcacggtt aaaatcaagt cctgtcgtag tacgcttggc atttccaaac atggtcggtg
     4321 ttaccaaagc ctgaacctcc gccaaaatcg gacgcgtccc ttccatggtt acaacgatgg
     4381 aggaaccagt cgccccatcc aaacgctctt ctaggaaaac ttgactcgga ttgagtacct
     4441 caaccaagcc gcccgactgc atctcaaaaa tcccaatctc attagtggaa ccaaaacgat
     4501 ttttgaccgc tctcaaaata cgaaaggtgt ggtgacgctc cccttcaaag taaagcaccg
     4561 tatccaccat atgctccaac atacgaggcc cagccaaggt tccttctttg gtcacatgac
     4621 ctacgataaa gatggcaatg ttattggtct tggccaactg catgagttca gcggtcactt
     4681 cacgcacctg agaaacagac ccctgcaccc ctgaaatctc aggagacatg atggtctgga
     4741 tggaatcaat aatgagaaag tctggctgga tacgctccac ttctgcacga acactctgca
     4801 tattggtctc tgcatagaga taaaactcac tatcaatatc acctaagcgc tctgcacgta
     4861 gtttaatctg ctgggcagac tcctccccac tgacatagag aactgtcccc acttgggaca
     4921 actgggttga gacttgtagg agaagagttg atttcccaat cccaggatcc ccaccgatga
     4981 ggacgagact tcctggtacc actccgcctc caagcacacg gttgaattcc tccatctccg
     5041 tcttggttcg attgacattg atggaagtca cctcagctag tttcatgggc ttggttttct
     5101 cacctgtcaa ggacacacgc gcattcttga cctcggcaac ctcaacctct tccacaaaag
     5161 aagaccaaga cccacagttg gggcaacgtc ccagatattt aggggaatta tacccacaat
     5221 tttgacatac aaatgtcgct tttttctttg cgatgacaaa cctctttcta tatctctaac
     5281 tcacactcaa tcacttggca aaaatcaatc ttctcatttg gcacaaactg gcgcatgagc
     5341 attcgatgag caacaactac cacagtctga tgttctcgat acttagacat acattctaga
     5401 aaccgagact tcatttccgt agctgtctca tattgaatag gactattagg aagcaactcc
     5461 cccttgtttt ctaaaaacag tcttctagct gtttcaaaat tttctattcc tgttttatag
     5521 acctgccatt catgtaataa aggctctact cttaaaggaa gacccgtagc acagaccaca
     5581 tacgaagccg tttctaaagc tcttgtgact gcagaagata cgattatttc agctgacgag
     5641 agtaaaggat ttttgctcaa tttctggact tgctgccgtc ccatctcaga caagggtgcc
     5701 aaatctatcc caaatcctat ataagaacgc tcctctaact cacggtaatc tggctcccca
     5761 tgacgtacaa agataatctt cattctagtg ccctgtcgat ccaaatccac cagttcgaac
     5821 gccatcagct gcatctccat ctgcaattaa gaaagtagca aaaacagcct ggacaatacg
     5881 ttccccaact tcaagaacaa cctcttgatc tgtgatattc ttcatctgcg caaaaatatg
     5941 cccttcattt ccaggatttc cataataatc cccatcaatg accccaactg agttaattaa
     6001 aaccaagccc ttcttacgag gatttgaaga acgatcatag aggtagagaa cctcagtcgg
     6061 ctgcatataa gccttaaccc ctgtcggaac caagacaatc tctcctggcg caacaactgt
     6121 acgcacagca acctttaagt cgtaaccagc cgcatgcgct gtctcacgct tgggcaataa
     6181 attttcatct gtaaaactcg aaaccaattc aaaaccacga attttcataa ttttctcttt
     6241 tctattatca tttattctag attattctat cttatttatt cggaaaaagc acgaaaaaaa
     6301 gagcacacaa ttcaaatcgc ttagggctgc tggattcctc ccctgacccg cttcacgcag
     6361 aactgttgct ccactattta ttatatcaca ttcctattca ttttaaaagc aaaattattt
     6421 tttccgtcta tttctaaaaa aatcctgcat gatagctgcg cattcatctt ccaaaattcc
     6481 tatttcaacc tccacacgat gattgagacg ctcatctgtc aagatattgt acaaactccc
     6541 agcagcgcca aatttctggt ttttagcccc atagaccaca tttggaatgc gggcaagccc
     6601 aatcgctcca ctacacatga cacaaggttc aatggtcaca aaaagtgtgc aatccagcaa
     6661 gcgccagctc tcctcactca agttcgcatc ctctatagcc ataatttccg catgcataac
     6721 cgctcgctgt aattcctcac gcgcattatg cccacgacca atgatttccc catctttgac
     6781 aatcacacaa ccaattggaa tttcatcgtg ttcaagagca atctcagcct ctctcaaagc
     6841 ctccctcata aagacttctt tttcttcaag cgtataatac atctcttttc tcttttccta
     6901 cttatcgatt ttattattat atcatgaatc ccaacacaaa aaaagccacc gaatgcggtg
     6961 actctatagg gagattatta tgaaaaaggt aaaataaaac cttattaaat caatgctttt
     7021 ggagggtgcc ccctccaact ccccgacctc tggacaaggt ctattttttt tgaaaaaatt
     7081 aaaaaaactt catcaaaacg cttgactttc tcggtgtacc gtgatataat ataatcaaga
     7141 taaggaaagg gggtgatgaa gttgaacaaa gaagattggc tcaggttact tgaaaaggca
     7201 atagacaata ttcctgaaac ggtaactgct atcgcaagtc tagtgaccgc aataacggtc
     7261 gcaaggcaaa acaaaaagcg taaaccgaaa tcccgtcaaa gaaaaaggta aacgctaaga
     7321 ggttggggcg aaagcccctt acacctctat tttatcaaat ggaaagagga aatgcaatgg
     7381 ttagtgcaat agctattttt ataattgcaa tcaatgtata tatttatcta aaaaataaaa
     7441 aggacaaata agatgagaga agttattcaa gaattgttag acagttcgat gtctacatct
     7501 gctatttccc aaggtgctgg agttccatgg actactgttt ctgacctcag aaaaggaaaa
     7561 acaagcatgg acaaaatggc acttctcaca gcagaaaaac tttatgaatt tgctacaact
     7621 gataagcagt gatttcggtc actgttttta tttttgacaa aacacctctc tattcttcaa
     7681 gaaaacgctt ttttaaagaa tcagagcaaa taaaaaaccg caagcctaag cctgcggtga
     7741 aagaacaatt tagaaagttt cctttctatt tatttaactg taatcaagcc atctggctct
     7801 actgtgaact ctggcttgtc tgccagtgtt ccgtctggtt tgaggtagta ccagcctgtt
     7861 ccgtccgctg actggataaa ggtatttgat accatggcgc cttctttagc gtctaagtag
     7921 taccaagtgt ccttgtactt gacccagcct gtcttcatgg caccttctac atcaaaatag
     7981 taccacttct cagcgatttt cttccagcct gtagccattt cgcctgattg gtcaaagtag
     8041 taccaattac cgtctgtgtg cttcttccag cggtctgaaa gcatatagcc tgagccatcg
     8101 aaataatacc aggtaccgtt gattttctca aacttatctt ttggataaga gccgtctgag
     8161 tgtacgtacc agtagccagt gccatttttc tgccagcctg ttgcagctct caagccgttt
     8221 tcgatgtctt gcttaaactg ttcacggcta atgccccaac ttgcaagata tggatatgga
     8281 tccacatggt ctgagtggtt gtttggttgg ttattggtac agtattcatg cgtcttgata
     8341 cctgccaagt cgtctgtatc aagagtcttc ggcaagcctg cttcgtccgc tagattgcgt
     8401 agcaattcga tatagaggcg gtagtcagcc ataaactctt ccttagttga atggctttca
     8461 atcagttcaa ccgctgcgta actctcagta ttccaaccgc ccccaacatc ccaacttccg
     8521 ttgttcacag gacctacttg catgacacgg ccgtttccga caacatgtga aaagaaccct
     8581 agttcagggt cctttctata gtgataatcc gcttcattct gtacggttga gttgcggtta
     8641 cctgttgagt gagcatgtac ttgtcgataa ggctgcaccc caacctgggg caagcctgta
     8701 cgtagtctgt ttctatcgat atccattccc tatcgtcctt tccatgcgtc attcatctgc
     8761 ttcactgctg actctacgaa ggtgtctaag tctttgtcag tcatgctaat attgtatttt
     8821 gtaagctcag cacggacttt agcgcgagcc tgtgccagtt tttcatctcc cttgtagcca
     8881 gtttcagcag ctacctgctc cacggcattt actgcatttt tagctagaat ttcagcgatg
     8941 atcaccgctt tctctccgcc tttacgcaaa agataatctt ttactgcttt tacaataccg
     9001 cctactgcta ctgttaaaaa gcttgtcgca aaagcaatga tgatttcagt aatttgctgc
     9061 atttgttatt ctcctttttt cgtgtcatca tctttttcaa gtaatcgctg aaatactttt
     9121 acaatcggct gaaaaagagt aacatttcct tttaatttgc gataattttc aatgagagat
     9181 tgaaaagtaa atgcgatgta cccgagatag attgagtgca agaatacaaa acctgtcttt
     9241 tcaggcaaca aaacggacgc cggaatgagg atcatcagta agagaacccc tgaaatctta
     9301 cgaaggagcc cgttaatgcc gattttgctc ttgtactcga tgtcaggatt gataatcgcc
     9361 gcaatcgtcc ctgtcacaaa atcaatgatt tccattgaga caatcagtgc tagagcgtac
     9421 aagaccaaac catcttcagt ctgtacgaca cttcttagaa aattgaaaaa ttcaatttgc
     9481 atacacatct cctattcttt aggttctccc gttggatccg tccagtcagg attgccctct
     9541 gcatcaaatt tcatgatata gaattcatga ttcaacagaa cggcgacgtt gattgttgcg
     9601 attgtaccac cccactggtt gaacgcccaa acggtttcaa catccttgag ttggcgacgg
     9661 ccatttacga tcacaggacg tttttgaaca tcacgataca tatagaagtc atcgcttaca
     9721 ttcttgcaac gaatgaactc tccattttct ttcatgtagc gcaaagcact cgcaagatca
     9781 aatggttctg tgatttttgt aaggtctagt aagttatctg tgttttgaat tgtttctgcc
     9841 atgtctattc tcctttgtct gctggtttag tttgttcatc aagcagagct tccagctcat
     9901 ccactcgtgc ttgaagtctt tgattttctt ccctttgctc atccaactga atactcaaga
     9961 tattacttgt aatcatcgaa tttgttgaag ttgttgatat ttcactaatt gtcattcgta
    10021 aggcttggtt aagctgttct gtgttcattt tctaagttct ccaatctgtg tgttcgtttt
    10081 ctattttcaa gagcaagctc ctgaattgct ttaagtgcga tattggtcaa catgttgtta
    10141 ttcatgctat tgttttctcc attttttcta ttttttgatt taattcttga atagccttga
    10201 ttaagtaagg aactaaagcg gtatagtcga tatgtagata gccatctgga ttctcaggat
    10261 ctcgtgagac aattcttgga acgatggttt cagcctcttg agctattaga ccaatctcct
    10321 catgtttctt attttcgatg aaatcaaatg caaccattct taatctgttg attttgtcca
    10381 aggctttcac agctgtatct gtgatgttct cttttaagcg tctatctgat ttttgttcca
    10441 tccaatactt ca
//
LOCUS       DAVHKZ010000059        10169 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000059 DAVHKZ010000000
VERSION     DAVHKZ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10169
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.059"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(162..1925)
                     /locus_tag="VVO74_002037"
     CDS             complement(162..1925)
                     /locus_tag="VVO74_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU5696010.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            complement(1934..2524)
                     /locus_tag="VVO74_002038"
     CDS             complement(1934..2524)
                     /locus_tag="VVO74_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU5696011.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            complement(2622..3113)
                     /gene="rocS"
                     /locus_tag="VVO74_002039"
     CDS             complement(2622..3113)
                     /gene="rocS"
                     /locus_tag="VVO74_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU5696012.1"
                     /translation="MSIEMTVSEIAEILGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            complement(3190..3882)
                     /locus_tag="VVO74_002040"
     CDS             complement(3190..3882)
                     /locus_tag="VVO74_002040"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU5696013.1"
                     /translation="MKIGIIAAMPEELAHLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            complement(3899..4213)
                     /locus_tag="VVO74_002041"
     CDS             complement(3899..4213)
                     /locus_tag="VVO74_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU5696014.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            complement(4225..4770)
                     /locus_tag="VVO74_002042"
     CDS             complement(4225..4770)
                     /locus_tag="VVO74_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU5696015.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            complement(4780..6159)
                     /gene="glmU"
                     /locus_tag="VVO74_002043"
     CDS             complement(4780..6159)
                     /gene="glmU"
                     /locus_tag="VVO74_002043"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU5696016.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRCRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPRNQ"
     gene            6293..7093
                     /locus_tag="VVO74_002044"
     CDS             6293..7093
                     /locus_tag="VVO74_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU5696017.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQHPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSIWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            7188..8030
                     /locus_tag="VVO74_002045"
     CDS             7188..8030
                     /locus_tag="VVO74_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU5696018.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYSLNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNTGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            8030..8512
                     /locus_tag="VVO74_002046"
     CDS             8030..8512
                     /locus_tag="VVO74_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU5696019.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            8512..9132
                     /locus_tag="VVO74_002047"
     CDS             8512..9132
                     /locus_tag="VVO74_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU5696020.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPADRILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(9385..9480)
                     /locus_tag="VVO74_002048"
                     /pseudo
     CDS             complement(9385..9480)
                     /locus_tag="VVO74_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            9893..10169
                     /locus_tag="VVO74_002049"
                     /pseudo
     CDS             9893..10169
                     /locus_tag="VVO74_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3127 a         2153 c         1769 g         3120 t
ORIGIN      
        1 ataagttata gtgtagcatt ccaacttcaa agcactataa agtaaattga aacaagaaca
       61 atacaaacaa ttctcgtaaa cggattgcaa ccacaaaaaa gcaagcattc acaagaatac
      121 ttacctatca tgggaggaac aaccgttcct cttttttatt actaaaattc aaagaattcc
      181 aatgcttttt tcaagagcaa atccgtatat tctggatctt cttgggctac ttctatttcc
      241 cgctgaactt tttccaaatc atctgtaatc actccatcta ctcctaagtg aagagatttg
      301 ctgatagctt ctgaatcatt gacagtccag acataaagtt tctgatccgt tgtccatagt
      361 ttgcttacaa aatattcatc caaggttgag tactccatag tatatcctgt cgctcttgtt
      421 ttaggaaaga cagaattgta gggcatgatg aaataaactg gcagttcggc atcatactgt
      481 cttacttttt cgacaacatg gtagtctaaa gactggattt gatgtccata aatcttgagc
      541 tttgcagcat aacgggctaa aaagcggttc atcatgtctg gactatcttt tttactggtt
      601 ttaatttcaa ttagtaattt ttgaccaagt tcgttggctc gactgagata atcttcaaag
      661 cttgaaattt tagtctggta gccattttca aaaatatcaa tccctttaag ctcctccaag
      721 tttaagtctt gaggactttt attgatacct gctagatttt tcaagttagc atcatgcatc
      781 atgacaaact gcccatcttt tgtttcctgc acgtccgtct ccaccaagtc tggtttgagt
      841 tgtgctgtag tttccaagga ctctactgta ttttgaatcc catttgcatt ggaaacccct
      901 cggtgagaaa taagttgagg tagatgaacc atgggagcct ccagataaat ataaccttct
      961 aaggcaaaga aaagactggc acaagtcatg acaccccatc gcacgatgtg atctttttct
     1021 ctcctaggaa gcatatccag ctcctttcct gtcaaaaatg aaacaaattt aaccaaaaaa
     1081 taagtcagag ccatataata gagattttta atcacgacaa aattcaaaat accaagaatc
     1141 agagactctc tctgagtgat atcatctacc aaagtttgag ccaataataa agggatcaaa
     1201 ggaagataaa ataataaatg tgctttgagc aagatgtaaa ataaattcca agcataaaaa
     1261 gtaactctct tcttggtttt ctccaagcta aacatcactg cttctcgaac agtcagctga
     1321 tcatatacaa tcttcggaag ggcaaacatc aatctgacag agacatagag aaagataaga
     1381 gatagaagta ggatgctcag ccaccacatc caatatctat cttctaaata agcttggata
     1441 aactctggaa tgacgatttt attaagataa taaatcttca gcattttccg tataaaagga
     1501 aacagcatag ctatatagaa aaagataaac aaggctttag cgcaagttag ctttttcata
     1561 aatccaaaac tttcatggaa aaccttgcgg atatactcaa ttagccttcg cttttcatta
     1621 tagaggagat gacgagcacc aataaagagg agtcctattt gaaaataagc aaccagaagg
     1681 ttaattacaa tcaaggctaa aaaagctaga ctaatcaatg gagaatgagt aaggatggct
     1741 aagacattgt tataggaaat aaaaagataa cctgtctgat ctaataagaa gctagccaac
     1801 catgaattga atggtaccca caaatactcc actatcataa aaatcaagaa aaatagaaag
     1861 aggattttat caagattgag gtaaatctgt ttaagaccca attttttagg tttttcaggt
     1921 ttcataggca ctcctagtca aataattgag acaagtccaa gccaccaaaa ggattgtttg
     1981 ataagctact ttctgtctct aacaattccc tagcttgatc cgactctaag aaggattcgt
     2041 aaacacgcgc cgtcatccga gcatcctcta aactattatg agactgacct tgaaatccaa
     2101 gaaatgaggc aacagtttgc aatttgagat tggcaatacc atgtaaatct gaactccgac
     2161 gttcaaaagc ttcatcatac aaatccacct tgtactgttg gctatagtct aaaccatgct
     2221 ctgctaaaat aggtaaatca cttttagcag cattgtagcc tatcatcagc aaagaaccca
     2281 caaactcttg gaattcttct aagactttct caactggagg agcatctttt aaggtctcag
     2341 ctgtaatccc ggtcaaacca ttgataaagc tttttagagg gacgctggta tgaacatagg
     2401 aatcataggc atcgatttcc cgaccatctc taaaacgcac tgccgatact tgaatcaagt
     2461 gtgtttgtcc ttcgtgctga ttaaattcta agtcaaaagc aatgtaatct tctaatcgtt
     2521 ccattctgta cctctcctct actgtctctg ttctaatcaa ctatactatt cacaaacaaa
     2581 agaagccatc aggttagcat ttaacctaaa cagctccttg attatcctcc aaataaacga
     2641 gcaaaaaagc cttttttagt ggattggact tcttcttttg cttggtccag ctctagctta
     2701 agattttctt gatccttcat ggcttgaagg gtcaattgtt gttgctgatc taattgtttg
     2761 tctttctcag caatctgacg gtctttgata cgcatctgct cgtctttttc tgataactga
     2821 cgatccttgg cttttaattg ttcataaaga cgaagaattt ctgcattctt ctcatccact
     2881 agaatctcca tcagttcacg ttgtttgaca tcttcactga caggttcatc ttcaaaaatc
     2941 gtttttttat agatttcttc tagcttaatc aagccacttc tggtaacaac tgttacccct
     3001 ttgtcatttt tatctgtgtc ttcttctggt aattctttga cacggttatt gattgcttgg
     3061 cgagataatc ctaagatctc tgcaatctca ctgacggtca tttcaatact cataatatcc
     3121 tctgaaacgt tttctagctt ttctttactt aaatcttatc ataagctaga aaaactgtca
     3181 aatttccgct taatctaaag ccttcaaaaa ggccaacaag acttgggcag agcgacgtcc
     3241 agcttcgata ataaactcat caaaaaagat gtttgcttca tggttggcat tgtcactcat
     3301 agctctgatg actaagactg ggagattgag ggcatgcgct gcttgagcaa tagctgcccc
     3361 ctccatctcc acggctaaaa cttctgggaa atgggactta atcgcttcta tcttgtcatt
     3421 tcctgcaaca aaactatctc ctgtagcaat caaaccaaga tgccagtttt ggtccaattg
     3481 agataaactc tcttggattt gagcaacaaa ggttttgtct gattcgaaat aaagcggttg
     3541 ttgcgccatt tgtccataag catagccaaa agctgtgaca tccacgtcat gataggctaa
     3601 tttgtcagca atcacgacat ccccaacagc gataccttct gctactgccc cagctgaacc
     3661 cgtattaata agggcatcca cctggaaatg atcagccaaa atcgccacac tcatagcaga
     3721 catgacctta ccaattccac tttctacaag aacgacttca tgagaagcaa tggttcctgt
     3781 atgataggta ttccccaaaa caacttgctc ctgggcattg tctaaatgct ggaccagatg
     3841 agccagttct tctggcatag cagcaataat tcctattttc atttcaattc cttttctatt
     3901 acaaaagttt cattgctaaa acaagcaaaa tcaagagaaa gatgaccgcg aataagattt
     3961 tattcaactt agaattgaag acatttctct tggtattttc aatgcgacgg cttttatgaa
     4021 tagatggttc gacctgaatc ttcaaggttt cctggctaaa accatgatcc ttaggattgg
     4081 cataaccaaa acgggaagaa gaggttggta aaatcttagt ttcctcatta tcatccagca
     4141 aaggaggacc tgaaattttt tcgcctctat tagctctttc aatcatttca tccgttaata
     4201 aagatttacc catactgacc tcctctattt tttctgcaac tcccaatact gaacagccat
     4261 aattgtcttg gcatcacaga tatgacctga ttggattaat tctttcgctt cttctaagct
     4321 cacttcaagg acttccaagg tttcatcctc atcctgcgga cgcggatttt ccacttttgt
     4381 caaatcgctt gctaaatata gttttaactt ctcattacaa aagccaatag ctgaataaaa
     4441 atcgtacaag agttctaatt tccctgtata ggctgtttct tcctctaatt cacgaagggc
     4501 agctgccaca ggggctgtgt tttctcctac ctccaatttt ccggctggaa tttcgtaaga
     4561 gacagcctcg atagctttgc ggtactgctt gaccaagata agtttttgtt catccgttac
     4621 tgctaaaaca cagacagccc cattgtggaa aatcaaatcc cgttgggcag ttcccttgcc
     4681 ttctggtaat tcaacctgat cttggaccag tttaaatatt ggtccttgat agatttcttt
     4741 tcggctaagc gttttttctt caaactccat gataggctcc tactggttcc taggatgatg
     4801 aggaagacgt gttgcatatt cgtctttatt gatctgacga ccgcgaccaa tagcaatagc
     4861 atctgctggc acgtctttag taatagttga accagcacca acgagggaat tgtcaccaag
     4921 ttctactggt gcaataatgg ttgaatttga accaacaaag acattgtctc caatgactgt
     4981 cttgtatttg tttttgccgt catagttgac tgtaatagtt ccagcaccga aattaacgtt
     5041 gcttcccact tcacagtttc cgatataagt caaatgacca gccttggtat tctcaccgat
     5101 tgaagatcct ttcacctcaa caaagttacc aatatgaact tgggcaccca gacttgaatt
     5161 tggacgaatg tgagcataag gaccgactgt cacaccgtct gcaacactac tttcctcaat
     5221 catagaattg gtaatgaccg ctcctgctcc gatagtgctg tccactacat aagtaccgtt
     5281 tgtcaaaaca gtctcagcac caattttcgt ttgccctttc aaggtaacat tggcttcgat
     5341 ttgaacttcc ggagcaatct caacatcaat atcgatataa gttgcttctg gattgacaaa
     5401 gctaacacca ttgaccatgt gtttatgatt gatgcgacaa cgcataactg actcagctgt
     5461 cgcaagcgcc acacggtcat ttaccccaag actttcatca aaatctttca aagtataagc
     5521 gccaactttt tcaccagttt cacggaaaat accaatgacg tctgtaatat agtattcgcc
     5581 ttgagcgtta ttggtattga tatttttcaa agcctcaaac aaacgctcgt tgtcaaagac
     5641 gtatgttcca gtgttgattt ccttgatttg cttttcaaaa tctgtagcat ccttctgctc
     5701 aacaatacga agaacctcag cattgtcatt acgaacaatt cgtccatagc caaaaggatt
     5761 atccgtttca gcagtcaaga tagtggccac atttttatga ttgatatgga aatcaatcaa
     5821 gtttttcaag ctttcaccag tgattaaagg agtatctcct gcaatgacca aggtgtgtcc
     5881 tgacaaacct tctaagatag gctctgtcat cataactgca tgaccagttc ccaactgttc
     5941 agattgagtc acaaattctg tctgtccagc caagacctcc tcaaccaatt ctgccttgtg
     6001 tcctacaact gttactgtct tttcaggttg gatagctccc acactacgga aaacatgttc
     6061 caacatagaa atacccgcaa ccttgtgcaa aacttttggc aaatcagatt tcatgcgagt
     6121 ccctttaccc gctgctaaaa taatggcaaa atttgacata atcttctctt tcctgtagaa
     6181 attccctttt attataccat atttcaaatc attccgcact cttgaatgaa aaaatgctct
     6241 aaagtctctt ccttaaccca tttttttgat ttttagggta gaattataag atatgagaaa
     6301 acaaattcat ccacttattt tatttagttt tttggggatt atgatgttca ttttaatcat
     6361 caatcgccca cttaatgaca accaatcgtt taaaacaaaa tccaatatag cacagattga
     6421 agcacaggct ttgaaacact tagacaaacc gattattgac ctctctggct ggcagcatcc
     6481 tgaggaaatc aactacgatg ccctctcaca aaatatttca ggtgctattg ttcgtgttca
     6541 cagtggtgct caaacgacaa aagaaaatga tgcttcattt atcaatggaa tagacaaggc
     6601 ctataagagt catatcactg aacttcaaaa gcggaatgtc ccagttgctg tctacgctta
     6661 tgtagctgga aaaagtgtcc aagaaatgga aaaggctgcc gaagttttct acaatgctgc
     6721 ctctccttac agccctagtt actattggct tgacgtggaa gacaaaacca tgtctaatat
     6781 gaacgaaggt gtcgaaaact ttcgagcaaa actagcatca ctaggtgcta aaaacatcgg
     6841 catctacgtt ggtgtctact tcatggaaga acacagtatt gatacaggca agtttacctc
     6901 tatttggatt ccgtcctacg gctcagactc aggatttttg gagagcagtc ctaaaactga
     6961 tttagattat gatattcacc aatacacatc taaaggaaaa attgccggct ttgaccacga
     7021 tttagatatc aacgttatct ctcccttaaa aaataaagaa gaaacctttc gaaaactttt
     7081 tttaaaacct taaaagcatt tgtttatcat ttgctttttc tttttgtgtc tgattgtgat
     7141 acaatatagt aaggattttt tgaaatagaa atagttggag gaaatatatg ctctcatggt
     7201 tagcacgcgt tattaaagga attgtgattg ctcttggatt tatcctaccg ggaatttccg
     7261 gaggggttct agcagcaatc ttaggaatct atgaacgaat gattggcttt ctggctcatc
     7321 cctttaaaga ccttaaagaa aatgttttgt actttattcc agttgccatc ggtatgcttc
     7381 tgggaatcgg cttattttcc tacccgattg aatacctgct tgaaaattat caggtctttg
     7441 tattatggag ctttgcggga gctattatcg gtacagttcc tagcctcctc aaagaatcaa
     7501 ctcgagaatc tgaccgagac aagattgatt tagcttggtt atggacaacc tttatcattt
     7561 ctggattagg actctattcc ttaaattttg tcgttggaac cttaagcgcc agctttctta
     7621 acttcgtcct agcaggcgca ctattggccc ttggcgtctt ggttcctggc ctcagcccat
     7681 cgaatttact tttgattttg ggactctatg ctcctatgtt gactggtttt aaaacttttg
     7741 atctcttggg aaccttcttt ccgattggaa ttggtgcagg tgcaactctc atcgtttttt
     7801 caaaattgat ggattatgcc ttaaacaact accactcacg cgtctatcat ttcatcatcg
     7861 gtatcgtcct atcaagtacc cttttgatct taattccaaa tacaggaaac gctgaaagta
     7921 tccaatacac aggactttca cttgtcggtt atgtcatcat cgccttcttc tttgcgctgg
     7981 gaatctggct tggtatttgg atgagtcaat tggaggataa atataaataa tggcaaaaaa
     8041 agttaaaatc aaaaaaacat tggtggaaca aatcctatct aaagcagcta tccctcatca
     8101 ggggattcaa atcaatgccc tagaaggaga gcttcctcaa ggttatgaac gagatcagat
     8161 tttcaaaacc ttggcgcttt tgggagacaa gaccggaccg attatcggaa ttgtccctat
     8221 cactcagcac ttgtctgaaa agaaactagc taaaatttct ggcaataaaa aagtgagcat
     8281 gattccacaa aaggacttag aaaaaacaac tggttacatt catggagcca ataatcctgt
     8341 cggaattcgt cagaaacaca attatcccat ttttatcgat aaaattgctc tagatttgga
     8401 tcgaatgatt gtctctgcag gcgaagtcgg acacagcatt atcgtcgcgc cacaagactt
     8461 ggctagcttt gtaaaggcag actttgtaga tattttggag gacatcaagt aatgaaactc
     8521 tactttgtcc gccacggtcg taccctctgg aaccaagaag gtcgttttca aggtgctagc
     8581 ggtgattctc ctcttcttcc tgaatccatt gaaaccctaa aacgacttgg ccagtatctc
     8641 aaggaaattc cttttgatca gatttattca agtgatttac ctcgagcggt caaatctgct
     8701 gagattatcc aaagtcaact ccataccccc tgttctttag aaatcgttcc taatctccgt
     8761 gaatggcaac ttgggaagtt agaaggtttg aaaattgcaa ccttggaagc tatttacccg
     8821 caacaaatcc aggcttttcg ttcaaatctt gctcaatttg acactcgaat gttcggagcc
     8881 gaatccctct atagtacaac tcagcggacc atccaattta tcaaatcatt aaaagatagt
     8941 ccagctgatc gtattctaat tgtcggacac ggcgccaatc ttactgccag tcttcgtact
     9001 ctcctaggct ataaagaacc acttcttcgt aaagatggcg gtctagcaaa tgccagcctg
     9061 accattatag aaacccatga ttttgaaaca ttcactctca atacttggaa tgatacttct
     9121 tatcaatcat aattatagcc tagccttctg aactagaacc ataggagata tagtcagttg
     9181 aaacaaaaat aagacaaaag aaccttgtaa aaaggtattg caacttgcca ataccttttt
     9241 gatatgaaca cgtgtcttct caacaggatt gtagagcaaa atgaaataag aactgaataa
     9301 tatgatttga gaatttaaat caatttataa gaatgtttta gaagcagtta tgtactattt
     9361 tagattcact tttctatact aagatgagta gggaggaaaa ggtaaaagtt tatgcccaaa
     9421 ttcttcacat aagaactcta gcttacccat tctatggaat cttgcattat ccattaaaac
     9481 ttccagactc atacccttct aaaatctatt caaaccacgt cagcttcaca ttatatatgt
     9541 tggtgacctc acaagtttta tctacaacct caaagctgtt ctttgagcag cctacagcta
     9601 gcttcctagt ttaatctttg cttttcactg agtatcaagt taaaaaaatg aggctggtca
     9661 aaaagtcttt aaaataaaaa acgcatatta tcaggtgtta aatgaactgc accccaaaag
     9721 ttagacagaa aaaatctaac ttttggggtg tttttattat gaaattaact tatgatgata
     9781 aagttcagat ctatgaactt agaaaacaag gatatagctt agagaagctt tcaaataaat
     9841 ttgagataaa caattctaat attaggtaca tgattaaatt gattgatcgt taatgttgga
     9901 acaggcattc aaagagaagc actacgagaa tacgattctc catagtgacc aaggctggca
     9961 atatcaacac gattcttatc atcggttcct agagagtaag ggaattcaag catctatgtc
    10021 acgcaaggga aacagccaag acaacggtat gatggaatct ttctttggca ttttaaaatc
    10081 cgaaatgttt tatggctatg agaaaacatt taaatcactt aatcaattgg aacaagccat
    10141 tatagactat atccccaatt atgcacccc
//
LOCUS       DAVHKZ010000060        10050 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000060 DAVHKZ010000000
VERSION     DAVHKZ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10050
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.060"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(1..103)
                     /locus_tag="VVO74_002050"
                     /pseudo
     CDS             complement(1..103)
                     /locus_tag="VVO74_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(165..614)
                     /locus_tag="VVO74_002051"
     CDS             complement(165..614)
                     /locus_tag="VVO74_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU5696021.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(616..1374)
                     /locus_tag="VVO74_002052"
     CDS             complement(616..1374)
                     /locus_tag="VVO74_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU5696022.1"
                     /translation="MEESKELNTVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1505..3484)
                     /gene="pknB"
                     /locus_tag="VVO74_002053"
     CDS             complement(1505..3484)
                     /gene="pknB"
                     /locus_tag="VVO74_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU5696023.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKTPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPIQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3481..4221)
                     /locus_tag="VVO74_002054"
     CDS             complement(3481..4221)
                     /locus_tag="VVO74_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU5696024.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(4236..5549)
                     /gene="rsmB"
                     /locus_tag="VVO74_002055"
     CDS             complement(4236..5549)
                     /gene="rsmB"
                     /locus_tag="VVO74_002055"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU5696025.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5542..6477)
                     /locus_tag="VVO74_002056"
     CDS             complement(5542..6477)
                     /locus_tag="VVO74_002056"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU5696026.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGCDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPKEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6490..8886)
                     /locus_tag="VVO74_002057"
     CDS             complement(6490..8886)
                     /locus_tag="VVO74_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU5696027.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYRHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(8952..9266)
                     /locus_tag="VVO74_002058"
     CDS             complement(8952..9266)
                     /locus_tag="VVO74_002058"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU5696028.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9291..9917)
                     /gene="gmk"
                     /locus_tag="VVO74_002059"
     CDS             complement(9291..9917)
                     /gene="gmk"
                     /locus_tag="VVO74_002059"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU5696029.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
BASE COUNT         2696 a         2400 c         2037 g         2917 t
ORIGIN      
        1 gaacaagagt tacttcaacc cattggctcc gacggattaa gttgctttcg tggataccaa
       61 aatcagccgc aatttcttca taagtgcggt attctcgcac atatagaaag cgttgttaat
      121 ttatttatct catttttcag aaaattcttt catttgtgta aagtctacga tactcgatgt
      181 gtttttatat aatgatacag tctgagaatc actgttccgc tagccattcc aatagagatt
      241 accaaagcca acatgacaac caaggtcgca cttgccagtg ctttattata gtcccctgtc
      301 acaaaaaagg cagttgttcg gtaggagaga taacctggaa ccagcggtgc caaaatggcc
      361 aagataaaga ccacagcagg tgtcttataa agaatactta aaatctggct gacacaagaa
      421 ccaataatgg ctgcaatgaa ggtagctaca atgacattgg tcggctcctt gagcaagaga
      481 tagattagcc agacagtcat gcccaaaatc cctccaggta agagcataga ccgttgcaca
      541 ttgagtacga ttaaaaaagt gataatggca agaaaacttg ctactgcttg taataaaaag
      601 gttgttagtg tcatattagt tcatcaatac caaggcgaca gaagttcctg cccctaaagc
      661 gagggtaatg agcagggatt caaacatctt actcatacca gagtttatgt ggttggtcat
      721 aatatcacgg accgcattgg tcaaggcaat acctggtaca aacggcatga ccgcaccagc
      781 tataatcaaa tctgccgttg aaggaaaacc tgtgtagcga gcccaaaact gggcaattat
      841 cccaaagaca aaggctccag caaaggctgt cacaaaggga attcggataa atttttccac
      901 atagagggaa aaggcaaaac caaataaggt cgccactcct gccccaagtg cgtcgtagat
      961 atttccgcta aacataactg aaaagaaagg agcgctaaag gtcgcagcca gagttacctg
     1021 caacttagta tagggaaggg gttgagcttg caaggccgtc aattgcttaa aggctgtttc
     1081 taaatcaatc tgccccccaa ccagctgacg agaaatctgg ttcacatcgc agactttttc
     1141 gatgttataa gaagaggagg tcacgcgctt catgcgcgaa atattggtat tttcaataga
     1201 gaaaaagata gcggcaggca tggcaaggac attgcaatcc acaatcccct gcgaatgcgc
     1261 gattcgaatc atggtatctt ctacacgatg gatttctgag ccacttttaa ggagaatagt
     1321 ccccgctagc ataatcacat caatgacggt atttaattct tttgattctt ccatgctttc
     1381 ctccttttat caactccctc tattctatca caaatccgga ctcaaaaaaa atctttgcca
     1441 tgaaatcatg acaaagattg attactcatt ttgattatcc atctgcttga ttatccatct
     1501 gcttttaagg agtagctgaa gttgttttag gtttgtagat tgaaatcttg actctagtct
     1561 tattgaggtc taccttttca cctgctctag gactttgttc aacaaccatg ccttctgcac
     1621 tacctgcagg cgctgtcgtc acttctacaa cttctatatt agcttcctta atcccaacaa
     1681 tttgaatcaa attgttctta gtaaactcca agctggaacc aatgtaactc ggcatggcaa
     1741 cacttgtaac ttttttagct actgtcaaga caatttgaat aggtttactc acatcatagg
     1801 tcgttccggc acctggactt tgtttcataa tcgttcctgg ttcgctttcg ctggactctt
     1861 cttcctctat cttaatcaaa ttctcaggaa ccttcttctg cttgagttct gagattactt
     1921 ctgtagagtt ccgtccaata tagttcccta attgaatcgt cgtagctttt ttagctactg
     1981 tcaaaacaat ttgagttgcc ttgctcaagt cataggtcgt accttctggt agactttgct
     2041 tcaggaccgt tccagcctca ctctcattgg actcttcttc ctcaatttta atcaaattat
     2101 ctggaacttt tttctctttt aattccgcaa tgacatcaga ggatttccga ccgacataat
     2161 tactaatttg gaaggattgc ttgcctgatg agacaaccaa attgattttc gttccttctt
     2221 ttcgaccagt tccagcgcca ggatctgtac ggataatccg cccttcttcc accttttcac
     2281 tagcctctgt cttctcctca ccaatctcaa aattggcttt tttgagcgtt gccttggcct
     2341 ctgcaactgt ctgacctgcc acatctggaa tggcaatggt tgcaggagtt ctggatagta
     2401 tccaaataag agaagctgcc accaatacaa ggctggccaa caaaatcagg taacgcatct
     2461 taaatctatg ttttttcggt gcttgtggtt ggtaagtttc ctctgtcaca gcctggcttg
     2521 gggttttgat tgatttgtgt tctgtctgcg cttgaacctt aggaatagat gtcaaggtac
     2581 tctgagaaac cttcggcaag gtcttggtat ctgccttgct cgtttcatca aagattaact
     2641 tactttcatt tctacgattg taggacaagc tactagacaa gtccacatac atctctgaaa
     2701 ccgagcggta gcgattggtc aactttttag cagttgcctt gataataaca ttttctaaag
     2761 cctgaggtac agatggattt tctgcaataa cggacggcag gggtttctgg aaatgctgga
     2821 gggcaatggt caccgcgcta tccccgtcat aagggatatg gcctgtcaac atctcataga
     2881 aaataatccc catagcatag atatcactct gcacagtcgc cttcgaacca cgcgcctgct
     2941 ctggggacaa gtaatgaact gagcccaaca tcgagttagt ctgggtcaga cttgtctctg
     3001 caaaggctac agcaatccca aagtctgtga cctttgcagt cccatctggt gtcaaaagga
     3061 tattttgagg tttcaagtcc ctgtgaacaa ttcctctggt atgggccaaa cgcatggcta
     3121 ggaggatttg tcccatgata cggactgctt cttcattaga aagaggataa tgttccttga
     3181 tatagcgttt gaggtctagt ccagcaacat actccattgc aagatactgt tgaccgtctt
     3241 cctcaccaat atctgttatc cgaacgatat gaggatggtc tagatctgcc atagctctcg
     3301 cttcacgctg aaaacgagct acagctatcg ggtccgtctg gtagttggtc ctcagaacct
     3361 tcactgccac ttcttcccca tctaagatta agtctttggc taggtagaca tccgccatac
     3421 ctcctcgacc aatctgtttg acaatccgat agcgtccggc aaaaatcttg ccgatttgga
     3481 tcattctgca tcctcctcgt tcatagaaac aagggcaacc gtaatgttgt ctaaacctcc
     3541 tgcattgtta gcaaaacgaa caagtgtctc cgttttatct gctaaaggaa tatcactggt
     3601 tacaatatca cgaatctcac tgcctgaaat catgttggtc aagccgtcac tattgagcaa
     3661 gagatagtca cctgactcaa ggataactgt cccaaaatca ggctgaattt catctttttg
     3721 cccaatagac tgggtgataa tatttttttg cggatgagct tctgcctctt ctggtgtcaa
     3781 ttgaccagcc ttgagcaatt cattaaccaa ggaatgatcg ctcgtcaact gatggtattc
     3841 ttctccacga atcaagccga tacgcgaatc accaatatga gcatagatag cctgattatc
     3901 aataatagca aggacttcca aagtagttcc catgcctctg taagcttcat cctgaccaag
     3961 ctggtgaatc ttttgatttt caatttctag gtaatgggcg aaccattcac gcacttcatt
     4021 gactgtatcg atctgggtat caacccaagc tacacccagg tctgtgaccg ccatttcact
     4081 agcgatattc cctgcacgat gacctcccat cccatcagct aaaataatca tggtacgtcc
     4141 agctctattg acatagtggt tgacatagtc ttggttattt gttcgtttct gaccaacatc
     4201 tgttaataat gaaatttcca tgtgtcagtt ccttcctaat ccgatatctt gcgaaattga
     4261 ctgatgaaga atccatcact tccatacaat tcaggtgtaa tgaggataca gccgtctttc
     4321 atgatatcct tacattcatg ttctagtttt acctgctcga actcgggatg actctctaaa
     4381 aaggccttaa cgacttgaaa attctcctct gagacgatag tgcaggtgct ataagttatt
     4441 ataccacctt tgcctagtat ttgacaaaca ctacctaata tttctaactg aatttcctgc
     4501 aaggacgcga aatctgccgt ttctttattg tatttgatat ctggttttcg gcgcaaaaga
     4561 ccgattcctg aacaaggagc atccaccaaa atcttatcaa aggaatcctg gtcaaaaaac
     4621 tcatgcacct ttctggcatc caatttttga gtttgaaccc gatcttcaac tcccagacgt
     4681 tgggcatttt cttgaattaa atccaacttg tggtcgtaca agtccagagc agtaacctga
     4741 cctgtcgtaa gataagaggc tatatgggct gttttcccac ctggagccgc acaggcatca
     4801 agcactcgct catcaccttg taaatcaagc gtcggagcaa ccagctgact ggactcgtct
     4861 tggatggtaa tggctccatc cgcaaacaaa ttatgccctg caaaatgccc ctgctcctta
     4921 accagaccag tggttgctaa aagggaatca ttcgcctcca acaaggcttg gatttcctct
     4981 tttcgactta ggtctgttac acgaatactg gctttgtttc gcactaacag gctttcaaag
     5041 atggcttttg ctctctcctc tccgtattct tccttgagtt tggcaactag ccaaactggg
     5101 agagaatagg caatggagtc acgcttgttt tttcgcttga tgctagcaat atctggccag
     5161 ccttcacgca agatacggcg aaggacagcg ttgaccaatt tttcactgcc ttttttacgg
     5221 agtttggcta attccactgc ttcattgacc acagcatgat ctggaatttt gtccaaatag
     5281 cggagttggt aggcactcat gagaagaagg acatagagcc agctgtctaa ctggtctctg
     5341 tcttcgataa agtgggatag gtaccattcc agagtcagtt tacgggctac cgttccatag
     5401 actagctcgg tcactaagcc cttgtctgct gcagagagct gactcccctt gaggtgttta
     5461 tttaaggcaa tatttgaata tgcttgattc acaaaaacat cctctagcac tgctagagct
     5521 aaacttctag ccgtttctac tttagtcacc aaatcgttct cctacagtca atgtacgtcc
     5581 aactccattg aggaaggaag caatgtccat cttaggctta ccagctggct gcacttgttt
     5641 gagggataga gccccttcag ccgttgcgac aatcaattct ttcttgccga tagagagaat
     5701 ctcacctgga tttccctgac cttctactgg tagggcttca taaatcttaa agcggtcgcc
     5761 cttaaggaaa gtatgggcaa caggccaggg gttcattcca cgaatttggt taaagagttg
     5821 acgattggtt ttgttccagt ccagtttttc ttcctttggc tttatatttg gagagaaggt
     5881 aacctgactc gtatcctgcg gttcaggttt gatatcacca gcaatatagg caggcagagt
     5941 gtccaaaagc aaatcacaac caactagcgc caatttttca aacaaggtgc caacattgtc
     6001 ctcatctgtg atcggaatgc tgcgacgaga aatcatatct cctgcatcca tttccttaac
     6061 catttccatg atggtcacac cagcttcctc atccccttga atcaaggcat aatggatagg
     6121 cgcaccacca cggtgtctag gaaggaggga ggcatgaacg ttgacagcaa agtccatgct
     6181 atcaaggagt ttgcttggga gaaactgccc aaaagcagca gtcacaattc catctgctcc
     6241 tagcttcata agatcttcca tctctggact tccagataat ttttcaggtt ggtagataga
     6301 tagtcctgct tccttggcag cctgcttgac tggggtttct tggataactt ttttacgacc
     6361 aacagcacgg tctggctggg tcacaacggc tagaatttcg taacggtcat ctgtcaaaag
     6421 tccttttaag actgttgctg aaaagtcggg ggtccccata aagattagtt ttgtcatatc
     6481 ttctccttct tataaaaatt gctgcggctc atggtcaatg ctgagacgga gctcactatt
     6541 ttcccgttct tgagtcaagg ccaagacctg gttgagggtc ggccccagct catcttctaa
     6601 acggtattta attaaaatct ggtaatgata gaggttgtgg gtacgggcaa tcggttttgg
     6661 cgttggcccc agaatgggac tggtctctga caagcctgac cgcaaaatgt tcatgacttc
     6721 ataggcacgt ttgaaaacct cttcttcttt cttgtgagaa agggtaatac caatcgtgaa
     6781 atagtaaggt ggatagccga gttgtcgtct gattcccatt tcataggcat aaaagccttc
     6841 gtaatcttga tccttggcaa atcgaatagc atagtgctgc gaattgtagg actgtatcaa
     6901 gacttgacct gctttttcag cccgacctgc tcgacctgcc acctgagtca agagctggaa
     6961 ggttctctca gaagaacgga aatcaggcag attcaaggcc gtatccgcat ttagaactcc
     7021 gactagggta acattgggaa aatccaaacc ctttgcaatc atctgagtac caagtaaaat
     7081 atccgcttcc cctcgcccaa actggtcaag caaggcttgg tgactgcctt tctttcgagt
     7141 cgtatccaca tccatcctca aaatgcgagc ttggggaaag agttctgcta gctcatcata
     7201 agccttctga gttcccgtcc catagtaacg aatactgcgg ctcttacagt taggacagac
     7261 ctgaggaata tccttcgaga aaccacaata atggcagttc atagtcttgg tatccatatg
     7321 caaggtcaga gaaatatcgc agttgggaca agtatccacc gtcccacact cccgacacat
     7381 gacaaagcta gaataaccac ggcgattgag catgagaacc acctgctctt ttttaaccag
     7441 acggtcttgg atagcctcta gcaaaggagg cgtaaagttt gacgtctcat tttgtccgat
     7501 atagtctcga aagtcaatca cttgaacctc agggattgta gccaaaggat tggcacgttg
     7561 ggttagacgt aagtgtcgat agacgccttt gccagcacgt gcccggctct ctaagctcgg
     7621 cgttgcagat ccaagtacca gagttgcttg attatactga gcccgtaaaa tagctacctc
     7681 tctggcatgg taacggggat tgctgtcctg cttataagcc gcttcatgct cttcatcaat
     7741 aatcatgaca cccagatttt tcagaggagc aaagatagca gatctggcac caacaacaac
     7801 ttgggcatcg ccacgctcca ccttgcgcca ttcatcatac ttttcgccat tggataatcc
     7861 tgagtgaaga atggctacct tgtccccaaa acgtgctata aaacgctcgg tcatctgagg
     7921 agtcaaggaa atctcaggta ccagcaaaat agctgtctta cccttatcca gggcaccttg
     7981 gataatctgc aagtaaacct cggtcttccc acttcctgta atcccttgaa gtagaaaggg
     8041 aggttgagaa ctgccaatag aactcacaac cgcatcacgc gcctgtcttt gttctggatt
     8101 taactccaaa ggtctacttg cttcaattcc ttcaaaataa gcagccgagc gttgaacttc
     8161 cttttggact atggtaacag caccttgatc cacaaagaag ttgacttgct ctcgcgagta
     8221 ggactctaac aagctagcca aggaagcgct ctctggatga gacagcagat aatctctcag
     8281 ttccaacttt ttcttggcac gtgtagaaat ctcaacacct tctaattggg catggtcaac
     8341 ctcataccaa gactgggtct tgaccttctt ttgatcgact gcctgatatt ccagaccaag
     8401 caggcctttt ctagtcaaac gcatcatttc agcttgcttg gcaaggtcta gtgaagaaaa
     8461 ggctagcgaa tcttctgaac caaacaggcg tactcgttct tcctgactca agccttccag
     8521 aggatagaga atcttgtcat agctagaatt cagaaaccct ggaagcatgg ccttgaggat
     8581 agagattttg taggagaaga cagatttgcg taactcctca gccagccaga gttgttctgg
     8641 cgtgagaaca ggagaaaaat ccagcacctc tgcaatatct tttaaatctt gctccatctc
     8701 ttctccatct gattgggact tcaaaccaag aacaatccct tgaatcaggc gattcccctt
     8761 accaaaaggc acatgaaccc gcatcccaac ttccagcatt ccctcaaatt cctccggaat
     8821 cctgtaacta tagggctggt ccgtctgcat caagggcaca tctacgataa tcttagctag
     8881 ggccatcttc tcacctcctc cttgtcagta cattcttgca atagaaaaaa taagattgag
     8941 tccccccaac cttaaatttt ttcaccatct tctttttctt tagcaatttg ctctttgatt
     9001 ttcttttctt cttcttcttt gcggcgtttt tcttcttcga tacggcgacg cactgcttca
     9061 cgttttcctt ctggatctgg gtgaattgta acgtttcctg attcgatttc ttctaaagcg
     9121 cgaagagttg atttttcaga cttgaaacct tgagttgctg gggcacctgc ttccaattcg
     9181 tgggcacgtt ttgcttccaa gattacgagt gaatattttg aaggaacctt gtcgagcaag
     9241 gtatcaatag agggttttaa catcatttgc ttgtacctat tttctaaatt ttatcgggta
     9301 gttggagatt ttggtaacat ctcctgatag tgaccaatga cacgatccac acagaagtgt
     9361 tctgcttcaa tcacacattt gacacgttca gcagctaggg gcacctgatc gttgacaatc
     9421 gcataatcat actcacgcat gagggcaatt tcttccttgg ccttttcgat tcgttgggca
     9481 atcacttctg cactatctgt tccacgacct accaagcgat cttgcaattc atccaaatct
     9541 ggtggtgtca ggaagataaa gacagcatct ggaacctttt tcttgacctg aagagcaccc
     9601 tgaacttcaa tttcaaggaa aacatcgatt cccttgtcca aggtttcatt gacataggtc
     9661 agaggagttc catagtagtt gccgacatat tctgcgtatt ccaacatctg tccttgacga
     9721 atcagctctt caaattcttc acgagtacgg aagaaatagt caacaccgtc cacttctcca
     9781 ggacgttgtg cgcgtgtcgt catcgataca gaatattgaa attggttttc agaactctca
     9841 aaaatctctc ttctaaccgt tccttttcca acccctgaag gaccagaaaa aacgattagt
     9901 aagcctcggt ctgccattgt gtctcctttt agtcaatctg tgaaataaca tttctctaga
     9961 ataatggcaa aaagccagat tatcctttac agtctttcta tctagtgtaa caaaaaagca
    10021 gtaatttttc aactgctctt tcttatttat
//
LOCUS       DAVHKZ010000061         9701 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000061 DAVHKZ010000000
VERSION     DAVHKZ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9701
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.061"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            225..4922
                     /locus_tag="VVO74_002060"
                     /pseudo
     CDS             225..4922
                     /locus_tag="VVO74_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856114.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
     gene            6554..6704
                     /locus_tag="VVO74_002061"
                     /pseudo
     CDS             6554..6704
                     /locus_tag="VVO74_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843696.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            7283..7759
                     /locus_tag="VVO74_002062"
     CDS             7283..7759
                     /locus_tag="VVO74_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU5696030.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAETTA"
     gene            7797..8102
                     /locus_tag="VVO74_002063"
     CDS             7797..8102
                     /locus_tag="VVO74_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU5696031.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            8150..9625
                     /locus_tag="VVO74_002064"
     CDS             8150..9625
                     /locus_tag="VVO74_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU5696032.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT         3596 a         1451 c         1870 g         2784 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttttgactt
       61 aaattttttt aaatgatata ctgtttttat agagagataa caattatata taaatgtact
      121 actctatttc ctagataata cttagtaaaa ctttttataa caaaggctag caaagttaaa
      181 gtttattatc tattggaagt taaataaata tgtaaggaat taaaatgaaa aaaagcacag
      241 tattgtcatt aactacagct gcagttattt tagcagccta tgcccctaat gaggtagtct
      301 tagcagacac atctagctct gaagatgctt taagcatctc tgataaagaa aaagtagtag
      361 tagataagga aacagaaaat aaagagaaac ataaagatat tcataatgct atagaaactt
      421 caaaggatac tgaagaaaag aaaacaacaa ttattgagga aaaagaagtt gttagtaaaa
      481 atcctgtaat agacactaaa actagcaatg aagaagcaaa aatcaaagaa gaaaattcca
      541 atcaatccca aggagatcat acggactcat ttgtgaataa aaacacagaa aatcccaaaa
      601 aagaagataa agttgtctat attgctgaat ttaaagataa agaatctgga gaaaaagcaa
      661 tcaagggact atcaaatctt aagaatacaa aagttttata tacttatgat agaattttta
      721 acggtagtgc catagaaaca actccagata acttggacaa aattaaacaa atagaaggta
      781 tttcatcgat tgaaagggca caaaaagtcc aacccatgat gaatcatgcc agaaaggaaa
      841 ttggagttga ggaagctatt gattacctaa agtctatcaa tgctccgttt gggaaaaatt
      901 ttgatggtag aggtatggtc atttcaaata tcgatactgg aacagattat agacataagg
      961 ctatgagaat cgatgatgat gccaaagcct caatgagatt taaaaaagaa gacttaaaag
     1021 gaactgataa aaattattgg ttgagtgata aaatccctca tgcgttcaat tattataatg
     1081 gtggcaaaat cactgtagaa aaatatgatg atggaaggga ttattttgac ccacatggga
     1141 tgcatattgc agggattctt gctggaaatg atactgaaca agatatcaaa aactttaacg
     1201 gcatagatgg aattgcacct aatgcacaaa ttttctctta caaaatgtat tctgacgcag
     1261 gatctgggtt tgcgggtgat gaaacaatgt ttcatgctat tgaagattct atcaaacaca
     1321 acgttgatgt tgtttcggta tcatctggtt ttacaggaac aggtcttgta ggtgagaaat
     1381 attggcaagc tattcgggca ttaagaaaag caggcattcc aatggttgtc gctacgggta
     1441 actatgcgac ttctgcttca agttcttcat gggatttagt agcaaataat catctgaaaa
     1501 tgaccgacac tggaaatgta acacgaactg cagcacatga ggatgcgata gcggtcgctt
     1561 ctgctaaaaa tcaaacagtt gagtttgata aagttaacat aggtggagaa agttttaaat
     1621 acagaaatat aggggccttt ttcgataaga ataaaatcac aacaaatgaa gatggaacaa
     1681 aagctcctag taaattaaaa tttgtatata taggcaaggg gcaagaccaa gatttgatag
     1741 gtttggatct taggggcaaa attgcagtaa tggatagaat ttatacaaag gatttaaaaa
     1801 atgcttttaa aaaagctatg gataagggtg cacgcgccat tatggttgta aatactgtaa
     1861 attactacaa tagagataat tggacagagc ttccagctat gggatatgaa gcggatgaag
     1921 gtactaaaag tcaagtgttt tcaatttcag gagatgatgg tgtaaagcta tggaacatga
     1981 ttaatcctga taaaaaaact gaagtcaaaa gaaataataa agaagatttt aaagataaat
     2041 tggagcaata ctatccaatt gatatggaaa gttttaattc caacaaaccg aatgtaggtg
     2101 acgaaaaaga gattgacttt aagtttgcac ctgacacaga caaagaactc tataaagaag
     2161 atatcatcgt tccagcagga tccacatctt gggggccaag aatagattta cttttaaaac
     2221 ccgatgtttc agcacctggt aaaaatatta aatctacgct taatgttatt aatggcaaat
     2281 caacttatgg ctatatgtca ggaactagta tggcgactcc aatcgtggca gcttctactg
     2341 ttttgattag accgaaatta aaggaaatgc ttgaaagacc tgtattgaaa aatcttaagg
     2401 gagatgacaa aatagatctt acaagtctta caaaaattgc cctacaaaat actgctcgac
     2461 ctatgatgga tgcaacttct tggaaagaaa aaagtcaata ctttgcatca cctagacaac
     2521 agggagcagg cctaattaat gtggccaatg ctttgagaaa tgaagttgta gcaactttca
     2581 aaaacactga ttctaaaggt ttggtaaact catatggttc catttctctt aaagaaataa
     2641 aaggtgataa aaaatacttt acaatcaagc ttcacaatac atcaaacaga cctttgactt
     2701 ttaaagtttc agcatcagcg ataactacag attctctaac tgacagatta aaacttgatg
     2761 aaacatataa agatgaaaaa tctccagatg gtaagcaaat tgttccagaa attcacccag
     2821 aaaaagtcaa aggagcaaat atcacatttg agcatgatac tttcactata ggcgcaaatt
     2881 ctagctttga tttgaatgcg gttataaatg ttggagaggc caaaaacaaa aataaatttg
     2941 tagaatcatt tattcatttt gagtcagtgg aagaaatgga agctctaaac tccaacggga
     3001 agaaaataaa cttccaacct tctttgtcga tgcctctaat gggatttgct gggaattgga
     3061 accacgaacc aatccttgat aaatgggctt gggaagaagg gtcaagatca aaaacactgg
     3121 gaggttatga tgatgatggt aaaccgaaaa ttccaggaac cttaaataag ggaattggtg
     3181 gagaacatgg tatagataaa tttaatccag caggagttat acaaaataga aaagataaaa
     3241 atacaacatc cctggatcaa aatccagaat tatttgcttt caataaccaa gggatcaacg
     3301 ctccatcatc aagtggttct aagattgcta acatttatcc tttagattca aatggaaatc
     3361 ctcaagatgc tcaacttgaa agaggattaa caccttctcc acttgtatta agaagtgcag
     3421 aagaaggatt gatttcaata gtaaatacaa ataaagaggg agaaaatcaa agagacttaa
     3481 aagtcatttc gagagaacac tttattagag gaattttaaa ttctaaaagc aatgatgcaa
     3541 agggaatcaa atcatctaaa ctaaaagttt ggggtgactt gaagtgggat ggactcatct
     3601 ataatcctag aggtagagaa gaaaatgcac cagaaagtaa ggataatcaa gatcctgcta
     3661 ctaagataag aggtcaattt gaaccgattg cggaaggtca atatttctat aaatttaaat
     3721 atagattaac taaagattac ccatggcagg tttcctatat tcctgtaaaa attgataaca
     3781 ccgcccctaa gattgtttcg gttgattttt caaatcctga aaaaattaag ttgattacaa
     3841 aggatactta tcataaggta aaagatcagt ataagaatga aacgctattt gcgagagatc
     3901 aaaaagaaca tcctgaaaaa tttgacgaga ttgcgaacga agtttggtat gctggcgccg
     3961 ctcttgttaa tgaagatgga gaggttgaaa aaaatcttga agtaacttac gcaggtgagg
     4021 gtcaaggaag aaatagaaaa cttgacaaag acggaaatac catttatgaa attaaaggtg
     4081 caggagattt aagaggaaaa atcattgaag tcattgcatt agatggttct agcaatttca
     4141 caaagattca tagaattaaa tttgctgatc aggctgatga aaaggggatg atttcttatt
     4201 acctagtaga tcctgacaaa gatgcttcta aatatgaaaa acttggtgaa atttctgaag
     4261 ataaactcaa aaatgcaaag agcccagagg aaaataccaa taataatcaa gctaaggatg
     4321 aagattcaaa accagatgaa aaagttcagt tgagggagaa gctagccttg aaataaataa
     4381 aactatttca acaattagag agtttgaaaa taaagaccta aagaaactca ttaaaaagaa
     4441 atttagagaa gttgatgatt ttacaagtga aactggtaag agaatagagg aatacgatta
     4501 taaatacgat gataagagaa atattattgc ttatgacgat ggtagtgcct tacaatatga
     4561 aactgaaaaa tttgacgaaa taaaatcaaa aatttatggt gttctaagcc catctaaaga
     4621 tggacacttt gaaattcttg gaaagataag caatgtttct aaaaatgcca aggtatatta
     4681 tggaaatagc tataaatcga tagaaatcaa agcgactaag tatgattcac attcaaaaac
     4741 gatgatattt gatttatacg ctaatattaa tgatattgta gatggattag cttttgctgg
     4801 agatatgaga ttatttgtta aagatgacaa tcaaataaaa gctgaaacta agattagaat
     4861 gcctgaaaaa aataaggaaa ctaaagcaga atatccctat gtatcaagtt atgggaatgt
     4921 aatcgaatta ggagaaggag atctttcaaa gaacaaacca gacaatttaa ctaaaatgga
     4981 atctggtaaa atctattctg attcagaaaa acaacaatat ctgttaaagg ataacatcat
     5041 tctaagaaaa ggctatgcac taaaagtgac tacctataat cctggaaaaa cggatatgtt
     5101 agaaggaaat ggagtctata gcaaggaaga tatagcaaaa atacaaaagg ccaatcctaa
     5161 tctaagagtc ctttcagaaa caacaattta tgctgatagt agaaatgttg aagatggaag
     5221 aagtacccaa gctgtattaa tgtcggcttt ggacggcttt aacattataa ggtatcaagt
     5281 gtttacattt aaaatgaacg ataaagggga agctatcgat aaagacggaa atcttgtgac
     5341 agattcttct aaacttgtat tatttggtaa ggatgataaa gaatacactg gagaggataa
     5401 gtccaatgta gaagctataa aagaagatgg ctccatgtta tttattgata ccaaaccagt
     5461 aaacctttca atggataaga actactttaa tccatctaaa tctaataaaa tttatgtacg
     5521 aaatccagaa ttttatttaa gaggtaagat ttctgataag ggtggtttta actgggaatt
     5581 gagagttaat gaatcggttg tagataatta tttaatctac ggagatttac acattgataa
     5641 cactagagat tttaatatta agctgaatgt taaagacggt gacatcatgg actggggaat
     5701 gaaagactat aaagcaaacg gatttccaga taaggtaaca gatatggatg gaaatgttta
     5761 tcttcaaact ggctatagcg atttgaatgc taaagcagtt ggagtccact atcagttttt
     5821 atatgataat gttaaacctg aagtaaacat tgatcctaag ggaaatacta gtatcgaata
     5881 tgctgatgga aaatctgtag tctttaacat caatgataaa agaaataatg gattcgatgg
     5941 tgagattcaa gaacaacata tttatgtaaa tggaaaagaa tatacatcat ttgatgatat
     6001 taaacaaata acagacaaga cactaaacat taagattgtt gtaaaagatt ttgcaagaaa
     6061 tacaaccgta aaagaattca ttttaaataa agatacggga gaggtaagtg aattaaaacc
     6121 tcatagggta actgtgacca ttcaaaatgg aaaagaaatg agttcaacga tagtgtcgga
     6181 agaagatttt attttacctg tttataaggg tgaattagaa aaaggatacc aatttgatgg
     6241 ttgggaaatt tctggtttcg aaggtaaaaa agacgctggc tatgttatta atctatcaaa
     6301 agataccttt ataaaacctg tattcaagaa aatagaggag aaaaaggagg aagagaataa
     6361 acctactttt gatgtatcga aaaagaaaga taacccacaa gtaaatcata gtcaattaaa
     6421 tgaaagtcac agaaaagagg atttacaaag agaagatcat tcacaaaaat ctgattcaac
     6481 taaggatgtt acagctacag ttcttgataa aaacaatatc agtagtaaat caactactaa
     6541 caatcctaat aagttgccaa aaactggaac agcaagcgga gcccagacac tattagctgc
     6601 cggaataatg tttatagtag gaatttttct tggattgaag aaaaaaaatc aagattaaga
     6661 caaaagctat agaaaaaaat ggtttatgta ctgagattag atagtgaggt gatgacatag
     6721 ttttgtgaaa acagccattt ataactcaat tatttagttt acttcactat tgatactatt
     6781 tggagttatt aatggactta gtttagataa ctaatgaatt gattgaaagg gttagtattg
     6841 acaatattgg tcatattgat tagaaaatag agtctatcaa aatttaaagg ctaatagagg
     6901 tgatgagaca atttcaagga attaagtagc gtttggttgc ttaattcctt tttatttgga
     6961 aggaagtttt tcgtaaccgc ccaataacga agtctattgg acggttacga tatgatcact
     7021 gacttcgtca gtcttatcta caacctcaaa actgtgtttt gagcaacctg cggctagctt
     7081 cctagtttac tctttgattt tcattgagta ttagaacaga aaaaatgctt ggagtatttg
     7141 tttgtgtgtt tatttttata taacaaacta taaacaaaaa aaaatataaa aaaagagaca
     7201 aaaaagaaca gaaagtaatt gacaacggtt tcatatagtg ttatacttat ggcataaagt
     7261 taatggaaag aagggaaaac ttatggtatt agattatttc tttgacaaaa accttgtgtt
     7321 ttgcttagaa gcggataatc aagaacaact ctttgatcag gttgcaactt tattggaaga
     7381 acgagaaatt gtcactccaa cttatcgtga agccttgatc acgcgtgaaa agtcatttcc
     7441 aactggttta gatatggaat ttctaggaaa ggacttgcca aatgtagcga ttcctcatac
     7501 agatattgtt cataatctag ctgagaaagt ggtggttgtt cgattagaaa aaccagtaac
     7561 ttttcacaat atgatagctc ctgataagga agtagaagta tccttgctct tctttatcat
     7621 caataactca agttcaagtc aaacaaatat tctggctcag ttgatggact ttttcacagg
     7681 aaatggacat cttgaagacc tatcaaaaat ttccgaacca gaaaaacttt atgcttacat
     7741 tgctgaaaca accgcttaat cttgtctatt aaaaaataaa atcggaggaa atctaaatga
     7801 ttaaaattct tgctgcctgc ggtgcaggtg ttaactcaag tcaccaaatt aaaagtgctc
     7861 tagaagaaga actttcaaac cgtggttatg atgttcactg tgatgcagtc atggtgaaag
     7921 atgtaaacga agaccttatg aaaggttacg atatctttac accaatcgct gcaacagacc
     7981 ttggttttga accaggtatc ccagttatcg aagctggacc aatcttattc cgtatcccag
     8041 caatgagcgc tccagtattt gacaatattg aagcagctat taaagaacat ggattaagct
     8101 aattctaatt tgttaacatt catataacat aaaaaaggga ggaactgtta tggatgcaat
     8161 ctttgaccta atcggaaagg ttttcaatcc catcttagaa atgggtggac ctgtcatcat
     8221 gttgatcatt ttgacagtat tggctttact ttttggagtg aaattctcca aagcgcttga
     8281 aggtggtatc aaacttgcca tcgctcttac aggtatcggt gctatcatcg gtatgctaaa
     8341 tggtgctttc tcagcatcac ttgcaaaatt cgttgaaaac actggtatcc aattgagtat
     8401 tacagacgtt ggttgggcac cactcgcaac aatcacttgg ggttctgctt ggacactata
     8461 cttcttgctc atcatgttga ttgtcaacgt agtgatgctt gctatgaaga aaaccgatac
     8521 acttgatgtc gatatctttg atatctggca cttgtctatc acaggtctct tgattaaatg
     8581 gtatgctgat aacaatggtg tgagtcaagg ggtttcactc tttattgcta cagcagctat
     8641 cgtccttgtc ggtgtgttga aaattatcaa ctctgacttg atgaaaccta catttgatga
     8701 ccttcttaac gccccaagtt catcaccaat gacatcaact cacatgaact acatgatgaa
     8761 cccagttatc atggttttgg ataagatttt tgaaaaattc ttcccaggcc ttgataaata
     8821 tgactttgat gctgctaaat tgaacaagaa aatcggtttc tggggatcta aattcttcat
     8881 cggtttcatc cttggtatcg ttatcggtat tatgggaact ccacatccaa ttgcaggtgt
     8941 tgcagatgca gataaatggc gtcttgttat caaaggatgg ttgtctcttg gtttgactgc
     9001 cggtgtatct ttggaactct tctcacttat cggttcatgg ttcatcgcag ccgtagaacc
     9061 actatcacaa ggtattacaa acgttgctac taaacgtctt caaggacgta aattcaatat
     9121 cggtcttgac tggccattca tcgctggtcg tgctgaaatc tgggcttgtg ccaacgtact
     9181 tgcaccaatc atgttgattg aagcagtgct tctttcaaaa gttggaaatg gtatcttgcc
     9241 acttgcaggt atcatcgcta tgggtgttac tccagctctc ttggttgtaa ctcgtggtaa
     9301 attgctccgt atgattatct tcggaacact cttgttgcca ctcttccttc tttcaggtac
     9361 acttattgca ccatttgcaa cagaacttgc taaaggtgta ggtgccttcc cagaaggtgt
     9421 gagccaaact caattgatta ctcactctac tcttgaagga ccaatcgaaa aacttcttgg
     9481 ttggacaatt ggtaacacta caactggtga tatcaaagca atccttggtg cagtagtctt
     9541 ccttgtattc tatatcggta tctttgcttg gtacagaaaa caaatgatca aacgtaacga
     9601 agagtacgca gcaaaagcaa aataatgcgc tcctataaaa tataaactta atgaaaatca
     9661 aagagcaaac taggaagcta gccgcaggtt gctcaaaaca c
//
LOCUS       DAVHKZ010000062         8885 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000062 DAVHKZ010000000
VERSION     DAVHKZ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8885
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.062"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            168..854
                     /locus_tag="VVO74_002065"
     CDS             168..854
                     /locus_tag="VVO74_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU5696033.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            855..1787
                     /locus_tag="VVO74_002066"
     CDS             855..1787
                     /locus_tag="VVO74_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU5696034.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            1798..2727
                     /locus_tag="VVO74_002067"
     CDS             1798..2727
                     /locus_tag="VVO74_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU5696035.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            2741..4180
                     /locus_tag="VVO74_002068"
     CDS             2741..4180
                     /locus_tag="VVO74_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696036.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            4249..5826
                     /locus_tag="VVO74_002069"
     CDS             4249..5826
                     /locus_tag="VVO74_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU5696037.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPKINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            5886..7347
                     /locus_tag="VVO74_002070"
                     /pseudo
     CDS             5886..7347
                     /locus_tag="VVO74_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
     gene            7369..7824
                     /locus_tag="VVO74_002071"
     CDS             7369..7824
                     /locus_tag="VVO74_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HEU5696038.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            7911..8317
                     /gene="cdd"
                     /locus_tag="VVO74_002072"
                     /pseudo
     CDS             7911..8317
                     /gene="cdd"
                     /locus_tag="VVO74_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            8330..8779
                     /locus_tag="VVO74_002073"
     CDS             8330..8779
                     /locus_tag="VVO74_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU5696039.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDIPKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEEIILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHKTGLLVEEPLNIKKVVFKVKI"
BASE COUNT         3095 a         1151 c         1663 g         2976 t
ORIGIN      
        1 gtgtattgaa tctataacag tacgccttaa atgctaaaat atttctataa attaatttaa
       61 ctttcctgat agggctgttc atatcttatt tcaattcact atataaataa aattgtagta
      121 gatgttattg aattagtaaa aaaaataaaa aaacggaggt tttctgaatg gaaactaaaa
      181 aaattaaaaa tttaaaaggt caaataattg tttcctgcca agcgttagaa ggagagccac
      241 tttatactcc aaatggagga gtgatgccgt tattagcaaa agccgccttt caagcaggcg
      301 ctaaaggtat tcgtgctaat tctgtccgcg atatttcaga aataaaagaa gaagttgact
      361 taccaattat aggtatcata aaaagagatt acgatggctt tgaacctttt atttcagcaa
      421 ctatgaaaga gattgatgaa ttagttagtg aaggagtaga cattttagct ttggattgta
      481 ctaatcgttc aagaccaggt tatgataata ttactgactt tattcatgat attaaagtca
      541 agtatccaaa ccaattatta atggctgata tttctacttt tgaagaaggg aaagtagctg
      601 ctgaatcggg agtagatttt gtgggtacga cattatctgg ttatacacca tatagcccta
      661 aaaaagataa tcctgatttt gagttagttg aaagattggt aaaagagctt gacgtaccag
      721 ttattgctga aggaagaata agtactccgg aacaagctag aaaaatgtta gatttaggtg
      781 cttacgcagt ggttgttgga ggagctatca ctcgtccttt ggaaatagcg aagaagttta
      841 ttgaggtagt ttagatgaat caagaaatat taaaaaagag taagattcaa ttgacagttg
      901 aacatattca aaaatattgg attttatatt taatgatgat tccagcaact gttctactaa
      961 ttttatttac gtatggacca atgtacggca ttattatggc ctttcaagac tttactgtct
     1021 tcaagggata tactggaagt ccatttgtcg gtttaaaaca ttttcaaaga ttgttctcag
     1081 atcctttgtt ttatagattg ttcaagaata cgttcatggt aggggtttta gactttttat
     1141 tctctttccc agctccgctt atttttgcac tcatattaaa cgaagtcaga aaagtaagat
     1201 ttaagagtgt agttcaatct attagttatc ttcctcattt tattccccta gtggttatgg
     1261 ttggtattat ttttgaacta tttggttcat atggtattat taacagttta ctttcatcac
     1321 ttggaatgga gccaataagt ttctttacaa aatctgaatg gttcttgcct ctctacattg
     1381 gttcaggagt atggaaaaca ataggttggg gttctatcat ttatatggga gcattaacca
     1441 atatagattc aactttatat gaagcagcag atatggacgg ggctaataga tggcacaaaa
     1501 tgtggcatgt aactctacca agtttaagac ctacagtagt tactttgttt atactaaatg
     1561 ctggtggtat catgcaagta ggatttgaaa aggtattctt gatgtctagt cctgcaacat
     1621 atgaagtatc tgatgtatta tctacttatg tttatagaca aggtatttta aattctgatt
     1681 tcagttactc agctgcagta ggattattta ataacatagt agctttgtta tttgttttat
     1741 tagctaataa gattgctaaa aaacttggcg aagaaggaat tgtataaggg gggtaaaatg
     1801 attttttcaa aaaatacaaa aaagagtaat agagacaaag aaaccttcgt tgattatctc
     1861 tttatattca ttttaataat aataacctta cttatgttgt atccattatg gtgggtagtg
     1921 atgacgtcac tttcagaacc agtttggcta tctaaaaacg ttgttaaatt atttccctta
     1981 aaaatagata ttactgcata taagtttatt tttggggatt ctaaactatg gcaagcatat
     2041 ggtaatagtg tattgtatgc tgcactatct acaattgtta gtgttgcggt atgtagtatg
     2101 tatgcctatc cacttacaat tcctgaaatt aggggtaaaa aattctggaa tactcttatt
     2161 ttgattccaa tgttctttag tggaggaatg atcccgcttt atatacaagt tgcaaacctc
     2221 ggtttattga atactgcttg ggctcttgtt ttacctggtg ctgtttctac atattatata
     2281 attttgttta gaacacagtt taaatcaatc ccaatggagc ttcgtgagtc tgctagaatt
     2341 gatggggcaa gtgaatttag aattttttgg aatttagtat taccattatc aaaagttatt
     2401 ttcatgatta tagcacttta ttgcatagtt ggttcatgga atagttttac tcctccatta
     2461 ctttatttga atgacgacac taagatgcct ttatctattt atttgagaaa tttagttgtt
     2521 acaaatacaa ctgatactgc tgaattatca ctttctgcag gtaatacata ttaccaacaa
     2581 attgctgctc aaggtggagg tattggtatg cgtattgcta ttaagatggg tactattgtt
     2641 gttagtgtta ttccaattat gatgatttat ccatttattc agaaacattt tgttaaggga
     2701 atcctgctag gttctgtgaa aggttaataa ggtaattatt ttgcaaaatt taaaaaaata
     2761 tcttttatta gatagcggtt tagtagttgg gtatacatta gaaaatgctc aattaaaatt
     2821 aaataagcta aaaaaagata ctgaaaacaa tccactattt ggtgaagagt attttgccga
     2881 aaatcctaaa ttatgggaag ttcgttttga taattcatat ccaaacgtta tctatgataa
     2941 agaattgaaa ttatatagat gttggtatca aacatttgtt agtgatgaag caagcgaaga
     3001 gactccttta gcagaacgtg gagagaagga atacattgtc aagtcatcta gaatgacagc
     3061 actttgctat gctgaaagta aagatggagt aaaatgggaa aaaccaaatc tcaatctagt
     3121 aaaatttaaa ggttcaaaag ataataatat tgttctgatg catgcacacg gtgcaggtat
     3181 catgctagat gaacaggagt tggatcctaa gaaacgatat aaattagttt caaaattaga
     3241 attttctccg aatcttcatt acatggttgt tgttttttca gaagacggta ttcattttga
     3301 cgaacctatt ccatggaaaa aatggaatcc tgcagcagat agtcataatt ttccatttag
     3361 agatccaaaa actggtaaat acgctgttat tacaagaacc tgggcaaata acgtacgtct
     3421 aagtgcaatt actttcagtg atgattttat taattggtca gaacctaaag aaatccttag
     3481 gggagatgga tttgaagatc aaatttattc tatgccagta atttcatacg cggatatcta
     3541 tttaggtttt gcttcaatgt accacgaagg cgacacttta aatgaaaact atgataaagt
     3601 agacttagaa ttgaaattct ctgctaattt ggaacaatgg gatagtgtat gtaagggcga
     3661 ctatctcatt gaaaggggag gtggagtata cccgcagaat gctgattttg atgctagttg
     3721 tattttcacg gctgctccaa taattgaaga tgataagatt tggttctact atatgggtgg
     3781 aaatggtaat cacactggct tccgagaaag ttcattagct agaggatata ttaagaaaga
     3841 ccaatttgct tattatacta ataagagaga aggaattcca gctaaaatat ctacagttag
     3901 cttccaaact tacgatgatg aaatttatat cttagctgat attcctgaaa atggttatat
     3961 taaagttgcg gtaggtacta aatacggtaa tgcttattca gattttggtc aggaagatat
     4021 ctctcttgtt caagtttccg atggtaagta taagttggaa tttaataaaa aatctatctt
     4081 agatttaggt aattctccag ttgcgttcaa atttgaaatc gagaatgcaa aattgtatgg
     4141 tattgaaggt agtattcagc aacactatct caaatattaa ccagaataat tcgttaacaa
     4201 ataatctcta tattagtgga gatagatata taaaatggag gtcttattat ggtaaagctt
     4261 aataaggtat taaaagggag tgttgcattc ctgagtgcaa gtttattgct agcagcttgt
     4321 ggcaataacg ctaattcaaa gcccgctgaa aaaacagctg atggtaaaac gaaaatttcg
     4381 tttctatcta catggcaaat taatgatgtt cgtccgccta aagatgaaac acttgttggt
     4441 caatggttag aagaacagct aggtattgat attgatcttg taactattcc tggcgaggga
     4501 gtaagttcta aagtaaattc tcttattact agtaaccagt taccgactgt tttgttgaca
     4561 acaggagata agagtgatat cgctggtatc aacaaacttg gtaaacaggg tgcattctta
     4621 gatttgtcac aacacatgga caaactacca aactataaga agtaccttga aaaaaataat
     4681 gcattagctc aaatagaaga tgatgaaaaa catatttatg ctttcacaaa attctttact
     4741 gatgagaata tcatgtatac tacaccaatt ctgagaaaag acttacttgt tggttcagaa
     4801 tttgaagatc tttcaaaaat taaaactgtt gatgactata caaaagtttt gaaatatttg
     4861 actgaaaaac aaggttctcc agcatttatt caacgtaatg gctatgaagg cttcatgaag
     4921 cgagttacac cattgtggaa tttaagccat cgtacatact atgactatga atcagattca
     4981 tataaacatc cagttgaaca acctcaattg aaacaattcg ttgaatggtt gaaagaatta
     5041 cgtaaagata acgtacttca ccctgactgg gcagttatga aagatgaaac ttgggaaggt
     5101 ctattggctt ctaacaaggg ttcattcact gttgaccgta tgaatatcat tggagataat
     5161 aactttgata aatcatttga ttggcagcca cttgtttatc caaaaattaa tggaaaacgt
     5221 tatttgcaac cgaaaacacc gtacatttct gattcaggtt gggtaatcaa tgccaatgca
     5281 ccaaaagaag aaattgataa agcgttagaa ttctttaatt tcttatacgc tgatgaaaat
     5341 caagaaaaac ttgctattgg atttgaaggt aaaacattta cacgtgaaaa ccctaatact
     5401 caagcaggta ttaaatggtt gattcaaatt tacggtgaaa atgctggaaa tgataaagca
     5461 gaactgctgt ttaaacatgg taaccaagca tttactcgcg ttcaaactaa attagatatt
     5521 gaggcacagc caggaacatt ccctaaagtt atgtatgatc aagtagataa aattaagaaa
     5581 gatttaggtg gttttagacc agatactccg gttctttcct ttacaactga agaattagat
     5641 gttttaacta aatctgaagc aggattaaat actttctttg atgaaaatat tattaaattc
     5701 attgaaggac aaagagatat gagtgagtgg gattcattta tcaatgaagc taaatctaaa
     5761 gacttggata aagttacaaa agtatataat gatgcctaca aacgtgtcaa agatagaatg
     5821 aaatagacta aatggtagct ctctggtttt tcagagagct actactgcct gagggggagt
     5881 aagctttgta tgatgtagta attataggtg caggaagttc gggcgcattg gctgcaattg
     5941 cttcggggcg tctagggtta aaaacttgtc taatagagaa gggaagtaga attggtggag
     6001 ttcctattaa tacactaatg gggtcatttg ctaatctata ttttgatgat tctggtagag
     6061 taaatgcaag taaaattgtt ggggaattaa tagaacgtat tatcaaaaaa ggtggtactg
     6121 tctttaactc tatggaagaa ttgatgaatg taaatgattt ttatcagatt acaattccct
     6181 atcaaccaga agtttatgaa tcggttttaa ctgatatgtt gattgagtct aaagttgata
     6241 ttttactaaa tattgaagtt aataatatta tttatgatag taaaaatatt aaaagtcttg
     6301 aaattttaag taatcaggaa gttaaattga ttgattctaa agtttttatt gatgctacag
     6361 ggaatgcaac aattgcttct gctagtggag ctgatgttta tgaaaaaaat tcttcttacg
     6421 gttgtttaat gagagttgga ggagttgata tctcaaagac tatagaacat attgaaaaaa
     6481 caaagcagtg gaactatata gaaggatata atcagtggtt agaagaagta ttagcaaatc
     6541 gaaagtacag agccactgga gcagttttaa aagatccagt ttcttatgat catgccccta
     6601 tgctttcaaa agacgaccat tttatgaatg atgaaaaatg gaattacatt aaagaaagat
     6661 gggaaaaatt tagatttatt tacactttag aagtatcact atttaggaat gaattaaaaa
     6721 aaagctgtag aatctgggga ttttaatttt gaaatttatc atgatgataa atctggagtc
     6781 actatgaatg gcgacggtat aagctatggt tcatggggtc aaaatgtagc attaattaat
     6841 gttgcaaaag catttggatt caatcccaaa tatatggaag atgaatcaca tgctaatatt
     6901 ctttctagaa aatataattt aacattttta tcttttctta aaaaatatgt accaggtttt
     6961 gaaaattctt ttatccttga tcagggaact agagctacta acagatcatg taggcacatt
     7021 gataattcat ctatgatgga cgaaattctt gattttccaa tgtatacatt taagactatg
     7081 tatagctatc aaactcctaa agaaataacg tacaaatcaa ttgtaggtgg aaaattgaat
     7141 aatttgtttg taataggtaa aggtgcttac caatccgaaa gttttagatc acaaattagt
     7201 tgtatgttaa tggggatatc atcagcagca gcggcaaaaa ctattattga agataaaagc
     7261 aatactctaa acattaatag agatttgttt aaatcgaact tagatatatt atttacatgg
     7321 gagttttcta attggattac tgattaacaa ataataaggg aatattaaat gaatgatact
     7381 aataaaaatc aatactttgt ttatgaattt gatactagct ttgtagaaat gtcttattct
     7441 cagttttttg aaggatattg tattcttttt tcaaaagaac cctatccttc tttatctgat
     7501 atgccaatgg aatttagaaa agaattttta atggaaatga gtatattagg tgatgcgatg
     7561 cttgaagtgt taaatgccta tagaattaat tatgatatct taggaaattc aacacctgta
     7621 cttcatgctc atttatttcc gagatacatg tgggaagagg aagagagaag aaaaactgta
     7681 gttcatagat atgattcttc agtttttagc aatcctgagt ttgaatttac tatagaaaag
     7741 catggaccaa ttattaaaaa actgaggtct gctattgata gacattatag agagtatcaa
     7801 caattattag atgattcaaa ctgaactcca cattttcgat tagatttaat accttgtata
     7861 ttacaactag gttgtggatg atataatttt ttgaaaaata tattttagga atgacttata
     7921 aagcaattat atcagaggct attaaatcaa tggccaaagc ttatgctcct tattctgatt
     7981 ttaaggttgg agctgcgtta gtaactgaag ataaaaaatt ttttctggat gtaatataga
     8041 aaatgctgct ttttctccta cttgctgtgc agaacgagta tctttttata aagctgtatt
     8101 taaaggagaa cgttcgtttt caagaatatg tattgtaggt ggaaaaaatg gtatcttatc
     8161 atcttttata gcaccttgcg gagtgtgtcg ccaggtaatg atagaatttt gtaattctga
     8221 ttcatttgaa gttatattgg ctagtgatgt tgatacttat aaagtatata aacttaaaga
     8281 actactacca gttagtttta atcaagaaaa tttataacag gagggaacta tggaattagt
     8341 tgaatttaaa aatggacatg ttaatacggt tcatgagcat atcgcaataa cgaaagtaaa
     8401 agagtttcta aataatcatg atataccaaa agataaaggt ggcatacata aaatttctac
     8461 tgatttcttt tacaatataa ttgatatgga aactacaact gaagagaata gaccgtggga
     8521 aagtcataag gaatattatg atgtccatta tctgttaaat ggagaagaaa taattttata
     8581 taatttcttg tctcaaatgg aattgtctga atataaagta gatgatgatt ggcaacaaat
     8641 gaatgggaca gctttattta gtattaaatt aaagaaagat atgttacttt tgttggaacc
     8701 aaacgatgca cataaaacag gcctattggt tgaagaacca cttaatatta agaaagttgt
     8761 ttttaaggta aaaatttaac tgaaagtact ttcggggatt aagaatttta aaatatttaa
     8821 gaaattgtat tctaaagttc taaaattata gatatttaat ttaaagcttg ttaaaataga
     8881 atagt
//
LOCUS       DAVHKZ010000063         8404 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000063 DAVHKZ010000000
VERSION     DAVHKZ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8404
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.063"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(258..1484)
                     /locus_tag="VVO74_002074"
     CDS             complement(258..1484)
                     /locus_tag="VVO74_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU5696040.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVTQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(1484..3997)
                     /locus_tag="VVO74_002075"
     CDS             complement(1484..3997)
                     /locus_tag="VVO74_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEU5696041.1"
                     /translation="MDRLQTMLNKIQVDTYHKNGWLFVKYSNNKLTQGWKLHVSSQLK
                     DACNIFYIVAQELEKERCNYKVLDCLDELKKLNSPREVSPTANKFITIYPSSRKQAKR
                     IILNLKEKLEKYKAPRILSDFQCGEYSPIHYRYGAFKAIKNYNFSENKIVYMMKNSRG
                     ELVEDLRLSYPYLPEGVKDLFTDMEKNKLFKPSPEIPENHPLNHYNIECILKKSNRGN
                     VYRAIEKSSNQKVIIKHARPYVYSWNDGFSAIDELKSEAANLKVFQDKSYTTDLIEEF
                     YVNEDYFVVQKFIPGYNFFDLKNIDIEKNVIINNIIDIINDIHAEGYLAVDISPTNFI
                     LDDFGRVRLIDLENFTNKNNTVRRAATKFMINTDCPSKICTIQQDYFALAMLSFAIMR
                     EHVLIFEGEDVLLNITALDKIKFCMYSEKEIGNITKSQFNWLMYLLNLSEQEKLDRFE
                     KMKYINDFEDKNIEFHLKKVDSSFNLQIENETLINYLLSLNMNRESRILNSNEFGEFV
                     SPISFQHGLSGYLFYLSHMRDISENGRIIEWIISEGNQNKGNVYLNGCSILFGSSGYL
                     WVLLEFYKKITSNNPSRELIIDKIRDIYKDLISSYQKVEVFDFALGKSGILLSLMKYC
                     INFNDVDSMEFIREKIEELYLYFVDEIRNVNSLKECNFAHGLAGIAYVILIYNSEFEF
                     KVAYENSIKVFNNLLENLLENEYSRLNATPTNLELSWCEGTSGILLYFELLYDKRYSN
                     IISRFQQLAFKFNLIQSSCYCHGLSSLLQTLNYQDKLNLRENVIEILLSRSKRDKNGI
                     LVFECEESSDTLFDFGIGNLGIYWSILGERFPFELKKEL"
     gene            complement(4082..4294)
                     /locus_tag="VVO74_002076"
     CDS             complement(4082..4294)
                     /locus_tag="VVO74_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696042.1"
                     /translation="MRFSKISQFPCYTVLVKHLKQILGRRSGLQKNNQRRKEMHNLME
                     LELLPEEPVITVSREVCKWTCSFTAL"
     gene            complement(4463..5326)
                     /locus_tag="VVO74_002077"
     CDS             complement(4463..5326)
                     /locus_tag="VVO74_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU5696043.1"
                     /translation="MIERMELGEFYKELRLARKLKQSDVACEGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRKVVDRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYVPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            complement(5721..6892)
                     /locus_tag="VVO74_002078"
                     /pseudo
     CDS             complement(5721..6892)
                     /locus_tag="VVO74_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            complement(6905..7654)
                     /locus_tag="VVO74_002079"
     CDS             complement(6905..7654)
                     /locus_tag="VVO74_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEU5696044.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCSDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIIFWIKK"
     gene            complement(7666..8377)
                     /locus_tag="VVO74_002080"
                     /pseudo
     CDS             complement(7666..8377)
                     /locus_tag="VVO74_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000399185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2878 a         1493 c         1157 g         2876 t
ORIGIN      
        1 tttcgaagag tataagtagg ctgaaaagaa tccagccaca gcatggacta ttatatagca
       61 gattgaaata agatgagaac aaatcgattg ggaaagtaaa attaatttct ataaataaat
      121 gttttagcaa ttgtttcgta ctattttaga ttcagtctat tataacacat tcagaaaaga
      181 gaaaaaagtc tgttgatttt gaccatcata aaaaggctgg caatccagtc tcaaacatat
      241 attatagaaa ttctccacta aatactttca cgaatattca gaagcataac aaaggcaact
      301 agaagaaata gcaataaaac aaagctaact gccagagttc caaagctagt agcaatggtt
      361 accaaagcta ttgtaaataa gctaggtaaa acaaccgtaa tggcaccgat agaggattga
      421 actgctccca ttgactcctc aggtatttgt ttaaaaacga gttcttgcaa tctaggagag
      481 agaacacctg cgaaaaaggc atccaaggta ctaaagatga gaatccagtc aaaacgaact
      541 gtggcaaatc ctactagaag aagcaactgg gtgacaagtg aggcatagag agctgttttt
      601 atggaaatgg tatgttgcag atagccactt acaaggcttc cgacaatcag ggctgacagt
      661 tcaaaagtgg atagcaaggc aagagattga cctgtttgta aattcaaaaa gggttgattc
      721 ctcaaaaata gagtagagac aggaactgta acatttatca ctgcttgact agtagagata
      781 ataaacaaaa ccaagagcac cttattcata ttccatatca atttcgatga ttggagcaaa
      841 tgctggcaaa aggattttac agagagtcct tcttgatagt taatcgtttt ttctactttc
      901 aagaggtcag tttttatgaa gaggatacct aaaaatgcga ttaaaaaggt aagagcgttc
      961 agcaaggaaa taaactggat ggatagaata cctaataaga ctcctcctag aatattactg
     1021 attgttttca ctaaactaac agttgactgt ttaaatccaa tagcttctgc cagatggtct
     1081 tgcccaataa ttctaatgaa aatcggagtg agcatggcgc ctgaaaaata actcaacgtg
     1141 tcagacaaga ggttaatcag acaaataaat gctactaata acaaggaaaa ggactgccct
     1201 gaaagtgata aagacactat agagtaaagc aaaaattttg caaaactaat gactgtgtat
     1261 ttcaagacac gatgatgttg aaaatccgcc aaaactccca gaaagatttg tagaacttgg
     1321 ggcagggttt ctgaaatcgt gatgagtaaa atcgccaaag gggcaaaaga tgcatctgcc
     1381 acataattca ggaaggccag ataaaaaatc gtatccccaa gcgttgaaat ccactggttg
     1441 atagttaatt gcctaaaatc tctattttga agaaatactt tcatcacaac tccttcttaa
     1501 gttcaaatgg gaatctttcc ccaaggatag accaataaat ccctagattt ccgataccaa
     1561 aatcaaataa tgtatctgaa ctttcttcac attcaaatac caaaatacca tttttatctc
     1621 ttttggatct acttaataaa atctcaatca cattctcacg taaatttaat ttatcctgat
     1681 agtttagagt ttgcaacaaa ctggataagc catgacaata acaacttgac tggataagat
     1741 tgaatttgaa agcaagttgt tgaaaccttg aaattatgtt tgaatacctt ttgtcatata
     1801 ataactcaaa ataaagtaag attcctgaag ttccttcgca ccacgatagt tctaaatttg
     1861 taggagttgc atttagtcta ctatattcat tttctaacaa attttctaac agattattga
     1921 ataccttaat actattttcg taagctacct tgaattcaaa ttccgaatta taaattaaaa
     1981 ttacgtatgc aattccagct agaccatgtg caaaattaca ttcttttaaa ctattaacat
     2041 ttcgtatctc atctacaaaa tataaatata actcctctat tttttctcta ataaattcca
     2101 tactatcgac atcattgaaa tttatacagt atttcataag actcaataaa atacctgact
     2161 ttcctaaagc aaagtcaaat acttcaactt tttgataact acttatcaag tctttataaa
     2221 tatctctaat tttatctatg atcaattctc tacttggatt gttgctggta atttttttat
     2281 agaactctaa taatacccaa agatatccgg aagaaccaaa taaaattgaa caaccattta
     2341 gatacacatt tcctttattt tgatttcctt cagagataat ccactcgata attctaccat
     2401 tctcagaaat gtctctcata tgtgataaat aaaacaaata tcctgataag ccatgttgaa
     2461 acgatattgg actaacaaat tctccaaatt catttgaatt tagtatcctg ctttctctat
     2521 tcatatttaa cgaaagaaga tagttaataa gcgtttcatt ttcaatttga agattgaatg
     2581 aggaatcaac tttctttaaa tgaaattcta tatttttatc ttcaaaatcg tttatatact
     2641 tcatcttctc gaatcggtct aacttctctt gttcacttaa attcaataaa tacatcaacc
     2701 aattaaattg cgatttagtt atgttcccaa tttctttctc gctatacata caaaacttga
     2761 ttttatctaa agcagttata tttaataaga cgtcctctcc ttcaaatatt aaaacatgct
     2821 cgcgcataat agcaaaactc aacattgcaa gtgcaaaata atcctgttga atggtacaga
     2881 tttttgaggg acaatcagta tttatcatga attttgtagc agctcttcta acagtattgt
     2941 ttttgtttgt aaaattttct aagtctatta acctaacacg accaaaatca tccaatataa
     3001 agtttgttgg agaaatatcc actgctaaat atccctcagc atgaatatca ttaataatat
     3061 caattatatt attaatgatt acattttttt cgatatcaat attttttaaa tcaaaaaaat
     3121 tatatcctgg tataaacttc tgtactacga agtaatcttc attgacataa aactcttcaa
     3181 ttaaatctgt tgtataggac ttatcctgaa atacttttaa atttgctgct tcactcttta
     3241 attcatcaat tgcagagaaa ccatcattcc aactataaac atatggccgt gcgtgtttta
     3301 ttatcacttt ctgattacta cttttttcta tagctctgta aacatttcct ctattggatt
     3361 tttttagaat acactcgata ttatagtgat ttaaagggtg attctctggg atttccgggg
     3421 agggtttaaa taatttattt ttttccatat cagtaaataa atccttaacc ccttctggca
     3481 aatatggata acttaatctc agatcttcta ctaattctcc tctactattt ttcatcatgt
     3541 agacaatttt attttcagaa aaattgtaat ttttaattgc tttaaacgca ccatatctat
     3601 aatgtattgg agaatactca ccacattgaa aatctgataa aatccttgga gctttatatt
     3661 tttctaactt ttcttttaga tttaatatta ttcgtttggc ctgcttccta ctagacggat
     3721 atatagtgat aaacttattt gcagtaggag aaacttccct aggagaattt aattttttta
     3781 actcatccaa acaatctaga actttgtagt tacatctttc cttttccagc tcttgtgcaa
     3841 caatataaaa aatattacaa gcgtctttta gttgactgct tacatgaagt ttccatccct
     3901 gtgtaagttt attgttacta tacttcacaa ataaccatcc atttttatgg taagtatcaa
     3961 cttgtatttt attcagcatt gtttgtaatc tatccataaa tataataaat acattatctc
     4021 tgaaatgaaa ttaaggatag ttaattagta atcaactatc cttaatttta accagttatt
     4081 cttaaagagc agtaaatgag caagtccact tacaaacttc ccgtgataca gtaattactg
     4141 gctcttcagg taacaattca agttccatta gattatgcat ttcttttctc ctttgattat
     4201 ttttttgtaa accacttctg cgacctagga tttgcttcaa atgttttaca aggacagtat
     4261 aacacggaaa ttggcttatt ttagaaaatc gcatatttga tattttttct tatagaaatt
     4321 tcagatttgc gattttggta gatttgatta tttccctggt ataataaagt tattactaat
     4381 gaggagggaa gtaatatgaa gaaacaagtt ttaacattat tgacgatcgt tgctgatatt
     4441 attatctttt tcccatttct aactaatcga taagctcttt gtattgctgc aaacgcaatt
     4501 caaaaagggc tgtcaattgt ggattttcta atacttgcag agattggata aagtgttcaa
     4561 tctctttttg attgcttcct ttggtttgaa gaaaaatctg cattttcttt aaaaactgcc
     4621 acaatacttt ttcaaaaaca tcgtatggac ggagcatgcg ctccagctca gcttcaaaga
     4681 ttggaacata agaaaatagc ttgcgctcca taagttctga gatgatatta agataaccac
     4741 ttttcatata ccatcgattg tgtactaact ctttaaattc cttggatttt tcgagtaagg
     4801 aggttgataa aaagatcaga tcttgattgc tcaagaaggg catagtattg caaaaaagat
     4861 agagttcaaa ccaggtccaa gactcaatag cgtagaggta ggtagtcaaa aactcgctat
     4921 cctcctctgt tagcgggtag cttttatcta aggaatggag tgcattttta atcacaatgg
     4981 cattcaaacg acgataggtc tgcgccatct gttcttgatc gacttcctcc aatagctgct
     5041 ctaaagcagc tatatcctga tgggcaaagc gatccacaac ctttcgaccg attcgcatat
     5101 gtggagattc ttgatagttg ttgagcttgt gcccaaactc atcaaaattc atattgatcc
     5161 cttggatggc taatatgagc ttatctgcag ataacataga ctgtcctagt tcaaacttgg
     5221 acaactgaga agctgttaga ccctcacagg ccacatctga ctgcttaagt tttctcgcca
     5281 agcgcaattc cttgtaaaat tctcccaatt ccattctctc aatcatctga ccacctccta
     5341 gcttttgcat attatatcat tatttacaat catttgtcaa aatattctga tatttaagag
     5401 ggcaaaaaag ccagccttaa gctgactcta aaaggaccga gccttgtaca atacagaact
     5461 caatcctcgt tctaaataga atgtctaact tttttgggca gtacacgagc ttggggaaca
     5521 gccactggaa cgatgaggtg tgagctcaaa atatcctcca gttatgtttt tcctaatagt
     5581 ataccggaag agtgaaagga ttttataatg gagcggttac aaagaaccta ctttctatta
     5641 aacagtatac tatgaaaatg tgaaaattta acattttttt gtacaaattt tataaattat
     5701 tgccttttta atatcaatag ttaatctctt atccagatcc cccttgtgta aactttatct
     5761 ttataagctt caaggcccct atcccatcta tttgcaacaa ttagatcact ttgttttgta
     5821 aatagttcaa aattcttttc aaaaattacg ttatctatac taacgtttaa atttggttca
     5881 tatactaaaa tttttatacc gacaatcaat agttcattaa ttatacttaa aatagctgac
     5941 tctttgtaat tatctgaatt atatttcatc cccaatttat atattcctac tatctttggc
     6001 tttcgttcca atatttgttt aactatgaac tgttttctat ttgtgtttga aatatcaatc
     6061 gcttctatca ctggggcatt tatttctata aattcttttt ttaattgttt agtatctttg
     6121 ggaagacaat atcctccaaa tccaaaagaa ggattattat aaaaatttcc aattcttgga
     6181 tctaaacaaa caccttttat tacaacttca gcatttaaac ttctcctctc agcaaaagaa
     6241 tctagttcat taaaaaagca acacggagag ctaagaatgt gttagaaaaa agcttaattg
     6301 cttctgcttc agtaggagaa actaacataa catttttaat attggcagta ctatgagtac
     6361 taatcgaaag gaacaactct gcaatttttc ttccttcaac tgtctcatct ccaacaacta
     6421 tgcgacttgg atataaatta tcatatatag aacaaccttc tctcaaaaat tcagggacaa
     6481 aaatgatatt ttttgtatca aacagccttt ttaatttgtt tgaaaagccg atcggaactg
     6541 ttgactttaa aataatcttt ccattaggtt ttaccctcag aatcttcgat accgtttgtt
     6601 cgatttcata tgtattaaaa ctaccaattt tctcatcata atctgtcgga agcgcaataa
     6661 tataataatc aatattattt ttaatttcag aaaatgtatc aaaaaaagta atatttaagt
     6721 tattctcgca aaaaaacttc ataagctctt catttttaga tggaagaatg ccctttttta
     6781 aattatttat ttttacagaa tctatatcat atgcaacaac tttatattta gatgcaaata
     6841 gtaacgcgta ggccagccca acatgcccca aaccaattac tgctatattc ataaaactac
     6901 ttccttattt cttaatccaa aatataatag aataagctgc cccattcctt aaatacaact
     6961 ctttaatatt gtttaaaagt ttttcaactg atttccagat tatcaaaatc tgagatttat
     7021 agcacaatat tgatgatatt ctatcaatat aatgtttttc atcaagttcc tcttgataca
     7081 tttttaattc tttagttttt cccatataac taaccatact actatcactt acatatggga
     7141 aatcctcata atatattact ttataacgca taaattcaag cgcccttcca atactattca
     7201 caaaaacatg atcaacatgg tcaccaagtg aaagcggaca atatacgaca catttatcgt
     7261 ctaaatgcat taacagctct tttatgatat cattctttaa tgtgtcctca ttttttaatt
     7321 cactatagat atgacggtat agaaaattgc catttctatc tttcctatag agacattcat
     7381 agtacgataa gtgtctaaaa tcacattgta gacgttcaca agctaacctg tcttctttct
     7441 tcctttcttc aatcggatat ttcccaaggt tacacaactt atgaaattgc ttagcagagg
     7501 gctgtagctg ttggctcaaa gggtaaccag aaaatatagt aataacaagt acaatttctc
     7561 cttctgaagt taattttgaa atataatcac tacaggaaaa aattgcgtca tctaaatgtg
     7621 gagataaaaa gatatactta gtattgttac tcataaccat tccctctaca atttatctaa
     7681 aaactcacta agtgtctgat taaattccac atcatcaaaa aaattcacct tattcttaat
     7741 aatgaatatt tcgttaaata aacatatata taaatatttc aatatccttt caatatcatc
     7801 ctctaaattc tcctcaatat tttgtatcag cccatttaca atcttattaa aaaagataag
     7861 ctctttatct ctaaaattaa atattttcga tacaactgtt gtatcgaaaa atatataaaa
     7921 taatttttac taatgtttga atatttaaac aactaaataa atgagttgta cccgggacac
     7981 tatttatgtt atcaagaaca ctatcttgaa acctcaactc acagttcttt ttgtgaaatt
     8041 cttttttatc gtttaaatct gatatttttt tagacatttc aacaatctca gacattttat
     8101 atggatatct aggatgaatg ccaaaactat gcaaaagtag gctatttttc tttaaaacaa
     8161 ttgaatttgt aacataaaat ggatagtcgg aataactaaa atatactgac ttctgtttat
     8221 cattacaaaa ttgattgtag ttcacagaat gatacttaaa agtcattatt tcatccgctg
     8281 actcgccaca aagaatactt gtgttccctt tttggaacaa caacctgcct aaatagtact
     8341 gcagtatgac accacattca aagagacttc cttccaatct ccatactata tcgggaaaat
     8401 attc
//
LOCUS       DAVHKZ010000064         8372 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000064 DAVHKZ010000000
VERSION     DAVHKZ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8372
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.064"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(627..935)
                     /locus_tag="VVO74_002081"
     CDS             complement(627..935)
                     /locus_tag="VVO74_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU5696045.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(932..1240)
                     /locus_tag="VVO74_002082"
     CDS             complement(932..1240)
                     /locus_tag="VVO74_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU5696046.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1245..2540)
                     /locus_tag="VVO74_002083"
     CDS             complement(1245..2540)
                     /locus_tag="VVO74_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU5696047.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2558..3967)
                     /locus_tag="VVO74_002084"
     CDS             complement(2558..3967)
                     /locus_tag="VVO74_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU5696048.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4125..4853
                     /locus_tag="VVO74_002085"
     CDS             4125..4853
                     /locus_tag="VVO74_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU5696049.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5312..5506
                     /locus_tag="VVO74_002086"
     CDS             5312..5506
                     /locus_tag="VVO74_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU5696050.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(5872..7182)
                     /locus_tag="VVO74_002087"
     CDS             complement(5872..7182)
                     /locus_tag="VVO74_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU5696051.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGKTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7419..8291
                     /locus_tag="VVO74_002088"
     CDS             7419..8291
                     /locus_tag="VVO74_002088"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU5696052.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFKRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALDDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         2607 a         1465 c         1587 g         2713 t
ORIGIN      
        1 gatagagttg ttcacatctt atttcaattc actatagttt aatttaagag tagtatttac
       61 taaggcccaa ttaaaatcaa agagcaaact agaaaacgag tgccattcag ctcaaaacac
      121 tgatttgaga ttgcagataa gactagcccc ctcattaaca gatttacgat aaaacgatga
      181 caaggtgtgt tgctttttga tttctaaaga gtataatgat agatctctat aaaataagtg
      241 cgaaggaaat gagcttttat agtcctttcg ttttaaaata ctatctcaga tattcttata
      301 tcgacaagaa gtttttgagt cattccctca tcatacatat taaataaata gtggctcatt
      361 caatttttca ctagaataat aagctagtat agtaaactga aataagatat aaacaaataa
      421 attggagctt aacatccatt tccagcaatt ttttagaaac tacagtggac tattctagat
      481 tcaacatatt ataaaaacta gagtaaaaga aaaggattgg atcttgtgta atgcaggatc
      541 caatcctttc aatcattttg tccaactttt ggaggttcct acaatgtagt cgtcattaat
      601 aaagacagat gggaatgaca gtgttcctat ttattttgat agagatcgat gaattcttta
      661 gatagcaact gaataatctc tgttgaagcc atttggtctt ctgcatgcat aaatagcaag
      721 gagaatccta ttttttctcc agtagcttct ttttgtatga gattagagtg aatcttgtgc
      781 gcttctacta aggagtcttc cgcttcttca actttaattt tcgcttcttt taaatttcct
      841 gccttagcta gttggatggc ttcaataaag gatgatttgg ctgctccact attggcaatg
      901 agctgaaaac agatatattc catttcttct gtcatcttat ttctcctatc catgcaagtg
      961 cttgttccag aacttttgct ccattcatca ttccgtaatc ccgcatatca atggtatcta
     1021 cagggatatt tcctgcaatt tctttcacag caagtaactc ataacgaatt tgtggcccaa
     1081 ttagaatgac atctgcttca tggatattct ttttagcttc tgtcattgat tttgcttgga
     1141 tagagatttc aatcccacgt tcagtcgcac tttgttgcat ttttttaaca agcatacttg
     1201 tcgacattcc cgcattacat actaataaaa tttgtttcat aatcttaacc ttccatttct
     1261 tgttcaacaa ctttgtcatt aactttgata aatggaatgt atagaagaac tccaagtgca
     1321 aagatgatga attgaactag aactgctctc acgtcccctg ctgttgctaa ccatgcattt
     1381 aagaatactg gtgtagtcca aggaacttgt ataaatgcag gactcatgaa tcctgtaact
     1441 gttgctaagt agctgattaa aataccaagg actggaactg tgataaatgg aatagctaat
     1501 gaaatgttat aaacgattgg gtaaccgaat aatactggtt cattgatatt gaagatacca
     1561 ggtccaaaag ataatttagc cacgttttta gagacagcat tgcgactcac taagaatgtt
     1621 gctattaata aacataatgt agatccacta ccacccatta aagcgaatgt ttgtatttgt
     1681 gataggttga tgatgtgtgg aatggcttgt ccattatttg ctgcagtgat gttttcagta
     1741 atgttaatta atagtaatgg ttctaggatg gcactgtaaa taactgcttg gtgaatacca
     1801 aatagccata acatatttcc taaagagtaa ataataatga ccccgattaa gcttgtacca
     1861 atatgacgaa ttggttcttg aataaagatt gtaatgattg agattaagtt cattccagtt
     1921 atattgaata ataatgctga aacaacccca aataaggaga tgacggtcat gactggaagt
     1981 aatacgctaa atgatctact aacagctggt ggaatatttt caccaaggtt catttgtaaa
     2041 gctttaacgt ttgataattc aatgaataat tctgttgcaa taatcgctac gataaccccg
     2101 gcgaacattg cgcctgtacc tgtgttgttg aatgaaagaa cacctgaaat gtttacagca
     2161 tcttttgctc cgtcaggaac tacagaaact gtatttggca tcatcacaat taaagaaact
     2221 aatgatagca ttgatgctgc taacgggttt tcgaaatctc tgtttttagc taagaaataa
     2281 ccaaccatta cagcaataat catacctgaa atacttaaag taccgtttgc aattgttatt
     2341 ccccaatatt ggaattttgt taatgtatcc ccttggaaaa tccacttaaa taccgtgttg
     2401 ttcaaaagaa cgattaaacc tgccaaaata tataatggca ttactgttac gaatgcatct
     2461 cttagggttt ttaaatgaat ttggttccct agtttaccag caaaggtggc aaattgatct
     2521 ataaattttg agtttttcat ctgaatatct cctctcttta ctcctcaatt tctacttcaa
     2581 aaccgttatt gtcacttact ttgcgatacc atcttcctga gctcttgatg gttctctttt
     2641 gcgtttctaa atcaacggag ataaatccgt aacgattctt atatgcatta ttccaagacc
     2701 agcaatcaaa tgcggtccaa gcgtggtatc caaaacagtg acttccctct tcaatggctt
     2761 tatgtagcca tcttaaatgt tcttcataaa attcaatacg atacacgtca tcgataactc
     2821 cattttcatc gataaaccgt gcttcgtttt caacacccat tccgttttca ctgataaacc
     2881 atggaatatt atcatattct tccttcacaa tcatagcaat atcataaatg gctttcggaa
     2941 aaatttccca accacgatat ggattcatgc gacgctccgg ccattcatac tctttgaagt
     3001 attggtctgg catccagggc gtctgatatt cctcaggatt tgcttgtgct tgaacacgtt
     3061 ttggatggta gtagtttact ccaagaaaat caaccgtatt tgatttcatc agttgaagct
     3121 ctttttcggt atgactccat aacacgccat ctctctctag ctgttttacc aatctttctg
     3181 ggaaagttcc tttaacagct ggattcaaga agactttgtt aaagaagtct tctgtaaatc
     3241 gacttgcttc taagtcttct ggagaattac ttcttggata agcaggtgtc aagtttaaaa
     3301 taatcccaat ctttccatca agtcctaatg agcgatatag ttgaatcact tttgcactag
     3361 caaggtttag attatagatg acttgtacgg cctcttttcc ctttcctttt agatttggat
     3421 aatggaaagc atataagtat cctgcttctg gaatgaccat tggctcattg aaagttgtcc
     3481 agtaatgaac cttatctcca aagcatgtga aagcagtctt ggcaaacttc acgaataact
     3541 ccactacatg tttgctttcc caaccaccgt atttttgaag aagttccact ggtaaatcaa
     3601 aatgatgtaa attcatcaca agatccatct ggttcttttt agcttcttca atgatggcat
     3661 tgtagaaagc aatacctttt ggatcaggct cacctgtctc taaattcttg atgagtcgac
     3721 tccattggat ggaagtgcgg aaagaattaa ctccaatttc cttcatcaag tggaaatctt
     3781 cggtgtaagt atgaaaaaag ttactggcta caagaggtcc gacattatcg aaaaaatctt
     3841 ctggatgcgt tttgaaccag tagtccatca cattttcatg tacttttcca tattgacctt
     3901 ctgtctgagg tccgctagaa gcagctcccc accaaaacag attaggaaat actaactttt
     3961 ttttcatgct caacctcctt tctattattc tatacataaa gtatagcata attttaaaat
     4021 ttgtctagac atttttaaaa attgttgata catgtcttgt gtttgcctca tttcttgaac
     4081 tttgttatac tactattaga atattataga gagaaccaga ttaaatgagt acaaaatatt
     4141 tatttattta caatgagatt cgtgaaaaga ttctttgtaa taaatatacc atgaacgaac
     4201 aattgcctga tgaaatgaca ttagctaaac agtttgcctg tagtcgaatg acgatcaaaa
     4261 aagctttaga cttgttagtt tctgagggct taatttttag aaaacgtggg cagggaacct
     4321 ttgttctctc tcgtggcagc tcaaaaagaa aattaatcgt tccagaaaga gatatccggg
     4381 gactgacaaa aatatctgaa gatgctcatt ctacaattga ctcgaggatt attcacttca
     4441 aattagaatt tgcaaatgaa tttttagcag aaaaactaca ggtcgctttg cagagtccag
     4501 tttataatat ttaccgtctg cgtattattg acggtaaacc ttatgttctg gaacaaactt
     4561 atatgagtac cgatgttatt ccaggtatta ctgaagatat tttacaaaaa tcgatttaca
     4621 attacattga aggaaagtta ggattgcata ttgccagtgc tacaaaaatc ttgcgagctt
     4681 cttctagttc agaaaatgag caacattact tgcagctcct tccaacggaa ccggtatttg
     4741 aagtagaaca agtggcttat ttggataacg gaactccgtt tgagtactcg attagtcgtc
     4801 atcgctatga tttatttgaa tttaattctt ttgcattacg acattcctcc taggagaaaa
     4861 tgtgaaaatg aagccaatct tttacagact ctagtttaag aaaaatttaa aacagggcaa
     4921 gaaggtccca tctatgctta aatggtttct cttttctaaa taagatagct ttaaaagagt
     4981 gatcgtttta tccatcatgt tgaaaaatat cttcgtatag cttatagagt aggtactgaa
     5041 attgttcacc tgatctactt cttatagtta tttagtttta aatagtgttt caaacattct
     5101 tacactgacg agaagttttt gagtcttttc ttgtaacaca tatagtatac tgaggttaga
     5161 atagtagact gtgacttcta aaaaattgct agaaatgaat ttcaatctcc caatttattt
     5221 gttcatatct tcttttaata tattaaataa attctgaatc ataatcattt aaaaaaattt
     5281 tattttttat ttttcattac gaataatata gatgaagggg aaagagtatg aaaacagaac
     5341 tgtttctttt gctattagtt caaaaggaga aaaaatgaaa gtagaaaata tttcgtatag
     5401 ggtggatcat cgtatattgt ttgataatat ttcttttgat acttcgagtt caggcgtgac
     5461 attaattact ggtaaaaatg gtacaggaaa gtcaacttta ctatagtaga ttgaaactag
     5521 aatagtacac atctacttct aaaatattgt tagaaatcga tttgactatc ctgatctatt
     5581 tgtcctgttc ttatttcatt tcactacatc tcaaattgag tatgacgaag tgcgctccca
     5641 tgtcctggga acgcactttc ttcatatttt tcatattctt gaatccatcg ataaagacta
     5701 ttgggatgaa tttttaaagt tgaactaatc atttttacag gatgaggttt acagcagaga
     5761 gtttgaaggc tttatcaaag gtttttcttg gcataatgac ttttcctcgt ttccacttaa
     5821 ttttgtgtct actttattat accaagtcca cccttaagtt agataataaa tctaacttaa
     5881 ggaagctaga aggatgagaa tccaggtggt caagagtccc aaacttaagc tgatggggac
     5941 acccagaata atttgctttt tgaaggcaag gccacgttcc tctatattgg gaagtgagag
     6001 ttgaatgaga gaaccagctg atgaaaaggg tgagatatta gtagatagag cgccaataac
     6061 ggtggctgtt gtgagtaagt gaatatcaat ctggggattt tgagcactga tgatagcaat
     6121 gatgggaaag agggctggag ctacaacgga tagggtggaa ctaaagagtg acatcactcc
     6181 ggctatcaca caaaagaaca gaggtaacca gaaatgagga atggatgttg tcatgaggtg
     6241 ccctatcagt gtgactaaac ctgacttgac cgctagagac attagtaagc tcatgccgca
     6301 gagcatgata attgtagccc agggaacctt agctaaaatg gcttcttgct tccctaattt
     6361 gagccttaag gcgaggcaga ccatgagtat tgagacaaag ccaatatcaa atgttttttg
     6421 ataagtagct atccaggcga tgtttgggaa aatgagatgc aacaagggaa aaagccaaac
     6481 caaaaccatg ctgctgatca tgagcaaggt ggtttgtctt tgaaccttgc tgaggagtgg
     6541 tggttggtca atagtcaagg atgagtttgt ttttccctta ctatagtgac tgtaacagga
     6601 taataaaagc aagacgatga gtgggtagat aatgctgacg ataaagatat gattgccaag
     6661 tgaaaaagct tgctcttccc atcccatttg cttaaacagg ccttgaaaga caatgcctga
     6721 gctactggtt atcaaattag cccctcctga agctccccaa ttgacggctt gagctccaat
     6781 caaagggtgt ttgtccgctt tttgacagag ggtaatcgct agaggacagc aaacggccat
     6841 agtagtgaaa aatccagcac ctaaagcaga caaaagggtt gccatcaggt ataaaatcat
     6901 gtagagggcg ttagggtagg tgcgtgtgcg gtagagaatg tgttgagcca aaacatcaag
     6961 agtaccgtta gttattgcaa agttataaaa gagagagacg ctaaaaatgg taaaaaagag
     7021 tgaggttggc caaaaatgaa gaagttcttt ggggcttaat cccatgagag tggttgcgat
     7081 gaggtaagaa aaagcaatag ccagcaggcc aatattgatt ttggtgcggt aaccaattcc
     7141 aatggctaga gcaatggcgc taatcattat taaatgaatc attgaattgt cctttcagtt
     7201 agaatatgga aataggttgg caattttggc gctcaaaaga ccacctgttt cctattggta
     7261 cttgactatt atacacaaaa aaaatacaat tgtcttgaca attgtattga cacttgttag
     7321 aattaaaaat gaggtattca ggcttgtgat ttcctatgga agttaatagt gattgcctct
     7381 aatgcttaca agtgatatta aaaatagagg acttagtgat gtcaatcatt tcaactgatt
     7441 taaccccttt tcaaatagat gatacattga aagcagcctt gcgagaagat gttcattccg
     7501 aagattacag taccaatgcc atttttgatc atcatggcca agccaaggtg tcgctttttg
     7561 ccaaggaagc tggtgtttta gcggggctaa ccgtttttaa aagggttttt accctatttg
     7621 atgccgaggt gaccttccag aatcctcatc aatttaagga tggggatcgt ttgactagtg
     7681 gcgatttggt tttagaaatc ataggctcgg tgagaagtct cttaacatgt gaacgcgttg
     7741 ccttgaattt tttacaacat ttatcaggga ttgcttcgat gacagctgct tatgtagaag
     7801 ccttagacga tgattgcatt aaggtatttg atactcgaaa aactactcct aatttacgtc
     7861 tttttgagaa atatgccgtg agagttggcg gtggctataa tcatcgcttt aatttatcag
     7921 atgctatcat gctaaaagac aatcacattg cggcagtagg tagtgttcaa aaggcaattg
     7981 ctcaagcgcg tgcctatgct ccttttgtga aaatggtcga ggtggaagtg gaaagccttg
     8041 ctgctgccga agaagctgcg gcggcgggtg ctgatattat catgttggat aatatgtcat
     8101 tggaacagat tgaacaggcc attaccctaa ttgcaggacg ttctcggatt gaatgttctg
     8161 gaaatattga tatgaccact attagccgtt ttcgtggttt agcgattgat tacgtctcca
     8221 gtggtagttt aacccatagt gctaagagtc ttgatttttc catgaagggg ttaacctacc
     8281 ttgatgtcta agttgtaaaa taaactaact ttttaaagga tgtctttcct ctagaacgag
     8341 ttttatgtca gatagtttaa acgcctcttc aa
//
LOCUS       DAVHKZ010000065         8159 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000065 DAVHKZ010000000
VERSION     DAVHKZ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8159
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.065"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(147..1232)
                     /gene="rlmN"
                     /locus_tag="VVO74_002089"
     CDS             complement(147..1232)
                     /gene="rlmN"
                     /locus_tag="VVO74_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEU5696053.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMTIGARHITVSTLGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDSVEQALE
                     LTELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(1253..1783)
                     /locus_tag="VVO74_002090"
     CDS             complement(1253..1783)
                     /locus_tag="VVO74_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU5696054.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(1939..2544)
                     /locus_tag="VVO74_002091"
     CDS             complement(1939..2544)
                     /locus_tag="VVO74_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU5696055.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(2717..3754)
                     /locus_tag="VVO74_002092"
     CDS             complement(2717..3754)
                     /locus_tag="VVO74_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU5696056.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(3788..4723)
                     /locus_tag="VVO74_002093"
     CDS             complement(3788..4723)
                     /locus_tag="VVO74_002093"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU5696057.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(5276..6466)
                     /locus_tag="VVO74_002094"
     CDS             complement(5276..6466)
                     /locus_tag="VVO74_002094"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU5696058.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(6681..8024)
                     /locus_tag="VVO74_002095"
     CDS             complement(6681..8024)
                     /locus_tag="VVO74_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU5696059.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
BASE COUNT         2376 a         1791 c         1496 g         2496 t
ORIGIN      
        1 aaaaaccagg cgtccaagat gctgaatacc tggagttccc actcccacgg tagattgttc
       61 ttgaggagta aagcaaaaac agacaatgca aatgctatag aaaatgactc cccagaccaa
      121 aatatgatta taagtcttct tcatcattaa ggatttaccg ctgcgactgc cttctggcgg
      181 tcacgtttca ttgtgttaga gcgcaattgt ccacaagctg cgtcaatatc tgtaccatgc
      241 tcttgacgaa ccacacagtt gacccctttt ttcttaagcg tatcatagaa agccaacacg
      301 cgctctttgg gactacggct atattggtca tgctcactaa ctgggttata aggaatcaag
      361 tttacataag acaatttctt gatgttcttg agcaattcag tcaattccaa ggcttgttct
      421 acactgtcgt tgacttcatt aagcatgata tattcaaagg ttacacgacg gtttgttgtc
      481 tcaatgtagt attcaatagc agcaaagagt ttttcaatcg gaaaggcacg gttaatcttc
      541 atgatacttg aacgaagttc attgttaggt gcgtgaagag acacggcaag attgacctga
      601 accccttcat cagcaaagtc acgaatttta tgagccaaac ctaaggttga aaccgtgatg
      661 tgacgagcac cgatagtcat tcctttatca tcattgatag tacgaaagaa attcaagaca
      721 ttgttgtaat tatcaaaggg ctcaccgatt cccatgacaa cgatatggct gacgcgttca
      781 tcctgaccac gctcatcaaa gtatttctga accagcatga tttgcgctac gatttcaccg
      841 ttattgaggt cacgttgctt cttaatcaaa ccagaggcac agaaggtaca accgatatta
      901 cagccgacct gagtggtcac acagacagat aaaccatagt gttgacgcat gagtacagtc
      961 tcaattaaca taccgtcggg caattcaaag agatatttga ctgtaccatc agcagactct
     1021 tgcacaatac gttgtttcaa gggattgacc acaaactggt cattgagctt agcaatcaaa
     1081 tccttggaaa ggttggtcat ttcttcaaat gactgcacac gtttacggta gagccattcc
     1141 cagatttgat ctgcacggaa tttcttttct ccctgctcca atacccattc ctgcatggtt
     1201 tgatgtgcca aactatgaat tgagggtttc atttcttctc cttattctct actcacttct
     1261 gacgaatgac aaaatgacgt tgtcccttgt cctctttctg agaatgctgg tctttctgac
     1321 gacgtctatt cttcttatct gcattcgact ttcgtttagt ttgagtcggt ttctttcctt
     1381 ttctagaagg tgtttcttct tccgtcttac gcattttctt gtcaaatgat gctcgcttag
     1441 gggcttcatt ttctaagaca aaataggcac aaccataact acaatactct aaaaggtagt
     1501 cttgtaaacg actgattttt tcaagttttt cttctgttcg gtcatccttg taaaaacctc
     1561 gtaggcgaag ctgttcgttg ctccagtccc ccacgatata atcaaacttg gttaatactt
     1621 ctgaaaaacg ctgattaaaa gtcgtcacat caaaggcatc cttgatattt tcaaccaagg
     1681 aaaaagctat cccttccgtt tcgaccttgt ccccgtgtaa atggaactcc ggaccaggaa
     1741 acttgttata gttgtataat tcaggtgcaa tttcttttcg catagatatc ctttttccac
     1801 gattacttaa tactttattc taccataatt tctagcagtt agcacgtttc tcataaaaat
     1861 gaaaaaagtc tgacgatttt gtcagaccag aatcttataa cctaaaaaga gaagaacaat
     1921 tcttccctcc aactatcatt atttagcagc tgcgtacaat tcatctactt tattccagtt
     1981 gattactgaa aagaaagctt tgatgtagtc aggacgcacg ttgcggtatt tcacgtagta
     2041 agcatgttcc caaacgtcca agcccaagat tggtttttta ccttctgaga ttggtgtgtc
     2101 ttggtttgct gttgaagtca cttcaagttt cccttctttg ttgacaacca accatgccca
     2161 acctgaacca aaacgagttg ttgctgctgc agtgaaggct gcttggaatt cttcaaatga
     2221 accaaatgtt gcatcgattg ctgctgccag ttctgctgaa ggagctgttt tctcgggagt
     2281 catcaattcc cagaaaagag cgtggttcaa gtgtccgcca ccattgttga taagtgcttg
     2341 acggatatca gctgggatag attctacatc agcaagcaag gcttcaaggt cttcaccgat
     2401 ttcagggtgt ttttctaaag ctgcattggc attgttgaca taagtttgat ggtgtttgtc
     2461 atggtgcaaa tgcattgttt ccgcatcgat gtatggttcc aaagcgtcgt atgcatatgg
     2521 aagttctggt aagataatag ccatctgtaa tacctctttt tctttctata tgaaaatgat
     2581 aacgcaaaca ttcacttttt tcaagttttt tgcttataga taaggaaatc actgacatac
     2641 tttctaataa aataagcaaa tcagcaagaa acccacgaca agataatcct gacgcgggtt
     2701 gtagtttcaa caaatgtcaa ttgacctgac tagcaatctg taagagtgcc ttttcaaaaa
     2761 ggaaaccttt ttcataaaga cctgtcttaa tctgatagtc tgtctcaatc aaataggaaa
     2821 tagcttgctt cagaaagctc aaagaaagtc ctctcgaatc tcttaatgca aacttgattt
     2881 gataaggatt tgggttacgt cccagataac tacctaaact acttgcaatc tgcgattctg
     2941 tttggccaga ctccgccaaa atcttcacct gagtaaaagt ccgaaattgt cccagcatga
     3001 ctgcaatcag tttgatttca tcttcccctt gcaaggtcaa gtctctcacc aaatcgcgcg
     3061 cctgatccat ctttttagtc agaataaact gagttaaatc aaaaatattg tcctgcaagg
     3121 tcttgggaat tgcgttaaca atatcctctt cctcgataac agaatccgcc ttataggact
     3181 gtaaaaagag aagatttttc tggatttcgc taaattgaaa ccccgacttg atgaggagat
     3241 tttcaaaaga atgattggta aactgcagac cttgtttctg actccacttt tggaaatact
     3301 ggcgcaattc ttgttctttt acttctactg catcgaagac cttggcatca cgcttaagta
     3361 atttgactaa ccgtcttttg ctatccagct ttccttctgc aaagattatc aacttggttg
     3421 ttggagaagg attgtcaagg tattcctcaa atgacttaag ctcatcatct gtcaaaaagc
     3481 gtttcttagc agtcgtgata tccataaaat aatctaatat cacgattttc tcatccgcaa
     3541 agaaaggaag gctgaccaac tccagttcca catccttgta aactacttct ttcatatcaa
     3601 agtaggcaaa gttgaggtca gcagaatcat acccaatctg tttcaacact tgactcttca
     3661 tcacttcaaa ctgaccctga tctgtccctg taaataggct caggctcggt aaatttgata
     3721 aagtcaactt ctgactttct tcaatggcta gcatcgtctc tcctttcttc agatttttcg
     3781 atttaattta gtcaatatag cgcaatttcc cacggaaatc ttctaagctc tcgtagcctt
     3841 tttccaccat gattgctttc agttcattgg taatgcggtc aaaagcactg acgccttctt
     3901 tgtgaagggt cgttcccacc tgcaccatac ttgctccaca gaggatgtgt tcaaaggcat
     3961 ctcgaccagt cagaacgcca cctgttccga taatttggat ttgaggattt aaacgttgat
     4021 aaaaggcgtg aacattggct agagcagtcg gtttgatgta ttctccacca attccaccaa
     4081 aaccattctt aggccgaata acgacagatt cgtcttctat atagaggccg tttccgatag
     4141 agttaacgca gttgacaaac ttgagcggat atttgttgaa aatagctgcc gcttgatcaa
     4201 agtgaacaat atcaaaataa ggtggcaatt taattccaag aggtttggtg aagtaagcaa
     4261 acacttctgc caaaatccgg tctgttgtct caaaatcata ggcaatctga ggtttacctg
     4321 gaacatttgg acaggaaaga tttagctcag tcagaccacg aaaatcactc tcttggactt
     4381 ttttcaaaat agtatgggtt tcctctggag acatgccgac cagagataag aagaaagttc
     4441 ggttcgactc tttttcctgc aaatctaaaa gataatccaa ataatagtct aagccattat
     4501 ttggcaagcc catagagttg atggaaccaa gtggaacatc ttggtagcgt ggctcaggat
     4561 tcccctgacg gaagtccaag gtcgctgtct tagtaacaaa ggttcctgcc gctgagtttt
     4621 tgacctcttc taactcctct atcgtcatac aagccacacc tgctgcattc atcaagcaat
     4681 tgtcaaactc aaaaccagca atttgtgttt tcgttgatac catgattcta atcctccaga
     4741 tttcttttat tgctaatatt ataccataat tttaattcta ggtttactag attctgtggt
     4801 tctatctatt tattcggaaa agaaagtcta gtacagaagt catgctatgg aaacagctag
     4861 tgtattagaa gtttgaacaa ggcttgggta acagactttt gaatgaagtc caagcaacaa
     4921 ggagaaatct caaccatgag tccattccat gactctgttg ctctagaaaa ccttgcaata
     4981 gtcaagtgat aacgaataaa actttggatt gaaatatccc caagattatc tattacgagg
     5041 agaaatctta acctttatca tttttaaaga aatatagtaa aatgaaacaa gaacaggaga
     5101 aatcgatcag gacagtcaaa ttgattgcta acaatgtttt agaagttgag gtgtactatt
     5161 ctagtttcaa tctactatac atgtaaatct ctactttcgc aaaatggatt ttcagaacag
     5221 tatcccagta tagttaaaaa ctataaaaaa gagaggacgt tcccctctta aaatcttatt
     5281 ttactgcttc tttcaaagca tctaccttat ccaaacgttc ccatggaaga tcaatatctg
     5341 tacgtcccat gtgaccgtaa gccgatgttt gacggtaaat tggacgcttg aggtccagca
     5401 tttggataat ccctgcaggg cgaaggtcaa agatttgacg agccgctttt tcaagttgac
     5461 tttcagctac tgttcctgta ccgaaagtat cgatacgaac agaaacaggt tgcgcaacac
     5521 cgatagcata ggccaactgc acttctgcct tcttagcaag gcctgctgca acgatattct
     5581 tggcaatata gcgagccgca taagaggctg aacgatccac cttagtcgca tctttaccag
     5641 agaaggcacc accaccatga cgagagtagc caccataagt atctacaata atcttacgac
     5701 cagtcaaacc tgagtcccct tgaggaccac cgattacaaa acgacctgtc ggattgataa
     5761 agaattttgt cttatcatca agataagaag atggaataac ttctttgatg accttgtcaa
     5821 tcacatcttg atggatttgt tcattagtgg cctctggatc atgctgagta gaaataacga
     5881 ctgtatctac acgtaccgga cggtcatttt catcgtactc aactgtaact tgtgattttg
     5941 catctggacg gagatagcta atttctccag acttacgaag ttctgccaga cgacgaacca
     6001 atttatgact gagtgcaatt ggcaatggca taagctcttc tgtttcatct actgcaaatc
     6061 caaacatgag cccttggtca cctgctccaa tcaagtccag tggatcttga tcagcatttc
     6121 cacgaacctc caaggcttcg ttaacacctt gagcgatgtc aggagattgt tccaccaaag
     6181 atgggtgtac tcccaccgtc tcagcagaaa atccatattc tgtattggta taaccaatct
     6241 ctgcaatggt atcacgaacc acacggttaa tatccacata ggcatttgta gaaatttcac
     6301 caaaaacgtg gacagaacca gtatatacag ctgtttcagc agcaacgtgc gcctctggat
     6361 cctttgctaa aatagcatcc aaaatcgcat ctgaaatttg gtctgcaatc ttatccggat
     6421 gcccctcaga tacagattca gacgtgaata atttacgttc tgacataaaa atgtcccccc
     6481 ttaaaaaata ttgttataga gttacaaagt actgatagga aaactcttcg taataaatac
     6541 ctaccatctt atcgggacta tataacttta tcattatacc atttttaatc gcaatttgca
     6601 gtctttaatg tagtgtttcg gtttagatag ttcgttctca taaagcaaaa agttggagct
     6661 cagtactcca acaatttcta ttaaaatgtt tgacgtttag ctttacgctc tgcacgaccg
     6721 cgagcgcgat tttcagcacg cttggtttta cggcgctttt catcaaccgc ccattgaatt
     6781 ttcttcttat aacccggttt gacttttttc tttttctttt taaccaaacc aatcatttcg
     6841 atatcaagtt tatcttgttt tttctcacgg ttggcacgac gatcacggtc ataggtatct
     6901 tgaaattccc cgtctttgac catcttagga ctaaacttga ttcccaattt ctccaactca
     6961 cggatatccg agtcatcact tggctgataa agggtaatag ctgtacctgg taggccattt
     7021 cgtccagtac gaccaacacg gtgaacaaaa aaagataagt cttgcggaat ggcatcattg
     7081 atgacatggc tgacaccttc aatgtcaatc ccacgtgctg ccaaatctgt tgcgacaata
     7141 tactcaaaat ccagattttg cacctgattc atgattcgct tgcgttcacg aggggcaata
     7201 tcgccatgga tttttgcaac cttcaagcct tgagcagtca gatatgaatg caattcatca
     7261 gcacgcgttt tagtgttaac aaaaatcatt gccaaatacg gctgcatcaa ctgagtcaac
     7321 tggtaaattt gagcattctt atcatgtccc ttggtcgaaa tcaaccaatt atcaatggtg
     7381 tcagaaataa ccgttttggt cttaattttc tccataacag gattggataa gtattttttc
     7441 aagaatggtt gcagtttttg tgggatagtc gctgagaaga ccatgaattg caagtctttt
     7501 ggaagactgc cagcaatctt atcaacagtt tccaagaatc ccatatccaa ggtcatatcc
     7561 gcttcatcaa caacaaatgt cttggcttta tgaatagcta aatcaccaga tttaaccaag
     7621 tcgtagatac ggcctggtgt tccaataaca atatgaggct gattgcttgc caatttctca
     7681 atctggcgag ccttatccgt accacccaca taattaacca cacgaacttc gacatctgag
     7741 tgagctgaaa tctgacgcgc tacttggtaa atttgagtag ccaactcacg actcggtgca
     7801 gtaatcactg cttgtacact atcgctagct tcatctaatt gctggaaaat cggtaacaag
     7861 aaagtatgag tcttacctga acctgttttt gattctccta ctaggtcacg acctgccaaa
     7921 acaataggaa tcaacttatc ttgcacctct gttggagttg taaattttaa ctcctccaag
     7981 gcttctctaa tatagttttt aaattgaaat ttcgtaaatg acataacatc ctcgattcta
     8041 tctatcttat caattatacc atattttatt ccattacagt agtctcactt atttaggcta
     8101 tttccagtag cttctctagt aagaaaaggc tggaatttta taccccaatt attcacccc
//
LOCUS       DAVHKZ010000066         7902 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000066 DAVHKZ010000000
VERSION     DAVHKZ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7902
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.066"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            165..2798
                     /gene="polA"
                     /locus_tag="VVO74_002096"
     CDS             165..2798
                     /gene="polA"
                     /locus_tag="VVO74_002096"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU5696060.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNMSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDQLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEIKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            2883..3320
                     /locus_tag="VVO74_002097"
     CDS             2883..3320
                     /locus_tag="VVO74_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU5696061.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(3505..4515)
                     /locus_tag="VVO74_002098"
     CDS             complement(3505..4515)
                     /locus_tag="VVO74_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEU5696062.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVINAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            4664..5833
                     /locus_tag="VVO74_002099"
     CDS             4664..5833
                     /locus_tag="VVO74_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU5696063.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLKDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            5830..6600
                     /gene="recO"
                     /locus_tag="VVO74_002100"
     CDS             5830..6600
                     /gene="recO"
                     /locus_tag="VVO74_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU5696064.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            6597..7589
                     /gene="plsX"
                     /locus_tag="VVO74_002101"
     CDS             6597..7589
                     /gene="plsX"
                     /locus_tag="VVO74_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU5696065.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIVGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            7595..7828
                     /locus_tag="VVO74_002102"
     CDS             7595..7828
                     /locus_tag="VVO74_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU5696066.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
BASE COUNT         2238 a         1451 c         2017 g         2196 t
ORIGIN      
        1 caaggtgtac tattatagat tcaatatact atattatagc acatttttaa atctaggttt
       61 actaaattct ctggctctat ctatttattc ggaaaaagtt tgaaaaatac ttgctctagc
      121 tcttcccaat ggtatttttt gattctttcc tttataatgg gtgtatggat aagaaaaaat
      181 tattattgat tgatgggtct tctgtagctt ttcgggcgtt ttttgcgctg tatcagcagt
      241 tggaccgttt taagaatgcg gctggtttgc ataccaatgc gatttatggt tttcagttga
      301 tgttgagtca tttgttggag cgggttgagc cgagtcatat tttggtggct tttgatgcgg
      361 gaaagacgac cttccggaca gagatgtatg cggactataa gggtggtcgg gccaagactc
      421 ctgatgagtt tcgtgagcaa tttcctttca ttcgtgagtt gctggatcat atggggattc
      481 gtcactatga gctggctcag tatgaggcgg atgacatcat tgggacgctg gataagctag
      541 cagagcagga tggttttgat attaccattg tcagtgggga caaggatttg attcagctga
      601 cggatgagca tacggtggtt gaaatttcca agaaaggtgt ggctgagttt gaggccttta
      661 cgccagatta cctcatggaa gaaatgggcc tcacaccagc tcagtttatc gatctcaagg
      721 cgctcatggg tgataagtcg gataatatcc ctggggtgac caaagtcggt gaaaagacgg
      781 gtattaagct cttgctggag catggttcgc ttgaggggat ttatgaaaat attgatggaa
      841 tgaagacttc taagatgaag gaaaatctca tcaatgacaa ggaacaggcc tttttgtcta
      901 aaacactagc gaccattgat accaaggcac cgattgcgat tggtttagag gacttggtct
      961 atagtggtcc agatgttgaa aatcttggga aattctacga tgagatgggc ttcaaacagc
     1021 tcaagcaggc tttaaatatg tcgtcagctg atgtggctga gggtttggat tttactattg
     1081 ttgaccaaat cagtcaagat atgctgagtg aagagtctat cttccacttt gagctttttg
     1141 gtgagaatta ccatacagat aatttggttg gatttgcctg gtcttgtggg gatcagctct
     1201 atgccacaga caagcttgag ctgttgcaag acccgatttt caaggatttc ttagaaaaaa
     1261 catctctgag agtttatgac tttaagaagg ttaaagttct tttgcaacgt tttggtgtag
     1321 atttgcaggc gcctgctttt gacatccgtt tggctaaata cctcctttcg actgtggagg
     1381 acaatgaaat tgcgaccatc gctagtcttt atggtcagac ttacttggtt gatgatgaaa
     1441 ctttctacgg taagggtgtt aaaaaggcca ttcctgaacg tgagaaattc ttggaacact
     1501 tagcttgtaa acttgctgtt ttggtagaaa cagagcctat tttacttgaa aaacttagcg
     1561 aaaatgggca attagagctt ctttatgata tggagcaacc tctggctttt gtccttgcca
     1621 agatggaaat tgctgggatt gtggtcaaga aagagacctt gcttgagatg caggctgaaa
     1681 atgagcttgt cattgaaaaa ctgactcaag agatttacga gctggctggt gaggagttta
     1741 atgtcaactc gcctaagcag ttgggcgtgc ttctctttga gaaattggga cttcctctag
     1801 aatacactaa gaaaaccaag acaggttatt cgacagcagt ggatgtgttg gagcgtctcg
     1861 ctcctattgc tccgattgtt aagaaaatcc tggattaccg tcaaattgct aagattcaat
     1921 ctacttatgt aattggcttg caggactgga ttttggctga tggaaagatt catactcgct
     1981 atatgcagga tttgacccag accgggcgtt tgtctagtgt ggatccaaac ttgcaaaata
     2041 ttcctgcccg attggaacaa gggcgcttga ttcggaaggc ttttgtgcca gagtgggagg
     2101 atagtgtgct actcagctct gactattcac agattgaatt gcgcgttttg gcgcatattt
     2161 ctaaggatga gcacttgatt aaggccttcc aagagggggc agatatccat acttcgacag
     2221 ccatgcgggt ctttggcatt gagcgtcctg ataatgtgac tgcaaatgac cgtcgcaatg
     2281 ccaaggcagt taactttgga gtggtttatg ggatttcaga ctttggcttg tctaataatt
     2341 tgggaattag tcgtaaggaa gccaaagcct acattgatac ctactttgaa cgttttccag
     2401 gtattaaaaa ctacatggat gaagtggtgc gggaggcgcg tgataagggc tatgtagaga
     2461 ccctctttaa gcgtcgccgt gagttgccag atatcaattc gcgcaacttc aatattcgtg
     2521 gttttgcgga gcgaactgct atcaactcac ctatccaggg ttcggcagca gatattctca
     2581 agattgccat gattcagctg gataaagcct tggttgcagg tggttatcag actaagatgc
     2641 tgttacaagt gcacgatgaa atcgtccttg aagtgcctaa atctgaattg gtagagataa
     2701 aaaaattggt gaaacaaacc atggaagaag ccattcaact cagtgttcct cttatcgcag
     2761 atgagaatga aggggcaacc tggtacgagg ctaaataaaa agggggctag tcctcctttt
     2821 ttgtagtaga attctgcaaa ccttttcaaa atgtgctata ctgatgaaaa aggaggattt
     2881 ctatgagtca agaatttatc aatccaagtg atggcgtgat tcgtcagtat ctcgcaacga
     2941 gtaaaaccct tgctgtggtg ggtttgtctg accgtgaaga aacaaccagc aatcgagtaa
     3001 caaaggaaat gcaggctcgg ggctataaaa tcatcccagt caatcccaag gcggcaggtg
     3061 gcgaaatctt gggtgaaaag gcttatgcta gcctcgctga aattcctttt cctgtagata
     3121 ttgtcaatgt ttatcgtcgc agtgaatttc tgcccgatgt ggcgcgtgat tttctcaaag
     3181 ctgatgccaa gattttttgg gcacagctag gacttgaaag tttagaagca aaagagattt
     3241 tgcgtgatgg tggatgtgat gatatcgtga tgaatcgctg tatcaagaga gaacatactc
     3301 gcttgattga ggaagcataa gaaaaaggta gctgatgggc taccttttgt gttatactca
     3361 atgaaaatca aagagcaaac taggaaacta gctgcgggtt gctcaaaaca ccgttttgag
     3421 gttgcagata gaactgacga agtcagtaac atatacctac ggcaaggcga cgttgacgtg
     3481 gtttgaagag attttcgaag agtgttagaa aatgccgata agggtctgca taccaagagt
     3541 ggtgaggatg atggcaatcc agcagatggc tccaagaaga atggattttc cactggattt
     3601 gaccatagcg accagattgg ttttgagacc gatagcactc atggccatga caataaggaa
     3661 tttagagagt tctttgagag gggtaaagaa actactggac acacctagag aggtgagtag
     3721 tgtagtgagg agagaggcaa ggataaagta aaggataaaa agtgggaaga cttttttcag
     3781 ttgtaggctt tgcttgtttt cttgttggcg actttgccag taggatagaa agagcgtgat
     3841 agggataatg gccaaagtac gtgtgagttt aacaatggtt gcagactcga gggtattgct
     3901 ttggtaaaga ctgtcccaag cgctggcggc agccgttaca gaggaagtgt cgttgaccgc
     3961 agtccctgca aagagggcga agccttcatt ggatagatga agccaggtgc cgagggttgg
     4021 aaagatgagc gcagccaaga cattgaagaa aaagataacg gaaatggctt gggctacttc
     4081 cttttcctta gcattaataa cgggcgctgt cgctgcaatg gcagaacccc cacagataga
     4141 agaacctact ccaaccaagg tagccagttt tgtatccagt gcaaagaaac gctggaagag
     4201 gtaggcaata atcagagcta ttgagatagt ggacaggatg acagggagtg aagattggcc
     4261 aactgcgaag acctgcgaga tattgagacc aaaaccaagc aagacaacgg catattggag
     4321 caacttcttg gaactaaagg tcaaaccagc atccagttgt ttataggacg agagaaaggg
     4381 atgtaggagc atgcctatga aaatggcaaa aacgggcgcg ccaatcacag ggaagaatcc
     4441 tcctaagtac caagatacga tagaaatgag aaggcaggcc aagatacctg ctccattttt
     4501 tgatagaaat gacataaaaa cctccaaata aaatctatta ccattataga cctataaaca
     4561 ggaaaagtaa aatagaaagt ggaaagctat tctctaatgt atttttgcgg tcgggaggct
     4621 tttgtagtat aatagagata cgttttgaaa gtaggaggta tctatggact taactaagcg
     4681 ctttaataaa cagttagata agattcaagt ttcgttgatt cgtcagtttg accaggctat
     4741 ttcggagatt cctggggtct tgcgtttgac cttgggggaa cctgatttta caacgccaga
     4801 ccatgtcaag gaggcggcca agcgagcgat tgatcagaac caatcctact atacagggat
     4861 gagtggtctg ctgactctac gtcaggcagc tagtgacttt gttaaggaaa agtaccaact
     4921 ggactatgct cctgaaaatg aaatcttggt tacaattggg gcgacagagg ctttatctgc
     4981 gactttgacg gctattttgg aagagggaga caaggtactt ttgccagctc ctgcttatcc
     5041 aggctatgaa ccgattgtta acttagttgg ggcagaaatt gttgagattg atacgactga
     5101 aaatggtttt gtcttgactc ctgagatgtt ggagaaggcc attttggagc agggtgataa
     5161 gctcaaagcg gttattctca actatccagc caatccgaca ggaattacct acagtcgaga
     5221 gcagttagag gccttggcag ctgttttacg caagtacgaa atttttgttg tctgtgatga
     5281 ggtttactca gaattgacct acacaggcga agcccatgtg tctctaggaa cgatgttgaa
     5341 agaccaggct attattatca atggtttgtc taaatcgcat gccatgacag gttggcgttt
     5401 ggggctgatt ttcgctcctg cggccttcac agcccagtta atcaagagtc accaatactt
     5461 ggtcactgcc gcaaatacca tggcgcaaca tgctgcggta gaagccttga cggctggtaa
     5521 aaatgatgcg gagcccatga agaaggaata tatccagcgt cgggactata tcatcgaaaa
     5581 aatgactgct cttggttttg agattatcaa accagacggt gccttctata tttttgctaa
     5641 aattccagcg ggctacaatc aagactcctt tgcttttctg aaggattttg ctcagaagaa
     5701 ggccgttgcc tttatccctg gtgcagcctt tggacgttac ggggaaggct acgtccgcct
     5761 atcttatgca gccagcatgg agactatcaa agaagccatg aaacgacttg aggagtacat
     5821 gagagaagca tgattcagtc tatcacgagt caaggcttgg tgctttacaa tcgcaatttt
     5881 cgtgaggatg acaagctcgt caaaattttt acagagcagg ttggcaaacg catgtttttt
     5941 gtcaaacacg ctggtcagtc taagctggcg cctgttattc agcccttggt gttggcacga
     6001 tttctcttgc gaatcaatga tgacggactc agttacatcg aagactatca tgaggtcatg
     6061 acttttccca agattaatag tgacctcttt gtcatggcct atgcgaccta tgtggcagct
     6121 cttgcagatg ctagtttgca ggacaatcag caggatgctc ccttgtttgc ttttttgcaa
     6181 aagactttgg agttgatgga agcaggcttg gattatcagg ttttgaccaa tatttttgaa
     6241 attcaaattt tgactcgatt tggaatcagc ctcaatttta atgagtgtgt cttctgccat
     6301 cgggttggtc aggcttttga cttttctttc aaatatggag cctgcctctg tccagagcat
     6361 tatcatgagg ataagagacg ttgtcatctc aatcccaata tcccctatct gctcaatcaa
     6421 tttcaagcta ttgattttga gactttggag accatttcgc tcaagcctgg aatcaagcaa
     6481 gagctacgcc aatttatgga tcaattatat gaagagtacg ttgggattca cctaaaatca
     6541 aagaaattta ttgattccct agcagactgg ggacaattac taaaagagga aaagaaatga
     6601 aaaaaatcgc agtagatgcc atggggggcg attacgcacc tcaggccatt gttgagggtg
     6661 tcaatcaagc cctatctgac ttttcagata tcgaggttca actttacgga gatgaagcta
     6721 aaatcaagca atatctgaca gcgacagagc gcgtcagcat tatccatacg gatgagaaga
     6781 ttgattcgga tgatgaacct acgagagcta ttaggaataa gaaaaatgcc agtatggtat
     6841 tggcagccaa ggctgtcaaa gatggtgaag cagacgctgt cctttcggct gggaatacag
     6901 gtgccttgtt ggcagcagga ttcttcatcg tgggtcgtat caagaatatc gaccgtcctg
     6961 gactcatgtc taccttgcct accgttgatg gaaaaggttt tgacatgcta gaccttggtg
     7021 ccaatgcaga aaatacagcc cagcacctcc atcaatatgc ggttctaggt tccttctatg
     7081 ctaaaaatgt ccgtggcatt gcgcaaccac gcgttggttt gctcaacaac ggaacagaga
     7141 gtagcaaggg cgacccgctt cgtaaggaaa cttatgaatt actggcggct gatgaaagtt
     7201 tgaactttat cggaaacgtg gaagcgcgtg atttgatgaa tggcgttgca gatgttgttg
     7261 tggcagatgg tttcacggga aacgctgtgc tcaaatccat cgaagggaca gctatgggaa
     7321 tcgtgggctt gctcaagaca gctattacag gtggtggtct tcgagcgaaa ctaggtgccc
     7381 tccttctcaa ggacagcctc agtggtttga aaaaacagct caattattca gatgttggtg
     7441 gagcggtctt gtttggtgtt aaggcacctg ttgtcaagac tcatggctca agcgatgcca
     7501 aggctgttta tagtacgatt cgtcagattc gtaccatgct agaaacagac gtggttgccc
     7561 agactgcgcg tgaattttca ggagaataaa agagatgaca gaaaaagaaa tttttgaccg
     7621 tattgtgacc attatccaag agcgacaggg agaggacttt gtcgtgacag aatccttgag
     7681 tctgaaagac gatttggatg cggattctgt tgacttgatg gagtttatct tgactctgga
     7741 agatgaattt agtatcgaaa tcagcgatga ggaaattgac caactccaaa gtgtaggaga
     7801 tgtggttaaa atcattcaag gaaaatagca atcggagttc caagtcaacg gaagtagatg
     7861 gtttttagaa atgagaaata ttggacaagc tggtaaaatc tt
//
LOCUS       DAVHKZ010000067         7100 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000067 DAVHKZ010000000
VERSION     DAVHKZ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7100
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.067"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            1..404
                     /locus_tag="VVO74_002103"
                     /pseudo
     CDS             1..404
                     /locus_tag="VVO74_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            571..771
                     /locus_tag="VVO74_002104"
     CDS             571..771
                     /locus_tag="VVO74_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696067.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            813..1217
                     /locus_tag="VVO74_002105"
     CDS             813..1217
                     /locus_tag="VVO74_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696068.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1448..2155
                     /gene="ccdA2"
                     /locus_tag="VVO74_002106"
     CDS             1448..2155
                     /gene="ccdA2"
                     /locus_tag="VVO74_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU5696069.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDFNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2166..2723
                     /gene="sdbB"
                     /locus_tag="VVO74_002107"
     CDS             2166..2723
                     /gene="sdbB"
                     /locus_tag="VVO74_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU5696070.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            3097..4488
                     /locus_tag="VVO74_002108"
     CDS             3097..4488
                     /locus_tag="VVO74_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU5696071.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4631..5548
                     /gene="adcAII"
                     /locus_tag="VVO74_002109"
     CDS             4631..5548
                     /gene="adcAII"
                     /locus_tag="VVO74_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU5696072.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLAEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5556..>7100
                     /gene="phtB"
                     /locus_tag="VVO74_002110"
     CDS             5556..>7100
                     /gene="phtB"
                     /locus_tag="VVO74_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEU5696073.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVLKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAQAYWNGKQGSRPSSSSSYNANTAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFY
                     NKAYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDISSDKVKLVEDILAFLAPIRHP
                     ERLGKPN"
BASE COUNT         2186 a         1307 c         1495 g         2112 t
ORIGIN      
        1 tagcttctga atttggctgt catccaacta ccatccacta tgcgttcaaa gctatgggct
       61 acactcgaaa aaaagaacca cacctactat gaacaagacc cagaaaagta gccttatttc
      121 ttaagaattt taatagttta aagcacctag cacctgttta gattgatgaa acaggattcg
      181 atacttattt ttatcgagaa tatggtcgct cattaaaagg tcagttaaga agaggcaaag
      241 tatctggaag aagatatcag aggatttctt tggttgcagg tctaacaaat ggtgaattaa
      301 tcgctccaat gacttacgaa gagatgatga cgagcgactt ttttgaagta tggtttcaga
      361 agtttttctt accaacatta accacaccat cggttattat agtaaaatga aataagaata
      421 ggacaaatcg atcaggacag taaaatcgaa ttctaacaat gttttagaag tccatatgta
      481 ctattctagt ttcaatatac cataactgtt cctagtcaac ctgcaagccc tgtcccagct
      541 ccaagctcag ctccgactca agatcctaga gtggtagcaa gcgcttcggc tagctcaacg
      601 agcacacaag ctcaagagca agttgacaag tctgaacttc gtgccttgag tcaagagtta
      661 gaccaacgct tgaaagcttt ggcaacagta tctgatccga aaatcgatgc aaccaaggct
      721 gtcctcctag atgctcaaaa agctccggaa gatagtgcct tgacagagta aggtctgcat
      781 actgcagtag agtctgtgaa ggctgggctg ccttggactc tctcaaagat gtgaaagcaa
      841 atgctagcga cagcaagcct gcacaggaca agaaggatgc aaaacaagga acggaagata
      901 gtaaggattc agataagatg actgaaacaa actcagttcc ggcaggagtg attgtggtca
      961 gtctacttgc cctcctaggc gtgattgcct tctggctgat tcgccgtaag aaagagtcag
     1021 aaatccagca attaagcacg gaattgatca aggttctagg acagctagat gcagaaaaag
     1081 cggataaaaa agtccttgcc aaagcccaaa accttctcca agaaaccctt gatttcgtga
     1141 aagaagaaaa tggctcagca gagacagaaa ctaaactagt agaggagctt aaagcaatcc
     1201 ttgacaaact caagtaaaac atgatttatg aaatgttaga cctaaaagac attttcgttc
     1261 acaaaagcag cgatgagtaa tccttgtcgt tgctttttgg ctattttggg ggataagatc
     1321 cgccttgact agcaaaagaa aagattggtc caatagtgcc cgatacgatt ttgcgtagca
     1381 gaaagcttac aaataaaatt gaatatagta aaataggatt agaattatta agaaagttgg
     1441 ttctttattg gaaacgatag tatttttaat ctctgttttt ctagcaggtg ttttatcctt
     1501 tttttctcct tgtatttttc ctcttctgcc agtctatgct gggattttat tggatgatca
     1561 agaaagtgca aaaagctttt ctttgtttgg gagaaaggtt ctctggtcag gcttgattcg
     1621 aacactttgc tttatcgctg gtatctctct cattttcttt attctaggct ttggtgctgg
     1681 ttactttggt catattctct atgcaaattg gtttcgatat gtcatgggag ctattattat
     1741 cattttgggt cttcaccaga tggaaatttt tcatttgaag aaattagaag ttcaaaaaag
     1801 ttttaccttt aaaaaatcag attttaatcg ttattggtca gcttttttac ttggtattac
     1861 ctttagcttt ggttggacac cttgtattgg tccagtttta agttctgttt tagcacttgc
     1921 ggcttctgga ggcaatggtg cttggcaagg agcgatttat actctcattt acactctggg
     1981 catggccctt cctttcttgg tcttggcact agcttcaggt ctagtcatgc catattttag
     2041 taaaatcaag cgtcatatga tgctactaaa gaaaattggt ggtttcctca ttgttttaat
     2101 gggaattttg ttactattag gacaagtaaa tgttctagct ggaatttttg aataaaggag
     2161 gacaaatgaa aaaagtaatg tttgctggct taagtctctt gtcattagtt gtattgatgg
     2221 cctgtggtga ggaagaaact aaaaagactc aagcagcaca acagccaaaa caacaaacga
     2281 ctgtacaaca aatttctgtt ggaaaagatg ctccagactt tacattgcaa tccatggatg
     2341 gcaaagaagt taagttatct gattttaagg gtaaaaaggt ttacttgaag ttttgggctt
     2401 catggtgtgg tccatgcaag aaaagtatgc cagagttgat ggaactagcg gcgaaaccag
     2461 atcgtgattt cgaaattctt actgtcattg caccaggaat tcaaggtgaa aaaactgttg
     2521 agcaattccc acaatggttc caggaacaag gatataagga tatcccagtt ctttatgata
     2581 ccaaagcaac caccttccaa gcttatcaaa ttcgaagcat tcctacagaa tatttaattg
     2641 atagccaagg aaagattgga aagattcaat ttggtgctat cagtaatgcg gatgcagaag
     2701 cagcatttaa agaaatgaac tagaatcgat aaaatctgat tacaagatgt agtcagattt
     2761 tggtaacttc taaaactaac ttccagtttc ccacaaccta gcttttagta tgagaaaaac
     2821 gcgtgacatc agtggaaatc cgtcttagac taacttccac tggttttctt tttcttgata
     2881 tataagggtt caaaagcgaa aagactcaga aaaagtgcac gacaaatagc cctaaaacag
     2941 agtcgtctta gagtaacttc cagttttggg agagagatgg aagttacttt gagaagttac
     3001 ggtagtcaga tttttttaga aaaacatttt ataaatattc acatatctcc tatatttatg
     3061 gtaaaataga attatcagtt tattttggag tcaaagatga atatatttag aacaaagaat
     3121 gttagtttag ataaaacaga gatgcatagg catttgaagt tatgggattt gattttgctg
     3181 ggtatcggag ccatggtagg gacaggcgtc tttacaatca caggtactgc agctgcaaca
     3241 cttgctggcc cagccctagt gatttcaatc gttatttctg ccttgtgtgt gggattatca
     3301 gccctctttt ttgcagaatt tgcctcgcga gtacccgcta caggaggtgc ctatagttac
     3361 ctctatgcta tcttaggaga attccctgcc tggttggctg gttggttaac catgatggag
     3421 ttcatgacag ccatatcagg cgtagcttcg ggttgggcag cttattttaa aggcttgctc
     3481 tctcaatacg ggatagcctt tcctcaggct ttaaatggta cctttaatcc tcaagcaggg
     3541 acatttgttg atttattgcc tattcttgtc ttggtcttgg tgacttcgct tgttttacta
     3601 aatgccaagg cagccttacg ctttaattcg attctagtta ttttgaaatt ttccgcttta
     3661 gctctctttg ttttagtagg aatttggaat attaagtttg ataattggag caattttgct
     3721 ccttacggtt ttggacaaat ctatggagct agtactggta ttatggctgg tgcatccttg
     3781 atgttcttcg gttttttggg atttgaatcc atctctatgg ctgtagatga agtcaagact
     3841 cctcaaaaaa atattcctag agggattgtc ttatcgcttt ctatcgtaac cattctctat
     3901 gccttggtga cccttgtttt gactggtgtg gttcactata gtcatttaaa tgtcgatgat
     3961 gccgttgcct ttgcccttcg tagtgttggg attagttggg cagccaacta tgtgtcatta
     4021 gtggctatct tgaccttgat tacagtttgt atttcgatga cctatgccct atcgcgtatg
     4081 atttacagtt tagcacgtga cggcttagtg cctgctgcct ttaaggaact gacgaagact
     4141 agcaaggtac caaagaatgc tactatcttg acaggtctag cttcagcagt agcagcagga
     4201 atgttcccac tagccagtat tgcagccttt ttaaatattt gtaccttagc ctacttgatc
     4261 atgttggctt atggtctgat tcgcttacgg aaagaaaaag gaatgcccaa agctggggaa
     4321 tttaaaacac cattggtacc tctgttacca attttatcga tcatcatttg tttatccttc
     4381 atgttacagt ataatatgaa tacctggatt gctttcctag ttgcgttgtt agtaggaagt
     4441 attatttact tcacttatgg ctataagcat tctaccatag aagaataaag tgaaagtcta
     4501 ttgagttgtt gacactcagc agatttttat atgtgaaaga aatttcaaat tttttctaaa
     4561 aatatcttga cagattaaat tttcaggagt agaatattta ctagttaatt aaatggttaa
     4621 ggagttgttc atgaagaaac aaaatttatt tttagtcctg ttaagtgtct ttcttttgtg
     4681 cttgggggct tgtggtcaaa aggaaagtca gacaggaaag gggatgaaaa ttgtgaccag
     4741 tttttatcct atctacgcta tggttaagga agtatctggt gacttgaatg atgttcggat
     4801 gattcagtca agtagtggta ttcactcctt tgaaccttcg gcaaatgata tcgcagccat
     4861 ctatgatgca gatgtctttg tttaccattc tcatacactc gaatcttggg caggaagtct
     4921 ggatcccaat ctaaaaaaat ccaaagtgaa ggtcttagag gcttctgagg gaatgacctt
     4981 ggaacgtgtc cctggactag aggatgtgga agcaggggat ggagttgatg aaaaaacgct
     5041 ctatgaccct cacacatggc tagatcctga aaaagctgga gaagaagccc aaattatcgc
     5101 tgataaactt tcagaggtgg atagtgagca taaagagact tatcaaaaaa atgcgcaagc
     5161 ctttatcaaa aaagctcagg aattgactaa gaaattccaa ccaaaatttg aaaaagcgac
     5221 tcagaaaaca tttgtaacac aacatacagc cttttcttat ctagcgaaga gatttgggct
     5281 taatcaactt ggtattgcag gcatctctcc tgaacaagaa ccaagtccac gacaattagc
     5341 agaaattcag gaatttgtta aaacctataa ggttaaaacg atttttacag aaagtaatgc
     5401 ttcttcaaaa gtagctgaaa ctcttgtcaa atcaacaggt gtgggtctta aaactctgaa
     5461 tcctttagag gcagacccac aaaatgacaa gacctattta gaaaatctgg aagaaaatat
     5521 gagtgttcta gcagaagaat taaagtgagg aaagaatgaa aatcaataaa aaatatctag
     5581 caggttcggt ggcagttctt gccctaagtg tttgttccta tgagcttgga cgttaccaag
     5641 ctggtcagga taagaaagag tctaatcgag ttgcttatat agatggtgat caggctggtc
     5701 aaaaggcaga aaacttgaca ccagatgaag tcagtaagag ggaggggatc aacgccgaac
     5761 aaatcgtcat caagattacg gatcaaggtt atgtgacctc tcatggagac cattatcatt
     5821 actataatgg caaggtccct tatgatgcca tcatcagtga agagctcctc atgaaagatc
     5881 cgaattatca gttgaaggat tcagacattg tcaatgaaat caagggtggt tatgtcctta
     5941 aggtaaacgg taaatactat gtttacctta aggatgcagc tcatgcggat aatattcgga
     6001 caaaagaaga gattaaacgt cagaagcagg aacgcagtca taatcataac tcaagagcag
     6061 ataatgctgt tgctgcagcc agagcccaag gacgttatac aacggatgat gggtatatct
     6121 tcaatgcatc tgatatcatt gaagatacgg gcgatgccta tatcgttcct cacggcgacc
     6181 attaccatta cattcctaag aatgagttat cagctagcga gttagctgct gcccaagcct
     6241 attggaatgg gaagcaggga tctcgtcctt cttcaagttc tagttataat gcaaatacag
     6301 ctcaaccaag attgtcagag aaccacaatc tgactgtcac tccaacttat catcaaaatc
     6361 aaggggaaaa catttcaagc cttttacgtg aattgtatgc taaaccctta tcagaacgcc
     6421 atgtggaatc tgatggcctt attttcgacc cagcgcaaat cacaagtcga accgccagag
     6481 gtgtagctgt ccctcatggt aaccattacc actttatccc ttatgaacaa atgtctgaat
     6541 tggaaaaacg aattgctcgt attattcccc ttcgttatcg ttcaaaccat tgggtaccag
     6601 attcaagacc agaacaacca agtccacaat cgactccgga acctagtcca agtctgcaac
     6661 ctgcaccaaa tcctcaacca gctccaagca atccaattga tgagaaattg gtcaaagaag
     6721 ctgttcgaaa agtaggcgat ggttatgtct ttgaggagaa tggagtttct cgttatatcc
     6781 cagccaagga tctttcagca gaaacagcag caggcattga tagcaaactg gccaagcagg
     6841 aaagtttatc tcataagcta ggagctaaga aaactgacct cccatctagt gatagagaat
     6901 tttacaataa ggcttatgac ttactagcaa gaattcacca agatttactt gataataaag
     6961 gtcgacaagt tgattttgag gctttggata acctgttgga acgactcaag gatatctcaa
     7021 gtgataaagt caagttagtg gaagatattc ttgccttctt agctccgatt cgtcatccag
     7081 aacgtttagg aaaaccaaat
//
LOCUS       DAVHKZ010000068         6976 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000068 DAVHKZ010000000
VERSION     DAVHKZ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6976
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.068"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            1..567
                     /locus_tag="VVO74_002111"
                     /pseudo
     CDS             1..567
                     /locus_tag="VVO74_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            628..1590
                     /locus_tag="VVO74_002112"
     CDS             628..1590
                     /locus_tag="VVO74_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU5696074.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYEDTSISVSSNETDKV
                     LAGSLYTDTNEQGLMIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAEASKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1767..2774
                     /gene="gap"
                     /locus_tag="VVO74_002113"
     CDS             1767..2774
                     /gene="gap"
                     /locus_tag="VVO74_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU5696075.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2842..3678)
                     /locus_tag="VVO74_002114"
     CDS             complement(2842..3678)
                     /locus_tag="VVO74_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU5696076.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVRWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3804..5999
                     /locus_tag="VVO74_002115"
     CDS             3804..5999
                     /locus_tag="VVO74_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU5696077.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            6052..6204
                     /gene="rpmG"
                     /locus_tag="VVO74_002116"
     CDS             6052..6204
                     /gene="rpmG"
                     /locus_tag="VVO74_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU5696078.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6214..6390
                     /gene="secE"
                     /locus_tag="VVO74_002117"
     CDS             6214..6390
                     /gene="secE"
                     /locus_tag="VVO74_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU5696079.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6445..>6976
                     /gene="nusG"
                     /locus_tag="VVO74_002118"
     CDS             6445..>6976
                     /gene="nusG"
                     /locus_tag="VVO74_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU5696080.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT         2177 a         1228 c         1503 g         2068 t
ORIGIN      
        1 cgctcaaagc tatgggctac actcgaaaaa aagaaccaca cctactatga acaagaccca
       61 gaaaaagtag ccatatttct taagaatttt aatagattaa agcacctagc acctgtttag
      121 attgacgaaa caggattcga tacttatttt tatcgagaat atggtcgctc attaaaaggt
      181 cagttaataa gaggcaaagt atctggaaga agatatcaga ggatttcttt ggttgcaggt
      241 ctaacaaatg gtgaattaat cgctccaatg acttacgaag agacgatgac gagcgacttt
      301 tttgaagctt ggtttcagaa ttttctctta ccaacattaa ccacaccatc ggttattatt
      361 atggataatg taagattcca tagaatgggg aagctagaac ttttatgcga agagtttggg
      421 cataaactgt tacctcttcc tccctactcg cctgagtaca atcctattga gaaaacatgg
      481 gctcatatca aaaagcacct caaaaaggta ttaccaagtt gcaatacctt ttacgaggct
      541 cttttgtctt gttcttgttt caattgacta tagttcacgg atacagttgg gaaagaagct
      601 attaattatt tggagagtcc ttttgggatg aacatgtcaa atattactat agatgggcaa
      661 gaaatggatc tgagtcaaac gatgccttct tatgctcaag tagtgagtct ttatgaggat
      721 acaagcatct ctgttagtag taatgagacg gacaaagtgt tggctggatc cctctatact
      781 gatacaaatg aacagggatt aatgattcca agcagtttac taaaaaattg gaatgaacag
      841 acaggaaaaa atttgacagc taatgatctt attggcaaat cagtctcagc cagcattgta
      901 gaaagtgctg ccgaagctag taagattgct caatttcaaa cgaagattgt acgtgtaatc
      961 aatgatgaag atgacatgga ggacagcaac agtttcatgc tgtctcatca aatggaaacg
     1021 attttgaaag aggctggatt tacgaaagct gtatcttatt ttatcttgga actcaaagat
     1081 ccatcacaga caaaagtagt aacagaagaa ttacagaaaa ataagaagta tactgtgctt
     1141 tctcaacaga gagttcttga tattgtgatt acctttattc gtgttattca gggattattg
     1201 attgtgcttt catcacaagc tattgtggta gcagcggtta tgattggtat cattatttac
     1261 atcaatatca tgcaacgttc caaggaaata ggtgtcatga aagcagttgg ttatcagaat
     1321 cgtggtgtca aaggaatttt tatttacgag gctatctgga ttgtaggcat cgccttgctg
     1381 ctggcatttt tggttgcaca aggggtggga agtttggcga atgcgattgt aagtcacttt
     1441 tacccatcca tcactaaggt ttttgaatta aatcttttat ctgttttagg aactctagtt
     1501 ttcgctctat tacttggtta tgtctcagcc tacttcccgg cgcgtaagat tagtaaaatg
     1561 gatcctgtag aatcgttacg ctatgaataa taagggattc cttgatttac agtcttaaaa
     1621 agaaactcac atagaaaaac aatggccata cttgcaattc aactcaaata gttgtataat
     1681 aggtttgttg aaaggtgatt tgtagtgatt caagttactc ttttcacaat aaaaatttca
     1741 tgattttcat aaggaggaaa tcactaatgg tagttaaagt tggtattaac ggtttcggac
     1801 gtatcggtcg tcttgctttc cgtcgtatcc aaaacgtaga aggtgttgaa gttacacgca
     1861 tcaacgacct tacagatcca gttatgcttg cacacttgtt gaaatacgac acaactcaag
     1921 gtcgtttcga cggtactgtt gaagttaaag aaggtggatt tgaagttaac ggtaaattca
     1981 tcaaagtttc tgctgaacgt gatccagaac aaatcgactg ggctactgac ggtgtagaaa
     2041 tcgttcttga agctactggt ttctttgcta agaaagaagc agctgaaaaa caccttaaag
     2101 gtggagctaa aaaagttgtt atcactgctc ctggtggaaa cgacgttaaa acagttgtat
     2161 tcaacactaa ccacgacgtt cttgacggta ctgaaacagt tatctcaggt gcttcatgta
     2221 ctacaaactg cttggctcca atggctaaag ctcttcaaga caactttggt gttgttgaag
     2281 gattgatgac tactatccac gcttacactg gtgaccaaat gatccttgac ggaccacacc
     2341 gtggtggtga ccttcgccgt gctcgcgctg gtgctgcaaa catcgttcct aactcaactg
     2401 gtgctgcaaa agctatcggt cttgtaatcc cagaattgaa tggtaaactt gatggatctg
     2461 cacaacgcgt tccaactcca actggatcag ttactgaatt ggtagcagtt cttgaaaaga
     2521 acgttactgt tgatgaagtg aacgcagcta tgaaagcagc ttcaaacgaa tcatacggtt
     2581 acacagaaga tccaatcgta tcttcagata tcgtaggtat gtcttacggt tcattatttg
     2641 acgcaactca aactaaagtt cttgacgttg acggtaaaca attggttaaa gttgtatcat
     2701 ggtacgacaa cgaaatgtca tacactgcac aacttgttcg tactcttgaa tacttcgcaa
     2761 agattgctaa ataattcttg agttgataga aagcaaggct ttgtggtctt gcttttttat
     2821 atggaaaaat ggatgacacg atcatccatt cttttttaat tctttttcaa atgtatttga
     2881 aagggtagtg aaagttagcc tctctaaagt aagtgggtgg gtaaaggaaa gtcggaaggc
     2941 atgaagcata agccggcttg tctttgattt actattatag agagggtctc ccaggatagg
     3001 aagattatga tgcaaaaggt gcacacgaat ctgatgggtt cgccctgtct ttagcttgca
     3061 atgagccaag gaagtcttgt ttgagaattg ctttaatctg cttacatgcg tttcagcata
     3121 ttgcccattt tttgcatcaa ctattctttt tctacgatca tggcgatcac gtccaatttt
     3181 gtctctgaaa acaagttctt ttctgttgat atttccatca actagagccc aatattctct
     3241 agaaatctct tttttctcca ataagcgatt gagaatgggc aggataaaag gatttttggc
     3301 aaagagaact aagccactgg tttccatgtc cagacgatga acgacatagc aggtttggcc
     3361 aacataggta ctgacatggt taagaagggc aatttcgttt ggttgattac catgcgtttt
     3421 catcccctct ggtttgttta caataatcaa gtgttgatct tgataaactt cctgcactaa
     3481 gtctgggttg ccccaaggga tcgtcttttg gggataatct tcctcgtcaa aagtcaactg
     3541 gcaaacatct ccaggattta cgatttcgtt ccagcggact tcttcttgat ttatcaaaat
     3601 atgtttcttg attctcaaaa aatgacggat ttttctaggg atgaggagtt gttcctcaag
     3661 taattgcttt accgtcattt gaggtagaga ggcgggtaat gtaaatgtga attgcataca
     3721 gatattgtaa caaaaaaagc cctatttgga taggaaatag ctaaattctt gtcttcctat
     3781 gatgaagatg ataaaataaa cgcatgaaat tagataaatt atttgagaaa tttctttctc
     3841 tttttaaaaa agaaacaagt gaactagagg actctgattc tactatctta cgtcgctctc
     3901 gtagtgatcg aaaaaaatta gcccaagtag gtccgattcg aaaattctgg cgtcgttatc
     3961 atctaacaaa gattatcctt atactaggtt tgagtgcagg cttgctagtt ggaatctatt
     4021 tgtttgctgt agccaagtcg accaatgtca atgatttgca aaatgccttg aaaactcgga
     4081 ctcttatttt tgaccgtgaa gaaaaagagg ctggtgcctt gtctggtcaa aagggaacct
     4141 atgttgagct gactgacatc agtaaaaact tgcagaatgc tgttattgcg acagaagacc
     4201 gttctttcta taaaaatgac gggattaact atggccgttt cttcttggct attgtcactg
     4261 ctggacgttc aggtggtggc tctaccatta cccaacagct ggctaaaaac gcctatttat
     4321 cgcaggatca aactgttgag agaaaagcga aagaattttt ccttgcctta gaattaagca
     4381 aaaaatatag taaggagcaa attctaacca tgtaccttaa caacgcttat tttggaaatg
     4441 gtgtgtgggg tgtagaagat gcgagtaaga aatactttgg agtttctgca tcagaagtga
     4501 gtctggatca agctgcgact ctggcaggga tgctcaaggg gccggaactg tataatccct
     4561 tgaattccgt agaagattct actaatcggc gcgatactgt cttgcagaat atggttgcag
     4621 caggatatat tgataaaaac caagaaaccg aagctgctga agttgatatg acttcgcaat
     4681 tgcacgataa gtatgaagga aaaatctcag attaccgtta cccctcttat tttgatgcgg
     4741 tggttaatga agctgtttcc aagtataatc taacagagga agagattgtc aataatggct
     4801 accgcattta cacagagctg gaccaaaact accaagcaaa tatgcagatt gtttatgaaa
     4861 acacatcgct atttccgagg gcagaggatg gaacgtttgc tcaatcagga agtgtagctc
     4921 tcgaaccgaa aacaggggga gttcgtggag ttgtcggtca agttgctgac aatgataaaa
     4981 ctggattccg gaatttcaac tatgcaaccc aatcaaagcg tagtcctggt tctacaatta
     5041 agcctttagt tgtttatacg ccagcagttg aagcaggctg ggctttgaat aagcagttgg
     5101 ataaccatac catgcagtat gacagctata aggttgataa ctatgcaggg atcaaaacga
     5161 gtcgagaagt tcctatgtat caagccttgg cagaatcgct taatctacct gctgttgcca
     5221 ctgttaatga tttgggtgtc gacaaggctt ttgaggcagg cgaaaaattc ggactcaaca
     5281 tggaaaaggt cgaccgtgtt cttggtgtcg ccttgggaag cggtgttgaa accaaccctc
     5341 ttcaaatggc tcaagcatac gctgcctttg caaatgaagg tttaatgcct gaagctcatt
     5401 ttattagtag aattgaaaat gctagtggac aagttattgc gaatcataaa aattcacaaa
     5461 aacgggtgat tgataagtct gtagctgaca agatgaccag tatgatgttg gggactttca
     5521 ccaacggtac cggtattagt tcatcgcctg cagactatgt catggcaggg aaaactggaa
     5581 caactgaagc agttttcaat ccggagtaca caagtgacca gtgggtaatt ggttatactc
     5641 cggatgtagt gattagccac tggcttggct ttccgaccac tgatgaaaat cactatctag
     5701 ctggctctac ttcaaacggt gcagctcatg tctttagaaa cattgccaat accattttac
     5761 cttatacgcc aggaagtacc tttacggttg aaaatgctta taagcaaaat ggaattgcac
     5821 cagccaatac aaaaagacaa gtacaaacca atgataatag ccagacagat gataatttgt
     5881 ctgatattcg agggcgtgcg caaagtctag tagatgaggc tagccgggct atctcagatg
     5941 cgaagattaa ggaaaaggct caaacaatat gggattcgat agtcaatcta tttcgctaag
     6001 atgcttgtca aagcctagct ttcttgttat aatggataag atggaggcgt tatggcacta
     6061 aaaaaagcaa gcctagcttg tgcggtttgt ggttcgagaa actattcaat caagatcagc
     6121 ggaaacccca agcctacacg actagaagta aataaatttt gtaagcattg tggcaagtac
     6181 actacacaca gagaaacgag ataggagaga gcgatgcgtt ttattggaga tatttttaga
     6241 cttcttaaag acacaacatg gccaactcgc aaggaaagct ggagagattt tcgttctatc
     6301 atggaataca cagctttctt tgtagtaatt atttacattt ttgaccagtt gattgtttca
     6361 ggtttgattc gatttattaa cattttttag aagattagtg gagttaatta cactagaaat
     6421 cttctattta tgaaaggaaa tatcatggat agttttgata aaggatggtt tgttttacaa
     6481 acttattctg gttatgaaaa taaggtgaaa gaaaatctat tacaacgtgc acaaacctac
     6541 aatatgttgg ataatattct acgcgttgaa attccaacac aaacagtgca agttgaaaaa
     6601 aatggaaaga gaaaagaagt agaagaaaat cgctttccag gttatgttct tgtagaaatg
     6661 gtcatgacag atgaagcttg gtttgttgtt cgaaacacac caaatgttac aggatttgtc
     6721 ggatcacacg ggaacagatc aaaaccaact ccattattgg aacaagaaat tcgtgacatt
     6781 ttggtatcta tgggacaaac tgttcaagaa tttgatttcg atgttgagat tggtcaaact
     6841 gtacgtatta ttgatggtgc ttttgcagac tacactggta agattacaga aattgataat
     6901 aacaaagtga aaatgattat ctctatgttt ggtaatgaca cagttgcaga agtaaaccta
     6961 aaccaaatcg cagaat
//
LOCUS       DAVHKZ010000069         6936 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000069 DAVHKZ010000000
VERSION     DAVHKZ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6936
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.069"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(1..866)
                     /locus_tag="VVO74_002119"
                     /pseudo
     CDS             complement(1..866)
                     /locus_tag="VVO74_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1075..2844
                     /locus_tag="VVO74_002120"
     CDS             1075..2844
                     /locus_tag="VVO74_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEU5696081.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     VAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            2868..4823
                     /locus_tag="VVO74_002121"
     CDS             2868..4823
                     /locus_tag="VVO74_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU5696082.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESI
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELIQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            4825..5262
                     /locus_tag="VVO74_002122"
     CDS             4825..5262
                     /locus_tag="VVO74_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU5696083.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            5324..6460
                     /locus_tag="VVO74_002123"
     CDS             5324..6460
                     /locus_tag="VVO74_002123"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEU5696084.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
BASE COUNT         2069 a         1188 c         1374 g         2305 t
ORIGIN      
        1 ttccattgtt ttagagcctt caaattggcc ttgaatgaga ttctctgctt tcttaccaac
       61 gtctccttta tgagaagaat attttcgttt ctgtcgcatt ttagcttgta aattgagtac
      121 ttttatcaag ccttgaactc ttttatgatt taccagataa gcacgatttc ttagttctaa
      181 atgaacccgg cgataagcat aatttccttt gtgttcgata aagatggatt gaatttcagc
      241 tttaagctct tggtccttat ctgttttgtc tagctgtttc aagtgatagt agtaggtcca
      301 acgagctagt ttaatggatt ttagaagaag aactaacgaa aactcagtca ttaattcttg
      361 aacaatttct gtccttcttc tttctctttt tcctccttca atcggagttc tcttaacttt
      421 tttaggatgg cattctccgc tctcaggtac tcattttctg cttgaagata ttctaattct
      481 gtcctctctt caggtctcgt ttttggctta cgtcccattt taggtactct ccctcttgtt
      541 ttctcaacaa tagtataccc gtttttcctg tattgtgcta gccagttaag aagtatcgta
      601 cgacttggga ggccgtattc aagagaaact ctatctttag tccagccttc atgtcagact
      661 ttattaatca tttcttgttt taaatcagga gaatagtaac gatttttccc ttttttgacg
      721 aactctattc cgtaacgatc aatcaattta atcatgtacc taagattaga attatttatc
      781 ccaaatttat ttgaaagctt ctctaagcta tatccttgct ttctaagttc atagatctga
      841 actttatcat cataagttaa tttcataata aaaacacccc aaaagttaga ttttttctgt
      901 ctaacttttg gggtgtagtt catgtacacc tgatatgatg cgttttataa tttttaagcc
      961 tttttgccca gcctcgtcaa aagtaatgtt ttgacacaaa atctgtgaca aaactttagt
     1021 tttaaaggtt tttaactttg tatatactag ttttaagaaa aggaggatga tctaatggaa
     1081 gaaaaagtat cattgaaggt cagggttcaa aaactaggga catcgctttc aaatatggtt
     1141 atgcccaata ttggagcatt tattgcttgg ggagtattga ctgccctctt tatcgctgat
     1201 ggctatctgc caaatgaaca gttagctact gttgttggtc ctatgttaac gtatttattg
     1261 ccaatcctga ttggttacac aggtggatat atgatccatg gccaacgtgg tgccgttgta
     1321 ggagctattg ctactgttgg tgcaatcaca ggttctagtg ttcctatgtt tatcggagct
     1381 atggtaatgg gcccactggg aggatggact atcaagaaat ttgatgagaa gttccaggaa
     1441 aaaattcgtc ccggatttga aatgttagtt aataacttct cagctggtct cgttggtttt
     1501 gcattattgc ttttggcttt ctacgcaatc ggtccagtcg tatcgactct tactgtagct
     1561 gttgggaatg gtgttgaggc tattgtcaat gctcgcctcc ttcctatggc taatattatc
     1621 atcgaaccgg ctaaagtcct ttttctcaat aatgccctca atcatggcat ttttactcct
     1681 ctgggagtag aacaggtagc tcaagctggt aagtcaattc tcttcctatt ggaagctaat
     1741 cctggaccag gcctgggaat tctattagct tatgctgtat tcggtaaagg ttctgctaaa
     1801 tcttcttctt ggggggcaat ggttattcat ttcttcggag ggattcatga aatttacttt
     1861 ccttatgtta tgatgaagcc tactctattt ttagctgcta tggcaggagg tatctctgga
     1921 acttttactt ttcaactctt agacgctggt cttaaatctc cagcttcacc aggttctatt
     1981 attgcgatta tggctacggc gccaaaaggt gtttggcctc atctaaatgt tcttttaggt
     2041 gttttagtgg cagcagttgt ttctttcctt gtagcagccc ttattcttca tgcagacaag
     2101 tcaactgagg attcgctcga agctgctcag gcggctaccc aagcagctaa ggctcagtct
     2161 aaaggtcagt tagtatcaac ttctgttgat gcagttgttt cgacagactc agtggaaaaa
     2221 atcattttcg cctgcgatgc tggtatggga agctctgcta tgggagctag tattcttcga
     2281 gataaggtta aaaaagcagg tctagagatt ccagtatcta atcaggcaat ctcaaatttg
     2341 cttgatacac caaaaacatt aattgttact caggaagaac tgacaccaag agctaaagac
     2401 aagagtccaa gtgctattca tgtttctgtt gataatttct tagcgtcccc tcgttatgat
     2461 gaaattgtag cttcattaac aggagctttt ccaatagcag aaattgaagg agatatacca
     2521 acttcagcac cagtagatag tcaggaaatt gaccttaacc atattgatgc tgtagtagtt
     2581 gcttatggta aagcacaggg aactgcaact atgggctgtg aaacgattcg ggctatcttt
     2641 agaaacaaga atattcgtat tccagtttct actgccaaaa tttcagaatt aggtgaattt
     2701 aattctaaaa acataatgat tgtaacaact atttctttac aggcagaagt gcagcaagca
     2761 gcaccgaatt ctcaatttct tattgtggat agtttagtaa caacaccaga atatgacaaa
     2821 atggctgcta gaatgtacaa atagaactag aggtttctaa attacgaatg ctattaacca
     2881 aacgagaaga acaattattg aaggctttcc tacatgtagg gaagctttca atgcaagata
     2941 tgactgaaat cttacaggtt tcatctagaa caatttatcg aactttatca gatttgacag
     3001 atagcatgga gcaatatgga atcgaaataa cgaagcatgg gaaatactat attttgactg
     3061 gagagttgga tgatttgccg acagaacttg aagtgttagt tgagtatagt ccccaagaaa
     3121 gacaagagtt gattacctat cgccttctga ctgagagcgg ttttgtcacc aatgaagcat
     3181 tgcaagagtg cacgaaagtc agtaatgtaa ctattattca ggatatttca gatattgata
     3241 agcgtctttt agactttgat ctgaaaattg aacgacaaaa aggttatcgg atttctggtg
     3301 attcagttgg taagagaaga tttttggcta ttttactgac aaactgtatc tcagtagcag
     3361 atttttcaac cggtaatttt gggagctttg atattttaga agcagataga actaggctgg
     3421 ccagtcagat tgttaataag caactgtcag gttttccaga tatggatgct aggatgaaga
     3481 tgttttttgc gatcttgtta tctcttatag gtcaggagca aaacattgaa aattcaccta
     3541 atactagtaa gcaggctttg gaaatttctc aaaaaatttt tcaagcttac tctaagcaga
     3601 ctgcacaatt ttatagtatt caggaaatta tctattttgc gagcatcttg gatgaattaa
     3661 tcattaaacg tcaggacaat ccgctcttta cggagaaatt tgatggtgaa tttttctaca
     3721 atatttcaaa tctgattgat acggtttcca tgtataccaa gattgacttt tttaaggaca
     3781 aggttttatt caattttctt ttccatcata ttcggctcag tttaggcgtc cctatccttt
     3841 ttcagggtga aaatttgcca gaatctatcc agattttagt tgaaaggaat aaatttcttt
     3901 atacagtcat cagtctttta gtgaatgata tttttccgaa atatcttcat acagagtatg
     3961 agtatggcat gattgcccta cattttatct ctagcttagg ccgtagtcca gagatttatc
     4021 cagtccgtgt tttgctttta acggatgaac gtcgggtcac tagagattta ttagtcagta
     4081 aaattaagag tgttgctcct tttgtagagt tgatagatat tcagtctcta gtagattacc
     4141 acagtattga tctcagtcag tatgattata ttttatctac caagccgctg actaatcagg
     4201 aaatcgatgt aatttctagt tttccaaccg tcaaagaatt gcttgaatta caggaacgac
     4261 ttcagtatgt acaggcacat cgtacaattg tcgcgcgtga tgctatcgct ccagagaaaa
     4321 gttatgactt gcaagattat ttaatatcta gtagtcagct tttgagtcaa tttgagttga
     4381 ttcaattgga gaataatcaa tcatttgagc acacggtaga acaaatcatc caatatcaga
     4441 agaatgtgag tgacagagat tacctaacaa gaaaattgtt atctcacttc cagaatagtc
     4501 ctatggctat tcctaatact ggtctggtgc ttttacatag tcagtctagc aaagtaacaa
     4561 caaatagttt tactatgttt gaactcaaac tacctatctc cgcattgtca atgaaacgag
     4621 aggaagaaga ggtcaaaagg tgtctgctaa tgctaatgtc taaagaagct agcgaggaag
     4681 cgagagattt aatgacagct attagtcagt cgattattga aaatcatctt tatacagaga
     4741 tttacaagac gggaaatcaa tccattattt atcagatgct aaatactatt tttaacgaaa
     4801 aaattaagaa attggagaac taatatgaaa cttgaaaaac atttgattaa gcttaataaa
     4861 caattttcta acaaggagga agctatttgt tattgtgggc aagttcttta tgagggtgga
     4921 tatgttaatg aagactatat tgaagccatg attgagcgag ataaagagct atctgtttac
     4981 atgggtaact ttatcgccat accgcatgga acagatgcag caaaaaagga tgtactcaag
     5041 tctggtatta cagtcgttca agtccctaga ggggttgatt ttgggaatgt atctaaccct
     5101 caagtggcaa cggttctttt tggtattgct ggtattggta atgaacactt agaaattatt
     5161 cagaaaattt ctatcttctg tgcagatgta gataatgttc ttaaactagc agatgctcag
     5221 tcaaaagagg aagtattgcg cttatttgat gctgttgaat aattgaattt cgtcatttgt
     5281 catctagtat atatgtccct caaataggaa aaggagaaat tgaatgaaac attctgttca
     5341 ttttggtgcc ggtaatatcg gtcgtggttt tataggtgaa attctattta aaaatggttt
     5401 ccatattgat tttgtggatg tcaataatca gataattcat gctctaaatg aaaagggcaa
     5461 gtatgaaatt gaaattgcac agaaaggaca gtctcgtata gaagtaacta atgtggctgg
     5521 cattaatagc aaagaacatc ctgagcaagt cattgaagcg attcaaaaga cggatattat
     5581 tactactgca atcggaccta atatactccc ttttatcgcc gaacttctag ccaaaggaat
     5641 cgaagctcgc cgagttgcag gaaatacaca ggcattggat gttatggcct gtgaaaatat
     5701 gattggcggg tctcaatttc tttatcaaga agtcaagaaa tatttaagtc cggaaggttt
     5761 gacatttgct gataactaca taggttttcc aaatgctgca gtagacagga ttgttccagc
     5821 acaaagtcac gaagattccc tttttgttgt ggtcgagccc tttaatgaat gggtcgtgga
     5881 aaccaagcgt cttaaaaatc cagatttacg tctaaaagat gtgcattatg aagaagattt
     5941 agaacccttt attgagcgaa aacttttttc agtcaattct ggacatgcaa cttcagctta
     6001 cattggtgcg cattatggtg ccaagacaat tttggaagct cttcaaaatc ctaatattaa
     6061 atctcggatt gaatctgtat tagctgaaat tcggagtctc ttgattgcca aatggaactt
     6121 tgataaaaaa gaattggaga attatcacaa agtcattata gaacggtttg aaaacccttt
     6181 catagtggac gaggttagtc gcgtagctcg tactccaatc cgaaaattag gctataatga
     6241 acgattcatc cggccgatac gtgaattgaa agaactcagt ttgtcatata aaaacctact
     6301 taaaacagtt ggctatgcct ttgactatcg cgatgtaaat gatgaagaaa gtattcgatt
     6361 aggtgaattg ttggctaaac aatcagtcaa agatgttgtt atacaagtta caggtttaga
     6421 cgaccaagaa ttgattgagc aaattgtaga gtatatttaa tctttttcga aaatctcttc
     6481 aaatcaggtt agcatcgctt tgtcttaggc atatgttgtt ctatctacaa cctcaaagca
     6541 gtgctttgag ctgactccgt cagtcttgtc tgcaacctca aaacactgtt tgagttatct
     6601 gcggtaatct ttctagcttg tctttgattt ttgttgttat ttataaggta aaagaagctg
     6661 gacaaaaagt cttcaaaatc ggaaaaaggc agcctatcgg gtgttcaaaa atcttgatag
     6721 gatgtccttt attatggaaa gccttattgg attttctcct cagattgagt ttttgatcag
     6781 ctttatgaga taggttttgc tagagatgta gcccatcatg ttatttttat ggacggtggg
     6841 aaaattgttg aaaaaaataa tgcccatcaa ttctttagtc gtccaagaga agaacgaacc
     6901 aagcaatttt ggaacgaatt ctttcgaatg cgatct
//
LOCUS       DAVHKZ010000070         6326 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000070 DAVHKZ010000000
VERSION     DAVHKZ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6326
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.070"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            302..1847
                     /locus_tag="VVO74_002124"
     rRNA            302..1847
                     /locus_tag="VVO74_002124"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1899..1971
                     /locus_tag="VVO74_002125"
     tRNA            1899..1971
                     /locus_tag="VVO74_002125"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1932..1934,aa:Ala,seq:tgc)
     gene            2096..4997
                     /locus_tag="VVO74_002126"
     rRNA            2096..4997
                     /locus_tag="VVO74_002126"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5074..5189
                     /gene="rrf"
                     /locus_tag="VVO74_002127"
     rRNA            5074..5189
                     /gene="rrf"
                     /locus_tag="VVO74_002127"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            5194..5266
                     /locus_tag="VVO74_002128"
     tRNA            5194..5266
                     /locus_tag="VVO74_002128"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5227..5229,aa:Val,seq:tac)
     gene            5269..5341
                     /locus_tag="VVO74_002129"
     tRNA            5269..5341
                     /locus_tag="VVO74_002129"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5302..5304,aa:Asp,seq:gtc)
     gene            5366..5438
                     /locus_tag="VVO74_002130"
     tRNA            5366..5438
                     /locus_tag="VVO74_002130"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5399..5401,aa:Lys,seq:ttt)
     gene            5444..5525
                     /locus_tag="VVO74_002131"
     tRNA            5444..5525
                     /locus_tag="VVO74_002131"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5478..5480,aa:Leu,seq:tag)
     gene            5544..5616
                     /locus_tag="VVO74_002132"
     tRNA            5544..5616
                     /locus_tag="VVO74_002132"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5577..5579,aa:Thr,seq:tgt)
     gene            5639..5710
                     /locus_tag="VVO74_002133"
     tRNA            5639..5710
                     /locus_tag="VVO74_002133"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5671..5673,aa:Gly,seq:gcc)
     gene            5718..5803
                     /locus_tag="VVO74_002134"
     tRNA            5718..5803
                     /locus_tag="VVO74_002134"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5752..5754,aa:Leu,seq:taa)
     gene            5813..5886
                     /locus_tag="VVO74_002135"
     tRNA            5813..5886
                     /locus_tag="VVO74_002135"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5847..5849,aa:Arg,seq:acg)
     gene            5902..5975
                     /locus_tag="VVO74_002136"
     tRNA            5902..5975
                     /locus_tag="VVO74_002136"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5936..5938,aa:Pro,seq:tgg)
     gene            5981..6054
                     /locus_tag="VVO74_002137"
     tRNA            5981..6054
                     /locus_tag="VVO74_002137"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6015..6017,aa:Met,seq:cat)
     gene            6068..6141
                     /locus_tag="VVO74_002138"
     tRNA            6068..6141
                     /locus_tag="VVO74_002138"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6102..6104,aa:Ile,seq:cat)
     gene            6152..6241
                     /locus_tag="VVO74_002139"
     tRNA            6152..6241
                     /locus_tag="VVO74_002139"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6188..6190,aa:Ser,seq:tga)
     gene            6252..6325
                     /locus_tag="VVO74_002140"
     tRNA            6252..6325
                     /locus_tag="VVO74_002140"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6286..6288,aa:Met,seq:cat)
BASE COUNT         1724 a         1316 c         1844 g         1442 t
ORIGIN      
        1 acaccgcctt ttcacggcgg taacacgggt tcgaatcccg tacggactat ggtatgttgc
       61 ggttggaaca cttgatgaaa aaaagtttaa aaaaacttaa aaatcttcaa aaaagtgttg
      121 acaagtgaaa gtggctgtga tatactaata tagttgtcgc ttgagagaag caagtgacaa
      181 agacctttga aaactgaaca agacgaacca atgtgcaggg cgctacaaca taagttgtag
      241 tactgaacaa tgaaaaaaac aataaatctg tcagtgacag aaatgagtaa gaactcaaac
      301 ttttaatgag agtttgatcc tggctcagga cgaacgctgg cggcgtgcct aatacatgca
      361 agtagaacgc tgaaggagga gcttgcttct ctggatgagt tgcgaacggg tgagtaacgc
      421 gtaggtaacc tgcctggtag cgggggataa ctattggaaa cgatagctaa taccgcataa
      481 gagtggatgt tgcatgacat ttgcttaaaa ggtgcacttg catcactacc agatggacct
      541 gcgttgtatt agctagttgg tggggtaacg gctcaccaag gcgacgatac atagccgacc
      601 tgagagggtg atcggccaca ctgggactga gacacggccc agactcctac gggaggcagc
      661 agtagggaat cttcggcaat ggacggaagt ctgaccgagc aacgccgcgt gagtgaagaa
      721 ggttttcgga tcgtaaagct ctgttgtaag agaagaacga gtgtgagagt ggaaagttca
      781 cactgtgacg gtatcttacc agaaagggac ggctaactac gtgccagcag ccgcggtaat
      841 acgtaggtcc cgagcgttgt ccggatttat tgggcgtaaa gcgagcgcag gcggttagat
      901 aagtctgaag ttaaaggctg tggcttaacc atagtaggct ttggaaactg tttaacttga
      961 gtgcaagagg ggagagtgga attccatgtg tagcggtgaa atgcgtagat atatggagga
     1021 acaccggtgg cgaaagcggc tctctggctt gtaactgacg ctgaggctcg aaagcgtggg
     1081 gagcaaacag gattagatac cctggtagtc cacgctgtaa acgatgagtg ctaggtgtta
     1141 gaccctttcc ggggtttagt gccgtagcta acgcattaag cactccgcct ggggagtacg
     1201 accgcaaggt tgaaactcaa aggaattgac gggggcccgc acaagcggtg gagcatgtgg
     1261 tttaattcga agcaacgcga agaaccttac caggtcttga catccctctg accgctctag
     1321 agatagagtt ttccttcggg acagaggtga caggtggtgc atggttgtcg tcagctcgtg
     1381 tcgtgagatg ttgggttaag tcccgcaacg agcgcaaccc ctattgttag ttgccatcat
     1441 tcagttgggc actctagcga gactgccggt aataaaccgg aggaaggtgg ggatgacgtc
     1501 aaatcatcat gccccttatg acctgggcta cacacgtgct acaatggctg gtacaacgag
     1561 tcgcaagccg gtgacggcaa gctaatctct taaagccagt ctcagttcgg attgtaggct
     1621 gcaactcgcc tacatgaagt cggaatcgct agtaatcgcg gatcagcacg ccgcggtgaa
     1681 tacgttcccg ggccttgtac acaccgcccg tcacaccacg agagtttgta acacccgaag
     1741 tcggtgaggt aaccgtaagg agccagccgc ctaaggtggg atagatgatt ggggtgaagt
     1801 cgtaacaagg tagccgtatc ggaaggtgcg gctggatcac ctcctttcta aggataagga
     1861 actgcgcatt ggtcttgttt agtcttgaga ggtcttgtgg ggccttagct cagctgggag
     1921 agcgcctgct ttgcacgcag gaggtcagcg gttcgatccc gctaggctcc attggtgaga
     1981 gatcaccaag taatgcacat tgaaaattga atatctatat caaatagtaa caagaaaata
     2041 aaccgaaaac gctgtagtat taataagagt ttatgactga aaggtcagaa aataaggtta
     2101 agttaataag ggcgcacggt ggatgccttg gcactaggag ccgacgaagg acgtgacaaa
     2161 cgacgatatg ccttgggtag ctgtaagtaa gcgatgatcc agggatttcc gaatggggga
     2221 acccaacagg taatacctgt tacccacatc tgttaaggat gtgaggagga agacgcagtg
     2281 aactgaaaca tctaagtagc tgcaggaaga gaaagcaaaa gcgattgcct tagtagcggc
     2341 gagcgaaacg gcagaagggc aaaccgaaga gtttactctt cggggttgta ggactgcaat
     2401 gtggactcaa agattataga agaatgattt gggaagatca gccaaagaga gtaatagcct
     2461 cgtatttaaa atagtctttg tacctagcag tatcctgagt acggcgggac acgtgaaatc
     2521 ccgtcggaat ctgggaggac catctcccaa ccctaaatac tccctagtga ccgatagtga
     2581 accagtaccg tgagggaaag gtgaaaagca ccccgggagg ggagtgaaat agaacctgaa
     2641 accgtgtgcc tacaacaagt tcgagcccgt taatgggtga gagcgtgcct tttgtagaat
     2701 gaaccggcga gttacgttat gatgcgaggt taagttgaag agacggagcc gtagggaaac
     2761 cgagtctgaa tagggcgcct tagtatcatg acgtagaccc gaaaccatgt gacctaccca
     2821 tgagcaggtt gaaggtgcgg taagacgcac tggaggaccg aaccagggca cgttgaaaag
     2881 tgcttggatg acttgtgggt agcggagaaa ttccaaacga acttggagat agctggttct
     2941 ctccgaaata gctttagggc tagcgtcgac attagagatt cttggaggta gagcactgtt
     3001 tgggtgaggg gtccatcccg gattaccaat ctcagataaa ctccgaatgc caatgaatta
     3061 tggtcggcag tcagactgcg agtgctaaga tccgtagtcg aaagggaaac agcccagacc
     3121 accagctaag gtcccaaaat aattgttaag tggaaaagga tgtggggttg cacagacaac
     3181 taggatgtta gcttagaagc agctattcat tcaaagagtg cgtaatagct cactagtcga
     3241 gtgaccctgc gccgaaaatg taccggggct aaaacaattt accgaagctg tggatacctt
     3301 tataggtatg gtaggagagc gttctatgtg tgatgaaggt ataccgtgag gagtgctgga
     3361 acgcatagaa gtgagaatgc cggtatgagt agcgaaagac aggtgagaat cctgtccacc
     3421 gtaagactaa ggtttccagg ggaaggctcg tccgccctgg gttagtcggg acctaaggag
     3481 agaccgaaag gtgtatccga tggacaacag gttgatattc ctgtactaga gtatgtagtg
     3541 atggagggac gcagtaggct aactaaagca gacgattgga agagtctgtc taagcagtga
     3601 ggtgtgaatt gagtcaaatg cttaattcta taacattgag ctgtgatggg gagcgaagtt
     3661 tagtagcgaa gttagtgacg tcacactgcc aagaaaagct tctagcgttt aaacatactc
     3721 tacccgtacc gcaaaccgac acaggtagtc gaggcgagta gcctcaggtg agcgagagaa
     3781 ctctcgttaa ggaactcggc aaaatgaccc cgtaacttcg ggagaagggg tgctgacttt
     3841 aagtcagccg cagtgaatag gcccaagcaa ctgtttatca aaaacacagc tctctgctaa
     3901 atcgtaagat gatgtatagg gggtgacgcc tgcccggtgc tggaaggtta agaggagtgc
     3961 ttagcgtaag cgaaggtatg aattgaagcc ccagtaaacg gcggccgtaa ctataacggt
     4021 cctaaggtag cgaaattcct tgtcgggtaa gttccgaccc gcacgaaagg cgtaatgatt
     4081 tgggcactgt ctcaacgaga gactcggtga aattttagta cctgtgaaga tgcaggttac
     4141 ccgcgacagg acggaaagac cccatggagc tttactgcag tttgatattg agtgtctgta
     4201 ccacatgtac aggataggta ggagtctaag agatcgggac gccagtttcg aaggagacgc
     4261 tgttgggata ctacccttgt gttatggcca ctctaaccca gataggtgat ccctatcgga
     4321 gacagtgtct gacgggcagt ttgactgggg cggtcgcctc ctaaaaggta acggaggcgc
     4381 ccaaaggttc cctcagaatg gttggaaatc attcgcagag tgtaaaggta taagggagct
     4441 tgactgcgag agctacaact cgagcaggga cgaaagtcgg gcttagtgat ccggtggttc
     4501 cgtatggaag ggccatcgct caacggataa aagctaccct ggggataaca ggcttatctc
     4561 ccccaagagt tcacatcgac ggggaggttt ggcacctcga tgtcggctcg tcgcatcctg
     4621 gggctgtagt cggtcccaag ggttgggctg ttcgcccatt aaagcggcac gcgagctggg
     4681 ttcagaacgt cgtgagacag ttcggtccct atccgtcgcg ggcgtaggaa atttgagagg
     4741 atctgctcct agtacgagag gaccagagtg gacttaccgc tggtgtacca gttgtcttgc
     4801 caaaggcatc gctgggtagc tatgtaggga agggataaac gctgaaagca tctaagtgtg
     4861 aaacccacct caagatgaga tttcccatga ttatatatca gtaagagccc tgagagatga
     4921 tcaggtagat aggttagaag tggaagtgtg gcgacacatg tagcggacta atactaatag
     4981 ctcgaggact tatccaaagt aactgagaat atgaaagcga acggttttct taaattgaat
     5041 agatattcaa ttttgagtag gtattactca gagttaagtg acgatagcct aggagataca
     5101 cctgtaccca tgccgaacac agaagttaag ccctagaacg ccggaagtag ttgggggttg
     5161 ccccctgtga gatagggaag tcgcttagct ctagggagtt tagctcagct gggagagcat
     5221 ctgccttaca agcagagggt cagcggttcg atcccgttaa ctcccaaagg tcccgtagtg
     5281 tagcggttat cacgtcgccc tgtcacggcg aagatcgcgg gttcgattcc cgtcgggacc
     5341 gtttaagata acgcaagtta ttttagactc gttagctcag ttggtagagc aattgacttt
     5401 taatcaatgg gtcactggtt cgagcccagt acgggtcata tatgcgggtt tggcggaatt
     5461 ggcagacgca ccagatttag gatctggcgc ttaacggcgt gggggttcaa gtcccttaac
     5521 ccgcattaag atataacaaa tgagccggct tagctcagtt ggtagagcat ctgatttgta
     5581 atcagagggt cgcgtgttca agtcatgtag ccggcatttt tagatagaag aaaacagtgc
     5641 gaacgtagtt cagtggtaga acaccacctt gccaaggtgg gggtcgcggg ttcgaatccc
     5701 gtcgttcgct tagagaggcc ggggtggcgg aactggcaga cgcacaggac ttaaaatcct
     5761 gcgattggta acgatcgtac cggttcgatt ccggtcctcg gcataatatg gagcaccctt
     5821 agctcaactg gatagagtac ctgactacga atcaggcggt tagaggttcg actcctctag
     5881 ggtgcatttt tctttttaac tcgggaagta gctcagcttg gtagagtact tggtttggga
     5941 ccaaggtgtc gcaggttcga atcctgtctt cccgattcat ggcggtgtag ctcagctggc
     6001 tagagcgtcc ggttcatacc cgggaggtcg ggggttcgat ccccttcgcc gctataatga
     6061 tcttgtcgga cctttagctc agctggttag agctctcggc tcataaccga gtggtcgtag
     6121 gttcaagtcc tacaaggtcc atttgaatat tggaggatta cccaagtccg gctgaaggga
     6181 acggtcttga aaaccgtcag gcgtgtaaaa gcgtgcgtgg gttcgaatcc cacatcctcc
     6241 ttttatatta acgcgggatg gagcagctag gtagctcgtc gggctcataa cccgaaggtc
     6301 gtaggttcaa atcctgctcc cgcaat
//
LOCUS       DAVHKZ010000071         6112 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000071 DAVHKZ010000000
VERSION     DAVHKZ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6112
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.071"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(7..1362)
                     /gene="rlmD"
                     /locus_tag="VVO74_002141"
     CDS             complement(7..1362)
                     /gene="rlmD"
                     /locus_tag="VVO74_002141"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU5696085.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1400..2176
                     /gene="recX"
                     /locus_tag="VVO74_002142"
     CDS             1400..2176
                     /gene="recX"
                     /locus_tag="VVO74_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU5696086.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQVSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2265..2798
                     /locus_tag="VVO74_002143"
     CDS             2265..2798
                     /locus_tag="VVO74_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU5696087.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(3156..3641)
                     /locus_tag="VVO74_002144"
                     /pseudo
     CDS             complement(3156..3641)
                     /locus_tag="VVO74_002144"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(3679..4011)
                     /locus_tag="VVO74_002145"
     CDS             complement(3679..4011)
                     /locus_tag="VVO74_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5696088.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADSISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEHYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKNS"
     gene            complement(4024..4797)
                     /locus_tag="VVO74_002146"
     CDS             complement(4024..4797)
                     /locus_tag="VVO74_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU5696089.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAN
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            complement(5244..5999)
                     /locus_tag="VVO74_002147"
                     /pseudo
     CDS             complement(5244..5999)
                     /locus_tag="VVO74_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
BASE COUNT         1977 a         1110 c          944 g         2081 t
ORIGIN      
        1 ccttttttaa acttttttta ttaattttac aacagcttca gttcgagctg tatgtgggaa
       61 catatcgacc gactggatat aatgaagatc atagacttct actaagcgta ccaaatcacg
      121 agccaaggtc gaaacattac aagaaatata aaccattttt tctggtacat aagtaagaat
      181 agtatctaat aacttatcat ccagacctgt acgtggtggg tcaacaatca aagcatctgc
      241 tcggtagcct tccttgtacc aacgaggaat aatctcttct gccgttccag cttcataatg
      301 agtattgtca aatcccattc ttttagcatt tcgcttggca tcttcaatag cttctggaat
      361 aatatccata cctctgagtg tttttacttt ctttgcaaag gcaaatccaa tcgttccaac
      421 tccacaataa gcgtcaatca aatggtcttc tttatcaaca tccagcgctt ttactgcttc
      481 gctatagagg acttctgttt gctcaggatt tagttgataa aaagctcgag gggatagtga
      541 aaattcataa ttgagtacac cttcttgaat actctcttgc ccccagataa tctctgtctt
      601 ttcaccatat atctcactgg ttttagctgt atttgtatta acagctactg tcacaacttc
      661 tgggaaatct ttaaccaact cttttaccaa ttgagttaaa ttaagctggc ggtttgtaac
      721 aataataatc tgaacctgtc cggtctttct cgcgcgtcgg accataatag tacggacacc
      781 tagaactttt ctctcatccg tgattggaat ctggtgataa gtaagtaatt ctgctaagcg
      841 attagcaatc acttgggttt ccttatcttg taccaggcag tctttcaact ctactaaata
      901 gtgagagttt tgtgcatata agcccgcctt gacctgattt ttaaattttc gagtctgaaa
      961 ttgtaactta gctctgtaat attttggttc ctgcattcca atagttggac gaatttcata
     1021 attttcatat cctgcaggag caaatttttt cagcgcttga tgaagtaagt ccgtcttgaa
     1081 ctccagctgc ttatcataat gcaggtgcat gatttggcag cctccgcatt cattataaat
     1141 agtacaagat ggcacaattc gaaatttaga cttcttgttg accttcagta attttgcttc
     1201 aacaaagttg cgtctaatag aagtaatctg acaatagata tcttcgcctt tgagagctcc
     1261 aggtacaaag actaatgttt tttggtaaaa gccgattccc tcaccgttaa ttcccatgcg
     1321 cttgattttt aatggtattt tttgtttcac tttcagattc atacccctat cttatcacat
     1381 tttgagttat aatagagcta tgaaaatcac aaaacttgaa aagaaaaaaa gactctatct
     1441 gatggagctt gataatggcg acaaatgcta tatcaccgaa gatacaattg ttcgttttat
     1501 gttatcgaga gataaggtga taagcgaaga ggaattgaaa gagattcaag actttgctca
     1561 attttcttat ggtaagaatc tggccctcta ccacttatcc tttaaagcac gcactgaaaa
     1621 agaagtcaga gaatatctga aaaaatacga tattgataaa aacatcgttt ctcaagttat
     1681 tgctaatctt aaagaagata agtggattaa tgatggtcag tacgcttatg ctatcatcaa
     1741 tgccaatcaa gtttcaggag acaagggacc ttatgtactg actcagaaat tagcacaaaa
     1801 aggaatttca aaatctacta tagaagaaat cttgaatgat tttgattttt cggaagttgc
     1861 tcaacgtgta gccaataaac tattgaaaaa atatgaggga aaacttccag ctcgtgccct
     1921 gcaagataag attatccaga acttgactaa caagggcttc tcttattttg atgctaaaat
     1981 tgcctttgac gaattggata gtcaagttga ccaagaaacg actcaggaac tcatcttcaa
     2041 ggaacttgat aagcaatata ctaagtatgc ccgaaagtat gaaggatacg aactgaagca
     2101 gcgtttaact caagttttag cacgaaaggg ctacgatttt tcggatatag caagcgctct
     2161 tagagaatat ctttaatatt tccaagtgaa attcacagat tttaggtaat tttatggtac
     2221 aatagtaaat gataaactta taaattgtag aaagttggtt agttatgaag cttccaaaag
     2281 aaggcgactt tattacaatt caaagttata agcatgatgg gagtctccac cgaacttggc
     2341 gggacaccat ggtactaaaa acaacagaaa acgccattat tggtgtcaac gatcatacac
     2401 ttgttaccga aagtgatggt cgtcgttggg tcactcgaga accggctatt gtttactttc
     2461 acaagaaata ttggtttaat atcattgcca tgattcgtga taatggaact tcttactatt
     2521 gcaatatggc tagcccctac tatctggatg aagaagcact gaagtatatt gattacgatt
     2581 tggatgttaa aatttttaca gatggggaaa aacgtctctt ggacgttgaa gaatacgagc
     2641 gtcacaaacg caaaatgaat tattctgatg acttggacta tattttaaaa gaacatgtca
     2701 aaattcttgt tgattggatt aacaatggac gtggtccttt ctcagaagcc tatgtaaaca
     2761 tttggtacaa gcgctatgta gaactaaaga atcggtaaag ttgtcaaagg tcaggaacaa
     2821 aatcctgacc ttgttttttt ggtagtataa aataaattgt gtaaacacaa aaaggaataa
     2881 atccattata gcagagttac aacacattac tagaaagaga tttatgcaga attcgtaaaa
     2941 tatataaaac aaatagatat actattattt tttaatgtct ttattcctag taagtttaca
     3001 acaaacttat atcgtttaat acaaaaaata cgaaaatgat tagtataaaa aatacaggtc
     3061 aacttcgtat caaaaacatt tttttgtatt tccacatagc atcaatcatt tagtacaata
     3121 ttttaaaaac aatatcttaa cagagaaaat gatatttaat ctatcagctc atttaatcgt
     3181 ttttgaaaat ataaagcaat acttttagat tcaataaact caaaatattt tatgacattg
     3241 tccatttgtt taattccaga ttctttagat tctgtcaggt atattttata tccttctaca
     3301 aatttgaatg tagatttttc aaaaactttt gtgtcatctt ttaataattt ttgtaatttc
     3361 atttcaaagt agtctgcata tattagatgt gaattttcaa ggcaacagaa ccaaaaattt
     3421 aaacaagctg acacaactaa atgtctattc ttgccgattt tttcgtaata atgtgtacgc
     3481 tctagtattt cttttccgac catgtaaata taatctattt caaaaagatg atataaatta
     3541 ccaatcagcg ttatctcata ggacttccat cgttccttct ggaataaata gtcatatact
     3601 aaatttagat catctctact aactacatga ttacaatcta gctgatttca taatccctga
     3661 accataattg tatttatttt atgagttttt cccactcttc tcaaaaagtt tttgttgctt
     3721 attttttatt acctccaatc ctttaatatt caaactataa aaatttggag ataaattaac
     3781 caaaaaatca tcacgctccg atcttttata atgttctaag tgattacaaa aattctctat
     3841 cgaaacattg atatttgata ataattcaaa aaatgttgaa agagaaattt cattttctcc
     3901 cctttcaaat ctagaaagtt gagattttga tatagaatca gctgcagcat actctaaaga
     3961 atatccgttt aattttctaa aatatcgaaa agcttctccg taatttttca cactttcatt
     4021 cccttaactt tcttttcgag cgataaacat accatattct ttaggaatga tcaacatacc
     4081 attattaaac tcactttcca atcttttacg tattatttcc tcttctagtg aacctatttc
     4141 tgaaattcct ttaaacgatt ggatgtattt aactaggtca tctatactag ttacctgtaa
     4201 ctcatcatca tagagtaatg tatcgacaga gttaaaatac ctactcaggt accttttacc
     4261 attttgtaaa gtaaacgttc tattttctaa atcttgatta acctcatctt taaataaatt
     4321 tgccaaataa tttacaactc cattttcacc aaatgtagca cagtaaaaaa ttcctccggt
     4381 ttttaagacc ctattcacct cagagagagc tttaggaata tcattcacat gatgtagaag
     4441 catattagca ataacaatat caaaagtttc attctcaaaa gaaatctttt gaatatccat
     4501 tatctcataa ttgacattgt ttctatttcc aatcactgac ttcgttgatt ttaccatatc
     4561 tttagaaaaa tctgtaacaa tcaactgctt cattttatct atagaatcac tattactttt
     4621 ccacaattct cctgtaccac atcccaattc tagaaccttt acttcatcag tgatttggta
     4681 gttagaaaat atccaattat taaatcccaa tttatttttt gaatacttct tatgcaattc
     4741 tactcgaata tcaagattat catgactttt atattgttca attactttat caatcatttt
     4801 aaatgacctc cactctataa tttggcatta tatcacaaga ataaagatag tgttaaataa
     4861 gttgtataaa tgcaaaaaag gaatattccg ttatagcaga gttgtaacac atttctataa
     4921 agaaatttat tcctacgact cagtttggca tgcttaactt cctaactcaa aaacaaagca
     4981 tcgattaatt tatccgttct tcttttgaaa cagatttgaa ctgataattg ctcgttttaa
     5041 tttaagaagc tcttttgagc aaaacttcat ttttttaaga gtccaacaat ttctgtctat
     5101 cgcttttcta ctagcaaaaa aaactacctt gaggcaagtt ttcatttata tatctaattt
     5161 cgtaatagta tagtaaaatg aaataaggac agtcaaatcg atttctaaca atgttttaga
     5221 agtaaaggtg tactattcta gtttcaatct actataaatt tgatatgaga atagtctttc
     5281 tcaacatcct tacccaacaa gaatgctgta gcgtccttct taacttgaac caggtcaata
     5341 ttctgggctt gggctgcata gacgcagcca caataacatt gacgatagat atcatactcc
     5401 tcacacatct ctactgaacg tttgtagcct tgatttttct tgaaatcgtt gggaagatag
     5461 tgggtcgtgt aaattttttg cacatcgatt ccgatgctgt tgatggtttg agaattctta
     5521 tgaggactga tggtcaaggc tgaaccaaag tagtcaaagc ccaagtccat agccacttgc
     5581 gctgttttat ccagtcggta gtcaaaacaa accttgcaac ggtcgccacc ttcgggctcc
     5641 tcctctagtc ccctaactag ttttcggtat taattgggtt cgtagggagc ttctaggtac
     5701 tgaaccgtat ttcctgtccg ctcattaaaa tcactaacaa atttcttgat gacatagacc
     5761 cgcttatggt attctacctt gggatggata ttagaattgg caaaatagat ggtcacatct
     5821 gcatacttgg tcaaatattc tagtgtatag gtactacaag gggcacagca aacatgcacg
     5881 agaatggttg gccgctgctc atttttctcc catgcttgta ccattttctg catgacacgg
     5941 tcataattaa tcttctgatt ggggggcatc ttgcacagaa tttcttctac atcgatcatg
     6001 ttcttctcct ttttctagtc ttattttatc atataagtta ggagagctca aatcaattta
     6061 gaagtgaata ttataaaaag aagggttagt cattccctcc ttttgtgttt tt
//
LOCUS       DAVHKZ010000072         5457 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000072 DAVHKZ010000000
VERSION     DAVHKZ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5457
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.072"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            60..1202
                     /locus_tag="VVO74_002148"
     CDS             60..1202
                     /locus_tag="VVO74_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU5696090.1"
                     /translation="MWMEELPNGKYKFFERYKDPYTEKWKRVSVTLDSGSSRAKKEAQ
                     KLLDERLEETLKKIQTTDIVYEHILDEWWTFYQKEIKGSSISSLTSSVNDFKKDFDLS
                     VKVSNIDTKYIQRFLNDLDLSRSKLERYKLILNLSLDYAVNLEYIEDNPARRAKLPKL
                     VKTIEDLEKTEKKFLEEDELERLLSELYRTDKTYRLGLLAEFMAYNGCRIGEAIALRK
                     ENIDFESKTVKINGTLDKTVGYSKGLKTTTKTAASFRTVSLSKRELEILKEFISINEL
                     SKNTRETFKDLGFIFVTKNGIPIQNNSFNLAIQKVNNRLKNPINKHLTSHIFRHTLVS
                     RLSENNVPLKAIMARVGHSDSRTTNKIYTHVTKKMDDNILNLLDNL"
     gene            complement(1289..1564)
                     /locus_tag="VVO74_002149"
     CDS             complement(1289..1564)
                     /locus_tag="VVO74_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU5696091.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(1671..2510)
                     /locus_tag="VVO74_002150"
     CDS             complement(1671..2510)
                     /locus_tag="VVO74_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU5696092.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQVYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            2652..3500
                     /locus_tag="VVO74_002151"
     CDS             2652..3500
                     /locus_tag="VVO74_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU5696093.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFIFGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(3593..4510)
                     /locus_tag="VVO74_002152"
     CDS             complement(3593..4510)
                     /locus_tag="VVO74_002152"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU5696094.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            4945..5150
                     /locus_tag="VVO74_002153"
                     /pseudo
     CDS             4945..5150
                     /locus_tag="VVO74_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
BASE COUNT         1791 a         1043 c          919 g         1704 t
ORIGIN      
        1 aaggcattaa atggcccttt ttactatacc cattttagca aaaaagtgag gtaaaatcaa
       61 tgtggatgga agaacttccc aatggaaaat acaaattctt tgaaagatat aaagaccctt
      121 ataccgagaa atggaaaagg gtatctgtaa cccttgattc tggatcaagt agggccaaga
      181 aagaagcgca aaagcttctg gatgagcgat tggaagaaac gctaaagaaa atacaaacta
      241 ctgatatcgt ctatgaacac attttagatg agtggtggac attttatcaa aaagaaatca
      301 aaggaagctc tatcagctct ctgaccagca gtgtgaatga ttttaaaaag gattttgatc
      361 tatctgtgaa agtgagtaac attgatacaa aatacatcca gcgtttttta aatgaccttg
      421 acctttcacg atcaaaatta gagcgatata aattaattct aaatttgtct ctcgattacg
      481 cagtcaatct tgagtatatt gaagacaatc ctgcaagacg tgcgaaactt ccaaagctcg
      541 taaagactat tgaagattta gaaaagacag aaaagaaatt ccttgaagaa gatgagttag
      601 aaagattgct ttctgagcta tatagaacag ataaaacgta taggttagga ttgcttgctg
      661 aatttatggc ttacaacggt tgtcggatag gtgaagctat agcactcaga aaagagaaca
      721 ttgattttga aagcaagact gtcaaaataa acggaacgct agataagact gtaggatatt
      781 ctaaaggatt aaaaacaaca acaaaaacag ctgcaagttt cagaacggtt tccttgtcaa
      841 agagagaact tgaaatatta aaagaattca tctcaataaa tgaactttcg aaaaatacaa
      901 gagaaacctt taaagatctc ggattcatct ttgttactaa gaacggaata cctattcaga
      961 acaactcgtt taatttagcg attcaaaaag taaataatcg acttaaaaac ccaatcaata
     1021 agcatctcac atcgcatata tttcgacata cgctagtgag taggctatca gagaataatg
     1081 tgcctctaaa agcaattatg gctagagtag gtcattctga ctctcgtacc acaaataaaa
     1141 tctatacaca cgttacaaag aagatggatg acaatatact caacttgcta gataatttat
     1201 agttttgccc cttttttgcc ccctatacat aaaaaaagcc tgtcacacaa gctcaaatgc
     1261 ttgatatgac gggctttttc taaattcatt atttaacagc gtctttaaga gctttaccag
     1321 ctttgaatgc tggtacttta gaagctgcaa ttgtcatttc tttaccagtt tgtgggttgc
     1381 gacctttacg ttctgcacgc tcacgaactt caaagttacc aaaaccgatc aattgaactt
     1441 tttcaccagc tgcaagatag tcagctactg ctgcaaatac agcttcaact gctgctgctg
     1501 agtctttctt agtcaattct gtagcttctg ctactttagc gatcaaatct tgtttgtttg
     1561 ccatgttaat gattcctcca aataatttct aattaacaaa tataatcata tcctaaaatc
     1621 ccttttaggt caagttaaaa acgctatttc ttcccatttt atttattttt ttaggagtgg
     1681 taacgtatca aaatagccca agcgttctca cccgtgtgag tttgaataat ggaacccgtt
     1741 tccaaaacag aaattggctt ttcaacataa acttgtaagc tttctttcat ctcttttgcc
     1801 caatcatcac taccagaata tgaaattcca atctctgcta cagcacgttc agaaagcgat
     1861 gttatcaact catctaacca ttttttaaat gttttagttc cacgaccttt aaccattggc
     1921 tgcaattcat ggtctttcat ttgcatgaca acacggatat tgagaaggga gctcaacaag
     1981 ccagttacac ggccaattcg tccacctttg acaagatttt ccaaagttga aacaccaata
     2041 taaagctctg tatggttttt aacctcttct acatgagata aaattgcctc catatcttta
     2101 ccttcttgag ctaacttcgc agcctcaaca acttggaatt tcagggcttg gtcagtgaag
     2161 gaactatcaa caacagtcac atctgcagta gataggctag caccttggcg tgctgcttct
     2221 accgtacccg aaagagcatg ggacatatga atagcaagaa tctggccacc atctttgcat
     2281 aggtcttcaa aaatctcagc aaagacacct acaggtggct gacttgtttt cggaagattc
     2341 ttactttctt gcatcaactg aagaaattta ccttcttctt tcaaatccgc atcagaataa
     2401 acaacattat caatcattac agataatgga acaattgtaa tatctaattg ctttactagt
     2461 tcaggttcaa tagtaacaga tgaatcggtt acaatcttaa tttttgtcat agtatcaatc
     2521 tttctatttt aggattcaga ttggtttcct tacttctaat tatatcaaaa aaaagattaa
     2581 aaatcctaat ggagtcaatc aaattttccg taaaatttga tataatcaac ttataagaaa
     2641 agaggtgtcc tatgattaaa aaaatttacc ccatttttac cattttacta ggtgctgcta
     2701 tttatgcttt tggactgact tattttgtag ttccccatca tctctttgaa ggaggggcga
     2761 caggcattac cctcatcacc ttttatcttt ttaaaatccc tgtttccctc atgaacctgc
     2821 tgattaatat tccccttttc atcctagctt ggaagatctt tggagccaaa tccctctatt
     2881 ctagtttact aggaacctta gctttgtccg cctggttagc tttttttgag catattcccc
     2941 ttcatattga tcttcaaggt gatttactaa tcacagccct tatagcggga atcctattgg
     3001 gaattggcct tggaattatt tttaatgctg gaggtacaac tggcggaact gatattctag
     3061 ctcgtattct caacaaatac actcatatat ccataggaaa actgctcttt atcttagatt
     3121 tttgtattct catgttgatt ctcctaatct tcaaggattt gagattggtt tcctacacgc
     3181 ttttgtttga ttttattgtt tctcgtgtta ttgatttgat tggtgaagga ggatatgccg
     3241 gcaaaggctt tatgattatc acaaaacgtc ctgaccaact tgctaaggcg attaatgatg
     3301 acctcggaag aggtgttact tttatttttg gtcaaggcta ctatagtaaa gaaaatttga
     3361 aaatcatcta ctgtattgtc ggaagaaatg aaattgtgaa aacgaaggaa atgattcatc
     3421 gaatcgatcc tcaagccttt ataactatta cagaagccca tgaaatccta ggagaaggct
     3481 tcacctttga aaaagaataa aaagaggtaa tgtcgtgacc tcaaaagtta gactaaatca
     3541 tctatctttt gggttacaga caacctcttt tttgttttat ttactcaagc tcttaagacc
     3601 aattccgagt tacttcttca tcagccttta actgatccac taattggtca actgagtcaa
     3661 atttggtcat atcacgaatg cgatcaagcc aataaaccat gacggtttcc ccataaatat
     3721 cttgattaaa atcaaaaata ttgacttcaa aacgtgcttc ttctccatca aaggtcacat
     3781 ttttcccgac actagccata gcacgatact tctgtctttg aatctcaaca tcaacgacat
     3841 aaacgccatc tgctggcata taagtacggt ctaaaagcac taaattcgct gtcggataac
     3901 caattgtacg accacgagca ttaccatgaa ctaccatacc tcttgatgga agcggtgccc
     3961 ccaaaagttt tcctgcttct ttcacatttc catctaaaat agcttgacgg atacgagttg
     4021 aactaatctt tcctttctca tcttctacag gtggaacaat gataacttct ccatcaaagt
     4081 aatcctttaa atcttctgct gtttttttgt cagaaccaaa tgtataatca aaacctgcaa
     4141 caataatttt ggcattcata gccttgatat aagttgcaaa gaattcttgt gcagtgagac
     4201 tagcgaattg actactaaaa tcaaggagat ataattcttc tacaccttcg cgctttagtt
     4261 ttctttcacg ttcagcaggg ttcaaaatat gcaaaaacaa atctggatga taaggctcta
     4321 aagcgatctt tggagattca ttaaaggtca taacgacgat aggtaataaa tcctttctcg
     4381 cagccttgtt ggcaacacga aataattctt gatgcccctt atgtatgcca tcaaaatagc
     4441 cgagaacaac gactgaatca gatggtgtgc caatatcttt ttggtttttt ataggaatag
     4501 taataatcat aaaataatta tatcatagcg atagctattt ctggaacaga aaatctgaaa
     4561 tgttgttttt ttcacatgaa gtgtacctgt tttcaaaaag cactttattc tatcgttgct
     4621 taactatgaa ctttgcaata ttcttctcaa aaacttgtag gacatcttca aaattttgca
     4681 aggagtgatt agacttgttc ggtaaccata aagtgtcata ctatgcttat gtatgaaaaa
     4741 gcaatgcaac taactcctga gaactttaaa ttactaattg gtgccgaaaa ggtagaattt
     4801 agaatcgagg tacacctatg gctgtaaaat ttacaaaatg agacaacttg ggcaagatgt
     4861 ttgaagaatt tcctaaactc cctgatttga agcaagtcac tttccctgat gacaaaaaaa
     4921 gccaaagcag taaagaaaaa ctagatgact gctttccaac aacttccatc tagtgtgctt
     4981 cagactgggc tatttttctc tccatctgtt agcttggatt ctcagaccgt ttcagctaaa
     5041 gaatatcttt tcccttatca gaaggaacgg ctcaagccat tcagacaagt gaagggacga
     5101 caagccaata tttgaaacca gatagcagtt cttatagtca attgaaataa aatctgaaga
     5161 aatcgagtag gaaactcaaa tcaattttta acagtgttct attccagatt catactcaat
     5221 gaaaattaaa gtgcaaacta ggaagttagc cgcaggctgt acttgagtac ggcaaggtga
     5281 aactgacgtg gtttgaattt gattttcgaa gagtatcaat ccactataca tattaaaaag
     5341 tatgggtatc aaaataaaaa ggctctataa tatttgtagt gggtaaatcc actatagata
     5401 ttatggagcc tattttgtgt agaaaaaaag tcccatatga cctataatga aaagcga
//
LOCUS       DAVHKZ010000073         5119 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000073 DAVHKZ010000000
VERSION     DAVHKZ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5119
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.073"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(159..239)
                     /locus_tag="VVO74_002154"
                     /pseudo
     CDS             complement(159..239)
                     /locus_tag="VVO74_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            247..609
                     /locus_tag="VVO74_002155"
     CDS             247..609
                     /locus_tag="VVO74_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEU5696095.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            1654..2646
                     /locus_tag="VVO74_002156"
     CDS             1654..2646
                     /locus_tag="VVO74_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU5696096.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            2648..3466
                     /locus_tag="VVO74_002157"
     CDS             2648..3466
                     /locus_tag="VVO74_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU5696097.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            3468..4253
                     /locus_tag="VVO74_002158"
     CDS             3468..4253
                     /locus_tag="VVO74_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5696098.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            4351..4569
                     /locus_tag="VVO74_002159"
     CDS             4351..4569
                     /locus_tag="VVO74_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU5696099.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            4554..4751
                     /locus_tag="VVO74_002160"
     CDS             4554..4751
                     /locus_tag="VVO74_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5696100.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEASNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNPQNPCQILIKKLE"
BASE COUNT         1463 a          859 c         1067 g         1730 t
ORIGIN      
        1 gaaatctagt ggaatgaatc tggaatagtc catcgagctt tctaatactc tttgaaaatc
       61 tcttcaaacc acgtcaacgt cgccttgccg tgtgtatggt tactgacttc gtcagttcta
      121 tccacaacct caaaacagtg ttttgagctg actacgtcag ttctatccat aacttcaaaa
      181 cagtgttttg agcaacctgc ggctagtttc ctagtttgct ctttggtttt cattgagtat
      241 aacagattgt tagaagttgg tttaaatttc ctaatcagtt tgttcacatt taccttcgat
      301 atattatatc ccatagttaa ggttggtcat acagatgatt atagtcatgg agccgtaaaa
      361 cttagtgttt ctttagttga caaagatgcc atgaaaaaaa tatctgtaac tgtaatagga
      421 tattttgaaa taaatataga tgaaaatatc accgatattc tatacgtaaa tggtactgct
      481 attctttatc attatttacg ttctattgtt tcaatagttt cggcaattga tagcagtgaa
      541 gcaatgttgc tacctaccat taatgtttta gagttactag ataaatctca accttttgaa
      601 gaagaataat ttattagctc actaaattga gggtaaggaa aagtaaaatc agtaagaaaa
      661 atgtcttgca ttatacagca accttttggg aatgagtaga tggattgaat aaaattttat
      721 taagagtgga tgatttatct gtagattatt attggacagt tagtcttgaa gtagtctaag
      781 aattaggtta taatcagtag aatccttgct aataatgagg aggttagttt atgtatagta
      841 gactgaatct aaaatagtac gaaacaattg ctaaaacatt tatagaaatt aattttactt
      901 tcccaatcga tttgttctca tcttatttca atccgctata tattatggta tcgaatcttc
      961 atcagaatga taaaattaat caattgatat ctgattacaa acagaatatg aaagcttttt
     1021 atatcactat tgaaaaattt atacgagatg atgaaagcct taagtgttat tttataaagg
     1081 ttatttcaag tcgttccaag gtaacaagtc tagatcagat tgaagctgat aaaacgatac
     1141 aaagaaaata ttcaagtgag ctaaaaaaat ttattggatt ttataatgag attatttgtg
     1201 aggaaaatag tttcctacat gtacgaaaga ggtggtcgag ttggtttagg tagtcgatgc
     1261 gtgagttgat aattctcagg gtatggactt ctttttcatg aatgaggtaa aagagcaggt
     1321 attgtttaga gacaatcatt ctgagcatat tttctggata gagggagtat ccgattttat
     1381 gatcaaagtt aataccgccc tctggtgaga agatgagtag gttggtaatt taaactatta
     1441 aacagaattt ttgattaaaa gtattatttt atgagagaaa tcctaatttc acaatccata
     1501 ggcaaactct tgcatttcgt tttttattgg actataatag gttggtataa agccttttgt
     1561 agtaataaaa tgtagaaggt gtagaaagca aggatttaga atatttgtag ttaaaaacac
     1621 aatgttgcta ttccttacga tagggagata gatatggcaa tgatagaagt ggaacatctt
     1681 cagaaaaatt ttgtgaagac tgttaaggaa ccgggcttga agggggcttt gcgctccttt
     1741 attcatcctg aaaagcagac ctttgaagcg gtcaaggatt tgacctttga ggttccaaaa
     1801 gggcagattt taggatttat cggggcaaat ggtgctggga agtcgacaac cattaaaatg
     1861 ctgacaggaa ttttgaaacc aacatctggt ttttgtcgga ttaacggcaa gattccccag
     1921 gacaatcggc aagattatgt caaagatatt ggcgtagtct ttggacaacg cacccagcta
     1981 tggtgggatt tggctctgca agagacctac actgtcttaa aagagattta tgatgtgcca
     2041 aactcgctct ttcataagcg catggacttt ttgaatgaag tcttggattt gaaggacttt
     2101 atcaaggatc ccgtgcggac tctttcactg ggacaacgga tgcgggcgga tattgcggcc
     2161 tccttgctcc acaatcccaa ggttcttttt ttagatgagc cgaccattgg tttggacgtt
     2221 tcggttaagg ataatattcg tcgggcaatt actcagatca atcaagagga agaaactacc
     2281 attcttttga ccactcacga tttgagtgat attgagcaac tttgtgatcg gattttcatg
     2341 attgacaagg ggcaagagat ttttgatgga acggtgagcc aactcaagga gacctttggt
     2401 aagatgaaga ctctctcttt tgaactgcta ccaggtcaaa gtcatctcgt ctctcactat
     2461 gaaggtctgt ctgatatgac cattgataga caaggaaaca gcctcaacat tgaatttgat
     2521 agttctcgct accagtcagc tgacattatc aagcaaaccc tgtctgattt tgaaatccgc
     2581 gatttgaaga tggtggatac ggatattgag gatattatcc gtcgcttcta ccgaaaggag
     2641 ctctaggatg atcaaattgt ggagacgtta taaacccttt atcaatgcag gggttcagga
     2701 gttgattact taccgagtca actttattct ctatcggatt ggcgatgtca tgggggcttt
     2761 tgtggccttt tatctctgga aggctgtctt tgattcttcg caagagtctt tgattcaggg
     2821 cttcagtatg gcggatatca ccctctacat catcatgagt tttgtgacca atcttctgac
     2881 tagatccgat tcgtccttta tgattgggga ggaggtcaag gatggctcca ttatcatgcg
     2941 tttgttgcga ccagtgcatt ttgcggcctc ctatcttttc accgagcttg gttccaagtg
     3001 gttgattttt atcagcgttg gccttccatt tttaagtgtc attgtcttga tgaaaatcat
     3061 atcgggtcaa ggtattgtag aggtgctagg attaactgtc ctttatcttt ttagcttaac
     3121 gctcgcctat ctgattaact ttttctttaa tatttgcttt ggattttcag cctttgtgtt
     3181 taaaaatctt tggggttcca acctacttaa gacttccata gtggctttta tgtcggggag
     3241 tttgattccc ttggcattct ttccaaaggt tgtttcagat attctttcct ttttgccttt
     3301 ttcatccttg atttatactc cagttatgat cattgttgga aaatacgatg ccagtcagat
     3361 tcttcaggca ctccttttgc agttcttctg gctcttagtg atggtgggat tgtctcagtt
     3421 gatttggaaa cgggtccagt cctttatcac cattcaagga ggttagtatg aaaaaatatc
     3481 aacgaatgca tctgattttt atcagacaat acatcaaaca aatcatggaa tataaggtgg
     3541 attttgtggt tggtgtcttg ggagtctttc tggctcaagg cttgaatctc ttgtttctca
     3601 atgtcatctt tcaacatatt ccattcctag aaggctggac ctttcaagag atagctttca
     3661 tttatggatt ttccttgatt cccaagggaa tggaccatct cttttttgac aatctctggg
     3721 cactagggca acgcctagtc cgaaaagggg agtttgacaa gtatttgact cgtcccatca
     3781 atcctctctt tcacatccta gttgaaacct ttcagattga tgccttgggt gaactcttag
     3841 tcggtggtat tttattggga acaacagtga ccagcattgt ttggactctt ccaaaattcc
     3901 tgcttttcct agtttgtatt ccttttgcga ccttgattta tacttctctt aaaatcgcaa
     3961 cagccagtat cgccttttgg actaagcagt caggcgccat gatttacatc ttctatatgt
     4021 tcaatgactt tgctaagtat ccgatttcta tttacaattc tcttcttcgt tggttgatta
     4081 gctttatcgt gcctttcgcc tttacagcct actatccagc tagctatttc ttacaggaaa
     4141 aggatgtgtt ctttaacgta ggaggtttga tgttgatttc tctggttttc tttgttattt
     4201 cccttaaact ttgggataag ggcttagatt cctacgaaag tgcgggttcg taaaagctaa
     4261 agtaagacta aaatcaagaa aggaacttat gatgtttgta attgaagaag tcaaggatga
     4321 aaatcaaaaa aggcagttct cgctgaggtt ttgaaggatt tgccagaatg gtttggaatc
     4381 ccagaaagca cacaagccta tatagaagga accacgacac tgcaagtttg gaccgcctat
     4441 caggagagtg atttgactgg atttgtaagg ttatcctatt cgagtgaaga ttgtgcagag
     4501 attgattgtc tcggcgtaaa aaagcttatc aaggtagaaa aattgggagc caattgcttg
     4561 ctactttaga gagtgaagct cgtaaaaaag ttggttatct gcaggtcaaa acagtggcag
     4621 aagcttctaa taaagattat gatcgaacaa atgactttta tcgaggtctt ggctttaaaa
     4681 agttagagat tttttctcag ctatggaatc cgcaaaatcc ttgtcagatt ttgattaaaa
     4741 agcttgaata atattacttg acatctattc tcagagtgcc atactgtaag tgtaatcgcc
     4801 gatttagctc agttggtaga gcaaggcact cgtaaagcct aggttatagg tagataaacg
     4861 actgaggagt tgaaaaaata gataggtaga agataaccgt taagccttat tcttagcggt
     4921 tatttatatt atttaatagc gctgatattt catcaattat gcctgttttc gtgtttctgg
     4981 tagttgttca agtttattgc tactattttt gatggtatga atgtgcttat aatgtatccc
     5041 ggttaacgaa agttttggac ttatactctt cgaaaatctc ttcaaaccac gtcaacgtcg
     5101 ccttgccgtg cgtatggtt
//
LOCUS       DAVHKZ010000074         4757 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000074 DAVHKZ010000000
VERSION     DAVHKZ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4757
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.074"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            1..613
                     /locus_tag="VVO74_002161"
                     /pseudo
     CDS             1..613
                     /locus_tag="VVO74_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(606..773)
                     /locus_tag="VVO74_002162"
     CDS             complement(606..773)
                     /locus_tag="VVO74_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEU5696101.1"
                     /translation="MKKRILSAGLTFTSDLLLAACGQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(938..2545)
                     /locus_tag="VVO74_002163"
     CDS             complement(938..2545)
                     /locus_tag="VVO74_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU5696102.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKELLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2698..4182
                     /locus_tag="VVO74_002164"
     CDS             2698..4182
                     /locus_tag="VVO74_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU5696103.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPGGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMSERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            4277..>4757
                     /locus_tag="VVO74_002165"
     CDS             4277..>4757
                     /locus_tag="VVO74_002165"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU5696104.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1397 a         1068 c          909 g         1383 t
ORIGIN      
        1 tagcttctga atttgcctgt catccaacta ccatccacta tgcgctcaaa gctatgggct
       61 acactcgaaa aaaagaacca cacctactat gaacaagacc cagaaaaagt agccttattt
      121 cttaagaatt ttaatagttt aaagcaccta gcacctgttt agattgatga aacaggattc
      181 gatacttatt ttcatcgaga atatggtcgc tcattaaaag gtcagttaag aagaggtaaa
      241 gtatctggaa gaagatatca gaggatttct ttggttgcag gtctaacaaa tgaatggtga
      301 gttaatcgct ccaatgactt acgaagagat gatgacgagc gacttttttg aagcttggtt
      361 tcagaagttt ctcttaccaa cattaaccac accatcggtt attattatgg ataatgcaag
      421 attccataga atggggaagc tagaactctt gtgtgaagag tttgggcata aacttttacc
      481 tcttcctccc tactcgcctg agtacaatcc tattgagaaa acatgggctc atatcaaaaa
      541 gcacctcaaa aaggtattac caagttgcaa taccttttat gaggctcttt tgtcctgttc
      601 ttgtttcaat tgactatatt atcagcgtaa tagtctaata gatagttaaa tgtagttgga
      661 tttccactaa aggttgatga gtaagttttt gtatctgaac ctgattggcc gcaagcagct
      721 aaaagcaaat cagatgtaaa agtcaggcct gcactaagga tacgcttctt tatgttcgtc
      781 ttctttctcc ttaatagtgg gaatttgtaa agttaattga atttcgagaa tgaaggttta
      841 taaaccttgg ttataaaaaa caaaggattt ctgcctttta tacagtcctc ccttgttttt
      901 atacgatttc aattttaaat ttttctgcaa aaaatattta tagtaattcc acacagaaag
      961 catcccatgg aactaagatt tgtttttcaa agacttcttg agctagggtg ttttcaatca
     1021 agacagattt gacttttcct tctactgtca agtcttgctc ttcattagac aagttagcca
     1081 caactaggaa gcgacggtcg ccatccttac gtatataagc aaagacctta tcagccgtat
     1141 caagcaattc aaagtcagct cgaattagcc agctattctc cttgcgaatt tggaccagtt
     1201 tctgataggt atagaaaata gaatctggat ttgccagcgc ttcttggacg ttgatcatct
     1261 cgtaatttgg attaaccgcc aaccaaggtt gacctgttga gaaaccagcg tttttgctct
     1321 cgtcccattg cataggggta cgggcattgt cacgtccaat aacacggata ctgtccatga
     1381 tttcttcaat cggaacacct ttttcaagag cctcacgcgc atagttgagg gattcaatat
     1441 cttctacttg atccagtgtt tcaaacggat agttggtcat cccaatctcc tcaccttggt
     1501 agatataagg agttcctctc atgagatgaa gtaagattgc aaaggctttg gcagattttt
     1561 cgcggtattc ttggtcattt ccccagattg agacaatacg agggaggtca tggttgttcc
     1621 agaagaggga attccagccg tcctcaactc ctaactctgt ctgccatttg ttgaagattt
     1681 cttttaactt agcgatattc agctcttttt gatagtgcca tttaggctga ccttcctgat
     1741 actgaagacc gatatgttca aactggaaga ccatagacaa ttcttgcccc tttggatcag
     1801 agtagagctt ggcaatctct ggcgttgctc cccaagtctc ccctactgtc aagagctcct
     1861 tatctccaaa ggtcgcctga ttcatttcct tgagataggg atggagcata ggaccattat
     1921 tgactacctt ctcgtcagga attttgccaa tcatgtcaat aacatccata cggaaaccac
     1981 caataccttt atcaatccag aagttcatca tctcataaat tttctggcga agtttttcat
     2041 tttcccagtt gagatccggc tgtttcttgc tgaaaaagtg gagatagtat tgacctgact
     2101 tttcatcgta ttcccaagca gacccactaa agatagaatc taggtcattg ggttcatcgc
     2161 gccagatata gtagtctcgc tcagggctgt cagtattttc acaggcttcg acaaaccaag
     2221 catgctcatc cgaggtatga ttgaccacca agtccatgat gatacggata tcacgcttct
     2281 tagcttctgc aatcagctga tccatgtcct ccatggttcc aaaaatagcc gcaatcgctt
     2341 gataatcagc aatatcgtag ccattatcat ccatagggct gtcataaacg ggagaaagcc
     2401 aaatcgctgt gattcctaac ttagctagat agtccaactt actggtaata cctggcaaat
     2461 caccaactcc atctccatta ctatccataa aactctttgg atagacttga tagactacgg
     2521 cattatgcca ccatttttct tgcatctgtt tacctcatta ttttaataat ctatagtcta
     2581 tgatagcact ttttaaaatt ttgtgcaagc gtttgcttaa tctttttaat ttctttttta
     2641 gctccgtagt ttcctaactt ccaatttttt attataatag agtccagagg taaaaaaatg
     2701 aaaaaacaag cttttagttc tgaacagtat ttgaatttac aacgcgacca tattttggag
     2761 cgcattaacc aatttgacgg caagctctac ttagagtttg gcggtaaaat gttagaagat
     2821 ttccacgctg ctcgtgtcct tcctggttat gaacctgaca acaaaatcaa gctcttgcaa
     2881 gaattgaaag agcaggttga ggttgtgatt gccattaatg ctagcaacat tgaacattcc
     2941 aaagcacgtg gcgacttagg catttcttat gaccaagaag ttcttcgttt gattgacaaa
     3001 ttcaatgaat tagggatttt tgttggttcc gttgtcatta cacaatacgc tggccaaccc
     3061 gctgcagatg ccttccgcaa ccaacttgag aaaaacggaa ttgattctta tcttcattat
     3121 ccaatcaaag gatatcctac ggatatggat cacatcattt ccccaggagg catgggcaaa
     3181 aacgactaca tcaaaaccag tcgcaacttg attgtcgtaa ccgctcctgg acccggttct
     3241 ggaaaattgg caacgtgtat gtccaatatg taccacgacc aaatcaatgg catcaaatct
     3301 ggctacgcta aatttgaaac cttccctgtt tggaatcttc cccttcatca tccagttaac
     3361 ttggcttatg aagctgccac agctgacctt gatgatgtca acatgattga ccccttccat
     3421 cttcaaacct atggagaaac cactgtcaac tacaaccgtg atatcgaaat cttcccagtg
     3481 ctcaaacgca tgtcggaacg tattctcgga aaatcaccat acgcttcacc gacagatatg
     3541 ggtgtcaaca tggttggttt cgctattaca gatgacgagg ccgctgtcga agcttctaaa
     3601 caagaaatca tccgccgtta ctatcaaaca gttcttgact tcaaagctga aaaagttggc
     3661 gaagctgccg tcaagaaaat tgagttgctc atgaacgacc tcggtatcac acctgcagac
     3721 cgtaaggttg ctgtcgttgc gcgccaaaaa gcagaagaaa ctggtggacc agccctagcc
     3781 tttgaattgc caaatgggga aatcgtcact ggtaagaact cagaactctt tggtcctaca
     3841 gccgctgcct tgatcaacgc catcaaaaaa tcagctgaca tcgctaaaga agtaaaacta
     3901 atcgaacctg aagttgttaa gccaatccaa ggtcttaaaa tcgatcatct cggtagccgc
     3961 aatccacgcc ttcattcaaa tgaaatcctg attgcacttg ctatcacagc tacagaaaat
     4021 cctgatgctg cccgcgctat ggaagaacta ggcaacctca aaggaagcga agcccactca
     4081 accatcatct tgactgatga agacaagaat gtccttcgta aactgggtat caacgtaacc
     4141 tttgacccat actaccaata cgaccgctta tatcgtaagt aaagatttca acctctctag
     4201 cctcggagag gttttctctc tgtctcagga acaaccttta tgatataatg agagaagaaa
     4261 actgaaagga tttaccatgt caaaagaagt tattgtcgaa agttttgaac ttgaccacac
     4321 cattgtcaaa gcaccctatg ttcgcttgat tggggaagaa acaggaccaa aaggagacat
     4381 catctccaat tatgatattc gcttggtgca accaaacgaa gactctatcc ctactgccgg
     4441 ccttcacact atcgagcacc tcttagccaa actcatccgt acccgcattg acggcatgat
     4501 tgactgttca ccatttggtt gccgcacagg cttccacatg attatgtggg gacgtcacac
     4561 cagtgctaaa atcgcagctg ttatcaagga ttcgctcaag gaaatcgctg aaactactac
     4621 ttgggaagat gtcccaggga caaccatcga atcttgcgga aactacaagg accacagcct
     4681 cttctctgct aaagaatggg caaaactcat cttggaacaa gggatttcag atgatgcctt
     4741 tgaacgtcat gtgattt
//
LOCUS       DAVHKZ010000075         4489 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000075 DAVHKZ010000000
VERSION     DAVHKZ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4489
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.075"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..736)
                     /locus_tag="VVO74_002166"
     CDS             complement(<1..736)
                     /locus_tag="VVO74_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU5696105.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYL"
     gene            complement(736..2301)
                     /locus_tag="VVO74_002167"
     CDS             complement(736..2301)
                     /locus_tag="VVO74_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU5696106.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            2439..4328
                     /locus_tag="VVO74_002168"
     CDS             2439..4328
                     /locus_tag="VVO74_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU5696107.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWSRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKTLQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
BASE COUNT         1241 a          830 c         1032 g         1386 t
ORIGIN      
        1 tgagataacg ttgaagaaat tcttttgtac ggtcttcttt aggattagtg aagaggtctt
       61 ctggtttacc ttcttcagca atcacaccct tatccataaa gataacacgg tgagagacat
      121 cacgggcaaa ttccatttca tgggttacga caatcatggt caagccttcc tgagccagat
      181 cttgcatgat tttgaggacc tctccaacca tttctggatc gagagctgat gttggttcat
      241 caaagagaat ggcgtcagga ttcattgaaa gggcacgagc gatggccaca cgttgttttt
      301 gaccacctga gagttgtttg ggtctcgctt gccagtagcg ttctcccatg ccgacctttt
      361 ccaggttttc tttggcaatt tcttcagctt ctgtgcgttc gcgtttaagg acagttgtct
      421 gagcgacgat tgtgttttca agaacgttga gattttcaaa gaggttaaag gattggaaaa
      481 ccatccctaa cttttcacgg tattgcgtga ggtcatagcc tttttcgagg acgttttgtc
      541 catgataaag gatttgtcca tcagttggcg tttcaagtag gttaatggag cgtaggaagg
      601 ttgatttccc acttccagag cttccgatga tagaaataac ttctcccttg tggacagtga
      661 gagaaatgtc ttttagcact tcgttttgtc cataggattt tttgaggtgt ttaatttcaa
      721 ggattgcttg tgtcattatt tcaaatcctc cgtttgcatt tggttagcac ctgtagtgta
      781 ggtatccatg tccattctgc gctcgataaa gcgtaggata cgtgttacgg tgaaggtgag
      841 gacaaagtaa atcacggcga tgattgtaaa tgtctggaag tattgatagg tttgtgttgc
      901 cacggtattt cctgagaaat aaagttcgac aacagagata acgttcaata cagatgtatc
      961 tttgatattg atgacaaatt cattaccagt tgcaggtagg atgttacgga ctacctgagg
     1021 taggacaatc ttacgcatgg tctggttatg ggtcatacca agagcagtcg cagcttcaaa
     1081 ttgtcccttg tcaactgcta ggataccacc acggacgatt tcagtcatgt aggcaccggt
     1141 attgattgaa acgatgaaga tagcagccag tgtacggtca aggttgatcc cgaaagcttg
     1201 ggcagttcca tagtagataa ccatcgattg aacaatcatt ggcgtaccac ggaaaatttc
     1261 aatgtagaca ttgagaaccc agccgactag tttttgaagg ccataaatgg ctttgttttc
     1321 agagagagga gcagtacgga agacaccaat ggcaagtcca ataatgagac ctatgatggt
     1381 tccgacgata gagattaaaa gagtgatacc agcaccacgc aagagttgtt gccagttttc
     1441 agaaagaatt ttagcgactt ggctaaagaa actactgcta gtctcttcag ttgttgtagc
     1501 ttcggcaggt tgttccttga tcatacgatc catcagggca acttggtcgt cctttgaaat
     1561 ggtttcaatg ctggcattga tttggctaat acgattgtca tttttacgaa gcccgatagc
     1621 gatagctgta tcttcttccc cagttttgaa accaggttct acttgaatca tcttgaactt
     1681 agagttcgca gcttcagcag tcagtgcttc tggacgttca gaaacataag catcaatgac
     1741 accagcctca agagcttgtc gcatttgagc gaagtctccc atggctgttt cttttttagc
     1801 acctgggatt tgtgcaatca agtcgtagag gtagacccct tgttgagaag tgatttttgc
     1861 accgttaaag tcatccaaag atttagcact tgcgtaggca gaatcttttt tgacaagcaa
     1921 aactggttcg ctagtgtagt aactgctcga aaaggcaatt tcttgtttgc gttctgcagt
     1981 tggactcata cctgcgataa tcatgtcaat cttaccagaa gtaagggcag gaactagacc
     2041 ttcccacttg gttttaacaa ccaaaggttc tttacctaag tccttagcga ttttcttggc
     2101 gatttgaaca tcgtatccgt tggcatactg attggtccca tcgattttga cagctccgtt
     2161 gctatcatca tcctgggtcc agttaaaggg agcatatgct gcttccatcc cgatgcgtaa
     2221 atattcatcg gcttgagcaa cattgacaag tcctagcatc agcaagagac ttgtgaaaat
     2281 agataagtat atttttctca tgatttctcc tattctgatc tattaaaaaa taactgtctc
     2341 ctattttatc gaaaaatgcg taatttttca acataagtaa gcctttactt acgaaaaaat
     2401 gctataatga taagaaagat aaaaaggggg cttagttgat gaaaaaaact tttttcttac
     2461 tggtgttagg cttgttttgc cttcttccac tctctgtttt tgccattgat ttcaagataa
     2521 actcttatca aggggatttg tatattcatg cagataatac ggcagagttt agacagaaga
     2581 tagtttacca gtttgaggag gactttaagg gccaaatcgt gggacttgga cgtgctggta
     2641 agatgcctag cgggtttgac attgaccctc atccaaaggt tcaggctgcg aaaaacggtg
     2701 cagaactagc agatgtgact agcgaagtaa cagaagaagc ggatggttat actgtgagag
     2761 tctataatcc aggtcaggag ggcgacatag ttgaagttga cctcgtctgg aacttaaaaa
     2821 atttactttt cctttatgat gatatcgctg aattaaattg gcaacctctg acagatagtt
     2881 cagagtctat tgaaaagttt gaatttcatg taaggggaga caagggggct gaaaaactct
     2941 ttttccatac agggaaactt tttagagagg gaacgattga aaagagtaac cttgattata
     3001 ctatccgttt agacaatctt ccggctaagc gtggagttga gttgcatgcc tattggtctc
     3061 ggaccgattt tgctagcgct agggatcagg gcttgaaagg gaatcgttta gaagagttta
     3121 ataagataga agactcgatt gttagagaaa aagatcagag taaacaactc gttacttggg
     3181 tcctcccttc gatcctttcc atctccttgt tattgagtgt ctgcttctat tttatttata
     3241 gaagaaagac cactccttca gtcaaatatg ccaaaaatca tcgtctctat gaaccaccaa
     3301 tggaattaga gcctatggtt ttatcagaag cagtctactc gacctccttg gaggaagtga
     3361 gtcccttggt caagggagct ggaaaattca cctttgatca acttattcaa gctaccttgc
     3421 tagatgtgat agaccgtggg aatgtctcta ttatttcaga aggagatgca gttggcttga
     3481 gattggtgaa agaagatggt ttgtcaagat ttgagagaga ctgtctaaat ctagcctttt
     3541 caggcaaaaa agaagccact ctttccaatt tgtttgcgga ttacaaggta tctgatagtc
     3601 tttatcgtag agccaaagtt tctgatgaaa aacggattca agcaagaggg cttcaactca
     3661 aatcttcttt tgaagaggta ttgaaccaga tgcaagaagg agtgagaaaa cgagtttcct
     3721 tctgggggct cccagattac tatcgtcctt taactggttt ggaaaagact ttgcaagtgg
     3781 gtatgggtgt cttgactatc ttgcccctat ttatcggatt tggtttgttc ttgtacagtt
     3841 tagacgttca tggctatctt tacctccctt tgccaatact tggttttcta gggttagttt
     3901 tgtctgtttt ctattattgg aagcttcgac tagataatcg tgatggtgtt ctaaatgaag
     3961 cgggagctga ggtctactat ctctggacca gttttgaaaa tatgttacgt gagattgcac
     4021 gactggataa ggctgaattg gaaagtattg ttgtttggaa tcgtctcttg gtctatgcaa
     4081 ccttatttgg ctatgcggac aaggttagtc atttgatgaa ggttcatcag attcaagttg
     4141 aaaatccaga tatcaatctc tatgtagctt atggctggca cagtatgttt tatcattcaa
     4201 gcgcgcaaat gagccattat gctagtgtcg caaatacagc aagtacctac tccgtatctt
     4261 ctggaagtgg aagttctggc ggtggcttct ctggaggcgg aggtggcggc agtatcggag
     4321 ccttttaaag agagctacca tagactgaaa aagtatgata taatggaaga tagaagaaag
     4381 acaaactata agaaaagtca atagttttat ctaaactatt tcttatttca atttgatgat
     4441 ttggcgatga ttttagagca cggcaaaaag cccttgaaaa agtccattt
//
LOCUS       DAVHKZ010000076         4305 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000076 DAVHKZ010000000
VERSION     DAVHKZ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4305
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.076"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(1..618)
                     /locus_tag="VVO74_002169"
                     /pseudo
     CDS             complement(1..618)
                     /locus_tag="VVO74_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(727..1245)
                     /locus_tag="VVO74_002170"
     CDS             complement(727..1245)
                     /locus_tag="VVO74_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEU5696108.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1472..2341)
                     /gene="rsmI"
                     /locus_tag="VVO74_002171"
     CDS             complement(1472..2341)
                     /gene="rsmI"
                     /locus_tag="VVO74_002171"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU5696109.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2344..2661)
                     /gene="yabA"
                     /locus_tag="VVO74_002172"
     CDS             complement(2344..2661)
                     /gene="yabA"
                     /locus_tag="VVO74_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU5696110.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2701..3591)
                     /locus_tag="VVO74_002173"
     CDS             complement(2701..3591)
                     /locus_tag="VVO74_002173"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU5696111.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3588..4226)
                     /locus_tag="VVO74_002174"
     CDS             complement(3588..4226)
                     /locus_tag="VVO74_002174"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU5696112.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLELHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMDLAK"
BASE COUNT         1181 a          984 c          696 g         1444 t
ORIGIN      
        1 tgtaattctc aagctgtgag ttcattatga tttgtaaatc cgatatatct tcagcagcta
       61 aaaacacatt ttgaaatgtt ccaagtccgt tttcaccaaa actatattct ctcttactat
      121 acttactctt attattctct atatagttag agtcaaggtt cttaacctct tgaagttcat
      181 tttctttact tctgaggtta aaatctttta cttctgaagt taagtttttt gacttctgta
      241 agtcattttc ttttacctga aatatactca taaagtcttt aacataaatg atgttcggct
      301 taccaagtcc aagccttact ctttcgatca gtcctattcc ttttttacat caagctcatc
      361 taatgttttt atggcagttg gctttgagat atttcttctt ttcataattt cttcgacagt
      421 aaaatagata aatactctgc cttccttgtc tatccagtta ttcttaaatg acattcctgt
      481 ctgtttaaga agtatggaat aaaggataat tgcttctgct gataagcccc gaaattcttc
      541 tctatcaact aatatctccg gtacttttaa gaagttaaat ctttccgctt ctctgttata
      601 aaaatattca aagtccatgc aagatcacct cccttcttaa aaatttgcaa agaaaaagac
      661 gatagttttt cttctatcgc ctttggtaac catttttatg aaatttttta aagttaaaaa
      721 tataatttat aatactatct tcttccattt tctgatttta gttctgaaag ttccaaaagg
      781 tgcaaccgta tttacatgaa taaacttata cacttcccaa gtcgctgttt tagtcgcttc
      841 atcagcccac tttctcatat gcggttcaaa taattcttcc tcactcaacg aatcaatcat
      901 tgcagagata gaattaatat tttcatttaa ttttgctttc aactcttgca gagataaatg
      961 agcgtaggta tctgtgaacc actgatataa ttcaccaagt tgattccatt taaatttatc
     1021 cgatggtgtt tttacttgaa gcccctttct ttcatcttct tcccatttaa gaaccaagtt
     1081 ggtccaacca acctgataag caaggttttc tgctggagtt ctgtcaactt catcagctct
     1141 cttatctttt aaattttctg gaatattatc aaattctaaa atatatttct caaatgtttt
     1201 ctctatctca gcttttagtt cttctttatt ttcgtatgtt cgcaaaaaat caccttcttt
     1261 ctgatttatc aatcctttga tttaaaatga ccttattttt ctatttatac cttctaagaa
     1321 cgctataact gctgctccaa ccatcggtat tccgtatggg cttaataaaa aacttaatac
     1381 caaagcttct ataccaagtg atacatcttt atattatcat cactaattaa gttaaacaga
     1441 aacagacaga attattacat cctgtctccc tttattgttt ttcttcccag tcgtggtagg
     1501 cagcgtagag ctgactttta ttccactggt aaatcttagc gacttccttg atagcttggt
     1561 ttttcttcac accttgctgg atgcgggttt gaatttctac gaacaagtct tcctcgtcct
     1621 tttcctccac accctgactg gcaccctcaa caatgagaag acattcgccc ttgagtggcg
     1681 tttcagcaat gctttctaat aactcagaga tagtacctcg ttggtattct tcatagattt
     1741 tggtcaattc cctgaccaag acaacggagc ggtcaccgta gacttctaac atattttcca
     1801 acgtgtctgc tacacgatga ggtgattcat aaaaaatctg tgtttcagga taatcttttt
     1861 tcaagccaaa aaattgcttc tgctgacctg attttctcgg taaaaaaccg taaaagatat
     1921 gtggctgtgg cgctaaacca ctggcaatca aggcagaaat tcctgcagag gcacctggaa
     1981 ctgtcacaac tgcaatttct tcctcaatag ctgccttaac taaatcatga ccagggtctg
     2041 aaatgctagg caaaccggca tcagagacct gagcaatact ttgccctgct ttcaagaaac
     2101 caatcaaatc aggaattttt tccttggcat tgtgctcatg aaaactgatc tgcttggtgg
     2161 aaatgtcaaa atgcttgagc aaaagccctg tattgcgcgt atcctcagca gcaatccagt
     2221 ccacttcttt caaggtctgg atagcacgaa aagtcatatc atctagattg ccaatcggcg
     2281 ttgccactag atacagcttg ccatagggag actgcccctt aaaacttttt tgaatttgca
     2341 tgcttactcc ctgtataaca actcatcaca gaacatacat tcttcgtcct gctctcgacg
     2401 ttgtccataa aaatcattac atacgtgaaa tccatcacgg taaatacgac ggacactttc
     2461 gcgaacatgc ttggccttga cgggagcgtc tgcttccacc tcacccaagc gttctcgcaa
     2521 cttactattt tccaagcgaa gagctgtatt ttcttctacc aagctcttga gatttttctt
     2581 gatggcttcc acatcggcta aggttaccaa taattgttgg gaaaaatcat ccagcgcgtc
     2641 aaataattct tttttgtcca taaaacagcc ctttcctttc tttatcattc atttttgagt
     2701 ttatatttct ttcaagacca gatattccat ggcattttga aagctgacat tagcttgcca
     2761 catttttcta gcttctagta aatcttgtag aatcactctt actcttacct gcaagaggtc
     2821 ctgcccacag agaacttcaa gaatccgtaa aacctgatcc tgtttttcct tatcatctgc
     2881 caagttggct aatttggcaa cctgtagata actttctttt ttcttagcta ctaaccaagt
     2941 cagcaggcgt tcactttcat cgaccaaggt ccaaaaactt gcctgattag ccaacttttc
     3001 tgcttcagct cgcgattgac taaacttagc taaaagagtc gcttttttct taacaagtcc
     3061 catttgttct aagagtaaga taagtttttc ttcttgcttt ttaaagtgga agatctgagt
     3121 ccgacttcgg attgtcggta acatcttttc ctcatcgcta gtcaagaaga aaatataaac
     3181 ttcactctgg ggttcttcga tgaccttgag cagagaattg gctgcgttgg gatgcatttt
     3241 atccgcttgc tcgataataa agacctgttg ctggctttca atccctgctt gagaaaactg
     3301 tcccaccaat tcccgaatgc gttctgtctt gatgacctga ttgactggct taatcaaggt
     3361 gacatctgga aactcttcct gttcaatcag cttgcaactt cggcatttct cacatggtaa
     3421 gacgccaact ttatccgtac aaaagaggct cttagctaaa aattgcgcca tttccaagct
     3481 tccaaagaaa cctgaaaaga gataggcgtg attgagctgg tcttgttcta agatacggac
     3541 aaaacggtca aactgagctg gttgccaagc ctttagttga tcttgtttca tttggccaag
     3601 tccattccgt caaacaagac agccttggta gtttccacaa cttgctccaa agggagacta
     3661 gcatcaatct tgacaatgcg atttccttct ttttccagga gagaaaggta gccttgacgg
     3721 actttcttgt gcaattccaa accttccaag tccagacgat tgacctcgcg gtcactattc
     3781 gcagcaatgc gagccagccc ttcttccacc tcgatgtcaa aatagagtgt caaatcgggt
     3841 ttgaggccat ctgtcgcaaa ctgattgagc cagtcaatgg cttcaatatc taagccacga
     3901 ccaaatccct gataggcaac agaactatcg ataaaacgat ccatgatgac caacttgcca
     3961 gcttcaaggg ctggaagaac tttttccacc aaatgctgtc tgcgactggc aatatagaga
     4021 agtagctctg ttttagcatc catctgagta tgacttggat ccaaaatcac ttcccgaatc
     4081 ttctccccaa tcaagactcc gccaggttca cgggtcgtca gcacctttac tcctttttcc
     4141 tctaaaattg gtagcagagc ctctaaaaca ctggtcttgc ctgctccctc tggtccctca
     4201 agagagacta aaaatccttt tgacatgtct aactcatttc ttttttacta cttctattct
     4261 atcaaaaaaa taggggtttg tgacaatctt tttgtcttct cattt
//
LOCUS       DAVHKZ010000077         4205 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000077 DAVHKZ010000000
VERSION     DAVHKZ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4205
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.077"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            371..598
                     /locus_tag="VVO74_002175"
     CDS             371..598
                     /locus_tag="VVO74_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696113.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /gene="nanA"
                     /locus_tag="VVO74_002176"
     CDS             886..3783
                     /gene="nanA"
                     /locus_tag="VVO74_002176"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEU5696114.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTPE
                     LPKGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPKRENGMVHLARVEENGELTWIKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1445 a          690 c          904 g         1166 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaataaggta taataaattt
      241 actaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acaccagaac tacctaaagg ccgagtgcgc
     1561 ctctacgtaa acggggtatt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt acaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtgaccaat tactaggcaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttagatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 agacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcataatgg aaaagaatac attatcctca gcaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggctcgt gtcgaagaaa atggtgagtt gacttggatc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga ctttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 ttcgactcag aagtattggt caacaaggct ccaacccttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttat ttgcagtaga taaggaagat
     3421 atcggacagg aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtacagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact
     3901 actttcagag tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
     3961 atcaggaaag tcaaattaat ttatagaaaa attttagcag tcaaggtgta ctgttataga
     4021 ttcaatatat tatgcgacta ttaaccttgt cttctcctaa aattgacttt cttgttttct
     4081 tatcttgtcc actcgaaaca agtattgtaa gaatttgatt atttttgaaa gtacttttaa
     4141 tatacttgat atagttaaaa aagatttgaa actaaattcc aaattagaaa aagacttgaa
     4201 atact
//
LOCUS       DAVHKZ010000078         3285 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000078 DAVHKZ010000000
VERSION     DAVHKZ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3285
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.078"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            607..1953
                     /gene="gdhA"
                     /locus_tag="VVO74_002177"
     CDS             607..1953
                     /gene="gdhA"
                     /locus_tag="VVO74_002177"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU5696115.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGHLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2459..2629)
                     /locus_tag="VVO74_002178"
     CDS             complement(2459..2629)
                     /locus_tag="VVO74_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696116.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2642..3220)
                     /locus_tag="VVO74_002179"
                     /pseudo
     CDS             complement(2642..3220)
                     /locus_tag="VVO74_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
BASE COUNT         1039 a          606 c          540 g         1100 t
ORIGIN      
        1 aaatcgttgt ttgattacag tctaaaagct ctataatctc tttataagat ttgcccatca
       61 gacgaaatat agtagattga aactagaata gtacacctct acttctaaaa cattgttaga
      121 aatcgatttg actgtcctga tcgatttgcc ctgttcttgt ttcgttttac tatagaacga
      181 tttgaaggcg tttatgatat ttagctgtac gagagtcttt taaaagtgtt ttgatggctt
      241 ggatttcttc tttagttgat ttcatatcac tattatataa tgctttttga ttttagtctg
      301 gtataaatat tgctttcctc caaaatggtc ataattttac tagcaaatct aacatatcac
      361 ggataaatta acaagtgatt tctgaattgc taaacatttt cttttcttat agcataccat
      421 actttaagat tttgtctttg agaaagatat ttccaagaaa aacgttcgtt tttttatcta
      481 ttttcaaaaa aaaccaaaaa ctgaattgaa agaattttta gaaaatttct gttttttctt
      541 tacagtgaaa aaaaattctg ctataatgtc ttatgtaata aaatatgaca ataaaaggag
      601 aacgatatga catctgctaa agaatatatc caaagcgtgt ttgaaactgt aaaagctcgt
      661 aacgggcacg aggctgaatt cctccaagct gttgaagaat ttttcaacac tttggaacct
      721 gtatttgaaa aacaccctga gtatatcgaa gaaaatatct tggcacgtat tactgagcct
      781 gagcgcgtga tttctttccg tgttccttgg gttgaccgtg atggaaaagt tcaagtaaac
      841 cgcggctacc gtgttcaatt caactcagct gttggaccat ataaaggcgg acttcgtttc
      901 cacccaactg taaaccaagg gattttgaaa ttcctcggat ttgaacaaat ctttaaaaac
      961 gtcttgactg gacttcctat cggtggaggt aaaggtggat cagacttcga tcctaaaggt
     1021 aaaacagatg ctgaagtgat gcgcttctgc caaagcttca tgactgaatt gcaaaaacac
     1081 atcggaccat cacttgacgt acctgctggt gatatcggtg ttggtggacg tgaaattggt
     1141 tacctttacg gtcaatacaa acgtcttaac caatttgatg ctggtgtctt gactggtaaa
     1201 cctcttggat ttggtggtag cttgattcgt ccagaagcaa ctggttacgg tttggtttac
     1261 tatactgaag aaatgctcaa agctaacggt aacagctttg ctggtaagaa agtcgttatt
     1321 tcaggttctg gtaacgttgc tcaatatgct cttcaaaaag caactgaact cggtgcaact
     1381 gttatttctg tttctgactc aaatggttat gtcatcgatg aaaatggtat cgacttcgat
     1441 cttttggttg atgttaaaga aaaacgtcgt gctcgtttga ctgagtatgc agctgaaaaa
     1501 gcaactgcaa cctaccacga aggtactgta tggacttacg ctggaaacta tgacattgct
     1561 cttccatgtg ccactcaaaa cgaaatcaac ggtgaagcag ctaaacgttt ggttgctcaa
     1621 ggcgttatct gtgtatctga aggtgccaac atgccgagcg accttgatgc catcaaagtt
     1681 tacaaagaaa atggtatctt ctacggacct gcaaaagctg ccaacgctgg tggtgtagcc
     1741 gtttcagctc ttgaaatgag ccaaaacagt cttcgcctct catggactcg tgaagaagtt
     1801 gatggccatc tcaaagacat catgacaaac atcttcaaca cagctaaaac gacttcagaa
     1861 acatacggtc ttgataaaga ctaccttgca ggagctaaca ttgctgcctt tgaaaatgta
     1921 gcaaatgcca tgattgcaca aggtattgtt taagatttat ttactcaatc ctcaatcact
     1981 acgattgggg atttttagct tgaattaaaa aattggaaaa tctaattaaa taaaatgaaa
     2041 tgaaataaaa actgaacaaa ttgattgcgg aattcaaacc aatttctaac atacttctag
     2101 aaattaattt gacttttcta atcgatttgt tcatatctta tttcaattta ctatacttac
     2161 ttaacccttt ttatactcaa tgaaaatcaa agagcaaact aggaagcgag ccgcaggctg
     2221 tacttgagta cggcaaggca aagctgacgt ggtttgaaga gattttcaaa gagtattaaa
     2281 caaaaagaaa aaccgctact cctaagaata gcgatttaat catgttttta agctactact
     2341 gtagttgctc tattatttaa gtgttatgaa taacttcaat atctttaaag ctttttgtta
     2401 gatttataat ttcaactata gccatctcta ctccttagtt tacagcaaaa aattatgctt
     2461 aattcttatt gtttttgtaa acaatcagcg aacccaatac tattccattc aacaagccta
     2521 aagaaatacc atattcaact ggaaaatcta aaaaaattgc aaacactatt ccaatcatca
     2581 cccctagtga ggctgttgtt aaaattacat attcattttc tttcttcatt ttctttacac
     2641 ctcatttcct ttttgtatat aagctgtagt actctccacc aagctccatt aagtacttat
     2701 gatttcctga ctcaacaatc ttaccacctt tcattacaaa aataatatcc gcatccttaa
     2761 tcgttgacaa tctatgagct acaattattt gagtacagcc ctgacttttt atatactttg
     2821 ttattctttc ctcattaata gtgtctaaag cactagttgc ttcatctaaa attacaatac
     2881 taggattatt tattaatgca cgtgccagtg ctatccgttg tctttgacca cctgaaatat
     2941 ttgaacccat ctctgagatg atagtattaa atttcatcgg catagccatg atttcatcat
     3001 agatttgaac tgctttacaa acttcctcta tcttttgtga agtaacttcg ttctttaaag
     3061 ttatattatc aagaatactt cggttcaata aaaatgaatc ctgtggaact actcctaaat
     3121 tttgacttaa tattttttta tctatttgat taatatttat accatcaaat aaaacttttc
     3181 ctgtatcaat cttatataat cctgatggta tttttgataa tagacttcct gcaaaactag
     3241 aatcctagtt catgattgat aataccagca ctcaaattca ttcgt
//
LOCUS       DAVHKZ010000079         3083 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000079 DAVHKZ010000000
VERSION     DAVHKZ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3083
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.079"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     regulatory      complement(74..162)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(371..1000)
                     /locus_tag="VVO74_002180"
     CDS             complement(371..1000)
                     /locus_tag="VVO74_002180"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU5696117.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(1002..1784)
                     /gene="thiM"
                     /locus_tag="VVO74_002181"
     CDS             complement(1002..1784)
                     /gene="thiM"
                     /locus_tag="VVO74_002181"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU5696118.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(2027..2695)
                     /locus_tag="VVO74_002182"
     CDS             complement(2027..2695)
                     /locus_tag="VVO74_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU5696119.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVDKNREDLTELQQRWNQAVALELAFFDI
                     GYNV"
     regulatory      complement(2910..2998)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
BASE COUNT          958 a          663 c          437 g         1025 t
ORIGIN      
        1 aagaaaaaac tctaattaca gatacgaatt agagttcagc ttacaagatt agacagttct
       61 tttcgacata cgaaaaaaac atttcacatt tcccttcgcc agtcttaact gtatcaggtt
      121 caatgggtat catctcagcc taaagcaccc caaatgcctt tattatttaa ttatgtgatt
      181 attataacac acattttata ctagttcaag aaattgaact ggaaatacag ccttgcactc
      241 acaaagacag cagatctttc ttttgcaaaa aacaaatgac ctgtttgatg aattaaccat
      301 tcaagctgaa tctagacata gctttttaaa aaaggaaaat cctacttact tagaatccaa
      361 ggatagatat ctattgctca ctcatttccc gaacagtttt ttctatattt tttgcatacg
      421 atattgccga aatgattgaa acgccgtcaa cattggtctt tataatgtct ttaatatgtt
      481 tcgtctgtat cccaccaatt gcaactaaag gcatttgtgg caatagtttt ctcatcaatt
      541 caagaccttc ataacctata gcaccaccag catcatcctt tgactgggta tcaaatacag
      601 gaccaacacc aacataatct acatattcaa cttttgattg ttgaaattct tcctcgtttt
      661 ttatagaaag accaattatt ttatctggca tcaattttct aatttcatca acaccaatat
      721 catcttgacc tacatgtacg ccatcagcgt caatttccat tgccaaatcg atatcatcat
      781 taacgataaa cggcacattg tattttttac aaagttcttt aatttggata gctagctcaa
      841 gtttttctaa gccttctaaa gcaccctcac ctttttctcg aaattgaaat aaggttatac
      901 caccttttaa ggcttcctca acgactgtat atagattttt tccttggcaa gtagtcgttc
      961 cacaaataaa atatagtttt agtaattctt tatgaaacat cttacttcac tcttttgaat
     1021 tcctttacat cttcatctgt aatctcgtat aaggcattta taaattcaac tttaaatgtc
     1081 ccaggaagat gtccatttgg acgtttttct gccatttctc cagcgatatt gtaaaccaac
     1141 attgctgttt ctaatgattt caattcttga cctttttcta gtccgataaa gcttgctacc
     1201 actgccccta ataagcatcc tgtcccaatg actttcggca tcatagcact accattatga
     1261 atcgttacca cttctccatt aacagcaatg gcatccactt cacctgttac tactattgga
     1321 atattgaact tctcatttgc tgctagagca atttcgtcaa tattatctac gcccgcacta
     1381 tctactcctt tagatgccac atctattcct actaaagagg caatctcgcc agcatttcct
     1441 ctaatcgctg ctagtttata attgttgatt agatcatctg ctactttttt tctatattct
     1501 cctgctccac aggctacagg atctaaaact gctgggacat tatatttctc tgcaattttc
     1561 agagcagctt ggtataattt ccaattttca tctgtcaatg ttcctatgtt tattaataaa
     1621 ccaccagcat actttaacaa atcctctaaa tctgctggaa actcactcat ggctggtgag
     1681 gcgcccagtg ctactaatcc atttgctgtg aaatttttta ctacatcatt ggttatacaa
     1741 atgaccaatg gtgctttttc ttttaataat tttaaacttg tcatattgaa atccttcctt
     1801 ttcactttat acgatctact gatttcgatt tatttctatc tttcgttaag aatttttttc
     1861 atttacattg aatgatttat actcaatgaa aatcaaagag caaactagga ggctaaccgc
     1921 aggttgctca aaacactgtt ttgaggttgt ggatagaact gacgtggttt gaagagattt
     1981 tcgaagagtc ttacctcatc aaatttgtaa atatcatgag ccttctctag acattgtaac
     2041 caatatcaaa aaaagctaat tctaaagcga ctgcttgatt ccagcgttgc tgaagttctg
     2101 tcaaatcttc tcgattttta tcgacacgat tgagttcgtc aaccagaaat tgaacccact
     2161 ctgcaaagaa aggacctctg tggagattga tccattccga atgaatatag acttcaggta
     2221 aagccaaatc tttagaaccc cagtctaaat agagaccttc tgcaatgacc agcatgacca
     2281 aaagatgggc atagtctgat gaagccaccg ccgaatacat tagatcctga aaggcttttg
     2341 ttacagggtg caaagtcact tctagatagt cattctctgc tacttttaac tctttaaaag
     2401 ccttttggaa ataaccatct tcatctgctt caagaaagcc tagttgcttg gcaaaacgaa
     2461 gcttggattc aagtttatct gcgtgagcta cgcaggcacc cagcatggat aagaaggcat
     2521 caaagaagtg ataatcttga atcagatagt cctttaagac cttattctca attgtccccg
     2581 caaaaagttc cttaacaaaa cgatgattga ttgcagcctg ccaatccttc tgactgcttt
     2641 ttaataattc tccaacagtc aaacctggct gaaatgcata gtcttgtgtt tccatattta
     2701 cttctcctct ctttacttgt tagtaattaa taaaacacca agaaatatca agcaaaatcg
     2761 taattccact tgatcctttt aaagcacatc gagagcattt gcagagagct aactaaacaa
     2821 gcctatccag tttatataaa caaaaaactc caattacaat caagaattag agttgactta
     2881 caagattaga tcgttcattt cgccatacga aaaaacgttt cacatttccc ttcgccagtc
     2941 ttaactgtat caggttcaat gggtattatc tcagcctaaa gcaccccaaa tgtctctatt
     3001 atttaattac tgaaccagta tagcaaaaaa tgaaagccct agcaagatat ttgaccgaaa
     3061 aatatcttta tatataatat att
//
LOCUS       DAVHKZ010000080         3045 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000080 DAVHKZ010000000
VERSION     DAVHKZ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3045
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.080"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(8..250)
                     /locus_tag="VVO74_002183"
     CDS             complement(8..250)
                     /locus_tag="VVO74_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696120.1"
                     /translation="MKILNIKLANVEQTDSGFEHWVDVTYNVPILKNEYTVRLLLLFG
                     FEIEDPEVIEYLVNAWKYRELVLHSVRMYDMEREAS"
     gene            complement(482..1438)
                     /gene="lytA"
                     /locus_tag="VVO74_002184"
     CDS             complement(482..1438)
                     /gene="lytA"
                     /locus_tag="VVO74_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU5696121.1"
                     /translation="MDIDTSRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNTESYAAVELIESHSTKVEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLAD
                     RWKKYTDGNWYWFDNSGEMATGWKKIAEKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            complement(1444..1773)
                     /locus_tag="VVO74_002185"
     CDS             complement(1444..1773)
                     /locus_tag="VVO74_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEU5696122.1"
                     /translation="MQQITEIITNGAISILVILAGIAVKAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKG"
     gene            complement(1777..2076)
                     /locus_tag="VVO74_002186"
     CDS             complement(1777..2076)
                     /locus_tag="VVO74_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696123.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHTVGDIQKEMVRMNDRMEEIEKGE"
     gene            complement(2085..2435)
                     /locus_tag="VVO74_002187"
     CDS             complement(2085..2435)
                     /locus_tag="VVO74_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696124.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQFKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTVPTVEPKE"
     gene            complement(2438..2641)
                     /locus_tag="VVO74_002188"
     CDS             complement(2438..2641)
                     /locus_tag="VVO74_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696125.1"
                     /translation="MNTEQLNQALQMTIREMSTTSTDSMITSNILSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            complement(2622..2738)
                     /locus_tag="VVO74_002189"
     CDS             complement(2622..2738)
                     /locus_tag="VVO74_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
                     /protein_id="HEU5696126.1"
                     /translation="MNNNMLTNIALKAIQELALENRKRTHRLENLENEHRTA"
     gene            complement(2735..>3045)
                     /locus_tag="VVO74_002190"
     CDS             complement(2735..>3045)
                     /locus_tag="VVO74_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEU5696127.1"
                     /translation="KYWMEQKSDRRLKENITDTAVKALDKINRLRMVAFDFIENKKHE
                     EIGLIAQEAETIVPKIVSRDPENPDGYLHIDYTALVPYLIKAIQELNQKIEKMEKTIA
                     "
BASE COUNT          754 a          688 c          558 g         1045 t
ORIGIN      
        1 cagtatttta acttgcttct ctctccatat catacatcct cacagaatgt aagaccagct
       61 cacgatattt ccaagcgttg accaggtatt caatcacttc aggatcttca atttcaaaac
      121 caaagagcag caacaatcta accgtgtatt cgtttttcaa aattgggacg ttgtaagtca
      181 catccaccca atgctcaaag cctgaatctg tctgctctac atttgctagt ttaatattta
      241 aaatcttcat ttttattcct cctacttatc tattcgtaaa agaagataaa aagttatgaa
      301 aaaatcatta cttttttaat tcagacagta ctttcagagc aattttgtta atgtcaacaa
      361 aattggcaac caagcgattt aatactattt gttgacgcca acaagtcaat tttcagacaa
      421 acaaaaaaac cgcaagcctg agcctgcggt gaaagaacaa tttagaaagt ttcctttcta
      481 tttatttaac tgtaatcaag ccatctggct ctactgtgaa gtctggctta tctgccagtg
      541 ttccgtctgg tttgaggtag taccagcctg ttccgtctgc ggactggata aaggcatttg
      601 ataccatagc gccttcttta gcgtctaagt agtaccaagt gtccttgtac ttgacccagc
      661 ctgtcttcat ggcaccttct tcgttgaaat agtaccactt ctcagcaatt ttcttccagc
      721 ctgtagccat ttcgcctgag ttgtcaaacc agtaccagtt gccgtctgtg tacttcttcc
      781 agcggtctgc aagcatatag cctgagccat cgaaataata ccaggtaccg ttgattttct
      841 caaacttatc ttttggataa gagccgtctg aatgtacgta ccagtagcca gtgtcattct
      901 tctgccagcc tgtttcaatc gtcaagccgt tctcaatatc atgcttaaac tgctcacggc
      961 taatgcccca acttgcaaga tatggatatg gatccacatg gtctgagtgg ttgtttggtt
     1021 ggttattcgt gcaatactcg tgcgttttaa ttccagctaa actccctgta tcaagcgttt
     1081 tcggcaaacc tgcttcatct gctagattgc gtaagagttc gatataaagg cggtagtccg
     1141 tcatgaactc tactttagtt gaatggcttt caatcagttc aaccgctgcg taactctcag
     1201 tattccaacc gcccccaaca tcccaacttc cgttgttcac aggacctact tgcatgacac
     1261 ggccgtttcc gacaacatgt gaaaagaacc ctagttcagg gtcctttcta tagtggtaat
     1321 cagcctcatt ttgagctgtt gagttacggt tgcctgttga gtgggcgtgt acttgtcgat
     1381 aaggctgcac accgacctga ggcaagcctg tacgtagtct gcttgtatcg atatccatta
     1441 ctcttatcct ttccaagcgt cgttcatctg tttcactgcg gactctacga aggtgtctaa
     1501 gtctttgtca gtcatgctaa tattgtattt tgtaagctca gcacggactt tagcgcgagc
     1561 ctgtgccagt ttttcatctc ccttgtagcc agtttcagca gctacttgct caacggcatt
     1621 aactgcgttc ttagccaaga tttcaacaat cttgatagtc ttttctccac ctttttgaac
     1681 caggtagtcc ttgactgcct tgactgcgat accagccaaa ataacaagga tgctgattgc
     1741 tccattagta atgatttcag taatttgttg catttgttat tctccttttt cgatttcttc
     1801 catgcggtcg ttcatgcgaa ccatttcttt ttgaatgtct ccgaccgtgt gagtgattgt
     1861 ggttaattct gtagtggtct tttctaggtg agtcatcaaa cgctcttctc gtctattaga
     1921 gtcggccttt gattgctcgt gcaaatccat aatcttcttc tctcgcttgt ccgaagtctt
     1981 gataagatat cgaatgataa taaaaaaaag caagataaac aaaatcgccc aagctacctg
     2041 actttgagcg attttttcag cttcttcaat tggcatacaa cctcctattc tttaggttct
     2101 accgttggaa ccgtccagtc aggattgccc tctgcatcaa atttcatgat atagaattca
     2161 tgattcaaca gaacggctac gttgattgtt gcgattgtac caccccactg attgaacgcc
     2221 caaacggttt caacatcctt gaattggcga cggccattta caatcacagg acgtttttga
     2281 acgtcacgat acatatagaa gtcatcgctt acattcttgc aacgaatgaa ctctccattt
     2341 tctttcatgt agcgcaaagc gctcgcaaga tcaaatggtt ctgtgatttt tgtaaggtct
     2401 agtaagttat ctgtgttttg aattgtttct gccatgtcta ttctcctttg tctgctggtt
     2461 tagtttgttc atcaagcaga gcttccagct catccactcg tgcttgaagt ctttgattct
     2521 cttccctttg ctcattcaac tgaatactca agatattact tgtaatcatc gaatctgttg
     2581 aagttgttga catttcacga attgtcattt gtaaggcttg gttaagctgt tctgtgttca
     2641 ttttctaagt tctccaatct gtgtgttcgt tttctatttt caagagcaag ctcctgaatt
     2701 gctttaagtg cgatattggt caacatgttg ttattcatgc tattgttttc tccatttttt
     2761 ctattttttg atttaattct tgaatagcct tgattaagta aggaactaaa gcggtatagt
     2821 cgatatgcag atagccatct ggattctcag gatctcgtga gacaattttt ggaacgatgg
     2881 tttcagcctc ttgagctatt agaccaatct cctcatgttt cttattttcg atgaaatcaa
     2941 atgcaaccat tcttaatctg ttgattttgt ccaaggcttt cacagctgta tctgtgatgt
     3001 tctcttttaa gcgtctgtct gatttttgtt ccatccaata cttca
//
LOCUS       DAVHKZ010000081         2994 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000081 DAVHKZ010000000
VERSION     DAVHKZ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.081"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            61..777
                     /locus_tag="VVO74_002191"
     CDS             61..777
                     /locus_tag="VVO74_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEU5696128.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGAAKTEQTAKADGTVG
                     SKAQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELLKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(817..954)
                     /locus_tag="VVO74_002192"
     CDS             complement(817..954)
                     /locus_tag="VVO74_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696129.1"
                     /translation="MKIKEQTRKLAAGCSKYSFEIADKTDEVSSKHCFEVVNRTDAVS
                     R"
     gene            1086..1511
                     /gene="rplK"
                     /locus_tag="VVO74_002193"
     CDS             1086..1511
                     /gene="rplK"
                     /locus_tag="VVO74_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU5696130.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            1719..2408
                     /gene="rplA"
                     /locus_tag="VVO74_002194"
     CDS             1719..2408
                     /gene="rplA"
                     /locus_tag="VVO74_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU5696131.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
BASE COUNT          999 a          561 c          677 g          757 t
ORIGIN      
        1 aagattagtc aaacgtttat cgttagaagt agataaacta ttagaaataa aggagtagaa
       61 atgaaaaaaa gatacctagt cttgacagct ttgctagcct tgagtctagc agcttgttca
      121 caagaaaaag caaaaaatga agatggagca gctaaaacag aacaaacagc taaagctgat
      181 ggaacagtag gaagtaaggc tcaaggagct gcccagaaaa aagcagaagt ggttaacaaa
      241 ggagactact acagcatcca agggaaatac gatgaaatca tcgtagccaa taaacactat
      301 ccattgtcta aagactacaa tccaggtgaa aatccgacag ccaaggcaga attgctcaaa
      361 ctcatcaaag caatgcaaga ggcaggtttc ccgattagcg atcattacag tggttttaga
      421 agttatgaaa ctcagaccaa gctctatcaa gattatgtta accaagatgg gaaggcagca
      481 gctgaccgtt actctgcccg acctggctat agtgagcacc agacaggctt ggcctttgat
      541 gtgattggga ctgatggtga tttggtgaca gaagaaaaag cagcccaatg gctcttggat
      601 catgcagctg attatggctt tgttgtccgt tatctcaaag gcaaggaaaa ggaaacaggc
      661 tatatggctg aggaatggca cctgcgttat gtaggaaaag aagctaaaga aattgctgca
      721 agtggtctca gtttggaaga atactatggc tttgaaggcg gagactacgt cgattaatac
      781 tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac ctactgactg cgtcggttct
      841 attcacaacc tcaaaacagt gttttgagct gacttcgtca gttttatctg caatctcaaa
      901 gctgtacttt gagcagcctg cggctagctt cctagtttgc tctttgattt tcattgagta
      961 taaaaaataa acttttctct tgcaattcca gataaatagt gtataatgga tgggtatgtg
     1021 aaaaacatac ttgtgggagg taaaaatctc taattaccgc caaaaccaca aaggaggatt
     1081 taaaaatggc taaaaaagtc gaaaaacttg taaaattgca aatccctgct ggtaaagcta
     1141 caccagctcc accggttgga cctgctcttg gtcaagctgg tatcaacatc atgggattca
     1201 caaaagagtt caacgctcgt acagctgacc aagctggtat gatcattcca gttgttatct
     1261 cagtttacga agacaaatca tttactttcg ttacaaaaac accaccagct gctgttcttt
     1321 tgaaaaaagc tgcaggtgtt gaaaaaggat caggtacacc taataaaact aaagttgcta
     1381 cagttactcg tgcacaagta caagaaattg cagaaactaa gatgccagat ttgaacgcag
     1441 caaacgtaga gtctgcaatg cgtatgatcg aaggtactgc tcgttctatg ggattcactg
     1501 ttgttgacta atcaataaca cagtagaaaa tctcacagca gtctattagt tgcttttcat
     1561 actaggcaag tgactgagcc ttgtacttgg gtacagcaag ggagcttaag gccgtaggaa
     1621 gagaaaaata gtagactgaa aacccgcaag acttcatcat ttcgagaagt gacgtgggag
     1681 atgaaaatcg attgaaccac ttacaaggag aatagaaaat ggctaaaaaa agcaaacaac
     1741 ttcgtgctgc tcttgagaaa atcgacagca caaaagcata cagtgtagaa gaagctgtag
     1801 cacttgcaaa agaaactaac tttgcaaaat ttgacgcaac tgtagaagtt gcttacaact
     1861 tgaacatcga cgttaaaaaa gctgaccaac aaatccgtgg agcaatggta ttgccaaacg
     1921 gtactggtaa aacttcacgt gttcttgttt tcgcacgtgg tgcaaaagct gaagaagcaa
     1981 aagctgctgg tgcagacttt gttggtgaag atgaccttgt tgctaaaatc aacgacggtt
     2041 ggttggactt cgacgtagtt atcgctacac ctgatatgat ggctcttgtt ggacgtcttg
     2101 gacgtgtcct tggaccacgt aacttgatgc caaaccctaa aactggtact gtaacaatgg
     2161 atgttgctaa agcagttgaa gagtctaaag gtggtaaaat cacttaccgt gctgaccgtg
     2221 caggtaacgt tcaagcaatc atcggtaaag tatcatttga agctgaaaaa ttggttgaaa
     2281 actttaaagc tttcaacgaa acaatccaaa aagcaaaacc agctacagct aaaggaactt
     2341 acgtaacaaa cttgactatc acaactactc aaggtgttgg tatcaaagtt gacgtaaact
     2401 cactttaatc agtagttaaa gtaatgtaaa aaagttgaag acactatgtc tcaacttttt
     2461 ttgatgtacg acgggcatgt cgtatatctg aggtgtaagt cctcggtggg cacctactac
     2521 cggtgaaccc aatagcgatt cccaagtctg actatcgtga ggtagcggat taaaacggtc
     2581 tggggataga ccgttttaag tctgacgctg gaaataagaa tcgtcagagg aagggatagc
     2641 gaaatcgtgg ctctacgaac aggaacgtga taataaggcg tatatagcgg ataaggtatc
     2701 tggctggggc gaccactatc aattataata aaatgaaata agaataggac gaatcgttca
     2761 ggacagtcaa atcgatttct aacaatgttt tagaagtaga ggtgtactat tctagtttca
     2821 atctactata gtagctcaga agtcggtact taaacgtgct atatcaaaac cagtccttga
     2881 aaaacgtgga ctggtttcgt gtttggatta ttaccttgaa cgacatgcgt taaaagttag
     2941 ttgaaccgcc gtatgccgaa cggcacgtac ggtggtgtga gaggggctag agat
//
LOCUS       DAVHKZ010000082         2952 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000082 DAVHKZ010000000
VERSION     DAVHKZ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2952
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.082"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(85..1026)
                     /locus_tag="VVO74_002195"
     CDS             complement(85..1026)
                     /locus_tag="VVO74_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU5696132.1"
                     /translation="MKQAKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="VVO74_002196"
     CDS             complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="VVO74_002196"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU5696133.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETSKTN"
BASE COUNT          859 a          697 c          591 g          805 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacataca tacggtaagg cgacgctgac gtggtttgaa
       61 gagattttcg aagagtatta atcactaatt atctatctca acaaatcttc ctagaatatg
      121 aacattttcc gagacagaga caaaggagct tggatccact tgtgtcataa tctgtttaaa
      181 ttcattaaac tctgcacgtg taatgacagt gattaaaact gcctttctct cgtgattata
      241 ggttccttct gcatcatgga tcatggttgc tccgcggtgc aattttttat ggattttttc
      301 aattaccttc tctggatgat ttgtcacaat catggcctgc atacgctttt gcttagtaaa
      361 gactgcgtct gtcacacggc tagagacaaa gatggtaatc atagaataaa gagcgtattt
      421 ccaaccaaag gtcaaacctg ctatcagcat gatagttcca tttaccaaga aagaaatact
      481 accaacattc ttacccgttt tcttgcgaat agtcaggctg acgatatccg tcccaccact
      541 ggagatattg tttcgaagag caaaaccaat ccccaaaccc ataacaacac ccccaaaaag
      601 ggcattgata atgggatcct ccgtcaaggt tgccacaggg acaaactgga taaagaagga
      661 actcatagat accgtgataa aggtaaagac ggtgaactta tggccaatct gataccaagc
      721 taagaccatc aaagggaagt taatggcgta gaagcttagc gaaatcggaa tatgaaaacc
      781 aaaccagtga ttactcaagg cagagataat ctgtgccaga cctgttgcac cactcgaata
      841 cacatgccct ggttggaaaa agaaattaac tgctactgct gataaaaaac catagaccag
      901 agaggccgaa atcttctcat catacttttc tcgagagata ctttgtaaga cacgtaaaat
      961 ttttatctga taagcaaagc ggcgcagata atagcgccac cgcttaattc gttttgcttg
     1021 tttcatcttc ttctacttgt aagctgagtt cctctagttg tttgagagcg actgttgatg
     1081 gagcttgtgt cattgggtca gttgccttgt tgttcttagg aaaggcaatg acttcacgga
     1141 tattttcttc tccagcaagc aacatgacaa aacggtcaag cccgatagcc aaaccaccgt
     1201 gtggtgggaa accatagtcc atggcttcaa gaaggaaacc aaactggtca ttggcttctt
     1261 cagctgagaa accaagagcc ttgaacatgc gttcttgaag gtctttttgg ttgatacgaa
     1321 ggctaccacc accaagctca taaccgttca agacgatatc gtaagcaatg gcacgaacct
     1381 tagccaaatc accttctaat tcgtgagcag tctcttcctg tggaagtgtg aatggatggt
     1441 gggcgctcat gtagcggcct tcttcttcag accattcaaa catcggccag tcaaccaccc
     1501 aaaggaagtt gaacttatca ttatcaatca agccaagctc tttagcaata cgtccacgaa
     1561 gggcacccag tgttgcatta gccacttcaa gcgtatccgc cacaaagaga accaagtcct
     1621 tatcttcaag agcaagcgct gttgtcaatt cttcttggat accagtcaag aacttggcaa
     1681 ctggtccgtt taattctcca tcaaccacct tgacccaagc aagacctttg gcaccatact
     1741 gtttggctac ttccgtcatc ttgtcgatgt ctttacgtga atagttgtcc gcagctcctt
     1801 tgaccacaat cgcttttaca gcaggtgctt ctgaaaagac tttaaagtct acacctttga
     1861 ccacttctgt caagtcctga agcaacatgt caaaacgagt atctggcttg tcagaaccgt
     1921 aaagagccat agcatcatcg tatttcatac gagggaacgg tagcgttact tcgatgcctt
     1981 ttgtttcctt catcacgcgc gcgatcaagc cttctgtaat atcttggatt tctttctcag
     2041 taaggaagga cgtttccaag tcgacctgag taaattcagg ctggcggtct ccacgcaagt
     2101 cctcgtcacg gaaacattta acgatttggt agtaacggtc aaaaccagca ttcatcaaga
     2161 gctgtttcgt gatttgtgga ctttgaggaa gagcgtaaaa atgcccctta ttaacacgag
     2221 acggcactaa ataatcacgc gccccttcag gcgttgactt agaaaggaat ggtgtctcca
     2281 cgtcgataaa ctccaactca tccaaatagt tgcggataga gtgggtcacc ttggcacgaa
     2341 gtttaagatt ttccaacatt tctggacgac gaaggtcaag gtaacggtaa cgcaaacgtg
     2401 tatcgtcatt tgcctcaatg ccatccttaa tctcaaatgg tgttgtctta gctgtgttaa
     2461 gcacaataag agctgtcacg tttaactcaa ccgcaccagt tggcaactta tcattggctt
     2521 gctcacgcgc agcgacctga ccagtcacct caataacaaa ttcgctacga aggctttcag
     2581 ctgttgccat aacctctgca gatacttttt cagggttgat aaccaactgc atgattcctt
     2641 cacggtcacg aagatcgata aagatcaaac caccaaggtc acgacgacgg ccaacccatc
     2701 ctttcaaggt tatttcttgt ccgatgtgtt cctcacgaac acgaccagca tacatactac
     2761 gtttcattat ttctctcctc ttttattctg ttactatttt accataaaag cgcaggctct
     2821 tcatgaaaat catcagaaaa gtttgccagt ctttaaaagt caggtgaaag ccctaaaaat
     2881 tagcgctaat actcttcgaa aatctcttca aaccacgtca gcgtcgcctt accgtaggta
     2941 tggttactga ct
//
LOCUS       DAVHKZ010000083         2596 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000083 DAVHKZ010000000
VERSION     DAVHKZ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2596
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.083"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..375
                     /locus_tag="VVO74_002197"
     CDS             <1..375
                     /locus_tag="VVO74_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU5696134.1"
                     /translation="IGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGEREADFVNM
                     VLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLLESRAQRA
                     MRENNAGQDLADLVLEEEELPF"
     gene            645..929
                     /gene="groES"
                     /locus_tag="VVO74_002198"
     CDS             645..929
                     /gene="groES"
                     /locus_tag="VVO74_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU5696135.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            945..2567
                     /gene="groL"
                     /locus_tag="VVO74_002199"
     CDS             945..2567
                     /gene="groL"
                     /locus_tag="VVO74_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU5696136.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
BASE COUNT          798 a          511 c          612 g          675 t
ORIGIN      
        1 attgggcgtt taacgtctac accagaattg cacaaaacca acaatgacaa gtcggtagcg
       61 cgagcaacta tcgctgtcaa ccgtcgttac aaagaccaaa acggtgaacg tgaagctgat
      121 tttgtcaata tggtcctatg gggcaggcta gcagaaactt tggcaagcta cgcaaccaaa
      181 ggtagtctca tttccgttga tggagaattg cgtacccgtc gctttgagaa aaatggtcag
      241 atgaactatg taaccgaagt ccttgtgaca ggattccaac tcttagaaag tcgtgctcaa
      301 cgtgccatgc gtgaaaataa tgcaggccaa gatttggcag atttggtctt ggaagaggaa
      361 gaattgccat tttaatactc ttcgaaaatc tcttcaaacc acgttagctt tatccacaac
      421 atcaaagcaa tgctttgagc agcctgcggc tagcttccta gtttgctctt tgattttcat
      481 tgagtataaa cattaaaaag tctgagttgg tctcaggctt tttatcttga gaaagtcaga
      541 cttttttctt gactatttct gaccaagtga tacaatagaa ttatgaatta gcactcaagt
      601 tcaaagagtg ctaataatat ctatctcatt atggaggaaa tcagatgttg aaaccattag
      661 gggaccgtgt ggtcttaaaa atagaagaaa aagaacaaac cgttgggggc tttgtccttg
      721 caggctcagc ccaagaaaaa accaaaacag ctcaagttgt ggctactgga caaggtgttc
      781 gtaccttgaa cggtgacttg gttgctccaa gtgttaaaac tggagatcgt gtcttagttg
      841 aagcccacgc aggtcttgat gtcaaagatg gcgatgaaaa gtacatcatc gtaggcgaag
      901 ctaacatctt ggcaatcatt gaggaataga aggagaaagt aagtatgtca aaagaaatta
      961 aattttcatc agatgcccgt tcagccatgg ttcgtggtgt cgatatcctt gcagacactg
     1021 ttaaagtaac cttgggacca aaaggtcgca atgtcgttct tgaaaagtca ttcggttcac
     1081 ccttgattac caatgacggt gtgaccattg ccaaagaaat cgaattggaa gaccattttg
     1141 aaaatatggg tgctaagtta gtatcagaag tagcttctaa aaccaatgat atcgcaggtg
     1201 acggaactac gactgcaaca gtcttgaccc aagctatcgt ccgtgaagga atcaaaaacg
     1261 tcacagcagg tgcaaatcca atcggtattc gtcgtgggat tgaaacagca gttgccgcag
     1321 cagttgaagc tttgaaaaac aacgccatcc ctgttgccaa taaagaagct atcgctcaag
     1381 ttgcagccgt atcttctcgt tctgaaaaag ttggtgagta catctctgaa gcaatggaaa
     1441 aagttggcaa agacggtgtc atcaccatcg aagagtcacg tggtatggaa acagagcttg
     1501 aagtcgtaga aggaatgcag tttgaccgtg gttacctttc acagtacatg gtgacagata
     1561 gcgaaaaaat ggtggctgac cttgaaaatc cgtacatttt gattacagac aagaaaattt
     1621 ccaatatcca agaaatcttg ccacttttgg aaagcattct ccaaagcaat cgtccactct
     1681 tgattattgc ggatgatgtg gatggcgagg ctcttccaac tcttgttttg aacaagattc
     1741 gtggaacctt caacgtagta gcagtcaagg cacctggttt tggtgaccgt cgcaaagcta
     1801 tgcttgaaga tatcgccatc ttaacaggcg gaacagttat cacagaagac cttggtcttg
     1861 agttgaaaga tgcgacaatt gaagctcttg gtcaagcagc gagagtgacc gtggacaaag
     1921 atagcacggt tattgtagaa ggtgcaggaa atcctgaagc gatttctcac cgtgttgcgg
     1981 ttatcaagtc tcaaatcgaa actacaactt ctgaatttga ccgtgaaaaa ttgcaagaac
     2041 gcttggccaa attgtcaggt ggtgtagcgg ttattaaggt cggagccgca actgaaactg
     2101 agttgaaaga aatgaaactc cgcattgaag atgccctcaa cgctactcgt gcagctgttg
     2161 aagaaggtat tgttgcaggt ggtggaacag ctcttgccaa tgtgattcca gctgttgcta
     2221 ccttggaatt gacaggagat gaagcaacag gacgtaatat tgttctccgt gctttggaag
     2281 aacctgttcg tcaaattgct cacaatgcag gatttgaagg atctatcgtt atcgatcgtt
     2341 tgaaaaatgc tgagcttggt ataggattca acgcagcaac tggcgagtgg gttaacatga
     2401 ttgatcaagg tatcattgat ccagttaaag tgagtcgttc agccctacaa aatgcagcat
     2461 ctgtagccag cttgattttg acaacagaag cagtcgtagc caataaacca gaaccagtag
     2521 ccccagctcc agcaatggat ccaagcatga tgggcgggat gatgtaagct ttctatagaa
     2581 aacaacttat aaaaaa
//
LOCUS       DAVHKZ010000084         2532 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000084 DAVHKZ010000000
VERSION     DAVHKZ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2532
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.084"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..559
                     /locus_tag="VVO74_002200"
     CDS             <1..559
                     /locus_tag="VVO74_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU5696137.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="VVO74_002201"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="VVO74_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEU5696138.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1424..2026
                     /locus_tag="VVO74_002202"
     CDS             1424..2026
                     /locus_tag="VVO74_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU5696139.1"
                     /translation="MVKLTTCYFCDYGSYYGNIPMNWVVIKIKDIFSINTGLSYKKGD
                     LSINKGVRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIG
                     KFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQAL
                     YNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQLWK"
     gene            complement(1974..>2532)
                     /locus_tag="VVO74_002203"
     CDS             complement(1974..>2532)
                     /locus_tag="VVO74_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU5696140.1"
                     /translation="NKDETTSYPIYEIPKAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIISKVDLLFQKVSQLFE"
BASE COUNT          864 a          364 c          438 g          866 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggagtgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagagat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgg
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcgggag ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg ccgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttaga
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtgattatg gctcttatta tgggaatata cctatgaatt gggttgttat
     1501 aaaaataaaa gatatttttt caataaatac aggtctttct tacaagaagg gcgatttaag
     1561 cattaataaa ggtgttagaa ttatacgtgg tggtaatatt aagcctttag aattttctct
     1621 gttggataat gattactaca ttgacacaca attcatctcc tctgagcaag tttatttaaa
     1681 acataatcag ctaataacac ctgtatcaac ctctttagaa catattggaa agtttgcaag
     1741 aatcgataaa gactatgatg gtgttgtggc tggtggattt attttccaat taacaccatt
     1801 cgaaagttca gagattattt caaaatttct attatttaac ttgtcctctc cgttatttta
     1861 taaacaattg aaagcaataa ctaaactatc aggtcaagct ttatataata ttcctaaaac
     1921 tacactaagc gagctattaa ttccgttagc tccttttgag gaacaggaac ttattactca
     1981 aaaagttgag aaactttttg aaaaagtaaa tcaactttgg aaatgattct tttcatctct
     2041 tcatgattag aaatagggat taataattcg gagatactgg tactatttaa tgttttccct
     2101 ttgatagcat cttttgaatc acctaaagta gagataagtg gcaaaaatat cattaagtaa
     2161 tctctgataa tattttcttt attagcatag gggaatatcg atataatggc ttcattatga
     2221 gtggcaggaa tatccaatat ggcaactttt ccaatagata atttaaaact cattaataaa
     2281 gttcctttag gtgaaatgtc tattttcttt gattttaatg ctaatttaga aatagattct
     2341 ctcgtattag ttacataacc agatataggc atatctgata tagataccca gggtatttca
     2401 gttccccaaa aagtagcttc actgcgtgga ggagtttttc ctattctgaa gttaactagg
     2461 ctagcaaatt taatatatct ccatgctttt gggatttcat atataggata agaggttgtt
     2521 tcgtctttgt tc
//
LOCUS       DAVHKZ010000085         2223 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000085 DAVHKZ010000000
VERSION     DAVHKZ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2223
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.085"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(1..364)
                     /locus_tag="VVO74_002204"
                     /pseudo
     CDS             complement(1..364)
                     /locus_tag="VVO74_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            837..>2223
                     /gene="pcpA"
                     /locus_tag="VVO74_002205"
     CDS             837..>2223
                     /gene="pcpA"
                     /locus_tag="VVO74_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEU5696141.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGV"
BASE COUNT          789 a          328 c          363 g          743 t
ORIGIN      
        1 tcctcagaac tgagaggagt tcttgaaacc gtaaaaccac tttgaacaag agttacttca
       61 acccattggc tccgacggat aaagttgctt tcgtgaatac caaaatcagc cgcaatttct
      121 tcataagttc gatattctcg cactattgaa gagtgggcat aagaaggtct tctaggctta
      181 atttaggttt tcgtccacct tttgcgtgtt taagttgata agctgttttt aatacagcta
      241 acatctcttc aaaagtcgtg cgttgaacac caacaagacg cttaaatcgt gcatcggtta
      301 gttgtttact tgcttcataa ttttgtttcg cagggagtct attgactctt tggtaggtgt
      361 caatgttttt ttcatctatc ccgagaatta ttttcccgcc atttgtattt gcaaatgctg
      421 agtaggtttc ccagaaagac tctggaagat tgtttttagc ttttttgtat tctaaatcaa
      481 ccccttcaaa ttttaagtcc atatttttcc tttacatctg ttttttgtgg ttctggtatt
      541 tgttcaagtt gagtgataat atagcgaatt gaatttcgag agtttttact cagttaattt
      601 cttttttaac ccactttaat ttctttttta acacgggtta aaaaagaaat taaagtgggt
      661 taattttcct tgacttaaaa tttaaaaatg atatactgtg tttatggaga gatgacaatt
      721 tataaaatgt actactctat tctactagat aatgattgaa taaaactttt tataacaacg
      781 gctagcaaag ttataatttt atatctatta gaaaataaat atgtaaggaa atttaaatga
      841 aaaaaactac aatattatca ttaactacag ctgcggttat tttagcagca tatgtcccta
      901 atgaaccaat cctagcagat actcctagtt cggaagtaat caaagagact aaagttggaa
      961 gtattattca acaaaataat atcaaatata aggttctaac tgtagaaggt aacataggaa
     1021 ctgttcaagt gggtaatgga gttactcctg tagagtttga agctggtcaa gatggaaaac
     1081 cattcacgat tcctacaaaa atcacagtag gtgataaagt atttaccgtt actgaagtag
     1141 ctagtcaagc ttttagttat tatccagatg aaacaggtag aattgtctac tatcctagct
     1201 ctattactat cccatcaagc ataaaaaaaa tacaaaaaaa aggcttccat ggaagtaaag
     1261 ctaaaactat tatttttgac aaaggcagtc agctggagaa aattgaagat agagcttttg
     1321 atttttctga attagaagag attgaattgc ctgcatctct agaatatatt ggaacaagtg
     1381 cattttcttt tagtcaaaaa ttgaaaaagc taaccttttc ctcaagttca aaattagaat
     1441 taatatcaca tgaggctttt gctaatttat caaatttaga gaaactaaca ttaccaaaat
     1501 cggttaaaac attaggaagt aatctattta gactcactac tagcttaaaa catgttgatg
     1561 ttgaagaagg aaatgaatcg tttgcctcag ttgatggtgt tttgttttca aaagataaaa
     1621 ctcaattaat ttattatcca agtcaaaaaa atgacgaaag ttataaaacg cctaaggaga
     1681 caaaagaact tgcatcatat tcgtttaata aaaattctta cttgaaaaaa ctcgaattga
     1741 atgaaggttt agaaaaaatc ggtacttttg catttgcgga tgcgattaaa cttgaagaaa
     1801 ttagcttacc aaatagttta gaaactattg aacgtttagc cttttacggt aatttagaat
     1861 taaaagaact tatattacca gataatgtta aaaattttgg taaacacgtt atgaacggtt
     1921 taccaaaatt aaaaagttta acaattggta ataatatcaa ctcattgccg tccttcttcc
     1981 taagtggcgt cttagattca ttaaaggaaa ttcatattaa gaataaaagt acagagtttt
     2041 ctgtgaaaaa agatacattt gcaattcctg aaactgttaa gttctatgta acatcagaac
     2101 atataaaaga tgttcttaaa tcaaatttat ctactagtaa tgatatcatt gttgaaaaag
     2161 tagataatat aaaacaagaa actgatgtag ctaaacctaa aaagaattct aatcagggag
     2221 tag
//
LOCUS       DAVHKZ010000086         1818 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000086 DAVHKZ010000000
VERSION     DAVHKZ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1818
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.086"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..>1818
                     /locus_tag="VVO74_002206"
     CDS             <1..>1818
                     /locus_tag="VVO74_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696142.1"
                     /translation="WSPAPEDADGLITEAKATFERTAQGLRTDLSAIQEYVNKDGQRQ
                     EALQRYTREESTRQATAVRELVNRDFVGKVTYQEDVKGINQRIEAVKTSANKDIASQI
                     ASYRQSVDGKFTDISSQITTYKQDVGGQISGLSNRLTSSEQGTTTQISNLSNRINSNK
                     QGTDNQISNLKTQVATNKDNAERQMGRISDQVSANKANADSQFANVTNQLVRKVETTD
                     FQRVKETSKLYERILGNTENGIADKVARMALTNQLFQVEVGKYSVSGPNLIKNSDFKN
                     ATNEWGSTQNLGRLVKHSFYHNGQKDLMRLSNATKNENFLYSHRFNLERNTDYVLNFR
                     GFNNSALASYDVYILGRRAGESDGFTIVKKVVSSKKLSTSRCEDVSVTFNSGEMDNAY
                     IRFDNNGSSSGTADLYITEVDLYKGYKPRTWQPHPEDAVADANKKLEATQTKMTQLAG
                     SWVVENINSAGDIISGINLGANGHNRLVGKLTHITGETLIDRAVIKSAMVDKLKTANF
                     EAGSVTTTILEAEAVTAEKLKVDDALIRKLTAKDAFIDRLTSKRIFSTKVESVISSST
                     FLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAG"
BASE COUNT          586 a          341 c          422 g          469 t
ORIGIN      
        1 tggagccctg cgcctgagga cgctgatggt ctcatcactg aggctaaggc tacctttgag
       61 cggacagctc agggcttgcg aaccgactta tcagctattc aggaatatgt aaataaagac
      121 ggtcagcgac aggaagccct acagcgctat actcgtgagg agagcacgag acaagcgaca
      181 gcagtccgtg agctggtcaa tcgtgatttc gttggtaagg ttacttatca agaagatgtt
      241 aagggtatca atcagaggat tgaagctgtt aaaactagtg cgaataaaga catcgctagt
      301 caaatcgcta gctatcgtca atctgtagat ggtaagttca cggatatttc aagtcagata
      361 actacttata agcaagatgt gggcggtcaa atcagtggcc tttcaaatag acttacaagc
      421 agtgaacaag gaaccactac tcagatttca aatctttcaa atcggataaa cagtaacaaa
      481 caaggcacag ataatcagat ttcaaattta aagactcagg tcgctacaaa caaggataat
      541 gctgaacgac aaatgggtag aatatctgat caggtttctg caaacaaagc gaatgctgat
      601 agtcaatttg cgaatgtgac caatcaacta gtgcgaaaag tagagactac tgacttccag
      661 cgtgttaagg aaaccagtaa actttacgag cggattttgg gcaatactga aaatggaatt
      721 gcggataagg ttgctcgcat ggctctgacc aatcaactat ttcaggttga ggttgggaaa
      781 tatagtgtaa gcggccctaa cctcattaag aatagtgatt ttaaaaatgc tacgaatgaa
      841 tggggctcaa ctcaaaattt aggaagattg gttaagcata gcttttatca caacgggcag
      901 aaagacctta tgcgtttaag taatgcaact aaaaacgaaa actttttgta tagtcaccgt
      961 tttaatcttg aacgaaatac tgactatgta ctgaatttta gaggatttaa caacagtgct
     1021 ctagcaagct atgatgttta tattttggga cgaagagcag gcgagagcga tggattcaca
     1081 atcgttaaga aagttgttag cagcaagaaa ctatctacct ctagatgcga agatgtctca
     1141 gtaactttta attccggaga aatggataat gcttacattc gttttgataa caatggctca
     1201 tcatcaggaa cagctgattt gtatattaca gaagttgact tgtacaaagg ttataaacct
     1261 agaacatggc aaccacatcc agaagatgca gtcgcagatg cgaataagaa gcttgaagca
     1321 acgcaaacaa aaatgactca actagctggc tcatgggtag ttgaaaacat caactcggct
     1381 ggagatatca tctctggaat caatcttggc gccaatggac ataaccgctt agttgggaaa
     1441 ttgacccaca tcactggaga gaccctgatt gacagagcag tcatcaagtc tgccatggtt
     1501 gataagctca aaacggccaa ttttgaagct ggttcggtca cgactacgat attagaagct
     1561 gaagcggtaa ctgctgagaa gttgaaagtt gacgatgcgc ttattagaaa attaactgca
     1621 aaagatgctt ttattgaccg actgacatct aaacgtatct tctctactaa ggttgagtcc
     1681 gtcatttcta gctcaacctt cctagaagcc tatcaaggcc gaattggtgg attcacactt
     1741 ggtcaatttg accagggtgg cggtcgctgg atttcaggtg tcaatcagtt ctctgttggt
     1801 atggggaatg gtgccggg
//
LOCUS       DAVHKZ010000087         1733 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000087 DAVHKZ010000000
VERSION     DAVHKZ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1733
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.087"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            77..484
                     /locus_tag="VVO74_002207"
     CDS             77..484
                     /locus_tag="VVO74_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU5696143.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQTDEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKIG"
     gene            649..948
                     /locus_tag="VVO74_002208"
     CDS             649..948
                     /locus_tag="VVO74_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU5696144.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1209..1532
                     /gene="tnpB"
                     /locus_tag="VVO74_002209"
     CDS             1209..1532
                     /gene="tnpB"
                     /locus_tag="VVO74_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU5696145.1"
                     /translation="MIIQLSDLGQVHLVCSKIDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPQI"
BASE COUNT          577 a          335 c          309 g          512 t
ORIGIN      
        1 taataacgat actagataat gaggaaaatg caatggcaaa cccaactctc ggagaaaaaa
       61 agcgaataca gactatattg ctcgctatgg cgtatatgca gttatcccta atcctgaaca
      121 aaaacaaatt gttcttgttc aagaaccaaa tggtgcttgg ttcctaccat gtggagaaat
      181 tgaagcaggt gaaaatcatc aggaagccct aaagcgtgag ttgattgaag agcttggttt
      241 cacagcagaa attggtacct attacggaca aactgacgaa tatttctatt ctcgtcatcg
      301 tgatacctac tactacaatc ctgcctacct ctatgaagca acttctttca aagaagtaca
      361 aaagccacta gaaaacttta atcatattgc ctggttccct attgacgagg ctatccaaaa
      421 ccttaaacgt ggtagccata aatgggccat tgaatcttgg aaaaaacagc ataagattgg
      481 ctaatactct tcgaaaataa aattcaaacc acgtcagcgt cgccttaccg tactcaagta
      541 tagcctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa atcaagcgac
      601 tttattcaaa aagtgctata atagaattag aaaatcggag gaaatattat gaagcttatc
      661 aatacgacaa actcacactc gcaacttgta aaaagtcaac tagaaagtac cgatgcaacc
      721 cttgttgagg tttattctgc agggaataca gatgttattt ttacccaagc tccgcttcac
      781 tatgaaatcc tcatctcaaa caaacaccgt gctattcgtg agcctgaaat cgaaaccatt
      841 caagaatttt tcttgaaacg taaaattgat aaggcctctg ttgatgaagc caatatcaag
      901 acactctact cagagaaatt aattggaatt tcaatcccaa tcaagtaaga aaattgagta
      961 aaaactcgat ttgagagaaa gtccaataag tctttccata acaaaacgca tagtaacaag
     1021 agtttctaca cccactatta tacgttttta tcattttgaa atctgctgct aatcaatgaa
     1081 gaagcaaaga tcaaactaag cagctagtta caagttacgt aagcgcgtca taacaaggta
     1141 tctatcctaa ttccccaact tccagtatac tagataaaaa ataattatcg gaggaaaggt
     1201 attgtactat gataattcaa ctaagtgatt taggtcaagt tcaccttgtt tgtagcaaga
     1261 tagatatgag gcagggaata gactcattag cctatgtagt taaaacccac tttgaattgg
     1321 atcctttctc cggtcaagtc tttctctttt gtggtggacg taaagaccgc tttaaagccc
     1381 tttactggga tggtcaagga ttttggctac tatataaacg ctttgagaac ggcagactga
     1441 cttggcccag tacagaaaag gatgtcaaag ctctcacacc tgaacaagta gactggctta
     1501 tgaagggctt ttctatcact ccccaaatat agtggattta aactagaata gtacacctct
     1561 gcttctaaaa cattgttaga aatcgatttg actgtcctga tcgatttgtc ctgttcttgt
     1621 ttcattttac tatagaacga tttgaaggcg tttataatat ttagctgtac gagagtcttt
     1681 aaaagtgttt tgatggtttg gatttcttct ttagttgatt tcatatcact att
//
LOCUS       DAVHKZ010000088         1718 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000088 DAVHKZ010000000
VERSION     DAVHKZ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1718
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.088"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            436..1146
                     /gene="deoD"
                     /locus_tag="VVO74_002210"
     CDS             436..1146
                     /gene="deoD"
                     /locus_tag="VVO74_002210"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU5696146.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1169..1402)
                     /locus_tag="VVO74_002211"
                     /pseudo
     CDS             complement(1169..1402)
                     /locus_tag="VVO74_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
     gene            1528..>1718
                     /locus_tag="VVO74_002212"
     CDS             1528..>1718
                     /locus_tag="VVO74_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5696147.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     DCGSLMKKYDFQKPSKIPYL"
BASE COUNT          525 a          325 c          347 g          521 t
ORIGIN      
        1 ggtttgaaga gattttcgaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaaacaaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa agaaaggaat tgaccccacc
      181 ctaaaagcag tgggaaaaag atagttggtc tagcgagcat cgctcactgc gcccaactcc
      241 tattttccct tcgctttttg acgggtttgg tatctttctc aatataaaat ataaaataaa
      301 gaaaggtaga gcgtgtgttt tgatttgaac acgagcggaa aactcggaaa atagataatc
      361 tgactgaaaa atcaggattt ctcgtcggct tcctaatttt cagtcgtttt cttctcgctc
      421 tttgtatcat aaattatgtc tatccatatt gctgctcagc agggtgaaat tgctgataaa
      481 attcttcttc ctggggatcc tcttcgtgct aagtttattg cggagaattt ccttggtgat
      541 gctgtttgtt ttaacgaagt gcgtaacatg tttggttaca ctggtactta caagggtcac
      601 cgtgtatctg tcatgggaac tgggatggga atgccatcta tttcgattta tgcgcgtgag
      661 ttaatcgtag actacggtgt gaagaaattg attcgtgtgg gaactgcagg ttctttgaat
      721 gaagaggttc atgttcgtga attagttttg gcgcaggcgg ctgcaaccaa ctcaaacatc
      781 gttcgtaatg actggccaca gtacgatttt ccacaaattg ctagctttga tttgcttgat
      841 aaagcctacc atatcgccaa agaacttggt atgactactc acgttgggaa cgttttgtca
      901 tctgatgtct tttactcaaa ttactttgaa aagaatatcg agcttggtaa atggggagtc
      961 aaggctgtgg aaatggaagc agcagctctt tactatcttg ctgcccaata ccatgttgat
     1021 gcgctagcta tcatgaccat ctctgatagc ttggtcaatc cagacgaaga cacaactgca
     1081 gaagaacgtc aaaatacctt cactgatatg atgaaggttg gtttggaaac cttgattgca
     1141 gaataattat agccaaaaag gaagcccttt atgaattgta ggacttcctt ttcttatcca
     1201 gaaattgatc tagctctctc tgatttcgaa gaatagtgac tttatgtgaa tattcttggc
     1261 aaagtttttg gtaattttct ttttgagttt tgctacgtcc atcccaaaga atccatctga
     1321 taaactccca gtcaaagcgt tcagggcaat ctgccgccat actttctctg acttttccac
     1381 ggtatttaag ataacgctta aagggctcta taatatttgt agtgggtaaa tccactatag
     1441 atattatgga gcctattttt gtgtagaaaa aaagtcccat atgacctata atgaaaagcg
     1501 acaaaacaac tcattagaaa gaatcatatg gaacaattac attttatcac aaaattacta
     1561 gacattaaag accctaatat ccagatttta gacatcatca ataaagatac acacaaggaa
     1621 atcatcgcca aactggacta cgacgcccca tcttgccctg attgtggaag tctaatgaag
     1681 aaatatgact ttcaaaaacc gtctaagatc ccttacct
//
LOCUS       DAVHKZ010000089         1494 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000089 DAVHKZ010000000
VERSION     DAVHKZ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1494
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.089"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..>1494
                     /locus_tag="VVO74_002213"
     CDS             <1..>1494
                     /locus_tag="VVO74_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate binding domain-containing protein"
                     /protein_id="HEU5696148.1"
                     /translation="MIEAVKTSANKDIASQIASYRQSVDGKFTDISSQITTYKQDVGG
                     QISGLSNRLTSSEQGTTTQISNISNRINSNKQGTDNQISNLKTQVATNKDNAERQMGR
                     ISDQVSANKANADSQFANVTNQLARKVETTDFQRVKETSKLYERILGNTENGIADKVA
                     RMALTNQLFQVEVAKNASNGQNLLKGTKDFSGGWKNKGANWKKHAEKYKGVDVLFKNN
                     SWNGVGQEIDAKIGEVYTFSLWMKSDWKNDTVNFYVNRNGSVEKGWGVPSETSVAITS
                     EWKRYSFTFKITVDGFIFPRVERLNQNTNLYIAGLKLEKGSYATPYTEAPEDTDEAIR
                     SVQSQLTGSWAVQNINSAGDIISGINLGANGHNRFVGKLTHITGETLIDRAVIKSAMV
                     DKLKTGNFEAGSVTTTILDAEAVTAEKLKVDNALIRKLTANDAFIDQLISKRIFSIKV
                     ESVISSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAG"
BASE COUNT          489 a          271 c          342 g          392 t
ORIGIN      
        1 atgattgaag ctgttaaaac tagtgcgaat aaagacatcg ctagtcaaat cgctagctat
       61 cgtcaatctg tagatggtaa gttcacggat atttcaagtc agataactac ttataagcaa
      121 gatgtgggcg gtcaaatcag tggcctttca aatagactta caagcagtga gcaaggaacc
      181 actactcaga tttcaaatat ttcaaatcgg ataaacagta ataaacaagg cacagataat
      241 cagatttcaa atttaaagac tcaggtcgct acaaacaagg ataatgctga acgacaaatg
      301 ggtagaatat ctgatcaggt ttctgcaaac aaagcgaatg ctgatagtca atttgcgaat
      361 gtgaccaatc aactagcgcg aaaagtagag actactgact tccagcgtgt taaggaaacc
      421 agtaaacttt acgagcgaat tttgggcaat actgaaaatg gaattgcgga taaggttgct
      481 cgcatggctc tgactaatca actgtttcag gttgaggtgg ctaaaaatgc cagcaatggt
      541 caaaatttgt tgaaaggcac aaaagacttc tcagggggtt ggaaaaacaa gggtgcaaat
      601 tggaaaaagc acgctgaaaa atacaaaggt gttgatgtcc tatttaaaaa taattcgtgg
      661 aatggcgttg gacaagagat tgatgcaaaa attggtgaag tctatacatt cagcttatgg
      721 atgaagagcg actggaagaa tgatacagta aatttctatg taaatagaaa tggatctgtt
      781 gagaaaggtt ggggtgttcc atctgaaaca tcggtcgcta taacaagtga atggaaacgt
      841 tactcattta ccttcaaaat tactgtggac ggcttcatct ttcctcgtgt agaacgactt
      901 aatcaaaata caaatctata tattgcaggt cttaaacttg aaaaaggatc gtatgcaaca
      961 ccgtacaccg aagctcctga agacacggac gaagcgattc gctctgttca aagtcaacta
     1021 actggctcat gggcagttca aaacatcaac tcggctggag atatcatctc tggaatcaat
     1081 cttggcgcca atggacataa ccgctttgtt gggaaattga cccacatcac tggagagacc
     1141 ctgattgaca gagcagtcat caagtctgcc atggttgata agctcaaaac gggcaatttt
     1201 gaagctggtt cggtcacgac tacgatatta gatgctgaag cggtaactgc tgagaagttg
     1261 aaagttgaca atgcgcttat tagaaaatta actgcaaatg atgcttttat tgaccaactg
     1321 atatctaaac gtatcttctc tattaaggtt gagtccgtca tttctagctc aaccttccta
     1381 gaagcctatc aaggccgaat cggtggattc acacttggtc aatttgacca gggtggcggt
     1441 cgctggattt caggtgtcaa tcagttctct gttggtatgg ggaatggtgc cggg
//
LOCUS       DAVHKZ010000090          776 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000090 DAVHKZ010000000
VERSION     DAVHKZ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..776
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.090"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..>776)
                     /locus_tag="VVO74_002214"
     CDS             complement(<1..>776)
                     /locus_tag="VVO74_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696149.1"
                     /translation="NELAGVKSAQATYKETTTRRLSELTNLANGKASKSELTQTAEEL
                     ASRIASVQAGSSRNYFRNSRSRTFTTGGQAVYDYRTFIVPDFWKNSDRFKRDYVRISF
                     DVTFPVALVNDMPAMVHFSAHPWYAYRNLIFKGGTVERQHFEFTIDLSSSSEDYQTNN
                     VFIRFGTNYGFPAGLQVVIENAMLSVGNYFPAYQPAYEDQEDRVSVVESNFKQRADSL
                     EAGVSRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQN"
BASE COUNT          210 a          185 c          163 g          218 t
ORIGIN      
        1 ttgttctgcg tgtctgtctc aagactcttc acagattgcc ggatattttc agcagtcaca
       61 ttgagtgagc tgatatcggc tttggttcta aggccttcag tcagacggct tacaccagct
      121 tcgagtgaat cagcacgctg tttaaagttg gattcgacta ctgagacacg gtcttcttgg
      181 tcttcatacg ctggttgata ggctggaaaa taattaccaa ccgataacat agcgttctca
      241 atgacgacct gcagaccagc aggaaatcca taattagtac caaaacgaat gaacacatta
      301 ttagtctgat agtcctcaga agaactagac aagtcaatcg taaactcaaa atgttggcgt
      361 tcgacagttc cacctttaaa aattaagttt ctgtaggcat accatggatg agcactaaaa
      421 tgcaccatag caggcatgtc atttactagg gcgacaggga aagtcacatc aaaagatatg
      481 cgaacataat cacgcttgaa cctgtcactg ttcttccaga aatcaggaac tatgaatgtt
      541 cgatagtcgt ataccgcttg acctcctgtt gtgaacgttc ttgaacgtga attcctgaag
      601 taattccgtg aactacctgc ctgcacactc gcaatccgac tagctagctc ctcagctgtc
      661 tgcgtaagtt ctgacttgct ggctttacca ttggccaagt tggtcagttc tgacagtcta
      721 cgagtcgtcg tctccttata cgtcgcttgc gctgacttca cgccagccag ttcatt
//
LOCUS       DAVHKZ010000091          743 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000091 DAVHKZ010000000
VERSION     DAVHKZ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..743
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.091"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..>743
                     /locus_tag="VVO74_002215"
     CDS             <1..>743
                     /locus_tag="VVO74_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEU5696150.1"
                     /translation="NELAGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEEL
                     ASRIASVQASGRNLFLNSLFKQDISKTGIWTTSTYTATIDSESKYLGYNALKIIGLNP
                     SGRDGGNPKVTYPVLGQFGKVIPGSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTG
                     NVTLSTEIKRYVVHIPKGWTNESKQTTNEWLFNFNQEGTVWIWMPKFEISDVDTSYSE
                     APEDIEGQISTVESTFKQRVNSLEAGVNRL"
BASE COUNT          247 a          137 c          174 g          185 t
ORIGIN      
        1 aatgaactgg ctggcgtgaa gtcagcgcaa gcgacgtatg aggagacgac gactcgtaga
       61 ctgtcagaac tgaccaactt ggccaatggt aaagccagca agtcagaact cacgcagaca
      121 gctgaggagc tagctagtcg gattgcgagt gtgcaggcat ccggtcgaaa tctattcttg
      181 aactcactat tcaagcagga tatttcaaaa acaggaattt ggacaacgag tacatatacg
      241 gctactatcg atagcgaaag taagtatctt ggatataacg ctcttaaaat tataggtctg
      301 aatccatctg gccgtgatgg agggaatccc aaggttactt atccagttct gggtcaattc
      361 gggaaagtaa ttcccggaag tacgactaat caagatgtaa ccattagttt ttatgctaag
      421 gcaaataaaa atggaataat gctaagatct cgattaggga atatcggata taaaactgga
      481 aatgtgacat tgtcgacaga aattaaacga tatgttgtcc atattccaaa aggttggaca
      541 aacgaatcca agcagaccac aaatgaatgg ttgttcaatt tcaaccagga aggaaccgtt
      601 tggatttgga tgccgaagtt tgaaataagc gatgtagata cttcttattc agaagctcct
      661 gaagatatag aaggtcagat ttcaacagtt gaatcgacct ttaaacaacg agtcaactcg
      721 ctcgaagctg gtgtgaatcg tct
//
LOCUS       DAVHKZ010000092          739 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000092 DAVHKZ010000000
VERSION     DAVHKZ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..739
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.092"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..>739
                     /locus_tag="VVO74_002216"
     CDS             <1..>739
                     /locus_tag="VVO74_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696151.1"
                     /translation="TKDKASKSELTQTAEELSSKIASVQASGRNLFLNSLFKQDIPKT
                     GIWTTSTYTATIDSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGSTT
                     NQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQTT
                     NEWLFNFNQEGTIWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRANSLEAGV
                     NRLTEGLRTKVDISALNVTAENIRQSVK"
BASE COUNT          254 a          139 c          165 g          181 t
ORIGIN      
        1 aaccaaggat aaagccagca agtcagaact cacgcagaca gctgaggagc tctctagtaa
       61 gatagcgagt gtgcaggcat ccggtcgaaa tctattcttg aactcactat tcaagcagga
      121 tattccaaaa acaggaattt ggacaacgag tacatatacg gctactatcg atagcgaaag
      181 taagtatctt ggacataagg ctcttaaaat tataggtctg aatccatctg gccgtgatgg
      241 aggtaatccc aaggttactt atccagctct gggtcaattc gggaaagtaa ttcccggaag
      301 tacgactaat caagatgtaa ccattagttt ttatgctaag gcaaataaaa atggaataat
      361 gctgagatct cgattaggga atatcggata taaaactgga aatgtgacat tgtcgacaga
      421 aattaagcga tatgttgtcc atattccaaa aggttggaca aacgaatcca agcagaccac
      481 aaatgaatgg ttgttcaatt tcaaccagga aggaaccatt tggatttgga tgccgaagtt
      541 tgaaataagc gatgtagata cttcttattc agaagctcct gaagatatag aaggtcagat
      601 ttcaacagta gaatcgacct tcaaacaacg agccaactcg ctcgaagctg gtgtgaatcg
      661 tctgactgaa ggccttagaa ccaaagtaga tatcagcgca ctcaatgtga ctgctgaaaa
      721 tatccggcaa tctgtgaag
//
LOCUS       DAVHKZ010000093          717 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000093 DAVHKZ010000000
VERSION     DAVHKZ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..717
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.093"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            133..666
                     /gene="queF"
                     /locus_tag="VVO74_002217"
     CDS             133..666
                     /gene="queF"
                     /locus_tag="VVO74_002217"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEU5696152.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQINREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISINPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT          217 a          172 c          137 g          191 t
ORIGIN      
        1 ttttactata taagtagaat attacgatgt ttgggatatg ccatcgctaa aaaaactcga
       61 tttggtattt tttagctccc taatgggagc tttttgcatg ctctgaacat ttcccatttt
      121 ggaaggagta ctatgaaacg tcaatcagcc ttggtcgtct ttagtggtgg tcaagattca
      181 acaacctgcc ttttctgggc catgcaacac tatgaaacag tcgaagctgt cacctttgcc
      241 tacggccaac gtcatcacct cgaaattcaa attaatagag aaatcgctaa ggaacagggc
      301 attcgtcacc atatcctcga tatgtctctg ctgggacaaa tcactgctca gccagacttt
      361 gcgacgattc atatttccta cattcctgac aaactctgtg tcgagtcaaa atccctcaaa
      421 ctatatctat ttagctaccg aaaccacgga gatttccacg aaaactgtat caacaccatc
      481 gggaaagact tggtcaactt gctagaccct cgctatttag aagtctgggg gaaattcact
      541 ccgcgcggtg gcatttcaat caacccctac tacaactacg gtaagcaagg aactaagtat
      601 gagggcttgg cagaacaacg cctcttccaa cacgaccttt atccagagaa aattgacaac
      661 cgctaaagtc atactcaatg aaaatcaaag agcaaactag gaagttagcc gcaggtt
//
LOCUS       DAVHKZ010000094          695 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000094 DAVHKZ010000000
VERSION     DAVHKZ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..695
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.094"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(304..615)
                     /locus_tag="VVO74_002218"
     CDS             complement(304..615)
                     /locus_tag="VVO74_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5696153.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
BASE COUNT          226 a          127 c          111 g          231 t
ORIGIN      
        1 catatcgtaa aggtcgtatt tccaacggca tgactgagaa catccaccac ggttggcatc
       61 acgcatactc tagacgcaat tctaatcttt tagactttgc ataataactg ttaaacagtt
      121 gaaaattaac ccagttttaa caagtagtca aaataccaga taaaggaaaa aagtctttaa
      181 aatcttaaaa acgcatagta tcaggtattg aacaatcttg atattatgcg ttttattgtg
      241 ggaagattta cttcattttc tcttggaatt gagttttctc ctacttcaaa actagatgat
      301 ttgctattta aaatagcgtt ccttatgatt ttggcaacct ggattaaagc gagaaaaaca
      361 aaaggggcaa cttaagcttt ctttatattg cttatatgtt agtagtttta gacaaacacc
      421 acataaaata ggcttatcct gtatcaaaga taagggatac ggctcaaaag ggtgattttc
      481 taatgaatca tgacaccgat aacaagcata atacttttta caatcatagc attgtaaagc
      541 aataatatcc agcttgctat ggtaatgaat gcatcttgtt tgcttatcca ctaagaaacc
      601 ctgtgcctct atcatttcct tttcctttct taagctcgaa ctgtgacgct ggttccatct
      661 tccttataaa gattgatgag tccttctttt aatgc
//
LOCUS       DAVHKZ010000095          680 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000095 DAVHKZ010000000
VERSION     DAVHKZ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..680
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.095"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..261
                     /locus_tag="VVO74_002219"
     CDS             <1..261
                     /locus_tag="VVO74_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU5696154.1"
                     /translation="TDIVHNLAEKVVVVRLEKPVTFHNMIAPDKEVEVSLLFFIINNS
                     SSSQTNILAQLMNFFTGNGHLEDLSKISEPEKLYAYIDEAIA"
     gene            299..601
                     /locus_tag="VVO74_002220"
     CDS             299..601
                     /locus_tag="VVO74_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU5696155.1"
                     /translation="MIKILAACGAGVNSSHQIKSTLEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSAPVFDNIRLPAKQNMV"
BASE COUNT          227 a          126 c          127 g          200 t
ORIGIN      
        1 acagatattg ttcataatct agctgagaaa gtggtggttg ttcgattaga aaaaccagta
       61 acttttcaca atatgatagc tcccgataag gaagtagaag tatccctact cttctttatc
      121 attaataatt caagttcaag tcaaacgaac attcttgctc agttgatgaa cttcttcaca
      181 ggaaatggac atcttgaaga cctatcaaaa atttccgaac cagaaaaact ttatgcttat
      241 atagatgaag caatcgctta atcttgtcta ttaaaaaata aaatcggagg aagtctatat
      301 gattaaaatt cttgctgcct gcggtgcagg tgttaactca agtcaccaaa ttaaaagtac
      361 tctagaagaa gaactttcaa accgtggtta cgatgttcac tgtgatgcag tcatggtgaa
      421 agatgtaaac gaagacctta tgaaaggtta cgatatcttt acaccaatcg ctgcaacaga
      481 tcttggtttt gaaccaggta tcccagttat cgaagctggg ccaatcttat tttgtatccc
      541 agcaatgagc gctccagtat ttgacaatat tagactccct gcgaaacaaa atatggtata
      601 gtagttctat gaatgatgaa gcaagtaaac aactaaccga tgcacgattt aagcgtcttg
      661 ttggtgttca gcgtaccact
//
LOCUS       DAVHKZ010000096          660 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000096 DAVHKZ010000000
VERSION     DAVHKZ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..660
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.096"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..>660
                     /locus_tag="VVO74_002221"
     CDS             <1..>660
                     /locus_tag="VVO74_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5696156.1"
                     /translation="NQDCLIALKLLSDPNREQFQHDNRQVDLKILARHIHRLKKKQSD
                     WKVQYTRCLDIIFPELDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASK
                     IQDILSVAPRSIGTTSPAREFEIIEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGI
                     GGRLGAVILAEIRNIHAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWAL
                     I"
BASE COUNT          195 a          147 c          132 g          186 t
ORIGIN      
        1 tcaaccaaga ctgtctcatc gctcttaaac ttctttctga ccccaatcgt gaacaatttc
       61 aacacgataa tcggcaagta gacctaaaaa tactggctag acatattcat cgtctcaaga
      121 aaaaacagtc tgattggaaa gtacaataca ctcgttgtct tgatatcatc tttcctgagt
      181 tggataaaat cgttggaaag cattcagaat atacctacca actcttgacg cgctacccta
      241 atcctcagaa aaggattgag gcaggatttg ataagctgat agaaattaag cgattgaccg
      301 cttctaaaat tcaggatatc ctctcagtcg cacctcgttc tatcggaaca acatctcctg
      361 ctcgtgaatt cgaaatcatc gaaatcatca aacattacaa gaggctcatt gacaaggcgg
      421 aaacatgtgt caatgacttg atggctgagt tcaactcagt catcacgacg gttactggga
      481 ttgggggtcg tttaggggcg gtcattttag ccgagattcg aaatattcat gcctttgata
      541 atcctgctca attacaagct ttcgctggac tggattcttc tatttatcag tcaggtcaga
      601 ttgatttagc tggaagaatg atcaaacggg gttcccctca tctgcggtgg gcactcatac
//
LOCUS       DAVHKZ010000097          651 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000097 DAVHKZ010000000
VERSION     DAVHKZ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.097"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..>651
                     /locus_tag="VVO74_002222"
     CDS             <1..>651
                     /locus_tag="VVO74_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HEU5696157.1"
                     /translation="RCQVKIITMDMFSPYYDLAKQLFPCAKIVLDRFHIIQHLSRAMS
                     RFRVQIMNQFERKSHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRIHLTNKEILDKIL
                     SYSEDLKHHYQIYQLLLFHFQNKDPEKFFGLIEDNLKQVHPIFQTVFKTFLKNKEKIV
                     NALQLPYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSQA"
BASE COUNT          220 a          135 c           96 g          200 t
ORIGIN      
        1 cgttgtcaag tgaaaatcat tacgatggat atgtttagtc cttactatga cttggctaaa
       61 cagctttttc cgtgtgctaa aatcgttcta gatcgtttcc atattatcca acatctcagc
      121 cgtgccatga gtcgttttcg tgttcaaatt atgaatcagt ttgaacgaaa atctcatgaa
      181 tacaaggcta tcaagcgtta ctggaaactc atccaacagg atagtcgtaa actcagcgat
      241 aaacgttttt atcgccctac ttttcgcata cacttaacaa ataaagaaat tcttgacaag
      301 attttaagct attcagaaga cttgaaacac cactatcaga tctatcaact cttacttttt
      361 cactttcaga acaaagaccc tgagaaattt ttcggactca ttgaggacaa tctgaagcag
      421 gttcatccta tttttcagac tgtctttaaa acctttctaa agaacaaaga aaaaatcgtc
      481 aatgctcttc aattacctta ttccaatgca aaattggaag cgaccaataa tctcatcaaa
      541 cttatcaaac gaaacgcctt tggatttcgg aactttgaaa acttcaaaaa aaggattttt
      601 atcgctctga acatcaaaaa agaaaggacg aaatttgtcc tttctcaagc t
//
LOCUS       DAVHKZ010000098          622 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000098 DAVHKZ010000000
VERSION     DAVHKZ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..622
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.098"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            105..584
                     /locus_tag="VVO74_002223"
     CDS             105..584
                     /locus_tag="VVO74_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU5696158.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRKYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          235 a           81 c          142 g          164 t
ORIGIN      
        1 gcctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtgtataagt gtagaaatga atattacctt catttatggg
      181 aattatcgga ttgggaccaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggt agacgatatt ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aagcaggaaa gtcagaagcg taaatacgat aaagaaccct
      361 atgaagaagt gggtgagatc agtcatcgta taagtgaggg gggtctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgcgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ctagtaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gt
//
LOCUS       DAVHKZ010000099          611 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000099 DAVHKZ010000000
VERSION     DAVHKZ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.099"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            246..611
                     /locus_tag="VVO74_002224"
                     /pseudo
     CDS             246..611
                     /locus_tag="VVO74_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT          204 a          106 c          125 g          176 t
ORIGIN      
        1 tataatgctt tttgatttta gtctagtata aatagcgaga aatatctatc ctatcttcta
       61 gaatgtcttc caaacgagga aactctcgta aacaaagagg ttttagaggc ctatttaccg
      121 tggactaaag ttgtacaaga aaagtgcaaa taagaaatct ccagattagg aactatccgt
      181 gagttctcta gtctggagat ttttcaatag acttcctgcg aaacaaaata tggtataata
      241 gttctatgaa ttatgaagca agtaaacaac taaccgatgc acgatttaag cgtcttgttg
      301 gtgttcaacg cacgactttt gaagagatgt tagctgtatt aaaaacagct tatcaactta
      361 aacacgcaaa aggtgggcga aaacctaaat taagcctaga agaccttctt atggccactc
      421 ttcaatatgt gcgagaatat cgaacttatg aagaaattgc ggctgatctt ggtattcacg
      481 aaagcaactt aatccgtcgg agccaatggg ttgaagtaac tcttgttcaa aggtggtgtt
      541 gcgatttcaa gaactcctct cagttctgag gacacggtaa tgattgatgc gacggaagta
      601 aaaatcaatc g
//
LOCUS       DAVHKZ010000100          550 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000100 DAVHKZ010000000
VERSION     DAVHKZ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..550
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.100"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..>550
                     /locus_tag="VVO74_002225"
     CDS             <1..>550
                     /locus_tag="VVO74_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU5696159.1"
                     /translation="LQGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHY
                     VSTVTNCYKAAVDAYLESPEKFEAIKQDLVDEMWKVAQRELATGFYYGTPSENEQLFG
                     ARRKIPEYKFVAEVVSYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDA
                     KGNKIDRAPNPMELLTIKVPQPV"
BASE COUNT          167 a          105 c          128 g          150 t
ORIGIN      
        1 gtttgcaggg tgagattcca gaagaatttt caatgtcagc cgttgacatg tctatgattg
       61 accacattcc agatatgatt gaaaatggtg tggacagtct aaaaatcgaa ggacgtatga
      121 agtctattca ctacgtatca acagtaacca actgctacaa ggcggctgtg gatgcctatc
      181 ttgaaagtcc tgaaaagttt gaagctatca aacaagactt ggtggacgag atgtggaagg
      241 ttgcccaacg tgaactggct acaggatttt actatggtac accatctgaa aatgagcagt
      301 tgtttggtgc tcgccgtaaa attcctgagt acaagtttgt cgctgaagtg gtttcttatg
      361 atgatgcggc acaaacagca acaattcgtc aacgaaatgt cattaacgaa ggggaccaag
      421 ttgagtttta tggtccaggt ttccgtcatt ttgaaaccta tattgaagat ttgcatgatg
      481 ccaaaggcaa taaaatcgac cgcgctccaa atccaatgga actattgact attaaggtgc
      541 ctcaacccgt
//
LOCUS       DAVHKZ010000101          529 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000101 DAVHKZ010000000
VERSION     DAVHKZ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.101"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..>529
                     /locus_tag="VVO74_002226"
     CDS             <1..>529
                     /locus_tag="VVO74_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5696160.1"
                     /translation="QILDIINKDTHKEIIAKLDYDAPSCPECGSQMKKYDFQKPSKIP
                     YLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQIPRIINQKIAQKLIEKISM
                     TDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYAFTKGKMSFIAQDFDNLNI
                     ITVLEGRTQAVIRNH"
BASE COUNT          173 a          117 c           85 g          154 t
ORIGIN      
        1 tccagatttt agacatcatc aataaagata cacacaagga aatcatcgcc aaactggact
       61 acgacgcccc atcttgccct gagtgcggaa gtcaaatgaa gaaatatgac tttcaaaaac
      121 cttctaaaat tccttatctt gaaacaactg gtatgccttc tagaattctc cttagaaaac
      181 gccgtttcaa gtgctatcac tgttcaaaaa tgatggttgc tgagactccc ctggtaaaga
      241 aaaatcacca aatccctcgt atcatcaacc aaaaaattgc tcaaaagtta attgaaaaaa
      301 tttctatgac tgatattgcc catcagctgg ccatttcaac ttcaactgtc attcgcaagc
      361 tcaatgactt tcactttgag catgattttt ctcggcttcc aaagattatg tcttgggatg
      421 agtatgcctt cactaaggga aagatgagtt tcattgcgca agattttgat aatcttaata
      481 ttatcactgt tcttgaaggc agaacacaag ctgtcatccg aaatcactt
//
LOCUS       DAVHKZ010000102          524 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000102 DAVHKZ010000000
VERSION     DAVHKZ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..524
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.102"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..>524)
                     /locus_tag="VVO74_002227"
     CDS             complement(<1..>524)
                     /locus_tag="VVO74_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5696161.1"
                     /translation="NTVLSRLGDLSLPCPQDEDLTILPHSAYSETLYQAGSWSHKRRV
                     CQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIKEMKEGFFGDKTDS
                     STLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLHVVGKCVRTGRKQL
                     LKLSSLYAYSELFS"
BASE COUNT          150 a          106 c          125 g          143 t
ORIGIN      
        1 ctgaaaacaa ttcggaatag gcatagagac tagacaattt gaggagctgc ttgcgtcctg
       61 ttcgaacaca ttttcctacc acgtgaagaa aaagatggcg gaagcgtttg attgttaaag
      121 tttggaagtc acctccagct agatgtttga gaaaaagata gagattgtag gcgatacagc
      181 tcatcatcat acgaacttcg tttttgatta aggttgaact atccgtttta tcgccaaaaa
      241 atccctcctt catctccttg atgaaattct cggcttgacc acgtccacga taaagctgaa
      301 actggtcttg gcttgttcca ctcgtcatat ttgtaacgag agaaataaca tcgtagaaca
      361 agtttccttc ttttcgttca gagaactggc agacacgacg cttgtgcgac caagatcctg
      421 cttgatagag agtttctgag taggcggagt ggggcaagat ggttaagtcc tcatcctgtg
      481 ggcaagggag ggaaaggtct ccaagacggc tcagaacagt attt
//
LOCUS       DAVHKZ010000103          439 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000103 DAVHKZ010000000
VERSION     DAVHKZ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.103"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..>439)
                     /locus_tag="VVO74_002228"
     CDS             complement(<1..>439)
                     /locus_tag="VVO74_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5696162.1"
                     /translation="KELSADAYFPKLLEGGQLASQPTLSRFLSRTDEETVHSLRCLNL
                     ELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEGVAYNAHYRAHGYHPLYAFEGKTGYCF
                     NAQLRPGNRYCSEEADSFITPVLERFNQLLFRMDSGFATPKLYD"
BASE COUNT          139 a           85 c          101 g          114 t
ORIGIN      
        1 aatcgtataa ttttggggtc gcaaagccac tatccattcg aaagagaagt tgattaaacc
       61 gttctaaaac aggtgtgata aagctgtctg cctcttcaga acaataacga ttaccaggac
      121 gaagctgggc attgaaacaa taacctgtct tcccctcgaa agcataaaga ggatgatagc
      181 catgagcacg atagtgggcg ttataagcaa caccttcttg cttgccataa gttgtgaaat
      241 gggtagaatc gatatctaca atgagttggt ttagctggtg aaactgtaaa aagaattcga
      301 ccaattcaag gttgaggcat cgcaaactat ggactgtttc ctcgtcagtt ctggaaagaa
      361 aacgggataa ggttggctgt gaagcaagct gccctccttc caacaatttt ggaaagtagg
      421 catcagctga caattcttt
//
LOCUS       DAVHKZ010000104          434 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000104 DAVHKZ010000000
VERSION     DAVHKZ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.104"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..>434)
                     /locus_tag="VVO74_002229"
     CDS             complement(<1..>434)
                     /locus_tag="VVO74_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU5696163.1"
                     /translation="IPASTQKLYLSPVLDGFNSEIIAYNLSTSPNLEQVQTMLEQVFT
                     EKHYENTILHSDQGWQYRHDSYHRFLESKGIQASMSRKGNSPDNGMMESFFGILKSEM
                     FYGYEKSFQSLKQLEQAIVDYVDYYNNKRIKVKLKGLSPVQY"
BASE COUNT          120 a           85 c           84 g          145 t
ORIGIN      
        1 gtactgcaca ggactaagtc cttttagttt taccttaatt cgtttattgt tgtagtaatc
       61 aacatagtct acaatagctt gttccaattg cttaagcgac tgaaacgact tctcataacc
      121 gtaaaacatt tccgatttca gaatcccaaa gaaggactcc atcataccat tgtctgggct
      181 gttaccctta cgtgacatag atgcttgaat tcccttactc tctaggaacc gatgataaga
      241 atcgtgtcgg tattgccagc cttggtcact atggagaatc gtattctcat agtgcttctc
      301 tgtgaatacc tgttccaaca ttgtttgtac ttgttctaag ttgggtgaag ttgaaagatt
      361 ataggcgata atttcgctat taaagccatc taaaactggt gataagtaaa gcttttgagt
      421 acttgctgga atgg
//
LOCUS       DAVHKZ010000105          375 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP18
            SAMN04504901-rid19297753.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVHKZ010000105 DAVHKZ010000000
VERSION     DAVHKZ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504901
            Sequence Read Archive: SRR3211696
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869533.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869533.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 16:28:06
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,230
            CDSs (total)                      :: 2,184
            Genes (coding)                    :: 2,056
            CDSs (with protein)               :: 2,056
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 69 of 128
            Pseudo Genes (incomplete)         :: 56 of 128
            Pseudo Genes (internal stop)      :: 35 of 128
            Pseudo Genes (multiple problems)  :: 29 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504901-rid19297753.denovo.105"
                     /strain="SP18"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..>375
                     /locus_tag="VVO74_002230"
     CDS             <1..>375
                     /locus_tag="VVO74_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5696164.1"
                     /translation="DTHKEIIAKLDYDAPSCPECGNQLKKYDFQKPSKIPYLETTGMP
                     TRILLRKRRFKCYHCSRMMVAETSIVKKNHQIPRIINQKIAQKLIEKISMTDIDHQLS
                     ISTSTVIRKINDFHFKHDFSCLP"
BASE COUNT          120 a           83 c           58 g          114 t
ORIGIN      
        1 gatacacaca aggaaatcat cgccaaactg gactacgacg ccccatcttg ccctgagtgc
       61 ggaaatcaat tgaagaaata tgactttcaa aaaccttcta aaattcctta tcttgaaacg
      121 actggtatgc ctactagaat tctccttaga aagcgtcgtt tcaagtgcta tcactgttca
      181 agaatgatgg tcgctgaaac ttctatcgtc aagaagaatc accaaattcc tcgtattatc
      241 aaccaaaaaa ttgcgcaaaa gttgattgag aagatttcta tgaccgacat tgatcatcag
      301 ttgtctattt caacttcaac tgtcattcgc aagatcaatg attttcactt taaacatgat
      361 ttttcttgtc ttcct
//
